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UY27436A1 - Compuestos químicos - Google Patents

Compuestos químicos

Info

Publication number
UY27436A1
UY27436A1 UY27436A UY27436A UY27436A1 UY 27436 A1 UY27436 A1 UY 27436A1 UY 27436 A UY27436 A UY 27436A UY 27436 A UY27436 A UY 27436A UY 27436 A1 UY27436 A1 UY 27436A1
Authority
UY
Uruguay
Prior art keywords
chemical compounds
solvates
salts
compounds
ibat
Prior art date
Application number
UY27436A
Other languages
English (en)
Inventor
Starke Ingemar
Dahlstrom Mikael
Blomberg David
Alenfalk Suzanne
Skjaret Tore
Lemurell Malin
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0121768A external-priority patent/GB0121768D0/en
Priority claimed from GB0209463A external-priority patent/GB0209463D0/en
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of UY27436A1 publication Critical patent/UY27436A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D285/00—Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/36—Seven-membered rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La presente invención se relaciona con compuestos de fórmula I en donde R son como se definen en la presente; sales, solvatos, solvatos de dichas sales y profármacos farmacéuticamente aceptables de los mismos y su uso como inhibidores del transporte de ácido biliar ileal(IBAT) para el tratamiento de hiperlipidemia. También se describen procesos para sus fabricación y composiciones farmacéuticas que los contienen.
UY27436A 2001-09-08 2002-09-06 Compuestos químicos UY27436A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0121768A GB0121768D0 (en) 2001-09-08 2001-09-08 Chemical compounds
GB0209463A GB0209463D0 (en) 2002-04-25 2002-04-25 Chemical compounds

Publications (1)

Publication Number Publication Date
UY27436A1 true UY27436A1 (es) 2003-04-30

Family

ID=26246524

Family Applications (1)

Application Number Title Priority Date Filing Date
UY27436A UY27436A1 (es) 2001-09-08 2002-09-06 Compuestos químicos

Country Status (29)

Country Link
US (1) US7132416B2 (es)
EP (1) EP1427423B9 (es)
JP (2) JP3616635B2 (es)
KR (1) KR100935623B1 (es)
CN (1) CN1582151A (es)
AR (1) AR037089A1 (es)
AT (1) ATE349214T1 (es)
AU (1) AU2002329387B2 (es)
BR (1) BRPI0212346B1 (es)
CA (1) CA2459449C (es)
CO (1) CO5570671A2 (es)
CY (1) CY1106348T1 (es)
DE (1) DE60217136T2 (es)
DK (1) DK1427423T5 (es)
ES (1) ES2278045T3 (es)
HK (1) HK1065258A1 (es)
HU (1) HU227623B1 (es)
IL (2) IL160691A0 (es)
IS (1) IS7170A (es)
MX (1) MXPA04002179A (es)
MY (1) MY131995A (es)
NO (1) NO327041B1 (es)
NZ (1) NZ531796A (es)
PL (1) PL216023B1 (es)
PT (1) PT1427423E (es)
RU (1) RU2305681C2 (es)
TW (1) TWI331143B (es)
UY (1) UY27436A1 (es)
WO (1) WO2003022286A1 (es)

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JP2004521961A (ja) 2004-07-22
MXPA04002179A (es) 2004-06-29
WO2003022286A1 (en) 2003-03-20
AU2002329387B2 (en) 2007-06-07
IL160691A0 (en) 2004-08-31
HUP0401196A2 (hu) 2004-10-28
PL369078A1 (en) 2005-04-18
CN1582151A (zh) 2005-02-16
ES2278045T3 (es) 2007-08-01
PT1427423E (pt) 2007-03-30
BRPI0212346B1 (pt) 2016-02-02
HK1065258A1 (en) 2005-02-18
IL160691A (en) 2011-11-30
EP1427423B9 (en) 2017-12-20
EP1427423A1 (en) 2004-06-16
AR037089A1 (es) 2004-10-20
ATE349214T1 (de) 2007-01-15
DE60217136T2 (de) 2007-09-27
CO5570671A2 (es) 2005-10-31
NZ531796A (en) 2005-10-28
EP1427423B1 (en) 2006-12-27
KR20040036935A (ko) 2004-05-03
JP2004210794A (ja) 2004-07-29
IS7170A (is) 2004-03-04
DK1427423T5 (da) 2018-04-09
HUP0401196A3 (en) 2008-01-28
NO20040948L (no) 2004-03-04
CA2459449A1 (en) 2003-03-20
US20050038009A1 (en) 2005-02-17
BR0212346A (pt) 2004-08-10
TWI331143B (en) 2010-10-01
HU227623B1 (en) 2011-09-28
RU2305681C2 (ru) 2007-09-10
KR100935623B1 (ko) 2010-01-07
JP3616635B2 (ja) 2005-02-02
NO327041B1 (no) 2009-04-06
US7132416B2 (en) 2006-11-07
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DE60217136D1 (de) 2007-02-08
CA2459449C (en) 2011-02-01
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PL216023B1 (pl) 2014-02-28

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