DK1840121T3 - Glycinderivat og anvendelse heraf - Google Patents
Glycinderivat og anvendelse herafInfo
- Publication number
- DK1840121T3 DK1840121T3 DK05820176.5T DK05820176T DK1840121T3 DK 1840121 T3 DK1840121 T3 DK 1840121T3 DK 05820176 T DK05820176 T DK 05820176T DK 1840121 T3 DK1840121 T3 DK 1840121T3
- Authority
- DK
- Denmark
- Prior art keywords
- glycine derivative
- glycine
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
- C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/04—Seven-membered rings not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004372880 | 2004-12-24 | ||
| PCT/JP2005/023577 WO2006068213A1 (ja) | 2004-12-24 | 2005-12-22 | グリシン誘導体及びその用途 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1840121T3 true DK1840121T3 (da) | 2012-11-26 |
Family
ID=36601810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK05820176.5T DK1840121T3 (da) | 2004-12-24 | 2005-12-22 | Glycinderivat og anvendelse heraf |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US7566724B2 (da) |
| EP (1) | EP1840121B1 (da) |
| JP (1) | JP4862655B2 (da) |
| KR (1) | KR101250889B1 (da) |
| CN (1) | CN101128436B (da) |
| AU (1) | AU2005320089B2 (da) |
| CA (1) | CA2592170C (da) |
| DK (1) | DK1840121T3 (da) |
| ES (1) | ES2390281T3 (da) |
| PL (1) | PL1840121T3 (da) |
| PT (1) | PT1840121E (da) |
| WO (1) | WO2006068213A1 (da) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2655286C (en) | 2006-06-14 | 2014-02-25 | Toray Industries, Inc. | Therapeutic or prophylactic agent for allergic dermatitis |
| KR101423347B1 (ko) * | 2006-06-19 | 2014-07-24 | 도레이 카부시키가이샤 | 다발성 경화증의 치료 또는 예방제 |
| US7893046B2 (en) * | 2006-06-20 | 2011-02-22 | Toray Industries, Inc. | Therapeutic or prophylactic agent for leukemia |
| CA2837453C (en) * | 2011-06-30 | 2017-04-11 | Toray Industries, Inc. | Crystals of glycine derivative and pharmaceutical use thereof |
| JP5724851B2 (ja) * | 2011-11-30 | 2015-05-27 | 東レ株式会社 | Ｎ−（ヨードフェニル）ピリミジニルアミン誘導体の製造方法 |
| JPWO2014051056A1 (ja) * | 2012-09-28 | 2016-08-22 | 東レ株式会社 | グリシン誘導体の結晶及びその医薬用途 |
| KR102659859B1 (ko) | 2018-10-30 | 2024-04-25 | 길리애드 사이언시즈, 인코포레이티드 | 알파4β7 인테그린의 억제를 위한 화합물 |
| ES2987796T3 (es) | 2018-10-30 | 2024-11-18 | Gilead Sciences Inc | Derivados de N-benzoil-fenilalanina como inhibidores de la integrina alfa4beta7 para el tratamiento de enfermedades inflamatorias |
| AU2019373244B2 (en) | 2018-10-30 | 2022-05-26 | Gilead Sciences, Inc. | Imidazopyridine derivatives as alpha4beta7 integrin inhibitors |
| EP3873884B1 (en) | 2018-10-30 | 2024-12-04 | Gilead Sciences, Inc. | 3-(quinolin-8-yl)-1,4-dihydropyrido[3,4-d]pyrimidin-2,4-dione derivatives as alpha4beta7 integrin inhibitors for the treatment of inflammatory diseases |
| US11578069B2 (en) | 2019-08-14 | 2023-02-14 | Gilead Sciences, Inc. | Compounds for inhibition of α4 β7 integrin |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995032710A1 (en) | 1994-05-27 | 1995-12-07 | Merck & Co., Inc. | Compounds for inhibiting osteoclast-mediated bone resorption |
| AU1411499A (en) | 1997-11-20 | 1999-06-15 | Merck & Co., Inc. | Para-aminomethylaryl carboxamide derivatives |
| US6191171B1 (en) * | 1997-11-20 | 2001-02-20 | Merck & Co., Inc. | Para-aminomethylaryl carboxamide derivatives |
| CA2382757A1 (en) * | 1999-07-26 | 2001-02-01 | Toray Industries, Inc. | Carboxylic acid derivatives and adhesion molecule inhibitors which contain the same as effective ingredients |
| EP1270547A4 (en) * | 2000-03-23 | 2005-07-13 | Ajinomoto Kk | NEW PHENYL ALANIDE DERIVATIVES |
| EP1454898A4 (en) * | 2001-12-13 | 2006-12-13 | Ajinomoto Kk | NEW PHENYL ALANIDE DERIVATIVES |
| JP2003277340A (ja) * | 2002-03-22 | 2003-10-02 | Toray Ind Inc | 接着分子阻害剤及び新規アミノ酸誘導体 |
-
2005
- 2005-12-22 CN CN2005800486199A patent/CN101128436B/zh not_active Expired - Fee Related
- 2005-12-22 PL PL05820176T patent/PL1840121T3/pl unknown
- 2005-12-22 EP EP05820176A patent/EP1840121B1/en not_active Not-in-force
- 2005-12-22 US US11/793,841 patent/US7566724B2/en not_active Expired - Fee Related
- 2005-12-22 KR KR1020077015372A patent/KR101250889B1/ko not_active IP Right Cessation
- 2005-12-22 CA CA2592170A patent/CA2592170C/en not_active Expired - Fee Related
- 2005-12-22 PT PT05820176T patent/PT1840121E/pt unknown
- 2005-12-22 JP JP2006549053A patent/JP4862655B2/ja not_active Expired - Fee Related
- 2005-12-22 WO PCT/JP2005/023577 patent/WO2006068213A1/ja active Application Filing
- 2005-12-22 AU AU2005320089A patent/AU2005320089B2/en not_active Ceased
- 2005-12-22 ES ES05820176T patent/ES2390281T3/es active Active
- 2005-12-22 DK DK05820176.5T patent/DK1840121T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| KR101250889B1 (ko) | 2013-04-04 |
| PT1840121E (pt) | 2012-10-29 |
| CA2592170C (en) | 2013-10-15 |
| CN101128436A (zh) | 2008-02-20 |
| JPWO2006068213A1 (ja) | 2008-06-12 |
| PL1840121T3 (pl) | 2013-01-31 |
| AU2005320089B2 (en) | 2011-04-07 |
| EP1840121B1 (en) | 2012-08-29 |
| US7566724B2 (en) | 2009-07-28 |
| CA2592170A1 (en) | 2006-06-29 |
| KR20070095312A (ko) | 2007-09-28 |
| US20080085910A1 (en) | 2008-04-10 |
| EP1840121A1 (en) | 2007-10-03 |
| AU2005320089A1 (en) | 2006-06-29 |
| EP1840121A4 (en) | 2011-05-11 |
| ES2390281T3 (es) | 2012-11-08 |
| CN101128436B (zh) | 2010-12-22 |
| JP4862655B2 (ja) | 2012-01-25 |
| WO2006068213A1 (ja) | 2006-06-29 |
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