ATE277032T1 - Verfahren zur herstellung von citalopram - Google Patents

Verfahren zur herstellung von citalopram

Info

Publication number: ATE277032T1
Authority: AT; Austria
Prior art keywords: producing citalopram; citalopram; producing
Prior art date: 1999-10-25

Application number

AT99950511T

Other languages

English (en)

Inventor

Michael Harold Rock

Hans Petersen

Peter Ellegaard

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-10-25

Filing date

1999-10-25

Publication date

2004-10-15

1999-10-25 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

1999-10-25 Priority claimed from PCT/DK1999/000581 external-priority patent/WO2000012044A2/en

2004-10-15 Application granted granted Critical

2004-10-15 Publication of ATE277032T1 publication Critical patent/ATE277032T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/56—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and doubly-bound oxygen atoms bound to the carbon skeleton

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Epidemiology (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)

AT99950511T 1999-10-25 1999-10-25 Verfahren zur herstellung von citalopram ATE277032T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/DK1999/000581 WO2000012044A2 (en)	1999-10-25	1999-10-25	Method for the preparation of citalopram

Publications (1)

Publication Number	Publication Date
ATE277032T1 true ATE277032T1 (de)	2004-10-15

Family

ID=8157164

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT99950511T ATE277032T1 (de)	1999-10-25	1999-10-25	Verfahren zur herstellung von citalopram
AT02028326T ATE355268T1 (de)	1999-10-25	1999-10-25	Verfahren zur herstellung von citalopram

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT02028326T ATE355268T1 (de)	1999-10-25	1999-10-25	Verfahren zur herstellung von citalopram

Country Status (25)

Country	Link
US (1)	US6566540B2 (de)
EP (1)	EP1298124B1 (de)
KR (1)	KR100505820B1 (de)
AR (1)	AR024518A1 (de)
AT (2)	ATE277032T1 (de)
CA (1)	CA2291133C (de)
CY (1)	CY1107635T1 (de)
CZ (1)	CZ292894B6 (de)
DE (3)	DE19983836C1 (de)
DK (2)	DK1228056T3 (de)
EA (1)	EA002801B1 (de)
ES (1)	ES2282365T3 (de)
HK (1)	HK1043129B (de)
HR (1)	HRP20020344B1 (de)
HU (1)	HUP0200169A3 (de)
IL (3)	IL143875A0 (de)
IS (1)	IS2260B (de)
NO (1)	NO20071311L (de)
NZ (1)	NZ512406A (de)
PL (1)	PL201056B1 (de)
PT (2)	PT1228056E (de)
SI (2)	SI1228056T1 (de)
SK (1)	SK287140B6 (de)
TR (1)	TR200401456T1 (de)
UA (1)	UA72238C2 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AR034612A1 (es) *	2001-06-25	2004-03-03	Lundbeck & Co As H	Proceso para la preparacion del citalopram racemico y/o del s- o r-citalopram mediante la separacion de una mezcla de r- y s-citalopram
AR040970A1 (es) *	2002-08-12	2005-04-27	Lundbeck & Co As H	Metodo para la separacion de intermediarios que pueden ser utilizados para la preparacion de escitalopram
CA2511142A1 (en) *	2002-12-23	2004-07-08	H. Lundbeck A/S	Escitalopram hydrobromide and a method for the preparation thereof
US20050137255A1 (en) *	2002-12-23	2005-06-23	H. Lundbeck A/S	Crystalline escitalopram hydrobromide and methods for preparing the same
WO2004085416A1 (en) *	2003-03-24	2004-10-07	Hetero Drugs Limited	Novel crystalline forms of (s)-citalopram oxalate
US20050196453A1 (en) *	2004-03-05	2005-09-08	H. Lundbeck A/S	Crystalline composition containing escitalopram
JP2009511606A (ja) *	2005-10-14	2009-03-19	ハー・ルンドベック・アクチエゼルスカベット	エスシタロプラムおよびブプロピオンの低用量の併用を用いる中枢神経系障害の治療方法
AU2006304889A1 (en) *	2005-10-14	2007-04-26	H. Lundbeck A/S	Stable pharmaceutical formulations containing escitalopram and bupropion
KR101612563B1 (ko) *	2007-08-03	2016-04-14	리히터 게데온 닐트.	도파민 수용체 리간드를 함유하는 약학적 조성물 및 도파민 수용체 리간드를 사용한 치료 방법

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1143702A (de)	1965-03-18
GB1526331A (en)	1976-01-14	1978-09-27	Kefalas As	Phthalanes
GB8419963D0 (en) *	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
GB8814057D0 (en) *	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
DE3926765A1 (de)	1989-08-12	1991-02-14	Hoechst Ag	Verfahren zur verminderung von primaerem und sekundaerem amin in einem tertiaeren amin
US5296507A (en)	1990-09-06	1994-03-22	H.Lundbeck A/S	Treatment of cerbrovascular disorders
DE19626659A1 (de)	1996-07-03	1998-01-08	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de)	1996-07-10	1998-01-15	Basf Ag	Verfahren zur Herstellung von Phthaliden
DK1015416T3 (da) *	1997-07-08	2001-11-05	Lundbeck & Co As H	Fremgangsmåde til fremstilling af citalopram
UA62985C2 (en)	1997-11-10	2004-01-15	Lunnbeck As H	A method for the preparation of citalopram
SK283907B6 (sk) *	1997-11-11	2004-04-06	H. Lundbeck A/S	Spôsob výroby citalopramu a medziprodukty
ES2189502T3 (es)	1998-10-20	2003-07-01	Lundbeck & Co As H	Metodo para la prevencion de citalopram.
KR100454008B1 (ko)	1998-12-23	2004-10-20	하. 룬트벡 아크티에 셀스카브	5-시아노프탈리드의 제조방법
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
SI1173431T2 (sl)	1999-04-14	2009-12-31	Lundbeck & Co As H	Postopek za pripravo citaloprama
ITMI991581A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
US6310222B1 (en)	1999-11-01	2001-10-30	Sumika Fine Chemicals Co., Ltd.	Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
FR2805812A1 (fr)	2000-02-24	2001-09-07	Lundbeck & Co As H	Procede de preparation du citalopram
IES20010143A2 (en)	2000-02-24	2001-07-25	Lundbeck & Co As H	Method for the preparation of citalopram
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
IL144816A (en)	2000-08-18	2005-09-25	Lundbeck & Co As H	Method for the preparation of citalopram
ATE222899T1 (de)	2000-12-28	2002-09-15	Lundbeck & Co As H	Verfahren zur herstellung von reinem citalopram

1999
- 1999-10-25 HU HU0200169A patent/HUP0200169A3/hu unknown
- 1999-10-25 DE DE19983836A patent/DE19983836C1/de not_active Expired - Fee Related
- 1999-10-25 IL IL14387599A patent/IL143875A0/xx active IP Right Grant
- 1999-10-25 HR HR20020344A patent/HRP20020344B1/xx not_active IP Right Cessation
- 1999-10-25 EP EP02028326A patent/EP1298124B1/de not_active Expired - Lifetime
- 1999-10-25 SI SI9930703T patent/SI1228056T1/xx unknown
- 1999-10-25 DE DE69920526T patent/DE69920526T2/de not_active Expired - Lifetime
- 1999-10-25 UA UA2001075224A patent/UA72238C2/uk unknown
- 1999-10-25 KR KR10-2001-7008100A patent/KR100505820B1/ko not_active Expired - Fee Related
- 1999-10-25 NZ NZ512406A patent/NZ512406A/xx not_active IP Right Cessation
- 1999-10-25 DE DE69935355T patent/DE69935355T2/de not_active Expired - Lifetime
- 1999-10-25 TR TR2004/01456T patent/TR200401456T1/xx unknown
- 1999-10-25 PL PL349440A patent/PL201056B1/pl not_active IP Right Cessation
- 1999-10-25 AT AT99950511T patent/ATE277032T1/de active
- 1999-10-25 ES ES02028326T patent/ES2282365T3/es not_active Expired - Lifetime
- 1999-10-25 AT AT02028326T patent/ATE355268T1/de active
- 1999-10-25 CA CA002291133A patent/CA2291133C/en not_active Expired - Fee Related
- 1999-10-25 HK HK02105036.3A patent/HK1043129B/zh not_active IP Right Cessation
- 1999-10-25 DK DK99950511T patent/DK1228056T3/da active
- 1999-10-25 EA EA200100593A patent/EA002801B1/ru not_active IP Right Cessation
- 1999-10-25 SI SI9930960T patent/SI1298124T1/sl unknown
- 1999-10-25 PT PT99950511T patent/PT1228056E/pt unknown
- 1999-10-25 DK DK02028326T patent/DK1298124T3/da active
- 1999-10-25 PT PT02028326T patent/PT1298124E/pt unknown
- 1999-10-25 SK SK50008-2009A patent/SK287140B6/sk not_active IP Right Cessation
- 1999-11-10 AR ARP990105703A patent/AR024518A1/es active IP Right Grant
2001
- 2001-06-15 IS IS5970A patent/IS2260B/is unknown
- 2001-06-20 IL IL143875A patent/IL143875A/en not_active IP Right Cessation
2002
- 2002-05-03 US US10/138,811 patent/US6566540B2/en not_active Expired - Fee Related
- 2002-08-29 CZ CZ20022925A patent/CZ292894B6/cs not_active IP Right Cessation
2006
- 2006-07-18 IL IL176943A patent/IL176943A0/en unknown
2007
- 2007-03-09 NO NO20071311A patent/NO20071311L/no unknown
- 2007-05-21 CY CY20071100690T patent/CY1107635T1/el unknown

Also Published As

Publication number	Publication date
EA002801B1 (ru)	2002-10-31
EP1298124A1 (de)	2003-04-02
HUP0200169A3 (en)	2002-11-28
SI1298124T1 (sl)	2007-08-31
US6566540B2 (en)	2003-05-20
HK1043129B (zh)	2004-10-21
DE69920526T2 (de)	2006-02-23
KR100505820B1 (ko)	2005-08-03
IL143875A0 (en)	2002-04-21
DK1298124T3 (da)	2007-07-09
DE69935355D1 (de)	2007-04-12
PT1298124E (pt)	2007-05-31
US20020177722A1 (en)	2002-11-28
KR20010092799A (ko)	2001-10-27
HK1043129A1 (en)	2002-09-06
CZ292894B6 (cs)	2003-12-17
PL349440A1 (en)	2002-07-29
EA200100593A1 (ru)	2001-10-22
HRP20020344A2 (en)	2004-02-29
UA72238C2 (en)	2005-02-15
IS5970A (is)	2001-06-15
SK287140B6 (sk)	2010-01-07
ATE355268T1 (de)	2006-03-15
CY1107635T1 (el)	2013-04-18
HRP20020344B1 (hr)	2010-10-31
DE69935355T2 (de)	2007-11-08
ES2282365T3 (es)	2007-10-16
TR200401456T1 (tr)	2005-04-21
NO20071311L (no)	2001-08-24
DE19983836C1 (de)	2003-10-23
NZ512406A (en)	2004-01-30
CA2291133A1 (en)	2001-04-25
IL143875A (en)	2008-03-20
PT1228056E (pt)	2005-02-28
AR024518A1 (es)	2002-10-16
DE69920526D1 (de)	2004-10-28
EP1298124B1 (de)	2007-02-28
PL201056B1 (pl)	2009-03-31
IS2260B (is)	2007-06-15
SI1228056T1 (en)	2005-02-28
IL176943A0 (en)	2006-12-10
HUP0200169A2 (en)	2002-06-29
CA2291133C (en)	2003-06-17
DK1228056T3 (da)	2005-01-24

Publication	Publication Date	Title
DE69907037T2 (de)	2004-01-29	Verfahren zur herstellung von citalopram
DE69900891D1 (de)	2002-03-21	Verfahren zur herstellung von citalopram
ATE235478T1 (de)	2003-04-15	Verfahren zur herstellung von citalopram
ATE230738T1 (de)	2003-01-15	Verfahren zur herstellung von citalopram
ATE363476T1 (de)	2007-06-15	Verfahren zur herstellung von furfural
ATE232524T1 (de)	2003-02-15	Verfahren zur herstellung von citalopram
ATE222900T1 (de)	2002-09-15	Verfahren zur herstellung von 5-cyanophthalid
ATE281447T1 (de)	2004-11-15	Verfahren zur herstellung von citalopram
DE60100016D1 (de)	2002-10-02	Verfahren zur herstellung von reinem citalopram
DE69906580D1 (de)	2003-05-08	Verfahren zur herstellung von 5-cyanophthalid
DE69908824D1 (de)	2003-07-17	Verfahren zur herstellung von bisphenol-a
DE60003264D1 (de)	2003-07-17	Verfahren zur herstellung von glycerylethern
ATE389645T1 (de)	2008-04-15	Verfahren zur herstellung von citalopram
DE50006772D1 (de)	2004-07-15	Verfahren zur herstellung von oxindolen
ATE277032T1 (de)	2004-10-15	Verfahren zur herstellung von citalopram
EP1208106A4 (de)	2003-01-02	Verfahren zur herstellung von aminopropyl- oder aminoalkyl-unktionalisierten polyalkyl- oder aryl-siloxanen
ATE282031T1 (de)	2004-11-15	Verfahren zur herstellung von citalopram
DE50001895D1 (de)	2003-05-28	Verfahren zur herstellung von phosphonomethylglycin
DE60004834D1 (de)	2003-10-02	Verfahren zur herstellung von mikrokapseln
ATE233238T1 (de)	2003-03-15	Verfahren zur herstellung von 3-acyl-indolen
DE50002773D1 (de)	2003-08-07	Verfahren zur herstellung von hydroxymethylpyridinen
DE60011427D1 (de)	2004-07-15	Verfahren zur herstellung von 2-pyridylpiperidin-derivaten
DE59903764D1 (de)	2003-01-23	Verfahren zur herstellung von phytosqualan
DE50004440D1 (de)	2003-12-18	Verfahren zur herstellung von phosphonomethylglycin
DE60009060D1 (de)	2004-04-22	Verfahren zur herstellung von 2-pyridylpyridin-derivaten

Legal Events

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2005-06-15	UEP	Publication of translation of european patent specification	Ref document number: 1228056 Country of ref document: EP

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