ATE389645T1 - Verfahren zur herstellung von citalopram - Google Patents

Verfahren zur herstellung von citalopram

Info

Publication number: ATE389645T1
Authority: AT; Austria
Prior art keywords: producing citalopram; citalopram; producing
Prior art date: 2000-05-12

Application number

AT01931469T

Other languages

English (en)

Inventor

Hans Petersen

Robert Dancer

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-05-12

Filing date

2001-05-10

Publication date

2008-04-15

2001-05-10 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2008-04-15 Application granted granted Critical

2008-04-15 Publication of ATE389645T1 publication Critical patent/ATE389645T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pain & Pain Management (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Psychiatry (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Steroid Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Furan Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

AT01931469T 2000-05-12 2001-05-10 Verfahren zur herstellung von citalopram ATE389645T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DKPA200000783		2000-05-12

Publications (1)

Publication Number	Publication Date
ATE389645T1 true ATE389645T1 (de)	2008-04-15

Family

ID=8159493

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01931469T ATE389645T1 (de)	2000-05-12	2001-05-10	Verfahren zur herstellung von citalopram

Country Status (30)

Country	Link
US (1)	US6660873B2 (de)
EP (1)	EP1296970B1 (de)
JP (1)	JP2003532721A (de)
CN (1)	CN100422166C (de)
AR (1)	AR032455A1 (de)
AT (1)	ATE389645T1 (de)
AU (2)	AU2001258239B2 (de)
BG (1)	BG65820B1 (de)
BR (1)	BR0110996A (de)
CA (1)	CA2408292C (de)
CZ (1)	CZ20024065A3 (de)
DE (1)	DE60133280T2 (de)
DK (1)	DK1296970T3 (de)
EA (1)	EA005674B1 (de)
ES (1)	ES2301541T3 (de)
HK (1)	HK1056171A1 (de)
HR (1)	HRP20020881A2 (de)
HU (1)	HUP0301942A2 (de)
IL (2)	IL152645A0 (de)
IS (1)	IS2586B (de)
MX (1)	MXPA02011125A (de)
NO (1)	NO327963B1 (de)
NZ (1)	NZ522475A (de)
PL (1)	PL358144A1 (de)
PT (1)	PT1296970E (de)
SI (1)	SI1296970T1 (de)
SK (1)	SK287035B6 (de)
UA (1)	UA72039C2 (de)
WO (1)	WO2001085712A1 (de)
ZA (1)	ZA200208973B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE69907037T3 (de)	1999-04-14	2010-02-18	H. Lundbeck A/S	Verfahren zur herstellung von citalopram
US6310222B1 (en) *	1999-11-01	2001-10-30	Sumika Fine Chemicals Co., Ltd.	Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
US6433196B1 (en) *	2000-02-17	2002-08-13	Sumika Fine Chemicals Co., Ltd.	Production method of citalopram, intermediate therefor and production method of the intermediate
IES20010157A2 (en)	2000-03-03	2002-03-06	Lundbeck & Co As H	Method for the preparation of citalopram
IL151566A0 (en)	2000-03-13	2003-04-10	Lundbeck & Co As H	Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
IES20010206A2 (en)	2000-03-13	2002-03-06	Lundbeck & Co As H	Method for the preparation of citalopram
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IN192057B (de) *	2001-07-19	2004-02-14	Ranbaxy Lab Ltd
US20050154052A1 (en) *	2003-03-24	2005-07-14	Hetero Drugs Limited	Novel crystalline forms of (s)-citalopram oxalate
EP1678122A4 (de) *	2003-10-28	2007-05-23	Wockhardt Ltd	Verbessertes verfahren zur herstellung von citalopram-hydrobromid
US20050143350A1 (en) *	2003-11-19	2005-06-30	Seed John C.	Combination drug therapy to treat obesity
EP1797060A2 (de)	2004-08-23	2007-06-20	Sun Pharmaceutical Industries Limited	Verfahren zur herstellung von citalopram und enantiomeren

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1143702A (de)	1965-03-18
GB1526331A (en) *	1976-01-14	1978-09-27	Kefalas As	Phthalanes
GB8419963D0 (en)	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
GB8814057D0 (en)	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
US5296507A (en)	1990-09-06	1994-03-22	H.Lundbeck A/S	Treatment of cerbrovascular disorders
DE19626659A1 (de)	1996-07-03	1998-01-08	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de)	1996-07-10	1998-01-15	Basf Ag	Verfahren zur Herstellung von Phthaliden
NZ501737A (en)	1997-07-08	2001-10-26	H	Method for the preparation of citalopram using Grignard reagent 4-halogen-fluorophenyl and 3-halogen-N,N-dimethyl-propylamine
UA62985C2 (en) *	1997-11-10	2004-01-15	Lunnbeck As H	A method for the preparation of citalopram
DE1042310T1 (de) *	1997-11-11	2001-04-19	Lundbeck & Co As H	Verfahren zur herstellung von citaloprame
PL199423B1 (pl)	1998-10-20	2008-09-30	Lundbeck & Co As H	Sposób wytwarzania citalopramu
PT1140886E (pt)	1998-12-23	2003-08-29	Lundbeck & Co As H	Metodo para a preparacao de 5- cianoftalida
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
DE69907037T3 (de)	1999-04-14	2010-02-18	H. Lundbeck A/S	Verfahren zur herstellung von citalopram
ITMI991581A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991486A1 (it)	1999-07-06	2001-01-06	Vis Farmaceutici S P A	Processo per la sintesi di citalopram
CH692421A5 (de)	1999-10-25	2002-06-14	Lundbeck & Co As H	Verfahren zur Herstellung von Citalopram.
AR026063A1 (es)	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
US6310222B1 (en)	1999-11-01	2001-10-30	Sumika Fine Chemicals Co., Ltd.	Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
IL150335A0 (en)	1999-12-28	2002-12-01	Lundbeck & Co As H	Method for the preparation of citalopram
CZ20022627A3 (cs)	1999-12-30	2002-10-16	H. Lundbeck A/S	Způsob výroby citalopramu
DK1254129T3 (da)	2000-01-14	2004-03-29	Lundbeck & Co As H	Fremgangsmåde til fremstilling af 5-cyanophthalid
IT1317729B1 (it)	2000-01-18	2003-07-15	Norpharma S P A	Procedimento per la preparazione della 5-carbossiftalide.
US6433196B1 (en)	2000-02-17	2002-08-13	Sumika Fine Chemicals Co., Ltd.	Production method of citalopram, intermediate therefor and production method of the intermediate
IES20010143A2 (en)	2000-02-24	2001-07-25	Lundbeck & Co As H	Method for the preparation of citalopram
FR2805812A1 (fr)	2000-02-24	2001-09-07	Lundbeck & Co As H	Procede de preparation du citalopram
IES20010157A2 (en)	2000-03-03	2002-03-06	Lundbeck & Co As H	Method for the preparation of citalopram
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
GB2357762B (en)	2000-03-13	2002-01-30	Lundbeck & Co As H	Crystalline base of citalopram
HUP0300274A2 (hu)	2000-03-13	2003-06-28	H. Lundbeck A/S	Eljárás citalopram előállítására
IES20010206A2 (en)	2000-03-13	2002-03-06	Lundbeck & Co As H	Method for the preparation of citalopram
IL151566A0 (en)	2000-03-13	2003-04-10	Lundbeck & Co As H	Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
SK14512002A3 (sk)	2000-03-14	2003-03-04	H. Lundbeck A/S	Spôsob výroby citalopramu, medziprodukt a citalopram výrobený týmto spôsobom
BR0109180A (pt)	2000-03-16	2003-05-27	Lundbeck & Co As H	Método para a preparação de 5-ciano-1-(4-fluorofenil) -1,3- diidroisobenzofuranos e composição farmacêutica de antidepressivo
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
CA2383963A1 (en)	2000-07-06	2002-01-17	Eva Bolzonella	Method for the preparation of citalopram
FI20011622L (fi)	2000-08-18	2002-02-19	Lundbeck & Co As H	Menetelmä sitalopraamin valmistamiseksi
TR200201166T1 (tr)	2000-12-22	2002-10-21	H.Lundbecks A/S	Saf sitalopram hazırlanması için yöntem
EP1181272B1 (de)	2000-12-28	2002-08-28	H. Lundbeck A/S	Verfahren zur herstellung von reinem citalopram

2001
- 2001-05-07 AR ARP010102152A patent/AR032455A1/es active IP Right Grant
- 2001-05-10 NZ NZ522475A patent/NZ522475A/en unknown
- 2001-05-10 CZ CZ20024065A patent/CZ20024065A3/cs unknown
- 2001-05-10 ES ES01931469T patent/ES2301541T3/es not_active Expired - Lifetime
- 2001-05-10 CN CNB018125859A patent/CN100422166C/zh not_active Expired - Fee Related
- 2001-05-10 EA EA200201211A patent/EA005674B1/ru not_active IP Right Cessation
- 2001-05-10 WO PCT/DK2001/000333 patent/WO2001085712A1/en active IP Right Grant
- 2001-05-10 PT PT01931469T patent/PT1296970E/pt unknown
- 2001-05-10 DE DE60133280T patent/DE60133280T2/de not_active Expired - Fee Related
- 2001-05-10 JP JP2001582313A patent/JP2003532721A/ja not_active Withdrawn
- 2001-05-10 MX MXPA02011125A patent/MXPA02011125A/es active IP Right Grant
- 2001-05-10 AU AU2001258239A patent/AU2001258239B2/en not_active Ceased
- 2001-05-10 SK SK1754-2002A patent/SK287035B6/sk not_active IP Right Cessation
- 2001-05-10 PL PL01358144A patent/PL358144A1/xx unknown
- 2001-05-10 EP EP01931469A patent/EP1296970B1/de not_active Expired - Lifetime
- 2001-05-10 BR BR0110996-0A patent/BR0110996A/pt not_active Application Discontinuation
- 2001-05-10 HU HU0301942A patent/HUP0301942A2/hu unknown
- 2001-05-10 AU AU5823901A patent/AU5823901A/xx active Pending
- 2001-05-10 DK DK01931469T patent/DK1296970T3/da active
- 2001-05-10 IL IL15264501A patent/IL152645A0/xx unknown
- 2001-05-10 SI SI200130831T patent/SI1296970T1/sl unknown
- 2001-05-10 CA CA002408292A patent/CA2408292C/en not_active Expired - Fee Related
- 2001-05-10 AT AT01931469T patent/ATE389645T1/de not_active IP Right Cessation
- 2001-10-05 UA UA2002118821A patent/UA72039C2/uk unknown
2002
- 2002-10-31 IS IS6605A patent/IS2586B/is unknown
- 2002-11-04 IL IL152645A patent/IL152645A/en not_active IP Right Cessation
- 2002-11-05 ZA ZA200208973A patent/ZA200208973B/en unknown
- 2002-11-08 HR HRP20020881 patent/HRP20020881A2/hr not_active Application Discontinuation
- 2002-11-08 US US10/291,174 patent/US6660873B2/en not_active Expired - Fee Related
- 2002-11-12 NO NO20025423A patent/NO327963B1/no not_active IP Right Cessation
- 2002-12-03 BG BG107349A patent/BG65820B1/bg unknown
2003
- 2003-11-20 HK HK03108460.1A patent/HK1056171A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO20025423L (no)	2002-11-12
PT1296970E (pt)	2008-06-11
EA200201211A1 (ru)	2003-04-24
US6660873B2 (en)	2003-12-09
MXPA02011125A (es)	2003-03-10
EA005674B1 (ru)	2005-04-28
DK1296970T3 (da)	2008-07-14
AR032455A1 (es)	2003-11-12
DE60133280T2 (de)	2009-04-16
CZ20024065A3 (cs)	2003-03-12
US20030134895A1 (en)	2003-07-17
EP1296970A1 (de)	2003-04-02
SK287035B6 (sk)	2009-10-07
BG107349A (bg)	2003-09-30
NO327963B1 (no)	2009-10-26
HK1056171A1 (en)	2004-02-06
IL152645A (en)	2009-12-24
ES2301541T3 (es)	2008-07-01
SI1296970T1 (sl)	2008-08-31
CN100422166C (zh)	2008-10-01
BG65820B1 (bg)	2010-01-29
EP1296970B1 (de)	2008-03-19
ZA200208973B (en)	2003-11-05
NO20025423D0 (no)	2002-11-12
AU2001258239B2 (en)	2005-12-08
IL152645A0 (en)	2003-06-24
IS2586B (is)	2010-02-15
BR0110996A (pt)	2003-03-18
NZ522475A (en)	2004-09-24
HUP0301942A2 (hu)	2003-09-29
JP2003532721A (ja)	2003-11-05
WO2001085712A1 (en)	2001-11-15
CN1441795A (zh)	2003-09-10
CA2408292C (en)	2009-11-10
CA2408292A1 (en)	2001-11-15
PL358144A1 (en)	2004-08-09
SK17542002A3 (sk)	2003-04-01
IS6605A (is)	2002-10-31
HRP20020881A2 (en)	2004-12-31
DE60133280D1 (de)	2008-04-30
UA72039C2 (en)	2005-01-17
AU5823901A (en)	2001-11-20

Publication	Publication Date	Title
DE69907037T2 (de)	2004-01-29	Verfahren zur herstellung von citalopram
DE69900891D1 (de)	2002-03-21	Verfahren zur herstellung von citalopram
ATE235478T1 (de)	2003-04-15	Verfahren zur herstellung von citalopram
ATE222899T1 (de)	2002-09-15	Verfahren zur herstellung von reinem citalopram
ATE230738T1 (de)	2003-01-15	Verfahren zur herstellung von citalopram
ATE281448T1 (de)	2004-11-15	Verfahren zur herstellung von citalopram
ATE386736T1 (de)	2008-03-15	Verfahren zur herstellung von benzimidazol-2-yl - chinolinonderivaten
AT7110U9 (de)	2004-11-25	Verfahren zur herstellung von amlodipinmaleat
ATE222900T1 (de)	2002-09-15	Verfahren zur herstellung von 5-cyanophthalid
ATE277920T1 (de)	2004-10-15	Verfahren zur vorbereitung von reinem citalopram
ATE331804T1 (de)	2006-07-15	Verfahren zur herstellung von ansamitocin
DE50102444D1 (de)	2004-07-01	Verfahren zur herstellung von isocyanatoorganosilanen
ATE316518T1 (de)	2006-02-15	Verfahren zur herstellung von (r)-2-alkyl-3- phenyl-1-propanolen
DE60103173D1 (de)	2004-06-09	Verfahren zur herstellung von 3-amino-2-chlor-4-methylpyridin
DE50111560D1 (de)	2007-01-11	Verfahren zur herstellung von guerbetalkoholen
ATE389645T1 (de)	2008-04-15	Verfahren zur herstellung von citalopram
DE60003264D1 (de)	2003-07-17	Verfahren zur herstellung von glycerylethern
DE50006772D1 (de)	2004-07-15	Verfahren zur herstellung von oxindolen
ATE277032T1 (de)	2004-10-15	Verfahren zur herstellung von citalopram
DE60105991D1 (de)	2004-11-04	Verfahren zur herstellung von 6-aminocapronamid
ATE282031T1 (de)	2004-11-15	Verfahren zur herstellung von citalopram
DE50001895D1 (de)	2003-05-28	Verfahren zur herstellung von phosphonomethylglycin
ATE232845T1 (de)	2003-03-15	Verfahren zur herstellung von cyclopropenen
ATE325810T1 (de)	2006-06-15	Verfahren zur herstellung von acetylamidiniophenylalanyl-cyclohexylglycyl- pyridylalaninamiden
ATE327995T1 (de)	2006-06-15	Verfahren zur herstellung von camptothectin

Legal Events

Date	Code	Title	Description
2008-09-15	UEP	Publication of translation of european patent specification	Ref document number: 1296970 Country of ref document: EP
2011-02-15	REN	Ceased due to non-payment of the annual fee

Date

Code

Title

Description

2008-09-15

UEP

Publication of translation of european patent specification

Ref document number: 1296970

Country of ref document: EP

2011-02-15

REN

Ceased due to non-payment of the annual fee