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FR2172790A1 - 10-(beta amino propinyl) pheno thiazines - as diuretic, antiinflammat and anti-ulcer agents - Google Patents

10-(beta amino propinyl) pheno thiazines - as diuretic, antiinflammat and anti-ulcer agents

Info

Publication number
FR2172790A1
FR2172790A1 FR7205875A FR7205875A FR2172790A1 FR 2172790 A1 FR2172790 A1 FR 2172790A1 FR 7205875 A FR7205875 A FR 7205875A FR 7205875 A FR7205875 A FR 7205875A FR 2172790 A1 FR2172790 A1 FR 2172790A1
Authority
FR
France
Prior art keywords
antiinflammat
thiazines
propinyl
pheno
diuretic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7205875A
Other languages
French (fr)
Other versions
FR2172790B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE795667D priority Critical patent/BE795667A/en
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR7205875A priority patent/FR2172790A1/en
Priority to NL7302392A priority patent/NL7302392A/xx
Priority to DE19732308831 priority patent/DE2308831A1/en
Priority to JP2074673A priority patent/JPS4892382A/ja
Publication of FR2172790A1 publication Critical patent/FR2172790A1/en
Application granted granted Critical
Publication of FR2172790B1 publication Critical patent/FR2172790B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
    • C07D279/18—[b, e]-condensed with two six-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compd. (I) (where R1 is 2,3,4- or 3,5,6-trimethoxyphenyl, PhCH2 or 3,4-methylenedioxyl phenyl and R2 is H or both R1 and R2 are Ph) are prepd. by reacting 2-chloro-10-beta-chloropropionyl phenothiazine (II) with NH2CHR1R2. Thus (I R1 = 3,4-methylenedioxyphenyl) R2 = H) is prepd. from (II) and piperonylamine.
FR7205875A 1972-02-22 1972-02-22 10-(beta amino propinyl) pheno thiazines - as diuretic, antiinflammat and anti-ulcer agents Granted FR2172790A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
BE795667D BE795667A (en) 1972-02-22 NEW DERIVATIVES OF 10 - (BETA-AMINO- PROPIONYL) PHENOTHIAZINE AND METHOD OF PREPARATION
FR7205875A FR2172790A1 (en) 1972-02-22 1972-02-22 10-(beta amino propinyl) pheno thiazines - as diuretic, antiinflammat and anti-ulcer agents
NL7302392A NL7302392A (en) 1972-02-22 1973-02-21
DE19732308831 DE2308831A1 (en) 1972-02-22 1973-02-22 NEW DERIVATIVES OF 10- (BETA-AMINO-PROPIONYL) -PHENOTHIAZINE AND METHOD OF MANUFACTURING
JP2074673A JPS4892382A (en) 1972-02-22 1973-02-22

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7205875A FR2172790A1 (en) 1972-02-22 1972-02-22 10-(beta amino propinyl) pheno thiazines - as diuretic, antiinflammat and anti-ulcer agents

Publications (2)

Publication Number Publication Date
FR2172790A1 true FR2172790A1 (en) 1973-10-05
FR2172790B1 FR2172790B1 (en) 1975-03-14

Family

ID=9093892

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7205875A Granted FR2172790A1 (en) 1972-02-22 1972-02-22 10-(beta amino propinyl) pheno thiazines - as diuretic, antiinflammat and anti-ulcer agents

Country Status (5)

Country Link
JP (1) JPS4892382A (en)
BE (1) BE795667A (en)
DE (1) DE2308831A1 (en)
FR (1) FR2172790A1 (en)
NL (1) NL7302392A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008070496A2 (en) 2006-12-01 2008-06-12 Bristol-Myers Squibb Company N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008070496A2 (en) 2006-12-01 2008-06-12 Bristol-Myers Squibb Company N- ( (3-benzyl) -2, 2- (bis-phenyl) -propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases

Also Published As

Publication number Publication date
JPS4892382A (en) 1973-11-30
DE2308831A1 (en) 1973-08-30
BE795667A (en) 1973-08-20
FR2172790B1 (en) 1975-03-14
NL7302392A (en) 1973-08-24

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Legal Events

Date Code Title Description
ST Notification of lapse