ZA200304809B - Process for the synthesis of a peptide having a tryptophan residue. - Google Patents

Process for the synthesis of a peptide having a tryptophan residue. Download PDF

Info

Publication number: ZA200304809B
Authority: ZA; South Africa
Prior art keywords: boc; trp; resin; peptide; pro
Prior art date: 2000-12-22

Application number

ZA200304809A

Other languages

English (en)

Inventor

Steven Allen Jackson

Original Assignee

Kinerton Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-22

Filing date

2003-06-20

Publication date

2004-04-20

2003-06-20 Application filed by Kinerton Ltd filed Critical Kinerton Ltd

2004-04-20 Publication of ZA200304809B publication Critical patent/ZA200304809B/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
- C07K1/061—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups
- C07K1/068—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using protecting groups for heterocyclic side chains
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Analytical Chemistry (AREA)
Endocrinology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA200304809A 2000-12-22 2003-06-20 Process for the synthesis of a peptide having a tryptophan residue. ZA200304809B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IE20001079		2000-12-22

Publications (1)

Publication Number	Publication Date
ZA200304809B true ZA200304809B (en)	2004-04-20

Family

ID=11042704

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200304809A ZA200304809B (en)	2000-12-22	2003-06-20	Process for the synthesis of a peptide having a tryptophan residue.

Country Status (25)

Country	Link
US (1)	US7122628B2 (ru)
EP (1)	EP1343808B1 (ru)
JP (1)	JP4064817B2 (ru)
KR (1)	KR100591832B1 (ru)
CN (2)	CN1481389A (ru)
AT (1)	ATE339442T1 (ru)
AU (1)	AU2002222439C1 (ru)
BR (1)	BR0116447B1 (ru)
CA (1)	CA2432708C (ru)
CZ (1)	CZ299141B6 (ru)
DE (1)	DE60123115T2 (ru)
DK (1)	DK1343808T3 (ru)
ES (1)	ES2266104T3 (ru)
HK (1)	HK1055749A1 (ru)
HU (2)	HU230601B1 (ru)
IE (1)	IES20011090A2 (ru)
IL (2)	IL156258A0 (ru)
MX (1)	MXPA03005678A (ru)
NO (1)	NO325038B1 (ru)
NZ (1)	NZ526990A (ru)
PL (1)	PL205949B1 (ru)
PT (1)	PT1343808E (ru)
RU (1)	RU2276156C2 (ru)
WO (1)	WO2002051861A2 (ru)
ZA (1)	ZA200304809B (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7091311B2 (en)	1996-06-07	2006-08-15	Smithkline Beecham Corporation	Peptides and compounds that bind to a receptor
EP1542714B1 (en)	2002-09-18	2014-04-02	Ortho-McNeil Pharmaceutical, Inc.	Methods of increasing platelet and hematopoietic stem cell production
US7576056B2 (en) *	2003-08-28	2009-08-18	Ortho-Mcneil Pharmaceutical, Inc.	Peptides and compounds that bind to a receptor
WO2007077112A1 (en) *	2005-12-30	2007-07-12	F. Hoffmann-La Roche Ag	Methods for the synthesis of arginine-containing peptides
CN103517915B (zh) *	2012-09-27	2015-11-25	深圳翰宇药业股份有限公司	一种制备布舍瑞林的方法
US10308677B2 (en)	2014-12-19	2019-06-04	Cem Corporation	Coupling method for peptide synthesis at elevated temperatures
US9969769B2 (en)	2014-12-19	2018-05-15	Cem Corporation	Coupling method for peptide synthesis at elevated temperatures

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4211693A (en) *	1977-09-20	1980-07-08	The Salk Institute For Biological Studies	Peptides with para-substituted phenylalanine
US4569927A (en) *	1984-02-23	1986-02-11	The Salk Institute For Biological Studies	GnRH Antagonists IV
IL74827A (en)	1984-05-21	1989-06-30	Salk Inst For Biological Studi	Peptides active as gnrh antagonists and pharmaceutical compositions containing them
IT1203600B (it) *	1985-12-06	1989-02-15	Phidea Srl	Metodo per preparare il (d-trp6)-lhrh
US5175254A (en) *	1988-09-24	1992-12-29	Societe D'expansion Scientifque Expansia	Solid phase peptide synthesis using a polyacrylic support in aqueous solution
GB8822502D0 (en) *	1988-09-24	1988-10-26	Expansia Sa	New peptide synthesis method
JPH05331188A (ja)	1992-05-28	1993-12-14	Nippon Chemiphar Co Ltd	トリペプチド、その製造方法及びエンドセリン拮抗剤

2001
- 2001-12-19 IL IL15625801A patent/IL156258A0/xx active IP Right Grant
- 2001-12-19 RU RU2003122779/04A patent/RU2276156C2/ru not_active IP Right Cessation
- 2001-12-19 DE DE60123115T patent/DE60123115T2/de not_active Expired - Lifetime
- 2001-12-19 US US10/451,486 patent/US7122628B2/en not_active Expired - Lifetime
- 2001-12-19 AU AU2002222439A patent/AU2002222439C1/en not_active Expired
- 2001-12-19 KR KR1020037008232A patent/KR100591832B1/ko not_active Expired - Lifetime
- 2001-12-19 AT AT01272223T patent/ATE339442T1/de active
- 2001-12-19 DK DK01272223T patent/DK1343808T3/da active
- 2001-12-19 CA CA2432708A patent/CA2432708C/en not_active Expired - Lifetime
- 2001-12-19 MX MXPA03005678A patent/MXPA03005678A/es active IP Right Grant
- 2001-12-19 CZ CZ20031634A patent/CZ299141B6/cs not_active IP Right Cessation
- 2001-12-19 CN CNA018210384A patent/CN1481389A/zh active Pending
- 2001-12-19 JP JP2002552954A patent/JP4064817B2/ja not_active Expired - Lifetime
- 2001-12-19 PL PL361993A patent/PL205949B1/pl unknown
- 2001-12-19 EP EP01272223A patent/EP1343808B1/en not_active Expired - Lifetime
- 2001-12-19 HU HU1400157A patent/HU230601B1/hu unknown
- 2001-12-19 NZ NZ526990A patent/NZ526990A/xx not_active IP Right Cessation
- 2001-12-19 CN CNA2007100047879A patent/CN101003563A/zh active Pending
- 2001-12-19 WO PCT/IE2001/000159 patent/WO2002051861A2/en active IP Right Grant
- 2001-12-19 HU HU0302633A patent/HU229701B1/hu unknown
- 2001-12-19 PT PT01272223T patent/PT1343808E/pt unknown
- 2001-12-19 BR BRPI0116447-3B1A patent/BR0116447B1/pt active IP Right Grant
- 2001-12-19 ES ES01272223T patent/ES2266104T3/es not_active Expired - Lifetime
- 2001-12-20 IE IE20011090A patent/IES20011090A2/en not_active IP Right Cessation
2003
- 2003-06-02 IL IL156258A patent/IL156258A/en unknown
- 2003-06-20 NO NO20032852A patent/NO325038B1/no not_active IP Right Cessation
- 2003-06-20 ZA ZA200304809A patent/ZA200304809B/en unknown
- 2003-11-04 HK HK03107934A patent/HK1055749A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
RU2003122779A (ru)	2005-02-20
IL156258A0 (en)	2004-01-04
NO325038B1 (no)	2008-01-21
IES20011090A2 (en)	2002-12-30
HU229701B1 (en)	2014-05-28
DK1343808T3 (da)	2006-12-11
DE60123115T2 (de)	2007-03-29
EP1343808A2 (en)	2003-09-17
CZ20031634A3 (cs)	2003-09-17
RU2276156C2 (ru)	2006-05-10
MXPA03005678A (es)	2003-10-06
AU2002222439B2 (en)	2005-04-07
JP2004516330A (ja)	2004-06-03
HUP0302633A2 (hu)	2003-12-29
BR0116447A (pt)	2003-10-07
CN1481389A (zh)	2004-03-10
CZ299141B6 (cs)	2008-04-30
WO2002051861A3 (en)	2002-10-10
HU230601B1 (hu)	2017-02-28
NO20032852D0 (no)	2003-06-20
US20040077827A1 (en)	2004-04-22
JP4064817B2 (ja)	2008-03-19
BR0116447B1 (pt)	2014-04-29
CN101003563A (zh)	2007-07-25
HUP0302633A3 (en)	2008-04-28
AU2002222439C1 (en)	2005-10-27
CA2432708A1 (en)	2002-07-04
CA2432708C (en)	2011-07-12
EP1343808B1 (en)	2006-09-13
KR100591832B1 (ko)	2006-06-20
NO20032852L (no)	2003-08-22
PL361993A1 (en)	2004-10-18
PT1343808E (pt)	2007-01-31
PL205949B1 (pl)	2010-06-30
WO2002051861A2 (en)	2002-07-04
HK1055749A1 (en)	2004-01-21
DE60123115D1 (de)	2006-10-26
KR20030081355A (ko)	2003-10-17
HUP1400157A2 (en)	2003-12-29
US7122628B2 (en)	2006-10-17
IL156258A (en)	2008-06-05
ATE339442T1 (de)	2006-10-15
NZ526990A (en)	2005-04-29
ES2266104T3 (es)	2007-03-01

Publication	Publication Date	Title
US7348404B2 (en)	2008-03-25	Solid-phase peptide synthesis and agent for use in such synthesis
CA1248700A (en)	1989-01-10	Gnrh agonists
FI91075B (fi)	1994-01-31	Menetelmä uusien terapeuttisesti käyttökelpoisten peptidien valmistamiseksi
Bajusz et al.	1989	Highly potent analogues of luteinizing hormone-releasing hormone containing D-phenylalanine nitrogen mustard in position 6.
ZA200107753B (en)	2002-05-13	Novel LHRH antagonists with improved solubility characteristics.
CA2432708C (en)	2011-07-12	Process for the synthesis of a peptide having a trp residue
AU2002222439A1 (en)	2003-01-23	Process for the synthesis of a peptide having a tryptophan residue
US5212288A (en)	1993-05-18	Temporary minimal protection synthesis of serine-containing polypeptides
Grandas et al.	1989	Convergent solid phase peptide synthesis. VII. Good yields in the coupling of protected segments on a solid support
US5432263A (en)	1995-07-11	Process for producing peptides with side chains containing imidazolinylamino, tetrahydropyrimidinylamino, or alkylguanidinyl groups
CA1335403C (en)	1995-04-25	Process and intermediates for lh-rh peptides
AU2005202990A1 (en)	2005-07-28	Process for the synthesis of a peptide having a tryptophan residue
FI102538B (fi)	1998-12-31	LH-RH-analogien synteesi väliaikaisella, pienimmällä mahdollisella suo jauksella
EP0056274A1 (en)	1982-07-21	Indole derivatives and a method for production of peptides
FI101884B (fi)	1998-09-15	Luteinisoivaa hormonia vapauttavan hormonin (LHRH) antagonistipeptidej ä
RU2043362C1 (ru)	1995-09-10	Способ твердофазного синтеза пептидов
Borin et al.	1973	Studies on cytochrome c. Part IV. Synthesis of the protected dodecapeptide (sequence 45–56) of Baker's yeast iso‐1‐cytochrome c
IL97216A (en)	1995-10-31	Temporary minimal protection in solid phase synthesis of LH HR analogues