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DE69829637D1 - Vorrichtung zur intraokularen Übertragung von aktiven Wirkstoffen durch Iontophorese - Google Patents

Vorrichtung zur intraokularen Übertragung von aktiven Wirkstoffen durch Iontophorese

Info

Publication number
DE69829637D1
DE69829637D1 DE69829637T DE69829637T DE69829637D1 DE 69829637 D1 DE69829637 D1 DE 69829637D1 DE 69829637 T DE69829637 T DE 69829637T DE 69829637 T DE69829637 T DE 69829637T DE 69829637 D1 DE69829637 D1 DE 69829637D1
Authority
DE
Germany
Prior art keywords
iontophoresis
reservoir
intraocular
transmission
active agents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69829637T
Other languages
English (en)
Other versions
DE69829637T2 (de
Inventor
Jean-Marie Parel
Francine Behar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EyeGate Pharma SAS
Original Assignee
Optis SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Optis SA filed Critical Optis SA
Application granted granted Critical
Publication of DE69829637D1 publication Critical patent/DE69829637D1/de
Publication of DE69829637T2 publication Critical patent/DE69829637T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/044Shape of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448Drug reservoir

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Ophthalmology & Optometry (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Electrotherapy Devices (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
DE69829637T 1998-01-05 1998-12-17 Vorrichtung zur intraokularen Übertragung von aktiven Wirkstoffen durch Iontophorese Expired - Lifetime DE69829637T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9800009A FR2773320B1 (fr) 1998-01-05 1998-01-05 Dispositif pour le transfert intraoculaire de produits actifs par iontophorese
FR9800009 1998-01-05

Publications (2)

Publication Number Publication Date
DE69829637D1 true DE69829637D1 (de) 2005-05-12
DE69829637T2 DE69829637T2 (de) 2006-03-09

Family

ID=9521510

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69841028T Expired - Lifetime DE69841028D1 (de) 1998-01-05 1998-12-17 Vorrichtung zur okularen Iontophorese zur Verabreichung mehrerer Wirkstoffe
DE69829637T Expired - Lifetime DE69829637T2 (de) 1998-01-05 1998-12-17 Vorrichtung zur intraokularen Übertragung von aktiven Wirkstoffen durch Iontophorese

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69841028T Expired - Lifetime DE69841028D1 (de) 1998-01-05 1998-12-17 Vorrichtung zur okularen Iontophorese zur Verabreichung mehrerer Wirkstoffe

Country Status (13)

Country Link
US (1) US6154671A (de)
EP (2) EP0927560B1 (de)
JP (1) JP4308353B2 (de)
KR (1) KR100551706B1 (de)
AT (2) ATE437672T1 (de)
BR (1) BR9900009A (de)
CA (1) CA2257749C (de)
DE (2) DE69841028D1 (de)
DK (1) DK0927560T3 (de)
ES (2) ES2236880T3 (de)
FR (1) FR2773320B1 (de)
IL (1) IL127711A (de)
PT (1) PT927560E (de)

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US6319240B1 (en) * 1999-05-25 2001-11-20 Iomed, Inc. Methods and apparatus for ocular iontophoresis
US6728573B1 (en) * 2000-02-23 2004-04-27 Iomed, Inc. Ocular iontophoretic apparatus handle
US6546283B1 (en) 2000-10-18 2003-04-08 Iomed, Inc. High current density iontophoretic device and method of use thereof
US20030045830A1 (en) * 2001-04-17 2003-03-06 De Bizemont Therese Gene therapy with chimeric oligonucleotides delivered by a method comprising a step of iontophoresis
US7031776B2 (en) * 2001-06-29 2006-04-18 Optobionics Methods for improving damaged retinal cell function
US20050004625A1 (en) * 2001-06-29 2005-01-06 Chow Alan Y. Treatment of degenerative retinal disease via electrical stimulation of surface structures
US20050033202A1 (en) * 2001-06-29 2005-02-10 Chow Alan Y. Mechanically activated objects for treatment of degenerative retinal disease
US20040106965A1 (en) * 2001-06-29 2004-06-03 Chow Alan Y. Methods and apparatus for treatment of degenerative retinal disease via indirect electrical stimulation
AU2002316724A1 (en) * 2001-07-20 2003-03-03 Iomed, Inc. Ophthalmic use of 5 fluorourcil
JP2004537551A (ja) * 2001-07-20 2004-12-16 イオメド インコーポレイテッド メトトレキサートに基づく薬剤を投与することによって腫瘍性、血管原性、繊維芽細胞性及び/又は免疫抑制性眼球異常を治療する方法及びメトトレキサートに基づく薬剤を送達するための眼球イオン導入装置。
FR2830766B1 (fr) * 2001-10-12 2004-03-12 Optis France Sa Dispositif de delivrance de medicaments par iontophorese transpalpebrale
FR2830767B1 (fr) * 2001-10-12 2004-03-12 Optis France Sa Dispositif de delivrance de medicaments par iontophorese ou electroporation introculaire
FR2836832B1 (fr) 2002-03-08 2005-02-04 Optis France Sa Ensemble de connexion a usage medical pour le transfert de fluides
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US7589107B2 (en) 2003-05-19 2009-09-15 Othera Holding, Inc. Amelioration of vitrectomy-induced cataracts
US7825134B2 (en) * 2003-05-19 2010-11-02 Othera Holding, Inc. Amelioration of cataracts, macular degeneration and other ophthalmic diseases
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ZA200604403B (en) 2003-11-20 2007-09-26 Othera Pharmaceuticals Inc Amelioration of macular degeneration and other ophthalmic diseases
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WO2005115281A2 (fr) 2004-04-30 2005-12-08 Optis France Dispositif de iontophorese oculaire diminuant les irritations
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US20070282282A1 (en) * 2004-11-23 2007-12-06 Wong Edward K Jr Medical device and method for temperature control and treatment of the eye and surrounding tissues
US7229468B2 (en) * 2004-11-23 2007-06-12 Wong Jr Edward K Medical device and method for temperature control and treatment of the eye and surrounding tissues
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WO2006123248A2 (en) * 2005-04-18 2006-11-23 INSERM (Institut National de la Santé et de la Recherche Médicale) Improved methods and devices for delivering a therapeutic product to the ocular sphere of a subject
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US8755880B2 (en) * 2005-10-24 2014-06-17 Aciont, Inc. Intraocular iontophoretic device and associated methods
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US20080027371A1 (en) * 2006-07-26 2008-01-31 Higuchi John W Method and device for minimally invasive site specific ocular drug delivery
US8923961B2 (en) 2006-10-18 2014-12-30 The Cleveland Clinic Foundation Electrode assembly for delivering a therapeutic agent into ocular tissue
CN105998028A (zh) 2007-02-22 2016-10-12 科尔比制药公司 羟胺化合物及其用法
US9125807B2 (en) 2007-07-09 2015-09-08 Incept Llc Adhesive hydrogels for ophthalmic drug delivery
US8480638B2 (en) * 2007-10-04 2013-07-09 Aciont, Inc. Intraocular iontophoretic device and associated methods
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US10413506B2 (en) 2010-04-03 2019-09-17 Praful Doshi Medical devices including medicaments and methods of making and using same including enhancing comfort, enhancing drug penetration, and treatment of myopia
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Also Published As

Publication number Publication date
DE69829637T2 (de) 2006-03-09
IL127711A (en) 2004-06-20
EP1452203A2 (de) 2004-09-01
CA2257749C (en) 2009-03-24
EP0927560B1 (de) 2005-04-06
ATE292493T1 (de) 2005-04-15
KR100551706B1 (ko) 2006-07-06
DE69841028D1 (de) 2009-09-10
CA2257749A1 (en) 1999-07-05
US6154671A (en) 2000-11-28
JPH11244323A (ja) 1999-09-14
EP0927560A1 (de) 1999-07-07
DK0927560T3 (da) 2005-08-15
JP4308353B2 (ja) 2009-08-05
EP1452203A3 (de) 2004-09-08
IL127711A0 (en) 1999-10-28
ATE437672T1 (de) 2009-08-15
BR9900009A (pt) 2001-03-20
PT927560E (pt) 2005-07-29
ES2327636T3 (es) 2009-11-02
ES2236880T3 (es) 2005-07-16
EP1452203B1 (de) 2009-07-29
FR2773320A1 (fr) 1999-07-09
KR19990066875A (ko) 1999-08-16
FR2773320B1 (fr) 2000-03-03

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Owner name: EYEGATE PHARMA SAS, PARIS, FR