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HK1059210A1 - 控釋羥二氫可待因酮組合物 - Google Patents

控釋羥二氫可待因酮組合物 Download PDF

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Publication number
HK1059210A1
HK1059210A1 HK04100077A HK04100077A HK1059210A1 HK 1059210 A1 HK1059210 A1 HK 1059210A1 HK 04100077 A HK04100077 A HK 04100077A HK 04100077 A HK04100077 A HK 04100077A HK 1059210 A1 HK1059210 A1 HK 1059210A1
Authority
HK
Hong Kong
Prior art keywords
oxycodone
hours
formulation
mean
dosage form
Prior art date
Application number
HK04100077A
Other languages
German (de)
English (en)
French (fr)
Other versions
HK1059210B (zh
Inventor
Oshlack Benjamin
Chasin Mark
Joseph Minogue John
Francis Kaiko Robert
Original Assignee
The Purdue Pharma Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25178688&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1059210(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by The Purdue Pharma Company filed Critical The Purdue Pharma Company
Priority claimed from HK03102581.8A external-priority patent/HK1051803B/zh
Publication of HK1059210A1 publication Critical patent/HK1059210A1/zh
Publication of HK1059210B publication Critical patent/HK1059210B/zh

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2013Organic compounds, e.g. phospholipids, fats
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/485Morphinan derivatives, e.g. morphine, codeine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5015Organic compounds, e.g. fats, sugars
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Fluid Pressure (AREA)
  • Polyethers (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK04100077.2A 1991-11-27 2003-04-09 控释羟二氢可待因酮组合物 HK1059210B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US800549 1991-11-27
US07/800,549 US5266331A (en) 1991-11-27 1991-11-27 Controlled release oxycodone compositions
HK03102581.8A HK1051803B (zh) 1991-11-27 2003-04-09 控释羟二氢可待因酮组合物

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
HK03102581.8A Addition HK1051803B (zh) 1991-11-27 2003-04-09 控释羟二氢可待因酮组合物

Related Child Applications (1)

Application Number Title Priority Date Filing Date
HK03102581.8A Division HK1051803B (zh) 1991-11-27 2003-04-09 控释羟二氢可待因酮组合物

Publications (2)

Publication Number Publication Date
HK1059210A1 true HK1059210A1 (zh) 2004-06-25
HK1059210B HK1059210B (zh) 2004-12-17

Family

ID=

Also Published As

Publication number Publication date
FI113152B (fi) 2004-03-15
FI118251B (fi) 2007-09-14
DE69233640D1 (de) 2006-08-24
HK1051803A1 (zh) 2003-08-22
NO932661L (no) 1993-09-24
EP0722730A1 (en) 1996-07-24
EP2340833A2 (en) 2011-07-06
GR3022273T3 (en) 1997-04-30
ATE360421T1 (de) 2007-05-15
ATE261726T1 (de) 2004-04-15
CZ298499B6 (cs) 2007-10-17
EP2243484A2 (en) 2010-10-27
YU49495B (sh) 2006-08-17
US5549912A (en) 1996-08-27
HUT69401A (en) 1995-09-28
DK0722730T3 (da) 2002-11-25
DE69214802D1 (de) 1996-11-28
EP2106796A2 (en) 2009-10-07
EP1502592A1 (en) 2005-02-02
PT1502592E (pt) 2007-09-17
EP1327446B1 (en) 2004-03-17
NO318890B1 (no) 2005-05-18
EP1438959B1 (en) 2007-04-25
ES2339392T3 (es) 2010-05-19
HK1058474A1 (zh) 2004-05-21
ATE261725T1 (de) 2004-04-15
NO323334B1 (no) 2007-03-26
PT1325746E (pt) 2006-11-30
US20020018810A1 (en) 2002-02-14
KR100280973B1 (ko) 2001-02-01
IL103909A (en) 1996-09-12
US20040185098A1 (en) 2004-09-23
US20060165791A1 (en) 2006-07-27
HU227514B1 (en) 2011-07-28
EP1258246A3 (en) 2003-01-08
PL172236B1 (pl) 1997-08-29
EP1502592B1 (en) 2007-06-20
US20060165792A1 (en) 2006-07-27
HU0303097D0 (en) 2003-11-28
PT1327445E (pt) 2004-07-30
DE69233328T2 (de) 2005-03-10
FI20080512L (fi) 2008-09-11
ES2186737T3 (es) 2003-05-16
US20030099704A1 (en) 2003-05-29
CZ176493A3 (en) 1994-04-13
HU0302920D0 (en) 2003-11-28
DE69233640T2 (de) 2007-06-14
FI118250B (fi) 2007-09-14
PT1810679E (pt) 2010-02-18
EP2289517B1 (en) 2014-05-07
PT722730E (pt) 2003-03-31
FI118252B (fi) 2007-09-14
DK0722730T4 (da) 2013-11-18
EP1438959A1 (en) 2004-07-21
EP0576643A1 (en) 1994-01-05
EP1774969A2 (en) 2007-04-18
JPH06507645A (ja) 1994-09-01
EP2340833A3 (en) 2012-09-12
CA2098738C (en) 1999-08-17
PT1327446E (pt) 2004-06-30
US20040096500A1 (en) 2004-05-20
HU227515B1 (en) 2011-07-28
ES2286523T3 (es) 2007-12-01
DE69233328D1 (de) 2004-04-22
RU2122411C1 (ru) 1998-11-27
CN1165307C (zh) 2004-09-08
ATE365041T1 (de) 2007-07-15
FI20070282A7 (fi) 2007-04-12
NO932661D0 (no) 1993-07-23
EP0722730B2 (en) 2013-08-07
ES2215984T3 (es) 2004-10-16
PT1258246E (pt) 2004-06-30
NO307028B3 (no) 2009-05-25
AU657027B2 (en) 1995-02-23
DK1327445T3 (da) 2004-07-26
DK1327446T3 (da) 2004-08-02
FI20080512A7 (fi) 2008-09-11
US5508042A (en) 1996-04-16
EP0576643A4 (en) 1994-03-18
EP2106797A3 (en) 2009-11-04
NO996447D0 (no) 1999-12-23
DE69233699D1 (de) 2007-08-02
HU224075B1 (hu) 2005-05-30
DE69233699T2 (de) 2008-02-28
NO20041667L (no) 1993-09-24
DK1438959T3 (da) 2007-09-17
DK1327446T4 (da) 2007-12-17
US20060099255A1 (en) 2006-05-11
EP1327446A1 (en) 2003-07-16
EP0576643B1 (en) 1996-10-23
DE69233328T3 (de) 2008-02-07
DK200000364U3 (da) 2001-03-23
NO20041662L (no) 1993-09-24
EP0722730B1 (en) 2002-10-30
EP1810679B1 (en) 2010-01-06
AU3147693A (en) 1993-06-28
DE69233691D1 (de) 2007-06-06
ATE332691T1 (de) 2006-08-15
ES2268189T3 (es) 2007-03-16
DE69233778D1 (de) 2010-02-25
EP1325746B1 (en) 2006-07-12
HU0400224D0 (en) 2004-04-28
RO115112B1 (ro) 1999-11-30
NO996447L (no) 1993-09-24
ES2096781T3 (es) 1997-03-16
MX9302968A (es) 1994-05-31
CZ286913B6 (cs) 2000-08-16
EP1810679A3 (en) 2007-10-03
FI20031890L (fi) 2003-12-22
HU0400357D0 (en) 2004-04-28
DE69233326D1 (de) 2004-04-22
HU227518B1 (en) 2011-07-28
US5266331A (en) 1993-11-30
EP2243484A3 (en) 2012-01-11
RS50056B (sr) 2008-11-28
FI116658B (fi) 2006-01-31
FI20031889L (fi) 2003-12-22
WO1993010765A1 (en) 1993-06-10
RS50054B (sr) 2008-11-28
HU226929B1 (en) 2010-03-01
ATE261727T1 (de) 2004-04-15
FI20031888L (fi) 2003-12-22
NO20041939L (no) 1993-05-27
EP1327446B2 (en) 2007-08-22
DK1810679T3 (da) 2010-02-08
DK1325746T3 (da) 2006-11-06
EP2106797A2 (en) 2009-10-07
CA2098738A1 (en) 1993-05-28
SK280295B6 (sk) 1999-11-08
PL173574B1 (pl) 1998-03-31
IL103909A0 (en) 1993-04-04
FI933330A7 (fi) 1993-07-23
JP2002370983A (ja) 2002-12-24
ATE226822T1 (de) 2002-11-15
US20060057210A1 (en) 2006-03-16
YU35893A (sh) 1997-03-07
BG97973A (bg) 1994-05-27
ES2186737T5 (es) 2014-01-17
HU9301517D0 (en) 1993-09-28
FI933330A0 (fi) 1993-07-23
ES2213720T3 (es) 2004-09-01
US20040105887A1 (en) 2004-06-03
DE69232837T3 (de) 2014-01-02
US20010008639A1 (en) 2001-07-19
DK0722730T5 (da) 2003-03-31
HK1059209A1 (zh) 2004-06-25
NO307028B1 (no) 2000-01-31
FI20031891L (fi) 2003-12-22
ES2287625T3 (es) 2007-12-16
EP1325746A1 (en) 2003-07-09
HU227516B1 (en) 2011-07-28
DE69233327T2 (de) 2005-03-10
DK1258246T3 (da) 2004-07-05
NO322378B1 (no) 2006-09-25
ES2215983T3 (es) 2004-10-16
DK0576643T3 (da) 1997-04-21
JP4016074B2 (ja) 2007-12-05
FI20070282L (fi) 2007-04-12
EP2106796A3 (en) 2009-11-04
PH31679A (en) 1999-01-18
EP1327445B1 (en) 2004-03-17
EP1810679A2 (en) 2007-07-25
HU227517B1 (en) 2011-07-28
HK1073255A1 (zh) 2005-09-30
EP1327445A1 (en) 2003-07-16
HU228058B1 (en) 2012-09-28
CN1245958C (zh) 2006-03-22
HU0401532D0 (en) 2004-09-28
NO325483B1 (no) 2008-05-13
DE69233691T2 (de) 2008-01-24
CN1087262A (zh) 1994-06-01
RS50055B (sr) 2008-11-28
ES2215984T5 (es) 2008-03-16
HU0400227D0 (en) 2004-04-28
ZA929227B (en) 1993-07-12
CZ300183B6 (cs) 2009-03-11
CZ292849B6 (cs) 2003-12-17
EP2289517A2 (en) 2011-03-02
DE69232837D1 (de) 2002-12-05
HU0400225D0 (en) 2004-04-28
DK0576643T5 (da) 2004-11-22
DE69233327D1 (de) 2004-04-22
HK1068004A1 (zh) 2005-04-22
DE69233326T2 (de) 2005-03-10
JP3375960B2 (ja) 2003-02-10
ATE454150T1 (de) 2010-01-15
NO20043264L (no) 1993-09-24
SK92293A3 (en) 1994-04-06
PT1438959E (pt) 2007-07-19
CN1364458A (zh) 2002-08-21
DE9219234U1 (de) 2001-03-29
DK1502592T3 (da) 2007-10-22
HU0400226D0 (en) 2004-04-28
BR9205498A (pt) 1994-06-07
DE69214802T2 (de) 1997-05-07
EP1258246B1 (en) 2004-03-17
ATE144418T1 (de) 1996-11-15
EP1258246A2 (en) 2002-11-20
DE69232837T2 (de) 2003-06-18
EP1774969A3 (en) 2007-10-03
EP2289517A3 (en) 2012-07-04
HU227815B1 (en) 2012-03-28
BG61753B1 (bg) 1998-05-29

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Effective date: 20121124