CO4410193A1 - Heteroaril-oxazolidinonas de 5 eslabones - Google Patents
Heteroaril-oxazolidinonas de 5 eslabonesInfo
- Publication number
- CO4410193A1 CO4410193A1 CO95031767A CO95031767A CO4410193A1 CO 4410193 A1 CO4410193 A1 CO 4410193A1 CO 95031767 A CO95031767 A CO 95031767A CO 95031767 A CO95031767 A CO 95031767A CO 4410193 A1 CO4410193 A1 CO 4410193A1
- Authority
- CO
- Colombia
- Prior art keywords
- carbon
- atoms
- branched
- linear
- different
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/48—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing alicyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
REIVINDICACION HETEROARIL-OXAZOLIDINONAS, DE FORMULA GENERAL(I) FIGURA NO. 1 EN LA CUAL R1 REPRESENTA AZIDO, HIDROXILO O UN GRUPO DE FOR- MULA -OR2, -O-SO(SUBIND)2R3 o -NR4R5 EN DONDE R2 SIGNIFICA ACILO, LINEAL O RAMIFICADO, CON HAS- TA 8 ATOMOS DE CARBONO O UN GRUPO PROTECTOR HIDRO- XILO, R3 SIGNIFICA ALQUILO, LINEAL O RAMIFICADO, CON HASTA 4 ATOMOS DE CARBONO O FENILO QUE, DADO EL CASO, ESTA SUSTITUIDO POR ALQUILO, LINEAL O RAMI- FICADO, CON HASTA 4 ATOMOS DE CARBONO, R4 Y R5 SON IGUALES O DISTINTOS Y SIGNIFICAN DICLOALQUILO CON 3 A 6 ATOMOS DE CARBO- NO, HIDROGENO, FENILO O ALQUILO, LINEAL O RAMIFI- CADO, CON HASTA 8 ATOMOS DE CARBONO O UN GRUPO PROTECTOR DE AMINO, O R4 o R5 SIGNIFICAN UN GRUPO DE FORMULA -CO-R6, EN DONDE R6 SIGNIFICA CICLOALQUILO CON 3 A 6 ATOMOS DE CAR- BONO, ALQUILO, LINEAL O RAMIFICADO, CON HASTA 8 A- TOMOS DE CARBONO, FENILO O HIDROGENO, A REPRESENTA UN HETEROCICLO AROMATICO DE 5 ESLA- BONES, UNIDO DIRECTAMENTE SOBRE EL ATOMO DE CARBO- NO, CON HASTA 3 HETEROATOMOS DEL GRUPO S, N y/u O QUE, ADICIONALMENTE PUEDE POSEER UN ANILLO DE BEN- CENO O NAFTALENO CONDENSADO, DONDE LOS CICLOS, DA- DO EL CASO, ESTAN HASTA TRISUSTITUIDOS RESPECTIVA- MENTE, POR SUSTITUYENTES IGUALES O DISTINTOS, CAR- BOXI, HALOGENO, CIANO, MERCAPTO, FORMILO, TRIFLU- ORMETILO, NITRO, ALCOXI, ALCOXICARBONILO, ALQUIL- TIO O ACILO, O RAMIFICADO, CON HASTA 6 ATOMOS DE CARBONO RESPECTIVAMENTE O POR ALQUILO LINEAL O RA- MIFICADO CON HASTA 6 ATOMOS DE CARBONO QUE, POR SU PARTE, PUEDE ESTAR SUSTITUIDO POR HIDROXILO, ALCO- XI O ACILO, LINEAL O RAMIFICADO, CON HASTA 5 ATO- MOS DE CARBONO O POR UN GRUPO DE FORMULA -NR7R4, EN DONDE R7 y R8 SON IGUALES O DISTINTOS Y SIGNIFICAN HIDROGENO, ALQUILO, LINEAL O RAMIFICA- DO, CON HASTA 4 ATOMOS DE CARBONO O FENILO, O, JUNTO CON EL ATOMO DE NITROGENO FORMAN UN HETERO- CICLO SATURADO DE 5 A 6 ESLABONES, DADO EL CASO CON OTRO HETEROATOMO DEL GRUPO N, S y/u O QUE, POR SU PARTE, PUEDE ESTAR SUSTITUIDO TAMBIEN, DADO EL CASO, EN OTRO ATOMO DE NITROGENO POR ALQUILO O A- CILO, LINEAL O RAMIFICADO, CON HASTA e ATOMOS DE CARBONO, Y/O LOS CICLOS ESTAN SUSTITUIDOS, DADO EL CASO, POR UN GRUPO DE FORMULA -NR7´R8´, EN DONDE R7´ Y R8´ SON IGUALES O DISTINTOS Y TIENEN EL SIG- NIFICADO INDICADO MAS ARRIBA PARA R7 Y R8 Y SON I- GUALES O DISTINTOS A ESTOS, Y/O LOS CICLOS ESTAN SUSTITUIDOS, DADO EL CASO, POR (C2-C8)-ALQUENILFENILO, FENILO O POR UN HETEROCI- CLO SATURADO O INSATURADO DE 5 o 6 ESLABONES, CON HASTA e HETEROATOMOS DEL GRUPO S, N y/u O, QUE POR SU PARTE ESTAN SUSTITUIDOS, DADO EL CASO, POR UN GRUPO DE FORMULA -CO-NR9R10, NR11R12, NR13-S(O2)- R14, R15R16N-SO2 o R17-S(O)a- EN DONDE a SIGNIFICA UN NUMERO 0, 1 o 2, R9, R10, R13, R15 y R16 SON IGUALES O DISTINTOS Y SIGNIFICAN HIDROGENO, ALQUILO, LINEAL O RAMIFICA- DO, CON HASTA 6 ATOMOS DE CARBONO O FENILO R11 y R12 SON IGUALES O DISTINTOS Y TIENEN EL SIG- NIFICADO INDICADO MAS ARRIBA PARA R7 Y R8 Y SON I- GUALES O DISTINTOS A ESTOS, R14 Y R17 SON IGUALES O DISTINTOS Y TIENEN EL SIG- NIFICADO INDICADO MAS ARRIBA PARA R3 Y SON IGUALES O DISTINTOS A ESTE, Y/O POR SU PARTE, DADO EL CA- SO, ESTAN HASTA BISUSTITUIDOS, POR SUSTITUYENTES IGUALES O DISTINTOS CARBOXI, HALOGENO, CIANO, MER- CAPTO, FORMILO, TRIFLUORMETILO, NITRO, FENILO, AL- COXI, ALCOXICARBONILO, ALQUITIO O ACILO, LINEAL O RAMIFICADO, CON HASTA 6 ATOMOS DE CARBONO RESPEC- TIVAMENTE O POR ALQUILO LINEAL O RAMIFICADO CON HASTA 6 ATOMOS DE CARBONO QUE, POR SU PARTE, PUEDE ESTAR SUSTITUIDO POR HIDROXILO, POR ALCOXI O ACI- LO, LINEAL O RAMIFICADO, CON HASTA 5 ATOMOS DE CARBONO O POR UN GRUPO DE FORMULA -NR18R19, EN DONDE R18 Y R19 TIENEN EL SIGNIFICADO INDICADO MAS ARRI- BA PARA R7 Y R8 Y SON IGUALES O DISTINTOS A ESTOS, Y/O LOS CICLOS ESTAN SUSTITUIDOS, DADO EL CASO, POR UN RESTO DE FORMULA FIGURA 2 EN DONDE n SIGNIFICA UN NUMERO 0, 1 o 2 Y SUS SALES Y S-OXIDOS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4425613A DE4425613A1 (de) | 1994-07-20 | 1994-07-20 | 5-gliedrige Heteroaryl-oxazolidinone |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CO4410193A1 true CO4410193A1 (es) | 1997-01-09 |
Family
ID=6523633
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CO95031767A CO4410193A1 (es) | 1994-07-20 | 1995-07-18 | Heteroaril-oxazolidinonas de 5 eslabones |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US5698574A (es) |
| EP (1) | EP0693491A1 (es) |
| JP (1) | JPH0853443A (es) |
| KR (1) | KR960004343A (es) |
| CN (1) | CN1121919A (es) |
| AU (1) | AU695661B2 (es) |
| BG (1) | BG99791A (es) |
| CA (1) | CA2154026A1 (es) |
| CO (1) | CO4410193A1 (es) |
| CZ (1) | CZ187395A3 (es) |
| DE (1) | DE4425613A1 (es) |
| EE (1) | EE9500044A (es) |
| FI (1) | FI953476L (es) |
| HR (1) | HRP950391A2 (es) |
| HU (1) | HUT74003A (es) |
| IL (1) | IL114622A (es) |
| MA (1) | MA23621A1 (es) |
| NO (1) | NO304488B1 (es) |
| NZ (1) | NZ272596A (es) |
| PE (1) | PE35896A1 (es) |
| PL (1) | PL309685A1 (es) |
| RO (1) | RO115161B1 (es) |
| RU (1) | RU95113086A (es) |
| SK (1) | SK91695A3 (es) |
| SV (1) | SV1995000042A (es) |
| TN (1) | TNSN95083A1 (es) |
| YU (1) | YU49195A (es) |
| ZA (1) | ZA956015B (es) |
Families Citing this family (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4425609A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | Benzofuranyl- und Benzothienyloxazolidinone |
| NZ302844A (en) * | 1995-02-03 | 1999-06-29 | Upjohn Co | Antimicrobial hetero-aromatic ring substituted phenyloxazolidinones |
| US6124334A (en) * | 1995-02-03 | 2000-09-26 | Pharmacia & Upjohn Company | Hetero-aromatic ring substituted phenyloxazolidinone antimicrobials |
| MX9801578A (es) * | 1995-09-01 | 1998-08-30 | Upjohn Co | Feniloxazolidinonas que tienen un enlace c-c para anillos heterociclicos de 4-8 miembros. |
| DE19601264A1 (de) * | 1996-01-16 | 1997-07-17 | Bayer Ag | Pyrido-annellierte Thienyl- und Furanyl-Oxazolidinone |
| GB9601666D0 (en) * | 1996-01-27 | 1996-03-27 | Zeneca Ltd | Chemical compounds |
| DE19604223A1 (de) * | 1996-02-06 | 1997-08-07 | Bayer Ag | Neue substituierte Oxazolidinone |
| HRP970049A2 (en) | 1996-02-06 | 1998-04-30 | Bayer Ag | New heteroaryl oxazolidinones |
| GB9702213D0 (en) | 1996-02-24 | 1997-03-26 | Zeneca Ltd | Chemical compounds |
| GB9609919D0 (en) | 1996-05-11 | 1996-07-17 | Zeneca Ltd | Chemical compounds |
| ES2186916T3 (es) * | 1996-08-21 | 2003-05-16 | Upjohn Co | Derivados de isoxazolina como agentes antimicrobianos. |
| GB9717804D0 (en) | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
| GB9717807D0 (en) * | 1997-08-22 | 1997-10-29 | Zeneca Ltd | Chemical compounds |
| GB9725244D0 (en) | 1997-11-29 | 1998-01-28 | Zeneca Ltd | Chemical compounds |
| JP2002501059A (ja) | 1998-01-23 | 2002-01-15 | ファルマシア・アンド・アップジョン・カンパニー | オキサゾリジノンの組合せライブラリー、組成物および調製方法 |
| US7002020B1 (en) | 1998-01-23 | 2006-02-21 | Pharmacia & Upjohn Company | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
| US6562844B2 (en) | 1998-01-23 | 2003-05-13 | Pharmacia & Upjohn Company | Oxazolidinone combinatorial libraries, compositions and methods of preparation |
| US6262044B1 (en) * | 1998-03-12 | 2001-07-17 | Novo Nordisk A/S | Modulators of protein tyrosine phosphatases (PTPASES) |
| BR9911779A (pt) * | 1998-05-12 | 2001-02-06 | American Home Prod | Benzotiofenos, benzofuranos e indóis úteis no tratamento de resistência à insulina e hiperglicemia |
| US6232322B1 (en) | 1998-05-12 | 2001-05-15 | American Home Products Corporation | Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
| US6699896B1 (en) | 1998-05-12 | 2004-03-02 | Wyeth | Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia |
| US6221902B1 (en) | 1998-05-12 | 2001-04-24 | American Home Products Corporation | Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia |
| US6451827B2 (en) | 1998-05-12 | 2002-09-17 | Wyeth | 2,3,5-substituted biphenyls useful in the treatment of insulin resistance and hyperglycemia |
| US6110962A (en) * | 1998-05-12 | 2000-08-29 | American Home Products Corporation | 11-aryl-benzo[B]naphtho[2,3-D]furans and 11-aryl-benzo[B]naphtho[2,3-D]thiophenes useful in the treatment of insulin resistance and hyperglycemia |
| US6121271A (en) * | 1998-05-12 | 2000-09-19 | American Home Products Corporation | Naphtho[2,3-B]heteroar-4-yl derivatives |
| US6251936B1 (en) | 1998-05-12 | 2001-06-26 | American Home Products Corporation | Benzothiophenes, benzofurans, and indoles useful in the treatment of insulin resistance and hyperglycemia |
| US6110963A (en) * | 1998-05-12 | 2000-08-29 | American Home Products Corporation | Aryl-oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia |
| JP2002516305A (ja) | 1998-05-12 | 2002-06-04 | アメリカン・ホーム・プロダクツ・コーポレイション | インスリン抵抗性および高血糖症の治療に有用な２，３，５−置換ビフェニル |
| PL345162A1 (en) * | 1998-06-05 | 2001-12-03 | Astrazeneca Ab | Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them |
| MY122454A (en) | 1998-06-05 | 2006-04-29 | Upjohn Co | Use of oxazolidinones for the preparation of a medicament for transdermal delivery |
| AU740781B2 (en) | 1998-07-14 | 2001-11-15 | Pharmacia & Upjohn Company | Oxazolidinones to treat eye infections |
| US6420349B1 (en) | 1998-08-24 | 2002-07-16 | Bristol-Myers Squibb Company | Isoxazolinone antibacterial agents |
| AR020660A1 (es) * | 1998-09-30 | 2002-05-22 | Alcon Lab Inc | Composiciones antibioticas para el tratamiento de ojos, oidos y nariz |
| AU4224699A (en) | 1999-01-27 | 2000-08-18 | Pharmacia & Upjohn Company | Assays for modulators of elongation factor p activity |
| US6310081B1 (en) | 1999-05-10 | 2001-10-30 | American Home Products Corporation | Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia |
| GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| MY127336A (en) | 2000-03-22 | 2006-11-30 | Upjohn Co | Container for linezolid iv solution |
| US6514529B2 (en) | 2000-03-22 | 2003-02-04 | Pharmacia & Upjohn Company | Oxazolidinone tablet formulation |
| GB0009803D0 (en) * | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| US6465456B2 (en) | 2000-06-29 | 2002-10-15 | Bristol-Myers Squibb Company | Isoxazolinone antibacterial agents |
| US6544991B2 (en) | 2000-06-30 | 2003-04-08 | Pharmacia & Upjohn Company | Compositions and methods for treating bacterial infections |
| PE20020300A1 (es) * | 2000-08-22 | 2002-05-10 | Pharmacia Corp | Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco |
| WO2002018354A1 (en) * | 2000-08-31 | 2002-03-07 | Abbott Laboratories | Oxazolidinones and their use as antibacterial agents |
| PE20020578A1 (es) | 2000-10-10 | 2002-08-14 | Upjohn Co | Una composicion de antibiotico topico para el tratamiento de infecciones oculares |
| ES2256331T3 (es) | 2000-12-21 | 2006-07-16 | PHARMACIA & UPJOHN COMPANY LLC | Derivados de quinolina antimicrobianos y uso de los mismos para tratar infecciones bacterianas. |
| GB0118407D0 (en) * | 2001-07-27 | 2001-09-19 | Cipla Ltd | Oxazolidinone derivatives as antibacterial agents |
| JP2003192773A (ja) * | 2001-12-26 | 2003-07-09 | Mitsui Chemicals Inc | 生体吸収性ポリヒドロキシカルボン酸及びその製造法 |
| TW200302095A (en) * | 2002-01-25 | 2003-08-01 | Upjohn Co | Oxazolidinone cotherapy |
| AU2003218059A1 (en) * | 2002-02-22 | 2003-09-09 | Pharmacia Corporation | Ophthalmic antibiotic drug formulations containing a cyclodextrin compound and cetyl pyridinium chloride |
| AR038536A1 (es) * | 2002-02-25 | 2005-01-19 | Upjohn Co | N-aril-2-oxazolidinona-5- carboxamidas y sus derivados |
| US7141588B2 (en) * | 2002-02-25 | 2006-11-28 | Pfizer, Inc. | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives |
| CA2476545A1 (en) * | 2002-03-29 | 2003-10-16 | Pharmacia & Upjohn Company | Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections |
| ATE321760T1 (de) * | 2002-08-12 | 2006-04-15 | Pharmacia & Upjohn Co Llc | N-aryl-2-oxazolidinone und deren derivate |
| WO2004045616A1 (en) * | 2002-11-21 | 2004-06-03 | Pharmacia & Upjohn Company Llc | N-(4-(piperazin-1-yl)-phenyl-2-oxazolidinone-5-carboxamide derivates and related compounds as antibacterial agents |
| US20060116400A1 (en) * | 2002-11-28 | 2006-06-01 | Astrazeneca Ab | Oxazolidinone and/or isoxazoline derivatives as antibacterial agents |
| GB0229526D0 (en) * | 2002-12-19 | 2003-01-22 | Astrazeneca Ab | Chemical compounds |
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| US20040191326A1 (en) * | 2003-03-31 | 2004-09-30 | Reo Joseph P. | Taste-masking vehicle for coated oxazolidinone particles |
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| AU2006231919A1 (en) | 2005-04-06 | 2006-10-12 | Pharmacia & Upjohn Company Llc | 7-fluoro-1,3-dihydro-indol-2-one oxazolidinones as antibacterial agents |
| WO2008021338A2 (en) * | 2006-08-15 | 2008-02-21 | Wyeth | Tricyclic oxazolidone derivatives useful as pr modulators |
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| WO2013182070A1 (zh) * | 2012-06-08 | 2013-12-12 | 四川贝力克生物技术有限责任公司 | 一种用于预防或治疗分支杆菌疾病的药物 |
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| DE3723797A1 (de) * | 1987-07-18 | 1989-01-26 | Merck Patent Gmbh | Oxazolidinone |
| US4921869A (en) * | 1987-10-09 | 1990-05-01 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents |
| US5036092A (en) * | 1987-10-09 | 1991-07-30 | Du Pont Merck Pharmaceutical | Aminomethyl oxooxazolidinyl azacycloalkylbenzene derivatives useful as antibacterial agents |
| US4965268A (en) * | 1987-10-09 | 1990-10-23 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents |
| US4801600A (en) * | 1987-10-09 | 1989-01-31 | E. I. Du Pont De Nemours And Company | Aminomethyl oxooxazolidinyl cycloalkylbenzene derivatives useful as antibacterial agents |
| CA1320730C (en) * | 1987-10-16 | 1993-07-27 | The Du Pont Merck Pharmaceutical Company | Aminomethyl oxooxazolidinyl aroylbenzene derivatives useful as antibacterial agents |
| US5254577A (en) * | 1988-07-29 | 1993-10-19 | The Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
| US4948801A (en) * | 1988-07-29 | 1990-08-14 | E. I. Du Pont De Nemours And Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
| EP0359418B1 (en) * | 1988-09-15 | 1994-10-12 | The Upjohn Company | 5'-Indolinyl-5beta-amidomethyloxazolidin-2-ones, 3-(fused-ring substituted)phenyl-5beta-amidomethyloxazolidin-2-ones and 3-(nitrogen substituted)phenyl-5beta-amidomethyloxazolidin-2-ones |
| DE3902439A1 (de) * | 1989-01-27 | 1990-08-02 | Basf Ag | Pflanzenschuetzende mittel auf basis von 1-aryl- bzw. 1-hetarylimidazolcarbonsaeureestern |
| KR100257418B1 (ko) * | 1991-11-01 | 2000-05-15 | 로렌스 티. 마이젠헬더 | 치환된 아릴-및 헤테로아릴-페닐옥사졸리디논 |
-
1994
- 1994-07-20 DE DE4425613A patent/DE4425613A1/de not_active Withdrawn
-
1995
- 1995-07-07 EP EP95110629A patent/EP0693491A1/de not_active Withdrawn
- 1995-07-10 HR HRP4425613.2A patent/HRP950391A2/hr not_active Application Discontinuation
- 1995-07-11 RO RO95-01295A patent/RO115161B1/ro unknown
- 1995-07-13 AU AU24988/95A patent/AU695661B2/en not_active Ceased
- 1995-07-17 US US08/503,183 patent/US5698574A/en not_active Expired - Fee Related
- 1995-07-17 IL IL11462295A patent/IL114622A/xx active IP Right Grant
- 1995-07-17 CA CA002154026A patent/CA2154026A1/en not_active Abandoned
- 1995-07-18 NZ NZ272596A patent/NZ272596A/en unknown
- 1995-07-18 JP JP7203904A patent/JPH0853443A/ja active Pending
- 1995-07-18 CO CO95031767A patent/CO4410193A1/es unknown
- 1995-07-18 PL PL95309685A patent/PL309685A1/xx unknown
- 1995-07-18 FI FI953476A patent/FI953476L/fi unknown
- 1995-07-18 EE EE9500044A patent/EE9500044A/xx unknown
- 1995-07-18 BG BG99791A patent/BG99791A/bg unknown
- 1995-07-19 CN CN95108995A patent/CN1121919A/zh active Pending
- 1995-07-19 NO NO952866A patent/NO304488B1/no not_active IP Right Cessation
- 1995-07-19 HU HU9502167A patent/HUT74003A/hu unknown
- 1995-07-19 PE PE1995274242A patent/PE35896A1/es not_active Application Discontinuation
- 1995-07-19 CZ CZ951873A patent/CZ187395A3/cs unknown
- 1995-07-19 KR KR1019950021178A patent/KR960004343A/ko not_active Application Discontinuation
- 1995-07-19 YU YU49195A patent/YU49195A/sh unknown
- 1995-07-19 TN TNTNSN95083A patent/TNSN95083A1/fr unknown
- 1995-07-19 MA MA23960A patent/MA23621A1/fr unknown
- 1995-07-19 RU RU95113086/04A patent/RU95113086A/ru unknown
- 1995-07-19 SK SK916-95A patent/SK91695A3/sk unknown
- 1995-07-19 ZA ZA956015A patent/ZA956015B/xx unknown
- 1995-07-20 SV SV1995000042A patent/SV1995000042A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO304488B1 (no) | 1998-12-28 |
| PE35896A1 (es) | 1996-10-14 |
| CZ187395A3 (en) | 1996-02-14 |
| IL114622A (en) | 1999-07-14 |
| CN1121919A (zh) | 1996-05-08 |
| JPH0853443A (ja) | 1996-02-27 |
| AU695661B2 (en) | 1998-08-20 |
| US5698574A (en) | 1997-12-16 |
| MA23621A1 (fr) | 1996-04-01 |
| KR960004343A (ko) | 1996-02-23 |
| NO952866L (no) | 1996-01-22 |
| EP0693491A1 (de) | 1996-01-24 |
| HRP950391A2 (en) | 1997-06-30 |
| RO115161B1 (ro) | 1999-11-30 |
| YU49195A (sh) | 1998-12-23 |
| FI953476A0 (fi) | 1995-07-18 |
| NO952866D0 (no) | 1995-07-19 |
| HU9502167D0 (en) | 1995-09-28 |
| IL114622A0 (en) | 1995-11-27 |
| ZA956015B (en) | 1996-02-22 |
| TNSN95083A1 (fr) | 1996-02-06 |
| CA2154026A1 (en) | 1996-01-21 |
| BG99791A (en) | 1996-04-30 |
| PL309685A1 (en) | 1996-01-22 |
| FI953476L (fi) | 1996-01-21 |
| SV1995000042A (es) | 1996-03-28 |
| HUT74003A (en) | 1996-10-28 |
| DE4425613A1 (de) | 1996-01-25 |
| EE9500044A (et) | 1996-02-15 |
| AU2498895A (en) | 1996-02-01 |
| RU95113086A (ru) | 1997-06-27 |
| SK91695A3 (en) | 1996-02-07 |
| NZ272596A (en) | 1997-03-24 |
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