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DK1621633T3 - Glycoproteiner produceret i planter med undertrykt ekspression af beta 1,2-xylosyltransferase - Google Patents

Glycoproteiner produceret i planter med undertrykt ekspression af beta 1,2-xylosyltransferase

Info

Publication number
DK1621633T3
DK1621633T3 DK05108014.1T DK05108014T DK1621633T3 DK 1621633 T3 DK1621633 T3 DK 1621633T3 DK 05108014 T DK05108014 T DK 05108014T DK 1621633 T3 DK1621633 T3 DK 1621633T3
Authority
DK
Denmark
Prior art keywords
plants
xylosyltransferase
beta
glycoproteins produced
suppressed expression
Prior art date
Application number
DK05108014.1T
Other languages
English (en)
Inventor
Josef Glössl
Herta Steinkellner
Iain B Wilson
Lukas Mach
Jan Mucha
Richard Strasser
Friedrich Altmann
Original Assignee
Josef Glössl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3672559&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1621633(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Josef Glössl filed Critical Josef Glössl
Application granted granted Critical
Publication of DK1621633T3 publication Critical patent/DK1621633T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/005—Glycopeptides, glycoproteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1077—Pentosyltransferases (2.4.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y204/00—Glycosyltransferases (2.4)
    • C12Y204/02—Pentosyltransferases (2.4.2)
    • C12Y204/02038—Glycoprotein 2-beta-D-xylosyltransferase (2.4.2.38)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01024—Alpha-mannosidase (3.2.1.24)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/0105—Alpha-N-acetylglucosaminidase (3.2.1.50)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01052—Beta-N-acetylhexosaminidase (3.2.1.52)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
DK05108014.1T 2000-03-03 2001-03-02 Glycoproteiner produceret i planter med undertrykt ekspression af beta 1,2-xylosyltransferase DK1621633T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0035500A AT409381B (de) 2000-03-03 2000-03-03 Xylosyltransferase-gen
EP01919367.1A EP1263968B2 (en) 2000-03-03 2001-03-02 Beta 1, 2-xylosyltransferase-gene from arabidopsis

Publications (1)

Publication Number Publication Date
DK1621633T3 true DK1621633T3 (da) 2014-05-19

Family

ID=3672559

Family Applications (2)

Application Number Title Priority Date Filing Date
DK05108014.1T DK1621633T3 (da) 2000-03-03 2001-03-02 Glycoproteiner produceret i planter med undertrykt ekspression af beta 1,2-xylosyltransferase
DK01919367.1T DK1263968T4 (da) 2000-03-03 2001-03-02 Beta 1,2-xylosyltransferasegen fra arabidopsis

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK01919367.1T DK1263968T4 (da) 2000-03-03 2001-03-02 Beta 1,2-xylosyltransferasegen fra arabidopsis

Country Status (12)

Country Link
US (3) US7205137B2 (da)
EP (2) EP1263968B2 (da)
JP (2) JP5279976B2 (da)
KR (5) KR100861437B1 (da)
AT (2) AT409381B (da)
AU (1) AU781010B2 (da)
CA (1) CA2402015C (da)
DE (1) DE60115863T3 (da)
DK (2) DK1621633T3 (da)
ES (2) ES2460672T3 (da)
PT (1) PT1621633E (da)
WO (1) WO2001064901A1 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA01005778A (es) 1998-12-09 2003-07-21 Dow Chemical Co Un metodo para fabricar glicoproteinas que tienen glicosilacion de tipo humano.
PT1772518E (pt) 1999-10-26 2010-10-28 Stichting Dienst Landbouwkundi Glicosilação do tipo mamífero em plantas
ZA200306406B (en) 2001-01-19 2004-09-06 Dow Chemical Co Method for secretory production of glycoprotein having human-type sugar chain using plant cell.
KR101060361B1 (ko) 2002-03-19 2011-08-29 스티칭 디엔스트 랜드보위쿤디그 온데조에크 식물에서 글리칸 프로세싱의 최적화
NZ534881A (en) 2002-03-19 2006-09-29 Plant Res Internat B Mammalian GnTIII expression in plants
AR042145A1 (es) 2002-11-27 2005-06-08 Dow Agrociences Llc Produccion de inmunoglobulinas en plantas con una fucocilacion reducida
EP1510584B1 (en) 2003-08-11 2009-03-18 Greenovation Biotech GmbH Expression promoting sequences from mosses and their uses
NZ598048A (en) 2006-01-17 2013-05-31 Synthon Biopharmaceuticals Bv Compositions and methods for humanization and optimization of n-glycans in plants
US20090060921A1 (en) * 2006-01-17 2009-03-05 Biolex Therapeutics, Inc. Glycan-optimized anti-cd20 antibodies
US20100287657A1 (en) * 2006-03-23 2010-11-11 Bayer Bioscience N.V. Novel Nucleotide Sequences Encoding Nicotiana Beta-1,2-Xylosyltransferase
KR101460953B1 (ko) 2007-04-17 2014-11-13 스티칭 디엔스트 랜드보위쿤디그 온데조에크 비-포유동물 글리코실트랜스퍼라제의 발현에 의한 식물에서의 포유동물형 글리코실화
MX2009013325A (es) * 2007-06-07 2010-05-20 Ca Minister Agriculture & Food Transfeccion y transduccion de plantas con base en nano acarreadores.
EP2789686A1 (en) 2013-04-11 2014-10-15 Greenovation Biotech GmbH Expression of phosphorylated glycoproteins in plants
JP6934666B2 (ja) * 2018-01-18 2021-09-15 国立研究開発法人産業技術総合研究所 植物細胞においてキシロース修飾タンパク質を製造する方法、コアオリゴ糖修飾タンパク質を製造する方法、及びプロテオグリカンを製造する方法
EP3871687A1 (en) 2020-02-27 2021-09-01 eleva GmbH Enzyme replacement therapy for treating pompe disease

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001507563A (ja) * 1995-11-23 2001-06-12 キャンサー リサーチ キャンペーン テクノロジー リミテッド Ｂｒｃａ２癌感受性遺伝子の同定及び配列決定に関する材料及び方法並びにそれらの使用
AU1808699A (en) * 1997-12-08 1999-06-28 Board Of Trustees Of The University Of Arkansas, The Purified beta1,2-xylosyltransferase and uses thereof
DE19754622A1 (de) † 1997-12-09 1999-06-10 Antje Von Dr Schaewen Pflanzliche GntI-Sequenzen und Verwendung derselben zur Gewinnung von Pflanzen mit verminderter oder fehlender N-Acetylglucosaminyltransferase I (GnTI)-Aktivität
JP2003520012A (ja) * 1997-12-19 2003-07-02 ファルマシア・アンド・アップジョン・カンパニー ヒトＳｅｌ−１０ポリペプチドおよびそれをコードするポリヌクレオチド
US6207811B1 (en) * 1998-03-18 2001-03-27 Karl Tryggvason Nephrin gene and protein
CA2339409A1 (en) * 1998-08-11 2000-02-24 Darwin Discovery Ltd. Identification of the gene causing the mouse scurfy phenotype and its human ortholog
EP1033405A3 (en) * 1999-02-25 2001-08-01 Ceres Incorporated Sequence-determined DNA fragments and corresponding polypeptides encoded thereby
AU1573601A (en) * 1999-10-21 2001-04-30 Monsanto Company Post-translational modification of recombinant proteins produced in plants

Also Published As

Publication number Publication date
EP1621633A2 (en) 2006-02-01
AU4649501A (en) 2001-09-12
ES2252208T3 (es) 2006-05-16
US20040121325A1 (en) 2004-06-24
ES2460672T3 (es) 2014-05-14
AU781010B2 (en) 2005-04-28
US20070186311A1 (en) 2007-08-09
JP2013116113A (ja) 2013-06-13
DE60115863D1 (de) 2006-01-19
CA2402015A1 (en) 2001-09-07
ATE312931T1 (de) 2005-12-15
AT409381B (de) 2002-07-25
DE60115863T2 (de) 2006-08-10
KR20070058018A (ko) 2007-06-07
PT1621633E (pt) 2014-07-18
KR20090101981A (ko) 2009-09-29
KR20100119005A (ko) 2010-11-08
KR101185123B1 (ko) 2012-09-21
KR20030030987A (ko) 2003-04-18
JP5279976B2 (ja) 2013-09-04
CA2402015C (en) 2012-07-17
EP1263968B2 (en) 2014-09-10
EP1263968B1 (en) 2005-12-14
ATA3552000A (de) 2001-12-15
EP1621633B1 (en) 2014-04-16
EP1621633A3 (en) 2006-02-08
US7205137B2 (en) 2007-04-17
KR20080077296A (ko) 2008-08-21
DE60115863T3 (de) 2015-01-22
KR100859919B1 (ko) 2008-09-23
ES2252208T5 (es) 2014-11-04
DK1263968T4 (da) 2014-11-03
JP2004500096A (ja) 2004-01-08
US20120331578A1 (en) 2012-12-27
EP1263968A1 (en) 2002-12-11
WO2001064901A1 (en) 2001-09-07
DK1263968T3 (da) 2006-05-01
KR100861437B1 (ko) 2008-10-02

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