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ATE372339T1 - Zwischenprodukte für die herstellung von imidazo- pyridin-derivate - Google Patents

Zwischenprodukte für die herstellung von imidazo- pyridin-derivate

Info

Publication number
ATE372339T1
ATE372339T1 AT04023090T AT04023090T ATE372339T1 AT E372339 T1 ATE372339 T1 AT E372339T1 AT 04023090 T AT04023090 T AT 04023090T AT 04023090 T AT04023090 T AT 04023090T AT E372339 T1 ATE372339 T1 AT E372339T1
Authority
AT
Austria
Prior art keywords
production
intermediate products
imidazopyridine derivatives
imidazopyridine
derivatives
Prior art date
Application number
AT04023090T
Other languages
English (en)
Inventor
Kosrat Amin
Mikael Dahlstroem
Peter Nordberg
Ingemar Starke
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE372339T1 publication Critical patent/ATE372339T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT04023090T 1998-04-29 1999-04-23 Zwischenprodukte für die herstellung von imidazo- pyridin-derivate ATE372339T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9801526A SE9801526D0 (sv) 1998-04-29 1998-04-29 New compounds

Publications (1)

Publication Number Publication Date
ATE372339T1 true ATE372339T1 (de) 2007-09-15

Family

ID=20411154

Family Applications (4)

Application Number Title Priority Date Filing Date
AT99947038T ATE312101T1 (de) 1998-04-29 1999-04-23 Imidazo-pyridin verbindungen, die die sekretion von magensäure hemmen
AT99947037T ATE307130T1 (de) 1998-04-29 1999-04-23 Imidazo-pyridin verbindungen, die die sekretion von magensäure hemmen.
AT04023091T ATE372340T1 (de) 1998-04-29 1999-04-23 Zwischenprodukte für die herstellung von imidazo- pyridin-derivate
AT04023090T ATE372339T1 (de) 1998-04-29 1999-04-23 Zwischenprodukte für die herstellung von imidazo- pyridin-derivate

Family Applications Before (3)

Application Number Title Priority Date Filing Date
AT99947038T ATE312101T1 (de) 1998-04-29 1999-04-23 Imidazo-pyridin verbindungen, die die sekretion von magensäure hemmen
AT99947037T ATE307130T1 (de) 1998-04-29 1999-04-23 Imidazo-pyridin verbindungen, die die sekretion von magensäure hemmen.
AT04023091T ATE372340T1 (de) 1998-04-29 1999-04-23 Zwischenprodukte für die herstellung von imidazo- pyridin-derivate

Country Status (34)

Country Link
US (2) US6313137B1 (de)
EP (4) EP1491543B1 (de)
JP (2) JP3883383B2 (de)
KR (3) KR100595806B1 (de)
CN (2) CN1165535C (de)
AR (2) AR015768A1 (de)
AT (4) ATE312101T1 (de)
AU (2) AU769190B2 (de)
BR (2) BR9909995B1 (de)
CA (2) CA2329922C (de)
CZ (2) CZ292567B6 (de)
DE (4) DE69937076T2 (de)
DK (2) DK1073657T3 (de)
EE (2) EE04676B1 (de)
ES (2) ES2252975T3 (de)
HK (5) HK1033457A1 (de)
HU (2) HUP0102425A3 (de)
ID (2) ID27530A (de)
IL (4) IL139200A0 (de)
IS (2) IS5684A (de)
MY (2) MY121379A (de)
NO (2) NO318203B1 (de)
NZ (2) NZ507639A (de)
PL (2) PL195000B1 (de)
RU (2) RU2235725C2 (de)
SA (2) SA99200065B1 (de)
SE (1) SE9801526D0 (de)
SI (1) SI1073656T1 (de)
SK (2) SK285768B6 (de)
TR (4) TR200003176T2 (de)
TW (2) TW490466B (de)
UA (2) UA67769C2 (de)
WO (2) WO1999055706A1 (de)
ZA (2) ZA200005796B (de)

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* Cited by examiner, † Cited by third party
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US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
SE9802794D0 (sv) * 1998-08-21 1998-08-21 Astra Ab New compounds
SE0003186D0 (sv) * 2000-09-07 2000-09-07 Astrazeneca Ab New process
US6900324B2 (en) 2000-09-07 2005-05-31 Astrazeneca Ab Process for preparing a substituted imidazopyridine compound
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
SE0100295D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100296D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
SE0100297D0 (sv) * 2001-02-01 2001-02-01 Astrazeneca Ab New compounds
CA2434835A1 (en) * 2001-02-13 2002-08-22 Astrazeneca Ab Novel modified released formulation
EE05234B1 (et) * 2001-03-08 2009-12-15 Astrazeneca Ab 6-karboksamidoimidaso[1,2-a] pridiinihendite kasutamine ravimi p?hjustatud maohaavandi v„ltimiseks
SE0102808D0 (sv) * 2001-08-22 2001-08-22 Astrazeneca Ab New compounds
MY140561A (en) * 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
SE0201939D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination
SE0201940D0 (sv) * 2002-06-20 2002-06-20 Astrazeneca Ab New combination II
NZ538566A (en) 2002-09-19 2008-02-29 Schering Corp Imidazopyridines as cyclin dependent kinase inhibitors
CN100384842C (zh) 2002-11-19 2008-04-30 奥坦纳医药公司 8-取代的咪唑并吡啶类化合物
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
AP2114A (en) * 2003-02-26 2010-03-04 Sugen Inc Aminoheteroaryl compounds as protein kinase inhibitors
DE602004023921D1 (de) 2003-03-10 2009-12-17 Nycomed Gmbh Neues verfahren zur herstellung vonroflumilast
SE525349C2 (sv) * 2003-06-23 2005-02-08 Volvo Penta Ab Utombordsdrev för båtar
SE0301905D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound I with therapeutic effect
SE0301904D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound II with therapeutic effect
SE0301903D0 (sv) * 2003-06-26 2003-06-26 Astrazeneca Ab Novel imidazopyridine compound III with therapeutic effect
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
AU2004285394B2 (en) * 2003-11-03 2009-01-08 Astrazeneca Ab Imidazo (1,2-A) pyridine derivatives for the treatment of silent gastro-esophageal reflux
SE0303451D0 (sv) * 2003-12-18 2003-12-18 Astrazeneca Ab New compounds
EP1711498A2 (de) * 2004-01-26 2006-10-18 Altana Pharma AG 1,2,4-triazolo[1,5-a]pyridine als inhibitoren der sekretion von magensäure
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
AP2007004023A0 (en) * 2004-12-17 2007-06-30 Pfizer Chromane derivatives useful as acid pump antagonists
AU2006224619B2 (en) 2005-03-16 2012-06-07 Takeda Gmbh Taste masked dosage form containing roflumilast
ES2470766T3 (es) * 2005-03-21 2014-06-24 Mei Pharma, Inc. Derivados de [1,2-a]piridina: preparación y aplicaciones farmacéuticas
US7666880B2 (en) 2005-03-21 2010-02-23 S*Bio Pte Ltd. Imidazo[1,2-A]pyridine derivatives: preparation and pharmaceutical applications
TW200700064A (en) * 2005-03-24 2007-01-01 Glaxo Group Ltd Novel compounds
GB0513423D0 (en) * 2005-06-30 2005-08-03 Glaxo Group Ltd Novel compounds
KR101146852B1 (ko) * 2005-12-05 2012-05-16 화이자 프로덕츠 인크. C?met/hgfr 억제제의 다형체
BRPI0619424B1 (pt) * 2005-12-05 2022-02-08 Pfizer Products Inc Uso de inibidores c-met/hgfrs para a fabricação de medicamentos
WO2007107827A1 (en) * 2006-03-17 2007-09-27 Raqualia Pharma Inc. Chromane derivatives
EP2054036B1 (de) 2006-07-24 2019-12-18 Singh-Broemer and Company, Inc. Feste nanoteilchenförmige formulierung von wasserunlöslichen pharmazeutischen substanzen mit verringerter ostwald-reifung
WO2008059373A1 (en) * 2006-11-17 2008-05-22 Raqualia Pharma Inc. Imidazo [1, 2-a] pyrazine derivatives and their use as acid pump antagonists
EP1974729A1 (de) * 2007-03-28 2008-10-01 Santhera Pharmaceuticals (Schweiz) AG Substituierte Imidazopyridinderivate als Melanocortin-4-Rezeptorantagonisten
US8513226B2 (en) * 2008-03-31 2013-08-20 Council Of Scientific And Industrial Research Simultaneous method for the preparation of a mixture of 3-acetoxy-17-acetamido-16-formyl-androst-5,17-diene and 3-acetoxy-2'-chloro-5-androsteno[17,16-b]pyridine
AU2014201644B2 (en) * 2008-12-03 2015-05-21 Cinclus Pharma Holding AB (publ) Imidazopyridine derivatives which inhibit the secretion of gastric acid
FI20086158A0 (fi) 2008-12-03 2008-12-03 Mikael Dahlstroem Imidatsopyridiinijohdannaiset
CN105919998B (zh) 2009-07-09 2021-08-24 拉夸里亚创药株式会社 用于治疗与异常肠胃运动有关的疾病的酸泵拮抗剂
BR112015030288B1 (pt) * 2013-06-25 2022-10-18 Ptc Therapeutics, Inc. Compostos e seu uso no tratamento de atrofia muscular espinhal
US9944637B2 (en) 2013-12-16 2018-04-17 Asana Biosciences, Llc P2X3 and/or P2X2/3 compounds and methods
JP6578298B2 (ja) * 2014-03-24 2019-09-18 アークル インコーポレイテッド 3−(3−(4−(1−アミノシクロブチル)フェニル)−5−フェニル−3h−イミダゾ[4,5−b]ピリジン−2−イル)ピリジン−2−アミンを調製する方法
CN106279151A (zh) * 2015-06-26 2017-01-04 江苏太瑞生诺生物医药科技有限公司 5-(2-(8-((2,6-二甲基苄基)氨基)-2,3-二甲基咪唑并[1,2-a]吡啶-6-甲酰胺基)乙氧基)-5-氧代戊酸的固体形式及其制备方法
KR101777971B1 (ko) * 2016-07-05 2017-09-12 제일약품주식회사 이미다조[1,2-a]피리딘 유도체, 이의 제조방법 및 이의 용도
KR20190057569A (ko) 2017-11-20 2019-05-29 제일약품주식회사 7-아미노-1h-인돌-5-카르복사미드 유도체 및 이의 용도
CN111683976B (zh) 2018-02-05 2022-11-18 生物辐射实验室股份有限公司 具有阴离子交换-疏水混合模式配体的色谱树脂
WO2019197232A1 (de) * 2018-04-10 2019-10-17 Bayer Aktiengesellschaft Verfahren zur herstellung von 2,6-dialkylphenyl-essigsäuren
RU2732297C2 (ru) * 2018-11-14 2020-09-15 Общество с ограниченной ответственностью "Гурус БиоФарм" Производные нестероидных противовоспалительных средств
CA3156073A1 (en) 2019-11-04 2021-05-14 Cinclus Pharma Holding AB Oral formulation of x842
CA3235361A1 (en) 2021-11-05 2023-05-11 Kjell JARRING Polymorphs of the hydrochloride salt of linaprazan glurate
CN118414334A (zh) 2021-11-05 2024-07-30 辛克鲁斯制药控股有限公司 (Publ) 谷氨酸利那拉生甲磺酸盐的多晶型物
KR102496869B1 (ko) * 2022-07-29 2023-02-07 제일약품주식회사 이미다조[1,2-a]피리딘 화합물의 신규 염, 이의 결정형 및 제조방법
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WO2024149833A1 (en) 2023-01-11 2024-07-18 Cinclus Pharma Holding AB (publ) Polymorphs of the maleic acid salt of linaprazan glurate
WO2024161317A1 (ko) * 2023-02-01 2024-08-08 제일약품주식회사 약학적 제제, 이의 제조 방법, 및 정제용 조성물

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GB8722488D0 (en) 1987-09-24 1987-10-28 Fujisawa Pharmaceutical Co Imidazopyridine compound

Also Published As

Publication number Publication date
EE04676B1 (et) 2006-08-15
IL139297A0 (en) 2001-11-25
BR9909995A (pt) 2000-12-26
ATE372340T1 (de) 2007-09-15
NO317262B1 (no) 2004-09-27
EE04916B1 (et) 2007-10-15
DK1073657T3 (da) 2006-03-13
CN1307577A (zh) 2001-08-08
IS5683A (is) 2000-10-25
IL139200A0 (en) 2001-11-25
JP3692034B2 (ja) 2005-09-07
TR200003176T2 (tr) 2001-03-21
PL343801A1 (en) 2001-09-10
KR100650472B1 (ko) 2006-11-28
ZA200005796B (en) 2002-01-18
DE69927803T2 (de) 2006-07-06
NZ507638A (en) 2003-10-31
JP2002513024A (ja) 2002-05-08
NO20005450D0 (no) 2000-10-27
WO1999055706A9 (en) 2000-03-16
CN1165535C (zh) 2004-09-08
DE69928792T2 (de) 2006-07-20
DE69937077D1 (de) 2007-10-18
MY121389A (en) 2006-01-28
ID26819A (id) 2001-02-15
CZ20003982A3 (cs) 2001-02-14
ES2249913T3 (es) 2006-04-01
SK285768B6 (sk) 2007-07-06
IL139297A (en) 2007-06-03
BR9909996B1 (pt) 2010-08-24
AU4300699A (en) 1999-11-16
US6313136B1 (en) 2001-11-06
AU4300799A (en) 1999-11-16
HK1033317A1 (en) 2001-08-24
DE69937077T2 (de) 2008-05-29
SK14912000A3 (sk) 2001-06-11
CA2329922A1 (en) 1999-11-04
SA99200064B1 (ar) 2006-10-11
ATE307130T1 (de) 2005-11-15
CZ292567B6 (cs) 2003-10-15
SI1073656T1 (sl) 2006-02-28
WO1999055706A1 (en) 1999-11-04
EP1491542A3 (de) 2005-01-05
HK1071139A1 (en) 2005-07-08
IS5684A (is) 2000-10-25
KR20010043133A (ko) 2001-05-25
ES2252975T3 (es) 2006-05-16
PL343797A1 (en) 2001-09-10
MY121379A (en) 2006-01-28
JP2002513025A (ja) 2002-05-08
UA66846C2 (uk) 2004-06-15
UA67769C2 (uk) 2004-07-15
CA2329921A1 (en) 1999-11-04
NO20005451L (no) 2000-12-27
AR015769A1 (es) 2001-05-16
DK1073656T3 (da) 2006-01-16
EE200000626A (et) 2002-04-15
US6313137B1 (en) 2001-11-06
RU2238271C2 (ru) 2004-10-20
EP1491542A2 (de) 2004-12-29
CZ20003981A3 (cs) 2001-03-14
DE69937076D1 (de) 2007-10-18
HUP0102313A3 (en) 2002-10-28
AU769190B2 (en) 2004-01-22
SK14922000A3 (sk) 2001-06-11
KR20010043134A (ko) 2001-05-25
KR100595806B1 (ko) 2006-07-03
BR9909995B1 (pt) 2010-07-13
DE69927803D1 (de) 2006-03-02
NZ507639A (en) 2004-01-30
PL195000B1 (pl) 2007-07-31
EP1073656A1 (de) 2001-02-07
ID27530A (id) 2001-04-12
SA99200065A (ar) 2005-12-03
BR9909996A (pt) 2000-12-26
TR200102612T2 (tr) 2002-06-21
HK1036981A1 (en) 2002-01-25
JP3883383B2 (ja) 2007-02-21
TR200102728T2 (tr) 2002-06-21
TWI250159B (en) 2006-03-01
EP1073656B1 (de) 2005-10-19
SA99200065B1 (ar) 2006-11-07
WO1999055705A1 (en) 1999-11-04
HUP0102313A2 (hu) 2001-12-28
EP1491543B1 (de) 2007-09-05
IL139200A (en) 2010-04-29
SE9801526D0 (sv) 1998-04-29
ZA200005797B (en) 2002-01-18
TR200003149T2 (tr) 2001-03-21
CZ293977B6 (cs) 2004-09-15
TW490466B (en) 2002-06-11
KR100595805B1 (ko) 2006-07-03
HUP0102425A3 (en) 2002-12-28
DE69928792D1 (de) 2006-01-12
HK1036984A1 (en) 2002-01-25
EE200000664A (et) 2002-04-15
EP1491542B1 (de) 2007-09-05
HUP0102425A2 (hu) 2001-11-28
EP1073657A1 (de) 2001-02-07
AR015768A1 (es) 2001-05-16
EP1491543A1 (de) 2004-12-29
NO20005450L (no) 2000-12-22
EP1073657B1 (de) 2005-12-07
DE69937076T2 (de) 2008-05-29
CA2329922C (en) 2006-04-11
NO318203B1 (no) 2005-02-14
CN1306533A (zh) 2001-08-01
HK1033457A1 (en) 2001-08-31
RU2235725C2 (ru) 2004-09-10
KR20050121760A (ko) 2005-12-27
NO20005451D0 (no) 2000-10-27
ATE312101T1 (de) 2005-12-15
CN1174980C (zh) 2004-11-10
AU769108B2 (en) 2004-01-15

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