[go: up one dir, main page]

CS246088B2 - Method of benzamidine derivatives production with bactericidal efficiency - Google Patents

Method of benzamidine derivatives production with bactericidal efficiency Download PDF

Info

Publication number
CS246088B2
CS246088B2 CS845841A CS584184A CS246088B2 CS 246088 B2 CS246088 B2 CS 246088B2 CS 845841 A CS845841 A CS 845841A CS 584184 A CS584184 A CS 584184A CS 246088 B2 CS246088 B2 CS 246088B2
Authority
CS
Czechoslovakia
Prior art keywords
formula
compound
water
ether
ppm
Prior art date
Application number
CS845841A
Other languages
Czech (cs)
English (en)
Other versions
CS584184A2 (en
Inventor
Madeleine Mosse
Henri Demarne
Robert Filhol
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of CS584184A2 publication Critical patent/CS584184A2/cs
Publication of CS246088B2 publication Critical patent/CS246088B2/cs

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C257/00Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines
    • C07C257/10Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines
    • C07C257/18Compounds containing carboxyl groups, the doubly-bound oxygen atom of a carboxyl group being replaced by a doubly-bound nitrogen atom, this nitrogen atom not being further bound to an oxygen atom, e.g. imino-ethers, amidines with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. amidines having carbon atoms of amidino groups bound to carbon atoms of six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/13Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
    • C07C205/19Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups having nitro groups bound to carbon atoms of six-membered aromatic rings and hydroxy groups bound to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/18Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part
    • C07C33/20Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part monocyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CS845841A 1983-08-03 1984-07-30 Method of benzamidine derivatives production with bactericidal efficiency CS246088B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8312824A FR2550192B1 (fr) 1983-08-03 1983-08-03 Nouveaux derives de la benzamidine a activite antimicrobienne, leur procede de preparation, leur utilisation en tant que medicaments desinfectants ou conservateurs

Publications (2)

Publication Number Publication Date
CS584184A2 CS584184A2 (en) 1985-12-16
CS246088B2 true CS246088B2 (en) 1986-10-16

Family

ID=9291379

Family Applications (1)

Application Number Title Priority Date Filing Date
CS845841A CS246088B2 (en) 1983-08-03 1984-07-30 Method of benzamidine derivatives production with bactericidal efficiency

Country Status (25)

Country Link
US (1) US4720581A (sv)
EP (1) EP0136195B1 (sv)
JP (1) JPS6054351A (sv)
KR (1) KR920000373B1 (sv)
AR (1) AR242556A1 (sv)
AT (1) ATE27952T1 (sv)
AU (1) AU563648B2 (sv)
CA (1) CA1238922A (sv)
CS (1) CS246088B2 (sv)
DD (1) DD220025A5 (sv)
DE (1) DE3464362D1 (sv)
DK (1) DK158662C (sv)
ES (1) ES8504112A1 (sv)
FI (1) FI77020C (sv)
FR (1) FR2550192B1 (sv)
GR (1) GR82449B (sv)
HU (1) HU192567B (sv)
IL (1) IL72480A (sv)
MA (1) MA20180A1 (sv)
NO (1) NO157618C (sv)
NZ (1) NZ209092A (sv)
PT (1) PT79003B (sv)
SU (1) SU1319784A3 (sv)
YU (1) YU127684A (sv)
ZA (1) ZA845682B (sv)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2504361Y2 (ja) * 1990-12-14 1996-07-10 大和ハウス工業株式会社 建物の配管固定構造
DE4447361A1 (de) * 1994-12-21 1996-06-27 Schuelke & Mayr Gmbh Biozide Alkohole, ihre Herstellung und ihre Verwendung
EP1602646A4 (en) * 2003-02-19 2010-07-28 Eisai R&D Man Co Ltd PROCESS FOR PREPARING CYCLIC BENZAMIDINE DERIVATIVES
CA2572894C (en) * 2004-07-05 2010-06-29 Dong Wha Pharmaceutical Ind. Co., Ltd. An improved process for preparing n-hydroxy-4-{5-[4-(5-isopropyl-2-methyl-1,3-thiazol-4-yl)-phenoxy]-pentoxy}-benzamidine
CN111362834B (zh) * 2020-02-26 2021-04-02 湖南大学 一种具有抗耐药性的抗菌脒类低聚物及其制作方法和用途
CN114773250A (zh) * 2021-08-02 2022-07-22 湖南大学 具有抗耐药性的抗菌脒类低聚物及其制作方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2934438A (en) * 1958-03-20 1960-04-26 Michener Harold David Preservation process with alkyl guanidines
US3769427A (en) * 1970-10-01 1973-10-30 Armour Pharma Pharmaceutical compositions and methods of using same
IT1153988B (it) * 1981-10-05 1987-01-21 Medea Res Srl Composizioni ad attivita' antimicrobica

Also Published As

Publication number Publication date
AU563648B2 (en) 1987-07-16
ZA845682B (en) 1985-02-27
ES534828A0 (es) 1985-04-16
DK362384D0 (da) 1984-07-24
US4720581A (en) 1988-01-19
FI77020C (sv) 1989-01-10
NO843114L (no) 1985-02-04
KR920000373B1 (ko) 1992-01-13
FR2550192A1 (fr) 1985-02-08
DK362384A (da) 1985-02-04
ATE27952T1 (de) 1987-07-15
EP0136195B1 (fr) 1987-06-24
ES8504112A1 (es) 1985-04-16
CA1238922A (en) 1988-07-05
FR2550192B1 (fr) 1986-04-04
IL72480A0 (en) 1984-11-30
KR850001730A (ko) 1985-04-01
PT79003B (fr) 1986-06-18
GR82449B (sv) 1984-12-13
IL72480A (en) 1987-10-30
AR242556A1 (es) 1993-04-30
DK158662B (da) 1990-07-02
PT79003A (fr) 1984-08-01
NO157618C (no) 1988-04-20
MA20180A1 (fr) 1985-04-01
FI77020B (fi) 1988-09-30
FI843061A0 (fi) 1984-08-02
DK158662C (da) 1990-12-10
DD220025A5 (de) 1985-03-20
FI843061A (fi) 1985-02-04
NO157618B (no) 1988-01-11
NZ209092A (en) 1987-03-06
EP0136195A1 (fr) 1985-04-03
CS584184A2 (en) 1985-12-16
HU192567B (en) 1987-06-29
DE3464362D1 (en) 1987-07-30
AU3079084A (en) 1985-02-07
SU1319784A3 (ru) 1987-06-23
JPS6054351A (ja) 1985-03-28
HUT34724A (en) 1985-04-28
YU127684A (en) 1986-12-31

Similar Documents

Publication Publication Date Title
JP2001509137A (ja) 皮膚疾患の治療方法
JP2907640B2 (ja) 尋常性ざ瘡用皮膚外用剤
EP0288352B1 (fr) Dérivés aromatiques, leur préparation et leur utilisation comme antimicrobiens
FI82237C (sv) Förfarande för framställning av antimikrobiella bensoesyraderivat
US4196217A (en) Hydroxylated amines with bacteriostatic activity
CS246088B2 (en) Method of benzamidine derivatives production with bactericidal efficiency
US5910513A (en) Substituted benzyl derivatives of polyalkylene polyamines and their use in cosmetic and pharmaceutical compositions
US4820717A (en) Antimicrobial aromatic derivatives substituted by an (omega amino) alkanol group and compositions containing them
US8729312B2 (en) Derivatives of novel peroxides, method of preparation thereof and use thereof in human medicine as well as in cosmetics for the treatment or prevention of acne
US4539206A (en) Topical compositions containing copper (II) complexes of 3,5-dioxo-pyrazolidine derivatives and methods of combatting inflammation with them
JPH0930920A (ja) 尋常性ざ瘡用皮膚外用剤