DE60239842D1 - Verfahren zur Herstellung von 10,11-dihydro-10-oxo-5h-dibenzoÄb,fÜazepin-5-carboxamid - Google Patents

Verfahren zur Herstellung von 10,11-dihydro-10-oxo-5h-dibenzoÄb,fÜazepin-5-carboxamid

Info

Publication number: DE60239842D1
Authority: DE; Germany
Prior art keywords: fazexpin; dibenzoab; carboxamide; dihydro; oxo
Prior art date: 2001-05-25
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60239842T

Other languages

English (en)

Inventor

David Alexander Learmonth

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bial Portela and Cia SA

Original Assignee

Bial Portela and Cia SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-05-25

Filing date

2002-05-22

Publication date

2011-06-01

2002-05-22 Application filed by Bial Portela and Cia SA filed Critical Bial Portela and Cia SA

2011-06-01 Application granted granted Critical

2011-06-01 Publication of DE60239842D1 publication Critical patent/DE60239842D1/de

2022-05-23 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/18—Dibenzazepines; Hydrogenated dibenzazepines
- C07D223/22—Dibenz [b, f] azepines; Hydrogenated dibenz [b, f] azepines

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Neurosurgery (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Epoxy Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Catalysts (AREA)

DE60239842T 2001-05-25 2002-05-22 Verfahren zur Herstellung von 10,11-dihydro-10-oxo-5h-dibenzoÄb,fÜazepin-5-carboxamid Expired - Lifetime DE60239842D1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GBGB0112812.3A GB0112812D0 (en)	2001-05-25	2001-05-25	Mthd for preparation of 10, 11-dihydro-10-hydroxy-5H-dibenz/B,F/azepine-5-c arboxamide and 10,11-dihydro-10-oxo-5H-dibenz/B,F/azepine-5-carb oxamide therefrom

Publications (1)

Publication Number	Publication Date
DE60239842D1 true DE60239842D1 (de)	2011-06-01

Family

ID=9915332

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DE60239842T Expired - Lifetime DE60239842D1 (de)	2001-05-25	2002-05-22	Verfahren zur Herstellung von 10,11-dihydro-10-oxo-5h-dibenzoÄb,fÜazepin-5-carboxamid
DE60227517T Expired - Lifetime DE60227517D1 (de)	2001-05-25	2002-05-22	Verfahren zur herstellung von 10,11 dihydro 10 hydroxy 5h-dibenz/b,f/azepin-5-carbonsäureamid und 10,11 dihydro 10 oxo-5h-dibenz/b,f/azepin-5 carbonsäureamid

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DE60227517T Expired - Lifetime DE60227517D1 (de)	2001-05-25	2002-05-22	Verfahren zur herstellung von 10,11 dihydro 10 hydroxy 5h-dibenz/b,f/azepin-5-carbonsäureamid und 10,11 dihydro 10 oxo-5h-dibenz/b,f/azepin-5 carbonsäureamid

Country Status (23)

Country	Link
US (1)	US7241886B2 (de)
EP (2)	EP1958938B1 (de)
JP (3)	JP4323309B2 (de)
KR (1)	KR100931916B1 (de)
CN (2)	CN101172967A (de)
AR (1)	AR035460A1 (de)
AT (2)	ATE506351T1 (de)
AU (2)	AU2002307863B8 (de)
BR (1)	BR0210019A (de)
CA (2)	CA2750876C (de)
CY (3)	CY1108345T1 (de)
CZ (1)	CZ303130B6 (de)
DE (2)	DE60239842D1 (de)
DK (2)	DK1399424T3 (de)
ES (2)	ES2362688T3 (de)
GB (1)	GB0112812D0 (de)
HU (1)	HU230019B1 (de)
LU (1)	LU91603I2 (de)
MX (1)	MXPA03010793A (de)
PL (1)	PL215305B1 (de)
RU (2)	RU2311411C2 (de)
SI (1)	SI1399424T1 (de)
WO (1)	WO2002096881A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0303615D0 (en) *	2003-02-17	2003-03-19	Novartis Ag	Use of organic compounds
ITMI20042230A1 (it)	2004-11-19	2005-02-19	Farchemia Srl	Procedimento per la preparazione della 10,11-diidro-10 idrossi-5h-dibenz-b,f-azepin-5carbossiammide
ITMI20042291A1 (it) *	2004-11-26	2005-02-26	Farchema S R L	Procedimento per la preparazione della -s-piu-10,11-diidro-10-idrossi-5h-dibenz-b,f-azepin-5-carbossiammide
GB2422149A (en)	2005-01-14	2006-07-19	Portela & Ca Sa	Process for the preparation of 10,11-dihydro-10-hydroxy-5H-dibenz[b,f]azepine-5-carboxamide
US20060252745A1 (en)	2005-05-06	2006-11-09	Almeida Jose L D	Methods of preparing pharmaceutical compositions comprising eslicarbazepine acetate and methods of use
GB0515690D0 (en)	2005-07-29	2005-09-07	Portela & Ca Sa	Asymmetric catalytic reduction
GB0517740D0 (en) *	2005-08-31	2005-10-12	Novartis Ag	Organic compounds
GB0700773D0 (en)	2007-01-15	2007-02-21	Portela & Ca Sa	Drug therapies
US8372431B2 (en)	2007-10-26	2013-02-12	Bial-Portela & C.A., S.A.	Pharmaceutical composition comprising licarbazepine acetate
CA2769181C (en)	2009-07-27	2017-11-28	Bial-Portela & Ca., S.A.	Use of 5h-dibenz / b, f/ azepine-5-carboxamide derivatives for treating fibromyalgia
US20150065704A1 (en)	2011-07-13	2015-03-05	Ketan Hirpara	Process for the preparation and purification of eslicarbazepine acetate and intermediates thereof
IN2015DN02296A (de)	2012-09-26	2015-08-21	Ranbaxy Lab Ltd
EP3350343B1 (de)	2015-09-16	2020-04-22	Petaomics, Inc.	Verfahren und zusammensetzungen zur genomischen zielanreicherung und selektiven dna-sequenzierung
CN111943347B (zh) *	2020-07-16	2022-08-30	同济大学	一种铜离子活化过氧乙酸去除废水中卡马西平的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS5439390B2 (de) *	1971-09-30	1979-11-27
BE789320A (fr) *	1971-09-30	1973-03-27	Takeda Chemical Industries Ltd	Derives de dibenzoxirenazepine
CH633271A5 (en) *	1978-04-18	1982-11-30	Ciba Geigy Ag	Process for the rearrangement of 10,11-epoxy-10,11-dihydro-5H-dibenz[b,f]azepines to give 10-oxo-10,11-dihydro-5H-dibenz(b,f)azepines
CH642950A5 (en) *	1979-10-30	1984-05-15	Ciba Geigy Ag	Process for the preparation of 10-oxo-10,11-dihydro-5H-dibenz[b,f]azepine-5-carboxamide
IT1272897B (it) *	1995-01-13	1997-07-01	I F C Iniziative Finanziaarie	Processo per la produzione di 10-oxo-10,11-diidro-sh- -dibenz(b,f) azepin-5-carbossiammide
PT101732B (pt) *	1995-06-30	1997-12-31	Portela & Ca Sa	Novas di-hidrodibenzo<b,f>azepinas substituidas processo para a sua preparacao composicoes farmaceuticas que as contem e utilizacao dos novos compostos na preparacao de composicoes farmaceuticas empregues em doencas do sistema nervoso
PT101876B (pt) *	1996-05-27	1999-09-30	Portela & Ca Sa	Novos derivados de 10,11-di-hidro-10-oxo-5h-dibenzo(b,f)azepina-5-carboxamida
AT408224B (de) *	1999-03-15	2001-09-25	Dsm Fine Chem Austria Gmbh	Verfahren zur herstellung von oxcarbazepin

2001
- 2001-05-25 GB GBGB0112812.3A patent/GB0112812D0/en not_active Ceased
2002
- 2002-05-22 WO PCT/GB2002/002356 patent/WO2002096881A1/en active IP Right Grant
- 2002-05-22 DE DE60239842T patent/DE60239842D1/de not_active Expired - Lifetime
- 2002-05-22 MX MXPA03010793A patent/MXPA03010793A/es active IP Right Grant
- 2002-05-22 JP JP2003500061A patent/JP4323309B2/ja not_active Expired - Fee Related
- 2002-05-22 KR KR1020037015323A patent/KR100931916B1/ko not_active Expired - Fee Related
- 2002-05-22 CA CA2750876A patent/CA2750876C/en not_active Expired - Fee Related
- 2002-05-22 CA CA2448094A patent/CA2448094C/en not_active Expired - Lifetime
- 2002-05-22 ES ES08075527T patent/ES2362688T3/es not_active Expired - Lifetime
- 2002-05-22 RU RU2003137224/04A patent/RU2311411C2/ru active
- 2002-05-22 AU AU2002307863A patent/AU2002307863B8/en not_active Ceased
- 2002-05-22 EP EP08075527A patent/EP1958938B1/de not_active Expired - Lifetime
- 2002-05-22 CN CNA2007101939981A patent/CN101172967A/zh active Pending
- 2002-05-22 DK DK02774050T patent/DK1399424T3/da active
- 2002-05-22 CN CN028105915A patent/CN1511141B/zh not_active Expired - Fee Related
- 2002-05-22 DK DK08075527.5T patent/DK1958938T3/da active
- 2002-05-22 EP EP02774050A patent/EP1399424B8/de not_active Expired - Lifetime
- 2002-05-22 US US10/478,770 patent/US7241886B2/en not_active Expired - Lifetime
- 2002-05-22 SI SI200230717T patent/SI1399424T1/sl unknown
- 2002-05-22 BR BR0210019-3A patent/BR0210019A/pt active Search and Examination
- 2002-05-22 DE DE60227517T patent/DE60227517D1/de not_active Expired - Lifetime
- 2002-05-22 ES ES02774050T patent/ES2305299T3/es not_active Expired - Lifetime
- 2002-05-22 PL PL366993A patent/PL215305B1/pl unknown
- 2002-05-22 AT AT08075527T patent/ATE506351T1/de active
- 2002-05-22 AT AT02774050T patent/ATE400560T1/de active
- 2002-05-22 CZ CZ20033203A patent/CZ303130B6/cs not_active IP Right Cessation
- 2002-05-22 HU HU0400296A patent/HU230019B1/hu unknown
- 2002-05-24 AR ARP020101958A patent/AR035460A1/es not_active Application Discontinuation
2007
- 2007-06-01 RU RU2007120532/04A patent/RU2449992C2/ru not_active IP Right Cessation
- 2007-10-04 AU AU2007221834A patent/AU2007221834B2/en not_active Ceased
2008
- 2008-08-05 JP JP2008201613A patent/JP2009057376A/ja active Pending
- 2008-09-17 CY CY20081100998T patent/CY1108345T1/el unknown
2009
- 2009-03-09 JP JP2009054515A patent/JP5280252B2/ja not_active Expired - Fee Related
- 2009-08-28 LU LU91603C patent/LU91603I2/fr unknown
- 2009-10-19 CY CY2009017C patent/CY2009017I2/el unknown
2011
- 2011-05-27 CY CY20111100515T patent/CY1111492T1/el unknown

Also Published As

Publication number	Publication date
ATE400560T1 (de)	2008-07-15
CZ20033203A3 (cs)	2004-06-16
SI1399424T1 (sl)	2008-10-31
AU2002307863B2 (en)	2007-09-27
KR20040030626A (ko)	2004-04-09
AU2007221834A1 (en)	2007-10-25
EP1958938A2 (de)	2008-08-20
HU230019B1 (hu)	2015-05-28
CA2750876A1 (en)	2002-12-05
RU2311411C2 (ru)	2007-11-27
CA2448094C (en)	2011-11-01
CN1511141A (zh)	2004-07-07
LU91603I2 (fr)	2009-10-28
RU2003137224A (ru)	2005-05-27
EP1958938B1 (de)	2011-04-20
DK1958938T3 (da)	2011-07-25
BR0210019A (pt)	2004-08-10
ATE506351T1 (de)	2011-05-15
US7241886B2 (en)	2007-07-10
JP2009167194A (ja)	2009-07-30
KR100931916B1 (ko)	2009-12-15
CN101172967A (zh)	2008-05-07
CY1108345T1 (el)	2012-01-25
MXPA03010793A (es)	2004-07-01
RU2007120532A (ru)	2008-12-10
CA2448094A1 (en)	2002-12-05
EP1958938A3 (de)	2008-09-03
PL366993A1 (en)	2005-02-07
CY2009017I1 (el)	2012-01-25
CY1111492T1 (el)	2015-08-05
US20040158060A1 (en)	2004-08-12
PL215305B1 (pl)	2013-11-29
AU2002307863B8 (en)	2007-10-18
EP1399424A1 (de)	2004-03-24
EP1399424B1 (de)	2008-07-09
JP2004532263A (ja)	2004-10-21
CA2750876C (en)	2014-10-28
EP1399424B8 (de)	2008-10-01
AR035460A1 (es)	2004-05-26
JP4323309B2 (ja)	2009-09-02
CY2009017I2 (el)	2012-01-25
DK1399424T3 (da)	2008-09-08
CN1511141B (zh)	2011-06-08
JP2009057376A (ja)	2009-03-19
HUP0400296A3 (en)	2008-03-28
AU2007221834B2 (en)	2009-02-05
ES2305299T3 (es)	2008-11-01
WO2002096881A1 (en)	2002-12-05
ES2362688T3 (es)	2011-07-11
GB0112812D0 (en)	2001-07-18
CZ303130B6 (cs)	2012-04-18
RU2449992C2 (ru)	2012-05-10
DE60227517D1 (de)	2008-08-21
HUP0400296A2 (hu)	2004-08-30
JP5280252B2 (ja)	2013-09-04
WO2002096881A8 (en)	2003-02-27

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