DE60115863D1 - Beta 1, 2-xylosyltransferase gen aus arabidopsis - Google Patents
Beta 1, 2-xylosyltransferase gen aus arabidopsisInfo
- Publication number
- DE60115863D1 DE60115863D1 DE60115863T DE60115863T DE60115863D1 DE 60115863 D1 DE60115863 D1 DE 60115863D1 DE 60115863 T DE60115863 T DE 60115863T DE 60115863 T DE60115863 T DE 60115863T DE 60115863 D1 DE60115863 D1 DE 60115863D1
- Authority
- DE
- Germany
- Prior art keywords
- arabidopsis
- beta
- less
- glycoprotein
- human protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241000219194 Arabidopsis Species 0.000 title 1
- 108010044310 beta 1,2-xylosyltransferase Proteins 0.000 title 1
- 102000003886 Glycoproteins Human genes 0.000 abstract 4
- 108090000288 Glycoproteins Proteins 0.000 abstract 4
- 102000003839 Human Proteins Human genes 0.000 abstract 2
- 108090000144 Human Proteins Proteins 0.000 abstract 2
- 108010065282 UDP xylose-protein xylosyltransferase Proteins 0.000 abstract 1
- 102000010199 Xylosyltransferases Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 125000000969 xylosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)CO1)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/005—Glycopeptides, glycoproteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1077—Pentosyltransferases (2.4.2)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/02—Pentosyltransferases (2.4.2)
- C12Y204/02038—Glycoprotein 2-beta-D-xylosyltransferase (2.4.2.38)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01024—Alpha-mannosidase (3.2.1.24)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/0105—Alpha-N-acetylglucosaminidase (3.2.1.50)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01052—Beta-N-acetylhexosaminidase (3.2.1.52)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT0035500A AT409381B (de) | 2000-03-03 | 2000-03-03 | Xylosyltransferase-gen |
AT3552000 | 2000-03-03 | ||
PCT/EP2001/002352 WO2001064901A1 (en) | 2000-03-03 | 2001-03-02 | Beta 1, 2-xylosyltransferase-gene from arabidopsis |
EP01919367.1A EP1263968B2 (de) | 2000-03-03 | 2001-03-02 | Beta 1, 2-xylosyltransferase gen aus arabidopsis |
Publications (3)
Publication Number | Publication Date |
---|---|
DE60115863D1 true DE60115863D1 (de) | 2006-01-19 |
DE60115863T2 DE60115863T2 (de) | 2006-08-10 |
DE60115863T3 DE60115863T3 (de) | 2015-01-22 |
Family
ID=3672559
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60115863.6T Expired - Lifetime DE60115863T3 (de) | 2000-03-03 | 2001-03-02 | Beta 1, 2-xylosyltransferase gen aus arabidopsis |
Country Status (12)
Country | Link |
---|---|
US (3) | US7205137B2 (de) |
EP (2) | EP1263968B2 (de) |
JP (2) | JP5279976B2 (de) |
KR (5) | KR100861437B1 (de) |
AT (2) | AT409381B (de) |
AU (1) | AU781010B2 (de) |
CA (1) | CA2402015C (de) |
DE (1) | DE60115863T3 (de) |
DK (2) | DK1621633T3 (de) |
ES (2) | ES2460672T3 (de) |
PT (1) | PT1621633E (de) |
WO (1) | WO2001064901A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MXPA01005778A (es) | 1998-12-09 | 2003-07-21 | Dow Chemical Co | Un metodo para fabricar glicoproteinas que tienen glicosilacion de tipo humano. |
PT1772518E (pt) | 1999-10-26 | 2010-10-28 | Stichting Dienst Landbouwkundi | Glicosilação do tipo mamífero em plantas |
ZA200306406B (en) | 2001-01-19 | 2004-09-06 | Dow Chemical Co | Method for secretory production of glycoprotein having human-type sugar chain using plant cell. |
KR101060361B1 (ko) | 2002-03-19 | 2011-08-29 | 스티칭 디엔스트 랜드보위쿤디그 온데조에크 | 식물에서 글리칸 프로세싱의 최적화 |
NZ534881A (en) | 2002-03-19 | 2006-09-29 | Plant Res Internat B | Mammalian GnTIII expression in plants |
AR042145A1 (es) | 2002-11-27 | 2005-06-08 | Dow Agrociences Llc | Produccion de inmunoglobulinas en plantas con una fucocilacion reducida |
EP1510584B1 (de) | 2003-08-11 | 2009-03-18 | Greenovation Biotech GmbH | Promoter Sequenzen aus Moos und dessen Verwendung |
NZ598048A (en) | 2006-01-17 | 2013-05-31 | Synthon Biopharmaceuticals Bv | Compositions and methods for humanization and optimization of n-glycans in plants |
US20090060921A1 (en) * | 2006-01-17 | 2009-03-05 | Biolex Therapeutics, Inc. | Glycan-optimized anti-cd20 antibodies |
US20100287657A1 (en) * | 2006-03-23 | 2010-11-11 | Bayer Bioscience N.V. | Novel Nucleotide Sequences Encoding Nicotiana Beta-1,2-Xylosyltransferase |
KR101460953B1 (ko) | 2007-04-17 | 2014-11-13 | 스티칭 디엔스트 랜드보위쿤디그 온데조에크 | 비-포유동물 글리코실트랜스퍼라제의 발현에 의한 식물에서의 포유동물형 글리코실화 |
MX2009013325A (es) * | 2007-06-07 | 2010-05-20 | Ca Minister Agriculture & Food | Transfeccion y transduccion de plantas con base en nano acarreadores. |
EP2789686A1 (de) | 2013-04-11 | 2014-10-15 | Greenovation Biotech GmbH | Expression von phosphorylierten Glycoproteinen in Pflanzen |
JP6934666B2 (ja) * | 2018-01-18 | 2021-09-15 | 国立研究開発法人産業技術総合研究所 | 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法 |
EP3871687A1 (de) | 2020-02-27 | 2021-09-01 | eleva GmbH | Enzymersatztherapie zur behandlung der pompe-krankheit |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001507563A (ja) * | 1995-11-23 | 2001-06-12 | キャンサー リサーチ キャンペーン テクノロジー リミテッド | Brca2癌感受性遺伝子の同定及び配列決定に関する材料及び方法並びにそれらの使用 |
AU1808699A (en) * | 1997-12-08 | 1999-06-28 | Board Of Trustees Of The University Of Arkansas, The | Purified beta1,2-xylosyltransferase and uses thereof |
DE19754622A1 (de) † | 1997-12-09 | 1999-06-10 | Antje Von Dr Schaewen | Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität |
JP2003520012A (ja) * | 1997-12-19 | 2003-07-02 | ファルマシア・アンド・アップジョン・カンパニー | ヒトSel−10ポリペプチドおよびそれをコードするポリヌクレオチド |
US6207811B1 (en) * | 1998-03-18 | 2001-03-27 | Karl Tryggvason | Nephrin gene and protein |
CA2339409A1 (en) * | 1998-08-11 | 2000-02-24 | Darwin Discovery Ltd. | Identification of the gene causing the mouse scurfy phenotype and its human ortholog |
EP1033405A3 (de) * | 1999-02-25 | 2001-08-01 | Ceres Incorporated | DNS-fragmente mit bestimmter Sequenz und die dadurch kodierte Polypeptide |
AU1573601A (en) * | 1999-10-21 | 2001-04-30 | Monsanto Company | Post-translational modification of recombinant proteins produced in plants |
-
2000
- 2000-03-03 AT AT0035500A patent/AT409381B/de not_active IP Right Cessation
-
2001
- 2001-03-02 WO PCT/EP2001/002352 patent/WO2001064901A1/en active IP Right Grant
- 2001-03-02 AT AT01919367T patent/ATE312931T1/de active
- 2001-03-02 DE DE60115863.6T patent/DE60115863T3/de not_active Expired - Lifetime
- 2001-03-02 KR KR1020027011341A patent/KR100861437B1/ko not_active Expired - Lifetime
- 2001-03-02 ES ES05108014.1T patent/ES2460672T3/es not_active Expired - Lifetime
- 2001-03-02 DK DK05108014.1T patent/DK1621633T3/da active
- 2001-03-02 EP EP01919367.1A patent/EP1263968B2/de not_active Expired - Lifetime
- 2001-03-02 KR KR1020077011024A patent/KR100859919B1/ko not_active Expired - Lifetime
- 2001-03-02 KR KR1020097019435A patent/KR20090101981A/ko not_active Ceased
- 2001-03-02 ES ES01919367.1T patent/ES2252208T5/es not_active Expired - Lifetime
- 2001-03-02 JP JP2001563590A patent/JP5279976B2/ja not_active Expired - Lifetime
- 2001-03-02 CA CA2402015A patent/CA2402015C/en not_active Expired - Lifetime
- 2001-03-02 US US10/220,467 patent/US7205137B2/en not_active Expired - Lifetime
- 2001-03-02 PT PT51080141T patent/PT1621633E/pt unknown
- 2001-03-02 KR KR1020107023909A patent/KR101185123B1/ko not_active Expired - Lifetime
- 2001-03-02 AU AU46495/01A patent/AU781010B2/en not_active Expired
- 2001-03-02 EP EP05108014.1A patent/EP1621633B1/de not_active Expired - Lifetime
- 2001-03-02 KR KR1020087019207A patent/KR20080077296A/ko not_active Ceased
- 2001-03-02 DK DK01919367.1T patent/DK1263968T4/da active
-
2007
- 2007-03-12 US US11/684,898 patent/US20070186311A1/en not_active Abandoned
-
2012
- 2012-03-23 US US13/428,777 patent/US20120331578A1/en not_active Abandoned
-
2013
- 2013-01-16 JP JP2013005404A patent/JP2013116113A/ja active Pending
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent |