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BR0109326A - Inibidores de sglt2 de glucosìdio de o-arila e método - Google Patents

Inibidores de sglt2 de glucosìdio de o-arila e método

Info

Publication number
BR0109326A
BR0109326A BR0109326-6A BR0109326A BR0109326A BR 0109326 A BR0109326 A BR 0109326A BR 0109326 A BR0109326 A BR 0109326A BR 0109326 A BR0109326 A BR 0109326A
Authority
BR
Brazil
Prior art keywords
sglt2 inhibitors
aryl glucoside
glucoside sglt2
aryl
inhibitors
Prior art date
Application number
BR0109326-6A
Other languages
English (en)
Inventor
William N Washburn
Philip M Sher
Gang Wu
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22712264&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0109326(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of BR0109326A publication Critical patent/BR0109326A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

"INIBIDORES DE SGLT2 DE GLUCOSìDIO DE O-ARILA E MéTODO". Fórmula (I) em que Quando Y é ou heteroarila; A é -O (CH~ 2~)~ m~, S, -NH(CH~ 2~)~ m~- OU (CH~ 2~)~ m~ onde n é 0-3 e m é 0-2; e R^ 1^ a R^ 6^ são conforme aqui definido. Um método é também fornecido para tratamento de diabetes e doenças relacionadas empregando uma quantidade de inibição de SGLT2 do composto acima sozinho ou em combinação com um, dois ou mais outros agentes antidiabéticos, e/ou um, dois ou mais agentes hipolipidêmicos.
BR0109326-6A 2000-03-30 2001-03-29 Inibidores de sglt2 de glucosìdio de o-arila e método BR0109326A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19309400P 2000-03-30 2000-03-30
PCT/US2001/010092 WO2001074834A1 (en) 2000-03-30 2001-03-29 O-aryl glucoside sglt2 inhibitors and method

Publications (1)

Publication Number Publication Date
BR0109326A true BR0109326A (pt) 2004-03-30

Family

ID=22712264

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0109326-6A BR0109326A (pt) 2000-03-30 2001-03-29 Inibidores de sglt2 de glucosìdio de o-arila e método

Country Status (21)

Country Link
US (1) US6683056B2 (pt)
EP (1) EP1268502B1 (pt)
JP (1) JP4986202B2 (pt)
KR (1) KR100798203B1 (pt)
CN (1) CN1275977C (pt)
AT (1) ATE316976T1 (pt)
AU (2) AU4959801A (pt)
BR (1) BR0109326A (pt)
CA (1) CA2404373A1 (pt)
DE (1) DE60117012T2 (pt)
ES (1) ES2258079T3 (pt)
HK (1) HK1049168A1 (pt)
HU (1) HUP0301513A3 (pt)
IL (1) IL151473A0 (pt)
MX (1) MXPA02009522A (pt)
NO (1) NO20024642L (pt)
NZ (1) NZ520822A (pt)
PL (1) PL365176A1 (pt)
RU (1) RU2269540C2 (pt)
WO (1) WO2001074834A1 (pt)
ZA (1) ZA200207030B (pt)

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* Cited by examiner, † Cited by third party
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