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ATE539687T1 - Selbstbetätigter applikator für eine mikroprojektionsanordnung - Google Patents

Selbstbetätigter applikator für eine mikroprojektionsanordnung

Info

Publication number
ATE539687T1
ATE539687T1 AT04796104T AT04796104T ATE539687T1 AT E539687 T1 ATE539687 T1 AT E539687T1 AT 04796104 T AT04796104 T AT 04796104T AT 04796104 T AT04796104 T AT 04796104T AT E539687 T1 ATE539687 T1 AT E539687T1
Authority
AT
Austria
Prior art keywords
self
microprojection arrangement
actuated applicator
applicator
actuated
Prior art date
Application number
AT04796104T
Other languages
English (en)
Inventor
Joseph Trautman
Lorin Olson
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of ATE539687T1 publication Critical patent/ATE539687T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/20Surgical instruments, devices or methods for vaccinating or cleaning the skin previous to the vaccination
    • A61B17/205Vaccinating by means of needles or other puncturing devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
    • A61B17/88Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
    • A61B17/92Impactors or extractors, e.g. for removing intramedullary devices
    • A61B2017/922Devices for impaction, impact element
    • A61B2017/924Impact element driving means
    • A61B2017/925Impact element driving means a spring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0023Drug applicators using microneedles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0038Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles having a channel at the side surface
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0015Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
    • A61M2037/0046Solid microneedles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Dermatology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT04796104T 2003-10-31 2004-10-21 Selbstbetätigter applikator für eine mikroprojektionsanordnung ATE539687T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US51618203P 2003-10-31 2003-10-31
PCT/US2004/035052 WO2005044333A2 (en) 2003-10-31 2004-10-21 Self-actuating applicator for microprojection array

Publications (1)

Publication Number Publication Date
ATE539687T1 true ATE539687T1 (de) 2012-01-15

Family

ID=34572872

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04796104T ATE539687T1 (de) 2003-10-31 2004-10-21 Selbstbetätigter applikator für eine mikroprojektionsanordnung

Country Status (13)

Country Link
US (2) US7097631B2 (de)
EP (1) EP1680154B1 (de)
JP (1) JP4682144B2 (de)
KR (1) KR20060099523A (de)
CN (1) CN100571643C (de)
AR (1) AR046696A1 (de)
AT (1) ATE539687T1 (de)
AU (1) AU2004287414B2 (de)
BR (1) BRPI0415629A (de)
CA (1) CA2543641A1 (de)
ES (1) ES2377647T3 (de)
TW (1) TW200633675A (de)
WO (1) WO2005044333A2 (de)

Families Citing this family (283)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3399197A (en) * 1996-06-18 1998-01-07 Alza Corporation Device for enhancing transdermal agent delivery or sampling
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
AU9682801A (en) * 2000-10-13 2002-04-22 Alza Corp Apparatus and method for piercing skin with microprotrusions
US7419481B2 (en) * 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
CA2425312C (en) * 2000-10-13 2010-02-16 Alza Corporation Microprotrusion member retainer for impact applicator
US7108681B2 (en) * 2000-10-16 2006-09-19 Corium International, Inc. Microstructures for delivering a composition cutaneously to skin
US7828827B2 (en) 2002-05-24 2010-11-09 Corium International, Inc. Method of exfoliation of skin using closely-packed microstructures
ATE428466T1 (de) * 2000-10-26 2009-05-15 Alza Corp Transdermales arzneistoffverabreichungssytem mit beschichteten mikrovorsprüngen
DE10057832C1 (de) 2000-11-21 2002-02-21 Hartmann Paul Ag Blutanalysegerät
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
WO2002074173A1 (en) * 2001-03-16 2002-09-26 Alza Corporation Method and apparatus for coating skin piercing microprojections
US20020193729A1 (en) * 2001-04-20 2002-12-19 Cormier Michel J.N. Microprojection array immunization patch and method
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7749174B2 (en) 2001-06-12 2010-07-06 Pelikan Technologies, Inc. Method and apparatus for lancet launching device intergrated onto a blood-sampling cartridge
WO2002100461A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Method and apparatus for improving success rate of blood yield from a fingerstick
US7344507B2 (en) 2002-04-19 2008-03-18 Pelikan Technologies, Inc. Method and apparatus for lancet actuation
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
DE60238914D1 (de) 2001-06-12 2011-02-24 Pelikan Technologies Inc Integriertes system zur blutprobenanalyse mit mehrfach verwendbarem probennahmemodul
DE60234597D1 (de) 2001-06-12 2010-01-14 Pelikan Technologies Inc Gerät und verfahren zur entnahme von blutproben
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7041068B2 (en) 2001-06-12 2006-05-09 Pelikan Technologies, Inc. Sampling module device and method
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
EP1404233B1 (de) 2001-06-12 2009-12-02 Pelikan Technologies Inc. Selbstoptimierende lanzettenvorrichtung mit adaptationsmittel für zeitliche schwankungen von hauteigenschaften
WO2002100460A2 (en) 2001-06-12 2002-12-19 Pelikan Technologies, Inc. Electric lancet actuator
US7344894B2 (en) 2001-10-16 2008-03-18 Agilent Technologies, Inc. Thermal regulation of fluidic samples within a diagnostic cartridge
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US8372016B2 (en) 2002-04-19 2013-02-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling and analyte sensing
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7481776B2 (en) 2002-04-19 2009-01-27 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7374544B2 (en) 2002-04-19 2008-05-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US7563232B2 (en) 2002-04-19 2009-07-21 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7708701B2 (en) 2002-04-19 2010-05-04 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7524293B2 (en) 2002-04-19 2009-04-28 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US7909778B2 (en) 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7141058B2 (en) 2002-04-19 2006-11-28 Pelikan Technologies, Inc. Method and apparatus for a body fluid sampling device using illumination
US7410468B2 (en) 2002-04-19 2008-08-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7582099B2 (en) 2002-04-19 2009-09-01 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
GB0210397D0 (en) 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
EP1475113A1 (de) * 2003-05-08 2004-11-10 Novo Nordisk A/S Externer Nadeleinsetzer
EP1624914B1 (de) 2003-05-08 2008-04-16 Novo Nordisk A/S Interne nadeleinführvorrichtung
DE602004028231D1 (de) * 2003-05-08 2010-09-02 Novo Nordisk As Eine auf die haut aufbringbare injektionsvorrichtung mit abtrennbarem betätigungsteil zum einführen der nadel
DE602004028463D1 (de) 2003-05-30 2010-09-16 Pelikan Technologies Inc Verfahren und vorrichtung zur injektion von flüssigkeit
ES2490740T3 (es) 2003-06-06 2014-09-04 Sanofi-Aventis Deutschland Gmbh Aparato para toma de muestras de fluido sanguíneo y detección de analitos
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
EP1635700B1 (de) 2003-06-13 2016-03-09 Sanofi-Aventis Deutschland GmbH Gerät für eine point of care vorrichtung
US20050123507A1 (en) * 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
MXPA06000281A (es) * 2003-06-30 2006-07-03 Johnson & Johnson Formulaciones para microproyecciones revestidas que contienen contraiones no volatiles.
EP1502613A1 (de) 2003-08-01 2005-02-02 Novo Nordisk A/S Gerät mit Rückziehvorrichting für eine Nadel
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
US9351680B2 (en) 2003-10-14 2016-05-31 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a variable user interface
AU2004285484A1 (en) * 2003-10-24 2005-05-12 Alza Corporation Pretreatment method and system for enhancing transdermal drug delivery
WO2005044139A2 (en) * 2003-10-28 2005-05-19 Alza Corporation Method and apparatus for reducing the incidence of tobacco use
EP1680154B1 (de) 2003-10-31 2012-01-04 ALZA Corporation Selbstbetätigter applikator für eine mikroprojektionsanordnung
EP1706171A1 (de) * 2003-12-29 2006-10-04 3M Innovative Properties Company Medizinprodukte und diese enthaltende sets
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
EP1706026B1 (de) 2003-12-31 2017-03-01 Sanofi-Aventis Deutschland GmbH Verfahren und vorrichtung zur verbesserung der fluidströmung und der probennahme
GB0402131D0 (en) 2004-01-30 2004-03-03 Isis Innovation Delivery method
JP5085317B2 (ja) * 2004-03-24 2012-11-28 コリウム インターナショナル, インコーポレイテッド 経皮送達デバイス
KR101158939B1 (ko) 2004-03-26 2012-06-21 우노메디컬 에이/에스 주사세트를 위한 주사장치
CN100586495C (zh) 2004-03-30 2010-02-03 诺和诺德公司 包括杠杆机构的致动器系统
WO2005103303A2 (en) * 2004-04-13 2005-11-03 Alza Corporation Apparatus and method for transdermal delivery of multiple vaccines
CA2566032A1 (en) * 2004-05-13 2005-12-01 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
US7591806B2 (en) * 2004-05-18 2009-09-22 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
EP1765194A4 (de) 2004-06-03 2010-09-29 Pelikan Technologies Inc Verfahren und gerät für eine flüssigkeitsentnahmenvorrichtung
WO2005123173A1 (en) * 2004-06-10 2005-12-29 3M Innovative Properties Company Patch application device and kit
US8062250B2 (en) 2004-08-10 2011-11-22 Unomedical A/S Cannula device
CN101232874A (zh) * 2004-08-11 2008-07-30 阿尔扎公司 透皮递送利钠肽的装置和方法
MX2007002795A (es) * 2004-09-08 2008-03-05 Johnson & Johnson Arreglo de microproyeccion con adhesion y adaptacion a la piel, mejoradas.
US9174035B2 (en) 2004-11-18 2015-11-03 3M Innovative Properties Company Microneedle array applicator and retainer
CN101060883B (zh) 2004-11-18 2010-06-23 3M创新有限公司 低轮廓微针阵列施放器
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
US20090054811A1 (en) * 2004-12-30 2009-02-26 Dirk Boecker Method and apparatus for analyte measurement test time
US20090076451A1 (en) 2005-01-24 2009-03-19 Nova Nordisk A/S Medical Device with Protected Transcutaneous Device
US7985199B2 (en) 2005-03-17 2011-07-26 Unomedical A/S Gateway system
WO2006108185A1 (en) 2005-04-07 2006-10-12 3M Innovative Properties Company System and method for tool feedback sensing
US8048017B2 (en) * 2005-05-18 2011-11-01 Bai Xu High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
US8043250B2 (en) * 2005-05-18 2011-10-25 Nanomed Devices, Inc. High-aspect-ratio microdevices and methods for transdermal delivery and sampling of active substances
WO2007002523A2 (en) 2005-06-24 2007-01-04 3M Innovative Properties Company Collapsible patch with microneedle array
EP2474338B1 (de) * 2005-06-27 2013-07-24 3M Innovative Properties Company Vorrichtung zum Aufbringen einer Mikronadelanordnung
WO2007033015A1 (en) * 2005-09-12 2007-03-22 Alza Corporation Coatable transdermal delivery microprojection assembly
PL1762259T3 (pl) * 2005-09-12 2011-03-31 Unomedical As Urządzenie wprowadzające, przeznaczone do zestawu infuzyjnego, z pierwszą i drugą jednostką sprężynową
DK1962926T3 (da) 2005-12-23 2009-09-28 Unomedical As Injektionsanordning
CA2642415A1 (en) 2006-02-28 2007-09-07 Unomedical A/S Inserter for infusion part and infusion part provided with needle protector
US9173992B2 (en) * 2006-03-13 2015-11-03 Novo Nordisk A/S Secure pairing of electronic devices using dual means of communication
JP2009529930A (ja) * 2006-03-13 2009-08-27 ノボ・ノルデイスク・エー/エス 二目的通信手段を備えた医療システム
CA2680690A1 (en) * 2006-03-15 2007-09-20 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents to prevent or treat osteopenia
US9119945B2 (en) * 2006-04-20 2015-09-01 3M Innovative Properties Company Device for applying a microneedle array
WO2007127815A2 (en) * 2006-04-25 2007-11-08 Alza Corporation Microprojection array application with multilayered microprojection member for high drug loading
US20070293816A1 (en) * 2006-04-25 2007-12-20 Alza Corporation Microprojection Array Application with Grouped Microprojections for High Drug Loading
CN101460207B (zh) 2006-06-06 2012-03-21 诺沃-诺迪斯克有限公司 包括皮肤可安装设备及其包装件的组件
AU2007256561B2 (en) 2006-06-07 2012-07-19 Unomedical A/S Inserter for transcutaneous sensor
MX2008015247A (es) 2006-06-09 2008-12-15 Unomedical As Almohadilla de montaje.
US20100004597A1 (en) * 2006-08-02 2010-01-07 Unomedical A/S Insertion Device
JP2009545341A (ja) * 2006-08-02 2009-12-24 ウノメディカル アクティーゼルスカブ カニューレ及び送出デバイス
EP1917990A1 (de) 2006-10-31 2008-05-07 Unomedical A/S Infusionsset
WO2008053481A1 (en) * 2006-11-01 2008-05-08 Svip 6 Llc Microneedle arrays
US20080214987A1 (en) * 2006-12-22 2008-09-04 Nanomed Devices, Inc. Microdevice And Method For Transdermal Delivery And Sampling Of Active Substances
US10525246B2 (en) 2006-12-22 2020-01-07 Nanomed Skincare, Inc. Microdevice and method for transdermal delivery and sampling of active substances
EP2121111B1 (de) * 2007-01-22 2018-03-14 Corium International, Inc. Applikator für mikronadelanordnung
CA2676811A1 (en) * 2007-02-02 2008-08-07 Unomedical A/S Injection site for injecting medication
KR20090117749A (ko) * 2007-02-02 2009-11-12 우노메디컬 에이/에스 약물 공급장치
US8911749B2 (en) 2007-04-16 2014-12-16 Corium International, Inc. Vaccine delivery via microneedle arrays
EP2146689B1 (de) 2007-04-16 2020-08-12 Corium, Inc. Einen wirkstoff enthaltende lösungsmittel-gegossene mikronadelanordnungen
RU2469751C2 (ru) 2007-06-20 2012-12-20 Уномедикал А/С Способ изготовления катетера и устройство для его осуществления
CN101808685A (zh) 2007-07-03 2010-08-18 优诺医疗有限公司 具有双稳平衡状态的插入器
KR20100062991A (ko) 2007-07-10 2010-06-10 우노메디컬 에이/에스 두 개의 스프링을 갖는 인서터
AU2008277763B2 (en) 2007-07-18 2011-11-10 Unomedical A/S Insertion device with pivoting action
CA2988753A1 (en) 2007-08-06 2009-02-12 Serenity Pharmaceuticals, Llc Methods and devices for desmopressin drug delivery
CA2699875A1 (en) * 2007-09-17 2009-03-26 Icu Medical, Inc. Insertion devices for infusion devices
GB0719577D0 (en) * 2007-10-08 2007-11-14 Kirby Andrew J Microimplant devices and methods of making and use thereof
JP5178132B2 (ja) * 2007-10-11 2013-04-10 キヤノン株式会社 画像処理システム並びに画像処理方法
CA2701772A1 (en) 2007-10-31 2009-05-07 Novo Nordisk A/S Non-porous material as sterilization barrier
US9220678B2 (en) 2007-12-24 2015-12-29 The University Of Queensland Coating method
US8883015B2 (en) 2008-02-07 2014-11-11 The University Of Queensland Patch production
PL2252349T3 (pl) 2008-02-13 2012-01-31 Unomedical As Uszczelnienie między częścią kaniulową a drogą przepływu płynu
WO2009103759A1 (en) 2008-02-20 2009-08-27 Unomedical A/S Insertion device with horizontally moving part
EP2265324B1 (de) 2008-04-11 2015-01-28 Sanofi-Aventis Deutschland GmbH Integriertes System zur Messung von Analyten
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
PT3225250T (pt) * 2008-05-21 2019-10-15 Ferring Bv Desmopressina orodispersivel para aumentar o periodo inicial de sono não perturbado pela nocturia
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
AU2009250341A1 (en) 2008-05-23 2009-11-26 The University Of Queensland Analyte detection using a needle projection patch
US20100069726A1 (en) * 2008-06-04 2010-03-18 Seventh Sense Biosystems, Inc. Compositions and methods for rapid one-step diagnosis
US20110223204A1 (en) * 2008-06-04 2011-09-15 Bradford J Duft Treatment of pain with gap junction modulation compounds
PT3187219T (pt) 2008-12-02 2020-07-21 Allergan Inc Dispositivo de injeção
MX2011005735A (es) 2008-12-22 2011-06-21 Unomedical As Dispositivo medico que comprende una almohadilla de adhesivo.
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
US9033898B2 (en) 2010-06-23 2015-05-19 Seventh Sense Biosystems, Inc. Sampling devices and methods involving relatively little pain
CN104434136A (zh) 2009-03-02 2015-03-25 第七感生物系统有限公司 用于抽出血液的装置
WO2012018486A2 (en) 2010-07-26 2012-02-09 Seventh Sense Biosystems, Inc. Rapid delivery and/or receiving of fluids
KR101030752B1 (ko) * 2009-04-09 2011-04-26 한국생명공학연구원 유체전달을 조절할 수 있는 마이크로 니들 유닛
SG10201401744QA (en) * 2009-04-23 2014-08-28 Univ Singapore An apparatus that includes nano-sized projections and a method for manufacture thereof
WO2010124255A2 (en) * 2009-04-24 2010-10-28 Corium International, Inc. Methods for manufacturing microprojection arrays
EP2424611A4 (de) * 2009-05-01 2012-10-24 Nanbu Plastics Co Ltd Vorrichtung für transdermale verabreichungen
WO2011005971A1 (en) * 2009-07-09 2011-01-13 Cook Incorporated Spring action medical device
CA2766475A1 (en) 2009-07-30 2011-02-03 Unomedical A/S Inserter device with horizontal moving part
RU2508135C2 (ru) 2009-07-31 2014-02-27 3М Инновейтив Пропертиз Компани Матрица полых микроигл
WO2011015659A1 (en) 2009-08-07 2011-02-10 Unomedical A/S Delivery device with sensor and one or more cannulas
EP2493535A2 (de) * 2009-10-30 2012-09-05 Seventh Sense Biosystems, Inc. Systeme und verfahren zur anwendung auf der haut und zur steuerung ihrer betätigung, freisetzung und/oder wahrnehmung
CA2780294C (en) 2009-11-09 2018-01-16 Spotlight Technology Partners Llc Polysaccharide based hydrogels
EP2498764B1 (de) 2009-11-09 2017-09-06 Spotlight Technology Partners LLC Fragmentierte hydrogele
WO2011065972A2 (en) * 2009-11-24 2011-06-03 Seventh Sense Biosystems, Inc. Patient-enacted sampling technique
US20110172638A1 (en) * 2010-01-08 2011-07-14 Ratio, Inc. Drug delivery device including multi-functional cover
WO2011088211A2 (en) * 2010-01-13 2011-07-21 Seventh Sense Biosystems, Inc. Sampling device interfaces
JP5806236B2 (ja) * 2010-01-13 2015-11-10 セブンス センス バイオシステムズ,インコーポレーテッド 流体の急速送達および/また採取
WO2011094573A1 (en) 2010-01-28 2011-08-04 Seventh Sense Biosystems, Inc. Monitoring or feedback systems and methods
US8911422B2 (en) 2010-02-24 2014-12-16 Hisamitsu Pharmaceutical Co., Inc. Micro-needle device
BR112012024635A2 (pt) 2010-03-30 2017-08-08 Unomedical As dispositivo médico
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9687641B2 (en) 2010-05-04 2017-06-27 Corium International, Inc. Method and device for transdermal delivery of parathyroid hormone using a microprojection array
RU2569029C2 (ru) 2010-05-04 2015-11-20 Кориум Интернэшнл, Инк. Аппликаторы для микроигл
MX342898B (es) 2010-05-12 2016-10-18 Radius Health Inc * Regimen terapéutico de la sal de diclorhidrato del (r) -6-(2-(etil (4-2(etilamino) etil) bencil) amino)-4-metoxifenil)-5, 6,7,8-tetrahidronaftaleno-2-ol.
US9943673B2 (en) 2010-07-14 2018-04-17 Vaxxas Pty Limited Patch applying apparatus
ES2561824T3 (es) 2010-07-16 2016-03-01 Seventh Sense Biosystems, Inc. Ambiente a baja presión para dispositivos de transferencia de fluidos
WO2012021801A2 (en) 2010-08-13 2012-02-16 Seventh Sense Biosystems, Inc. Systems and techniques for monitoring subjects
EP2433663A1 (de) 2010-09-27 2012-03-28 Unomedical A/S Einführsystem
AU2011312490B2 (en) 2010-09-28 2015-06-25 Radius Pharmaceuticals, Inc. Selective androgen receptor modulators
EP2436412A1 (de) 2010-10-04 2012-04-04 Unomedical A/S Sprinklerkanüle
JP5885667B2 (ja) * 2010-10-07 2016-03-15 久光製薬株式会社 アプリケータ
US9017289B2 (en) * 2010-11-03 2015-04-28 Covidien Lp Transdermal fluid delivery device
WO2012061556A1 (en) 2010-11-03 2012-05-10 Flugen, Inc. Wearable drug delivery device having spring drive and sliding actuation mechanism
JP2012100783A (ja) * 2010-11-08 2012-05-31 Nanbu Plastics Co Ltd 薬液供給装置
JP6055773B2 (ja) 2010-11-09 2016-12-27 セブンス センス バイオシステムズ,インコーポレーテッド 血液サンプリングのためのシステムおよびインターフェース
EP2643045A4 (de) * 2010-11-23 2016-01-13 Presage Biosciences Inc Therapeutische verfahren und zusammensetzungen zur abgabe in fester form
US8814831B2 (en) * 2010-11-30 2014-08-26 Becton, Dickinson And Company Ballistic microneedle infusion device
EP2460553A1 (de) * 2010-12-02 2012-06-06 Debiotech S.A. Vorrichtung für das Einsetzen von Nadeln
CA2822428A1 (en) 2010-12-22 2012-06-28 Valeritas, Inc. Microneedle patch applicator
CN103917242A (zh) 2011-04-22 2014-07-09 半径健康公司 PTH、PTHrP和相关肽的药物递送方法
EP3236259A1 (de) 2011-04-29 2017-10-25 Seventh Sense Biosystems, Inc. Plasma- oder serumherstellung und entfernung von flüssigkeiten bei reduziertem druck
US20130158468A1 (en) 2011-12-19 2013-06-20 Seventh Sense Biosystems, Inc. Delivering and/or receiving material with respect to a subject surface
WO2012149155A1 (en) 2011-04-29 2012-11-01 Seventh Sense Biosystems, Inc. Systems and methods for collecting fluid from a subject
KR102237667B1 (ko) 2011-04-29 2021-04-12 세븐쓰 센스 바이오시스템즈, 인크. 유체들의 전달 및/또는 수용
US20140207101A1 (en) * 2011-06-09 2014-07-24 3M Innovative Properties Company Microstructure device with removable microstructure patch
CN103687643B (zh) * 2011-07-27 2016-04-20 久光制药株式会社 施放器
US10076649B2 (en) 2011-09-07 2018-09-18 3M Innovative Properties Company Delivery system for hollow microneedle arrays
NL2007461C2 (en) * 2011-09-23 2013-03-26 Ambro B V System for transporting fluid across or into a biological barrier, device and capsule as part of the system.
WO2013050277A1 (en) 2011-10-05 2013-04-11 Unomedical A/S Inserter for simultaneous insertion of multiple transcutaneous parts
EP2764887B1 (de) * 2011-10-06 2020-12-02 Hisamitsu Pharmaceutical Co., Inc. Applikator
EP2766066B8 (de) * 2011-10-12 2021-01-20 Kindeva Drug Delivery L.P. Integriertes abgabesystem für mikronadelanordnungen
EP2765927B1 (de) 2011-10-12 2021-02-24 Vaxxas Pty Limited Abgabegerät
KR20140074383A (ko) * 2011-10-12 2014-06-17 쓰리엠 이노베이티브 프로퍼티즈 컴파니 통합형 마이크로니들 어레이 전달 시스템
EP2583715A1 (de) 2011-10-19 2013-04-24 Unomedical A/S Infusionsschlauchsystem und Herstellungsverfahren
US9440051B2 (en) 2011-10-27 2016-09-13 Unomedical A/S Inserter for a multiplicity of subcutaneous parts
US20140323907A1 (en) 2011-10-28 2014-10-30 Jason Frazier Methods for drug delivery
DE102011119055B4 (de) * 2011-11-16 2013-08-14 Lts Lohmann Therapie-Systeme Ag Zylinder-Kolben-Einheit mit Klebescheibe II
JP6226862B2 (ja) * 2012-04-05 2017-11-08 久光製薬株式会社 穿刺装置及びその製造方法
DE202012006290U1 (de) * 2012-06-29 2013-09-30 Lukas Pregenzer Inkontinenzimplantat
JP6091818B2 (ja) * 2012-08-28 2017-03-08 コスメディ製薬株式会社 マイクロニードルパッチ投与装置
EP2906284B8 (de) 2012-10-10 2021-01-20 Kindeva Drug Delivery L.P. Kraftgesteuerter applikator zum auftragen einer mikronadelvorrichtung auf der haut
MX375307B (es) 2012-12-21 2025-03-06 Corium Inc Microarreglo para la entrega de agente terapeutico y metodos de uso.
CN104902943B (zh) * 2013-01-08 2017-10-31 3M创新有限公司 用于向皮肤施用微针装置的施用装置
AU2014249471B2 (en) * 2013-03-12 2019-01-24 Corium Pharma Solutions, Inc. Microprojection applicators
CA2903763C (en) 2013-03-15 2021-11-16 Corium International, Inc. Microarray with polymer-free microstructures, methods of making, and methods of use
AU2014237357B2 (en) * 2013-03-15 2019-11-28 Corium Pharma Solutions, Inc. Multiple impact microprojection applicators and methods of use
ES2908339T3 (es) 2013-03-15 2022-04-28 Corium Inc Micromatriz para el suministro de un agente terapéutico y métodos de uso
US9962534B2 (en) 2013-03-15 2018-05-08 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
US20140350516A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Mechanical syringe accessory
US20140350518A1 (en) 2013-05-23 2014-11-27 Allergan, Inc. Syringe extrusion accessory
JP6494602B2 (ja) 2013-05-31 2019-04-03 スリーエム イノベイティブ プロパティズ カンパニー 二重カバーを備えるマイクロニードル注射装置
KR102274902B1 (ko) 2013-05-31 2021-07-07 쓰리엠 이노베이티브 프로퍼티즈 컴파니 마이크로니들 주사 및 주입 장치 및 그의 사용 방법
PL3003459T3 (pl) 2013-05-31 2018-11-30 3M Innovative Properties Company Mikroigłowy aparat iniekcyjny zawierający odwrócony element wykonawczy
US20150038897A1 (en) 2013-07-30 2015-02-05 Zosano Pharma, Inc. Low-Profile Microneedle Patch Applicator
EP3047871B1 (de) * 2013-09-18 2018-05-02 Cosmed Pharmaceutical Co., Ltd. Applikationsvorrichtung für mikronadelpflaster und pflasterhalter
DE102013021058B4 (de) * 2013-12-18 2017-10-12 Gerresheimer Regensburg Gmbh Vorrichtung zur Applizierung eines Nadelarrays auf biologischem Gewebe
GB201401133D0 (en) 2014-01-23 2014-03-12 Renephra Ltd Fluid extraction device, applicator device and associated methods
CN106061546A (zh) * 2014-02-10 2016-10-26 Lts勒曼治疗系统股份公司 微针系统及其制造方法
US10029048B2 (en) 2014-05-13 2018-07-24 Allergan, Inc. High force injection devices
US20160038434A1 (en) * 2014-08-01 2016-02-11 Innovative Drive Corporation Device and method for application of a transdermal membrane
US10624843B2 (en) 2014-09-04 2020-04-21 Corium, Inc. Microstructure array, methods of making, and methods of use
US10226585B2 (en) 2014-10-01 2019-03-12 Allergan, Inc. Devices for injection and dosing
EP4218892A1 (de) 2015-02-02 2023-08-02 Vaxxas Pty Limited Mikroprojektionsarrayapplikator
RU2715685C2 (ru) 2015-03-10 2020-03-02 Аллерган Фармасьютикалз Холдингз (Айрленд) Анлимитед Кампани Многоигольное инъекционное устройство
CN108135177B (zh) 2015-04-29 2021-06-01 雷迪厄斯制药公司 用于治疗癌症的方法
WO2017004067A1 (en) 2015-06-29 2017-01-05 Corium International, Inc. Microarray for delivery of therapeutic agent, methods of use, and methods of making
JP2017023404A (ja) * 2015-07-22 2017-02-02 日本写真印刷株式会社 マイクロニードルパッチ用インパクト付加型アプリケータ及び先端部材
US11103259B2 (en) 2015-09-18 2021-08-31 Vaxxas Pty Limited Microprojection arrays with microprojections having large surface area profiles
CA2999538A1 (en) 2015-09-28 2017-04-06 Vaxxas Pty Limited Microprojection arrays with enhanced skin penetrating properties and methods thereof
CN112089961B (zh) * 2015-12-21 2022-08-09 美德阿利克斯株式会社 微针贴片施用器及其壳体
US9918932B2 (en) 2016-02-19 2018-03-20 Zosano Pharma Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines
AU2017232609B2 (en) 2016-03-16 2022-01-13 Cosmed Pharmaceutical Co., Ltd. Microneedle patch case
EP3439716B1 (de) 2016-04-08 2023-11-01 Allergan, Inc. Aspirations- und injektionsvorrichtung
CN105999259A (zh) * 2016-05-11 2016-10-12 长春海基亚生物技术股份有限公司 无针注射狂犬病疫苗系统与应用
WO2017198872A1 (en) 2016-05-20 2017-11-23 Uprax System and method for applying microneedles
AU2017281038B2 (en) 2016-06-22 2021-09-09 Ellipses Pharma Ltd AR+ breast cancer treatment methods
CA3047307A1 (en) * 2016-12-16 2018-06-21 Sorrento Therapeutics, Inc. Application device for a fluid delivery apparatus and method of use
EP3560545B1 (de) * 2016-12-20 2021-05-26 Hisamitsu Pharmaceutical Co., Inc. Applikator
CN110191707A (zh) 2017-01-05 2019-08-30 雷迪厄斯制药公司 Rad1901-2hcl的多晶型形式
CA3050418A1 (en) 2017-01-25 2018-08-02 Cosmed Pharmaceutical Co., Ltd. Microneedle patch applying device
USD867582S1 (en) 2017-03-24 2019-11-19 Allergan, Inc. Syringe device
JP6931217B2 (ja) 2017-03-28 2021-09-01 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ
CN115923337A (zh) 2017-03-31 2023-04-07 瓦克萨斯私人有限公司 用于涂覆表面的设备和方法
JP2018191783A (ja) * 2017-05-15 2018-12-06 富士フイルム株式会社 マイクロニードルアレイユニット、および容器
EP3639010A4 (de) 2017-06-13 2021-03-17 Vaxxas Pty Limited Qualitätskontrolle von substratbeschichtungen
EP4218893A1 (de) 2017-08-04 2023-08-02 Vaxxas Pty Limited Kompakter hoher mechanischer energiespeicher und aktuator mit geringer auslösekraft für die abgabe von mikroprojektions-array-patches (map)
US10430138B2 (en) * 2017-08-10 2019-10-01 Canon Kabushiki Kaisha Communication apparatus
US11660264B2 (en) 2017-08-23 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
KR20210155817A (ko) 2017-08-23 2021-12-23 조사노 파마 코포레이션 편두통 및 군발성 두통의 치료를 위한 졸미트립탄의 치료적 농도를 신속하게 달성하는 방법
IL273926B2 (en) 2017-10-17 2024-06-01 3M Innovative Properties Company Conductor for applying a micro-needle array to the skin
JP7033886B2 (ja) * 2017-11-07 2022-03-11 ニプロ株式会社 穿刺用器具
EP3727556A1 (de) * 2017-12-19 2020-10-28 Kindeva Drug Delivery L.P. Mikroarray-applikator
EP3744374A4 (de) 2018-01-24 2021-11-03 Cosmed Pharmaceutical Co., Ltd. Festbindende vorrichtung für mikronadel
US11660265B2 (en) 2018-06-28 2023-05-30 Emergex USA Corporation Method of rapidly achieving therapeutic concentrations of triptans for treatment of migraines and cluster headaches
SG11202013177WA (en) 2018-07-04 2021-01-28 Radius Pharmaceuticals Inc Polymorphic forms of rad 1901-2hcl
JP7172293B2 (ja) * 2018-08-30 2022-11-16 ニプロ株式会社 マイクロニードルアプリケータ
JP7099189B2 (ja) * 2018-08-30 2022-07-12 ニプロ株式会社 マイクロニードルアプリケータ
KR20210086599A (ko) * 2018-08-30 2021-07-08 니프로 가부시키가이샤 마이크로 니들 어플리케이터
US11246997B2 (en) * 2018-09-25 2022-02-15 Palo Alto Research Center Incorporated Handheld filament extension atomizer for precision delivery of drugs and therapeutics
CN109364364B (zh) * 2018-12-10 2021-06-22 徐爱梅 一种皮肤科涂药装置
DE102019200563A1 (de) * 2019-01-17 2020-07-23 Lts Lohmann Therapie-Systeme Ag Applikator
JP7491551B2 (ja) 2019-04-25 2024-05-28 コスメディ製薬株式会社 水溶性シート状製剤のアプリケータ2
EP3989824B1 (de) * 2019-06-25 2024-12-04 William Ma Ummantelte schneidvorrichtung
CN111685867B (zh) * 2020-06-22 2020-12-01 镇江恒生涓恩医疗器械有限公司 一种多级稳定型消融电极
EP3974017A1 (de) * 2020-09-28 2022-03-30 Latch Medical System zur anwendung eines mikronadel-patch
CN114748778B (zh) * 2021-01-11 2024-05-03 苏州纳生微电子有限公司 传动结构、应用传动结构的给液装置及其使用方法
EP4301225A1 (de) 2021-09-28 2024-01-10 Biolinq Incorporated Mikronadelgehäuse und applikatorvorrichtung für eine vorrichtung zur kontinuierlichen analytüberwachung auf mikronadelarraybasis
USD1033641S1 (en) 2021-12-17 2024-07-02 Biolinq Incorporated Microneedle array sensor applicator device
USD1057153S1 (en) 2022-04-29 2025-01-07 Biolinq Incorporated Microneedle array sensor applicator device
WO2024097385A1 (en) * 2022-11-05 2024-05-10 Kindeva Drug Delivery L.P. Microneedle array applicator and system

Family Cites Families (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE25637E (en) 1964-09-08 Means for vaccinating
US3136314A (en) * 1960-08-01 1964-06-09 Kravitz Harvey Vaccinating devices
US3964482A (en) * 1971-05-17 1976-06-22 Alza Corporation Drug delivery device
BE795384A (fr) * 1972-02-14 1973-08-13 Ici Ltd Pansements
OA05448A (fr) * 1975-10-16 1981-03-31 Manufrance Manufacture Francai Dispositif vaccinateur multipénétrant.
GB2064329B (en) * 1979-11-01 1983-06-22 Matburn Holdings Ltd Multiple puncture apparatus
FR2474856A1 (fr) * 1980-01-31 1981-08-07 Merieux Inst Dispositif scarificateur
US4535769A (en) * 1981-03-23 1985-08-20 Becton, Dickinson And Company Automatic retractable lancet assembly
EP0429842B1 (de) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Vorrichtung zur transdermalen Applikation von Protein- oder Peptid-Medikamenten
US5279544A (en) 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
FR2696334B1 (fr) * 1992-10-01 1994-12-02 Boudjema J Pascal Dispositif pour transplantation de greffons capillaires de petit diamètre.
US5439473A (en) * 1993-12-13 1995-08-08 Modulohm A/S Safety lancet
US5350392A (en) * 1994-02-03 1994-09-27 Miles Inc. Lancing device with automatic cocking
US5487726A (en) * 1994-06-16 1996-01-30 Ryder International Corporation Vaccine applicator system
EP0796128B1 (de) 1994-12-09 1999-03-10 Novartis AG Transdermales system
AU5869796A (en) 1995-05-22 1996-12-11 Ned A. Godshall Micromechanical patch for enhancing the delivery of compound s through the skin
AU5740496A (en) 1995-05-22 1996-12-11 General Hospital Corporation, The Micromechanical device and method for enhancing delivery of compounds through the skin
DE19525607A1 (de) 1995-07-14 1997-01-16 Boehringer Ingelheim Kg Transcorneales Arzneimittelfreigabesystem
DE29723371U1 (de) 1996-05-17 1998-08-06 Mercury Diagnostics, Inc., Palo Alto, Calif. Vorrichtung zum Ausdrücken von Körperflüssigkeit aus einem Einstich
AU3399197A (en) 1996-06-18 1998-01-07 Alza Corporation Device for enhancing transdermal agent delivery or sampling
CA2259437C (en) 1996-07-03 2006-12-05 Altea Technologies, Inc. Multiple mechanical microporation of skin or mucosa
WO1998011937A1 (en) 1996-09-17 1998-03-26 Deka Products Limited Partnership System for delivery of drugs by transport
CA2271167C (en) 1996-12-20 2007-01-09 Alza Corporation Device and method for enhancing transdermal agent flux
DE19654391A1 (de) 1996-12-27 1998-07-02 Basf Ag Katalysator zur selektiven Herstellung von Propylen aus Propan
WO1998029298A1 (en) 1996-12-31 1998-07-09 Shell Internationale Research Maatschappij B.V. Spar platform with vertical slots
US5964718A (en) 1997-11-21 1999-10-12 Mercury Diagnostics, Inc. Body fluid sampling device
US6918901B1 (en) 1997-12-10 2005-07-19 Felix Theeuwes Device and method for enhancing transdermal agent flux
DE69839969D1 (de) 1997-12-11 2008-10-16 Alza Corp Vorrichtung zur verbesserung des transdermalen flusses von medikamenten
ATE221400T1 (de) 1997-12-11 2002-08-15 Alza Corp Vorrichtung zur erhöhung des transdermalen wirkstoffeflusses
DK1037686T3 (da) 1997-12-11 2006-01-02 Alza Corp Apparat til forögelse af transdermal gennemströmning af midler
WO1999064580A1 (en) 1998-06-10 1999-12-16 Georgia Tech Research Corporation Microneedle devices and methods of manufacture and use thereof
US6743211B1 (en) * 1999-11-23 2004-06-01 Georgia Tech Research Corporation Devices and methods for enhanced microneedle penetration of biological barriers
US6611707B1 (en) * 1999-06-04 2003-08-26 Georgia Tech Research Corporation Microneedle drug delivery device
US6835184B1 (en) * 1999-09-24 2004-12-28 Becton, Dickinson And Company Method and device for abrading skin
US6248120B1 (en) * 2000-01-10 2001-06-19 P. Z. “HTL” Spolka Akcyjna Puncturing device
US6537242B1 (en) * 2000-06-06 2003-03-25 Becton, Dickinson And Company Method and apparatus for enhancing penetration of a member for the intradermal sampling or administration of a substance
US6533949B1 (en) * 2000-08-28 2003-03-18 Nanopass Ltd. Microneedle structure and production method therefor
AU9682801A (en) 2000-10-13 2002-04-22 Alza Corp Apparatus and method for piercing skin with microprotrusions
CA2425312C (en) * 2000-10-13 2010-02-16 Alza Corporation Microprotrusion member retainer for impact applicator
HUP0303583A2 (en) 2000-10-13 2004-01-28 Alza Corp Microblade array impact applicator
US7419481B2 (en) 2000-10-13 2008-09-02 Alza Corporation Apparatus and method for piercing skin with microprotrusions
ATE428466T1 (de) * 2000-10-26 2009-05-15 Alza Corp Transdermales arzneistoffverabreichungssytem mit beschichteten mikrovorsprüngen
WO2002074173A1 (en) 2001-03-16 2002-09-26 Alza Corporation Method and apparatus for coating skin piercing microprojections
JP2004528900A (ja) 2001-04-20 2004-09-24 アルザ・コーポレーシヨン 有益な作用物質を含有するコーティングを有する微小突起アレイ
US7429258B2 (en) * 2001-10-26 2008-09-30 Massachusetts Institute Of Technology Microneedle transport device
EP1485317A2 (de) 2001-11-30 2004-12-15 Alza Corporation Verfahren und vorrichtungen zur herstellung von mikroprojektoranordnungen
ES2297056T3 (es) 2001-12-20 2008-05-01 Alza Corporation Micro-proyecciones para perforacion de la piel que tienen control de la profundidad de perforacion.
AU2003209645A1 (en) * 2002-03-04 2003-09-16 Nano Pass Technologies Ltd. Devices and methods for transporting fluid across a biological barrier
US6945952B2 (en) * 2002-06-25 2005-09-20 Theraject, Inc. Solid solution perforator for drug delivery and other applications
JP2006500974A (ja) 2002-06-28 2006-01-12 アルザ・コーポレーシヨン 被覆され微細突起物を有する経皮的薬物送達装置
CN102872526A (zh) * 2002-07-19 2013-01-16 3M创新有限公司 微针装置和微针施用设备
AR042815A1 (es) 2002-12-26 2005-07-06 Alza Corp Dispositivo de suministro de agente activo que tiene miembros compuestos
MXPA06000281A (es) 2003-06-30 2006-07-03 Johnson & Johnson Formulaciones para microproyecciones revestidas que contienen contraiones no volatiles.
US20050123507A1 (en) 2003-06-30 2005-06-09 Mahmoud Ameri Formulations for coated microprojections having controlled solubility
BRPI0415967A (pt) 2003-10-28 2007-01-23 Alza Corp aplicação de conjugados de polìmero de peptìdeos e proteìnas terapêuticos através de microprojeções revestidas
EP1680154B1 (de) 2003-10-31 2012-01-04 ALZA Corporation Selbstbetätigter applikator für eine mikroprojektionsanordnung
JP5388415B2 (ja) 2003-11-13 2014-01-15 アルザ・コーポレーシヨン 経皮送達のための組成物及び装置
CA2566032A1 (en) 2004-05-13 2005-12-01 Alza Corporation Apparatus and method for transdermal delivery of parathyroid hormone agents
US20060188555A1 (en) 2005-01-21 2006-08-24 Micheal Cormier Therapeutic peptide formulations with improved stability
US20060177494A1 (en) 2005-01-31 2006-08-10 Micheal Cormier Coated microprojections having reduced variability and method for producing same
WO2006089285A1 (en) 2005-02-16 2006-08-24 Alza Corporation Microprojection arrays with improved biocompatibility
EP1885405A1 (de) 2005-06-02 2008-02-13 Alza Corporation, Inc. Verfahren zur endsterilisierung von vorrichtungen zur transdermalen verabreichung
WO2007002123A2 (en) 2005-06-21 2007-01-04 Alza Corporation Method and device for coating a continuous strip of microprojection members

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CN1901840A (zh) 2007-01-24
WO2005044333A3 (en) 2006-06-01
US7097631B2 (en) 2006-08-29
EP1680154A2 (de) 2006-07-19
AR046696A1 (es) 2005-12-21
BRPI0415629A (pt) 2006-12-12
TW200633675A (en) 2006-10-01
KR20060099523A (ko) 2006-09-19
ES2377647T3 (es) 2012-03-29
AU2004287414A1 (en) 2005-05-19
CN100571643C (zh) 2009-12-23
AU2004287414B2 (en) 2010-11-25
JP4682144B2 (ja) 2011-05-11
US20070027427A1 (en) 2007-02-01
EP1680154A4 (de) 2007-07-18
WO2005044333A2 (en) 2005-05-19
EP1680154B1 (de) 2012-01-04
US20050096586A1 (en) 2005-05-05
JP2007509706A (ja) 2007-04-19
CA2543641A1 (en) 2005-05-19
US9421351B2 (en) 2016-08-23

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