[go: up one dir, main page]

DK1829874T3 - Tricyklisk forbindelse og anvendelse deraf - Google Patents

Tricyklisk forbindelse og anvendelse deraf

Info

Publication number
DK1829874T3
DK1829874T3 DK05820106T DK05820106T DK1829874T3 DK 1829874 T3 DK1829874 T3 DK 1829874T3 DK 05820106 T DK05820106 T DK 05820106T DK 05820106 T DK05820106 T DK 05820106T DK 1829874 T3 DK1829874 T3 DK 1829874T3
Authority
DK
Denmark
Prior art keywords
tricyclic compound
tricyclic
compound
Prior art date
Application number
DK05820106T
Other languages
English (en)
Inventor
Junichiro Manako
Yoshifumi Kagamiishi
Masashi Kato
Kazuyuki Ohmoto
Original Assignee
Ono Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co filed Critical Ono Pharmaceutical Co
Application granted granted Critical
Publication of DK1829874T3 publication Critical patent/DK1829874T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4375—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having nitrogen as a ring heteroatom, e.g. quinolizines, naphthyridines, berberine, vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK05820106T 2004-12-22 2005-12-21 Tricyklisk forbindelse og anvendelse deraf DK1829874T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2004371033 2004-12-22
JP2005261914 2005-09-09
PCT/JP2005/023450 WO2006068164A1 (ja) 2004-12-22 2005-12-21 三環式化合物およびその用途

Publications (1)

Publication Number Publication Date
DK1829874T3 true DK1829874T3 (da) 2014-05-12

Family

ID=36601763

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05820106T DK1829874T3 (da) 2004-12-22 2005-12-21 Tricyklisk forbindelse og anvendelse deraf

Country Status (8)

Country Link
US (4) US7964726B2 (da)
EP (1) EP1829874B1 (da)
JP (2) JP4997976B2 (da)
DK (1) DK1829874T3 (da)
ES (1) ES2459742T3 (da)
PL (1) PL1829874T3 (da)
PT (1) PT1829874E (da)
WO (1) WO2006068164A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4671123B2 (ja) * 2003-06-23 2011-04-13 小野薬品工業株式会社 新規三環性複素環化合物
PL1829874T3 (pl) * 2004-12-22 2014-07-31 Ono Pharmaceutical Co Tricykliczny związek i jego zastosowanie
DE102006033114A1 (de) * 2006-07-18 2008-01-24 Grünenthal GmbH Spirocyclische Azaindol-Derivate
JOP20180077A1 (ar) 2007-06-19 2019-01-30 Kythera Biopharmaceuticals Inc تركيبات وطرق لحمض صفراوي تخليقي
US20080318870A1 (en) 2007-06-19 2008-12-25 Kythera Biopharmaceuticals, Inc. Synthetic bile acid compositions and methods
US8242294B2 (en) 2007-06-19 2012-08-14 Kythera Biopharmaceuticals, Inc. Synthetic bile acid compositions and methods
TWI586666B (zh) * 2010-07-06 2017-06-11 Ono Pharmaceutical Co Tetrahydrocarboline Derivatives (2)
JP6690534B2 (ja) * 2014-06-12 2020-04-28 小野薬品工業株式会社 ストレス性疾患の予防および／または治療用医薬
US9907786B2 (en) 2014-10-21 2018-03-06 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing harmine and isovanillin components, and methods of use thereof
US10092550B2 (en) 2014-10-21 2018-10-09 Ions Pharmaceutical S.À R.L. Therapeutic compositions containing curcumin, harmine, and isovanillin components, and methods of use thereof
JP6731132B2 (ja) * 2015-01-09 2020-07-29 小野薬品工業株式会社 線維筋痛症の予防および／または治療剤
US10033334B1 (en) 2017-03-23 2018-07-24 Globalfoundries Inc. Peaking amplifier frequency tuning
US9853612B1 (en) 2017-03-23 2017-12-26 Globalfoundries Inc. Peaking amplifier frequency tuning
US12129265B2 (en) 2020-07-21 2024-10-29 Ankh Life Sciences Limited Therapeutic agents and uses thereof
JP2024502270A (ja) 2020-12-23 2024-01-18 リキュリウム アイピー ホールディングス リミテッド ライアビリティー カンパニー エストロゲン受容体調節薬

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1431702A (fr) 1964-11-23 1966-03-18 Sames Mach Electrostat Perfectionnements à l'élaboration des échantillons ou étalons utilisés en analyse radiochimique
SU788471A1 (ru) 1972-11-28 1981-12-30 Всесоюзный Научно-Исследовательский Химико-Фармацевтический Институт Им.С.Орджоникидзе Психотропное средство дл лечени депрессивных состо ний "инказан
US3959470A (en) * 1972-11-28 1976-05-25 Mikhail Davidovich Mashkovsky Psychotropic medicinal preparation
US4336260A (en) * 1977-12-08 1982-06-22 The Dow Chemical Company Method and compositions using 1-aryl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid for treating depression
EP0357122A3 (en) * 1988-08-29 1991-10-23 Duphar International Research B.V Use of beta-carbolines, their bio-isosteric benzofuran and benzothiophene analogues for the manufacture of a medicament having cytostatic properties
JPH03287586A (ja) * 1990-04-02 1991-12-18 Taisho Pharmaceut Co Ltd テトラヒドロ―β―カルボリン誘導体
GB9401090D0 (en) 1994-01-21 1994-03-16 Glaxo Lab Sa Chemical compounds
US5403851A (en) 1994-04-05 1995-04-04 Interneuron Pharmaceuticals, Inc. Substituted tryptamines, phenalkylamines and related compounds
FR2724384B1 (fr) * 1994-09-14 1999-04-16 Cemaf Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament
SK154498A3 (en) 1996-05-10 2000-01-18 Icos Corp Carboline derivatives, process for the preparation thereof, pharmaceutical compositions containing same and use of mentioned derivatives as drugs
EP1007067B1 (en) * 1996-10-21 2002-01-16 Morten Sloth Weidner Pharmaceutical compositions containing parthenium integrifolium or parts thereof or an extract or component thereof, the use of such plant material for preparing certain medicines, and a method of preparing an extract of parthenium integrifolium
DE19712201A1 (de) 1997-03-24 1998-10-01 Bodenseewerk Geraetetech Mikromechanische Spiegel-Anordnung
US6043252A (en) * 1997-05-05 2000-03-28 Icos Corporation Carboline derivatives
WO1999064420A1 (en) * 1998-06-12 1999-12-16 Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S β-CARBOLINE COMPOUNDS
AU1025899A (en) * 1998-09-16 2000-04-03 Icos Corporation Carboline derivatives as cgmp phosphodiesterase inhibitors
FR2796644B1 (fr) * 1999-07-23 2001-09-07 Adir Nouveaux derives de beta-carboline, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
UA74826C2 (en) * 2000-05-17 2006-02-15 Ortho Mcneil Pharm Inc ?-carboline derivatives as phosphodiesterase inhibitors
US7488742B2 (en) * 2000-06-15 2009-02-10 Schering Corporation Thrombin receptor antagonists
AU2001266575A1 (en) 2000-06-26 2002-01-08 Lilly Icos Llc Chemical compounds
PT1354884E (pt) 2000-12-28 2007-12-24 Ono Pharmaceutical Co Composto de ciclopenta (d) pirazolo [1,5-a] piramida como antagonista de receptor de crf
EP1360186B1 (en) * 2001-02-12 2006-11-22 Lilly Icos LLC Carboline derivatives
US7022856B2 (en) * 2001-02-12 2006-04-04 Lilly Icos Llc. Carboline derivatives
GB0108337D0 (en) * 2001-04-03 2001-05-23 Novartis Ag Organic compounds
CA2441792C (en) * 2001-04-25 2010-08-03 Lilly Icos Llc Carboline derivatives as inhibitors of phosphodiesterase 5 (pdes) for the treatment of cardiovascular diseases and erectile dysfunction
US20050009812A1 (en) 2001-10-05 2005-01-13 Takuya Seko Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists
SE520453C2 (sv) * 2001-11-01 2003-07-15 Alfa Laval Corp Ab En apparat för samtidig rening av en vätska och en gas
EP1475368A4 (en) * 2002-02-14 2006-03-29 Ono Pharmaceutical Co FUSED CORE COMPOUNDS CONTAINING N-CARBAMOYL NITROGEN AND MEDICAMENTS CONTAINING SAID COMPOUNDS AS ACTIVE INGREDIENTS
TWI329111B (en) 2002-05-24 2010-08-21 X Ceptor Therapeutics Inc Azepinoindole and pyridoindole derivatives as pharmaceutical agents
JP4671123B2 (ja) * 2003-06-23 2011-04-13 小野薬品工業株式会社 新規三環性複素環化合物
EP1706404A2 (en) 2004-01-23 2006-10-04 Chiron Corporation Tetrahydrocarboline compounds as anticancer agents
WO2005089764A1 (en) 2004-03-15 2005-09-29 Ptc Therapeutics, Inc. Carboline derivatives useful in the inhibition of angiogenesis
US7403851B2 (en) * 2004-09-30 2008-07-22 Navteq North America, Llc Method of operating a navigation system to report effects of updated portions of a geographic database
PL1829874T3 (pl) * 2004-12-22 2014-07-31 Ono Pharmaceutical Co Tricykliczny związek i jego zastosowanie

Also Published As

Publication number Publication date
WO2006068164A1 (ja) 2006-06-29
PT1829874E (pt) 2014-04-10
US8952158B2 (en) 2015-02-10
JP5652417B2 (ja) 2015-01-14
US20130252993A1 (en) 2013-09-26
US8476293B2 (en) 2013-07-02
JP2012126737A (ja) 2012-07-05
EP1829874A1 (en) 2007-09-05
US7964726B2 (en) 2011-06-21
EP1829874A4 (en) 2010-01-06
US20150105415A1 (en) 2015-04-16
US20110207700A1 (en) 2011-08-25
JPWO2006068164A1 (ja) 2008-06-12
US20080114012A1 (en) 2008-05-15
ES2459742T3 (es) 2014-05-12
JP4997976B2 (ja) 2012-08-15
EP1829874B1 (en) 2014-02-12
PL1829874T3 (pl) 2014-07-31

Similar Documents

Publication Publication Date Title
CY2019034I1 (el) 4-φαινυλαμινο-κιναζολιν-6-υλ-αμιδια
DK2079485T3 (da) Phenylpropionamidforbindelser og anvendelsen deraf
DE112005001624A5 (de) Brillengestell
DK1885716T3 (da) Thiazolderivater og anvendelse deraf
ATE520680T1 (de) Hiv-hemmende 5-heterocyclylpyrimidine
ATE392425T1 (de) Thiazolyl-dihydro-indazole
ATE459633T1 (de) Makrolide
ATE442044T1 (de) Herbizid-safener-kombination
DK1771421T3 (da) N-hydroxyamidderivater og anvendelse deraf
DK1829874T3 (da) Tricyklisk forbindelse og anvendelse deraf
DK1958948T3 (da) Pyridazinforbindelse og anvendelse deraf
DE112005000809A5 (de) Wankstabilisierungseinrichtung
DK2029561T3 (da) Tricyclisk forbindelse og farmaceutisk anvendelse deraf
DE602005024486D1 (de) Anthrapyridonfarbstoffe
DK1840121T3 (da) Glycinderivat og anvendelse heraf
DK1812072T3 (da) Benzothiazol-præparat og anvendelse deraf
AT500198B1 (de) Ladewagen
DE112005000794T5 (de) Urethanspritzpistolenanordnung
ATE389633T1 (de) Omega-phenyloctanamide
AT500249A3 (de) Scheibenegge
ATA9982004A (de) Tiefbohrbrunnen
DE112005001019A5 (de) Kunststoffschraubverschlusskappe
ATA482004A (de) Tuba-dämpfer
AT7802U3 (de) Parfum-zerstäuber
NO20044457D0 (no) Kombi-Brodd og Kombi-Brodd-System for Rollotorer