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ATE513039T1 - Nukleinsäureisolationsmethode und entsprechender reagentiensatz dafür - Google Patents

Nukleinsäureisolationsmethode und entsprechender reagentiensatz dafür

Info

Publication number
ATE513039T1
ATE513039T1 AT00989419T AT00989419T ATE513039T1 AT E513039 T1 ATE513039 T1 AT E513039T1 AT 00989419 T AT00989419 T AT 00989419T AT 00989419 T AT00989419 T AT 00989419T AT E513039 T1 ATE513039 T1 AT E513039T1
Authority
AT
Austria
Prior art keywords
nucleic acid
isolation method
acid isolation
reagent set
corresponding reagent
Prior art date
Application number
AT00989419T
Other languages
English (en)
Inventor
Gerard Gundling
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23869685&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE513039(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Abbott Lab filed Critical Abbott Lab
Application granted granted Critical
Publication of ATE513039T1 publication Critical patent/ATE513039T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013—Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Saccharide Compounds (AREA)
AT00989419T 1999-12-22 2000-12-21 Nukleinsäureisolationsmethode und entsprechender reagentiensatz dafür ATE513039T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/470,944 US6936414B2 (en) 1999-12-22 1999-12-22 Nucleic acid isolation method and kit
PCT/US2000/034997 WO2001046404A1 (en) 1999-12-22 2000-12-21 Nucleic acid isolation method and kit

Publications (1)

Publication Number Publication Date
ATE513039T1 true ATE513039T1 (de) 2011-07-15

Family

ID=23869685

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00989419T ATE513039T1 (de) 1999-12-22 2000-12-21 Nukleinsäureisolationsmethode und entsprechender reagentiensatz dafür

Country Status (7)

Country Link
US (1) US6936414B2 (de)
EP (1) EP1240320B1 (de)
JP (3) JP2004500067A (de)
AT (1) ATE513039T1 (de)
CA (1) CA2392802C (de)
ES (1) ES2366341T3 (de)
WO (1) WO2001046404A1 (de)

Families Citing this family (94)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7569342B2 (en) 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
DE19836559A1 (de) 1998-08-12 2000-03-23 Antigen Gmbh Gefäß zur Entnahme von Blut
EP1422298B1 (de) * 1999-07-09 2010-01-27 Gen-Probe Incorporated HIV-1 Detektion mittels Nukleinsäureamplifizierung
US6936414B2 (en) * 1999-12-22 2005-08-30 Abbott Laboratories Nucleic acid isolation method and kit
DE10006662A1 (de) 2000-02-15 2001-08-23 Antigen Produktions Gmbh Gefäß zur Nukleinsäureanalytik
US6692700B2 (en) 2001-02-14 2004-02-17 Handylab, Inc. Heat-reduction methods and systems related to microfluidic devices
WO2004060278A2 (en) 2002-12-06 2004-07-22 Isis Pharmaceuticals, Inc. Methods for rapid identification of pathogens in humans and animals
US20040121311A1 (en) 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in livestock
US7666588B2 (en) 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
US7226739B2 (en) 2001-03-02 2007-06-05 Isis Pharmaceuticals, Inc Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations
US20030027135A1 (en) 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
US7217510B2 (en) 2001-06-26 2007-05-15 Isis Pharmaceuticals, Inc. Methods for providing bacterial bioagent characterizing information
US8073627B2 (en) 2001-06-26 2011-12-06 Ibis Biosciences, Inc. System for indentification of pathogens
JP4852807B2 (ja) * 2001-08-21 2012-01-11 Ｊｓｒ株式会社 ウイルス検出方法
US6852491B2 (en) * 2001-09-04 2005-02-08 Abbott Laboratories Amplification and detection reagents for HIV-1
WO2003097808A2 (en) * 2002-05-17 2003-11-27 Becton, Dickinson And Company Automated system for isolating, amplyifying and detecting a target nucleic acid sequence
DE10231659B4 (de) * 2002-07-12 2006-01-19 Preanalytix Gmbh Zusammensetzung zum Binden von Nukleinsäure an eine Festphase
US7214484B2 (en) * 2002-12-17 2007-05-08 Sigma-Aldrich Co. Compositions and methods for nucleic acid extraction from biological samples
US7601491B2 (en) * 2003-02-06 2009-10-13 Becton, Dickinson And Company Pretreatment method for extraction of nucleic acid from biological samples and kits therefor
US20040157219A1 (en) * 2003-02-06 2004-08-12 Jianrong Lou Chemical treatment of biological samples for nucleic acid extraction and kits therefor
US8057993B2 (en) 2003-04-26 2011-11-15 Ibis Biosciences, Inc. Methods for identification of coronaviruses
US7964343B2 (en) 2003-05-13 2011-06-21 Ibis Biosciences, Inc. Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8158354B2 (en) 2003-05-13 2012-04-17 Ibis Biosciences, Inc. Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
WO2004108925A1 (en) * 2003-06-04 2004-12-16 Qiagen As Method for sequentially isolating dna and rna from the same nucleic acid-containing sample
US7731906B2 (en) 2003-07-31 2010-06-08 Handylab, Inc. Processing particle-containing samples
US20120122103A1 (en) 2003-09-11 2012-05-17 Rangarajan Sampath Compositions for use in identification of bacteria
US8097416B2 (en) 2003-09-11 2012-01-17 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US8546082B2 (en) 2003-09-11 2013-10-01 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US8163895B2 (en) 2003-12-05 2012-04-24 Ibis Biosciences, Inc. Compositions for use in identification of orthopoxviruses
DE10358137A1 (de) * 2003-12-12 2005-07-07 Merck Patent Gmbh Verfahren und Kit zur Isolierung von RNA
US7666592B2 (en) 2004-02-18 2010-02-23 Ibis Biosciences, Inc. Methods for concurrent identification and quantification of an unknown bioagent
WO2005093065A1 (en) * 2004-03-16 2005-10-06 Roche Diagnostics Gmbh Improved method of isolating nucleic acids
CA2502549C (en) * 2004-04-23 2016-02-16 Becton, Dickinson And Company Use of an extraction control in a method of extracting nucleic acids
AU2011250756B2 (en) * 2004-05-03 2014-10-23 Handylab, Inc. Processing polynucleotide-containing samples
US8852862B2 (en) * 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
CA2567839C (en) 2004-05-24 2011-06-28 Isis Pharmaceuticals, Inc. Mass spectrometry with selective ion filtration by digital thresholding
US20050266411A1 (en) 2004-05-25 2005-12-01 Hofstadler Steven A Methods for rapid forensic analysis of mitochondrial DNA
US7811753B2 (en) 2004-07-14 2010-10-12 Ibis Biosciences, Inc. Methods for repairing degraded DNA
US20060024776A1 (en) * 2004-08-02 2006-02-02 Mcmillian Ray Magnetic particle capture of whole intact organisms from clinical samples
AU2005271687A1 (en) * 2004-08-03 2006-02-16 Becton, Dickinson And Company Use of magnetic material to fractionate samples
CA2600184A1 (en) 2005-03-03 2006-09-08 Isis Pharmaceuticals, Inc. Compositions for use in identification of adventitious viruses
US8084207B2 (en) 2005-03-03 2011-12-27 Ibis Bioscience, Inc. Compositions for use in identification of papillomavirus
US20060223071A1 (en) * 2005-04-01 2006-10-05 Wisniewski Michele E Methods, compositions, and kits for detecting nucleic acids in a single vessel
DE502006008765D1 (de) 2005-06-23 2011-03-03 Siemens Healthcare Diagnostics Magnetpartikel mit einer geschlossenen, ultradünnen silikaschicht, verfahren zu deren herstellung und verwendung
AU2006272776B2 (en) 2005-07-21 2012-01-19 Ibis Biosciences, Inc. Methods for rapid identification and quantitation of nucleic acid variants
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US7998708B2 (en) 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
EP3088083B1 (de) 2006-03-24 2018-08-01 Handylab, Inc. Methode zur durchführung von pcr mittels einer kartusche mit mehreren bahnen
US8883490B2 (en) 2006-03-24 2014-11-11 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
KR100754399B1 (ko) * 2006-04-05 2007-08-31 삼성전자주식회사 단일 챔버를 이용한 세포 파괴 및 핵산의 정제 방법 및장치
US10131935B2 (en) * 2006-07-11 2018-11-20 Aj Innuscreen Gmbh Method for parallel isolation of viral nucleic acids
KR100813265B1 (ko) 2006-08-21 2008-03-13 삼성전자주식회사 비평면 형상의 고체 지지체를 이용하여 미생물로부터핵산을 증폭하는 방법
KR100813264B1 (ko) 2006-08-21 2008-03-13 삼성전자주식회사 비평면 형상의 고체 지지체를 이용하여 미생물로부터핵산을 증폭하는 방법
US8273310B2 (en) * 2006-09-05 2012-09-25 Samsung Electronics Co., Ltd. Centrifugal force-based microfluidic device for nucleic acid extraction and microfluidic system including the microfluidic device
EP2064332B1 (de) 2006-09-14 2012-07-18 Ibis Biosciences, Inc. Gezielte gesamtgenomamplifizierung zur identifizierung von krankheitserregern
US8709787B2 (en) 2006-11-14 2014-04-29 Handylab, Inc. Microfluidic cartridge and method of using same
WO2008104002A2 (en) 2007-02-23 2008-08-28 Ibis Biosciences, Inc. Methods for rapid forensic dna analysis
US20100190240A1 (en) * 2007-03-21 2010-07-29 Ibis Biosciences, Inc. Reagents for nucleic acid purification
WO2008151023A2 (en) 2007-06-01 2008-12-11 Ibis Biosciences, Inc. Methods and compositions for multiple displacement amplification of nucleic acids
JP5651011B2 (ja) 2007-07-13 2015-01-07 ハンディーラブ インコーポレイテッド ポリヌクレオチド捕捉材料およびその使用方法
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
WO2009099854A1 (en) * 2008-02-01 2009-08-13 Siemens Healthcare Diagnostics Inc. Urine transport medium
USD787087S1 (en) 2008-07-14 2017-05-16 Handylab, Inc. Housing
JP4963118B2 (ja) * 2008-08-21 2012-06-27 山梨県 動物繊維における銀染色方法、２−メルカプトエタンスルホン酸塩水溶液を用いた銀染色の制御方法、及びこれらの方法を適用した動物繊維
US8550694B2 (en) 2008-09-16 2013-10-08 Ibis Biosciences, Inc. Mixing cartridges, mixing stations, and related kits, systems, and methods
US8148163B2 (en) 2008-09-16 2012-04-03 Ibis Biosciences, Inc. Sample processing units, systems, and related methods
EP2344893B1 (de) 2008-09-16 2014-10-15 Ibis Biosciences, Inc. Mikroplatten-handhabungssysteme und verfahren
US8158936B2 (en) 2009-02-12 2012-04-17 Ibis Biosciences, Inc. Ionization probe assemblies
WO2011008972A1 (en) 2009-07-17 2011-01-20 Ibis Biosciences, Inc. Systems for bioagent identification
WO2011008971A1 (en) 2009-07-17 2011-01-20 Ibis Biosciences, Inc. Lift and mount apparatus
ES2628739T3 (es) 2009-10-15 2017-08-03 Ibis Biosciences, Inc. Amplificación por desplazamiento múltiple
TWI407994B (zh) 2009-10-22 2013-09-11 Ind Tech Res Inst 分離核酸的方法、試劑及套組
GB201020095D0 (en) 2010-11-26 2011-01-12 Invitrogen Dynal As Nucleic acid preparation method
ES2617599T3 (es) 2011-04-15 2017-06-19 Becton, Dickinson And Company Termociclador microfluídico de exploración en tiempo real y métodos para termociclado sincronizado y detección óptica de exploración
USD692162S1 (en) 2011-09-30 2013-10-22 Becton, Dickinson And Company Single piece reagent holder
KR102121853B1 (ko) 2011-09-30 2020-06-12 벡톤 디킨슨 앤드 컴퍼니 일체화된 시약 스트립
EP2773892B1 (de) 2011-11-04 2020-10-07 Handylab, Inc. Vorrichtung zur vorbereitung von polynukleotidproben
BR112014018995B1 (pt) 2012-02-03 2021-01-19 Becton, Dickson And Company sistemas para executar ensaio automatizado
BR112017000581B1 (pt) 2014-07-11 2020-12-01 Abbott Molecular Inc. método automatizado para detectar ácidos nucleicos de hiv-1 em uma amostra de sangue
FR3031063B1 (fr) 2014-12-30 2017-02-10 Biomerieux Sa Complexe multicouches, procede de fabrication et utilisation du complexe
ES2902125T3 (es) * 2015-07-14 2022-03-25 Abbott Molecular Inc Purificación de ácidos nucleicos utilizando óxidos de cobre-titanio u óxidos de magnesio-titanio
CN108350448A (zh) * 2015-09-10 2018-07-31 株式会社钟化 从含有核酸的样品中分离核酸的方法及用于该方法的装置
WO2017044710A1 (en) * 2015-09-11 2017-03-16 Corning Incorporated Compositions and methods for nucleic acid purification from blood samples
JP2017097681A (ja) 2015-11-26 2017-06-01 マツダ株式会社 標識認識システム
US20180135040A1 (en) 2016-02-16 2018-05-17 Life Magnetics, Inc. Methods for separating nucleic acids with graphene coated magnetic beads
JP7151725B2 (ja) 2017-12-28 2022-10-12 ソニーグループ株式会社 制御装置、および制御方法、プログラム、並びに移動体
WO2022232550A1 (en) 2021-04-29 2022-11-03 Abbott Laboratories Systems and methods for pooling samples for high-throughput analysis

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5482834A (en) * 1982-05-17 1996-01-09 Hahnemann University Evaluation of nucleic acids in a biological sample hybridization in a solution of chaotrophic salt solubilized cells
US5750338A (en) * 1986-10-23 1998-05-12 Amoco Corporation Target and background capture methods with amplification for affinity assays
GB2221466A (en) 1988-03-09 1990-02-07 Aluminum Co Of America Biologically reactive particles with biological, therapeutic and chromatographic applications
US5234809A (en) * 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
CA2011929A1 (en) 1989-04-03 1990-10-03 Rex M. Bitner Metal oxide supports for nucleic acids
US5010183A (en) * 1989-07-07 1991-04-23 Macfarlane Donald E Process for purifying DNA and RNA using cationic detergents
US5128247A (en) * 1989-08-14 1992-07-07 Board Of Regents, The University Of Texas System Methods for isolation of nucleic acids from eukaryotic and prokaryotic sources
GB9003253D0 (en) 1990-02-13 1990-04-11 Amersham Int Plc Precipitating polymers
US5523231A (en) * 1990-02-13 1996-06-04 Amersham International Plc Method to isolate macromolecules using magnetically attractable beads which do not specifically bind the macromolecules
AU1978692A (en) * 1991-04-12 1992-11-17 Minnesota Mining And Manufacturing Company Purification of nucleic acids using metal oxide supports
CA2067711C (en) * 1991-05-03 2000-08-08 Daniel Lee Woodard Solid phase extraction purification of dna
US5300635A (en) * 1993-02-01 1994-04-05 University Of Iowa Research Foundation Quaternary amine surfactants and methods of using same in isolation of nucleic acids
DE4321904B4 (de) * 1993-07-01 2013-05-16 Qiagen Gmbh Verfahren zur chromatographischen Reinigung und Trennung von Nucleinsäuregemischen
GB9411572D0 (en) 1994-06-09 1994-08-03 Amersham Int Plc Magnetic bead precipitation method
US5705628A (en) 1994-09-20 1998-01-06 Whitehead Institute For Biomedical Research DNA purification and isolation using magnetic particles
GB9425138D0 (en) 1994-12-12 1995-02-08 Dynal As Isolation of nucleic acid
DE19520398B4 (de) 1995-06-08 2009-04-16 Roche Diagnostics Gmbh Magnetisches Pigment
JP2965131B2 (ja) * 1995-07-07 1999-10-18 東洋紡績株式会社 核酸結合用磁性担体およびそれを用いる核酸単離方法
US5945515A (en) * 1995-07-31 1999-08-31 Chomczynski; Piotr Product and process for isolating DNA, RNA and proteins
US5973137A (en) * 1996-02-13 1999-10-26 Gentra Systems, Inc. Low pH RNA isolation reagents, method, and kit
EP0818461B1 (de) 1996-07-12 2005-09-28 Toyo Boseki Kabushiki Kaisha Verfahren zur Isolierung von Ribonucleinsäuren.
US6027945A (en) 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
US5958677A (en) * 1997-07-28 1999-09-28 The New York Blood Center, Inc. Method for purifying viral nucleic acids
EP0897978A3 (de) * 1997-08-22 2001-10-17 Becton, Dickinson and Company Zirkoniumoxyd und verwandten Verbindungen zur Reinigung von Nukleinsäuren
JP3812696B2 (ja) * 1997-11-17 2006-08-23 東洋紡績株式会社 リボ核酸の抽出方法
JP3856174B2 (ja) * 1997-12-11 2006-12-13 東洋紡績株式会社 植物ｄｎａの抽出精製方法
JPH11191509A (ja) * 1997-12-25 1999-07-13 Jsr Corp 磁性粒子、製造方法および診断薬
JPH11262387A (ja) * 1998-03-16 1999-09-28 Toyobo Co Ltd 核酸結合性磁性担体およびそれを用いた核酸単離方法
JP3587052B2 (ja) * 1998-03-25 2004-11-10 株式会社日立製作所 生体試料前処理方法及びその装置
US5973138A (en) * 1998-10-30 1999-10-26 Becton Dickinson And Company Method for purification and manipulation of nucleic acids using paramagnetic particles
US6936414B2 (en) * 1999-12-22 2005-08-30 Abbott Laboratories Nucleic acid isolation method and kit

Also Published As

Publication number Publication date
JP2016198093A (ja) 2016-12-01
EP1240320B1 (de) 2011-06-15
CA2392802C (en) 2011-11-15
WO2001046404A1 (en) 2001-06-28
ES2366341T3 (es) 2011-10-19
JP6364039B2 (ja) 2018-07-25
JP2014012011A (ja) 2014-01-23
EP1240320A1 (de) 2002-09-18
JP2004500067A (ja) 2004-01-08
US6936414B2 (en) 2005-08-30
US20020068821A1 (en) 2002-06-06
CA2392802A1 (en) 2001-06-28

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