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FI944713L - 4-difenyylimetyylipiperidiinijohdannaisia ja menetelmä niiden valmistamiseksi - Google Patents

4-difenyylimetyylipiperidiinijohdannaisia ja menetelmä niiden valmistamiseksi Download PDF

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Publication number
FI944713L
FI944713L FI944713A FI944713A FI944713L FI 944713 L FI944713 L FI 944713L FI 944713 A FI944713 A FI 944713A FI 944713 A FI944713 A FI 944713A FI 944713 L FI944713 L FI 944713L
Authority
FI
Finland
Prior art keywords
preparation
diphenylmethylpiperidine
derivatives
diphenylmethylpiperidine derivatives
Prior art date
Application number
FI944713A
Other languages
English (en)
Swedish (sv)
Other versions
FI944713A0 (fi
FI106454B (fi
Inventor
Michele Ann Kaminski
Chi-Hsin Richard King
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Publication of FI944713A0 publication Critical patent/FI944713A0/fi
Publication of FI944713L publication Critical patent/FI944713L/fi
Application granted granted Critical
Publication of FI106454B publication Critical patent/FI106454B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI944713A 1992-04-10 1994-10-07 Menetelmä 4-[4-[4-(hydroksidifenyylimetyyli)-1-piperidinyyli]-1-hydroksibutyyli]- ja 4-[4-[4-(hydroksidifenyylimetyyli)-1-piperidinyyli]-1-oksobutyyli]johdannaisten valmistamiseksi FI106454B (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US86726192A 1992-04-10 1992-04-10
US86726192 1992-04-10
US1725193A 1993-02-25 1993-02-25
US1725193 1993-02-25
US9302103 1993-03-10
PCT/US1993/002103 WO1993021156A1 (en) 1992-04-10 1993-03-10 4-diphenylmethyl piperidine derivatives and process for their preparation

Publications (3)

Publication Number Publication Date
FI944713A0 FI944713A0 (fi) 1994-10-07
FI944713L true FI944713L (fi) 1994-12-02
FI106454B FI106454B (fi) 2001-02-15

Family

ID=26689638

Family Applications (2)

Application Number Title Priority Date Filing Date
FI944713A FI106454B (fi) 1992-04-10 1994-10-07 Menetelmä 4-[4-[4-(hydroksidifenyylimetyyli)-1-piperidinyyli]-1-hydroksibutyyli]- ja 4-[4-[4-(hydroksidifenyylimetyyli)-1-piperidinyyli]-1-oksobutyyli]johdannaisten valmistamiseksi
FI20002460A FI20002460L (fi) 1992-04-10 2000-11-09 4-difenyylimetyylipiperidiinijohdannaisia

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI20002460A FI20002460L (fi) 1992-04-10 2000-11-09 4-difenyylimetyylipiperidiinijohdannaisia

Country Status (19)

Country Link
EP (1) EP0635004B1 (fi)
JP (3) JP3686950B2 (fi)
KR (1) KR100257805B1 (fi)
AR (1) AR253777A1 (fi)
AT (1) ATE220666T1 (fi)
AU (1) AU671822B2 (fi)
CA (1) CA2117892C (fi)
DE (1) DE69332117T2 (fi)
DK (1) DK0635004T3 (fi)
ES (1) ES2176201T3 (fi)
FI (2) FI106454B (fi)
HU (1) HU226561B1 (fi)
IL (1) IL105328A (fi)
MX (1) MX9302076A (fi)
NO (5) NO305076B1 (fi)
NZ (1) NZ251132A (fi)
PT (1) PT635004E (fi)
TW (1) TW362096B (fi)
WO (1) WO1993021156A1 (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL174373B1 (pl) * 1992-08-03 1998-07-31 Sepracor Inc Środek farmaceutyczny zawierający metabolit terfenadyny
JP3034047B2 (ja) * 1993-06-24 2000-04-17 オールバニー・モレキュラー・リサーチ・インコーポレイテッド ピペリジン誘導体及びそれらの製造法
US20020007068A1 (en) 1999-07-16 2002-01-17 D'ambra Thomas E. Piperidine derivatives and process for their production
US6147216A (en) * 1993-06-25 2000-11-14 Merrell Pharmaceuticals Inc. Intermediates useful for the preparation of antihistaminic piperidine derivatives
CA2362339C (en) 1993-06-25 2005-08-02 Merrell Pharmaceuticals Inc. Novel intermediates for the preparation of antihistaminic 4-diphenylmethyl/diphenylmethoxy piperidine derivatives
EP1178041A1 (en) 1994-05-18 2002-02-06 Aventis Pharmaceuticals Inc. Process for preparing anhydrous and hydrate forms of antihistaminic piperidine derivatives
MX9706449A (es) 1995-02-28 1997-11-29 Hoechst Marion Roussel Inc Composicion farmaceutica para compuestos de piperidinalcanol.
US6201124B1 (en) 1995-12-21 2001-03-13 Albany Molecular Research, Inc. Process for production of piperidine derivatives
US6153754A (en) 1995-12-21 2000-11-28 Albany Molecular Research, Inc. Process for production of piperidine derivatives
CN1246312C (zh) * 1998-07-02 2006-03-22 阿旺蒂斯制药公司 新的抗组胺哌啶衍生物及制备其的中间体
MXPA03009259A (es) * 2001-04-09 2004-06-03 Teva Pharma Polimorfos de clorhidrato de fexofenadina.
ITRM20010260A1 (it) 2001-05-17 2002-11-18 Dinamite Dipharma S P A In For Processo per la preparazione della fexofenadina o acido 4 1-idrossi-4-4- (idrossidifenilmetil)-1-piperidinil|-butil|-alfa,alfa-dimetilbenz
US6743941B2 (en) 2001-06-15 2004-06-01 Aventis Pharma Deutschland Gmbh Process for the production of piperidine derivatives
ES2239554T1 (es) 2002-06-10 2005-10-01 Teva Pharmaceutical Industries Ltd. Forma xvi polimorfica de hidrocloruro de fexofenadina.
GB0319935D0 (en) 2003-08-26 2003-09-24 Cipla Ltd Polymorphs
ITMI20061492A1 (it) * 2006-07-27 2008-01-28 Archimica Srl Processo per la preparazione di fexofenadina.
ITMI20070987A1 (it) 2007-05-16 2008-11-17 Dipharma Francis Srl Procedimento per la preparazione di composti chetonici
EP2289867A3 (en) 2009-08-19 2012-04-25 Jubilant Organosys Limited A process for producing 4-(4-halo-1-oxybutyl)-alpha,alpha-dimethylbenzene acetic acid or alkyl esters thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4254129A (en) * 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives
US4254130A (en) * 1979-04-10 1981-03-03 Richardson-Merrell Inc. Piperidine derivatives

Also Published As

Publication number Publication date
AR253777A1 (es) 2001-10-08
MX9302076A (es) 1994-03-31
NO943794L (no) 1994-12-09
HUT70517A (en) 1995-10-30
JP4266184B2 (ja) 2009-05-20
EP0635004B1 (en) 2002-07-17
FI944713A0 (fi) 1994-10-07
FI20002460L (fi) 2000-11-09
NO981432D0 (no) 1998-03-30
DE69332117D1 (de) 2002-08-22
JP3686950B2 (ja) 2005-08-24
KR100257805B1 (ko) 2000-07-01
NO305024B1 (no) 1999-03-22
DK0635004T3 (da) 2002-11-11
CA2117892A1 (en) 1993-10-28
NO943794D0 (no) 1994-10-07
NO305077B1 (no) 1999-03-29
HU9402913D0 (en) 1995-01-30
JP2005213268A (ja) 2005-08-11
NO981433D0 (no) 1998-03-30
NO305023B1 (no) 1999-03-22
NO981434L (no) 1994-12-09
NO981433L (no) 1994-12-09
NO981432L (no) 1994-12-09
FI106454B (fi) 2001-02-15
EP0635004A1 (en) 1995-01-25
NO305076B1 (no) 1999-03-29
NO981431L (no) 1994-12-09
NO981431D0 (no) 1998-03-30
PT635004E (pt) 2002-12-31
CA2117892C (en) 2001-12-18
AU671822B2 (en) 1996-09-12
HU226561B1 (en) 2009-04-28
ES2176201T3 (es) 2002-12-01
ATE220666T1 (de) 2002-08-15
TW362096B (en) 1999-06-21
JP2004285072A (ja) 2004-10-14
NO305025B1 (no) 1999-03-22
WO1993021156A1 (en) 1993-10-28
NZ251132A (en) 1996-12-20
IL105328A (en) 2007-03-08
IL105328A0 (en) 1993-08-18
JPH08502022A (ja) 1996-03-05
NO981434D0 (no) 1998-03-30
KR950700881A (ko) 1995-02-20
AU3797393A (en) 1993-11-18
DE69332117T2 (de) 2003-01-30

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Owner name: AVENTIS INC.

Free format text: AVENTIS INC.

PC Transfer of assignment of patent

Owner name: AVENTISUB II INC.

Free format text: AVENTISUB II INC.

MA Patent expired