CA2403818A1 - Matrices renfermant des donneurs d'oxyde nitrique ainsi que des agents reducteurs et leur utilisation - Google Patents
Matrices renfermant des donneurs d'oxyde nitrique ainsi que des agents reducteurs et leur utilisation Download PDFInfo
- Publication number
- CA2403818A1 CA2403818A1 CA002403818A CA2403818A CA2403818A1 CA 2403818 A1 CA2403818 A1 CA 2403818A1 CA 002403818 A CA002403818 A CA 002403818A CA 2403818 A CA2403818 A CA 2403818A CA 2403818 A1 CA2403818 A1 CA 2403818A1
- Authority
- CA
- Canada
- Prior art keywords
- nitric oxide
- matrix
- composition
- donor
- oxide donor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- HYHSBSXUHZOYLX-WDSKDSINSA-N S-nitrosoglutathione Chemical group OC(=O)[C@@H](N)CCC(=O)N[C@@H](CSN=O)C(=O)NCC(O)=O HYHSBSXUHZOYLX-WDSKDSINSA-N 0.000 claims description 24
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
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Landscapes
- Health & Medical Sciences (AREA)
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Abstract
Cette composition, qui comprend une matrice hydrophobe, un donneur d'oxyde nitrique (NO) susceptible d'être réduit ainsi qu'un agent réducteur intrinsèque associé au donneur de NO dans la matrice, libère de la matrice une quantité efficace de NO après humectation à un pH physiologique, indépendamment de la présence ou de l'absence d'agents réducteurs extrinsèques. Cette composition inhibe la croissance de cellules cibles dans un milieu cible.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19054600P | 2000-03-20 | 2000-03-20 | |
| US19057100P | 2000-03-20 | 2000-03-20 | |
| US60/190,571 | 2000-03-20 | ||
| US60/190,546 | 2000-03-20 | ||
| PCT/US2001/008806 WO2001070199A1 (fr) | 2000-03-20 | 2001-03-20 | Matrices renfermant des donneurs d'oxyde nitrique ainsi que des agents reducteurs et leur utilisation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2403818A1 true CA2403818A1 (fr) | 2001-09-27 |
Family
ID=26886210
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002403818A Abandoned CA2403818A1 (fr) | 2000-03-20 | 2001-03-20 | Matrices renfermant des donneurs d'oxyde nitrique ainsi que des agents reducteurs et leur utilisation |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1267837A4 (fr) |
| JP (1) | JP2003527209A (fr) |
| AU (2) | AU4757901A (fr) |
| CA (1) | CA2403818A1 (fr) |
| IL (1) | IL151604A0 (fr) |
| MX (1) | MXPA02009236A (fr) |
| WO (1) | WO2001070199A1 (fr) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7678391B2 (en) | 2000-04-26 | 2010-03-16 | Queen's University At Kingston | Formulations and methods of using nitric oxide mimetics against a malignant cell phenotype |
| ES2232613T3 (es) | 2000-04-26 | 2005-06-01 | Cellegy Pharmaceuticals, Inc | Formulaciones y metodos de utilizacion de agentes mimeticos del oxido nitrico contra un fenotipo celular maligno. |
| US7700819B2 (en) | 2001-02-16 | 2010-04-20 | Kci Licensing, Inc. | Biocompatible wound dressing |
| US7763769B2 (en) | 2001-02-16 | 2010-07-27 | Kci Licensing, Inc. | Biocompatible wound dressing |
| US7135189B2 (en) | 2001-08-23 | 2006-11-14 | Boston Scientific Scimed, Inc. | Compositions and techniques for localized therapy |
| US7972137B2 (en) * | 2003-06-30 | 2011-07-05 | Rosen Gerald M | Anti-microbial dental formulations for the prevention and treatment of oral mucosal disease |
| WO2006128121A2 (fr) | 2005-05-27 | 2006-11-30 | The University Of North Carolina At Chapel Hill | Particules liberant de l'oxyde nitrique pour therapie a base d'oxyde nitrique et applications biomedicales |
| EP1968664B1 (fr) * | 2005-12-02 | 2010-10-27 | The Regents Of The University Of Michigan | Compositions polymeres, revetements et dispositifs, et procedes de fabrication et d'utilisation de ceux-ci |
| US11229746B2 (en) | 2006-06-22 | 2022-01-25 | Excelsior Medical Corporation | Antiseptic cap |
| US9259535B2 (en) | 2006-06-22 | 2016-02-16 | Excelsior Medical Corporation | Antiseptic cap equipped syringe |
| HU0800031D0 (en) * | 2008-01-16 | 2008-03-28 | Biotech Hungary Kutato Es Fejl | Method for stabilization of s-nitrosoglutathione and composition prepared by the same |
| US9078992B2 (en) | 2008-10-27 | 2015-07-14 | Pursuit Vascular, Inc. | Medical device for applying antimicrobial to proximal end of catheter |
| US20100233288A1 (en) * | 2009-03-11 | 2010-09-16 | Teleflex Medical Incorporated | Medical devices containing nitroprusside and antimicrobial agents |
| US11219706B2 (en) | 2009-03-11 | 2022-01-11 | Arrow International Llc | Enhanced formulations for coating medical devices |
| CN102711729B (zh) | 2009-08-21 | 2015-04-01 | 诺万公司 | 局部用凝胶 |
| US9919072B2 (en) | 2009-08-21 | 2018-03-20 | Novan, Inc. | Wound dressings, methods of using the same and methods of forming the same |
| US8591876B2 (en) | 2010-12-15 | 2013-11-26 | Novan, Inc. | Methods of decreasing sebum production in the skin |
| EP2681286B1 (fr) | 2011-02-28 | 2018-08-15 | Novan, Inc. | Particules de silice modifiées par des groupements s-nitrosothiols libérant de l'oxyde nitrique et procédés de fabrication associés |
| US10166381B2 (en) | 2011-05-23 | 2019-01-01 | Excelsior Medical Corporation | Antiseptic cap |
| EP2731658B1 (fr) | 2011-07-12 | 2020-04-01 | Pursuit Vascular, Inc. | Dispositif de distribution d'agent antimicrobien dans cathéter transdermique |
| JP2016514171A (ja) * | 2013-02-07 | 2016-05-19 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | Ｓ−ニトロソ−ｎ−アセチルペニシラミン（ｓｎａｐ）をドープした安定性の向上した血栓形成抵抗性／殺菌性の酸化窒素放出性ポリマー |
| EP3137122B1 (fr) | 2014-05-02 | 2019-09-04 | Excelsior Medical Corporation | Emballage de bande pour bouchon antiseptique |
| CA2982456A1 (fr) | 2015-05-08 | 2016-11-17 | Icu Medical, Inc. | Raccords medicaux configures pour recevoir des emetteurs d'agents therapeutiques |
| US10744316B2 (en) | 2016-10-14 | 2020-08-18 | Icu Medical, Inc. | Sanitizing caps for medical connectors |
| CN110446521B (zh) | 2017-01-21 | 2022-05-06 | 生物克瑞德公司 | 配置用于一氧化氮的控制释放的医疗产品和方法 |
| WO2018204206A2 (fr) | 2017-05-01 | 2018-11-08 | Icu Medical, Inc. | Raccords de fluide médical et procédés pour fournir des additifs dans des conduites de fluide médical |
| CN107823644B (zh) * | 2017-11-07 | 2021-03-02 | 福州大学 | 一种no供体化合物在制备抑制富含巯基分子的肿瘤细胞的侵袭和转移能力药物中的应用 |
| US11534595B2 (en) | 2018-11-07 | 2022-12-27 | Icu Medical, Inc. | Device for delivering an antimicrobial composition into an infusion device |
| US11400195B2 (en) | 2018-11-07 | 2022-08-02 | Icu Medical, Inc. | Peritoneal dialysis transfer set with antimicrobial properties |
| US11541220B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Needleless connector with antimicrobial properties |
| US11517732B2 (en) | 2018-11-07 | 2022-12-06 | Icu Medical, Inc. | Syringe with antimicrobial properties |
| US11541221B2 (en) | 2018-11-07 | 2023-01-03 | Icu Medical, Inc. | Tubing set with antimicrobial properties |
| US11433215B2 (en) | 2018-11-21 | 2022-09-06 | Icu Medical, Inc. | Antimicrobial device comprising a cap with ring and insert |
| EP4255552A1 (fr) | 2020-12-07 | 2023-10-11 | ICU Medical, Inc. | Capuchons, systèmes et procédés de dialyse péritonéale |
| CN114868846A (zh) * | 2022-04-25 | 2022-08-09 | 闽江学院 | 外源性一氧化氮供体gsno作为饲料添加剂的应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5770645A (en) * | 1996-08-02 | 1998-06-23 | Duke University Medical Center | Polymers for delivering nitric oxide in vivo |
| US5797887A (en) * | 1996-08-27 | 1998-08-25 | Novovasc Llc | Medical device with a surface adapted for exposure to a blood stream which is coated with a polymer containing a nitrosyl-containing organo-metallic compound which releases nitric oxide from the coating to mediate platelet aggregation |
| WO1998043621A1 (fr) * | 1997-03-31 | 1998-10-08 | The Children's Medical Center Corporation | Nitrosylation effectuee pour inactiver des enzymes apoptotiques |
| US6171232B1 (en) * | 1997-06-26 | 2001-01-09 | Cordis Corporation | Method for targeting in vivo nitric oxide release |
| IL121527A0 (en) * | 1997-08-12 | 1998-02-08 | U E T Ltd | Heating systems based on alternating-current electrodes |
| US5994444A (en) * | 1997-10-16 | 1999-11-30 | Medtronic, Inc. | Polymeric material that releases nitric oxide |
| US6093743A (en) * | 1998-06-23 | 2000-07-25 | Medinox Inc. | Therapeutic methods employing disulfide derivatives of dithiocarbamates and compositions useful therefor |
| US6207855B1 (en) * | 1998-06-23 | 2001-03-27 | Duke University Medical Center | Stable no-delivering compounds |
-
2001
- 2001-03-20 CA CA002403818A patent/CA2403818A1/fr not_active Abandoned
- 2001-03-20 MX MXPA02009236A patent/MXPA02009236A/es unknown
- 2001-03-20 IL IL15160401A patent/IL151604A0/xx unknown
- 2001-03-20 WO PCT/US2001/008806 patent/WO2001070199A1/fr active IP Right Grant
- 2001-03-20 AU AU4757901A patent/AU4757901A/xx active Pending
- 2001-03-20 AU AU2001247579A patent/AU2001247579B2/en not_active Ceased
- 2001-03-20 JP JP2001568397A patent/JP2003527209A/ja active Pending
- 2001-03-20 EP EP01920538A patent/EP1267837A4/fr not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| AU4757901A (en) | 2001-10-03 |
| IL151604A0 (en) | 2003-04-10 |
| MXPA02009236A (es) | 2004-04-05 |
| EP1267837A1 (fr) | 2003-01-02 |
| EP1267837A4 (fr) | 2006-05-03 |
| AU2001247579B2 (en) | 2005-01-06 |
| WO2001070199A1 (fr) | 2001-09-27 |
| JP2003527209A (ja) | 2003-09-16 |
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