DK1934179T3 - Fremgangsmåder og mellemprodukter - Google Patents

Fremgangsmåder og mellemprodukter

Info

Publication number: DK1934179T3
Authority: DK; Denmark
Prior art keywords: intermediates; methods
Prior art date: 2005-08-19

Application number

DK06813568.0T

Other languages

English (en)

Inventor

Gerald J Tanoury

Minzhang Chen

John E Cochran

Original Assignee

Vertex Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-08-19

Filing date

2006-08-18

Publication date

2010-08-09

2006-08-18 Application filed by Vertex Pharma filed Critical Vertex Pharma

2010-08-09 Application granted granted Critical

2010-08-09 Publication of DK1934179T3 publication Critical patent/DK1934179T3/da

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Virology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Epidemiology (AREA)
Emergency Medicine (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Indole Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Enzymes And Modification Thereof (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK06813568.0T 2005-08-19 2006-08-18 Fremgangsmåder og mellemprodukter DK1934179T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US70996405P	2005-08-19	2005-08-19
US81004206P	2006-06-01	2006-06-01
PCT/US2006/032481 WO2007022459A2 (en)	2005-08-19	2006-08-18	Processes and intermediates

Publications (1)

Publication Number	Publication Date
DK1934179T3 true DK1934179T3 (da)	2010-08-09

Family

ID=37708299

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK06813568.0T DK1934179T3 (da)	2005-08-19	2006-08-18	Fremgangsmåder og mellemprodukter
DK10155058.0T DK2194043T3 (da)	2005-08-19	2006-08-18	Fremgangsmåder

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DK10155058.0T DK2194043T3 (da)	2005-08-19	2006-08-18	Fremgangsmåder

Country Status (25)

Country	Link
US (3)	US7776887B2 (da)
EP (4)	EP2364970A1 (da)
JP (1)	JP5203203B2 (da)
KR (4)	KR20130110236A (da)
CN (2)	CN101291909B (da)
AR (1)	AR058025A1 (da)
AT (1)	ATE463480T1 (da)
AU (1)	AU2006279357B2 (da)
BR (1)	BRPI0615029A2 (da)
CA (1)	CA2619659A1 (da)
CY (2)	CY1110214T1 (da)
DE (1)	DE602006013492D1 (da)
DK (2)	DK1934179T3 (da)
ES (2)	ES2449268T3 (da)
HK (2)	HK1122801A1 (da)
IL (2)	IL189585A (da)
NZ (3)	NZ593214A (da)
PL (3)	PL2194043T3 (da)
PT (2)	PT2194043E (da)
RU (2)	RU2446171C2 (da)
SG (1)	SG2014013338A (da)
SI (2)	SI2194043T1 (da)
TW (2)	TWI391376B (da)
WO (1)	WO2007022459A2 (da)
ZA (1)	ZA200801791B (da)

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2006
- 2006-08-18 KR KR1020137024964A patent/KR20130110236A/ko not_active Application Discontinuation
- 2006-08-18 ES ES10155058.0T patent/ES2449268T3/es active Active
- 2006-08-18 PT PT101550580T patent/PT2194043E/pt unknown
- 2006-08-18 JP JP2008527189A patent/JP5203203B2/ja not_active Expired - Fee Related
- 2006-08-18 CN CN2006800384541A patent/CN101291909B/zh not_active Expired - Fee Related
- 2006-08-18 EP EP11150041A patent/EP2364970A1/en not_active Withdrawn
- 2006-08-18 ES ES06813568T patent/ES2344156T3/es active Active
- 2006-08-18 AT AT06813568T patent/ATE463480T1/de active
- 2006-08-18 PL PL10155058T patent/PL2194043T3/pl unknown
- 2006-08-18 SI SI200631745T patent/SI2194043T1/sl unknown
- 2006-08-18 CN CN2011102403592A patent/CN102382170A/zh active Pending
- 2006-08-18 EP EP11150039A patent/EP2357170A1/en not_active Withdrawn
- 2006-08-18 EP EP06813568A patent/EP1934179B1/en not_active Not-in-force
- 2006-08-18 AU AU2006279357A patent/AU2006279357B2/en not_active Ceased
- 2006-08-18 DK DK06813568.0T patent/DK1934179T3/da active
- 2006-08-18 DK DK10155058.0T patent/DK2194043T3/da active
- 2006-08-18 AR ARP060103610A patent/AR058025A1/es unknown
- 2006-08-18 EP EP10155058.0A patent/EP2194043B1/en not_active Not-in-force
- 2006-08-18 KR KR1020147013418A patent/KR20140069370A/ko not_active Application Discontinuation
- 2006-08-18 TW TW095130511A patent/TWI391376B/zh not_active IP Right Cessation
- 2006-08-18 PL PL06813568T patent/PL1934179T4/pl unknown
- 2006-08-18 SI SI200630710T patent/SI1934179T1/sl unknown
- 2006-08-18 RU RU2008110479/04A patent/RU2446171C2/ru not_active IP Right Cessation
- 2006-08-18 TW TW101126397A patent/TW201245149A/zh unknown
- 2006-08-18 NZ NZ593214A patent/NZ593214A/xx not_active IP Right Cessation
- 2006-08-18 SG SG2014013338A patent/SG2014013338A/en unknown
- 2006-08-18 KR KR1020137005426A patent/KR20130038947A/ko not_active Application Discontinuation
- 2006-08-18 PL PL385229A patent/PL385229A1/pl not_active Application Discontinuation
- 2006-08-18 NZ NZ604087A patent/NZ604087A/en not_active IP Right Cessation
- 2006-08-18 US US11/506,550 patent/US7776887B2/en not_active Expired - Fee Related
- 2006-08-18 CA CA002619659A patent/CA2619659A1/en not_active Abandoned
- 2006-08-18 BR BRPI0615029-2A patent/BRPI0615029A2/pt not_active IP Right Cessation
- 2006-08-18 PT PT06813568T patent/PT1934179E/pt unknown
- 2006-08-18 DE DE602006013492T patent/DE602006013492D1/de active Active
- 2006-08-18 NZ NZ566049A patent/NZ566049A/en not_active IP Right Cessation
- 2006-08-18 WO PCT/US2006/032481 patent/WO2007022459A2/en active Application Filing
2008
- 2008-02-18 IL IL189585A patent/IL189585A/en not_active IP Right Cessation
- 2008-02-25 ZA ZA200801791A patent/ZA200801791B/xx unknown
- 2008-03-18 KR KR1020087006558A patent/KR101474405B1/ko not_active IP Right Cessation
- 2008-12-23 HK HK08113896.0A patent/HK1122801A1/xx not_active IP Right Cessation
2010
- 2010-03-15 US US12/661,319 patent/US8637457B2/en not_active Expired - Fee Related
- 2010-07-05 CY CY20101100613T patent/CY1110214T1/el unknown
- 2010-12-09 HK HK10111510.6A patent/HK1145022A1/xx not_active IP Right Cessation
2011
- 2011-11-29 RU RU2011148615/04A patent/RU2011148615A/ru not_active Application Discontinuation
2013
- 2013-10-07 IL IL228770A patent/IL228770A0/en unknown
- 2013-12-17 US US14/109,631 patent/US20140107318A1/en not_active Abandoned
2014
- 2014-02-25 CY CY20141100149T patent/CY1114916T1/el unknown

Also Published As

Publication number	Publication date
CN101291909B (zh)	2012-09-05
SG2014013338A (en)	2014-06-27
EP2194043A3 (en)	2010-11-24
HK1145022A1 (en)	2011-03-25
TW201245149A (en)	2012-11-16
KR101474405B1 (ko)	2014-12-23
IL228770A0 (en)	2013-12-31
WO2007022459A3 (en)	2008-02-28
CN102382170A (zh)	2012-03-21
AR058025A1 (es)	2008-01-23
ES2449268T3 (es)	2014-03-19
RU2008110479A (ru)	2009-09-27
JP2009504780A (ja)	2009-02-05
EP1934179A2 (en)	2008-06-25
CN101291909A (zh)	2008-10-22
EP2194043A2 (en)	2010-06-09
NZ604087A (en)	2014-07-25
KR20140069370A (ko)	2014-06-09
US8637457B2 (en)	2014-01-28
NZ566049A (en)	2011-07-29
US7776887B2 (en)	2010-08-17
IL189585A0 (en)	2008-08-07
NZ593214A (en)	2013-02-22
PL2194043T3 (pl)	2014-07-31
PL385229A1 (pl)	2008-09-29
PL1934179T4 (pl)	2014-03-31
KR20130110236A (ko)	2013-10-08
KR20130038947A (ko)	2013-04-18
DK2194043T3 (da)	2014-01-20
TW200800889A (en)	2008-01-01
CY1114916T1 (el)	2016-12-14
DE602006013492D1 (de)	2010-05-20
BRPI0615029A2 (pt)	2009-06-16
JP5203203B2 (ja)	2013-06-05
CA2619659A1 (en)	2007-02-22
RU2446171C2 (ru)	2012-03-27
AU2006279357A1 (en)	2007-02-22
ATE463480T1 (de)	2010-04-15
EP2194043B1 (en)	2013-12-25
PL1934179T3 (pl)	2010-09-30
CY1110214T1 (el)	2015-01-14
TWI391376B (zh)	2013-04-01
IL189585A (en)	2013-10-31
US20070087973A1 (en)	2007-04-19
HK1122801A1 (en)	2009-05-29
KR20080047396A (ko)	2008-05-28
ZA200801791B (en)	2008-12-31
AU2006279357B2 (en)	2012-05-31
US20140107318A1 (en)	2014-04-17
EP2364970A1 (en)	2011-09-14
EP1934179B1 (en)	2010-04-07
WO2007022459A2 (en)	2007-02-22
EP2357170A1 (en)	2011-08-17
PT1934179E (pt)	2010-07-12
SI1934179T1 (sl)	2010-08-31
PT2194043E (pt)	2014-03-04
ES2344156T3 (es)	2010-08-19
US20100174077A1 (en)	2010-07-08
SI2194043T1 (sl)	2014-04-30
RU2011148615A (ru)	2013-06-10

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ATE520680T1 (de)	2011-09-15	Hiv-hemmende 5-heterocyclylpyrimidine
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DK1955066T3 (da)	2014-05-05	Membran-assay-fremgangsmåde
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SE0400530L (sv)	2005-09-05	Förfarande
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DE112005000794T5 (de)	2007-05-16	Urethanspritzpistolenanordnung
ATE389633T1 (de)	2008-04-15	Omega-phenyloctanamide
AT500249A3 (de)	2006-03-15	Scheibenegge