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BR9706058A - Dna recombinante replicável autonomamente em cédulas de bactérias corineformes, bactéria corineforme, e, processo para produzir l-lisina - Google Patents

Dna recombinante replicável autonomamente em cédulas de bactérias corineformes, bactéria corineforme, e, processo para produzir l-lisina

Info

Publication number
BR9706058A
BR9706058A BR9706058-5A BR9706058A BR9706058A BR 9706058 A BR9706058 A BR 9706058A BR 9706058 A BR9706058 A BR 9706058A BR 9706058 A BR9706058 A BR 9706058A
Authority
BR
Brazil
Prior art keywords
lysine
bacteria
corineform
corineform bacteria
recombinant dna
Prior art date
Application number
BR9706058-5A
Other languages
English (en)
Other versions
BRPI9706058B1 (pt
Inventor
Atsushi Hayakawa
Masakazu Sugimoto
Yasuhiki Yoshihara
Tsuyoshi Nakamatsu
Original Assignee
Ajinomoto Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=18179283&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9706058(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ajinomoto Kk filed Critical Ajinomoto Kk
Publication of BR9706058A publication Critical patent/BR9706058A/pt
Publication of BRPI9706058B1 publication Critical patent/BRPI9706058B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1217—Phosphotransferases with a carboxyl group as acceptor (2.7.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

"DNA RECOMBINANTE REPLICáVEL AUTONOMAMENTE EM CéLULAS DE BACTéRIAS CORINEFORMES, BACTéRIA CORINEFORME, E, PROCESSO PARA PRODUZIR L-LISINA". Um DNA recombinante replicável autonomamente em células de bactéria corineforme, compreendendo uma sequência de DNA codificando para uma aspartoquinase em que a inibição da retro-alimentação por L-lisina e L-treonina é substancialmente dessensibilizada, e uma sequência de DNA codificando para uma descarboxilase diaminopimelato, uma bactéria corineforme abrigando uma aspartoquinase em que a inibição de retro-alimentação por L-lisina e L-treonina é substancialmente dessensibilizada, e compreendendo uma sequência de DNA melhorada codificando para uma descarboxilase diaminopimelato, e um processo para produzir L-lisina compreendendo as etapas de cultivar a bactéria corineforme em um meio apropriado para permitir que a L-lisina seja produzida e acumulada em uma cultura da bactéria, e coletar a L-lisina da cultura.
BRPI9706058A 1996-12-05 1997-12-05 vetor recombinante replicável autonomamente em células de bactérias corineformes, bactéria corineforme, e, processo para produzir l-lisina BRPI9706058B1 (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP32565896A JP4075087B2 (ja) 1996-12-05 1996-12-05 Ｌ−リジンの製造法

Publications (2)

Publication Number Publication Date
BR9706058A true BR9706058A (pt) 1999-10-05
BRPI9706058B1 BRPI9706058B1 (pt) 2015-11-03

Family

ID=18179283

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI9706058A BRPI9706058B1 (pt) 1996-12-05 1997-12-05 vetor recombinante replicável autonomamente em células de bactérias corineformes, bactéria corineforme, e, processo para produzir l-lisina

Country Status (11)

Country Link
US (1) US6221636B1 (pt)
EP (1) EP0857784B1 (pt)
JP (1) JP4075087B2 (pt)
CN (1) CN1161470C (pt)
BR (1) BRPI9706058B1 (pt)
DE (1) DE69736699T2 (pt)
DK (1) DK0857784T3 (pt)
ES (1) ES2273356T3 (pt)
HU (1) HU224409B1 (pt)
PL (1) PL190206B1 (pt)
SK (1) SK285146B6 (pt)

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CN1690191A (zh) 1999-04-09 2005-11-02 味之素株式会社 L－氨基酸生产菌以及用于生产l－氨基酸的方法
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JP2003180355A (ja) * 1999-07-02 2003-07-02 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
CN1298854C (zh) 1999-07-02 2007-02-07 味之素株式会社 编码蔗糖pts酶ⅱ的dna
JP2003169674A (ja) * 1999-07-02 2003-06-17 Ajinomoto Co Inc Ｌ−リジンの製造法
JP2003144161A (ja) * 1999-07-02 2003-05-20 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
TW200734460A (en) 1999-10-04 2007-09-16 Ajinomoto Kk Genes for heat resistant enzymes of amino acid biosynthetic pathway derived from thermophilic coryneform bacteria
US20040121428A1 (en) * 1999-12-24 2004-06-24 Masakazu Sugimoto Process for producing l-amino acid and novel gene
US6927046B1 (en) * 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
BRPI0017148B1 (pt) * 2000-03-09 2016-03-01 Basf Aktiengesellschfat vetor, célula hospedeira recombinante, e, método para produzir um produto químico fino
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KR100838038B1 (ko) * 2006-12-29 2008-06-12 씨제이제일제당 (주) Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용한 ｌ-라이신 생산 방법
KR100838035B1 (ko) * 2006-12-29 2008-06-12 씨제이제일제당 (주) Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용한 ｌ-라이신 생산 방법
KR100830826B1 (ko) * 2007-01-24 2008-05-19 씨제이제일제당 (주) 코리네박테리아를 이용하여 글리세롤을 포함한탄소원으로부터 발효산물을 생산하는 방법
JP2010226956A (ja) * 2007-07-23 2010-10-14 Ajinomoto Co Inc Ｌ−リジンの製造法
WO2009093703A1 (ja) 2008-01-23 2009-07-30 Ajinomoto Co., Inc. Ｌ-アミノ酸の製造法
KR100930203B1 (ko) 2008-01-28 2009-12-07 씨제이제일제당 (주) 개량된 프로모터 및 이를 이용한 ｌ-라이신의 생산 방법
KR100987281B1 (ko) 2008-01-31 2010-10-12 씨제이제일제당 (주) 개량된 프로모터 및 이를 이용한 ｌ-라이신의 생산 방법
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KR101126041B1 (ko) * 2008-04-10 2012-03-19 씨제이제일제당 (주) 트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로형질전환된 미생물 및 이를 이용한 ｌ-라이신 생산방법
JP2010142200A (ja) 2008-12-22 2010-07-01 Ajinomoto Co Inc Ｌ−リジンの製造法
BRPI1014661B1 (pt) 2009-07-29 2020-12-15 Ajinomoto Co., Inc. Método para produzir um l-aminoácido
JP2012196144A (ja) 2009-08-03 2012-10-18 Ajinomoto Co Inc ビブリオ属細菌を用いたｌ−リジンの製造法
JP2012223091A (ja) 2009-08-25 2012-11-15 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
KR101226384B1 (ko) * 2010-03-05 2013-01-25 씨제이제일제당 (주) 개량된 프로모터 및 이를 이용한 ｌ-라이신의 생산 방법
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EP2479279A1 (de) 2011-01-20 2012-07-25 Evonik Degussa GmbH Verfahren zur fermentativen Herstellung schwefelhaltiger Aminosäuren
MY171302A (en) 2011-12-21 2019-10-08 Cj Cheiljedang Corp Method for producing l-lysine using microorganisms having ability to produce l-lysine
EP2628792A1 (de) 2012-02-17 2013-08-21 Evonik Industries AG Zelle mit verringerter ppGppase-Aktivität
ES2689754T3 (es) 2012-08-20 2018-11-15 Evonik Degussa Gmbh Procedimiento para la preparación fermentativa de L-aminoácidos utilizando cepas mejoradas de la familia Enterobacteriaceae
EP2940039A1 (de) 2014-04-30 2015-11-04 Evonik Degussa GmbH Verfahren zur Produktion von L-Aminosäuren in Corynebakterien unter Verwendung eines Glycin spaltenden Systems
DE102014208199A1 (de) 2014-04-30 2015-11-05 Evonik Degussa Gmbh Verfahren zur Produktion von L-Aminosäuren unter Verwendung eines alkaliphilen Bakteriums
EP2940143B1 (de) 2014-04-30 2020-02-05 Evonik Operations GmbH Verfahren zur Produktion von L-Aminosäuren unter Verwendung eines alkaliphilen Bakteriums
RU2729012C2 (ru) 2015-11-27 2020-08-03 Эвоник Оперейшенс ГмбХ Способ получения l-метионина
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KR102011994B1 (ko) * 2017-06-30 2019-08-20 씨제이제일제당 주식회사 신규한 아스파토키나제 변이체 및 이를 이용한 l-아미노산의 제조방법
US20240254526A1 (en) * 2018-09-07 2024-08-01 Archer Daniels Midland Company Engineered strains of corynebacteria
CN110804602B (zh) * 2019-11-18 2021-01-29 江南大学 一种L-天冬氨酸β-脱羧酶突变体及其应用
CN114292315B (zh) * 2021-12-31 2024-09-06 宁夏伊品生物科技股份有限公司 ppc突变体及其在制备L-缬氨酸中的应用

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Also Published As

Publication number Publication date
PL323545A1 (en) 1998-06-08
EP0857784A3 (en) 2002-10-16
PL190206B1 (pl) 2005-11-30
JPH10165180A (ja) 1998-06-23
CN1187539A (zh) 1998-07-15
EP0857784B1 (en) 2006-09-20
HU9702361D0 (en) 1998-03-02
HUP9702361A2 (hu) 1999-06-28
EP0857784A2 (en) 1998-08-12
BRPI9706058B1 (pt) 2015-11-03
US6221636B1 (en) 2001-04-24
DE69736699D1 (de) 2006-11-02
DK0857784T3 (da) 2007-01-15
DE69736699T2 (de) 2007-09-20
ES2273356T3 (es) 2007-05-01
HUP9702361A3 (en) 2002-12-28
SK163597A3 (en) 1998-07-08
HU224409B1 (hu) 2005-08-29
SK285146B6 (sk) 2006-07-07
CN1161470C (zh) 2004-08-11
JP4075087B2 (ja) 2008-04-16

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