HN1999000072A - Preparaciones farmaceuticas estabilizadas de gaba pentina y proceso para prepararla. - Google Patents
Preparaciones farmaceuticas estabilizadas de gaba pentina y proceso para prepararla.Info
- Publication number
- HN1999000072A HN1999000072A HN1999000072A HN1999000072A HN1999000072A HN 1999000072 A HN1999000072 A HN 1999000072A HN 1999000072 A HN1999000072 A HN 1999000072A HN 1999000072 A HN1999000072 A HN 1999000072A HN 1999000072 A HN1999000072 A HN 1999000072A
- Authority
- HN
- Honduras
- Prior art keywords
- pharmaceutical preparations
- pentina
- gaba
- preparing
- stabilized pharmaceutical
- Prior art date
Links
- UGJMXCAKCUNAIE-UHFFFAOYSA-N Gabapentin Chemical compound OC(=O)CC1(CN)CCCCC1 UGJMXCAKCUNAIE-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000825 pharmaceutical preparation Substances 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 229960002870 gabapentin Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
- A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polymerisation Methods In General (AREA)
Abstract
LA PRESENTE INVENCION SE REFIERE A PREPARACIONES FARMACEUTICAS ESTABILIZADAS DE GABAPENTINA Y PROCESO PARA PREPARARLA.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13311398 | 1998-05-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
HN1999000072A true HN1999000072A (es) | 2000-06-05 |
Family
ID=15097118
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HN1999000072A HN1999000072A (es) | 1998-05-15 | 1999-05-14 | Preparaciones farmaceuticas estabilizadas de gaba pentina y proceso para prepararla. |
Country Status (36)
Country | Link |
---|---|
US (1) | US7309719B1 (es) |
EP (1) | EP1077692B1 (es) |
JP (1) | JP4612923B2 (es) |
KR (1) | KR100602047B1 (es) |
CN (1) | CN1303991C (es) |
AR (1) | AR020323A1 (es) |
AT (1) | ATE271864T1 (es) |
AU (1) | AU768277B2 (es) |
BR (1) | BR9910508B1 (es) |
CA (1) | CA2327285C (es) |
CO (1) | CO5021224A1 (es) |
CR (1) | CR6026A (es) |
CU (1) | CU23253B7 (es) |
DE (1) | DE69918977T2 (es) |
DK (1) | DK1077692T3 (es) |
EG (1) | EG26803A (es) |
ES (1) | ES2221385T3 (es) |
GT (1) | GT199900069A (es) |
HN (1) | HN1999000072A (es) |
HU (1) | HU228771B1 (es) |
ID (1) | ID27724A (es) |
IL (2) | IL139298A0 (es) |
IS (1) | IS2233B (es) |
MY (1) | MY157878A (es) |
NO (1) | NO328959B1 (es) |
NZ (1) | NZ508015A (es) |
PA (1) | PA8472801A1 (es) |
PE (1) | PE20000556A1 (es) |
PL (1) | PL204921B1 (es) |
PT (1) | PT1077692E (es) |
SI (1) | SI1077692T1 (es) |
SV (1) | SV1999000064A (es) |
TW (1) | TWI243054B (es) |
UY (1) | UY25512A1 (es) |
WO (1) | WO1999059573A1 (es) |
ZA (1) | ZA200006484B (es) |
Families Citing this family (39)
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ES2200184T7 (es) | 1996-07-24 | 2015-02-10 | Warner-Lambert Company Llc | Isobutilgaba y sus derivados para el tratamiento del dolor |
ATE255891T1 (de) * | 2000-06-16 | 2003-12-15 | Teva Pharma | Stabiles gabapentin, das mehr als 20 ppm chlor enthält |
YU95302A (sh) * | 2000-06-16 | 2006-05-25 | Teva Pharmaceutical Industries Ltd. | Stabilni gabapentin koji ima ph u kontrolisanom rasponu |
EP1384473A1 (en) * | 2000-06-16 | 2004-01-28 | Teva Pharmaceutical Industries Ltd. | Stable gabapentin containing more than 20 ppm of chlorine ion |
EP1430893A1 (en) * | 2000-06-16 | 2004-06-23 | Teva Pharmaceutical Industries Ltd. | Stable gabapentin containing more than 20 ppm of chloride ion |
US7056951B2 (en) | 2000-09-26 | 2006-06-06 | Mutual Pharmaceutical Co., Inc. | Stable solid dosage forms of amino acids and processes for producing same |
CA2446574C (en) * | 2001-05-25 | 2008-04-01 | Neema Mahesh Kulkarni | Liquid pharmaceutical composition |
JP2007520547A (ja) * | 2004-02-04 | 2007-07-26 | アレムビック・リミテッド | ベンラファキシン塩酸塩の徐放性コーティングされた小型錠剤 |
JP2007538080A (ja) * | 2004-05-17 | 2007-12-27 | オデッサ ファーマ,エルエルシー | α−ケト分岐鎖アミノ酸を用いた脳神経細胞内グルタミン酸レベルの低減 |
NL2000281C2 (nl) | 2005-11-02 | 2007-08-07 | Pfizer Prod Inc | Vaste farmaceutische samenstellingen die pregabaline bevatten. |
WO2007107835A2 (en) * | 2006-03-17 | 2007-09-27 | Aurobindo Pharma Limited | Stable liquid formulations of antiepileptic agents |
DE102007019071A1 (de) | 2007-04-23 | 2008-10-30 | Ratiopharm Gmbh | Stabilisierte pharmazeutische Zusammensetzung enthaltend Pregabalin |
FR2918567B1 (fr) * | 2007-07-11 | 2012-08-03 | Pf Medicament | Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine. |
JP2010043063A (ja) | 2008-05-09 | 2010-02-25 | Agency For Science Technology & Research | 川崎病の診断及び治療 |
CN102438587B (zh) | 2009-05-19 | 2015-08-19 | 神经层有限公司 | 用于多巴脱羧酶抑制剂连续施用的组合物 |
HU230031B1 (hu) | 2010-03-01 | 2015-05-28 | Egis Gyógyszergyár Nyilvánosan Működő Részvénytársaság | Pregabalint és izomaltot tartalmazó stabilizált gyógyszerkészítmény |
EP2389933A1 (en) | 2010-05-25 | 2011-11-30 | Sanovel Ilac Sanayi ve Ticaret A.S. | Controlled-Release Pregabalin Compositions |
EP2389934A1 (en) | 2010-05-25 | 2011-11-30 | Sanovel Ilac Sanayi ve Ticaret A.S. | Controlled-Release Tablet Formulations of Pregabalin |
TR201005241A1 (tr) | 2010-05-25 | 2012-01-23 | Sanovel �La� San. Ve T�C. A.�. | Kontrollü salım sağlayan pregabalin solüsyon formülasyonu. |
MX348225B (es) | 2010-11-15 | 2017-05-31 | Neuroderm Ltd | Administracion continua de levodopa, inhibidores de dopa decarboxilasa, inhibidores de catecol-o-metil transferasa y composiciones para la misma. |
EP3456315A1 (en) | 2012-06-05 | 2019-03-20 | Neuroderm Ltd | Compositions comprising apomorphine and organic acids and uses thereof |
CN103494796B (zh) * | 2013-09-30 | 2016-01-20 | 浙江华义医药有限公司 | 普瑞巴林稳定的药物组合物及其制备方法 |
EP3099288A1 (en) | 2014-01-28 | 2016-12-07 | Sun Pharmaceutical Industries Ltd | Stabilized gastroretentive tablets of pregabalin |
US10258585B2 (en) | 2014-03-13 | 2019-04-16 | Neuroderm, Ltd. | DOPA decarboxylase inhibitor compositions |
HUE064818T2 (hu) | 2014-03-13 | 2024-04-28 | Neuroderm Ltd | Dopa dekarboxiláz inhibitor készítmények |
EP2923694B1 (en) * | 2014-03-27 | 2018-11-14 | Sanovel Ilac Sanayi ve Ticaret A.S. | Oral liquid pharmaceutical solution of gabapentin |
EP2929878A1 (en) * | 2014-04-09 | 2015-10-14 | Arven Ilac Sanayi ve Ticaret A.S. | Extended release formulations of gabapentin |
EP3302425A4 (en) | 2015-05-26 | 2018-12-26 | Isa Odidi | Controlled extended release pregabalin |
JP6919119B2 (ja) * | 2017-01-23 | 2021-08-18 | 日新製薬株式会社 | 3位が置換されたγ−アミノ酪酸誘導体を含有する圧縮固形医薬組成物。 |
WO2020071546A1 (ja) | 2018-10-04 | 2020-04-09 | 株式会社 メドレックス | 非水系溶媒により安定化された製剤 |
US10792262B1 (en) | 2019-07-29 | 2020-10-06 | Saol International Limited | Stabilized formulations of 4-amino-3-substituted butanoic acid derivatives |
US11654124B2 (en) | 2019-07-29 | 2023-05-23 | Amneal Pharmaceuticals Llc | Stabilized formulations of 4-amino-3-substituted butanoic acid derivatives |
AU2020370758A1 (en) | 2019-10-25 | 2022-06-02 | Kyoto University | Preventative or therapeutic agent for tauopathy |
US11331293B1 (en) | 2020-11-17 | 2022-05-17 | Neuroderm, Ltd. | Method for treatment of Parkinson's disease |
US11844754B2 (en) | 2020-11-17 | 2023-12-19 | Neuroderm, Ltd. | Methods for treatment of Parkinson's disease |
US11213502B1 (en) | 2020-11-17 | 2022-01-04 | Neuroderm, Ltd. | Method for treatment of parkinson's disease |
CN112843015A (zh) * | 2021-04-08 | 2021-05-28 | 海南鑫开源医药科技有限公司 | 一种加巴喷丁胶囊制剂及其制备方法 |
WO2023055457A1 (en) | 2021-09-29 | 2023-04-06 | Amneal Pharmaceuticals Llc | Baclofen-containing granule formulations and reduced patient exposure to metabolite variations |
US12161612B2 (en) | 2023-04-14 | 2024-12-10 | Neuroderm, Ltd. | Methods and compositions for reducing symptoms of Parkinson's disease |
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ES2200184T7 (es) * | 1996-07-24 | 2015-02-10 | Warner-Lambert Company Llc | Isobutilgaba y sus derivados para el tratamiento del dolor |
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IT1311984B1 (it) * | 1999-03-26 | 2002-03-22 | Bioindustria Lab Italiano Medi | Procedimento per la preparzione di gabapentin. |
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KR20070108282A (ko) * | 2001-06-11 | 2007-11-08 | 제노포트 인코포레이티드 | 감소된 독성을 가진 gaba 유사체 프로드러그의 구강투여용 투여 형태물 |
-
1999
- 1999-05-10 KR KR1020007012759A patent/KR100602047B1/ko not_active Expired - Fee Related
- 1999-05-10 WO PCT/US1999/010190 patent/WO1999059573A1/en active IP Right Grant
- 1999-05-10 HU HU0102022A patent/HU228771B1/hu not_active IP Right Cessation
- 1999-05-10 ID IDW20002352A patent/ID27724A/id unknown
- 1999-05-10 SI SI9930624T patent/SI1077692T1/xx unknown
- 1999-05-10 AU AU40735/99A patent/AU768277B2/en not_active Ceased
- 1999-05-10 NZ NZ508015A patent/NZ508015A/en not_active IP Right Cessation
- 1999-05-10 EP EP99924166A patent/EP1077692B1/en not_active Expired - Lifetime
- 1999-05-10 BR BRPI9910508-0A patent/BR9910508B1/pt not_active IP Right Cessation
- 1999-05-10 IL IL13929899A patent/IL139298A0/xx unknown
- 1999-05-10 DK DK99924166T patent/DK1077692T3/da active
- 1999-05-10 PT PT99924166T patent/PT1077692E/pt unknown
- 1999-05-10 US US09/674,815 patent/US7309719B1/en not_active Expired - Fee Related
- 1999-05-10 CA CA002327285A patent/CA2327285C/en not_active Expired - Lifetime
- 1999-05-10 CN CNB998061557A patent/CN1303991C/zh not_active Expired - Fee Related
- 1999-05-10 PL PL344218A patent/PL204921B1/pl unknown
- 1999-05-10 ES ES99924166T patent/ES2221385T3/es not_active Expired - Lifetime
- 1999-05-10 AT AT99924166T patent/ATE271864T1/de active
- 1999-05-10 DE DE69918977T patent/DE69918977T2/de not_active Expired - Lifetime
- 1999-05-12 CR CR6026A patent/CR6026A/es unknown
- 1999-05-12 TW TW088107704A patent/TWI243054B/zh not_active IP Right Cessation
- 1999-05-13 MY MYPI99001901A patent/MY157878A/en unknown
- 1999-05-13 PA PA19998472801A patent/PA8472801A1/es unknown
- 1999-05-13 EG EG1999050554A patent/EG26803A/en active
- 1999-05-14 JP JP13377399A patent/JP4612923B2/ja not_active Expired - Lifetime
- 1999-05-14 AR ARP990102313A patent/AR020323A1/es active IP Right Grant
- 1999-05-14 GT GT199900069A patent/GT199900069A/es unknown
- 1999-05-14 SV SV1999000064A patent/SV1999000064A/es active IP Right Grant
- 1999-05-14 HN HN1999000072A patent/HN1999000072A/es unknown
- 1999-05-14 PE PE1999000407A patent/PE20000556A1/es not_active Application Discontinuation
- 1999-05-14 UY UY25512A patent/UY25512A1/es not_active IP Right Cessation
- 1999-05-14 CO CO99030149A patent/CO5021224A1/es unknown
-
2000
- 2000-10-16 IS IS5666A patent/IS2233B/is unknown
- 2000-10-26 IL IL139298A patent/IL139298A/en not_active IP Right Cessation
- 2000-11-09 ZA ZA200006484A patent/ZA200006484B/en unknown
- 2000-11-14 NO NO20005768A patent/NO328959B1/no not_active IP Right Cessation
- 2000-11-15 CU CU20000256A patent/CU23253B7/es unknown
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