ATE265421T1 - Verfahren zur herstellung von midodrin - Google Patents
Verfahren zur herstellung von midodrinInfo
- Publication number
- ATE265421T1 ATE265421T1 AT02002042T AT02002042T ATE265421T1 AT E265421 T1 ATE265421 T1 AT E265421T1 AT 02002042 T AT02002042 T AT 02002042T AT 02002042 T AT02002042 T AT 02002042T AT E265421 T1 ATE265421 T1 AT E265421T1
- Authority
- AT
- Austria
- Prior art keywords
- midodrin
- producing
- dimethoxyphenyl
- chem
- formula
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- PTKSEFOSCHHMPD-UHFFFAOYSA-N midodrine Chemical compound COC1=CC=C(OC)C(C(O)CNC(=O)CN)=C1 PTKSEFOSCHHMPD-UHFFFAOYSA-N 0.000 title 1
- 229960001094 midodrine Drugs 0.000 title 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 238000007327 hydrogenolysis reaction Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL14165501A IL141655A0 (en) | 2001-02-26 | 2001-02-26 | A process for the preparation of midodrine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE265421T1 true ATE265421T1 (de) | 2004-05-15 |
Family
ID=11075177
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02002042T ATE265421T1 (de) | 2001-02-26 | 2002-02-07 | Verfahren zur herstellung von midodrin |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6444851B1 (de) |
| EP (1) | EP1234817B1 (de) |
| JP (1) | JP2002255915A (de) |
| AT (1) | ATE265421T1 (de) |
| CA (1) | CA2366311A1 (de) |
| CZ (1) | CZ2002138A3 (de) |
| DE (1) | DE60200406T2 (de) |
| HU (1) | HUP0200034A2 (de) |
| IL (1) | IL141655A0 (de) |
| PL (1) | PL352455A1 (de) |
| PT (1) | PT1234817E (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2421550C (en) * | 2003-03-11 | 2008-06-03 | Brantford Chemicals Inc. | Process for the preparation of midodrine, pharmaceutically-acceptable salts thereof and intermediates |
| US20070082070A1 (en) * | 2005-10-11 | 2007-04-12 | Stookey Evangeline L | Treating skin disorders |
| CN101641344A (zh) * | 2007-03-30 | 2010-02-03 | 巴斯夫欧洲公司 | 从多氧基二烷基醚制备环状甲醛衍生物的方法 |
| KR101356471B1 (ko) | 2011-12-09 | 2014-01-29 | 고려대학교 산학협력단 | 고혈압 예방 및 치료용 화합물 |
| US12032578B1 (en) | 2023-01-24 | 2024-07-09 | Sap Se | Data compression, store, and search system |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT241435B (de) * | 1963-06-11 | 1965-07-26 | Chemie Linz Ag | Verfahren zur Herstellung von neuen Phenylalkanolaminderivaten und deren Salzen |
| AT336584B (de) * | 1975-02-25 | 1977-05-10 | Chemie Linz Ag | Verfahren zur herstellung von 1-phenyl-2-glycinamidoathanolen- (1) und von deren salzen |
| JPH07285921A (ja) * | 1994-04-15 | 1995-10-31 | Sanyo Kagaku Kenkyusho:Kk | ２−アミノ−Ｎ−（β−ヒドロキシフェネチル）アセトアミド誘導体の製造方法 |
-
2001
- 2001-02-26 IL IL14165501A patent/IL141655A0/xx unknown
- 2001-12-31 CA CA002366311A patent/CA2366311A1/en not_active Abandoned
-
2002
- 2002-01-04 HU HU0200034A patent/HUP0200034A2/hu unknown
- 2002-01-09 US US10/040,385 patent/US6444851B1/en not_active Expired - Fee Related
- 2002-01-11 CZ CZ2002138A patent/CZ2002138A3/cs unknown
- 2002-02-07 EP EP02002042A patent/EP1234817B1/de not_active Expired - Lifetime
- 2002-02-07 PT PT02002042T patent/PT1234817E/pt unknown
- 2002-02-07 JP JP2002030646A patent/JP2002255915A/ja active Pending
- 2002-02-07 DE DE60200406T patent/DE60200406T2/de not_active Expired - Lifetime
- 2002-02-07 AT AT02002042T patent/ATE265421T1/de not_active IP Right Cessation
- 2002-02-25 PL PL02352455A patent/PL352455A1/xx not_active IP Right Cessation
- 2002-07-30 US US10/206,968 patent/US6610886B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CZ2002138A3 (cs) | 2002-10-16 |
| DE60200406D1 (de) | 2004-06-03 |
| US20020193635A1 (en) | 2002-12-19 |
| EP1234817A1 (de) | 2002-08-28 |
| JP2002255915A (ja) | 2002-09-11 |
| US6610886B2 (en) | 2003-08-26 |
| HU0200034D0 (en) | 2002-03-28 |
| DE60200406T2 (de) | 2004-09-02 |
| IL141655A0 (en) | 2002-03-10 |
| PT1234817E (pt) | 2004-08-31 |
| CA2366311A1 (en) | 2002-08-26 |
| US6444851B1 (en) | 2002-09-03 |
| PL352455A1 (en) | 2002-09-09 |
| HUP0200034A2 (hu) | 2002-12-28 |
| US20020128511A1 (en) | 2002-09-12 |
| EP1234817B1 (de) | 2004-04-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1234817 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |