EE9800065A - 5-O-desosaminüül-6-O-metüülerütronoliid A uued derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete produktide valmistamiseks - Google Patents

5-O-desosaminüül-6-O-metüülerütronoliid A uued derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete produktide valmistamiseks

Info

Publication number: EE9800065A
Authority: EE; Estonia
Prior art keywords: preparation; methylerythronolide; desosaminyl; new derivatives; bioactive products
Prior art date: 1995-09-11

Application number

EE9800065A

Other languages

English (en)

Other versions

EE03774B1 (et

Inventor

Bonnet Alain

Delthil Michel

Mazurie Alain

Original Assignee

Hoechst Marion Roussel

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-09-11

Filing date

1996-09-10

Publication date

1998-08-17

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9482423&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE9800065(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-09-10 Application filed by Hoechst Marion Roussel filed Critical Hoechst Marion Roussel

1998-08-17 Publication of EE9800065A publication Critical patent/EE9800065A/et

2002-06-17 Publication of EE03774B1 publication Critical patent/EE03774B1/et

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Life Sciences & Earth Sciences (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

EE9800065A 1995-09-11 1996-09-10 5-O-desosaminüül-6-O-metüülerütronoliid A derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete produktide valmistamiseks EE03774B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9510601A FR2738571B1 (fr)	1995-09-11	1995-09-11	Nouveaux derives de la 5-0-desosaminyl 6-0-methyl- erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
PCT/FR1996/001384 WO1997010251A1 (fr)	1995-09-11	1996-09-10	Nouveaux derives de la 5-0-desosaminyl 6-0-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs

Publications (2)

Publication Number	Publication Date
EE9800065A true EE9800065A (et)	1998-08-17
EE03774B1 EE03774B1 (et)	2002-06-17

Family

ID=9482423

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EE9800065A EE03774B1 (et)	1995-09-11	1996-09-10	5-O-desosaminüül-6-O-metüülerütronoliid A derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete produktide valmistamiseks

Country Status (34)

Country	Link
US (1)	US5969161A (et)
EP (1)	EP0854880B1 (et)
JP (1)	JP4332218B2 (et)
KR (1)	KR100457755B1 (et)
CN (2)	CN1237069C (et)
AP (1)	AP887A (et)
AR (1)	AR004195A1 (et)
AT (1)	ATE266035T1 (et)
AU (1)	AU708811B2 (et)
BG (1)	BG63822B1 (et)
BR (1)	BR9610503A (et)
CA (1)	CA2228670C (et)
CZ (3)	CZ294866B6 (et)
DE (1)	DE69632405T2 (et)
DK (1)	DK0854880T3 (et)
EA (1)	EA000575B1 (et)
EE (1)	EE03774B1 (et)
ES (1)	ES2219698T3 (et)
FR (1)	FR2738571B1 (et)
GE (1)	GEP20022838B (et)
HK (2)	HK1016187A1 (et)
HU (1)	HU227565B1 (et)
IL (1)	IL123550A (et)
MX (1)	MX9801859A (et)
NO (2)	NO312678B1 (et)
PL (1)	PL183652B1 (et)
PT (1)	PT854880E (et)
RO (1)	RO120137B1 (et)
SI (1)	SI0854880T1 (et)
SK (3)	SK285995B6 (et)
TR (1)	TR199800438T1 (et)
UA (1)	UA53628C2 (et)
WO (1)	WO1997010251A1 (et)
ZA (1)	ZA966837B (et)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA51730C2 (uk) *	1996-09-04	2002-12-16	Ебботт Лабораторіз	6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
JP4597274B2 (ja) *	1996-09-04	2010-12-15	アボット・ラボラトリーズ	抗菌活性を有する６―ｏ―置換ケトリド
US6034069A (en) *	1997-09-30	2000-03-07	Abbott Laboratories	3-'N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity
US6124269A (en) *	1997-10-29	2000-09-26	Abbott Laboratories	2-Halo-6-O-substituted ketolide derivatives
US6046171A (en) *	1997-10-29	2000-04-04	Abbott Laboratories	6,11-bridged erythromycin derivatives
US6054435A (en) *	1999-03-19	2000-04-25	Abbott Laboratories	6-O-substituted macrolides having antibacterial activity
US6420535B1 (en)	1999-06-07	2002-07-16	Abbott Laboratories	6-O-carbamate ketolide derivatives
WO2003070174A2 (en) *	2002-02-15	2003-08-28	Sympore Gmbh	Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
US7022679B2 (en) *	2002-05-13	2006-04-04	Enanta Pharmaceuticals, Inc.	Processes for the preparation of 6-11 bicyclic erythromycin derivatives
US6764998B1 (en)	2003-06-18	2004-07-20	Enanta Pharmaceuticals, Inc.	6,11-4C-bicyclic 9a-azalide derivatives
US6878691B2 (en) *	2002-05-13	2005-04-12	Enanta Pharmaceuticals, Inc.	6-11 bicyclic ketolide derivatives
US7135573B2 (en) *	2002-05-13	2006-11-14	Enanta Pharmaceuticals, Inc.	Processes for the preparation of O-(6-Pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine
US6753318B1 (en) *	2002-07-25	2004-06-22	Enanta Pharmaceuticals, Inc.	6,11-4-carbon bridged erythromycin derivatives
KR100661973B1 (ko) *	2002-05-13	2006-12-28	이난타 파마슈티칼스, 인코포레이티드	6,11 바이사이클릭 에리스로마이신 유도체
US6841664B2 (en) *	2002-07-25	2005-01-11	Enanra Pharmaceuticals, Inc.	6,11-4-carbon bridged ketolides
US7910558B2 (en) *	2002-05-13	2011-03-22	Enanta Pharmaceuticals, Inc.	Bridged macrocyclic compounds and processes for the preparation thereof
US7064110B2 (en) *	2002-05-13	2006-06-20	Enanta Pharmaceuticals, Inc.	6-11 bicycle ketolide derivatives
US7273853B2 (en) *	2002-05-13	2007-09-25	Enanta Pharmaceuticals, Inc.	6-11 bicyclic ketolide derivatives
ITMI20021726A1 (it) *	2002-08-01	2004-02-02	Zambon Spa	Macrolidi ad attivita' antiinfiammatoria.
US6645941B1 (en)	2003-03-26	2003-11-11	Enanta Pharmaceuticals, Inc.	6,11-3C-bicyclic 9a-azalide derivatives
WO2005030227A1 (en) *	2003-09-23	2005-04-07	Enanta Pharmaceuticals, Inc.	9a, 11-3C-BICYCLIC 9a-AZALIDE DERIVATIVES
US7414030B2 (en) *	2004-01-07	2008-08-19	Enanta Pharmaceuticals, Inc.	6-11 Bicyclic erythromycin derivatives
WO2005070113A2 (en) *	2004-01-09	2005-08-04	Enanta Pharmaceuticals, Inc.	9n-substituted 6-11 bicyclic erythromycin derivatives
US7229972B2 (en)	2004-12-07	2007-06-12	Enanta Pharmaceuticals, Inc.	3,6-Bicyclolides
US7419962B2 (en)	2004-12-07	2008-09-02	Enanta Pharmaceuticals, Inc.	3,6-bicyclolides
WO2006065721A2 (en)	2004-12-13	2006-06-22	Enanta Pharmaceuticals, Inc.	11, 12-lactone bicyclolides
US7312201B2 (en)	2004-12-13	2007-12-25	Enanta Pharmaceuticals, Inc.	Tetracyclic bicyclolides
US7384922B2 (en) *	2005-05-04	2008-06-10	Enanta Pharmaceuticals, Inc.	6-11 bridged oxime erythromycin derivatives
RU2008106915A (ru) *	2005-07-26	2009-09-10	Меркле Гмбх (De)	Макролидные конъюгаты пирролиновых и индолизиновых соединений
CN101855219B (zh) *	2007-09-17	2014-06-25	英安塔制药有限公司	6，11-桥联的联芳大环内酯类
US8354383B2 (en) *	2007-09-17	2013-01-15	Enanta Pharmaceuticals, Inc.	6,11-bridged biaryl macrolides
US8273720B2 (en) *	2007-09-17	2012-09-25	Enanta Pharmaceuticals, Inc.	6,11-bicyclolides: bridged biaryl macrolide derivatives
CN103232501A (zh) *	2013-04-11	2013-08-07	宜昌东阳光药业股份有限公司	阿奇霉素或阿奇霉素的中间体脱去克拉定糖化合物的制备工艺

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR960000434B1 (ko) *	1986-12-17	1996-01-06	다이쇼 세이야꾸 가부시끼가이샤	에리스로마이신 a유도체 및 그의 제조 방법
US5523399A (en) *	1991-12-27	1996-06-04	Taisho Pharmaceutical Co., Ltd.	5-O-desosaminylerythronolide derivatives

1995
- 1995-09-11 FR FR9510601A patent/FR2738571B1/fr not_active Expired - Lifetime
1996
- 1996-08-13 ZA ZA9606837A patent/ZA966837B/xx unknown
- 1996-09-05 AR ARP960104239A patent/AR004195A1/es unknown
- 1996-09-10 SK SK892-2003A patent/SK285995B6/sk not_active IP Right Cessation
- 1996-09-10 PT PT96931098T patent/PT854880E/pt unknown
- 1996-09-10 AT AT96931098T patent/ATE266035T1/de active
- 1996-09-10 SK SK294-98A patent/SK283690B6/sk not_active IP Right Cessation
- 1996-09-10 CA CA002228670A patent/CA2228670C/fr not_active Expired - Lifetime
- 1996-09-10 CN CNB001309064A patent/CN1237069C/zh not_active Expired - Lifetime
- 1996-09-10 KR KR10-1998-0701791A patent/KR100457755B1/ko not_active IP Right Cessation
- 1996-09-10 CN CN96198171A patent/CN1070498C/zh not_active Expired - Lifetime
- 1996-09-10 GE GEAP19964228A patent/GEP20022838B/en unknown
- 1996-09-10 RO RO98-00685A patent/RO120137B1/ro unknown
- 1996-09-10 PL PL96326274A patent/PL183652B1/pl unknown
- 1996-09-10 HU HU9802930A patent/HU227565B1/hu unknown
- 1996-09-10 WO PCT/FR1996/001384 patent/WO1997010251A1/fr active IP Right Grant
- 1996-09-10 EP EP96931098A patent/EP0854880B1/fr not_active Expired - Lifetime
- 1996-09-10 AP APAP/P/1998/001210A patent/AP887A/en active
- 1996-09-10 SI SI9630684T patent/SI0854880T1/xx unknown
- 1996-09-10 ES ES96931098T patent/ES2219698T3/es not_active Expired - Lifetime
- 1996-09-10 IL IL12355096A patent/IL123550A/en not_active IP Right Cessation
- 1996-09-10 CZ CZ20012390A patent/CZ294866B6/cs not_active IP Right Cessation
- 1996-09-10 AU AU69910/96A patent/AU708811B2/en not_active Expired
- 1996-09-10 JP JP51169697A patent/JP4332218B2/ja not_active Expired - Lifetime
- 1996-09-10 BR BR9610503A patent/BR9610503A/pt not_active IP Right Cessation
- 1996-09-10 DK DK96931098T patent/DK0854880T3/da active
- 1996-09-10 TR TR1998/00438T patent/TR199800438T1/xx unknown
- 1996-09-10 SK SK893-2003A patent/SK285853B6/sk not_active IP Right Cessation
- 1996-09-10 EA EA199800288A patent/EA000575B1/ru not_active IP Right Cessation
- 1996-09-10 EE EE9800065A patent/EE03774B1/et unknown
- 1996-09-10 US US09/043,044 patent/US5969161A/en not_active Expired - Lifetime
- 1996-09-10 CZ CZ20012389A patent/CZ294865B6/cs not_active IP Right Cessation
- 1996-09-10 DE DE69632405T patent/DE69632405T2/de not_active Expired - Lifetime
- 1996-09-10 CZ CZ1998717A patent/CZ289945B6/cs not_active IP Right Cessation
- 1996-10-09 UA UA98041835A patent/UA53628C2/uk unknown
1998
- 1998-03-09 MX MX9801859A patent/MX9801859A/es unknown
- 1998-03-10 NO NO19981053A patent/NO312678B1/no not_active IP Right Cessation
- 1998-03-10 BG BG102312A patent/BG63822B1/bg unknown
1999
- 1999-03-12 HK HK99101038A patent/HK1016187A1/xx not_active IP Right Cessation
2002
- 2002-03-06 NO NO20021111A patent/NO315048B1/no not_active IP Right Cessation
- 2002-04-19 HK HK02103101.8A patent/HK1041489B/zh not_active IP Right Cessation

Also Published As

Publication number	Publication date
BR9610503A (pt)	1999-07-06
DK0854880T3 (da)	2004-08-16
BG102312A (en)	1998-09-30
ES2219698T3 (es)	2004-12-01
US5969161A (en)	1999-10-19
BG63822B1 (bg)	2003-02-28
JPH11512416A (ja)	1999-10-26
HUP9802930A3 (en)	1999-12-28
EE03774B1 (et)	2002-06-17
IL123550A (en)	2002-09-12
NO981053L (no)	1998-03-10
HU227565B1 (en)	2011-08-29
AP9801210A0 (en)	1998-03-31
SI0854880T1 (en)	2004-12-31
HK1041489A1 (en)	2002-07-12
KR100457755B1 (ko)	2005-02-28
SK283690B6 (sk)	2003-12-02
NO20021111L (no)	1998-03-10
RO120137B1 (ro)	2005-09-30
CZ294866B6 (cs)	2005-04-13
PL183652B1 (pl)	2002-06-28
CN1070498C (zh)	2001-09-05
ZA966837B (en)	1997-08-13
EP0854880B1 (fr)	2004-05-06
CN1201462A (zh)	1998-12-09
CA2228670A1 (fr)	1997-03-20
GEP20022838B (en)	2002-11-25
KR19990044543A (ko)	1999-06-25
UA53628C2 (uk)	2003-02-17
HK1041489B (zh)	2006-09-08
SK29498A3 (en)	1998-12-02
WO1997010251A1 (fr)	1997-03-20
DE69632405D1 (de)	2004-06-09
JP4332218B2 (ja)	2009-09-16
AR004195A1 (es)	1998-11-04
NO981053D0 (no)	1998-03-10
CA2228670C (fr)	2005-04-12
CZ71798A3 (cs)	1998-07-15
CZ294865B6 (cs)	2005-04-13
HUP9802930A1 (hu)	1999-04-28
EP0854880A1 (fr)	1998-07-29
AP887A (en)	2000-11-10
FR2738571B1 (fr)	1997-10-17
NO312678B1 (no)	2002-06-17
AU6991096A (en)	1997-04-01
FR2738571A1 (fr)	1997-03-14
CZ289945B6 (cs)	2002-04-17
ATE266035T1 (de)	2004-05-15
AU708811B2 (en)	1999-08-12
NO20021111D0 (no)	2002-03-06
IL123550A0 (en)	1998-10-30
PL326274A1 (en)	1998-08-31
PT854880E (pt)	2004-09-30
SK285995B6 (sk)	2008-01-07
CN1319602A (zh)	2001-10-31
MX9801859A (es)	1998-11-30
TR199800438T1 (xx)	1998-05-21
NO315048B1 (no)	2003-06-30
EA199800288A1 (ru)	1998-08-27
HK1016187A1 (en)	1999-10-29
DE69632405T2 (de)	2005-05-19
EA000575B1 (ru)	1999-12-29
SK285853B6 (sk)	2007-09-06
CN1237069C (zh)	2006-01-18

Publication	Publication Date	Title
EE9800065A (et)	1998-08-17	5-O-desosaminüül-6-O-metüülerütronoliid A uued derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete produktide valmistamiseks
EE03482B1 (et)	2001-08-15	Kinasoliiniderivaadid, nende valmistamismeetod ja kasutamine
FI941137L (fi)	1994-09-12	2-debentsoyyli-2-asyylitaksolijohdannaisia ja menetelmiä niiden valmistamiseksi
FI964028L (fi)	1996-10-08	Uusi farmaseuttinen formulaatio ja menetelmä
EE03231B1 (et)	1999-10-15	Tetratsüklilised derivaadid, nende valmistamismeetod ja kasutamine
EE9700145A (et)	1998-02-16	Tsükloalkaanpüridiinid, nende valmistamismeetod, kasutamine ravimite tootmiseks ja nimetatud ühendeid sisaldavad ravimid
FI940585L (fi)	1994-08-11	Pinnoittamattomat tabletit ja menetelmä niiden valmistamiseksi
HU9204034D0 (en)	1993-03-29	Dialkoxi-pyridinyl-benzimidazole derivatives, method for producing them and their pharmaceutical application
FI955235L (fi)	1996-05-03	Oksatsolidiinionijohdannaiset, niiden valmistus ja käyttö
EE9600172A (et)	1997-06-16	Puriin-6-ooni derivaadid, nende valmistamismeetod, kasutamine ravimite valmistamiseks ja ravimid
FI944279L (fi)	1994-09-15	Suolatuote ja menetelmä sen valmistamiseksi
FI935465L (fi)	1994-06-08	Termoplastinen koostumus, menetelmä sen valmistamiseksi ja sen käyttö
FI953898A0 (fi)	1995-08-18	Glysiiniamidijohdannaisia, menetelmiä niiden valmistamiseksi ja niitä sisältäviä lääkeaineita
EE9800302A (et)	1999-02-15	Arüülglütsiinamiidi derivaadid, nende valmistamismeetod ja kasutamine ning farmatseutiline preparaat
FI956080L (fi)	1996-01-17	Kuidutettu selluloosatuote ja menetelmä sen valmistamiseksi
EE9800109A (et)	1998-10-15	5-O-desosaminüül-6-O-metüülerütronoliid A uued derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete produktide valmistamiseks
FI950135L (fi)	1995-01-11	Viljatuote, sen käyttötapa ja valmistusmenetelmä
FI963881L (fi)	1996-09-27	5H-indeno/1,2-b/pyratsin-2,3-dionijohdannaiset, niiden valmistus ja niitä sisältävät lääkkeet
FI942499L (fi)	1994-07-27	Indolijohdannainen, menetelmä sen valmistamiseksi ja sen lääkekäyttö
EE9900112A (et)	1999-10-15	2-tsüanoiminoimidasooli derivaadid, nende valmistamismeetod, kasutamine ja farmatseutilised kompositsioonid
FI944713L (fi)	1994-12-02	4-difenyylimetyylipiperidiinijohdannaisia ja menetelmä niiden valmistamiseksi
EE9800145A (et)	1998-10-15	Fenüülamidiini derivaadid, meetodid nende valmistamiseks ja nende kasutamine arstimitena
FI951631L (fi)	1995-04-05	Substituoituja kynureniinejä, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä
EE9800423A (et)	1999-06-15	Suhkruga kaetud tooted ja meetod nende valmistamiseks
FI943642L (fi)	1994-08-05	Sulfatoidut polysakkaridit, menetelmä niiden valmistamiseksi, farmaseuttinen valmistus ja käyttö

Legal Events

Date	Code	Title	Description
2003-02-17	KB4A	Valid patent at the end of a year	Effective date: 20021231
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2004-12-15	GB1A	Change in the ownership or in the address of the owner
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2008-02-15	KB4A	Valid patent at the end of a year	Effective date: 20071231
2009-02-16	KB4A	Valid patent at the end of a year	Effective date: 20081231
2010-02-15	KB4A	Valid patent at the end of a year	Effective date: 20091231
2011-02-15	KB4A	Valid patent at the end of a year	Effective date: 20101231