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ES2105442T3 - Analogos de eritropoyetina con sitios adicionales de glicosilacion. - Google Patents

Analogos de eritropoyetina con sitios adicionales de glicosilacion.

Info

Publication number
ES2105442T3
ES2105442T3 ES94112732T ES94112732T ES2105442T3 ES 2105442 T3 ES2105442 T3 ES 2105442T3 ES 94112732 T ES94112732 T ES 94112732T ES 94112732 T ES94112732 T ES 94112732T ES 2105442 T3 ES2105442 T3 ES 2105442T3
Authority
ES
Spain
Prior art keywords
analogs
erythropoyetin
additional
glycosilation
glycosilation sites
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94112732T
Other languages
English (en)
Other versions
ES2105442T5 (es
Inventor
Steven G Elliot
Thomas E Byrne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen K A Inc
Original Assignee
Kirin Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22319789&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2105442(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kirin Amgen Inc filed Critical Kirin Amgen Inc
Publication of ES2105442T3 publication Critical patent/ES2105442T3/es
Application granted granted Critical
Publication of ES2105442T5 publication Critical patent/ES2105442T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/505—Erythropoietin [EPO]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE PRESENTAN ANALOGOS DE LA ERITROPOYETINA QUE TIENEN AL MENOS UNA REGION ADICIONAL PARA LA GLICOSILACION Y UNA REDISPOSICION DE LA MENOS UNA REGION PARA LA GLICOSILACION. LA INVENCION TAMBIEN SE REFIERE A SECUENCIAS DE ADN QUE CODIFICAN DICHOS ANALOGOS DE ERITROPOYETINA Y A PLASMIDOS RECOMBINANTES Y CELULAS HUESPEDES PARA LA EXPRESION DE LOS ANALOGOS.
ES94112732T 1993-08-17 1994-08-16 Analogos de eritropoyetina con sitios adicionales de glicosilacion. Expired - Lifetime ES2105442T5 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10801693A 1993-08-17 1993-08-17
US108016 1993-08-17

Publications (2)

Publication Number Publication Date
ES2105442T3 true ES2105442T3 (es) 1997-10-16
ES2105442T5 ES2105442T5 (es) 2005-07-16

Family

ID=22319789

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94112732T Expired - Lifetime ES2105442T5 (es) 1993-08-17 1994-08-16 Analogos de eritropoyetina con sitios adicionales de glicosilacion.

Country Status (27)

Country Link
EP (1) EP0640619B2 (es)
JP (3) JP2938572B2 (es)
KR (2) KR100328769B1 (es)
CN (1) CN1057534C (es)
AT (1) ATE155796T1 (es)
AU (1) AU677097B2 (es)
CA (1) CA2147124C (es)
CZ (3) CZ291229B6 (es)
DE (2) DE69404401T3 (es)
DK (1) DK0640619T4 (es)
ES (1) ES2105442T5 (es)
FI (1) FI117136B (es)
GR (1) GR3024815T3 (es)
HK (1) HK1001589A1 (es)
HU (1) HU220334B (es)
IL (4) IL110669A (es)
LU (1) LU90850I2 (es)
LV (1) LV10972B (es)
NL (1) NL300075I2 (es)
NO (2) NO323104B1 (es)
NZ (1) NZ273134A (es)
RU (1) RU2159814C2 (es)
SI (1) SI0640619T2 (es)
SK (1) SK282003B6 (es)
UA (1) UA49793C2 (es)
WO (1) WO1995005465A1 (es)
ZA (1) ZA946122B (es)

Families Citing this family (242)

* Cited by examiner, † Cited by third party
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