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MA26804A1 - Acides 3-propyl-gamma-aminobutyriques mono- et disubstitues. - Google Patents

Acides 3-propyl-gamma-aminobutyriques mono- et disubstitues.

Info

Publication number
MA26804A1
MA26804A1 MA26462A MA26462A MA26804A1 MA 26804 A1 MA26804 A1 MA 26804A1 MA 26462 A MA26462 A MA 26462A MA 26462 A MA26462 A MA 26462A MA 26804 A1 MA26804 A1 MA 26804A1
Authority
MA
Morocco
Prior art keywords
disubstituted
gamma
mono
propyl
aminobutyric acids
Prior art date
Application number
MA26462A
Other languages
English (en)
Inventor
Justin Stephen Bryans
Ihoezo Victor Ekhato
Robert Michael Schelkun
Jacob Bradley Schwarz
Lawrence David Wise
David Juergen Wustrow
Thomas Richard Belliotti
Augustine Tobi Osuma
Andrew John Thorpe
Po-Wai Yuen
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of MA26804A1 publication Critical patent/MA26804A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/10—Antiepileptics; Anticonvulsants for petit-mal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/20—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/30—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and unsaturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/32—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/04—Systems containing only non-condensed rings with a four-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
MA26462A 1999-06-10 2002-01-02 Acides 3-propyl-gamma-aminobutyriques mono- et disubstitues. MA26804A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13848599P 1999-06-10 1999-06-10

Publications (1)

Publication Number Publication Date
MA26804A1 true MA26804A1 (fr) 2004-12-20

Family

ID=22482232

Family Applications (1)

Application Number Title Priority Date Filing Date
MA26462A MA26804A1 (fr) 1999-06-10 2002-01-02 Acides 3-propyl-gamma-aminobutyriques mono- et disubstitues.

Country Status (43)

Country Link
EP (1) EP1192125B9 (fr)
JP (1) JP3904452B2 (fr)
KR (1) KR100694735B1 (fr)
CN (2) CN1310872C (fr)
AP (1) AP1397A (fr)
AR (1) AR033335A1 (fr)
AT (1) ATE419231T1 (fr)
AU (1) AU776723C (fr)
BG (1) BG65561B1 (fr)
BR (1) BR0011727A (fr)
CA (2) CA2689997A1 (fr)
CO (1) CO5200791A1 (fr)
CR (1) CR6529A (fr)
CU (1) CU23101A3 (fr)
CY (1) CY1108827T1 (fr)
CZ (2) CZ301608B6 (fr)
DE (1) DE60041256D1 (fr)
DK (1) DK1192125T3 (fr)
DZ (1) DZ3253A1 (fr)
EA (1) EA004398B1 (fr)
EE (1) EE200100672A (fr)
ES (1) ES2317839T3 (fr)
GE (1) GEP20074142B (fr)
HK (2) HK1046401B (fr)
HR (1) HRP20020025A2 (fr)
HU (1) HUP0201601A3 (fr)
IL (2) IL146969A0 (fr)
IS (1) IS6181A (fr)
MA (1) MA26804A1 (fr)
ME (1) MEP44808A (fr)
MX (1) MXPA01012319A (fr)
NO (2) NO327746B1 (fr)
NZ (1) NZ515668A (fr)
OA (1) OA11962A (fr)
PE (1) PE20010285A1 (fr)
PT (1) PT1192125E (fr)
RS (2) RS20090257A (fr)
SI (1) SI1192125T1 (fr)
SK (2) SK287247B6 (fr)
TR (1) TR200103587T2 (fr)
UA (1) UA72519C2 (fr)
WO (1) WO2000076958A2 (fr)
ZA (1) ZA200109711B (fr)

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US7164034B2 (en) 1999-06-10 2007-01-16 Pfizer Inc. Alpha2delta ligands for fibromyalgia and other disorders
US6620829B2 (en) 2000-10-17 2003-09-16 Warner-Lambert Company Method of treating noninflammatory cartilage damage
HUP0400183A2 (hu) * 2001-06-11 2004-07-28 Xenoport Inc. Gaba-analóg prodrugok csökkentett toxicitású orális dózisformái
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
ITMI20011308A1 (it) 2001-06-21 2002-12-21 Nicox Sa Farmaci per il dolore cronico
CN1625393A (zh) 2002-01-31 2005-06-08 沃纳-兰伯特公司 治疗耳鸣的α2δ配体
NI200300043A (es) * 2002-03-28 2003-11-05 Warner Lambert Co AMINOACIDOS CON AFINIDAD POR LA PROTEINA a2DELTA.
US20030225149A1 (en) 2002-04-30 2003-12-04 Blazecka Peter G. Process for preparing highly functionalized gamma-butyrolactams and gamma-amino acids
US7071339B2 (en) 2002-08-29 2006-07-04 Warner Lambert Company Llc Process for preparing functionalized γ-butyrolactones from mucohalic acid
EP1572188A1 (fr) 2002-12-13 2005-09-14 Warner-Lambert Company LLC Derives de pregabalin pour le traitement de la fibromyalgie et d'autres troubles
CA2451267A1 (fr) 2002-12-13 2004-06-13 Warner-Lambert Company Llc Utilisations pharmaceutiques de ligands alpha2delta
DE60332387D1 (de) 2002-12-13 2010-06-10 Warner Lambert Co Alpha-2-delta-ligand zur behandlung vonsymptomen der unteren harnwege
JP2006511604A (ja) * 2002-12-13 2006-04-06 ワーナー−ランバート カンパニー リミティド ライアビリティー カンパニー 線維筋痛症及び関連する他の障害の治療のためのプレガバリン及びその誘導体
ITMI20022658A1 (it) 2002-12-17 2004-06-18 Nicox Sa Farmaci per il dolore cronico.
WO2005002585A1 (fr) * 2003-07-02 2005-01-13 Warner-Lambert Company Llc Combinaison d'un inhibiteur allosterique de la metalloproteinase-13 matricielle et d'un ligand au recepteur alpha-2-delta
RU2320369C2 (ru) 2003-09-12 2008-03-27 Пфайзер Инк. Комбинации, содержащие альфа-2-дельта лиганды и ингибиторы обратного захвата серотонина/норадреналина
EA200600467A1 (ru) * 2003-09-25 2006-08-25 Уорнер-Ламберт Компани Ллс АМИНОКИСЛОТЫ СО СРОДСТВОМ К α2δ-БЕЛКУ
JP2007506729A (ja) 2003-09-25 2007-03-22 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー α２δタンパク質に親和性を有するアミノ酸のプロドラッグ
WO2006043171A2 (fr) * 2004-10-23 2006-04-27 Warner-Lambert Company Llc Methodes d'utilisation de compositions selectives de alpha2delta-1
WO2007031263A1 (fr) * 2005-09-15 2007-03-22 Ucb Pharma, S.A. Pyrrolidine-2-ones 4-substituees et leur utilisation
US20070141684A1 (en) * 2005-12-21 2007-06-21 Pfizer Inc Preparation of gamma-amino acids having affinity for the alpha-2-delta protein
AR061728A1 (es) * 2006-06-30 2008-09-17 Pfizer Prod Inc Composicion para tratamiento usando compuestos selectivos alfa-2-delta-1
EA017171B1 (ru) 2006-12-22 2012-10-30 Рекордати Айерленд Лимитед КОМБИНИРОВАННАЯ ТЕРАПИЯ ЗАБОЛЕВАНИЙ НИЖНИХ МОЧЕВЫВОДЯЩИХ ПУТЕЙ С ИСПОЛЬЗОВАНИЕМ ЛИГАНДОВ αδ И НЕСТЕРОИДНЫХ ПРОТИВОВОСПАЛИТЕЛЬНЫХ ПРЕПАРАТОВ (НПВП)
WO2009136375A1 (fr) * 2008-05-08 2009-11-12 Pfizer Inc Traitement de la cystite interstitielle
EP2509596B1 (fr) 2009-12-08 2019-08-28 Case Western Reserve University Gamma acides aminés pour le traitement de troubles oculaires
CN101914031B (zh) * 2010-07-30 2013-08-28 中国广州分析测试中心 普瑞巴林衍生物及其应用
RS64114B1 (sr) * 2015-10-23 2023-04-28 Navitor Pharm Inc Modulatori interakcije sestrin-gator2 i nјihova upotreba
CN113164414A (zh) 2018-10-24 2021-07-23 纳维托制药有限公司 多晶型化合物和其用途

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US4087544A (en) * 1974-12-21 1978-05-02 Warner-Lambert Company Treatment of cranial dysfunctions using novel cyclic amino acids
AU9137091A (en) * 1990-11-27 1992-06-25 Northwestern University Gaba and l-glutamic acid analogs for antiseizure treatment
US6197819B1 (en) * 1990-11-27 2001-03-06 Northwestern University Gamma amino butyric acid analogs and optical isomers
RU94046105A (ru) * 1992-05-20 1997-06-20 Нортвестерн Юниверсити (Us) АНАЛОГИ γ -АМИНОМАСЛЯНОЙ КИСЛОТЫ И L-ГЛУТАМИНОВОЙ КИСЛОТЫ И СПОСОБЫ ИХ ПОЛУЧЕНИЯ
US5637767A (en) * 1995-06-07 1997-06-10 Warner-Lambert Company Method of making (S)-3-(aminomethyl)-5-methylhexanoic acid
KR100491282B1 (ko) * 1996-07-24 2005-05-24 워너-램버트 캄파니 엘엘씨 통증 치료용 이소부틸가바 및 그의 유도체
ATE361909T1 (de) * 1996-10-23 2007-06-15 Warner Lambert Co Substituierte gamma-aminobuttersäurederivate als arzneimittel
PL199794B1 (pl) * 1997-10-27 2008-10-31 Warner Lambert Co Związki pośrednie do wytwarzania pochodnych cyklicznych aminokwasów

Also Published As

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HK1076626A1 (en) 2006-01-20
EP1192125B9 (fr) 2009-09-16
HK1046401A1 (en) 2003-01-10
EP1192125B1 (fr) 2008-12-31
YU87001A (sh) 2004-07-15
IS6181A (is) 2001-11-28
CZ301608B6 (cs) 2010-04-28
IL146969A (en) 2008-03-20
ATE419231T1 (de) 2009-01-15
CO5200791A1 (es) 2002-09-27
GEP20074142B (en) 2007-07-10
CU23101A3 (es) 2005-12-20
NZ515668A (en) 2004-02-27
EA004398B1 (ru) 2004-04-29
CZ300834B6 (cs) 2009-08-19
CZ20014285A3 (cs) 2002-07-17
CR6529A (es) 2003-11-25
JP3904452B2 (ja) 2007-04-11
PE20010285A1 (es) 2001-03-22
AP1397A (en) 2005-04-19
AU5311900A (en) 2001-01-02
CN1196671C (zh) 2005-04-13
CN1310872C (zh) 2007-04-18
DE60041256D1 (de) 2009-02-12
PL352431A1 (en) 2003-08-25
EP1192125A2 (fr) 2002-04-03
CY1108827T1 (el) 2014-04-09
HUP0201601A2 (en) 2002-10-28
DZ3253A1 (fr) 2000-12-21
KR20020009631A (ko) 2002-02-01
ES2317839T3 (es) 2009-05-01
IL146969A0 (en) 2002-08-14
KR100694735B1 (ko) 2007-03-14
SK17642001A3 (sk) 2002-10-08
NO20015949L (no) 2001-12-05
SI1192125T1 (sl) 2009-04-30
MEP44808A (en) 2011-02-10
HUP0201601A3 (en) 2002-11-28
WO2000076958A2 (fr) 2000-12-21
RS50352B (sr) 2009-11-10
DK1192125T3 (da) 2009-02-16
AP2002002388A0 (en) 2002-03-31
CA2374755C (fr) 2010-03-30
ZA200109711B (en) 2003-03-20
EA200101134A1 (ru) 2002-06-27
CN1355784A (zh) 2002-06-26
BG65561B1 (bg) 2008-12-30
BG106292A (en) 2002-05-31
HK1046401B (zh) 2005-12-02
AR033335A1 (es) 2003-12-17
EE200100672A (et) 2003-02-17
AU776723C (en) 2005-06-02
HRP20020025A2 (en) 2003-12-31
SK287399B6 (sk) 2010-08-09
JP2003502308A (ja) 2003-01-21
UA72519C2 (en) 2005-03-15
SK287247B6 (sk) 2010-04-07
OA11962A (en) 2006-04-17
CA2374755A1 (fr) 2000-12-21
MXPA01012319A (es) 2002-07-22
AU776723B2 (en) 2004-09-16
RS20090257A (en) 2010-03-02
NO20015949D0 (no) 2001-12-05
PT1192125E (pt) 2009-03-05
WO2000076958A3 (fr) 2001-04-12
CA2689997A1 (fr) 2000-12-21
NO20091094L (no) 2001-12-05
TR200103587T2 (tr) 2002-04-22
BR0011727A (pt) 2002-03-05
CN1660779A (zh) 2005-08-31
NO327746B1 (no) 2009-09-14

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