ECSP088105A - Derivados de n-(arilalquil)-1h-pirrolopiridin-2-carboxamidas, su preparación y su aplicación en terapéutica - Google Patents
Derivados de n-(arilalquil)-1h-pirrolopiridin-2-carboxamidas, su preparación y su aplicación en terapéuticaInfo
- Publication number
- ECSP088105A ECSP088105A EC2008008105A ECSP088105A ECSP088105A EC SP088105 A ECSP088105 A EC SP088105A EC 2008008105 A EC2008008105 A EC 2008008105A EC SP088105 A ECSP088105 A EC SP088105A EC SP088105 A ECSP088105 A EC SP088105A
- Authority
- EC
- Ecuador
- Prior art keywords
- group
- pyrrolo
- aryl
- alkylene
- alkyl
- Prior art date
Links
- 239000003814 drug Substances 0.000 title abstract 2
- XWIYUCRMWCHYJR-UHFFFAOYSA-N 1h-pyrrolo[3,2-b]pyridine Chemical group C1=CC=C2NC=CC2=N1 XWIYUCRMWCHYJR-UHFFFAOYSA-N 0.000 abstract 3
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- XLKDJOPOOHHZAN-UHFFFAOYSA-N 1h-pyrrolo[2,3-c]pyridine Chemical group C1=NC=C2NC=CC2=C1 XLKDJOPOOHHZAN-UHFFFAOYSA-N 0.000 abstract 1
- SRSKXJVMVSSSHB-UHFFFAOYSA-N 1h-pyrrolo[3,2-c]pyridine Chemical group N1=CC=C2NC=CC2=C1 SRSKXJVMVSSSHB-UHFFFAOYSA-N 0.000 abstract 1
- -1 C (O) NR1R2 Chemical group 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000005842 heteroatom Chemical group 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Virology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Communicable Diseases (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Obesity (AREA)
- Molecular Biology (AREA)
- Gynecology & Obstetrics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Emergency Medicine (AREA)
- Nutrition Science (AREA)
Abstract
La invención se refiere a los compuestos de fórmula general (I) : en la que n es igual a 0, 1 , 2 ó 3 ; el núcleo pirrolopiridina es un grupo pirrolo[3,2-b]piridina, un grupo pirrolo[3,2-c]piridina, un grupo pirrolo[2,3-c]piridina o un grupo pirrolo[2,3-b]piridina; estando el núcleo pirrolopiridina opcionalmente sustituido en posición carbonada 4, 5, 6 y/o 7 con uno o varios sustituyentes X, idénticos o difernetes uno del otro ; Z1, Z2, Z3, Z4 y Z5 representan, independientemente uno del otro, un átomo de hidrógeno o de halógeno o un grupo alquilo-C1-C6, cicloalquilo-C3-C7, cicloalquilo-C3-C7-alquileno-C1-C3, fluoroalquilo-C1-C6, alcoxilo-C1-C6, fluoroalcoxilo-C1-C6, ciano, C(O)NR1R2, nitro, NR1R2, tioalquilo-C1-C6, -S(O)-alquilo-C1-C6, - S(O)2-alquilo-C1-C6, SO2NR1R2, NR3COR4, NR3SO2R5 , arilo-alquileno-C1-C6 o arilo, estando el arilo y arilo-alquileno-C1-C6 opcionalmente sustituidos; W representa un grupo bicíclico fusionado de fórmula : unido al átomo de nitrógeno por las posiciones 1, 2, 3 ó 4 ; A representa un heterociclo opcionalmente sustituido de 5 a 7 eslabones que comprende de uno a tres heteroátomos elegidos entre O, S o N ; en el estado de base o de sal de adición a un ácido, así como en el estado de hidrato o de solvato. Procedimiento de preparación y aplicación en terapéutica.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0507804A FR2888848B1 (fr) | 2005-07-22 | 2005-07-22 | Derives de n-(arylalkyl)-1h-pyrrrolopyridine-2-carboxamides, leur preparation et leur application en therapeutique |
| PCT/FR2006/001767 WO2007010138A2 (fr) | 2005-07-22 | 2006-07-19 | Derives de ν-(arylalkyl)-1h-pyrrolopyridine-2-carboxamides, leur preparation et leur application en therapeutique |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP088105A true ECSP088105A (es) | 2008-02-20 |
Family
ID=36039505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2008008105A ECSP088105A (es) | 2005-07-22 | 2008-01-14 | Derivados de n-(arilalquil)-1h-pirrolopiridin-2-carboxamidas, su preparación y su aplicación en terapéutica |
Country Status (35)
| Country | Link |
|---|---|
| US (2) | US7763636B2 (es) |
| EP (1) | EP1912644B1 (es) |
| JP (1) | JP4938012B2 (es) |
| KR (1) | KR101257969B1 (es) |
| CN (1) | CN101247808B (es) |
| AR (1) | AR057668A1 (es) |
| AT (1) | ATE451923T1 (es) |
| AU (1) | AU2006271518B2 (es) |
| BR (1) | BRPI0614066A2 (es) |
| CA (1) | CA2615676C (es) |
| CR (1) | CR9643A (es) |
| CY (1) | CY1109891T1 (es) |
| DE (1) | DE602006011170D1 (es) |
| DK (1) | DK1912644T3 (es) |
| EA (1) | EA013747B1 (es) |
| EC (1) | ECSP088105A (es) |
| ES (1) | ES2338363T3 (es) |
| FR (1) | FR2888848B1 (es) |
| HR (1) | HRP20100150T1 (es) |
| IL (1) | IL188520A (es) |
| MA (1) | MA29617B1 (es) |
| MX (1) | MX2008001018A (es) |
| MY (1) | MY145062A (es) |
| NI (1) | NI200800021A (es) |
| NO (1) | NO20080394L (es) |
| NZ (1) | NZ564870A (es) |
| PL (1) | PL1912644T3 (es) |
| PT (1) | PT1912644E (es) |
| RS (1) | RS51233B (es) |
| SI (1) | SI1912644T1 (es) |
| TN (1) | TNSN07485A1 (es) |
| TW (1) | TWI386407B (es) |
| UA (1) | UA93881C2 (es) |
| WO (1) | WO2007010138A2 (es) |
| ZA (1) | ZA200800439B (es) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2888847B1 (fr) | 2005-07-22 | 2007-08-31 | Sanofi Aventis Sa | Derives de n-(heteriaryl)-1-heteorarylalkyl-1h-indole-2- carboxamides, leur preparation et application en therapeutique |
| FR2910473B1 (fr) | 2006-12-26 | 2009-02-13 | Sanofi Aventis Sa | Derives de n-(amino-heteroaryl)-1h-pyrrolopyridine-2- carboxamides, leur preparation et leur application en therapeutique. |
| FR2911605B1 (fr) * | 2007-01-19 | 2009-04-17 | Sanofi Aventis Sa | Derives de pyrrolopyridine-2-carbowamides, leur preparation et leur application en therapeutique |
| JP5580735B2 (ja) * | 2007-06-12 | 2014-08-27 | ジェネンテック， インコーポレイテッド | Ｎ−置換アザインドール類及び使用方法 |
| FR2919610B1 (fr) * | 2007-08-02 | 2009-10-16 | Sanofi Aventis Sa | Derives de n-heteroaryl-carboxamides tricycliques,leur preparation et leur application en therapeutique |
| FR2926556B1 (fr) * | 2008-01-22 | 2010-02-19 | Sanofi Aventis | Derives de carboxamides n-azabicycliques, leur preparation et leur application en therapeutique |
| FR2926555B1 (fr) * | 2008-01-22 | 2010-02-19 | Sanofi Aventis | Derives bicycliques de carboxamides azabicycliques, leur preparation et leur application en therapeutique |
| FR2926554B1 (fr) | 2008-01-22 | 2010-03-12 | Sanofi Aventis | Derives de carboxamides azabicycliques, leur preparation et leur application en therapeutique |
| GB0915892D0 (en) * | 2009-09-10 | 2009-10-14 | Smithkline Beecham Corp | Compounds |
| GB201913756D0 (en) * | 2019-09-24 | 2019-11-06 | Chromatwist Ltd | Contrast agent |
| US20230137893A1 (en) * | 2020-02-05 | 2023-05-04 | The Rockefeller University | PYRROLO[2,3-b]PYRIDINE-3-CARBOXAMIDE COMPOSITIONS AND METHODS FOR AMELIORATING HEARING LOSS |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08295667A (ja) * | 1995-04-27 | 1996-11-12 | Takeda Chem Ind Ltd | 複素環化合物、その製造法および剤 |
| JP4241970B2 (ja) * | 1998-10-30 | 2009-03-18 | 中外製薬株式会社 | アミド結合を有するインドール誘導体、及びモノ又はジアザインドール誘導体 |
| US6436965B1 (en) * | 2000-03-02 | 2002-08-20 | Merck Frosst Canada & Co. | PDE IV inhibiting amides, compositions and methods of treatment |
| TW200403223A (en) * | 2002-02-15 | 2004-03-01 | Glaxo Group Ltd | Novel compounds |
| JP2004091480A (ja) * | 2002-07-11 | 2004-03-25 | Takeda Chem Ind Ltd | ピロロピリジン誘導体およびその用途 |
| AU2003281044A1 (en) * | 2002-07-11 | 2004-02-02 | Takeda Pharmaceutical Company Limited | Pyrrolopyridine derivative and use thereof |
| JP4909068B2 (ja) * | 2003-02-14 | 2012-04-04 | グラクソ グループ リミテッド | カルボキサミド誘導体 |
| US7544803B2 (en) * | 2004-01-23 | 2009-06-09 | Amgen Inc. | Vanilloid receptor ligands and their use in treatments |
| FR2897061B1 (fr) * | 2006-02-03 | 2010-09-03 | Sanofi Aventis | Derives de n-heteroaryl-carboxamides tricycliques contenant un motif benzimidazole, leur preparation et leur application en therapeutique. |
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2005
- 2005-07-22 FR FR0507804A patent/FR2888848B1/fr not_active Expired - Fee Related
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2006
- 2006-07-19 JP JP2008522019A patent/JP4938012B2/ja not_active Expired - Fee Related
- 2006-07-19 PT PT06778888T patent/PT1912644E/pt unknown
- 2006-07-19 EA EA200800402A patent/EA013747B1/ru not_active IP Right Cessation
- 2006-07-19 ZA ZA200800439A patent/ZA200800439B/xx unknown
- 2006-07-19 BR BRPI0614066-1A patent/BRPI0614066A2/pt active Search and Examination
- 2006-07-19 MX MX2008001018A patent/MX2008001018A/es active IP Right Grant
- 2006-07-19 RS RSP-2010/0116A patent/RS51233B/sr unknown
- 2006-07-19 AT AT06778888T patent/ATE451923T1/de active
- 2006-07-19 AU AU2006271518A patent/AU2006271518B2/en not_active Ceased
- 2006-07-19 WO PCT/FR2006/001767 patent/WO2007010138A2/fr active Application Filing
- 2006-07-19 ES ES06778888T patent/ES2338363T3/es active Active
- 2006-07-19 NZ NZ564870A patent/NZ564870A/en not_active IP Right Cessation
- 2006-07-19 DK DK06778888.5T patent/DK1912644T3/da active
- 2006-07-19 SI SI200630591T patent/SI1912644T1/sl unknown
- 2006-07-19 KR KR1020087001597A patent/KR101257969B1/ko not_active IP Right Cessation
- 2006-07-19 PL PL06778888T patent/PL1912644T3/pl unknown
- 2006-07-19 EP EP06778888A patent/EP1912644B1/fr active Active
- 2006-07-19 CA CA2615676A patent/CA2615676C/fr not_active Expired - Fee Related
- 2006-07-19 CN CN200680030739.0A patent/CN101247808B/zh not_active Expired - Fee Related
- 2006-07-19 UA UAA200802257A patent/UA93881C2/ru unknown
- 2006-07-19 DE DE602006011170T patent/DE602006011170D1/de active Active
- 2006-07-20 AR ARP060103112A patent/AR057668A1/es unknown
- 2006-07-20 MY MYPI20063489A patent/MY145062A/en unknown
- 2006-07-21 TW TW095126724A patent/TWI386407B/zh not_active IP Right Cessation
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2007
- 2007-12-26 TN TNP2007000485A patent/TNSN07485A1/fr unknown
- 2007-12-31 IL IL188520A patent/IL188520A/en not_active IP Right Cessation
-
2008
- 2008-01-07 MA MA30554A patent/MA29617B1/fr unknown
- 2008-01-08 US US11/970,886 patent/US7763636B2/en not_active Expired - Fee Related
- 2008-01-08 CR CR9643A patent/CR9643A/es unknown
- 2008-01-14 EC EC2008008105A patent/ECSP088105A/es unknown
- 2008-01-18 NI NI200800021A patent/NI200800021A/es unknown
- 2008-01-21 NO NO20080394A patent/NO20080394L/no not_active Application Discontinuation
-
2010
- 2010-03-12 CY CY20101100239T patent/CY1109891T1/el unknown
- 2010-03-16 HR HR20100150T patent/HRP20100150T1/hr unknown
- 2010-06-15 US US12/815,593 patent/US20100249183A1/en not_active Abandoned
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