AR065613A1 - Agentes de proteccion para organos transplantados - Google Patents
Agentes de proteccion para organos transplantadosInfo
- Publication number
- AR065613A1 AR065613A1 ARP080100920A ARP080100920A AR065613A1 AR 065613 A1 AR065613 A1 AR 065613A1 AR P080100920 A ARP080100920 A AR P080100920A AR P080100920 A ARP080100920 A AR P080100920A AR 065613 A1 AR065613 A1 AR 065613A1
- Authority
- AR
- Argentina
- Prior art keywords
- transplanted organs
- erythropoietin
- organs
- protection agents
- active ingredient
- Prior art date
Links
- 210000000056 organ Anatomy 0.000 title abstract 7
- 239000011814 protection agent Substances 0.000 title 1
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 abstract 6
- 102000003951 Erythropoietin Human genes 0.000 abstract 5
- 108090000394 Erythropoietin Proteins 0.000 abstract 5
- 229940105423 erythropoietin Drugs 0.000 abstract 5
- 239000000203 mixture Substances 0.000 abstract 4
- 238000002054 transplantation Methods 0.000 abstract 3
- 206010063837 Reperfusion injury Diseases 0.000 abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000004083 survival effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Environmental Sciences (AREA)
- Surgery (AREA)
- Toxicology (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Composiciones que contienen eritropoyetina (EPO) como un ingrediente activo, destinadas a proteger organos transplantados, estimular la supervivencia de organos transplantados o preservar organos para transplante. Reivindicacion 4: La composicionde acuerdo a cualquiera de las reivindicaciones 1 a 3, caracterizada porque la eritropoyetina es eritropoyetina desialilada. Reivindicacion 5: Un método de proteccion de organos transplantados contra el dano por reperfusion durante el transplante,caracterizado porque comprende el paso de administrar directamente una composicion que comprende eritropoyetina como un ingrediente activo a los organos transplantados. Reivindicacion 7: El uso de eritropoyetina, caracterizado por aplicarse a lafabricacion de una composicion medicinal destinada a proteger organos transplantados contra el dano por reperfusion durante el transplante.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2007059632 | 2007-03-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AR065613A1 true AR065613A1 (es) | 2009-06-17 |
Family
ID=39759442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ARP080100920A AR065613A1 (es) | 2007-03-09 | 2008-03-06 | Agentes de proteccion para organos transplantados |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20100137191A1 (es) |
| EP (1) | EP2143439A4 (es) |
| JP (1) | JP5763882B2 (es) |
| CN (1) | CN101631561A (es) |
| AR (1) | AR065613A1 (es) |
| CA (1) | CA2680236A1 (es) |
| CL (1) | CL2008000701A1 (es) |
| PE (1) | PE20081879A1 (es) |
| TW (1) | TW200904825A (es) |
| WO (1) | WO2008111503A1 (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HUE035168T2 (en) | 2008-09-26 | 2018-05-02 | Ambrx Inc | Modified animal erythropoietin polypeptides and their applications |
| NL2010225C2 (en) * | 2013-02-01 | 2014-08-04 | Conradus Ghosal Gho | Composition and method for preserving, transporting and storing living biological materials. |
| CN116492448A (zh) * | 2023-04-12 | 2023-07-28 | 深圳赛保尔生物药业有限公司 | 负载peg-epo及间充质干细胞的组合物、药物及其制备方法 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ210501A (en) | 1983-12-13 | 1991-08-27 | Kirin Amgen Inc | Erythropoietin produced by procaryotic or eucaryotic expression of an exogenous dna sequence |
| US5166322A (en) | 1989-04-21 | 1992-11-24 | Genetics Institute | Cysteine added variants of interleukin-3 and chemical modifications thereof |
| KR100221066B1 (ko) | 1989-10-13 | 1999-10-01 | 스튜어트 엘.왓트 | 에리트로포이에틴 유사체와 그를 포함하는 제약학적 조성물 |
| CN1057534C (zh) | 1993-08-17 | 2000-10-18 | 柯瑞英-艾格公司 | 促红细胞生成素类似物 |
| TWI240627B (en) | 1996-04-26 | 2005-10-01 | Chugai Pharmaceutical Co Ltd | Erythropoietin solution preparation |
| JP2003225084A (ja) * | 2000-12-28 | 2003-08-12 | Japan Science & Technology Corp | 凍結細胞保存剤 |
| PA8536201A1 (es) * | 2000-12-29 | 2002-08-29 | Kenneth S Warren Inst Inc | Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetina |
| US6531121B2 (en) * | 2000-12-29 | 2003-03-11 | The Kenneth S. Warren Institute, Inc. | Protection and enhancement of erythropoietin-responsive cells, tissues and organs |
| US7767643B2 (en) * | 2000-12-29 | 2010-08-03 | The Kenneth S. Warren Institute, Inc. | Protection, restoration, and enhancement of erythropoietin-responsive cells, tissues and organs |
| ATE542904T1 (de) | 2001-10-29 | 2012-02-15 | Crucell Holland Bv | Verfahren und mittel zur herstellung von proteinen mit vorbestimmten posttranslationalen modifikationen |
| US7468242B2 (en) * | 2001-11-05 | 2008-12-23 | Medgenics, Inc. | Dermal micro organs, methods and apparatuses for producing and using the same |
| DE10234192B4 (de) * | 2002-07-26 | 2009-11-26 | Epoplus Gmbh Co.Kg | Verwendung von Erythropoetin |
| WO2004022545A1 (ja) | 2002-09-06 | 2004-03-18 | Mitsubishi Pharma Corporation | 移植臓器保護剤 |
| US7459152B2 (en) * | 2003-04-23 | 2008-12-02 | Rush University Medical Center | Erythropoietin administration to improve graft survival |
| EP2377402A1 (en) * | 2003-05-01 | 2011-10-19 | Medgenics, Inc. | A genetically modified dermal micro-organ expressing interferon |
| ES2346226T3 (es) * | 2003-12-30 | 2010-10-13 | Augustinus Bader | Uso de la eritropoyetina para la regeneracion de tejido hepatico. |
| JP2005350363A (ja) | 2004-06-08 | 2005-12-22 | Kyorin Pharmaceut Co Ltd | ヘムオキシゲナーゼの誘導または誘導促進剤としての４−トリフルオロメチルピリミジン誘導体 |
| JP2005350364A (ja) | 2004-06-08 | 2005-12-22 | Kyorin Pharmaceut Co Ltd | ヘムオキシゲナーゼの誘導または誘導促進剤としてのプロリン誘導体 |
| DE602005014117D1 (de) * | 2004-07-07 | 2009-06-04 | Lundbeck As Valby H | Neues carbamyliertes epo und verfahren zu dessen herstellung |
-
2008
- 2008-03-06 AR ARP080100920A patent/AR065613A1/es unknown
- 2008-03-07 JP JP2009504020A patent/JP5763882B2/ja active Active
- 2008-03-07 PE PE2008000439A patent/PE20081879A1/es not_active Application Discontinuation
- 2008-03-07 EP EP08721551A patent/EP2143439A4/en not_active Withdrawn
- 2008-03-07 WO PCT/JP2008/054133 patent/WO2008111503A1/ja active Application Filing
- 2008-03-07 CN CN200880007755A patent/CN101631561A/zh active Pending
- 2008-03-07 CL CL200800701A patent/CL2008000701A1/es unknown
- 2008-03-07 TW TW097108127A patent/TW200904825A/zh unknown
- 2008-03-07 US US12/530,491 patent/US20100137191A1/en not_active Abandoned
- 2008-03-07 CA CA002680236A patent/CA2680236A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| PE20081879A1 (es) | 2009-01-10 |
| EP2143439A1 (en) | 2010-01-13 |
| JP5763882B2 (ja) | 2015-08-12 |
| JPWO2008111503A1 (ja) | 2010-06-24 |
| WO2008111503A1 (ja) | 2008-09-18 |
| CA2680236A1 (en) | 2008-09-18 |
| US20100137191A1 (en) | 2010-06-03 |
| CL2008000701A1 (es) | 2008-09-12 |
| EP2143439A4 (en) | 2011-06-29 |
| TW200904825A (en) | 2009-02-01 |
| CN101631561A (zh) | 2010-01-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FB | Suspension of granting procedure |