NO306294B1 - FremgangsmÕte for fremstilling av azetidinoner - Google Patents

FremgangsmÕte for fremstilling av azetidinoner

Info

Publication number: NO306294B1
Authority: NO; Norway
Prior art keywords: substituted; pct; beta; amino; azetidinones
Prior art date: 1993-07-09

Application number

NO960083A

Other languages

English (en)

Other versions

NO960083D0 (no

NO960083L (no

Inventor

Tiruvettipuram K Thiruvengadam

Timothy Mcallister

Chou-Hong Tann

Original Assignee

Schering Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-07-09

Filing date

1996-01-08

Publication date

1999-10-18

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22217215&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO306294(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-01-08 Application filed by Schering Corp filed Critical Schering Corp

1996-01-08 Publication of NO960083D0 publication Critical patent/NO960083D0/no

1996-03-04 Publication of NO960083L publication Critical patent/NO960083L/no

1999-10-18 Publication of NO306294B1 publication Critical patent/NO306294B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

NO960083A 1993-07-09 1996-01-08 FremgangsmÕte for fremstilling av azetidinoner NO306294B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US8935793A	1993-07-09	1993-07-09
PCT/US1994/007291 WO1995001961A1 (en)	1993-07-09	1994-07-01	Process for the synthesis of azetidinones

Publications (3)

Publication Number	Publication Date
NO960083D0 NO960083D0 (no)	1996-01-08
NO960083L NO960083L (no)	1996-03-04
NO306294B1 true NO306294B1 (no)	1999-10-18

Family

ID=22217215

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO960083A NO306294B1 (no)	1993-07-09	1996-01-08	FremgangsmÕte for fremstilling av azetidinoner

Country Status (21)

Country	Link
US (1)	US5728827A (no)
EP (1)	EP0707567B1 (no)
JP (1)	JP2840452B2 (no)
KR (1)	KR0176001B1 (no)
CN (1)	CN1071745C (no)
AT (1)	ATE205475T1 (no)
AU (1)	AU681419B2 (no)
CA (1)	CA2166784C (no)
CZ (1)	CZ7696A3 (no)
DE (1)	DE69428280T2 (no)
DK (1)	DK0707567T3 (no)
ES (1)	ES2160125T3 (no)
FI (1)	FI960095L (no)
HU (1)	HUT73237A (no)
MX (1)	MX9405152A (no)
NO (1)	NO306294B1 (no)
NZ (1)	NZ268798A (no)
PL (1)	PL312502A1 (no)
PT (1)	PT707567E (no)
SK (1)	SK3796A3 (no)
WO (1)	WO1995001961A1 (no)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5631365A (en)	1993-09-21	1997-05-20	Schering Corporation	Hydroxy-substituted azetidinone compounds useful as hypocholesterolemic agents
AU2030100A (en) *	1998-12-07	2000-06-26	Schering Corporation	Process for the synthesis of azetidinones
US6207822B1 (en)	1998-12-07	2001-03-27	Schering Corporation	Process for the synthesis of azetidinones
AR023463A1 (es) *	1999-04-16	2002-09-04	Schering Corp	Uso de compuestos de azetidinona
US6982251B2 (en)	2000-12-20	2006-01-03	Schering Corporation	Substituted 2-azetidinones useful as hypocholesterolemic agents
US20060287254A1 (en) *	2001-01-26	2006-12-21	Schering Corporation	Use of substituted azetidinone compounds for the treatment of sitosterolemia
US7071181B2 (en)	2001-01-26	2006-07-04	Schering Corporation	Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
US7417039B2 (en)	2001-01-26	2008-08-26	Schering Corporation	Use of substituted azetidinone compounds for the treatment of sitosterolemia
CN100509058C (zh)	2001-01-26	2009-07-08	先灵公司	过氧化物酶体增殖物激活受体(ppar)活化剂和甾醇吸收抑制剂的组合药以及对于血管适应症的治疗
SI1373230T1 (sl) *	2001-03-28	2005-12-31	Schering Corp	Enantioselektivna sinteza azetidinonskih intermediatnih spojin
US7132415B2 (en) *	2001-09-21	2006-11-07	Schering Corporation	Methods and therapeutic combinations for the treatment of xanthoma using sterol absorption inhibitors
US7053080B2 (en)	2001-09-21	2006-05-30	Schering Corporation	Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
US20030204096A1 (en) *	2002-03-25	2003-10-30	Schering Corporation	Enantioselective synthesis of azetidinone intermediate compounds
GB0215579D0 (en)	2002-07-05	2002-08-14	Astrazeneca Ab	Chemical compounds
US7135556B2 (en) *	2002-07-19	2006-11-14	Schering Corporation	NPC1L1 (NPC3) and methods of use thereof
CA2504878A1 (en)	2002-11-06	2004-05-27	Schering Corporation	Cholesterol absorption inhibitors for the treatment of demyelination
MXPA05009501A (es) *	2003-03-07	2005-10-18	Schering Corp	Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
JP2006519869A (ja)	2003-03-07	2006-08-31	シェーリング　コーポレイション	置換アゼチジノン化合物、置換アゼチジノン化合物を調製するためのプロセス、それらの処方物および使用
US7459442B2 (en) *	2003-03-07	2008-12-02	Schering Corporation	Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
JP5137228B2 (ja)	2003-03-07	2013-02-06	メルク・シャープ・アンド・ドーム・コーポレーション	高コレステロール血症の処置のための置換アゼチジノン化合物、置換アゼチジノン処方物およびそれらの使用
WO2005062824A2 (en) *	2003-12-23	2005-07-14	Merck & Co., Inc.	Anti-hypercholesterolemic compounds
US7871998B2 (en)	2003-12-23	2011-01-18	Astrazeneca Ab	Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity
EP1723414A4 (en) *	2004-01-16	2008-03-26	Merck & Co Inc	NPC1L1 (NPC3) AND METHOD FOR IDENTIFYING ITS LIGANDS
JP2007538042A (ja) *	2004-05-21	2007-12-27	サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング	１，４−ジフェニルアゼチジノン誘導体の製造方法
DE102004025071B4 (de) *	2004-05-21	2006-12-21	Sanofi-Aventis Deutschland Gmbh	Verfahren zur Herstellung von Diphenylazetidinon-Derivaten
SG158132A1 (en)	2004-12-20	2010-01-29	Schering Corp	Process for the synthesis of azetidinones
JP2008546784A (ja) *	2005-06-20	2008-12-25	シェーリングコーポレイション	ヒスタミンｈ３アンタゴニストとして有用なピペリジン誘導体
SA06270191B1 (ar)	2005-06-22	2010-03-29	استرازينيكا ايه بي	مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
EP1986489A2 (en) *	2006-02-24	2008-11-05	Schering Corporation	Npc1l1 orthologues
AR060623A1 (es)	2006-04-27	2008-07-02	Astrazeneca Ab	Compuestos derivados de 2-azetidinona y un metodo de preparacion
EP2059241A1 (en) *	2006-09-05	2009-05-20	Schering Corporation	Pharmaceutical combinations for lipid management and in the treatment of atherosclerosis and hepatic steatosis
WO2008032338A2 (en) *	2006-09-11	2008-03-20	Manne Satyanarayana Reddy	Improved process for the preparation of ezetimibe and its intermediates
EA017349B1 (ru)	2007-01-24	2012-11-30	Крка	Способ получения эзетимиба и его производных
EP2414529A2 (en)	2009-04-01	2012-02-08	Matrix Laboratories Ltd	Enzymatic process for the preparation of (s)-5-(4-fluoro-phenyl)-5-hydroxy- 1morpholin-4-yl-pentan-1-one, an intermediate of ezetimibe and further conversion to ezetimibe
CN104803858B (zh) *	2014-01-23	2019-03-01	东莞东阳光科研发有限公司	一种制备四丁基氟化铵三水合物的方法
ES2986788T3 (es)	2020-02-07	2024-11-12	Gasherbrum Bio Inc	Agonistas heterocíclicos de GLP-1

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0333268A1 (en) *	1988-03-18	1989-09-20	Merck & Co. Inc.	Process for synthesis of a chiral 3-beta hydrogen (3R) 4-aroyloxy azetidinone
US4876365A (en) *	1988-12-05	1989-10-24	Schering Corporation	Intermediate compounds for preparing penems and carbapenems
US4983597A (en) *	1989-08-31	1991-01-08	Merck & Co., Inc.	Beta-lactams as anticholesterolemic agents
US5085473A (en) *	1990-10-09	1992-02-04	Yuhe Yang	Air actuated car curtain device
MY131273A (en) *	1991-07-23	2007-07-31	Schering Corp	Substituted beta-lactam compounds useful as hypocholesterolemic agents and processes for the preparation thereof

1994
- 1994-07-01 ES ES94921407T patent/ES2160125T3/es not_active Expired - Lifetime
- 1994-07-01 SK SK37-96A patent/SK3796A3/sk unknown
- 1994-07-01 AU AU72146/94A patent/AU681419B2/en not_active Ceased
- 1994-07-01 PL PL94312502A patent/PL312502A1/xx unknown
- 1994-07-01 NZ NZ268798A patent/NZ268798A/en unknown
- 1994-07-01 PT PT94921407T patent/PT707567E/pt unknown
- 1994-07-01 AT AT94921407T patent/ATE205475T1/de active
- 1994-07-01 DE DE69428280T patent/DE69428280T2/de not_active Expired - Lifetime
- 1994-07-01 JP JP7504054A patent/JP2840452B2/ja not_active Expired - Fee Related
- 1994-07-01 US US08/578,594 patent/US5728827A/en not_active Expired - Lifetime
- 1994-07-01 CZ CZ9676A patent/CZ7696A3/cs unknown
- 1994-07-01 KR KR1019960700068A patent/KR0176001B1/ko not_active Expired - Fee Related
- 1994-07-01 CA CA002166784A patent/CA2166784C/en not_active Expired - Fee Related
- 1994-07-01 DK DK94921407T patent/DK0707567T3/da active
- 1994-07-01 HU HU9503748A patent/HUT73237A/hu unknown
- 1994-07-01 EP EP94921407A patent/EP0707567B1/en not_active Expired - Lifetime
- 1994-07-01 WO PCT/US1994/007291 patent/WO1995001961A1/en active IP Right Grant
- 1994-07-01 CN CN94192732A patent/CN1071745C/zh not_active Expired - Fee Related
- 1994-07-06 MX MX9405152A patent/MX9405152A/es not_active IP Right Cessation
1996
- 1996-01-08 NO NO960083A patent/NO306294B1/no not_active IP Right Cessation
- 1996-01-09 FI FI960095A patent/FI960095L/fi unknown

Also Published As

Publication number	Publication date
ES2160125T3 (es)	2001-11-01
DE69428280D1 (de)	2001-10-18
AU7214694A (en)	1995-02-06
FI960095A0 (fi)	1996-01-09
WO1995001961A1 (en)	1995-01-19
JPH08507085A (ja)	1996-07-30
CZ7696A3 (en)	1996-04-17
ATE205475T1 (de)	2001-09-15
MX9405152A (es)	1995-01-31
AU681419B2 (en)	1997-08-28
FI960095L (fi)	1996-01-09
DK0707567T3 (da)	2001-11-26
DE69428280T2 (de)	2002-06-13
JP2840452B2 (ja)	1998-12-24
PL312502A1 (en)	1996-04-29
CA2166784A1 (en)	1995-01-19
NZ268798A (en)	1997-01-29
SK3796A3 (en)	1997-02-05
EP0707567B1 (en)	2001-09-12
HU9503748D0 (en)	1996-02-28
NO960083D0 (no)	1996-01-08
KR0176001B1 (ko)	1999-03-20
KR960703853A (ko)	1996-08-31
NO960083L (no)	1996-03-04
CN1071745C (zh)	2001-09-26
PT707567E (pt)	2002-01-30
US5728827A (en)	1998-03-17
HUT73237A (en)	1996-07-29
CN1126989A (zh)	1996-07-17
EP0707567A1 (en)	1996-04-24
CA2166784C (en)	2001-12-11

Publication	Publication Date	Title
NO306294B1 (no)	1999-10-18	FremgangsmÕte for fremstilling av azetidinoner
BG108168A (en)	2004-09-30	Enantioselective synthesis of azetidinone intermediate compounds
PL318100A1 (en)	1997-05-12	2-[(dihydro) pyrazolyl-3'-oxymethylene]anilides, method of obtaining them and their application
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DE69433984D1 (de)	2004-10-14	Arylpiperazinderivate von indol als liganden der rezeptoren 5 ht1-like, 5 ht1b und 5 ht1d
MX9708621A (es)	1998-02-28	AGONISTAS beta-ADRENERGICOS, COMPOSICIONES QUE LOS CONTIENEN Y USO DE LOS MISMOS.
YU78303A (sh)	2006-05-25	Postupak za dobijanje 1,3-supstituisanih indena i azapolicikličnih jedinjenja sa pripojenim arilom
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Legal Events

Date	Code	Title	Description
2001-03-05	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN JANUARY 2001