EP4249001A3 - Gels topiques - Google Patents
Gels topiques Download PDFInfo
- Publication number
- EP4249001A3 EP4249001A3 EP23188645.8A EP23188645A EP4249001A3 EP 4249001 A3 EP4249001 A3 EP 4249001A3 EP 23188645 A EP23188645 A EP 23188645A EP 4249001 A3 EP4249001 A3 EP 4249001A3
- Authority
- EP
- European Patent Office
- Prior art keywords
- topical gels
- topical
- gels
- wounds
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000499 gel Substances 0.000 title abstract 3
- 230000000699 topical effect Effects 0.000 title abstract 3
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 abstract 2
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/80—Polymers containing hetero atoms not provided for in groups A61K31/755 - A61K31/795
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/655—Azo (—N=N—), diazo (=N2), azoxy (>N—O—N< or N(=O)—N<), azido (—N3) or diazoamino (—N=N—N<) compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6903—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being semi-solid, e.g. an ointment, a gel, a hydrogel or a solidifying gel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/44—Medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
- A61L15/60—Liquid-swellable gel-forming materials, e.g. super-absorbents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Hematology (AREA)
- Materials Engineering (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Inorganic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23593309P | 2009-08-21 | 2009-08-21 | |
| PCT/US2010/046173 WO2011022652A1 (fr) | 2009-08-21 | 2010-08-20 | Gels topiques |
| EP10747132.8A EP2467127B1 (fr) | 2009-08-21 | 2010-08-20 | Gels topiques |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP10747132.8A Division EP2467127B1 (fr) | 2009-08-21 | 2010-08-20 | Gels topiques |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EP4249001A2 EP4249001A2 (fr) | 2023-09-27 |
| EP4249001A3 true EP4249001A3 (fr) | 2023-11-29 |
Family
ID=43067010
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP23188645.8A Pending EP4249001A3 (fr) | 2009-08-21 | 2010-08-20 | Gels topiques |
| EP10747132.8A Active EP2467127B1 (fr) | 2009-08-21 | 2010-08-20 | Gels topiques |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EP10747132.8A Active EP2467127B1 (fr) | 2009-08-21 | 2010-08-20 | Gels topiques |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US9526738B2 (fr) |
| EP (2) | EP4249001A3 (fr) |
| CN (1) | CN102711729B (fr) |
| BR (1) | BR112012003792B1 (fr) |
| CA (2) | CA3062005C (fr) |
| ES (1) | ES2958410T3 (fr) |
| WO (1) | WO2011022652A1 (fr) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE429255T1 (de) | 2005-03-24 | 2009-05-15 | Nolabs Ab | Kosmetische behandlung mit stickoxid, vorrichtung zur durchführung dieser behandlung und herstellungsverfahren dafür |
| ES2731298T3 (es) | 2005-05-27 | 2019-11-14 | Univ North Carolina Chapel Hill | Partículas de liberación de óxido nítrico para agentes terapéuticos de óxido nítrico y aplicaciones biomédicas |
| GB2463181B (en) | 2007-05-14 | 2013-03-27 | Univ New York State Res Found | Induction of a physiological dispersion response in bacterial cells in a biofilm |
| EP4249001A3 (fr) | 2009-08-21 | 2023-11-29 | Novan, Inc. | Gels topiques |
| US8591876B2 (en) * | 2010-12-15 | 2013-11-26 | Novan, Inc. | Methods of decreasing sebum production in the skin |
| EP2665763B1 (fr) | 2011-01-20 | 2015-08-26 | Novan, Inc. | Co-condensation de sol-gel à température contrôlée |
| WO2012158448A2 (fr) * | 2011-05-13 | 2012-11-22 | Quadsil, Inc. | Compositions comprenant un polymère siloxane |
| BR112014000178A2 (pt) | 2011-07-05 | 2017-02-07 | Novan Inc | composições tópicas |
| WO2013006613A1 (fr) | 2011-07-05 | 2013-01-10 | Novan, Inc. | Procédés de fabrication de compositions topiques et appareil afférent |
| WO2013029009A1 (fr) | 2011-08-24 | 2013-02-28 | Novan, Inc. | Macromolécules libérant de l'oxyde nitrique ajustables possédant plusieurs structures donneuses d'oxyde nitrique |
| WO2013052958A2 (fr) * | 2011-10-08 | 2013-04-11 | Microbial Defense Systems, Llc | Compositions antimicrobiennes et procédés les utilisant |
| US9592241B2 (en) | 2011-12-27 | 2017-03-14 | Cmpd Licensing, Llc | Silicone-based composition for skin treatment |
| EP2833721B1 (fr) * | 2012-03-14 | 2021-02-17 | Novan Inc. | Compositions pharmaceutiques libérant de l'oxyde nitrique |
| US9855211B2 (en) * | 2013-02-28 | 2018-01-02 | Novan, Inc. | Topical compositions and methods of using the same |
| WO2014179754A2 (fr) | 2013-05-02 | 2014-11-06 | Next Science, Llc | Composition antimicrobienne à haute osmolarité contenant un ou plusieurs solvants organiques |
| CA2920110C (fr) * | 2013-08-08 | 2022-05-31 | Novan, Inc. | Compositions et trousses y compris les composes liberant de l'oxyde nitrique et un hydrogene |
| US9226890B1 (en) | 2013-12-10 | 2016-01-05 | Englewood Lab, Llc | Polysilicone base for scar treatment |
| JP6568534B2 (ja) * | 2014-01-27 | 2019-08-28 | ユニリーバー・ナームローゼ・ベンノートシヤープ | 組成物 |
| WO2015189712A2 (fr) * | 2014-06-09 | 2015-12-17 | Klox Technologies Inc. | Compositions biophotoniques à base de silicone et leurs utilisations |
| US10322082B2 (en) | 2014-07-11 | 2019-06-18 | Novan, Inc. | Topical antiviral compositions and methods of using the same |
| BR112017000456B1 (pt) * | 2014-07-11 | 2022-12-13 | Novan, Inc | Uso de um ingrediente farmacêutico ativo de liberação de óxido nítrico e composição tópica para tratamento e/ou prevenção de uma infecção viral |
| US10925689B2 (en) | 2014-07-14 | 2021-02-23 | Novan, Inc. | Nitric oxide releasing nail coating compositions, nitric oxide releasing nail coatings, and methods of using the same |
| CA2919733A1 (fr) * | 2014-08-08 | 2016-02-08 | Novan, Inc. | Compositions topiques et methodes d'utilisation desdites compositions |
| RU2753125C2 (ru) * | 2015-07-02 | 2021-08-11 | Аобиом Ллк | Окисляющие аммиак бактерии для лечения угревой сыпи |
| AU2016342092B2 (en) | 2015-07-17 | 2020-09-10 | Next Science IP Holdings Pty Ltd | Antimicrobial composition having efficacy against endospores |
| US10849864B2 (en) | 2015-07-28 | 2020-12-01 | Novan, Inc. | Combinations and methods for the treatment and/or prevention of fungal infections |
| RU2018113280A (ru) | 2015-09-16 | 2019-10-16 | ДиЭфБи СОРИА, ЭлЭлСи | Доставка наночастиц лекарственного средства и способы их использования |
| TWI607067B (zh) * | 2015-09-25 | 2017-12-01 | 立得光電科技股份有限公司 | 抗菌、防霉的表面塗料及其製作方法 |
| KR102319497B1 (ko) | 2016-03-02 | 2021-11-01 | 노반, 인크. | 염증 치료용 조성물 및 염증 치료 방법 |
| EP3442502A4 (fr) * | 2016-04-13 | 2019-11-06 | Novan, Inc. | Compositions, systèmes, kits et méthodes pour traiter une infection |
| CN105832656B (zh) * | 2016-05-25 | 2018-10-09 | 暨南大学 | 一种载一氧化氮的羧化壳聚糖-聚乙烯亚胺水凝胶及其制备方法和应用 |
| WO2018170207A1 (fr) * | 2017-03-15 | 2018-09-20 | Dfb Soria, Llc | Thérapie topique pour le traitement de kératoses cutanées à l'aide de nanoparticules de taxanes |
| CA3056395C (fr) | 2017-03-15 | 2022-06-28 | Dfb Soria, Llc | Therapie topique pour le traitement de malignites cutanees au moyen de nanoparticules de taxanes |
| CN110799203A (zh) * | 2017-04-21 | 2020-02-14 | Phi治疗股份有限公司 | 用于治疗痤疮的包含痤疮丙酸杆菌噬菌体的组合物 |
| WO2018236803A1 (fr) | 2017-06-19 | 2018-12-27 | Novan, Inc. | Compositions topiques et leurs procédés d'utilisation |
| WO2019114705A1 (fr) | 2017-12-13 | 2019-06-20 | 上海小午医药科技有限公司 | Méthode de prévention ou de traitement d'une maladie associée à l'inhibition du récepteur du facteur de croissance épidermique (regf) |
| CN112165935A (zh) | 2018-03-01 | 2021-01-01 | 诺万公司 | 一氧化氮释放性栓剂及其使用方法 |
| US11497726B2 (en) | 2018-03-16 | 2022-11-15 | Dfb Soria, Ll. | Topical therapy for the treatment of cervical intraepithelial neoplasia (CIN) and cervical cancer using nanoparticles of taxanes |
| AU2019254237B2 (en) | 2018-04-16 | 2025-01-30 | Onquality Pharmaceuticals China Ltd. | Method for preventing or treating side effects of cancer therapy |
| WO2019231848A1 (fr) | 2018-05-30 | 2019-12-05 | Morehouse School Of Medicine | Compositions antibactériennes, leurs procédés de fabrication et d'utilisation |
| US11541105B2 (en) | 2018-06-01 | 2023-01-03 | The Research Foundation For The State University Of New York | Compositions and methods for disrupting biofilm formation and maintenance |
| WO2020074957A1 (fr) * | 2018-10-12 | 2020-04-16 | Sanotize Research And Development Corp. | Compositions à dégagement de gaz et systèmes de récipient et de distribution |
| CN113383019B (zh) * | 2018-12-28 | 2023-11-17 | 北卡罗来纳大学教堂山分校 | 一氧化氮释放型抗菌聚合物和由其制成的支架和其相关方法 |
| US11478417B2 (en) | 2019-04-05 | 2022-10-25 | Aki, Inc. | Fragrance product |
| RU2713943C1 (ru) * | 2019-10-28 | 2020-02-11 | Александр Ливиевич Ураков | Гель для кожи детей |
| US11654057B2 (en) | 2020-04-09 | 2023-05-23 | Bio 54, Llc | Devices for bleeding reduction and methods of making and using the same |
| BR112022020358A2 (pt) | 2020-04-13 | 2022-11-29 | Aki Inc | Produto cosmético sedoso anidro |
| WO2023044467A1 (fr) * | 2021-09-20 | 2023-03-23 | University Of Georgia Research Foundation, Inc. | Polysiloxanes libérant de l'oxyde nitrique et leurs procédés de préparation et d'utilisation |
| US11642324B1 (en) | 2022-03-01 | 2023-05-09 | Bio 54, Llc | Topical tranexamic acid compositions and methods of use thereof |
| WO2023220188A1 (fr) * | 2022-05-11 | 2023-11-16 | The University Of North Carolina At Chapel Hill | Glycosaminoglycanes libérant de l'oxyde nitrique pour la cicatrisation de plaies |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009049208A1 (fr) * | 2007-10-12 | 2009-04-16 | The University Of North Carolina At Chapel Hill | Utilisation d'oxyde nitrique pour amplifier l'efficacité de l'argent et d'autres agents cicatrisants topiques |
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| US4396615A (en) | 1981-06-24 | 1983-08-02 | Duke University | Method of treating androgen-related disorders |
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Also Published As
| Publication number | Publication date |
|---|---|
| CA2771308A1 (fr) | 2011-02-24 |
| EP2467127B1 (fr) | 2023-08-02 |
| EP2467127C0 (fr) | 2023-08-02 |
| US20120134951A1 (en) | 2012-05-31 |
| CN102711729B (zh) | 2015-04-01 |
| WO2011022652A1 (fr) | 2011-02-24 |
| CA3062005A1 (fr) | 2011-02-24 |
| US20170312307A1 (en) | 2017-11-02 |
| CA3062005C (fr) | 2022-02-15 |
| BR112012003792B1 (pt) | 2020-05-19 |
| ES2958410T3 (es) | 2024-02-08 |
| US10376538B2 (en) | 2019-08-13 |
| US9526738B2 (en) | 2016-12-27 |
| CN102711729A (zh) | 2012-10-03 |
| CA2771308C (fr) | 2020-01-21 |
| US9737561B2 (en) | 2017-08-22 |
| US20170056437A1 (en) | 2017-03-02 |
| EP2467127A1 (fr) | 2012-06-27 |
| EP4249001A2 (fr) | 2023-09-27 |
| BR112012003792A2 (pt) | 2016-04-19 |
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