FR2063918A1 - 5-aza indoles cns active - Google Patents
5-aza indoles cns activeInfo
- Publication number
- FR2063918A1 FR2063918A1 FR6931582A FR6931582A FR2063918A1 FR 2063918 A1 FR2063918 A1 FR 2063918A1 FR 6931582 A FR6931582 A FR 6931582A FR 6931582 A FR6931582 A FR 6931582A FR 2063918 A1 FR2063918 A1 FR 2063918A1
- Authority
- FR
- France
- Prior art keywords
- cns active
- halogen
- indoles
- aza indoles
- opt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- SRSKXJVMVSSSHB-UHFFFAOYSA-N 1h-pyrrolo[3,2-c]pyridine Chemical class N1=CC=C2NC=CC2=C1 SRSKXJVMVSSSHB-UHFFFAOYSA-N 0.000 title 1
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 208000001953 Hypotension Diseases 0.000 abstract 1
- -1 N-morpholino, benzylamino Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000003874 central nervous system depressant Substances 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000004985 dialkyl amino alkyl group Chemical group 0.000 abstract 1
- 125000000717 hydrazino group Chemical group [H]N([*])N([H])[H] 0.000 abstract 1
- 208000021822 hypotensive Diseases 0.000 abstract 1
- 230000001077 hypotensive effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
5-Azo indoles of formula (I) are CNS depressants, hypotensives, and immonodepressants (where R = opt branched alkyl, aralkyl (opt substd on aromatic ring), dialkylaminoalkyl, or cyclic; R1 = H or halogen R2 = OH, SH, halogen, or a nucleophic N-contg. group pref. N-pyrrolidino, N-piperidino, N-morpholino, benzylamino or hydrazino).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR6931582A FR2063918A1 (en) | 1969-09-17 | 1969-09-17 | 5-aza indoles cns active |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR6931582A FR2063918A1 (en) | 1969-09-17 | 1969-09-17 | 5-aza indoles cns active |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2063918A1 true FR2063918A1 (en) | 1971-07-16 |
FR2063918B1 FR2063918B1 (en) | 1973-08-10 |
Family
ID=9040170
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR6931582A Granted FR2063918A1 (en) | 1969-09-17 | 1969-09-17 | 5-aza indoles cns active |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2063918A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5764330A (en) * | 1994-06-27 | 1998-06-09 | Killer Loop S.P.A. | Device for interconnecting and pivoting two components of eyeglasses or protective elements for sports |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3377246A (en) * | 1966-09-20 | 1968-04-09 | Smith Kline French Lab | Antidepressant compositions and methods employing 7-n azaindoles |
-
1969
- 1969-09-17 FR FR6931582A patent/FR2063918A1/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3377246A (en) * | 1966-09-20 | 1968-04-09 | Smith Kline French Lab | Antidepressant compositions and methods employing 7-n azaindoles |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5764330A (en) * | 1994-06-27 | 1998-06-09 | Killer Loop S.P.A. | Device for interconnecting and pivoting two components of eyeglasses or protective elements for sports |
Also Published As
Publication number | Publication date |
---|---|
FR2063918B1 (en) | 1973-08-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |