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DE60025833D1 - Synthetische melanine auf pflanzenbasis, verfahren zu deren herstellung sowie diese enthaltende zusammensetzungen - Google Patents

Synthetische melanine auf pflanzenbasis, verfahren zu deren herstellung sowie diese enthaltende zusammensetzungen

Info

Publication number
DE60025833D1
DE60025833D1 DE60025833T DE60025833T DE60025833D1 DE 60025833 D1 DE60025833 D1 DE 60025833D1 DE 60025833 T DE60025833 T DE 60025833T DE 60025833 T DE60025833 T DE 60025833T DE 60025833 D1 DE60025833 D1 DE 60025833D1
Authority
DE
Germany
Prior art keywords
production
melanine
compositions containing
based synthetic
plant based
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60025833T
Other languages
English (en)
Inventor
Carlo Ghisalberti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of DE60025833D1 publication Critical patent/DE60025833D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
    • A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/602—Glycosides, e.g. rutin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9728—Fungi, e.g. yeasts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783—Angiosperms [Magnoliophyta]
    • A61K8/9789—Magnoliopsida [dicotyledons]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/02—Preparations containing skin colorants, e.g. pigments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/04—Preparations for care of the skin for chemically tanning the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/10—Preparations for permanently dyeing the hair
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B61/00—Dyes of natural origin prepared from natural sources, e.g. vegetable sources
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
    • C09B69/00—Dyes not provided for by a single group of this subclass
    • C09B69/10—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
    • C09B69/104—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing an indole dye, including melanine derivates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/42—Colour properties
    • A61K2800/43—Pigments; Dyes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polyethers (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60025833T 1999-09-09 2000-09-08 Synthetische melanine auf pflanzenbasis, verfahren zu deren herstellung sowie diese enthaltende zusammensetzungen Expired - Lifetime DE60025833D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1999MI001896A ITMI991896A1 (it) 1999-09-09 1999-09-09 Melanine e pigmenti vegetali
PCT/IB2000/001276 WO2001018125A1 (en) 1999-09-09 2000-09-08 Synthetic vegetal melanins, process for their production and compositions containing thereof

Publications (1)

Publication Number Publication Date
DE60025833D1 true DE60025833D1 (de) 2006-04-13

Family

ID=11383593

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60025833T Expired - Lifetime DE60025833D1 (de) 1999-09-09 2000-09-08 Synthetische melanine auf pflanzenbasis, verfahren zu deren herstellung sowie diese enthaltende zusammensetzungen

Country Status (9)

Country Link
EP (1) EP1212376B1 (de)
JP (1) JP2003509529A (de)
AT (1) ATE316989T1 (de)
AU (1) AU6720200A (de)
BR (1) BR0014257A (de)
CA (1) CA2383932A1 (de)
DE (1) DE60025833D1 (de)
IT (1) ITMI991896A1 (de)
WO (1) WO2001018125A1 (de)

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ES2281425T3 (es) * 2000-07-21 2007-10-01 Croda Chemicals International Limited Uso de una alomelanina para el tratamiento de la inflamacion o irritacion provocada por dha y/o un tensioactivo.
GR20020100011A (el) * 2002-01-16 2003-09-24 Νικολαος Αβραμιδης Η μελανινη για χρηση στην προληψη ή θεραπεια καθε τυπου υπερχοληστερολαιμιας, υπερλιπιδαιμιας και καθε διαταραχη λιπιδιων, σε ανθρωπους και ζωα
EP1492856A4 (de) 2002-04-05 2010-11-10 Univ Massachusetts Lowell Polymere antioxidantien
US7595074B2 (en) 2002-04-05 2009-09-29 University Of Massachusetts Lowell Polymeric antioxidants
WO2004080380A2 (fr) * 2003-03-05 2004-09-23 L'oreal Utilisation de polyphenols catechniques pour la preparation de compositions destinees a favoriser la pigmentation naturelle de la peau
FR2851916B1 (fr) * 2003-03-05 2007-04-27 Utilisation de polyphenols catechiques pour la preparation de compositions destinees a favoriser la pigmentation naturelles de la peau
EP1846460A2 (de) 2004-01-21 2007-10-24 University Of Massachusetts Lowell Nachkupplungssyntheseroute für polymere antioxidantien
FR2873025B1 (fr) * 2004-07-13 2008-02-29 Oreal Procede de traitement cosmetique pour moduler la pigmentation de la peau ou des phaneres
WO2006014605A2 (en) 2004-07-23 2006-02-09 Polnox Corporation Anti-oxidant macromonomers and polymers and methods of making and using the same
JP4659407B2 (ja) * 2004-07-29 2011-03-30 サントリーホールディングス株式会社 オリゴメリックプロアントシアニジン（ｏｐｃ）の分析方法
JP2006076946A (ja) * 2004-09-10 2006-03-23 Hoyu Co Ltd 重金属及び／又は放射性物質の排泄、又は除去を用途とするメラニン類含有組成物、及びメラニン類の用途
WO2006060801A2 (en) 2004-12-03 2006-06-08 Polnox Corporation Process for the synthesis of polyalkylphenol antioxidants
WO2006060800A1 (en) 2004-12-03 2006-06-08 Polnox Corporation Synthesis of aniline and phenol-based antioxidant macromonomers and corresponding polymers
FR2881953A1 (fr) 2005-02-11 2006-08-18 Greenpharma Sa Sa Utilisation de derives de la taxifoline comme agents pigmentants et protecteurs de la peau ou des cheveux
WO2006091705A2 (en) 2005-02-22 2006-08-31 Polnox Corporation Nitrogen and hindered phenol containing dual functional macromolecular antioxidants: synthesis , performances and applications
US7705185B2 (en) 2005-03-25 2010-04-27 Polnox Corporation Alkylated and polymeric macromolecular antioxidants and methods of making and using the same
WO2006116532A2 (en) * 2005-04-28 2006-11-02 University Of Massachusetts Lowell Synthesis of oligo/poly(catechins) and methods of use
WO2007050991A1 (en) 2005-10-27 2007-05-03 Polnox Corporation Stabilized polyolefin compositions
US7705176B2 (en) 2005-10-27 2010-04-27 Polnox Corporation Macromolecular antioxidants based on sterically hindered phenols and phosphites
WO2007064843A1 (en) 2005-12-02 2007-06-07 Polnox Corporation Lubricant oil compositions
GB2433439A (en) * 2005-12-21 2007-06-27 Ciba Sc Holding Ag Use of transmission dyes to protect human skin from UV radiation
WO2008005358A2 (en) 2006-07-06 2008-01-10 Polnox Corporation Novel macromolecular antioxidants comprising differing antioxidant moieties: structures, methods of making and using the same
US7767853B2 (en) 2006-10-20 2010-08-03 Polnox Corporation Antioxidants and methods of making and using the same
JP5201662B2 (ja) * 2007-02-28 2013-06-05 キッコーマン株式会社 血流改善組成物
FR2914859B1 (fr) * 2007-04-13 2012-09-07 Lucas Meyer Cosmetics Compositions cosmetiques stables.
WO2010012751A2 (en) * 2008-07-28 2010-02-04 Omnica Gmbh Sesame seed derived pigments
FR2944794B1 (fr) * 2009-04-28 2012-06-29 Rocher Yves Biolog Vegetale Procede de preparation d'oligomeres de glycoside de flavonoide et utilisation en cosmetique.
WO2011049406A2 (ko) * 2009-10-23 2011-04-28 서울대학교산학협력단 나노 크기의 멜라닌 입자 및 이의 제조방법
WO2012158717A2 (en) * 2011-05-16 2012-11-22 Advanced Hydro Inc Improved membranes with polydopamine coatings
CN103304801A (zh) * 2012-03-14 2013-09-18 云南天士力帝泊洱生物茶集团有限公司 一种茶褐素的制备方法
KR101729710B1 (ko) 2012-04-09 2017-04-24 서울대학교산학협력단 물에 안정하게 분산되는 멜라닌 나노입자를 포함하는 핵자기 공명 영상 조영제
WO2015077635A2 (en) 2013-11-22 2015-05-28 Polnox Corporation Macromolecular antioxidants based on dual type moiety per molecule: structures methods of making and using the same
JP6411733B2 (ja) * 2013-12-09 2018-10-24 株式会社ピュール 噴霧容器入りヘアカラーリング剤
US20160310399A1 (en) * 2013-12-20 2016-10-27 Conopco, Inc., D/B/A Unilever Sunless tanning
WO2017195841A1 (ja) * 2016-05-13 2017-11-16 株式会社Ｎｉｌ 毛髪色素増強剤
JP6562469B2 (ja) * 2016-05-13 2019-08-21 株式会社Ｎｉｌ 毛髪色素増強剤
JP6716130B2 (ja) * 2016-07-04 2020-07-01 学校法人中部大学 抗アレルギー剤
WO2018160879A2 (en) 2017-03-01 2018-09-07 Polnox Corporation Macromolecular corrosion (mcin) inhibitors: structures, methods of making and using the same
CN109260071B (zh) * 2018-09-17 2021-06-15 西安理工大学 一种全天然酶发酵黑色染发剂的制备方法
CN111529434B (zh) * 2020-05-11 2021-09-03 山东农业大学 一种含egcg的唇部预防保健产品及其应用
CN116829544A (zh) * 2020-12-10 2023-09-29 新加坡国立大学 类黄酮二聚物和低聚物的合成方法及其用途
CN113081884B (zh) * 2021-04-26 2022-05-24 北京中医药大学 一种抗黑色素组合物、制备方法及应用
CN113576972B (zh) * 2021-08-11 2023-05-26 昆明医科大学 一种以滇橄榄鲜果果肉为主原料的美白淡斑复方制剂及其制备方法
CN115058005B (zh) * 2022-05-11 2023-06-13 四川大学 低介电损耗的黑色素纳米材料及在基板上制备其涂层的方法及产品
KR102551315B1 (ko) * 2022-08-02 2023-07-04 주식회사 미피션 하이드록시티로솔을 포함하는 모발 염색용 조성물

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FR2704554B1 (fr) * 1993-04-27 1995-07-13 Oreal Procede de preparation d'un pigment melanique de faible granulometrie et son utilisation en cosmetique.
US5744125A (en) * 1993-08-19 1998-04-28 Yale University Cosmetic melanins
US6242415B1 (en) * 1997-02-12 2001-06-05 Sri International Mediation of cytokines by melanin
DE19717837C2 (de) * 1997-04-26 1999-10-28 Thomas Feuerstein HPLC-Säule zur Untersuchung der Melaninaffinität von Substanzen

Also Published As

Publication number Publication date
WO2001018125A1 (en) 2001-03-15
ITMI991896A0 (it) 1999-09-09
EP1212376A1 (de) 2002-06-12
ATE316989T1 (de) 2006-02-15
EP1212376B1 (de) 2006-02-01
BR0014257A (pt) 2002-05-21
JP2003509529A (ja) 2003-03-11
ITMI991896A1 (it) 2001-03-09
AU6720200A (en) 2001-04-10
CA2383932A1 (en) 2001-03-15

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