FR2255895A1 - Substd. benzo(b,d)pyrans - as anxiolytic, antidepressive and antipsychotic agents - Google Patents
Substd. benzo(b,d)pyrans - as anxiolytic, antidepressive and antipsychotic agentsInfo
- Publication number
- FR2255895A1 FR2255895A1 FR7443124A FR7443124A FR2255895A1 FR 2255895 A1 FR2255895 A1 FR 2255895A1 FR 7443124 A FR7443124 A FR 7443124A FR 7443124 A FR7443124 A FR 7443124A FR 2255895 A1 FR2255895 A1 FR 2255895A1
- Authority
- FR
- France
- Prior art keywords
- substd
- anxiolytic
- antidepressive
- pyrans
- benzo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000935 antidepressant agent Substances 0.000 title abstract 2
- 239000000164 antipsychotic agent Substances 0.000 title abstract 2
- 239000002249 anxiolytic agent Substances 0.000 title abstract 2
- 230000000949 anxiolytic effect Effects 0.000 title abstract 2
- 230000001430 anti-depressive effect Effects 0.000 title 1
- 125000005605 benzo group Chemical group 0.000 title 1
- 150000004880 oxines Chemical class 0.000 title 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 125000004434 sulfur atom Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000000561 anti-psychotic effect Effects 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Abstract
Benzopipans (some novel) of formula (I): (where - is a single a double bond; one of R1 and R3 amino opt. mono or di-alkyl substd. or a monoheterocyclic ring opt. contg. a further O, N or S atom and the other is H or amino opt. mono- or di-alkyl substd. or a monoheterocyclic ring opt. contg. a further O, N or S atom; each of R2 and R4 is H halogen, OH, alkoxy, alkyl or CF3; X is C=O or C(R5R6); R5 and R6 are H or alkyl;) are anxiolytic, antipsychotic and antidepressive agents.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT3208873 | 1973-12-27 | ||
| IT2029474 | 1974-02-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2255895A1 true FR2255895A1 (en) | 1975-07-25 |
Family
ID=26327481
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7443124A Withdrawn FR2255895A1 (en) | 1973-12-27 | 1974-12-27 | Substd. benzo(b,d)pyrans - as anxiolytic, antidepressive and antipsychotic agents |
Country Status (13)
| Country | Link |
|---|---|
| JP (1) | JPS5096574A (en) |
| AU (1) | AU7612874A (en) |
| BE (1) | BE823873A (en) |
| DD (1) | DD115661A5 (en) |
| DE (1) | DE2459076A1 (en) |
| DK (1) | DK680174A (en) |
| ES (1) | ES433299A1 (en) |
| FI (1) | FI367874A (en) |
| FR (1) | FR2255895A1 (en) |
| IL (1) | IL46614A0 (en) |
| NL (1) | NL7416454A (en) |
| NO (1) | NO744713L (en) |
| SE (1) | SE7416126L (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0003883A1 (en) * | 1978-02-17 | 1979-09-05 | Eli Lilly And Company | Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA817002B (en) * | 1980-10-20 | 1982-09-29 | Erba Farmitalia | 6-substituted 6h-dibenzo(b,d)pyran derivatives and process for their preparation |
| AU2003265663A1 (en) * | 2002-08-23 | 2004-03-11 | University Of Connecticut | Keto cannabinoids with therapeutic indications |
| JP2009528381A (en) * | 2006-02-28 | 2009-08-06 | パロマ ファーマシューティカルズ，インク． | Compositions and methods for treating diseases characterized by cell proliferation and angiogenesis |
| WO2012112791A1 (en) | 2011-02-16 | 2012-08-23 | Paloma Pharmaceuticals, Inc. | Radiation countermeasure agents |
-
1974
- 1974-12-05 AU AU76128/74A patent/AU7612874A/en not_active Expired
- 1974-12-13 DE DE19742459076 patent/DE2459076A1/en active Pending
- 1974-12-17 NL NL7416454A patent/NL7416454A/en unknown
- 1974-12-19 FI FI3678/74A patent/FI367874A/fi unknown
- 1974-12-20 SE SE7416126A patent/SE7416126L/xx unknown
- 1974-12-23 DK DK680174A patent/DK680174A/da unknown
- 1974-12-24 ES ES74433299A patent/ES433299A1/en not_active Expired
- 1974-12-24 DD DD183412A patent/DD115661A5/xx unknown
- 1974-12-27 BE BE151938A patent/BE823873A/en unknown
- 1974-12-27 NO NO744713A patent/NO744713L/no unknown
- 1974-12-27 JP JP50003007A patent/JPS5096574A/ja active Pending
- 1974-12-27 FR FR7443124A patent/FR2255895A1/en not_active Withdrawn
-
1975
- 1975-02-11 IL IL46614A patent/IL46614A0/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0003883A1 (en) * | 1978-02-17 | 1979-09-05 | Eli Lilly And Company | Amino-dibenzopyrans, their preparation, formulations containing them and their use as pharmaceuticals |
Also Published As
| Publication number | Publication date |
|---|---|
| BE823873A (en) | 1975-04-16 |
| SE7416126L (en) | 1975-06-30 |
| DE2459076A1 (en) | 1975-07-10 |
| DD115661A5 (en) | 1975-10-12 |
| DK680174A (en) | 1975-08-25 |
| FI367874A (en) | 1975-06-28 |
| IL46614A0 (en) | 1975-05-22 |
| NL7416454A (en) | 1975-07-01 |
| JPS5096574A (en) | 1975-07-31 |
| NO744713L (en) | 1975-07-21 |
| ES433299A1 (en) | 1976-12-01 |
| AU7612874A (en) | 1976-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |