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DE60116874D1 - Verfahren zur herstellung von (r)-2-alkyl-3-phenyl-1-propanolen - Google Patents

Verfahren zur herstellung von (r)-2-alkyl-3-phenyl-1-propanolen

Info

Publication number
DE60116874D1
DE60116874D1 DE60116874T DE60116874T DE60116874D1 DE 60116874 D1 DE60116874 D1 DE 60116874D1 DE 60116874 T DE60116874 T DE 60116874T DE 60116874 T DE60116874 T DE 60116874T DE 60116874 D1 DE60116874 D1 DE 60116874D1
Authority
DE
Germany
Prior art keywords
propanolene
phenyl
alkyl
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60116874T
Other languages
English (en)
Other versions
DE60116874T2 (de
Inventor
Peter Herold
Stefan Stutz
Felix Spindler
Walter Weissesteiner
Thomas Sturm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Speedel Pharma AG
Original Assignee
Speedel Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Speedel Pharma AG filed Critical Speedel Pharma AG
Publication of DE60116874D1 publication Critical patent/DE60116874D1/de
Application granted granted Critical
Publication of DE60116874T2 publication Critical patent/DE60116874T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/17—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734—Ethers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE60116874T 2000-07-03 2001-06-26 Verfahren zur herstellung von (r)-2-alkyl-3-phenyl-1-propanolen Expired - Lifetime DE60116874T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH13182000 2000-07-03
CH131800 2000-07-03
PCT/CH2001/000398 WO2002002487A1 (en) 2000-07-03 2001-06-26 Process for the preparation of (r)-2-alkyl-3-phenyl-1-propanols

Publications (2)

Publication Number Publication Date
DE60116874D1 true DE60116874D1 (de) 2006-04-13
DE60116874T2 DE60116874T2 (de) 2006-11-02

Family

ID=4565375

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60116874T Expired - Lifetime DE60116874T2 (de) 2000-07-03 2001-06-26 Verfahren zur herstellung von (r)-2-alkyl-3-phenyl-1-propanolen

Country Status (12)

Country Link
US (1) US6881868B2 (de)
EP (1) EP1296912B1 (de)
JP (1) JP4841799B2 (de)
CN (1) CN1293026C (de)
AR (1) AR029558A1 (de)
AT (1) ATE316518T1 (de)
AU (1) AU2001273762A1 (de)
BR (1) BR0112128A (de)
CA (1) CA2414844C (de)
DE (1) DE60116874T2 (de)
TW (1) TW575537B (de)
WO (1) WO2002002487A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004101844A1 (en) * 2002-12-18 2004-11-25 Cardinal Cg Company Plasma-enhanced film deposition
DE102005052195A1 (de) 2005-10-28 2007-05-03 Reuter Chemischer Apparatebau Kg Verfahren zur Herstellung von chiralen Octensäurederivaten
WO2007085651A1 (en) * 2006-01-30 2007-08-02 Speedel Experimenta Ag Process for the stereoselective preparation of alcohols from alpha, beta- insaturated compounds
EP1921069A1 (de) * 2006-11-08 2008-05-14 Speedel Experimenta AG Verfahren zur Herstellung von 2-Alkyl-3-heterocyclyl-prop-2-en-1-olen
TW200837046A (en) * 2006-11-08 2008-09-16 Speedel Experimenta Ag Process for preparing organic compounds
EP1939182A1 (de) * 2006-12-22 2008-07-02 Speedel Experimenta AG Verfahren zur Herstellung von (R oder S)-2-Alkyl-3-heterocyclyl-1-propanolen
EP1958666A1 (de) 2007-02-13 2008-08-20 Speedel Experimenta AG Heterozyklische substituierte Alkanamide als therapeutische Verbindungen
AR065792A1 (es) * 2007-03-21 2009-07-01 Speedel Experimenta Ag Proceso para preparar (r o s) -5- (1 -azido-3-(6-metoxi-5-(3-metoxi-propoxi) -piridin-3-ilmetil) -4-metil- pentil) -3-alquil-dihidro-furan-2-ona
EP2178816A1 (de) * 2007-07-11 2010-04-28 DSM Fine Chemicals Austria Nfg GmbH & Co KG Alpha-substituierte ?,?-ungesättigte e- oder z-aldehyde, deren verwendung und verfahren zu ihrer herstellung
CN101801903A (zh) * 2007-07-11 2010-08-11 帝斯曼知识产权资产管理有限公司 饱和醛的制备
DE102007049039A1 (de) 2007-10-11 2009-04-16 Reuter Chemischer Apparatebau Kg Verfahren zur Herstellung von 8-Hydrazino-8-Aryl-Octanoylderivaten und deren Verwendung
WO2011051853A1 (en) 2009-10-29 2011-05-05 CarboDesign LLC Manufacturing process for preparing enaniomerically pure 8- aryloctanoic acid derivatives such as aliskiren
TW201202178A (en) 2010-06-04 2012-01-16 Chemo Iberica Sa Process for producing Aliskiren
US8703976B2 (en) 2011-10-02 2014-04-22 Milan Soukup Manufacturing process for 8-aryloctanoic acids such as Aliskiren

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2709268A1 (de) * 1977-03-03 1978-09-07 Merck Patent Gmbh Diphenylaetherderivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen enthaltend diese verbindungen
ZA838831B (en) * 1982-12-31 1984-07-25 Fujisawa Pharmaceutical Co New nitro aliphatic compounds,process for preparation thereof and use thereof
JPH0694441B2 (ja) * 1992-11-18 1994-11-24 和光純薬工業株式会社 ＤＬ−スレオ−２−（３，４−ジ低級アルキルオキシ−α−ヒドロキシベンジル）イソ吉草酸アルキル及びその製造法
MY119161A (en) * 1994-04-18 2005-04-30 Novartis Ag Delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides with enzyme especially renin inhibiting activities
DE19516968A1 (de) * 1995-05-12 1996-11-14 Basf Ag Optisch aktive Phosphine, deren Herstellung, deren Metallkomplexe und Anwendung in der asymmetrischen Synthese
ATE546425T1 (de) * 2000-07-03 2012-03-15 Novartis Ag Herstellung von (r)-2-alkyl-3-phenylpropionsäuren

Also Published As

Publication number Publication date
EP1296912A1 (de) 2003-04-02
US20040092766A1 (en) 2004-05-13
US6881868B2 (en) 2005-04-19
AU2001273762A1 (en) 2002-01-14
BR0112128A (pt) 2003-05-13
CA2414844A1 (en) 2002-01-10
JP4841799B2 (ja) 2011-12-21
WO2002002487A1 (en) 2002-01-10
DE60116874T2 (de) 2006-11-02
ATE316518T1 (de) 2006-02-15
AR029558A1 (es) 2003-07-02
CA2414844C (en) 2010-05-11
CN1293026C (zh) 2007-01-03
JP2004502656A (ja) 2004-01-29
TW575537B (en) 2004-02-11
EP1296912B1 (de) 2006-01-25
CN1440374A (zh) 2003-09-03

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Legal Events

Date Code Title Description
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC