HRP20020025A2 - Mono- and disubstituted 3-propyl gamma-aminobutyric acids - Google Patents

Mono- and disubstituted 3-propyl gamma-aminobutyric acids Download PDF

Info

Publication number: HRP20020025A2
Authority: HR; Croatia
Prior art keywords: aminomethyl; methyl; acid; hexanoic acid; phenoxy
Prior art date: 1999-06-10

Application number

HR20020025A

Other languages

English (en)

Croatian (hr)

Inventor

Thomas Richard Belliotti

Justin Stephen Bryans

Ihoezo Victor Ekhato

Augustine Tobi Osuma

Robert Michael Schelkun

Jacob Bradley Schwarz

Andrew John Thorpe

Lawrence David Wise

David Juergen Wustrow

Po-Wai Yuen

Original Assignee

Warner Lambert Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-10

Filing date

2000-05-31

Publication date

2003-12-31

2000-05-31 Application filed by Warner Lambert Co filed Critical Warner Lambert Co

2003-12-31 Publication of HRP20020025A2 publication Critical patent/HRP20020025A2/hr

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
- C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/20—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C229/32—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings other than six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Psychiatry (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Anesthesiology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

HR20020025A 1999-06-10 2000-05-31 Mono- and disubstituted 3-propyl gamma-aminobutyric acids HRP20020025A2 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US13848599P	1999-06-10	1999-06-10

Publications (1)

Publication Number	Publication Date
HRP20020025A2 true HRP20020025A2 (en)	2003-12-31

Family

ID=22482232

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR20020025A HRP20020025A2 (en)	1999-06-10	2000-05-31	Mono- and disubstituted 3-propyl gamma-aminobutyric acids

Country Status (43)

Country	Link
EP (1)	EP1192125B9 (es)
JP (1)	JP3904452B2 (es)
KR (1)	KR100694735B1 (es)
CN (2)	CN1196671C (es)
AP (1)	AP1397A (es)
AR (1)	AR033335A1 (es)
AT (1)	ATE419231T1 (es)
AU (1)	AU776723C (es)
BG (1)	BG65561B1 (es)
BR (1)	BR0011727A (es)
CA (2)	CA2374755C (es)
CO (1)	CO5200791A1 (es)
CR (1)	CR6529A (es)
CU (1)	CU23101A3 (es)
CY (1)	CY1108827T1 (es)
CZ (2)	CZ301608B6 (es)
DE (1)	DE60041256D1 (es)
DK (1)	DK1192125T3 (es)
DZ (1)	DZ3253A1 (es)
EA (1)	EA004398B1 (es)
EE (1)	EE200100672A (es)
ES (1)	ES2317839T3 (es)
GE (1)	GEP20074142B (es)
HK (1)	HK1046401B (es)
HR (1)	HRP20020025A2 (es)
HU (1)	HUP0201601A3 (es)
IL (2)	IL146969A0 (es)
IS (1)	IS6181A (es)
MA (1)	MA26804A1 (es)
ME (1)	MEP44808A (es)
MX (1)	MXPA01012319A (es)
NO (2)	NO327746B1 (es)
NZ (1)	NZ515668A (es)
OA (1)	OA11962A (es)
PE (1)	PE20010285A1 (es)
PT (1)	PT1192125E (es)
RS (2)	RS20090257A (es)
SI (1)	SI1192125T1 (es)
SK (2)	SK287247B6 (es)
TR (1)	TR200103587T2 (es)
UA (1)	UA72519C2 (es)
WO (1)	WO2000076958A2 (es)
ZA (1)	ZA200109711B (es)

Families Citing this family (28)

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US7164034B2 (en)	1999-06-10	2007-01-16	Pfizer Inc.	Alpha2delta ligands for fibromyalgia and other disorders
US6620829B2 (en) *	2000-10-17	2003-09-16	Warner-Lambert Company	Method of treating noninflammatory cartilage damage
US8048917B2 (en)	2005-04-06	2011-11-01	Xenoport, Inc.	Prodrugs of GABA analogs, compositions and uses thereof
KR20070108282A (ko) *	2001-06-11	2007-11-08	제노포트 인코포레이티드	감소된 독성을 가진 ｇａｂａ 유사체 프로드러그의 구강투여용 투여 형태물
ITMI20011308A1 (it)	2001-06-21	2002-12-21	Nicox Sa	Farmaci per il dolore cronico
MXPA04004105A (es)	2002-01-31	2004-11-29	Warner Lambert Co	Metodo de tratamiento de tinnitus.
NI200300043A (es) *	2002-03-28	2003-11-05	Warner Lambert Co	AMINOACIDOS CON AFINIDAD POR LA PROTEINA a2DELTA.
US20030225149A1 (en) *	2002-04-30	2003-12-04	Blazecka Peter G.	Process for preparing highly functionalized gamma-butyrolactams and gamma-amino acids
US7071339B2 (en)	2002-08-29	2006-07-04	Warner Lambert Company Llc	Process for preparing functionalized γ-butyrolactones from mucohalic acid
CA2451267A1 (en)	2002-12-13	2004-06-13	Warner-Lambert Company Llc	Pharmaceutical uses for alpha2delta ligands
AU2003303040B2 (en)	2002-12-13	2009-04-23	Warner-Lambert Company Llc	Pregabalin derivatives for the treatment of fibromyalgia and other disorders
ATE465725T1 (de)	2002-12-13	2010-05-15	Warner Lambert Co	Alpha-2-delta-ligand zur behandlung vonsymptomen der unteren harnwege
WO2004054565A1 (en) *	2002-12-13	2004-07-01	Warner-Lambert Company Llc	Pregabalin and derivates thereof for the treatment of fibromyalgia and other related disorders
ITMI20022658A1 (it)	2002-12-17	2004-06-18	Nicox Sa	Farmaci per il dolore cronico.
EP1680125A1 (en) *	2003-07-02	2006-07-19	Warner-Lambert Company LLC	Combination of an allosteric inhibitor of matrix metalloproteinase-13 and a ligand to an alpha-2-delta receptor
WO2005025675A1 (en)	2003-09-12	2005-03-24	Pfizer Limited	Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline re-uptake inhibitors
MXPA06003396A (es)	2003-09-25	2006-06-08	Warner Lambert Co	Profarmacos de aminoacidos con afinidad por la proteina a 2d.
JP4001349B2 (ja) *	2003-09-25	2007-10-31	ワーナー−ランバートカンパニーリミテッドライアビリティーカンパニー	α２δ−タンパク質に親和性を有するアミノ酸
WO2006043171A2 (en) *	2004-10-23	2006-04-27	Warner-Lambert Company Llc	Methods of using alpha2delta-1 selective compounds
CN101263113B (zh) *	2005-09-15	2012-06-13	Ucb医药有限公司	4-取代的-吡咯烷-2-酮及其用途
US20070141684A1 (en) *	2005-12-21	2007-06-21	Pfizer Inc	Preparation of gamma-amino acids having affinity for the alpha-2-delta protein
AR061728A1 (es) *	2006-06-30	2008-09-17	Pfizer Prod Inc	Composicion para tratamiento usando compuestos selectivos alfa-2-delta-1
ATE511860T1 (de)	2006-12-22	2011-06-15	Recordati Ireland Ltd	Kombinationstherapie für erkrankungen der unteren harnwege mit 2 liganden und nsar
WO2009136375A1 (en) *	2008-05-08	2009-11-12	Pfizer Inc	Treatment of interstitial cystitis
ES2758554T3 (es)	2009-12-08	2020-05-05	Univ Case Western Reserve	Aminoácidos gama para tratamiento de trastornos oculares
CN101914031B (zh) *	2010-07-30	2013-08-28	中国广州分析测试中心	普瑞巴林衍生物及其应用
SG11201803099SA (en) *	2015-10-23	2018-05-30	Navitor Pharm Inc	Modulators of sestrin-gator2 interaction and uses thereof
JP7644002B2 (ja)	2018-10-24	2025-03-11	ナビターファーマシューティカルズ，インコーポレイテッド	多形化合物およびその使用

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DE2460891C2 (de) *	1974-12-21	1982-09-23	Gödecke AG, 1000 Berlin	1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US4087544A (en) *	1974-12-21	1978-05-02	Warner-Lambert Company	Treatment of cranial dysfunctions using novel cyclic amino acids
AU9137091A (en) *	1990-11-27	1992-06-25	Northwestern University	Gaba and l-glutamic acid analogs for antiseizure treatment
US6197819B1 (en) *	1990-11-27	2001-03-06	Northwestern University	Gamma amino butyric acid analogs and optical isomers
HU222776B1 (hu) *	1992-05-20	2003-10-28	Northwestern University	(S)-(+)-4-amino-3-(2-metil-propil)-butánsav előállításának új hexánsav- és butándisav-származék köztitermékei és ezek előállítása
US5637767A (en) *	1995-06-07	1997-06-10	Warner-Lambert Company	Method of making (S)-3-(aminomethyl)-5-methylhexanoic acid
ES2200184T7 (es) *	1996-07-24	2015-02-10	Warner-Lambert Company Llc	Isobutilgaba y sus derivados para el tratamiento del dolor
CA2263663C (en) *	1996-10-23	2006-05-30	Justin Stephen Bryans	Substituted gamma aminobutyric acids as pharmaceutical agents
NZ503651A (en) *	1997-10-27	2002-09-27	Warner Lambert Co	Cyclic amino acids and derivatives thereof useful as pharmaceutical agents

2000
- 2000-05-31 OA OA1200100326A patent/OA11962A/en unknown
- 2000-05-31 AP APAP/P/2002/002388A patent/AP1397A/en active
- 2000-05-31 HK HK02107862.8A patent/HK1046401B/zh not_active IP Right Cessation
- 2000-05-31 IL IL14696900A patent/IL146969A0/xx active IP Right Grant
- 2000-05-31 SK SK1764-2001A patent/SK287247B6/sk not_active IP Right Cessation
- 2000-05-31 EE EEP200100672A patent/EE200100672A/xx unknown
- 2000-05-31 CN CNB00808730XA patent/CN1196671C/zh not_active Expired - Fee Related
- 2000-05-31 BR BR0011727-7A patent/BR0011727A/pt not_active IP Right Cessation
- 2000-05-31 CN CNB2005100037011A patent/CN1310872C/zh not_active Expired - Fee Related
- 2000-05-31 CZ CZ20080760A patent/CZ301608B6/cs not_active IP Right Cessation
- 2000-05-31 PT PT00938022T patent/PT1192125E/pt unknown
- 2000-05-31 HR HR20020025A patent/HRP20020025A2/hr not_active Application Discontinuation
- 2000-05-31 SK SK5045-2009A patent/SK287399B6/sk not_active IP Right Cessation
- 2000-05-31 DZ DZ003253A patent/DZ3253A1/fr active
- 2000-05-31 ES ES00938022T patent/ES2317839T3/es not_active Expired - Lifetime
- 2000-05-31 AT AT00938022T patent/ATE419231T1/de not_active IP Right Cessation
- 2000-05-31 KR KR1020017015841A patent/KR100694735B1/ko not_active Expired - Fee Related
- 2000-05-31 AU AU53119/00A patent/AU776723C/en not_active Ceased
- 2000-05-31 GE GE4667A patent/GEP20074142B/en unknown
- 2000-05-31 HU HU0201601A patent/HUP0201601A3/hu unknown
- 2000-05-31 SI SI200031015T patent/SI1192125T1/sl unknown
- 2000-05-31 UA UA2001128283A patent/UA72519C2/uk unknown
- 2000-05-31 JP JP2001503818A patent/JP3904452B2/ja not_active Expired - Fee Related
- 2000-05-31 CZ CZ20014285A patent/CZ300834B6/cs not_active IP Right Cessation
- 2000-05-31 WO PCT/US2000/015070 patent/WO2000076958A2/en active Application Filing
- 2000-05-31 CA CA2374755A patent/CA2374755C/en not_active Expired - Fee Related
- 2000-05-31 MX MXPA01012319A patent/MXPA01012319A/es active IP Right Grant
- 2000-05-31 ME MEP-448/08A patent/MEP44808A/xx unknown
- 2000-05-31 CA CA2689997A patent/CA2689997A1/en not_active Abandoned
- 2000-05-31 DE DE60041256T patent/DE60041256D1/de not_active Expired - Lifetime
- 2000-05-31 RS RSP-2009/0257A patent/RS20090257A/sr unknown
- 2000-05-31 DK DK00938022T patent/DK1192125T3/da active
- 2000-05-31 TR TR2001/03587T patent/TR200103587T2/xx unknown
- 2000-05-31 EA EA200101134A patent/EA004398B1/ru not_active IP Right Cessation
- 2000-05-31 NZ NZ515668A patent/NZ515668A/xx not_active IP Right Cessation
- 2000-05-31 RS YUP-870/01A patent/RS50352B/sr unknown
- 2000-05-31 EP EP00938022A patent/EP1192125B9/en not_active Expired - Lifetime
- 2000-06-07 AR ARP000102808A patent/AR033335A1/es active IP Right Grant
- 2000-06-09 CO CO00043067A patent/CO5200791A1/es not_active Application Discontinuation
- 2000-06-09 PE PE2000000577A patent/PE20010285A1/es not_active Application Discontinuation
2001
- 2001-11-26 ZA ZA200109711A patent/ZA200109711B/en unknown
- 2001-11-28 IS IS6181A patent/IS6181A/is unknown
- 2001-12-05 NO NO20015949A patent/NO327746B1/no not_active IP Right Cessation
- 2001-12-06 IL IL146969A patent/IL146969A/en not_active IP Right Cessation
- 2001-12-06 CU CU20010291A patent/CU23101A3/es not_active IP Right Cessation
- 2001-12-07 CR CR6529A patent/CR6529A/es not_active Application Discontinuation
2002
- 2002-01-02 MA MA26462A patent/MA26804A1/fr unknown
- 2002-01-09 BG BG106292A patent/BG65561B1/bg unknown
2009
- 2009-02-26 CY CY20091100228T patent/CY1108827T1/el unknown
- 2009-03-13 NO NO20091094A patent/NO20091094L/no not_active Application Discontinuation

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PT1192125E (pt)	2009-03-05
JP2003502308A (ja)	2003-01-21
CN1196671C (zh)	2005-04-13
CA2374755A1 (en)	2000-12-21
UA72519C2 (en)	2005-03-15
ES2317839T3 (es)	2009-05-01
BG65561B1 (bg)	2008-12-30
CA2689997A1 (en)	2000-12-21
WO2000076958A2 (en)	2000-12-21
PL352431A1 (en)	2003-08-25
SK287247B6 (sk)	2010-04-07
AU5311900A (en)	2001-01-02
JP3904452B2 (ja)	2007-04-11
CO5200791A1 (es)	2002-09-27
CN1660779A (zh)	2005-08-31
AU776723C (en)	2005-06-02
IS6181A (is)	2001-11-28
CA2374755C (en)	2010-03-30
YU87001A (sh)	2004-07-15
WO2000076958A3 (en)	2001-04-12
TR200103587T2 (tr)	2002-04-22
MA26804A1 (fr)	2004-12-20
CZ20014285A3 (cs)	2002-07-17
KR20020009631A (ko)	2002-02-01
RS50352B (sr)	2009-11-10
IL146969A (en)	2008-03-20
CU23101A3 (es)	2005-12-20
NO20091094L (no)	2001-12-05
EP1192125A2 (en)	2002-04-03
NO327746B1 (no)	2009-09-14
NO20015949D0 (no)	2001-12-05
HUP0201601A3 (en)	2002-11-28
KR100694735B1 (ko)	2007-03-14
HK1046401B (zh)	2005-12-02
AU776723B2 (en)	2004-09-16
ATE419231T1 (de)	2009-01-15
HK1046401A1 (en)	2003-01-10
AP1397A (en)	2005-04-19
SK17642001A3 (sk)	2002-10-08
MEP44808A (en)	2011-02-10
PE20010285A1 (es)	2001-03-22
IL146969A0 (en)	2002-08-14
NO20015949L (no)	2001-12-05
DE60041256D1 (de)	2009-02-12
DZ3253A1 (fr)	2000-12-21
AR033335A1 (es)	2003-12-17
CY1108827T1 (el)	2014-04-09
GEP20074142B (en)	2007-07-10
NZ515668A (en)	2004-02-27
OA11962A (en)	2006-04-17
EA004398B1 (ru)	2004-04-29
BR0011727A (pt)	2002-03-05
EP1192125B1 (en)	2008-12-31
EP1192125B9 (en)	2009-09-16
CN1355784A (zh)	2002-06-26
SK287399B6 (sk)	2010-08-09
MXPA01012319A (es)	2002-07-22
DK1192125T3 (da)	2009-02-16
EA200101134A1 (ru)	2002-06-27
CZ300834B6 (cs)	2009-08-19
HUP0201601A2 (en)	2002-10-28
RS20090257A (en)	2010-03-02
SI1192125T1 (sl)	2009-04-30
HK1076626A1 (en)	2006-01-20
CN1310872C (zh)	2007-04-18
BG106292A (en)	2002-05-31
EE200100672A (et)	2003-02-17
ZA200109711B (en)	2003-03-20
AP2002002388A0 (en)	2002-03-31
CZ301608B6 (cs)	2010-04-28
CR6529A (es)	2003-11-25

Publication	Publication Date	Title
HRP20020025A2 (en)	2003-12-31	Mono- and disubstituted 3-propyl gamma-aminobutyric acids
US6642398B2 (en)	2003-11-04	Mono-and disubstituted 3-propyl gamma-aminobutyric acids
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US7381747B2 (en)	2008-06-03	Alpha 2 delta ligands for post-traumatic stress disorder
PL209750B1 (pl)	2011-10-31	Pochodne aminokwasów, środek farmaceutyczny i zastosowanie pochodnych aminokwasów
MXPA04004105A (es)	2004-11-29	Metodo de tratamiento de tinnitus.
AU2003303040B2 (en)	2009-04-23	Pregabalin derivatives for the treatment of fibromyalgia and other disorders
EP1840117A1 (en)	2007-10-03	Mono- and disubstituted 3-propyl gamma-aminobutyric acids
PL203443B1 (pl)	2009-10-30	Monopodstawiony kwas 3-propylo- ?-aminomas lowy, kompozycja farmaceutyczna zawieraj aca ten zwi azek i zastosowanie
OA12543A (en)	2006-06-05	Mono-and disubstituted 3-propyl gamma-aminobutyricacids.
OA12897A (en)	2006-10-13	Mono-and disubstituted 3-propyl gamma-aminobutyricacids.

Legal Events

Date	Code	Title	Description
2003-12-31	A1OB	Publication of a patent application
2004-05-05	ARAI	Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
2008-06-24	PNAN	Change of the applicant name, address/residence	Owner name: WARNER-LAMBERT COMPANY LLC, US
2010-09-24	ODBC	Application rejected