DE60328595D1 - Verfahren zur herstellung von cytidin 5'-diphosphatcholin - Google Patents
Verfahren zur herstellung von cytidin 5'-diphosphatcholinInfo
- Publication number
- DE60328595D1 DE60328595D1 DE60328595T DE60328595T DE60328595D1 DE 60328595 D1 DE60328595 D1 DE 60328595D1 DE 60328595 T DE60328595 T DE 60328595T DE 60328595 T DE60328595 T DE 60328595T DE 60328595 D1 DE60328595 D1 DE 60328595D1
- Authority
- DE
- Germany
- Prior art keywords
- choline
- cdp
- diphosphatcholin
- aqueous medium
- phosphorylcholine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
Landscapes
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002132917 | 2002-05-08 | ||
| PCT/JP2003/005764 WO2003095660A1 (en) | 2002-05-08 | 2003-05-08 | Process for producing cytidine 5’-diphocphate choline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DE60328595D1 true DE60328595D1 (de) | 2009-09-10 |
Family
ID=29416654
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60328595T Expired - Fee Related DE60328595D1 (de) | 2002-05-08 | 2003-05-08 | Verfahren zur herstellung von cytidin 5'-diphosphatcholin |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20050164359A1 (de) |
| EP (1) | EP1502956B1 (de) |
| JP (1) | JPWO2003095660A1 (de) |
| CN (1) | CN100513576C (de) |
| AT (1) | ATE437956T1 (de) |
| AU (1) | AU2003234789A1 (de) |
| DE (1) | DE60328595D1 (de) |
| ES (1) | ES2329566T3 (de) |
| PT (1) | PT1502956E (de) |
| WO (1) | WO2003095660A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4520219B2 (ja) * | 2004-05-28 | 2010-08-04 | 協和発酵バイオ株式会社 | ５−アミノレブリン酸の製造法 |
| TW200741005A (en) * | 2005-08-10 | 2007-11-01 | Kyowa Hakko Kogyo Kk | A purification method of cytidine diphosphate |
| WO2007023830A1 (ja) * | 2005-08-23 | 2007-03-01 | Kyowa Hakko Kogyo Co., Ltd. | シチジンジリン酸コリンの製造法 |
| US8288437B2 (en) * | 2008-07-24 | 2012-10-16 | Valent Biosciences Corporation | Salts, aqueous liquid compositions containing salts of abscisic acid analogs and methods of their preparation |
| US9637746B2 (en) | 2008-12-15 | 2017-05-02 | Greenlight Biosciences, Inc. | Methods for control of flux in metabolic pathways |
| ES2718844T3 (es) | 2010-05-07 | 2019-07-04 | Greenlight Biosciences Inc | Métodos para controlar el flujo en rutas metabólicas mediante la reubicación de enzimas |
| DK3219796T3 (da) | 2010-08-31 | 2020-12-21 | Greenlight Biosciences Inc | Fremgangsmåder til kontrol af strømningen i metaboliske reaktionsveje ved hjælp af proteasemanipulation |
| SG2014014377A (en) | 2011-09-09 | 2014-05-29 | Greenlight Biosciences Inc | Cell-free preparation of carbapenems |
| SG11201600898YA (en) | 2013-08-05 | 2016-03-30 | Greenlight Biosciences Inc | Engineered proteins with a protease cleavage site |
| MY193444A (en) | 2015-03-30 | 2022-10-13 | Greenlight Biosciences Inc | Cell-free production of ribonucleic acid |
| KR102536687B1 (ko) | 2016-04-06 | 2023-05-25 | 그린라이트 바이오사이언시스, 아이엔씨. | 리보핵산의 무세포 생산 |
| CN109207415B (zh) * | 2017-07-07 | 2022-09-16 | 苏州华赛生物工程技术有限公司 | 一种生产胞二磷胆碱的重组微生物及生产胞二磷胆碱的方法 |
| JP2020536570A (ja) | 2017-10-11 | 2020-12-17 | グリーンライト バイオサイエンシーズ インコーポレーテッドＧｒｅｅｎｌｉｇｈｔ Ｂｉｏｓｃｉｅｎｃｅｓ，Ｉｎｃ． | ヌクレオシド三リン酸およびリボ核酸の生成のための方法および組成物 |
| CN107488603A (zh) * | 2017-10-19 | 2017-12-19 | 南通秋之友生物科技有限公司 | 一种过表达磷酸胆碱胞苷转移酶酿酒酵母基因工程菌及构建方法和应用 |
| CN108424859B (zh) * | 2017-11-23 | 2021-09-10 | 华东理工大学 | 生产胞磷胆碱的基因工程菌的构建与应用 |
| WO2023038128A1 (ja) | 2021-09-10 | 2023-03-16 | 協和発酵バイオ株式会社 | Ｃｄｐ－コリンの製造に用いる組換え微生物及び該組換え微生物を用いるｃｄｐ－コリンの製造方法 |
| CN116790466B (zh) * | 2023-07-19 | 2023-11-03 | 山东理工大学 | 一种工程改造枯草芽孢杆菌发酵生产胞磷胆碱的方法 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4840758B1 (de) | 1969-03-24 | 1973-12-03 | ||
| JPS58110600A (ja) | 1981-12-25 | 1983-07-01 | Kyowa Hakko Kogyo Co Ltd | ヒトβ型インタ−フエロン遺伝子を含む組みかえ体プラスミド |
| JPS60221091A (ja) | 1983-12-21 | 1985-11-05 | Kyowa Hakko Kogyo Co Ltd | 新規プロモ−タ− |
| JP2564268B2 (ja) | 1985-08-28 | 1996-12-18 | 協和醗酵工業株式会社 | 融合抗原ポリペプチド |
| JPH0710235B2 (ja) * | 1987-10-19 | 1995-02-08 | 協和醗酵工業株式会社 | 発酵法によるオロット酸の製造法 |
| JPH0322979A (ja) | 1989-06-19 | 1991-01-31 | Kyowa Hakko Kogyo Co Ltd | 新規プラスミノーゲン活性化因子 |
| KR0177841B1 (ko) * | 1992-01-30 | 1999-04-01 | 나까무라 간노스께 | 시티딘 디인산 콜린의 제조방법 |
| JP3369236B2 (ja) * | 1992-01-30 | 2003-01-20 | 協和醗酵工業株式会社 | シチジンジリン酸コリンの製造法 |
| WO1999049073A1 (fr) | 1998-03-20 | 1999-09-30 | Yamasa Corporation | Procede de production de cytidine 5'-diphosphate choline |
| JP3822006B2 (ja) | 1999-10-08 | 2006-09-13 | ヤマサ醤油株式会社 | シチジン５’−ジリン酸コリンの製造法 |
| JP2001238691A (ja) * | 2000-02-29 | 2001-09-04 | Kyowa Hakko Kogyo Co Ltd | ヌクレオシド５’−三リン酸の製造方法 |
| JP2002045185A (ja) * | 2000-08-02 | 2002-02-12 | Kyowa Hakko Kogyo Co Ltd | Ｆ０Ｆ１−ＡＴＰａｓｅおよび該酵素をコードするＤＮＡ |
-
2003
- 2003-05-08 DE DE60328595T patent/DE60328595D1/de not_active Expired - Fee Related
- 2003-05-08 PT PT03728046T patent/PT1502956E/pt unknown
- 2003-05-08 ES ES03728046T patent/ES2329566T3/es not_active Expired - Lifetime
- 2003-05-08 WO PCT/JP2003/005764 patent/WO2003095660A1/ja active Application Filing
- 2003-05-08 EP EP03728046A patent/EP1502956B1/de not_active Expired - Lifetime
- 2003-05-08 US US10/513,718 patent/US20050164359A1/en not_active Abandoned
- 2003-05-08 CN CNB038104350A patent/CN100513576C/zh not_active Expired - Fee Related
- 2003-05-08 JP JP2004503650A patent/JPWO2003095660A1/ja active Pending
- 2003-05-08 AT AT03728046T patent/ATE437956T1/de not_active IP Right Cessation
- 2003-05-08 AU AU2003234789A patent/AU2003234789A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ATE437956T1 (de) | 2009-08-15 |
| PT1502956E (pt) | 2009-08-31 |
| EP1502956A1 (de) | 2005-02-02 |
| WO2003095660A1 (en) | 2003-11-20 |
| AU2003234789A1 (en) | 2003-11-11 |
| EP1502956A4 (de) | 2007-08-22 |
| ES2329566T3 (es) | 2009-11-27 |
| CN1653188A (zh) | 2005-08-10 |
| JPWO2003095660A1 (ja) | 2005-09-15 |
| CN100513576C (zh) | 2009-07-15 |
| EP1502956B1 (de) | 2009-07-29 |
| US20050164359A1 (en) | 2005-07-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |