ATE288761T1 - Verwendung von glykosaminoglykane zur behandlung seniler demenz - Google Patents
Verwendung von glykosaminoglykane zur behandlung seniler demenzInfo
- Publication number
- ATE288761T1 ATE288761T1 AT00925281T AT00925281T ATE288761T1 AT E288761 T1 ATE288761 T1 AT E288761T1 AT 00925281 T AT00925281 T AT 00925281T AT 00925281 T AT00925281 T AT 00925281T AT E288761 T1 ATE288761 T1 AT E288761T1
- Authority
- AT
- Austria
- Prior art keywords
- senile dementia
- glycosaminoglycans
- treat senile
- treatment
- alzheimer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7008—Compounds having an amino group directly attached to a carbon atom of the saccharide radical, e.g. D-galactosamine, ranimustine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
- C08B37/0078—Degradation products
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Neurosurgery (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Materials Engineering (AREA)
- Neurology (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Treatments Of Macromolecular Shaped Articles (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT1999MI001066A IT1312107B1 (it) | 1999-05-14 | 1999-05-14 | Glicosaminoglicani aventi peso molecolare medio di 2400 d atti altrattamento della demenza senile |
PCT/EP2000/004311 WO2000069444A1 (en) | 1999-05-14 | 2000-05-12 | Glycosaminoglycans having an average molecular weight equal to 2400 d suitable for the treatment of senile dementia |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE288761T1 true ATE288761T1 (de) | 2005-02-15 |
Family
ID=11382970
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00925281T ATE288761T1 (de) | 1999-05-14 | 2000-05-12 | Verwendung von glykosaminoglykane zur behandlung seniler demenz |
Country Status (22)
Country | Link |
---|---|
US (1) | US6979680B1 (de) |
EP (1) | EP1181024B1 (de) |
JP (1) | JP2002544233A (de) |
KR (1) | KR100711142B1 (de) |
CN (1) | CN1178667C (de) |
AT (1) | ATE288761T1 (de) |
AU (1) | AU764743C (de) |
CA (1) | CA2373975A1 (de) |
CZ (1) | CZ20014092A3 (de) |
DE (1) | DE60018061T2 (de) |
DK (1) | DK1181024T3 (de) |
ES (1) | ES2237425T3 (de) |
HK (1) | HK1039903B (de) |
HU (1) | HUP0201100A3 (de) |
IL (1) | IL146458A0 (de) |
IT (1) | IT1312107B1 (de) |
NO (1) | NO328902B1 (de) |
PL (1) | PL198016B1 (de) |
PT (1) | PT1181024E (de) |
RU (1) | RU2248800C2 (de) |
WO (1) | WO2000069444A1 (de) |
ZA (1) | ZA200109331B (de) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1344781A1 (de) | 2002-03-12 | 2003-09-17 | Laboratori Derivati Organici S.P.A. | Verfahren zur Depolymerisierung von Glykosaminoglykanen und so hergestellte Produkte |
ITMI20031023A1 (it) * | 2003-05-21 | 2004-11-22 | Umberto Cornelli | Glicosaminoglicani aventi peso molecolare medio 2400 d atti al trattamento delle disfunzioni emozionali. |
EP1524276A1 (de) * | 2003-10-16 | 2005-04-20 | Laboratori Derivati Organici S.P.A. | Mehrstufenverfahren für die physikalisische Depolymerisation von Heparin und die so erhaltenen Produkte |
US7939512B2 (en) | 2004-10-13 | 2011-05-10 | Laboratori Derivati Organici Spa | Multistep process for the physical depolymerization of heparin and products obtained therefrom |
CA2634871A1 (en) | 2005-12-22 | 2007-11-08 | Neurochem (International) Limited | Treatment of renal disorders, diabetic nephopathy and dyslipidemias |
WO2009007224A1 (en) * | 2007-07-10 | 2009-01-15 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Low molecular weight heparin derivatives having neuroprotective activity |
EP2283713B1 (de) | 2008-05-22 | 2018-03-28 | Vladimir Yegorovich Balakin | Vorrichtung zur krebstherapie mit geladenen teilchen mit mehreren achsen |
US8896239B2 (en) | 2008-05-22 | 2014-11-25 | Vladimir Yegorovich Balakin | Charged particle beam injection method and apparatus used in conjunction with a charged particle cancer therapy system |
CN102119586B (zh) | 2008-05-22 | 2015-09-02 | 弗拉迪米尔·叶戈罗维奇·巴拉金 | 多场带电粒子癌症治疗方法和装置 |
JP2011523169A (ja) | 2008-05-22 | 2011-08-04 | エゴロヴィチ バラキン、ウラジミール | 荷電粒子癌治療システムと併用する荷電粒子ビーム抽出方法及び装置 |
WO2009142547A2 (en) | 2008-05-22 | 2009-11-26 | Vladimir Yegorovich Balakin | Charged particle beam acceleration method and apparatus as part of a charged particle cancer therapy system |
JP2012519532A (ja) | 2009-03-04 | 2012-08-30 | ザクリトエ アクツィアニェールナエ オーブシチェストヴォ プロトム | 多方向荷電粒子線癌治療方法及び装置 |
US8609097B2 (en) * | 2009-06-10 | 2013-12-17 | Hoffmann-La Roche Inc. | Use of an anti-Tau pS422 antibody for the treatment of brain diseases |
EP2766495B1 (de) | 2011-10-14 | 2018-04-04 | Centre National De La Recherche Scientifique | Verfahren zur diagnose, prognose und behandlung von neurodegenerativen erkrankungen |
CN112426434A (zh) * | 2020-11-04 | 2021-03-02 | 山东大学 | 硫酸乙酰肝素在防治阿尔兹海默症中的应用 |
CN114478816A (zh) * | 2022-02-11 | 2022-05-13 | 上海兴糖生物技术有限公司 | 一种白玉蜗牛多糖及其制备方法和用途 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4351938A (en) * | 1980-05-19 | 1982-09-28 | Riker Laboratories, Inc. | Anticoagulant substance |
US4847338A (en) * | 1985-03-28 | 1989-07-11 | University Of Iowa Research Foundation | Low molecular weight heparin fragments as inhibitors of complement activation |
DE3789159T2 (de) * | 1986-05-01 | 1994-07-28 | Toppan Printing Co Ltd | Vorrichtung zur Simulation der Einstellung eines Abtasters. |
IT1213384B (it) * | 1986-11-24 | 1989-12-20 | Lab Derivati Organici Mediolan | Processo per la preparazione controllata di gilcosaminoglicani a basso peso molecolare. |
IT1205042B (it) * | 1987-05-28 | 1989-03-10 | Crinos Industria Farmaco | Composizione farmaceutica ad attivita' terapeutica per il trattamento della demenza senile di tipo alzheimer |
EP0337327A1 (de) * | 1988-04-09 | 1989-10-18 | Bioiberica, S.A. | Verfahren zur Herstellung von neuen Oligosaccharid-Fragmenten durch kontrollierte chemische Depolymerisation von Heparin |
IT1240615B (it) | 1990-04-03 | 1993-12-17 | Mediolanum Farmaceutici Spa | Impiego del dermatan solfato nella prevenzione e terapia dell'invecchiamento cerebrale e degli stati di deficit funzionale del sistema nervoso centrale |
-
1999
- 1999-05-14 IT IT1999MI001066A patent/IT1312107B1/it active
-
2000
- 2000-05-12 JP JP2000617903A patent/JP2002544233A/ja active Pending
- 2000-05-12 PT PT00925281T patent/PT1181024E/pt unknown
- 2000-05-12 CN CNB00807562XA patent/CN1178667C/zh not_active Expired - Fee Related
- 2000-05-12 WO PCT/EP2000/004311 patent/WO2000069444A1/en active IP Right Grant
- 2000-05-12 EP EP00925281A patent/EP1181024B1/de not_active Expired - Lifetime
- 2000-05-12 DE DE60018061T patent/DE60018061T2/de not_active Expired - Fee Related
- 2000-05-12 AT AT00925281T patent/ATE288761T1/de not_active IP Right Cessation
- 2000-05-12 CA CA002373975A patent/CA2373975A1/en not_active Abandoned
- 2000-05-12 DK DK00925281T patent/DK1181024T3/da active
- 2000-05-12 PL PL352070A patent/PL198016B1/pl not_active IP Right Cessation
- 2000-05-12 CZ CZ20014092A patent/CZ20014092A3/cs unknown
- 2000-05-12 US US10/048,542 patent/US6979680B1/en not_active Expired - Fee Related
- 2000-05-12 IL IL14645800A patent/IL146458A0/xx not_active IP Right Cessation
- 2000-05-12 HU HU0201100A patent/HUP0201100A3/hu unknown
- 2000-05-12 RU RU2001130882/14A patent/RU2248800C2/ru not_active IP Right Cessation
- 2000-05-12 AU AU44052/00A patent/AU764743C/en not_active Ceased
- 2000-05-12 KR KR1020017014505A patent/KR100711142B1/ko not_active IP Right Cessation
- 2000-05-12 ES ES00925281T patent/ES2237425T3/es not_active Expired - Lifetime
-
2001
- 2001-11-13 ZA ZA200109331A patent/ZA200109331B/xx unknown
- 2001-11-13 NO NO20015544A patent/NO328902B1/no not_active IP Right Cessation
-
2002
- 2002-02-28 HK HK02101550.8A patent/HK1039903B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
RU2248800C2 (ru) | 2005-03-27 |
AU764743C (en) | 2004-03-18 |
CA2373975A1 (en) | 2000-11-23 |
ZA200109331B (en) | 2002-08-28 |
IT1312107B1 (it) | 2002-04-04 |
PT1181024E (pt) | 2005-06-30 |
HUP0201100A2 (hu) | 2002-07-29 |
KR20020005033A (ko) | 2002-01-16 |
IL146458A0 (en) | 2002-07-25 |
CN1350459A (zh) | 2002-05-22 |
PL198016B1 (pl) | 2008-05-30 |
KR100711142B1 (ko) | 2007-04-24 |
NO328902B1 (no) | 2010-06-14 |
CZ20014092A3 (cs) | 2002-04-17 |
NO20015544D0 (no) | 2001-11-13 |
ES2237425T3 (es) | 2005-08-01 |
HK1039903A1 (en) | 2002-05-17 |
HUP0201100A3 (en) | 2003-03-28 |
CN1178667C (zh) | 2004-12-08 |
NO20015544L (no) | 2002-01-14 |
US6979680B1 (en) | 2005-12-27 |
AU764743B2 (en) | 2003-08-28 |
JP2002544233A (ja) | 2002-12-24 |
DK1181024T3 (da) | 2005-06-13 |
PL352070A1 (en) | 2003-07-28 |
HK1039903B (zh) | 2005-08-26 |
EP1181024B1 (de) | 2005-02-09 |
ITMI991066A1 (it) | 2000-11-14 |
DE60018061T2 (de) | 2006-04-13 |
EP1181024A1 (de) | 2002-02-27 |
DE60018061D1 (de) | 2005-03-17 |
AU4405200A (en) | 2000-12-05 |
WO2000069444A1 (en) | 2000-11-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1181024 Country of ref document: EP |
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REN | Ceased due to non-payment of the annual fee |