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FI960095L - Menetelmä atsetidinonien syntetitoimiseksi - Google Patents

Menetelmä atsetidinonien syntetitoimiseksi Download PDF

Info

Publication number
FI960095L
FI960095L FI960095A FI960095A FI960095L FI 960095 L FI960095 L FI 960095L FI 960095 A FI960095 A FI 960095A FI 960095 A FI960095 A FI 960095A FI 960095 L FI960095 L FI 960095L
Authority
FI
Finland
Prior art keywords
azetidinones
synthesizing
synthesizing azetidinones
Prior art date
Application number
FI960095A
Other languages
English (en)
Swedish (sv)
Other versions
FI960095A0 (fi
Inventor
Tiruvettipuram K Thiruvengadam
Timothy Mcallister
Chou-Hong Tann
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22217215&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI960095(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of FI960095L publication Critical patent/FI960095L/fi
Publication of FI960095A0 publication Critical patent/FI960095A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Steroid Compounds (AREA)
FI960095A 1993-07-09 1996-01-09 Menetelmä atsetidinonien syntetitoimiseksi FI960095A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8935793A 1993-07-09 1993-07-09
PCT/US1994/007291 WO1995001961A1 (en) 1993-07-09 1994-07-01 Process for the synthesis of azetidinones

Publications (2)

Publication Number Publication Date
FI960095L true FI960095L (fi) 1996-01-09
FI960095A0 FI960095A0 (fi) 1996-01-09

Family

ID=22217215

Family Applications (1)

Application Number Title Priority Date Filing Date
FI960095A FI960095A0 (fi) 1993-07-09 1996-01-09 Menetelmä atsetidinonien syntetitoimiseksi

Country Status (21)

Country Link
US (1) US5728827A (fi)
EP (1) EP0707567B1 (fi)
JP (1) JP2840452B2 (fi)
KR (1) KR0176001B1 (fi)
CN (1) CN1071745C (fi)
AT (1) ATE205475T1 (fi)
AU (1) AU681419B2 (fi)
CA (1) CA2166784C (fi)
CZ (1) CZ7696A3 (fi)
DE (1) DE69428280T2 (fi)
DK (1) DK0707567T3 (fi)
ES (1) ES2160125T3 (fi)
FI (1) FI960095A0 (fi)
HU (1) HUT73237A (fi)
MX (1) MX9405152A (fi)
NO (1) NO306294B1 (fi)
NZ (1) NZ268798A (fi)
PL (1) PL312502A1 (fi)
PT (1) PT707567E (fi)
SK (1) SK3796A3 (fi)
WO (1) WO1995001961A1 (fi)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631365A (en) 1993-09-21 1997-05-20 Schering Corporation Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
US6207822B1 (en) 1998-12-07 2001-03-27 Schering Corporation Process for the synthesis of azetidinones
CA2353981C (en) * 1998-12-07 2005-04-26 Schering Corporation Process for the synthesis of azetidinones
AU4343500A (en) 1999-04-16 2000-11-02 Schering Corporation Use of azetidinone compounds
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
ATE331512T1 (de) 2001-01-26 2006-07-15 Schering Corp Verwendung azetidinone-substituierter verbindungen zur behandlung der sitosterolhämie
US20060287254A1 (en) * 2001-01-26 2006-12-21 Schering Corporation Use of substituted azetidinone compounds for the treatment of sitosterolemia
DK1413331T3 (da) 2001-01-26 2007-12-10 Schering Corp Kombinationer af peroxisomproliferatoraktiveret receptor (PPAR)-aktivatoren fenofibrat og sterolabsorptionsinhibitoren ezetimib til vaskulære indikationer
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
RS50386B (sr) * 2001-03-28 2009-12-31 Schering Corporation, Enantioselektivna sinteza intermedijarnih jedinjenja azetidinona
JP2005504091A (ja) 2001-09-21 2005-02-10 シェーリング　コーポレイション ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置
US7053080B2 (en) 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US20030204096A1 (en) * 2002-03-25 2003-10-30 Schering Corporation Enantioselective synthesis of azetidinone intermediate compounds
GB0215579D0 (en) 2002-07-05 2002-08-14 Astrazeneca Ab Chemical compounds
US7135556B2 (en) * 2002-07-19 2006-11-14 Schering Corporation NPC1L1 (NPC3) and methods of use thereof
US20040092499A1 (en) 2002-11-06 2004-05-13 Schering Corporation Methods and therapeutic combinations for the treatment of autoimmune disorders
ES2311806T3 (es) * 2003-03-07 2009-02-16 Schering Corporation Compuesto de azetidinona sustituidos, fornulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
WO2004081004A1 (en) 2003-03-07 2004-09-23 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
US7459442B2 (en) * 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
EP1601669B1 (en) * 2003-03-07 2008-12-24 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
AU2004308332B2 (en) * 2003-12-23 2008-04-10 Merck Sharp & Dohme Corp. Anti-hypercholesterolemic compounds
SA04250427A (ar) 2003-12-23 2005-12-03 استرازينيكا ايه بي مشتقات ثاني فينيل أزيتيدون
CA2553769C (en) * 2004-01-16 2011-01-04 Merck & Co., Inc. Npc1l1 (npc3) and methods of identifying ligands thereof
WO2005113496A1 (de) * 2004-05-21 2005-12-01 Sanofi-Aventis Deutschland Gmbh Verfahren zur herstellung von 1,4-diphenylazetidinon-derivaten
DE102004025071B4 (de) * 2004-05-21 2006-12-21 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Diphenylazetidinon-Derivaten
CN101119966B (zh) * 2004-12-20 2014-08-13 默沙东公司 合成2-吖丁啶酮的方法
ES2337727T3 (es) * 2005-06-20 2010-04-28 Schering Corporation Derivados de piperidina utiles como antagonistas de histamina h3.
SA06270191B1 (ar) 2005-06-22 2010-03-29 استرازينيكا ايه بي مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
EP1986489A2 (en) * 2006-02-24 2008-11-05 Schering Corporation Npc1l1 orthologues
AR060623A1 (es) 2006-04-27 2008-07-02 Astrazeneca Ab Compuestos derivados de 2-azetidinona y un metodo de preparacion
JP2010502702A (ja) * 2006-09-05 2010-01-28 シェーリング コーポレイション 脂質管理およびアテローム性動脈硬化症および脂肪肝の治療治療において使用される医薬組成物
WO2008032338A2 (en) * 2006-09-11 2008-03-20 Manne Satyanarayana Reddy Improved process for the preparation of ezetimibe and its intermediates
EA017349B1 (ru) 2007-01-24 2012-11-30 Крка Способ получения эзетимиба и его производных
WO2010113175A2 (en) 2009-04-01 2010-10-07 Matrix Laboratories Ltd Enzymatic process for the preparation of (s)-5-(4-fluoro-phenyl)-5-hydroxy- 1morpholin-4-yl-pentan-1-one, an intermediate of ezetimibe and further conversion to ezetimibe
CN104803858B (zh) * 2014-01-23 2019-03-01 东莞东阳光科研发有限公司 一种制备四丁基氟化铵三水合物的方法
ES2986788T3 (es) 2020-02-07 2024-11-12 Gasherbrum Bio Inc Agonistas heterocíclicos de GLP-1

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0333268A1 (en) * 1988-03-18 1989-09-20 Merck & Co. Inc. Process for synthesis of a chiral 3-beta hydrogen (3R) 4-aroyloxy azetidinone
US4876365A (en) * 1988-12-05 1989-10-24 Schering Corporation Intermediate compounds for preparing penems and carbapenems
US4983597A (en) * 1989-08-31 1991-01-08 Merck & Co., Inc. Beta-lactams as anticholesterolemic agents
US5085473A (en) * 1990-10-09 1992-02-04 Yuhe Yang Air actuated car curtain device
EP0596015B1 (en) * 1991-07-23 1997-10-01 Schering Corporation Substituted beta-lactam compounds useful as hypocholesterolemic agents and processes for the preparation thereof

Also Published As

Publication number Publication date
WO1995001961A1 (en) 1995-01-19
ES2160125T3 (es) 2001-11-01
CZ7696A3 (en) 1996-04-17
KR0176001B1 (ko) 1999-03-20
CA2166784C (en) 2001-12-11
NO306294B1 (no) 1999-10-18
SK3796A3 (en) 1997-02-05
AU681419B2 (en) 1997-08-28
HU9503748D0 (en) 1996-02-28
JPH08507085A (ja) 1996-07-30
NZ268798A (en) 1997-01-29
NO960083D0 (no) 1996-01-08
MX9405152A (es) 1995-01-31
DE69428280D1 (de) 2001-10-18
DE69428280T2 (de) 2002-06-13
CN1126989A (zh) 1996-07-17
PT707567E (pt) 2002-01-30
AU7214694A (en) 1995-02-06
EP0707567A1 (en) 1996-04-24
ATE205475T1 (de) 2001-09-15
DK0707567T3 (da) 2001-11-26
FI960095A0 (fi) 1996-01-09
PL312502A1 (en) 1996-04-29
US5728827A (en) 1998-03-17
KR960703853A (ko) 1996-08-31
JP2840452B2 (ja) 1998-12-24
HUT73237A (en) 1996-07-29
NO960083L (no) 1996-03-04
CN1071745C (zh) 2001-09-26
EP0707567B1 (en) 2001-09-12
CA2166784A1 (en) 1995-01-19

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