FI951596L - Menetelmä 10-desasetyylibakkatiini-III:n saamiseksi - Google Patents
Menetelmä 10-desasetyylibakkatiini-III:n saamiseksi Download PDFInfo
- Publication number
- FI951596L FI951596L FI951596A FI951596A FI951596L FI 951596 L FI951596 L FI 951596L FI 951596 A FI951596 A FI 951596A FI 951596 A FI951596 A FI 951596A FI 951596 L FI951596 L FI 951596L
- Authority
- FI
- Finland
- Prior art keywords
- deacetylbaccatin
- iii
- obtaining
- Prior art date
Links
- YWLXLRUDGLRYDR-ZHPRIASZSA-N 5beta,20-epoxy-1,7beta,10beta,13alpha-tetrahydroxy-9-oxotax-11-ene-2alpha,4alpha-diyl 4-acetate 2-benzoate Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](O)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 YWLXLRUDGLRYDR-ZHPRIASZSA-N 0.000 title 2
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Saccharide Compounds (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pyrane Compounds (AREA)
- Fats And Perfumes (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9211746 | 1992-10-05 | ||
FR9211746A FR2696463B1 (fr) | 1992-10-05 | 1992-10-05 | Procédé d'obtention de la désacétyl-10 baccatine III. |
PCT/FR1993/000972 WO1994007882A1 (fr) | 1992-10-05 | 1993-10-04 | Procede d'obtention de la desacetyl-10 baccatine iii |
FR9300972 | 1993-10-04 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI951596L true FI951596L (fi) | 1995-04-04 |
FI951596A0 FI951596A0 (fi) | 1995-04-04 |
FI109794B FI109794B (fi) | 2002-10-15 |
Family
ID=9434124
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI951596A FI109794B (fi) | 1992-10-05 | 1995-04-04 | Menetelmä 10-desasetyylibakkatiini-III:n saamiseksi |
Country Status (30)
Country | Link |
---|---|
US (1) | US5393895A (fi) |
EP (1) | EP0663910B1 (fi) |
JP (1) | JP3299754B2 (fi) |
KR (1) | KR100301236B1 (fi) |
CN (1) | CN1043530C (fi) |
AT (1) | ATE148883T1 (fi) |
AU (1) | AU680629B2 (fi) |
CA (1) | CA2146373C (fi) |
CZ (2) | CZ284615B6 (fi) |
DE (1) | DE69308155T2 (fi) |
DK (1) | DK0663910T3 (fi) |
EE (1) | EE03126B1 (fi) |
ES (1) | ES2098061T3 (fi) |
FI (1) | FI109794B (fi) |
FR (1) | FR2696463B1 (fi) |
GE (1) | GEP20001937B (fi) |
GR (1) | GR3022617T3 (fi) |
HU (1) | HU226862B1 (fi) |
LT (1) | LT3398B (fi) |
LV (1) | LV10621B (fi) |
MX (1) | MX9305771A (fi) |
NO (1) | NO310413B1 (fi) |
NZ (1) | NZ256450A (fi) |
PL (1) | PL177316B1 (fi) |
RU (1) | RU2107065C1 (fi) |
SK (1) | SK280949B6 (fi) |
TW (1) | TW255890B (fi) |
UA (1) | UA44227C2 (fi) |
WO (1) | WO1994007882A1 (fi) |
ZA (1) | ZA937313B (fi) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2696462B1 (fr) * | 1992-10-05 | 1994-11-25 | Rhone Poulenc Rorer Sa | Procédé d'obtention de la désacétyl-10 baccatine III. |
ES2290074T3 (es) | 1993-07-19 | 2008-02-16 | Angiotech Pharmaceuticals, Inc. | Composiciones anti-angiogenicas que contienen taxol y un vehiculo no biodegradable y su uso. |
ATE188880T1 (de) * | 1993-11-02 | 2000-02-15 | Rhone Poulenc Rorer Gmbh | Verfahren zum auftrennen eines gemisches |
FR2714053B1 (fr) * | 1993-12-22 | 1996-03-08 | Pf Medicament | Procédé d'extraction et d'isolement de la 10-désacétylbaccatine III. |
CN1112433A (zh) * | 1994-05-24 | 1995-11-29 | 郭明 | 红豆杉属植物提取物及其应用 |
CA2178541C (en) | 1995-06-07 | 2009-11-24 | Neal E. Fearnot | Implantable medical device |
FR2736355B1 (fr) * | 1995-07-07 | 1997-11-07 | Pf Medicament | Procede d'extraction et d'isolement de la 10-desacetylbaccatine iii |
US5750736A (en) * | 1996-07-11 | 1998-05-12 | Napro Biotherapeutics, Inc. | Method for acylating 10-deacetylbaccatin III selectively at the c-10 position |
US5965752A (en) * | 1996-08-23 | 1999-10-12 | Institut National De La Recherche Scientifique | Preparative scale isolation and purification of taxanes |
ES2195378T3 (es) | 1997-08-21 | 2003-12-01 | Univ Florida State | Procedimiento para la sintesis de taxanos. |
US6002024A (en) * | 1998-07-27 | 1999-12-14 | Dabur Research Foundation | Process for the isolation of 14β-hydroxy-10-deacetyl baccatin-III |
US6136989A (en) * | 1998-12-30 | 2000-10-24 | Phytogen Life Sciences, Incorporated | Method for high yield and large scale extraction of paclitaxel from paclitaxel-containing material |
US6281368B1 (en) | 2000-03-16 | 2001-08-28 | Napro Biotherapeutics, Inc. | Simple and efficient hydrazinolysis of C-10 and C-13 ester functionalities of taxanes to obtain 10-DAB III |
US6495705B2 (en) | 2000-03-16 | 2002-12-17 | Napro Biotherapeutics, Inc. | Efficient process for the production of 10-DAB III by selective hydrazinolysis of various taxanes |
CA2307393A1 (en) | 2000-05-01 | 2001-11-01 | The University Of British Columbia | Ginsenoside chemotherapy |
US20030157170A1 (en) * | 2001-03-13 | 2003-08-21 | Richard Liggins | Micellar drug delivery vehicles and precursors thereto and uses thereof |
CA2440935A1 (en) | 2001-03-13 | 2002-09-19 | Richard Liggins | Micellar drug delivery vehicles and precursors thereto and uses thereof |
EP1392254B1 (en) * | 2001-04-20 | 2007-06-06 | The University of British Columbia | Micellar drug delivery systems for hydrophobic drugs |
US7351542B2 (en) | 2002-05-20 | 2008-04-01 | The Regents Of The University Of California | Methods of modulating tubulin deacetylase activity |
EP1594459B1 (en) | 2002-12-30 | 2010-02-17 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
CA2525647A1 (en) | 2003-05-16 | 2005-02-24 | Intermune, Inc. | Synthetic chemokine receptor ligands and methods of use thereof |
US7407973B2 (en) | 2003-10-24 | 2008-08-05 | Intermune, Inc. | Use of pirfenidone in therapeutic regimens |
US7846940B2 (en) | 2004-03-31 | 2010-12-07 | Cordis Corporation | Solution formulations of sirolimus and its analogs for CAD treatment |
US7989490B2 (en) | 2004-06-02 | 2011-08-02 | Cordis Corporation | Injectable formulations of taxanes for cad treatment |
US8003122B2 (en) | 2004-03-31 | 2011-08-23 | Cordis Corporation | Device for local and/or regional delivery employing liquid formulations of therapeutic agents |
KR20070045219A (ko) * | 2004-07-02 | 2007-05-02 | 아이박스 파마슈티컬스 에스.알.오. | 파클리탁셀과 세팔로마닌의 분리 방법 |
US7597884B2 (en) | 2004-08-09 | 2009-10-06 | Alios Biopharma, Inc. | Hyperglycosylated polypeptide variants and methods of use |
WO2006089218A2 (en) | 2005-02-17 | 2006-08-24 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for modulating angiogenesis |
WO2007062036A2 (en) | 2005-11-21 | 2007-05-31 | Med Institute, Inc. | Implantable medical device coatings with biodegradable elastomer and releasable therapeutic agent |
WO2007107305A2 (en) | 2006-03-22 | 2007-09-27 | Medigene Ag | Treatment of triple receptor negative breast cancer |
WO2008005284A2 (en) | 2006-06-30 | 2008-01-10 | Cook Incorporated | Methods of manufacturing and modifying taxane coatings for implantable medical devices |
US8409601B2 (en) | 2008-03-31 | 2013-04-02 | Cordis Corporation | Rapamycin coated expandable devices |
US8420110B2 (en) | 2008-03-31 | 2013-04-16 | Cordis Corporation | Drug coated expandable devices |
US8273404B2 (en) | 2008-05-19 | 2012-09-25 | Cordis Corporation | Extraction of solvents from drug containing polymer reservoirs |
EP2859916B1 (en) | 2008-05-22 | 2017-11-29 | Galera Labs, LLC | Combination of an antimitotic agent and a selective superoxide dismutase mimetic in antitumor therapy |
WO2010005850A1 (en) | 2008-07-08 | 2010-01-14 | The J. David Gladstone Institutes | Methods and compositions for modulating angiogenesis |
US8642063B2 (en) | 2008-08-22 | 2014-02-04 | Cook Medical Technologies Llc | Implantable medical device coatings with biodegradable elastomer and releasable taxane agent |
US20120303115A1 (en) | 2011-05-25 | 2012-11-29 | Dadino Ronald C | Expandable devices coated with a rapamycin composition |
US20120302954A1 (en) | 2011-05-25 | 2012-11-29 | Zhao Jonathon Z | Expandable devices coated with a paclitaxel composition |
EP2760848B1 (en) | 2011-09-26 | 2018-11-28 | Fresenius Kabi Oncology Limited | Processes for the preparation of cabazitaxel involving c(7)-oh and c(13)-oh silylation or just c(7)-oh silylation |
US9956385B2 (en) | 2012-06-28 | 2018-05-01 | The Spectranetics Corporation | Post-processing of a medical device to control morphology and mechanical properties |
EP3539563A1 (en) | 2012-07-19 | 2019-09-18 | Redwood Bioscience, Inc. | Antibody specific for cd22 and methods of use thereof |
AU2013341711A1 (en) | 2012-11-12 | 2015-05-21 | Redwood Bioscience, Inc. | Compounds and methods for producing a conjugate |
CN103804326A (zh) * | 2012-11-15 | 2014-05-21 | 刘胜远 | 一种从含10-去乙酰基巴卡亭ⅲ的浸膏分离和提纯10-去乙酰基巴卡亭ⅲ的方法 |
LT2956175T (lt) | 2013-02-15 | 2017-12-11 | The Regents Of The University Of California | Chimerinis antigeno receptorius ir jo panaudojimo būdai |
CN103145652B (zh) * | 2013-03-05 | 2015-09-30 | 无锡尔云科技有限公司 | 一种从红豆杉属植物中提取紫杉醇及其衍生物的方法 |
CN105358531B (zh) | 2013-03-14 | 2017-11-14 | 利兰-斯坦福大学初级学院的董事会 | 线粒体醛脱氢酶‑2调节剂和其使用方法 |
JP6745218B2 (ja) | 2013-11-27 | 2020-08-26 | レッドウッド バイオサイエンス, インコーポレイテッド | ヒドラジニル−ピロロ化合物及び複合体を生成するための方法 |
WO2015127137A1 (en) | 2014-02-19 | 2015-08-27 | Aldea Pharmaceuticals, Inc. | Mitochondrial aldehyde dehydrogenase 2 (aldh2) binding polycyclic amides and their use for the treatment of cancer |
US10517961B2 (en) | 2015-09-25 | 2019-12-31 | ZY Therapeutics, Inc. | Drug formulation based on particulates comprising polysaccharide-vitamin conjugate |
US10654875B2 (en) | 2015-11-12 | 2020-05-19 | The Board Of Trustees Of The Leland Stanford Junior University | Cell-penetrating, guanidinium-rich oligophosphotriesters for drug and probe delivery |
TWI760319B (zh) | 2015-12-30 | 2022-04-11 | 杏國新藥股份有限公司 | 乳癌治療 |
JP2019515677A (ja) | 2016-04-26 | 2019-06-13 | アール.ピー.シェーラー テクノロジーズ エルエルシー | 抗体複合体ならびにそれを作製および使用する方法 |
UA123020C2 (uk) | 2016-06-01 | 2021-02-03 | Сервьє Айпі Юкей Лімітед | Склади поліалкіленоксид-аспарагінази та способи їхнього виготовлення й використання |
TWI852903B (zh) | 2017-01-05 | 2024-08-21 | 杏國新藥股份有限公司 | 胰臟癌治療 |
SG11201906468TA (en) | 2017-01-18 | 2019-08-27 | F1 Oncology Inc | Chimeric antigen receptors against axl or ror2 and methods of use thereof |
EP3388082A1 (en) | 2017-04-13 | 2018-10-17 | Galera Labs, LLC | Combination cancer immunotherapy with pentaaza macrocyclic ring complex |
WO2018218004A1 (en) | 2017-05-24 | 2018-11-29 | The Board Of Regents Of The University Of Texas System | Linkers for antibody drug conjugates |
EA202091832A1 (ru) | 2018-01-31 | 2021-01-11 | ГАЛЕРА ЛЭБЗ, ЭлЭлСи | Комбинированная терапия злокачественных новообразований макроциклическим кольцевым комплексом пентаазы и противоопухолевым агентом на основе платины |
BR112020020930A2 (pt) | 2018-04-11 | 2021-03-02 | Ohio State Innovation Foundation | composição de liberação de fármaco, método para tratar um distúrbio oftalmológico e kit |
CN108904137A (zh) * | 2018-05-27 | 2018-11-30 | 肖军威 | 一种卫生巾芯片的制备方法及卫生巾芯片的加工设备 |
US11897928B2 (en) | 2018-07-18 | 2024-02-13 | Manzanita Pharmaceuticals, Inc. | Conjugates for delivering an anti-cancer agent to nerve cells, methods of use and methods of making thereof |
US11529402B2 (en) | 2019-01-14 | 2022-12-20 | Ignite Immunotherapy, Inc. | Recombinant vaccinia virus and methods of use thereof |
US11685904B2 (en) | 2019-02-14 | 2023-06-27 | Ignite Immunotherapy, Inc. | Recombinant vaccinia virus and methods of use thereof |
BR112021019701A2 (pt) | 2019-04-02 | 2021-12-14 | Kenjockety Biotechnology Inc | Anticorpos multiespecíficos para antígeno de câncer de bomba de efluxo e composições, reagentes, kits e métodos relacionados aos mesmos |
CN110317183B (zh) * | 2019-08-08 | 2021-03-12 | 无锡紫杉药业有限公司 | 一种红豆杉天然提取产物的纯化方法 |
CA3163805A1 (en) | 2019-12-12 | 2021-06-17 | Ignite Immunotherapy, Inc. | Variant oncolytic vaccinia virus and methods of use thereof |
CA3164608A1 (en) | 2020-01-29 | 2021-08-05 | Kenjockety Biotechnology, Inc. | Anti-mdr1 antibodies and uses thereof |
US20230212305A1 (en) | 2020-06-04 | 2023-07-06 | Kenjockety Biotechnology, Inc. | Anti-abcg2 antibodies and uses thereof |
WO2021247423A1 (en) | 2020-06-04 | 2021-12-09 | Kenjockety Biotechnology, Inc. | Abcg2 efflux pump-cancer antigen multi-specific antibodies and compositions, reagents, kits and methods related thereto |
CA3189291A1 (en) | 2020-07-14 | 2022-01-20 | Pfizer Inc. | Recombinant vaccinia virus |
CN116490522A (zh) | 2020-09-02 | 2023-07-25 | 肯乔克蒂生物技术股份有限公司 | 抗abcc1抗体及其应用 |
US20240010747A1 (en) | 2020-11-13 | 2024-01-11 | Kenjockety Biotechnology, Inc. | Anti-mrp4 (encoded by abcc4 gene) antibodies and uses thereof |
JP2023551203A (ja) | 2020-11-20 | 2023-12-07 | アール.ピー.シェーラー テクノロジーズ、エルエルシー | 抗体-薬物コンジュゲートのためのグリコシド二重切断リンカー |
CN112694458A (zh) * | 2020-12-29 | 2021-04-23 | 重庆臻源红豆杉发展有限公司 | 一种10-去乙酰基巴卡亭ⅲ提取纯化方法 |
AU2022413942A1 (en) | 2021-12-13 | 2024-05-30 | William Robert Arathoon Living Trust Dated August 29, 2016 | Anti-abcb1 antibodies |
WO2023159220A1 (en) | 2022-02-18 | 2023-08-24 | Kenjockety Biotechnology, Inc. | Anti-cd47 antibodies |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
FR2629818B1 (fr) | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
FR2629819B1 (fr) | 1988-04-06 | 1990-11-16 | Rhone Poulenc Sante | Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii |
US5175315A (en) | 1989-05-31 | 1992-12-29 | Florida State University | Method for preparation of taxol using β-lactam |
US5136060A (en) | 1989-11-14 | 1992-08-04 | Florida State University | Method for preparation of taxol using an oxazinone |
US5380916A (en) | 1990-11-02 | 1995-01-10 | University Of Florida | Method for the isolation and purification of taxane derivatives |
MX9102128A (es) | 1990-11-23 | 1992-07-08 | Rhone Poulenc Rorer Sa | Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene |
WO1992018492A1 (en) * | 1991-04-19 | 1992-10-29 | The University Of Mississippi | Methods and compositions for isolating taxanes |
IT1258838B (it) * | 1992-01-31 | 1996-02-29 | Indena Spa | Processo per l'estrazione di tassolo e derivati da cultivar del genere taxus |
-
1992
- 1992-10-05 FR FR9211746A patent/FR2696463B1/fr not_active Expired - Lifetime
-
1993
- 1993-01-27 US US08/010,083 patent/US5393895A/en not_active Expired - Lifetime
- 1993-04-10 UA UA95038244A patent/UA44227C2/uk unknown
- 1993-04-21 CN CN93104616A patent/CN1043530C/zh not_active Expired - Lifetime
- 1993-09-21 MX MX9305771A patent/MX9305771A/es unknown
- 1993-10-01 ZA ZA937313A patent/ZA937313B/xx unknown
- 1993-10-02 TW TW082108103A patent/TW255890B/zh not_active IP Right Cessation
- 1993-10-04 WO PCT/FR1993/000972 patent/WO1994007882A1/fr active IP Right Grant
- 1993-10-04 EP EP93921987A patent/EP0663910B1/fr not_active Expired - Lifetime
- 1993-10-04 PL PL93308244A patent/PL177316B1/pl unknown
- 1993-10-04 DK DK93921987.9T patent/DK0663910T3/da active
- 1993-10-04 DE DE69308155T patent/DE69308155T2/de not_active Expired - Lifetime
- 1993-10-04 RU RU95110687/04A patent/RU2107065C1/ru active
- 1993-10-04 ES ES93921987T patent/ES2098061T3/es not_active Expired - Lifetime
- 1993-10-04 CZ CZ95845A patent/CZ284615B6/cs not_active IP Right Cessation
- 1993-10-04 LV LVP-93-1120A patent/LV10621B/xx unknown
- 1993-10-04 LT LTIP1397A patent/LT3398B/lt not_active IP Right Cessation
- 1993-10-04 NZ NZ256450A patent/NZ256450A/en not_active IP Right Cessation
- 1993-10-04 AT AT93921987T patent/ATE148883T1/de active
- 1993-10-04 GE GEAP19932511A patent/GEP20001937B/en unknown
- 1993-10-04 CA CA002146373A patent/CA2146373C/fr not_active Expired - Lifetime
- 1993-10-04 AU AU51155/93A patent/AU680629B2/en not_active Expired
- 1993-10-04 JP JP50879294A patent/JP3299754B2/ja not_active Expired - Lifetime
- 1993-10-04 KR KR1019950701306A patent/KR100301236B1/ko not_active Expired - Lifetime
- 1993-10-04 HU HU9500973A patent/HU226862B1/hu unknown
- 1993-10-04 SK SK433-95A patent/SK280949B6/sk not_active IP Right Cessation
-
1994
- 1994-11-18 EE EE9400364A patent/EE03126B1/xx unknown
-
1995
- 1995-04-03 NO NO19951282A patent/NO310413B1/no not_active IP Right Cessation
- 1995-04-04 FI FI951596A patent/FI109794B/fi not_active IP Right Cessation
-
1997
- 1997-02-20 GR GR960402767T patent/GR3022617T3/el unknown
-
1998
- 1998-02-06 CZ CZ1998367A patent/CZ287065B6/cs not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC | Transfer of assignment of patent |
Owner name: AVENTIS PHARMA S.A. |
|
MA | Patent expired |