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ZA200201085B - Benzofurane derivatives. - Google Patents

Benzofurane derivatives. Download PDF

Info

Publication number
ZA200201085B
ZA200201085B ZA200201085A ZA200201085A ZA200201085B ZA 200201085 B ZA200201085 B ZA 200201085B ZA 200201085 A ZA200201085 A ZA 200201085A ZA 200201085 A ZA200201085 A ZA 200201085A ZA 200201085 B ZA200201085 B ZA 200201085B
Authority
ZA
South Africa
Prior art keywords
formula
compound
ylcarbonyl
piperazinyl
protective group
Prior art date
Application number
ZA200201085A
Other languages
English (en)
Inventor
Andreas Bathe
Henning Boettcher
Bernd Helfert
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA200201085B publication Critical patent/ZA200201085B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Furan Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZA200201085A 1999-07-10 2002-02-07 Benzofurane derivatives. ZA200201085B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19932314A DE19932314A1 (de) 1999-07-10 1999-07-10 Benzofuranderivate

Publications (1)

Publication Number Publication Date
ZA200201085B true ZA200201085B (en) 2003-07-30

Family

ID=7914351

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200201085A ZA200201085B (en) 1999-07-10 2002-02-07 Benzofurane derivatives.

Country Status (29)

Country Link
US (1) US6531503B1 (uk)
EP (1) EP1194426B1 (uk)
JP (1) JP4908706B2 (uk)
KR (1) KR100709378B1 (uk)
CN (1) CN1178934C (uk)
AR (1) AR024671A1 (uk)
AT (1) ATE273973T1 (uk)
AU (1) AU767413B2 (uk)
BR (1) BRPI0012329B8 (uk)
CA (1) CA2378603C (uk)
CZ (1) CZ301441B6 (uk)
DE (2) DE19932314A1 (uk)
DK (1) DK1194426T3 (uk)
ES (1) ES2226884T3 (uk)
HK (1) HK1047275B (uk)
HU (1) HU229135B1 (uk)
IL (2) IL147494A0 (uk)
MX (1) MXPA02000316A (uk)
MY (1) MY122667A (uk)
NO (1) NO328209B1 (uk)
PL (1) PL196477B1 (uk)
PT (1) PT1194426E (uk)
RU (1) RU2278862C2 (uk)
SI (1) SI1194426T1 (uk)
SK (1) SK287360B6 (uk)
TR (1) TR200200017T2 (uk)
UA (1) UA73310C2 (uk)
WO (1) WO2001004112A2 (uk)
ZA (1) ZA200201085B (uk)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006060597A1 (de) 2006-12-21 2008-06-26 Merck Patent Gmbh Verfahren zur Herstellung von Benzofuran-2-carboxamiden
EP2110374A1 (en) * 2008-04-18 2009-10-21 Merck Sante Benzofurane, benzothiophene, benzothiazol derivatives as FXR modulators
AR076098A1 (es) * 2009-03-10 2011-05-18 Takeda Pharmaceutical Derivados de benzofurano
BR112012028445A2 (pt) 2010-05-06 2016-07-19 Bristol Myers Squibb Co compostos de heteroarila bicíclica como moduladores de gpr119
EP2566862B1 (en) 2010-05-06 2015-09-16 Bristol-Myers Squibb Company Benzofuranyl analogues as gpr119 modulators
CN102964323B (zh) * 2012-11-13 2015-03-25 苏州永健生物医药有限公司 一种5-（哌嗪-1-基）苯并呋喃-2-甲酰胺的合成方法
ES2661259T3 (es) * 2013-06-10 2018-03-28 Astellas Pharma Inc. Compuesto de amida heterocíclica aromática que contiene nitrógeno bicíclico

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2724915A (en) * 1955-11-29 Snow remover
DE2757532A1 (de) * 1977-12-23 1979-07-05 Hoechst Ag N,n'-disubstituiertes cyclisches diamin und verfahren zu dessen herstellung
BR9406823A (pt) * 1993-06-14 1996-03-26 Pfizer Aminas secundárias e agentes anti-diabéticos e antiobesidade
DE4333254A1 (de) * 1993-09-30 1995-04-06 Merck Patent Gmbh Piperidine und Piperazine
DE19514567A1 (de) * 1995-04-20 1996-10-24 Merck Patent Gmbh Benzofurane

Also Published As

Publication number Publication date
HK1047275A1 (en) 2003-02-14
IL147494A0 (en) 2002-08-14
MY122667A (en) 2006-04-29
HU229135B1 (en) 2013-08-28
SI1194426T1 (en) 2005-02-28
AU767413B2 (en) 2003-11-06
PL353157A1 (en) 2003-10-20
UA73310C2 (en) 2005-07-15
DE19932314A1 (de) 2001-01-11
AR024671A1 (es) 2002-10-23
HK1047275B (zh) 2005-09-02
NO328209B1 (no) 2010-01-11
MXPA02000316A (es) 2002-07-30
US6531503B1 (en) 2003-03-11
CN1356996A (zh) 2002-07-03
CA2378603C (en) 2010-05-11
BR0012329A (pt) 2002-03-19
CA2378603A1 (en) 2001-01-18
ATE273973T1 (de) 2004-09-15
BR0012329B1 (pt) 2013-03-19
JP2003504364A (ja) 2003-02-04
EP1194426B1 (de) 2004-08-18
SK62002A3 (en) 2002-05-09
EP1194426A2 (de) 2002-04-10
PL196477B1 (pl) 2008-01-31
CN1178934C (zh) 2004-12-08
NO20020095D0 (no) 2002-01-09
DK1194426T3 (da) 2004-12-20
SK287360B6 (sk) 2010-08-09
DE50007501D1 (de) 2004-09-23
HUP0201903A3 (en) 2005-02-28
AU6266500A (en) 2001-01-30
ES2226884T3 (es) 2005-04-01
WO2001004112A3 (de) 2001-08-02
RU2278862C2 (ru) 2006-06-27
KR100709378B1 (ko) 2007-04-20
JP4908706B2 (ja) 2012-04-04
KR20020016815A (ko) 2002-03-06
CZ301441B6 (cs) 2010-03-03
CZ200211A3 (cs) 2002-04-17
PT1194426E (pt) 2005-01-31
BRPI0012329B8 (pt) 2021-05-25
IL147494A (en) 2008-03-20
HUP0201903A2 (en) 2002-10-28
TR200200017T2 (tr) 2002-05-21
WO2001004112A2 (de) 2001-01-18
NO20020095L (no) 2002-01-09

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