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FR2232320A1 - 4-Amino-uracil derivs - hypocholesterolemiant having diuretic activity - Google Patents

4-Amino-uracil derivs - hypocholesterolemiant having diuretic activity

Info

Publication number
FR2232320A1
FR2232320A1 FR7419693A FR7419693A FR2232320A1 FR 2232320 A1 FR2232320 A1 FR 2232320A1 FR 7419693 A FR7419693 A FR 7419693A FR 7419693 A FR7419693 A FR 7419693A FR 2232320 A1 FR2232320 A1 FR 2232320A1
Authority
FR
France
Prior art keywords
opt
amino
branched
unsaturated
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7419693A
Other languages
French (fr)
Other versions
FR2232320B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JOHANN A WULFING DT
Original Assignee
JOHANN A WULFING DT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JOHANN A WULFING DT filed Critical JOHANN A WULFING DT
Publication of FR2232320A1 publication Critical patent/FR2232320A1/en
Application granted granted Critical
Publication of FR2232320B1 publication Critical patent/FR2232320B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52—Two oxygen atoms
    • C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Novel title cpds. have formul: (where R1 and/or R2=H or opt. branched, opt. unsaturated =6C alkyl (opt. substd. by ether gp., hydroxy or -NR6R7); R6 and/or R7=H, opt. branched, opt. unsaturated =4C alkyl or cycloalkyl; R3=H, opt. branched, opt. unsaturated alkyl, aralkyl, aryl, cycloalkyl, halo, nitro, amino, acylamino or formyl R4, R5=H, opt. branched opt. unsaturated =6C alkyl which may contain heteroatom and may form a heterocyclic ring) including their acid addition salts.
FR7419693A 1973-06-08 1974-06-07 4-Amino-uracil derivs - hypocholesterolemiant having diuretic activity Granted FR2232320A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19732329399 DE2329399A1 (en) 1973-06-08 1973-06-08 4-ALKYL-AMINOURACILE, THE METHOD FOR MANUFACTURING IT AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS

Publications (2)

Publication Number Publication Date
FR2232320A1 true FR2232320A1 (en) 1975-01-03
FR2232320B1 FR2232320B1 (en) 1978-07-28

Family

ID=5883531

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7419693A Granted FR2232320A1 (en) 1973-06-08 1974-06-07 4-Amino-uracil derivs - hypocholesterolemiant having diuretic activity

Country Status (10)

Country Link
JP (1) JPS5052077A (en)
AT (1) AT332425B (en)
BE (1) BE816055A (en)
DD (1) DD119233A5 (en)
DE (1) DE2329399A1 (en)
FI (1) FI157974A (en)
FR (1) FR2232320A1 (en)
HU (1) HU168153B (en)
NL (1) NL7407611A (en)
SE (1) SE7407471L (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0447324A1 (en) * 1990-03-15 1991-09-18 Sanofi 2,4-Pyrimidinedione derivatives and medicines containing them
EP0967209A1 (en) * 1998-06-26 1999-12-29 Witco Vinyl Additives GmbH NH2-modified 6-aminouracils as stabilisers for halogen-containing polymers
WO2003000664A1 (en) * 2001-06-22 2003-01-03 Bayer Aktiengesellschaft Uracil derivatives and the use thereof for treating bacterial diseases

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3222914A1 (en) * 1982-06-18 1983-12-22 Beiersdorf Ag, 2000 Hamburg SUBSTITUTED 5-PHENYLTHIO-6-AMINO-PYRIMIDINONE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE, AND PREPARATIONS CONTAINING THESE COMPOUNDS
JPH0688982B2 (en) * 1988-10-29 1994-11-09 三井東圧化学株式会社 Novel pyrimidinedione derivative and antiarrhythmic agent containing the compound
US5008267A (en) * 1988-10-29 1991-04-16 Mitsui Toatsu Chemicals, Incorporated Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same
RU2449994C1 (en) * 2011-03-10 2012-05-10 Светлана Алексеевна Мещерякова 6-(4-benzylpiperazino)-1,3-dimethyluracyl dihydrochloride showing biological activity

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3147257A (en) * 1959-03-24 1964-09-01 Robugen Gmbh New substituted 4-aminouracil derivatives
GB1110734A (en) * 1966-11-10 1968-04-24 Interpharm G M B H & Co K G 9-substituted isotheophyllines
FR2073300A1 (en) * 1969-08-20 1971-10-01 Byk Gulden Lomberg Chem Fab
DE2150686A1 (en) * 1971-10-12 1973-04-19 Basf Ag 6-amino-uracil-5-carboxylic acid thioamides - inters for dyestuffs and pharmaceuticals

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3147257A (en) * 1959-03-24 1964-09-01 Robugen Gmbh New substituted 4-aminouracil derivatives
GB1110734A (en) * 1966-11-10 1968-04-24 Interpharm G M B H & Co K G 9-substituted isotheophyllines
FR2073300A1 (en) * 1969-08-20 1971-10-01 Byk Gulden Lomberg Chem Fab
DE2150686A1 (en) * 1971-10-12 1973-04-19 Basf Ag 6-amino-uracil-5-carboxylic acid thioamides - inters for dyestuffs and pharmaceuticals

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0447324A1 (en) * 1990-03-15 1991-09-18 Sanofi 2,4-Pyrimidinedione derivatives and medicines containing them
FR2659656A1 (en) * 1990-03-15 1991-09-20 Sanofi Sa 2,4-PYRIMIDINEDIONE DERIVATIVES AND MEDICAMENTS CONTAINING SAME
EP0967209A1 (en) * 1998-06-26 1999-12-29 Witco Vinyl Additives GmbH NH2-modified 6-aminouracils as stabilisers for halogen-containing polymers
WO2003000664A1 (en) * 2001-06-22 2003-01-03 Bayer Aktiengesellschaft Uracil derivatives and the use thereof for treating bacterial diseases

Also Published As

Publication number Publication date
ATA430074A (en) 1976-01-15
AT332425B (en) 1976-09-27
DD119233A5 (en) 1976-04-12
HU168153B (en) 1976-02-28
SE7407471L (en) 1974-12-09
NL7407611A (en) 1974-12-10
DE2329399A1 (en) 1975-01-02
FR2232320B1 (en) 1978-07-28
JPS5052077A (en) 1975-05-09
BE816055A (en) 1974-09-30
FI157974A (en) 1974-12-09

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Legal Events

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