UA121852C2 - DERIVATIVES OF HETEROARYLPIPERIDINE AND -PIPERAZINE AS FUNGICIDES - Google Patents

Abstract

Compound formula.

Description

The invention relates to heteroarylpiperidine and -piperazine derivatives, their agrochemically active salts, their use, as well as methods and compositions for combating phytopathogenic harmful fungi in plants and/or on plants, or in seed material and/or on seed material of plants, methods of obtaining such compositions and processed seeds, and their use to combat phytopathogenic harmful fungi in agriculture, horticulture and forestry, veterinary medicine, in the field of material protection, as well as in the household and sanitation field. The presented invention also relates to a method of obtaining heteroarylpiperidine and -piperazine derivatives.

It is already known that some heterocyclic substituted thiazoles can be used as fungicidal compositions for crop protection (see documents MO 07/014290, UMO 08/013925,

MO 08/013622, MO 08/091594, MO 08/091580, MO 09/055514, MO 09/094407, MO 09/094445,

MO 09/132785, MO 10/037479, MO 10/065579, MO 11/076510, MO 11/018415, MO 11/018401,

MO 11/076699). However, the fungicidal effectiveness of these compounds, especially at relatively small rates of consumption, is not always satisfactory.

Since the environmental and economic requirements for modern compositions for crop protection are constantly increasing, for example, to the spectrum of their action, toxicity, selectivity, consumption amount, formation of harmful residues and ease of preparation, as well as in connection, for example, with the problem of the emergence of resistance to them , then there is a constant task of developing new plant protection agents, in particular, fungicides, which at least in some parameters have advantages compared to known agents.

Unexpectedly, it was found that the heteroarylpiperidine and -piperazine derivatives presented in this document provide solutions to at least part of the aspects of the above problems and in this connection are suitable for use as plant protection agents, especially as fungicides.

The invention relates to compounds of formula (I) 2

In THOSE vol

Uk x-a-0--v8

А-Й/ / («) p (I) in which each of the radicals is defined as indicated below:

A means phenyl, which may contain up to five substituents, where each substituent is independently selected from 277,

From or

A is an optionally benzofused, unsubstituted or substituted 5- or 6-membered heteroaryl which may contain up to four substituents, wherein each of the substituents on the carbon atom is independently selected from 2772 and each of the substituents on the nitrogen atom is independently selected from 73 , 2771 are the same or different and each independently means hydrogen, halogen, hydroxyl, thiol, nitro, cyano, -C(-O)H, -C(-O)OH, alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl , циклоалкіл, циклоалкеніл, галоциклоалкіл, галоциклоалкеніл, гідроксиалкіл, ціансалкіл, формілалкіл, алкоксиалкіл, галоалкоксиалкіл, циклоалкоксиалкіл, алкінілоксиалкіл, алкілтісалкіл, алкілсульфінілалкіл, алкіламіноалкіл, галоалкіламіноалкіл, циклоалкіламіноалкіл, діалкіламіноалкіл, алкілкарбонілалкіл, алкілсульфонілалкіл, алкілциклоалкіл, алкілциклоалкеніл, алкокси, алкілциклоалкілалкіл, галоциклоалкокси, алкілтіо , haloalkylthio, cycloalkylthio, alkynylthio, alkenyloxy, alkynyloxy, haloalkoxy, haloalkenyloxy, haloalkynyloxy, cycloalk кси, алкоксиалкокси, циклоалкілалкокси, алкілкарбонілокси, галоалкілкарбонілокси, циклоалкілкарбонілокси, циклоалкіламіно, алкілкарбоніламіно, циклоалкілкарбоніламіно, алкоксикарбоніламіно, алкілсульфоніламіно, галоалкілсульфоніламіно, фенілсульфоніламіно, циклоалкілалкіл, галоциклоалкілалкіл, циклоалкілциклоалкіл, алкоксиалкоксиалкіл, алкіламінокарбонілокси, алкілкарбонілалкокси, циклоалкіламінокарбоніл, циклоалкілалкоксикарбоніл, алкілсульфініл, галоалкілсульфініл, алкілсульфоніл, галоалкілсульфоніл, cycloalkylsulfonyl, alkylcarbonyl, haloalkylcarbonyl, cycloalkylcarbonyl, alkoxycarbonyl, cycloalkyloxycarbonyl, trialkylsilyl, -OE5, phenyl, -

S(-O)MAZVA" or -MAZV", 272 and VE! are the same or different and each independently means hydrogen, halogen, hydroxyl, thiol, nitro, cyano, -C(-O)H, -C(-OOH, alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl, cycloalkyl, halocycloalkyl , hydroxyalkyl, formylalkyl, alkoxyalkyl, alkylcarbonylalkyl, alkylcycloalkyl, alkoxy, alkylcycloalkylalkyl, alkylthio, haloalkylthio, alkynylthio, alkenyloxy,

алкінілокси, галоалкокси, алкоксиалкокси, алкілкарбонілокси, галоалкілкарбонілокси, циклоалкілкарбоніламіно, алкілсульфоніламіно, галоалкілсульфоніламіно, фенілсульфоніламіно, циклоалкілалкіл, галоциклоалкілалкіл, циклоалкілциклоалкіл, алкоксикарбонілокси, алкілкарбонілтіо, алкілсульфініл, галоалкілсульфініл, алкілсульфоніл, галоалкілсульфоніл, алкілкарбоніл, галоалкілкарбоніл, алкоксикарбоніл, алкіламінокарбонілокси, -С(-О) MAZA" or -MAZVU, 273, Ide2 and 72 are the same or different, and each independently means hydrogen, -С(-О)Н, -

C(-O)MAZA", alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl, cycloalkyl, halocycloalkyl, alkylcycloalkyl, cycloalkylalkyl, alkoxyalkyl, alkylsulfonyl, haloalkylsulfonyl, cycloalkylsulfonyl, phenylsulfonyl, alkylcarbonyl, haloalkylcarbonyl, alkoxyphenyl, haloalkoxycarbonyl, cycloalkyl, or benzyl,

BZ and CC" are the same or different and each independently represents hydrogen, alkyl, alkenyl, alkynyl, haloalkyl, cycloalkyl, benzyl or phenyl,

Y "means MV or C(BA 1)",

IN! is the same or different, and independently means hydrogen, halogen, hydroxyl, cyano, -C(-O)H, -C(-O)OH, alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl, alkoxyalkyl, alkylthioalkyl, alkylaminoalkyl, dialkylaminoalkyl, alkoxy, alkylthio, haloalkylthio, haloalkyloxy, alkylcarbonyloxy, alkylcarbonylamino, alkylcarbonylthio, alkylsulfonyl, haloalkylsulfonyl, alkylcarbonyl, haloalkylcarbonyl, alkoxycarbonyl, trialkylsilyloxy, -MAZA" or -C(-O)MAZV", or two BA" radicals, together with an atom carbon, to which they are attached, form a cyclopropyl ring, or two BA! radicals mean "СНг, -СОНВЗ, -МОВЗ or -СНМ(ВУ)",

Ve means hydrogen, -C(-O)H, alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl, cycloalkyl, halocycloalkyl, alkylcycloalkyl, cycloalkylalkyl, cycloalkylaminocarbonyl, haloalkylaminocarbonyl, alkylsulfonyl, haloalkylsulfonyl, cycloalkylsulfonyl, alkylcarbonyl, haloalkylcarbonyl, haloxycarbonyl, cycloalkoxycarbonyl, alkylaminocarbonyl, dialkylaminocarbonyl, phenyl or benzyl,

B" means alkyl, alkenyl, alkynyl, haloalkyl, cycloalkyl, benzyl or phenyl,

U means sulfur or oxygen,

Zo X means carbon or nitrogen,

IN? means hydrogen, alkyl, alkenyl, haloalkyl, alkoxy, halogen, cyano or hydroxyl,

R is oxo, alkyl, alkenyl, haloalkyl, alkoxy, halogen, cyano or hydroxyl, p is 0, 1 or 2, b is a 5-membered heteroaryl which is substituted by OO and may be unsubstituted or otherwise substituted, where each of the substituents on the carbon atom, independently selected from KU", and each of the substituents on the nitrogen atom, independently selected from Kg, o means a saturated or partially or fully unsaturated 5-membered heterocyclyl, which is substituted by 1 2-B'" , and may be unsubstituted or substituted in another way, where each of the substituents is independently selected from P",

B" is the same or different and independently means: attached to a carbon atom of a 5-membered heterocyclyl C): hydrogen, oxo, halogen, cyano, hydroxyl, nitro, -CHO, -С(-О0)OH, -С(-О )MN", -S(-O)MAZVU, -

МАЗВУ, алкіл, алкеніл, алкініл, галоалкіл, галоалкеніл, галоалкініл, циклоалкіл, галоциклоалкіл, алкілциклоалкіл, циклоалкілалкіл, циклоалкілциклоалкіл, галоциклоалкілалкіл, алкілциклоалкілалкіл, циклоалкеніл, галоциклоалкеніл, алкоксиалкіл, галоалкоксиалкіл, циклоалкоксиалкіл, алкоксиалкоксиалкіл, алкілтіоалкіл, формілалкіл, алкілкарбонілалкіл, алкілсульфінілалкіл, алкілсульфонілалкіл, алкіламіноалкіл, діалкіламіноалкіл, галоалкіламіноалкіл, циклоалкіламіноалкіл, алкілкарбоніл, галоалкілкарбоніл, циклоалкілкарбоніл, алкоксикарбоніл, циклоалкоксикарбоніл, циклоалкілалкоксикарбоніл, циклоалкіламінокарбоніл, гідроксиалкіл, алкокси, галоалкокси, циклоалкокси, галоциклоалкокси, циклоалкілалкокси, алкенілокси, галоалкенілокси, алкінілокси, галоалкінілокси, алкоксиалкокси, алкілкарбонілокси, галоалкілкарбонілокси, циклоалкілкарбонілокси, alkylcarbonylalkyloxy, alkylthio, haloalkylthio, cycloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, cycloalkylsulfonyl, trialkylsilyl, alkylsulfonylamino, haloalkylsulfonylamino, attached to the nitrogen atom of a 5-membered heterocyclyl C): hydrogen, alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl, cycloalkyl, halocycloalkyl, alkylcycloalkyl, cycloalkylalkyl, phenyl, benzyl, alkylsulfonyl, -C(-0О )H, alkoxycarbonyl or alkylcarbonyl, 60 2 means a simple bond, О, С(-О), 5(О)t, СНА2О or МВ2',

t is equal to 0, 1 or 2,

B2o means hydrogen, alkyl or haloalkyl,

B is hydrogen, alkyl, haloalkyl, cycloalkyl, alkylcarbonyl, haloalkylcarbonyl, alkoxycarbonyl or haloalkoxycarbonyl,

B is phenyl, benzyl, naphthalenyl, optionally benzofused, substituted 5- or b-membered heteroaryl, which is substituted at least once with a 7" substituent, and may be unsubstituted or otherwise substituted, wherein each substituent is independently selected from 77 and optional with 7, or

AB' means a 5- to 8-membered non-aromatic (saturated or partially saturated) carbocyclic ring, a 5-, 6- or 7-membered non-aromatic heterocyclic radical, or an 8- to 11-membered carbocyclic or heterocyclic bicyclic ring, each of which is substituted at least once by the substituent 727 and may be unsubstituted or otherwise substituted, wherein each substituent is independently selected from 27 and optionally from oxo, thio, or 7", 7 is hydrogen, halogen, hydroxyl, -HN, nitro, cyano , C(-O)H, alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl, cycloalkyl, cycloalkenyl, halocycloalkyl, halocycloalkenyl, hydroxyalkyl, alkyloxyalkyl, haloalkoxyalkyl, cycloalkoxyalkyl, alkylthialkyl, alkylsulfinylalkyl, alkylaminoalkyl, haloalkylaminoalkyl, cycloalkylsulfaminoalkyl, diallyl alkylcycloalkyl, alkoxy, alkylcycloalkylalkyl, halocycloalkyloxy, alkylthio, haloalkylthio, cycloalkylthio, alkenyloxy, alkynyloxy, haloalkyloxy, haloalkenyloxy, haloalkynyloxy, cycloalkyloxy, алкоксиалкокси, циклоалкілалкокси, алкілкарбонілокси, галоалкілкарбонілокси, циклоалкілкарбонілокси, циклоалкіламіно, алкілсульфоніламіно, галоалкілсульфоніламіно, циклоалкілалкіл, галоциклоалкілалкіл, циклоалкілциклоалкіл, алкоксиалкоксиалкіл, алкілкарбонілалкокси, циклоалкіламінокарбоніл, циклоалкілалкоксикарбоніл, алкілкарбонілтіо, алкілсульфініл, галоалкілсульфініл, алкілсульфоніл, галоалкілсульфоніл, циклоалкілсульфоніл, алкілкарбоніл, галоалкілкарбоніл, циклоалкілкарбоніл, алкоксикарбоніл, cycloalkoxycarbonyl, trialkylsilyl, -MAZV, -

C(-O) MAZV: or -I 523,

ИЗ means a simple bond, -СНе-, -С(-0)-, sulfur, oxygen, -С(-0)0-, -С(-О)МН-, -ООС(-0)- or -

Koo) MNO(-O)-, or

ИЗ means -MIN29-, -0(-5)-, -5(О)т-, -"СНА2О-, -"СНН-СНИАО-, -08Н02-С8Н2о-, -ОСНАгО-, -"СНИА?ОО- , 73 means a phenyl radical, a naphthalenyl radical, or a 5- or b-membered heteroaryl radical, each of which may contain 0, 1, 2, or 3 substituents, where each substituent is independently selected from the following list: substituents on the carbon atom: halogen, cyano . dialkylamino, alkylthio, haloalkylthio, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, trisilylalkyl or phenyl, substituents on the nitrogen atom: hydrogen, -C(-O)H, alkyl, alkenyl, alkynyl, haloalkyl, haloalkenyl, haloalkynyl, cycloalkyl, halocycloalkyl, alkylcycloalkyl , cycloalkylalkyl, alkoxyalkyl, alkylsulfonyl, haloalkylsulfonyl, cycloalkylsulfonyl, phenylsulfonyl, alkylcarbonyl, haloalkylcarbonyl, alkoxycarbonyl, haloalkoxycarbonyl, cycloalkoxycarbonyl, -C(-O)MAZAU, phenyl or benzyl, 2" means -MNOM, -502MNeM, -C(-O)OH, -C(-O)MH », -C(-5)MAZAU, -C(-O)MNOM, cyanoalkyl, alkenylcarbonyloxy, alkoxyalkylthio, haloalkenylcarbonyloxy, alkoxycarbonylalkyl, alkoxyalkynyl, alkynylthio, halocycloalkylcarbonyloxy, alkenylamino, alkynylamino, haloalkylamino, cycloalkylalkylamino, alkoxyamino, halocarbonylalkyloxyalamino, albonylamino Alkoxycarbonylamino, Alkylcarbonyl(alkyl)amino, Haloalkylcarbonyl(alkyl)amino, Alkoxycarbonyl(alkyl)amino, -MAZBO»23, Alkenylthio, Haloalkoxycarbonyl, Alkoxyalkylcarbonyl, -5E5, Haloalkoxycarbonylamino, -МНО(-О)Н, di(haloalkyl)aminealkyl, halocycloalkenyloxyalkyl, alkoxy(alkyl)aminocarbonyl, haloalkylsulfonylaminocarbonyl, alkoxycarbonylalkoxy, alkylaminothiocarbonylamino, cycloalkylalkylaminoalkyl, -С(-МОв НВ, alkylthiocarbonyl, cycloalkenyloxyalkyl, alko ксиалкоксикарбоніл, діалкіламінотіокарбоніламіно, алкілсульфоніламінокарбоніл, галоалкоксигалоалкокси, галоциклоалкоксиалкіл, -М-С(ВУ)», діалкіламінокарбоніламіно, алкоксиалкеніл, алкоксигалоалкокси, алкілтіокарбонілокси, галоалкоксиалкокси, -0502723, галоалкілсульфонілокси, алкілсульфонілокси, алкоксигалоалкіл, ди(галоалкіл)аміно, -502МАЗВУ, бо -О (0-5)MAZAYA, -0(0-5)58, di- alkoxyalkyl, alkylaminocarbonylamino, halo- oxyhaloalkyl,

alkylaminocarbonylalkylamino, trialylsilylalkynyloxy, trialylsilyloxy, trialylsilylalkynyl or --I 123, or 77 means cyano(alkyl)alkyl, dialkylthioalkyl, -O(C-O)H, -5СМ, alkoxysulfonyl, cycloalkylsulfinyl, -MA"B"2, -C( -O)MA" B", -BO»2MA "B: or 77 means alkyl, which can contain 1 or 2 substituents, where each of the substituents is independently selected from the following list: cyano, alkoxycarbonyl, -С(-М-ВУ) A8, -C(-M-MAZAUVV, alkylcarbonylamino,

haloalkylcarbonylamino, dialkylcarbonylamino, alkylcarbonyloxy, -C(-O)H, benzyloxy, benzoyloxy, -C(-O0)OH, alkenyloxy, alkynyloxy, haloalkenyloxy, haloalkynyloxy, halocycloalkyloxy, alkoxyamino, alkenylthio, alkynylthio, cycloalkylthio, haloalkyloxyamino, haloalkylthio, alkenylsulfinyl alkynylsulfinyl, cycloalkylsulfinyl, haloalkylsulfinyl, alkenylsulfonyl, alkynylsulfonyl, cycloalkylsulfonyl, haloalkylsulfonyl,

алкоксикарбонілокси, алкілкарбонілокси, циклоалкілкарбонілокси, галоалкілкарбонілокси, галоалкенілкарбонілокси, -5СМ, алкіламінокарбонілокси, алкілкарбоніл(алкіл)аміно, алкоксикарбоніл(алкіл)аміно, алкіламінокарбоніламіно, алкілсульфонілокси, галоалкоксикарбоніламіно, галоалкілкарбоніл(алкіл)аміно, галоалкілсульфонілокси, алкілсульфоніламіно, галоалкілсульфоніламіно, алкілтіокарбонілокси, ціаноалкокси,

циклоалкілалкокси, бензилоксиалкокси, алкоксигалоалкокси, алкоксиалкілтіо, алкоксиалкілсульфініл, алкоксиалкілсульфоніл, алкоксиалкілкарбонілокси, циклоалкоксиалкокси, галоалкоксиалкокси, галоалкоксигалоалкокси, алкоксикарбонілалкокси, алкілкарбонілалкокси, алкілтіоалкокси, діалкіламінокарбоніламіно, алкоксиалкоксиалкокси, триалкілсилілокси, триалкілсилілалкінілокси, алкінілциклоалкілокси, циклоалкілалкінілокси,

alkoxycarbonylalkynyloxy, arylalkynyloxy, alkylaminocarbonylalkynyloxy, dialkylaminocarbonylalkynyloxy, alkenylcarbonyloxy, alkynylcarbonyloxy, haloalkynylcarbonyloxy, cyanoalkylcarbonyloxy, cycloalkylsulfonyloxy, cycloalkylalkylsulfonyloxy, halocycloalkylsulfonyloxy, alkenylsulfonyloxy, alkynyloxysulfonyloxy, cyanoyl, alkylsulfonyl

haloalkynylsulfonyloxy, dialkylaminocarbonyloxy, haloalkylaminocarbonyloxy, M-alkyl-M- haloalkylaminocarbonyloxy, alkenyloxycarbonyl, alkynyloxycarbonyl, haloalkynyloxycarbonyl, cyanoalkyloxycarbonyl, alkenyloxysulfonyl, alkynyloxysulfonyl,

or 77 is alkenyl, which may contain 1 or 2 substituents, where each of the substituents is independently selected from the following list: trialkylsilyl, cycloalkyl, cyclopropylidenyl, alkoxy, trialkylsilyloxy, alkylcarbonyloxy, or 77 is alkynyl, which may contain 1 or 2 substituents, where each of substitutes independently selected from the following list:

cycloalkyl, cyclopropylidenyl,

or

77 means alkoxy, which may contain 1 or 2 substituents, where each of the substituents is independently selected from the following list:

Alkoxycarbonyl, cycloalkoxy, alkylcarbonyloxy, -O(C-O)H, alkylthio, hydroxyalkyl,

trialkylsilyl, cycloalkylsulfonyl, haloalkylsulfonyl, benzyloxy, alkyloxy,

alkylsulfonyl, cyano,

or

77 means alkenyloxy, which may contain 1 or 2 substituents, where each substituent is independently selected from the following list:

циклоалкіл, гідроксил, алкокси, алкенілокси, алкінілокси, галоалкокси, галоалкенілокси, галоалкінілокси, циклоалкокси, циклогалоалкокси, алкоксикарбоніл, галоалкоксикарбоніл, циклоалкоксикарбоніл, алкенілоксикарбоніл, галоалкенілоксикарбоніл, алкінілоксикарбоніл, галоалкінілоксикарбоніл, алкілкарбоніл, галоалкілкарбоніл, циклоалкілкарбоніл, циклогалоалкілкарбоніл, алкенілкарбоніл, галоалкенілкарбоніл, алкінілкарбоніл,

haloalkynylcarbonyl,

or 77 means alkynyloxy, which may contain 1 or 2 substituents, where each substituent is independently selected from the following list: cycloalkyl, alkoxycarbonyl, -23, alkylaminocarbonyl, dialkylaminocarbonyl or or

77 означає заміщений гідроксил, де замісник вибирають з наведеного нижче переліку: алкінілкарбоніл, галоалкінілкарбоніл, ціанокарбоніл, ціаноалкілкарбоніл, циклоалкілсульфоніл, циклоалкілалкілсульфоніл, галоциклоалкілсульфоніл, алкенілсульфоніл, алкінілсульфоніл, ціаноалкілсульфоніл, галоалкенілсульфоніл, галоалкінілсульфоніл, алкінілциклоалкіл, ціаноалкеніл, ціаноалкініл, алкоксикарбоніл, алкенілоксикарбоніл, алкінілоксикарбоніл, алкоксиалкілкарбоніл .

B" means hydrogen, alkyl, haloalkyl, benzyl or 273,

BZ means hydrogen, alkyl, haloalkyl, cycloalkylalkyl, cycloalkyl, alkylcycloalkyl, haloalkylcycloalkyl, alkoxyalkyl, haloalkyloxyalkyl, benzyl or phenyl,

B" means alkenyl, alkynyl, alkoxyalkyl, cyanoalkyl, formyl, haloalkyl, benzyl, phenyl, alkylcarbonyl, cycloalkyloxycarbonyl, alkoxycarbonyl, alkenyloxycarbonyl, alkynyloxycarbonyl, haloalkylcarbonyl, halocycloalkylcarbonyl, cycloalkylcarbonyl, cycloalkylcarbonyl, dialkylaminocarbonyl, dialkylaminothiocarbonyl,

B" means alkenyl, alkynyl, alkoxyalkyl, cyanoalkyl, formyl, hydrogen, haloalkyl, benzyl, phenyl, alkylcarbonyl, cycloalkyloxycarbonyl, alkoxycarbonyl, alkenyloxycarbonyl, alkynyloxycarbonyl, haloalkylcarbonyl, halocycloalkylcarbonyl, cycloalkylcarbonyl, cycloalkylcarbonyl, dialkylaminocarbonyl, dialkylaminothiocarbonyl, 7-C 0)0-, -С(-0)МАЗ-, -0О0(-0)-, -МАЗО(-О0)-, - ОСНСЕС- or -"ОСН.СН-СНЯ, and salts, complexes of metals and M- oxides of compounds of formula (I).

The invention also relates to the use of compounds of formula (I) as a fungicide.

Claimed heteroarylpiperidine and -piperazine derivatives of formula (I) and salts, metal complexes and their M-oxides are very suitable for combating phytopathogenic harmful fungi.

The above-mentioned compounds according to the invention show, in particular, high fungicidal activity and can be used for plant protection, in the household and in the field of sanitation, as well as in the field of material protection.

Compounds of formula (I) may be present either in pure form or as a mixture of various possible isomeric forms, especially stereoisomers such as E and 7, threo and erythro, as well as optical isomers such as K and 5 isomers or atropoisomers , and, if necessary, also tautomers. Both E and 7 isomers, and threo and erythro isomers, as well as optical isomers, any desired mixtures of these isomers, and possible tautomeric forms are claimed.

The values of the radicals of the compounds of formula (I) according to the invention have the following preferred, more preferred and most preferred definitions:

A means mainly phenyl, which can contain up to two substituents, where each of the substituents is independently selected from the following list: halogen, cyano, hydroxyl, -MAZA", -С(-0О)MAZA", nitro, C.i.C.sub.6-alkyl , C2-Cv-alkenyl,

C2-Cv-alkynyl, C3-Cv-cycloalkyl, C2-Cv-haloalkyl, C2-Cv-haloalkenyl, C2-Cv-haloalkynyl,

C3-C6-halocycloalkyl, C1-C4-alkoxy, C1-C4-alkynyloxy, C1-C4-alkynyloxy,

C-C4-alkylthio, C-C-alkylsulfonyl, C-C-haloalkylthio, C-C-haloalkylsulfonyl,

C-C4-Alkoxy-C1-Cv-alkyl, Hydroxy-Ci-Ca-alkyl, C1-Cv-Alkylcarbonyl, C1-Cv-Alkoxycarbonyl,

C-Cv-alkylcarbonyloxy or -C(-O)H, or,

A means a predominantly heteroaromatic radical selected from the following group: furan-g-yl, furan-z3-yl, thiophen-2-yl, thiophen-3-yl, isoxazol-3-yl, isoxazol-4-yl, isoxazol-b -yl, pyrrole-1-yl, pyrrole-2-yl, pyrrole-3-yl, oxazol-2-yl, oxazol-4-yl, oxazol-5-yl, thiazol-2-yl, thiazol-4-yl , thiazol-5-yl, isothiazol-3-yl, isothiazol-4-yl, isothiazol-5-yl, pyrazol-1-yl, pyrazol-3-yl, pyrazol-4-yl, imidazol-1-yl, imidazole -2-yl, imidazol-4-yl, 1,2,3-triazol-1-yl, 1,2,4-triazol-1-yl, pyridin-2-yl, pyridin-3-yl, pyridin-4 -yl, pyridazin-3-yl, pyridazin-4-yl, pyrazin-2-yl, pyrazin-3-yl, pyrimidin-2-yl, pyrimidin-4-yl or pyrimidin-5-yl, which may contain up to two substituents, where each of the substituents is independently selected from the following list: substituents on the carbon atom: halogen, cyano, hydroxyl, nitro, -MAZA", Ci-Cv-alkyl, C2-Cv-alkenyl, Cg2-Cv-alkynyl,

C3-Cv-cycloalkyl, C1-Cv-haloalkyl, Cg-Cv-haloalkenyl, C2-Cv-haloalkynyl, C3-Cv-halocycloalkyl,

C-C-Alkoxy, C-C-halo-Alkoxy, C-C-Alkylthio, C-C-Alkylsulfonyl, C-C4-haloalkylthio,

C1-C4-haloalkylsulfonyl, C1-C4-alkoxy-C1-C4-alkyl, hydroxy-C1-C4-alkyl, C1-C4-alkylcarbonyl,

C-Cv-Alkoxycarbonyl, C1-Cv-Alkylcarbonyloxy or phenyl, substituents on the nitrogen atom: 60 C:-Cv-alkyl, C2-Cv-alkenyl, C2-Cv-alkynyl, C:-Cv-haloalkyl, C2-Cv- haloalkenyl,

C2-Cv-haloalkynyl, C3-C0-cycloalkyl-Ci-Cv-alkyl, C-Cv-haloalkylcarbonyl, phenyl, benzyl,

C1-C4-alkylsulfonyl, C1-C4-haloalkylsulfonyl, phenylsulfonyl, -SKeEON or

C.-Ct-alkylcarbonyl,

A means more preferably phenyl, which may contain up to two substituents, where each substituent is independently selected from the following list: fluorine, bromine, iodine, chlorine, cyano, nitro, methyl, ethyl, n-propyl, 1-methylethyl, 1,1 -dimethylethyl, chlorofluoromethyl, dichloromethyl, dichlorofluoromethyl, difluoromethyl, trichloromethyl, trifluoromethyl, cyclopropyl, ethoxy, 1-methylethoxy, n-propoxy, methoxy, trifluoromethoxy, difluoromethoxy, 1-methylethylthio, methylthio, ethylthio, n-propylthio, difluoromethylthio or trifluoromethylthio, or

A means more preferably a heteroaromatic radical selected from the following group: furan-g-yl, furan-z-yl, thiophen-2-yl, thiophen-3-yl, isoxazol-3-yl, isoxazol-4-yl, isoxazol- 5-yl, pyrrole-1-yl, pyrrole-2-yl, pyrrole-Z-yl, oxazol-2-yl, oxazol-4-yl, oxazol-5-yl, thiazol-2-yl, thiazol-4- yl, thiazol-5-yl, isothiazol-3-yl, isothiazol-4-yl, isothiazol-5-yl, pyrazol-1-yl, pyrazol-3-yl, pyrazol-4-yl, imidazol-1-yl, imidazol-2-yl, imidazol-4-yl, 1,2,3-triazol-1-yl, 1,2,4-triazol-1-yl, pyridin-2-yl, pyridin-3-yl, pyridin- 4-yl, pyridazin-3-yl, pyridazin-4-yl, pyrimidin-2-yl, pyrimidin-4-yl, or pyrimidin-5-yl, which may contain up to two substituents, wherein the substituents are the same or different, and each independently selected from the following list: substituents on the carbon atom: fluorine, chlorine, bromine, iodine, cyano, nitro, methyl, ethyl, n-propyl, 1-methylethyl, 1,1-dimethylethyl, chlorofluoromethyl, dichloromethyl, dichlorofluoromethyl, difluoromethyl, trichloromethyl , trifluoromethyl, cyclopropyl, ethoxy, 1-methylethoxy, n-propoxy, methoxy, trifluoromethoxy, difluoromethoxy, 1-methylethylthio, methylthio, ethylthio, n-propylthio, difluoromethylthio, trifluoromethylthio or phenyl, substituents on the nitrogen atom: methyl, ethyl, n-propyl, 1-methylethyl, methylsulfonyl, trifluoromethylsulfonyl, methylcarbonyl, trifluoromethylcarbonyl, chloromethylcarbonyl, 2,2 -trifluoroethyl, 2,2-difluoroethyl, 2,2-dichloro-2-fluoroethyl, 2-chloro-2-difluoroethyl or 2-chloro-2-fluoroethyl.

A means most preferably pyrazol-1-yl, which may contain up to two substituents, where each substituent is independently selected from the following list: methyl, ethyl, chlorine, bromine, fluorine, difluoromethyl or trifluoromethyl, or

A means most preferably phenyl, which may contain up to two substituents, where each substituent is independently selected from the following list: methyl, ethyl, iodo, chlorine, bromine, fluorine, methoxy, ethoxy, difluoromethyl or trifluoromethyl.

WZ and KK" are preferably the same or different and each independently represents hydrogen,

Ci-Cv-alkyl, Co-Cv-alkenyl, Cg-Cv-alkynyl, Ci-Cv-haloalkyl, C3-Cv-cycloalkyl, benzyl or phenyl, and more preferably hydrogen, methyl, ethyl, n-propyl, 1-methylethyl , n-butyl or 1,1-dimethylethyl,

Y7 means preferably C(B")2 (more preferably START-") or MA, and most preferably

sleep

BA" means mainly hydrogen, methyl, ethyl or cyclopropyl, or two BA" radicals, together with the carbon atom to which they are attached, form a cyclopropyl ring, or two B-! radicals mean "SNM(RU)",

BA" means more preferably hydrogen or methyl,

BY2 means preferably hydrogen, C1-C6-alkyl, C1-C4-haloalkyl, C3-C6-cycloalkyl, C1-C4-alkylsulfonyl, C1-C4-aluoxycarbonyl and more preferably hydrogen or methyl, and most preferably hydrogen,

VU is preferably the same or different and independently means C:i-Cv-alkyl, Co-Cv-alkenyl, Co-

C 1 -alkynyl, C 1 -C 2 -haloalkyl, C 3 -C 6 -cycloalkyl, benzyl or phenyl, and preferably hydrogen, methyl, ethyl, n-propyl, 1-methylethyl, n-butyl or 1,1-dimethylethyl,

U means predominantly oxygen or sulphur, and more preferably oxygen,

X means a carbon or nitrogen atom, and preferably a carbon atom,

IN? means preferably hydrogen, C1-C6-alkyl, C1-C4-alkenyl, C1-C4-haloalkyl, C1-C4-alkoxy, halogen, cyano or hydroxyl, and more preferably hydrogen, fluorine, chlorine, bromine or hydroxyl, and most preferably hydrogen or fluorine,

IN? means preferably oxo, C1-C6-alkyl, C1-C4-alkenyl, C1-C4-haloalkyl, C1-C4-alkoxy, halogen, cyano or hydroxyl, and more preferably fluorine, chlorine, bromine or hydroxyl, and most preferably fluorine, p is preferably equal to 0 - 1 and more preferably 0, о means mainly b nm (v, - v sh v" -Yv KM x/ M / Sh M

М-Х М--Х m- щ m sy - , this - , s - ve - В ,; sa1

M M in

M d Mo m -x -d ih du - ) chi ich si M vi M M M M M s - В , с6 - в, с7-, с8-, F-

M o U on KE in хх / Тк / TO х- х-х M s , sio - a" - in , where the bond marked "m" is attached directly to X and, where the bond marked "m/ ", is attached directly to с, сб means more preferably с, (2 or С, and most preferably с,

VU means mostly hydrogen or halogen, and more preferably hydrogen, o means mostly in in B in? in? me too oyu" y shchu 5 EgZ o gg z Zp t -o -i- o- M o - M ,oz- M o -,o5-,o- prishe zll ly li zhi i sdi sdi spi o - , 08 - ,0 - , 09 - Op - woo woo woo woo woo, "chic; t, t, eh, o2- she: ,oz - She: och - vet, o5- no, 06 - in? in? in? shchi OH p-shchi no no ,0"7- , 08 - ,09 - ,О20 - To - v? d? v? d? v?

And let's go

M ,02 - , Oz - ,0m - , 025 - , 026 -

In B in A

Ше ,027 - Ше: , Ov - ше: ,029 - , 00 - , Oz - в в' в в в mm ох вх м ом и де Деу, де де , 82 - , Оз - , о - , 055 - , 056 - in vu vu vi vu en ud dk y , 03 - 57 , 038 - Z , 02 - y , to - o ,F- 5 5 (F) y (F) y 5 5 5 tya y

That's all

M O in M z M M M

WHERE Я, о , 02 - iv) , оз - M , с - 9) , 05 - 9) , (б в? она ю- о, where the bond marked """ joins directly to C or I , and where the bond labeled "Z" is attached directly to 17 or C, or where the bond labeled "" is attached directly to I and the bond labeled "Z" is also attached directly to a ,

O means mostly ву у « В ВХ У у

K - - (c) (c); (c) M x earth x zm x earth x o 0-1 - 0-2 - ,024-3 - 0214 - ;

In t o u (c) in red 0-1 - or 071-2-x; where the bond labeled "x" attaches directly to c, and where the bond labeled "y" attaches directly to 12,

B" is preferably the same or different, and independently means attached to a carbon atom of a 5-membered heterocyclyl C): hydrogen, cyano, -MAZAYA, Ci-Cv-alkyl, Co-Cv-alkenyl, Co-Cv-alkynyl, Ci-Cv -haloalkyl,

C2-Cv-haloalkenyl, C2-Cv-haloalkynyl, C3-Cv-cycloalkyl, C3-Cv-halocycloalkyl, C3-

C1-halocycloalkyl, C1-C6-alkyl-C3-C6-cycloalkyl, C3-C6-cycloalkyl-C1-C6-alkyl, C1-C4-alkyl

Ci-C4-alkyl, C3-Cv-cycloalkyl-C1-Ca-alkyl, Ci-C--Alkoxy-C1-C4-Alkoxy-C1-Ca-alkyl,

C-C1-alkylthio-Ci-C-alkyl, C:-Cv-alkyloxy, C.-Cv-haloalkyloxy, C3-Cv-cycloalkyloxy,

C3-Cv-halocycloalkyloxy, C3-Cv-cycloalkyl-Ci-C4-alkoxy, C2-Cv-alkenyloxy,

C2-Cv-haloalkenyloxy, C2-Cv-alkynyloxy, C2-Cv-haloalkynyloxy, C-i-Cv-alkoxy-C1-C--alkoxy,

C-Cv-alkylcarbonyloxy, C-Cv-haloalkylcarbonyloxy, C3-Cv-cycloalkylcarbonyloxy,

C-Cv-alkylcarbonyl-C1-Cv-alkoxy, C-Cv-alkylthio, C-Cv-haloalkylthio, C3-Cv-cycloalkylthio, attached to the nitrogen atom of a 5-membered heterocyclyl C): hydrogen, -С(-О)Н , C1-C3-alkyl, C1-C8-alkylcarbonyl, C1-C8-alkylcarbonyl or benzyl,

AV? means more preferably hydrogen, cyano, methyl, trifluoromethyl, difluoromethyl or methoxymethyl, or

B" means most preferably hydrogen, 2 means mostly a single bond, -O-, -C(-0)-, -5(O)t-, -SNIV2O- or -MA2-, and more preferably a single bond , -C(-0)-, - SNIV2O- or -MA2"-, and most preferably a simple bond, t is preferably equal to 0 or 2,

Vo means preferably hydrogen, C:1-C6-alkyl, C1-C4-haloalkyl, and more preferably hydrogen, methyl, ethyl, trifluoromethyl,

IN? means preferably hydrogen, C1-C8-alkyl, C1-C8-haloalkyl, C1-C8-alkylcarbonyl, C1-C8-haloalkylcarbonyl, C1-C8-haloalkylcarbonyl or C1-C8-haloalkylcarbonyl, and is preferably hydrogen or methyl,

A" means preferably C5-C6-cycloalkenyl or C3-C6-cycloalkyl, where C5-C6-cycloalkenyl or

C3-C6-cycloalkyl is in each case substituted at least once with substituent 727, and may

Zo be unsubstituted or otherwise substituted, wherein each of the substituents is independently selected from 277 and optionally from 7717, and is more preferably substituted with cyclopentenyl, cyclohexenyl, cyclopentyl, cyclohexyl, or cycloheptyl, each of which may contain 1 or 2 substituents, wherein the substituents are each independently selected at least once from 7" and optionally from the following list: methyl, ethyl, methoxy, ethoxy, trifluoromethoxy, ethynyl, 2-propenyloxy, 2-propynyloxy, methylcarbonyloxy, ethylcarbonyloxy, trifluorocarbonyloxy, methylthio, ethylthio or trifluoromethylthio, or

B' means preferably phenyl, which is substituted at least once by the substituent 27, and may be unsubstituted or substituted in another way, where each of the substituents is independently selected from 27 and optionally from 272, and more preferably phenyl, which may contain 1, 2 or C substituents, wherein the substituents are each independently selected at least once from 27, and optionally from the following list: fluorine, chlorine, bromine, iodine, cyano, nitro, hydroxyl, amino, -5H, -C(-O)H , methyl, ethyl, n-propyl, 1-methylethyl, n-butyl, 1,1-dimethylethyl, 1,2-dimethylethyl, ethenyl, ethynyl, trifluoromethyl, difluoromethyl, trichloromethyl, dichloromethyl, cyclopropyl, methoxy, ethoxy, n-propoxy . , chloromethylcarbonyloxy, methylthio, ethylthio, methylsulfonyl, methylsulfonylamino, trifluorometh ylsulfonylamino or -y1 383, and most preferably phenyl containing one substituent, wherein the substituent is selected from the following list:

M-methoxy-M-methylaminocarbonyl, -С(-МОН)Н, -С(-МОСН3)Н, -С(-МОСНеСН3)Н, (-(-

С(-МОСН(СН3)СН3)Н, -С(-МОН)СН», -С(-МОСН3)СнН3, -С(-МОСНоСН»3)СНаз, -

С(-МОСН(СН3)СН3)СнН3, dimethylaminosulfonyl, C(ЕОМН», ethylaminosulfonyl, trimethylsilylethynyl, diethylaminosulfonyl, methylaminosulfonyl, trimethylsilyloxy, trimethylsilylethynyloxy, trifluoromethylamino, dimethylaminocarbonylamino, С(:О)OH, 1,1-dimethylethylcarbonylamino, chloromethylcarbonylamino, triaminofluoromethylcarbonyl , - 1,1-dimethylethoxycarbonylamino, ethylcarbonylamino, 1-methylethoxycarbonylamino,

trifluoromethylcarbonylamino, methylcarbonylamino, 1-methylethylcarbonylamino, trifluoromethylsulfonyloxy, methylsulfonyloxy or phenylsulfonylamino,

AB" means mainly naphthalene-1-yl, naphthalene-2-yl, 1,2,3,4-tetrahydronaphthalene-1-yl, 1,2,3,4-tetrahydronaphthalene-2-yl, 5,6,7, 8-tetrahydronaphthalene-1-yl, 5,6,7,8-tetrahydronaphthalene-2-yl, decalin-1-yl, decalin-2-yl, 1H-inden-1-yl, 2,3-dihydro-1H- inden-1-yl, 1H-inden-2-yl, 1H-inden-3-yl, 1H-inden-4-yl, 1H-inden-5-yl, 1H-inden-b-yl, 1H-inden- 7-yl, indan-1-yl, indan-2-yl, indan-Z-yl, indan-4-yl or indan-5-yl, each of which is substituted at least once by substituent 77, and may be unsubstituted or otherwise substituted, wherein the substituents are each independently selected from 27, and optionally from 2"-

WITH,

B' means more preferably naphthalene-1-yl, naphthalene-2-yl, 1,2,3,4-tetrahydronaphthalene-1-yl, 1,2,3,4-tetrahydronaphthalene-2g-yl, 5,6,7 ,8-tetrahydronaphthalen-1-yl, 5,6,7,8-tetrahydronaphthalen-2-yl, decalin-1-yl, decalin-2-yl, 1H-inden-1-yl, 2,3-dihydro-1H -inden-1-yl, 1H-inden-2-yl, 1H-inden-3-yl, 1H-inden-4-yl, 1H-inden-5-yl, 1H-inden-b-yl, 1H-inden -7-yl, indan-1-yl, indan-2-yl, indan-Z-yl, indan-4-yl or indan-5-yl, each of which is substituted at least once by a 7" substituent and otherwise may additionally contain substituents, each independently selected from 7" and optionally a group including methyl, methoxy, cyano, fluoro, chlorine, bromine and iodine, where in a particularly preferred embodiment no more than three substituents are present in total,

A' means a preferably 5- or b-membered heteroaryl radical which is substituted at least once by the substituent 27", and may be unsubstituted or otherwise substituted, where the substituents on carbon are each independently selected from 27 and optionally from 27, and substituents on nitrogen, each independently selected from 22,

B' means more preferably furan-2-yl, furan-3-yl, thiophene-2-yl, thiophene-3-yl, isoxazol-3-yl, isoxazol-4-yl, isoxazol-b-yl, pyrrole-1 -yl, pyrrole-2-yl, pyrrole-3-yl, oxazol-2-yl, oxazol-4-yl, oxazol-b-yl, thiazol-2-yl, thiazol-4-yl, thiazol-5-yl , isothiazol-3-yl, isothiazol-4-yl, isothiazol-5-yl, pyrazol-1-yl, pyrazol-3-yl, pyrazol-4-yl, imidazol-y-yl, imidazol-2-yl, imidazole -4-yl, 1,2,4-oxadiazol-3-yl, 1,2,4-oxadiazol-5-yl, 1,3,4-oxadiazol-3-yl, 1,2,4-thiadiazole-3 -yl, 1,2,4-thiadiazol-5-yl, 1,3,4-thiadiazol-2-yl, 1,2,3-triazol-1-yl, 1,2,3-triazol-g-yl , 1,2,3-triazol-ad-yl, 1,2,4-triazol-1-yl, 1,2,4-triazol-3-yl, 1,2,4-triazol-4-yl, pyridine -2-yl, pyridin-3-yl, pyridin-4-yl, pyridazin-3-yl, pyridazin-4-yl, pyrimidine-2-yl, pyrimidine-4-yl, pyrimidine-5-yl or pyrazin-2 -yl, each of which may contain 1 or 2 substituents, where the substituents are each independently selected at least once from 7" and optionally from the following list: substituents on the carbon atom: fluorine, chlorine, bromine, iodine, cyano, nitro, hydroxyl, amino, -5H, -

С(5О)Н, methyl, ethyl, n-propyl, 1-methylethyl, n-butyl, 1,1-dimethylethyl, 1,2-dimethylethyl, ethenyl, ethynyl, trifluoromethyl, difluoromethyl, trichloromethyl, dichloromethyl, cyclopropyl, methoxy, ethoxy, n-propoxy, 1-methylethoxy, 1,1-dimethylethoxy, methylcarbonyl, ethylcarbonyl, trifluoromethylcarbonyl, methoxycarbonyl, ethoxycarbonyl, n-propoxycarbonyl, 1-methylethoxycarbonyl, 1,1-dimethylethoxycarbonyl, 1-ethenyloxy, 2-propenyloxy, 2- propynyloxy, methylcarbonyloxy, trifluoromethylcarbonyloxy, chloromethylcarbonyloxy, methylcarbonylamino, trifluoromethylcarbonylamino, chloromethylcarbonylamino, methylthio, ethylthio, methylsulfinyl, methylsulfonyl, methylsulfonyloxy, trifluoromethylsulfonyloxy, methylsulfonylamino or trifluoromethylsulfonylamino, substituents on the nitrogen atom: methyl, ethyl, -Н-propyl , methylcarbonyl, trifluoromethylcarbonyl, chloromethylcarbonyl, methylsulfonyl, trifluoromethylsulfonyl, phenylsulfonyl, phenyl or 2-propynyl, or

AB means a preferably benzofused substituted 5- or b-membered heteroaryl which is substituted with at least one substituent 77 and may be unsubstituted or otherwise substituted, wherein the carbon substituents are each independently selected from 715 and the nitrogen substituents are each independently selected from 72 , and more preferably indol-1-yl, indol-2-yl, indol-3-yl, indol-4-yl, indol-

BO B-yl, indol-b-yl, indol-7-yl, benzimidazol-1-yl, benzimidazol-2-yl, benzimidazol-4-yl, benzimidazol-

B-yl, indazol-1-yl, indazol-3-yl, indazol-4-yl, indazol-5-yl, indazol-b-yl, indazol-7-yl, indazol-2-yl, 1-benzofuran- 2-yl, 1-benzofuran-3-yl, 1-benzofuran-4-yl, 1-benzofuran-5-yl, 1-benzofuran-6-yl, 1-benzofuran-7-yl, 1-benzothiophen-2- yl, 1-benzothiophen-3-yl, 1-benzothiophen-4-yl, -1- benzothiophen-5-yl, 1-benzothiophen-b-yl, 1-benzothiophen-7-yl, 1,3-benzothiazol-g2 -yl, 1,3-benzothiazol-4-yl, 1,3-benzothiazol-b5-yl, 1,3-benzothiazol-b-yl, 1,3-benzothiazol-7-yl, 1,3-benzoxazol-g2 -yl, 1,3-benzoxazol-4-yl, 1,3-benzoxazol-5-yl, 1,3-benzoxazol-b-yl, 1,3-benzoxazol-7-yl, quinolin-2-yl, quinoline -Z-yl, quinoline-4-yl, quinoline-5-yl, quinoline-b-yl, quinoline-7-yl, quinoline-8-yl, isoquinolin-1-yl, isoquinoline-Z-yl, isoquinoline-4 -yl, isoquinolin-5-yl, isoquinolin-b-yl, isoquinolin-7-yl or isoquinolin-8-yl, each of which may contain up to two substituents, where each substituent is independently selected from the following list:

substituents on the carbon atom: fluorine, chlorine, bromine, iodine, methyl, methoxy, 2-propynyloxy, 2-propenyloxy, substituents on the nitrogen atom: methyl, ethyl, n-propyl, -С2(-0О)Н, methylcarbonyl, trifluoromethylcarbonyl, chloromethylcarbonyl, methylsulfonyl, trifluoromethylsulfonyl, phenylsulfonyl, phenyl or 2-propynyl, or

A" is preferably C5-C15-heterocyclyl which is substituted on carbon at least once by substituent 727 and may be unsubstituted or otherwise substituted, wherein the substituents, optionally on the carbon atom, are each independently selected from 775 and the substituents on nitrogen are each independently selected from 22,

B' means more preferably piperidin-1-yl, piperidin-2-yl, piperidin-3-yl, piperidin-4-yl, piperazin-1-yl, piperazin-2-yl, piperazin-3-yl, morpholin-1 -yl, morpholin-2-yl, morpholin-Z-yl, tetrahydropyran-2-yl, tetrahydropyran-Z-yl, tetrahydropyran-4-yl, 1,2,3,4-tetrahydroquinolin-1-yl, 1,2 ,3,4-tetrahydroisoquinolin-2-yl, 1,2,3,4-tetrahydroquinoxalin-1-yl, indolin-1-yl, isoindolin-2-yl, decahydroquinolin-1-yl or decahydroisoquinolin-2-yl, each of which may contain 1 or 2 substituents, wherein the substituents are each independently selected at least once from 77 and optionally from the following list: substituents on the carbon atom: fluoro, chloro, bromo, iodo, methyl, methoxy, 2-propynyloxy, 2 - propenyloxy, substituted on the nitrogen atom: methyl, ethyl, n-propyl, -C2(-0O)H, methylcarbonyl, trifluoromethylcarbonyl, chloromethylcarbonyl, methylsulfonyl, trifluoromethylsulfonyl, phenylsulfonyl, phenyl or 2-propynyl, 2171 are the same or different, and each independently means hydrogen, cyano, halogen, -С(-0О)Н,

C-Cv-alkyl, C-Cv-haloalkyl, C3-Cv-cycloalkyl, C2-Cv-alkenyl, C2-Cv-haloalkenyl, C2-Cv-alkynyl,

C2-Cv-haloalkynyl, hydroxyl, oxo, C-Cv-alkoxy, C:i-Cv-halo-alkoxy, C2-Cv-alkenyloxy,

C2-Cv-alkynyloxy, C:-Cv-alkylcarbonyloxy, Ci-Cv-haloalkylcarbonyloxy, Ci-Cv-alkylthio or

C-Cv-haloalkylthio, 7/2 means hydrogen, halogen, cyano, hydroxyl, -5H, nitro, -C(-O)H, -C(-0O)MAZAy, -MAZVU,

C:-Cv-alkyl, Co-Cv-alkenyl, C2-Cv-alkynyl, Ci-Cv-haloalkyl, Cg-Cv-haloalkenyl, C2-Cv-haloalkynyl,

C3-C8-cycloalkyl, C3-C8-halocycloalkyl, C3-C8-cycloalkenyl, C3-C8-halocycloalkenyl, / C1-C8-Alkoxy-C:i-C8-alkyl, C-C8-alkylcarbonyl, C-C8 -haloalkylcarbonyl,

C3-C8-cycloalkylcarbonyl, C3-C8-alkylcarbonyl, C3-C8-cycloalkylcarbonyl,

C3-C8-cycloalkylaminocarbonyl, C:-C8-alkoxy, C:-C8-haloalkyl, C3-C8-cycloalkyl,

C3-Cv-halocycloalkyloxy, C2-Cv-alkenyloxy, C2-Cv-haloalkenyloxy, C2-Cv-alkynyloxy,

C2-Cv-haloalkynyloxy, C1-C4-Alkoxy-Ci-C.-Alkoxy, C-Cv-Alkylcarbonyloxy,

C-Ce-hapoalkylcarbonyloxy, C3-Cv-cycloalkylcarbonyloxy, C1-Cv-alkylcarbonyl-C1-C-alkoxy,

C.-Cv-alkylthio, C.-Cv-haloalkylthio, C3-Cv-cycloalkylthio, C-Cv-alkylsulfonyl,

C-Cv-haloalkylsulfonyl, C3-Cv-cycloalkylsulfonyl, C-Cv-alkylsulfonylamino,

C-C6-haloalkylsulfonylamino, tri(C1-C4-alkyl)silyl or --I 373, iz and 775 are the same or different and each independently means hydrogen, halogen, cyano, nitro, -C(-O)H, - MAZAU, -C(-O)MAZAU, C1-Cv-alkyl, Cg-Cv-alkenyl, Cg-Cv-alkynyl, Ci-Cv-haloalkyl,

C2-Cv-haloalkenyl, C2-Cv-haloalkynyl, C1-C4-alkoxy-C1-Ca4-alkyl, C-Cv-alkylcarbonyl,

C-C-Alkoxycarbonyl, C-C-Alkoxy, C-C-Halo-Alkoxy, C-C-Alkylcarbonyloxy,

C1i-Cv-alkylcarbonylthio, C1-C4-alkylthio, C1-C4-haloalkylthio, C1-C4-alkylsulfonyl,

C1-C4-haloalkylsulfonyl or C1-Cv-haloalkylcarbonyloxy, 2717 means hydrogen, halogen, cyano, hydroxyl, -ZH, nitro, -C(-O)H, -C(-0O)MAZAy, -MAZVAU,

C:-Cv-alkyl, Co-Cv-alkenyl, C2-Cv-alkynyl, Ci-Cv-haloalkyl, Cg-Cv-haloalkenyl, C2-Cv-haloalkynyl,

C3-Cv-cycloalkyl, C3-Cv-halocycloalkyl, C3-Cv-cycloalkenyl, C3-Cv-halocycloalkenyl,

C-Cv-Alkoxy-C:-Cv-Alkyl, C.-Cv-Alkylcarbonyl, C.-Cv-haloalkylcarbonyl,

C3-C8-cycloalkylcarbonyl, C3-C8-alkylcarbonyl, C3-C8-cycloalkylcarbonyl, 5O C3-C8-cycloalkylaminocarbonyl, C:-C8-alkoxy, C:-C8-haloalkyl, C3-C8-cycloalkyl,

C3-Cv-halocycloalkyloxy, C2-Cv-alkenyloxy, C2-Cv-haloalkenyloxy, C2-Cv-alkynyloxy,

C2-Cv-haloalkynyloxy, C1-C4-Alkoxy-Ci-C.-Alkoxy, C-Cv-Alkylcarbonyloxy,

C-Cv-haloalkylcarbonyloxy, C3-Cv-cycloalkylcarbonyloxy, C-Cv-alkylcarbonyl-Ci1-C-alkoxy,

C-Ci-alkylthio, C-Ci-haloalkylthio, Ci-Ci-cycloalkylthio, Ci-Ci-alkylsulfonyl, Ci-Ci-haloalkylsulfonyl, Ci-Ci-cycloalkylsulfonyl, Ci-Ci-alkylsulfonylamino or

C-Cv-haloalkylsulfonylamino, 715 are the same or different, and each independently means hydrogen, cyano, halogen, -C(-0O)H, -

C(-O)MAZA", ofenyl, Ci-Cv-alkyl, Ci-Cv-haloalkyl, C3-Cv-cycloalkyl, Cg2-Cv-alkenyl,

C2-Cv-haloalkenyl, Co-Cv-alkynyl, C2-Cv-haloalkynyl, C-i-Cv-alkoxy, C-Cv-haloalkoxy, 60 C2-Cv-alkenyloxy, C2-Cv-alkynyloxy, C:-Cv- alkylthio, -MAZVU, Ci-Cv-alkylcarbonyl,

C1-C8-Alkoxycarbonyl, C1-C8-Alkylcarbonyloxy or C1-C8-Haloalkylthio, 22 is the same or different and independently means preferably hydrogen, C1-C8-alkyl,

C2-Cv-alkenyl, C2-Cv-alkynyl, C-Cv-haloalkyl, C2-Cv-haloalkenyl, C2-Cv-haloalkynyl, C1-Ca4- alkoxy-C1-Ca-alkyl, phenyl, benzyl, C1i-C4- -haloalkylsulfonyl, C1-C6-alkoxycarbonyl, C1-C6-haloalkoxycarbonyl, phenylsulfonyl, C1-C4-alkylsulfonyl, -C(-O)H, C1-C3-haloalkylcarbonyl or C1-C3-alkylcarbonyl,

B" means preferably hydrogen, C:1-Cv-alkyl, C1-Cv-haloalkyl, benzyl or 73, more preferably hydrogen, methyl, ethyl, n-propyl, 1-methylethyl, n-butyl, 1,1-dimethylethyl or 2-methylpropyl,

Ve means mainly hydrogen, C:i-Cv-alkyl, Ci-Cv-haloalkyl, C3-Cv-cycloalkyl-C1-C4-alkyl,

C3-Cv-cycloalkyl, C1-C4a-alkyl-C3-Cv-cycloalkyl, / C1-C«-haloalkyl-C3-Cv-cycloalkyl, /- C1-C4- alkoxy-C1-Ca-alkyl, C-C- -halo-C1-C-alkyl, benzyl or phenyl, more preferably hydrogen, methyl, ethyl, n-propyl, 1-methylethyl, n-butyl, 1,1-dimethylethyl or 2-methylpropyl,

ИZ means mainly a simple bond, -СНе-, sulfur, oxygen, -С(-0)0-, -Б(-О)МН-, -ОО0(-0)- or -МНО(-О)-, and more preferably a single bond, 73 is preferably a phenyl radical, naphthalenyl or a 5- or b-membered heteroaryl radical which may contain up to two substituents, where each substituent is independently selected from the following list: halogen, cyano, nitro, hydroxyl, amino, -5H, С1-Са-alkyl, Со-Са-alkenyl, Со-Са-alkynyl, С1-С4- haloalkyl, Со-С4-haloalkenyl, С2-С.-haloalkynyl, Со-С--alkoxyalkyl .

C2-C4-alkynyloxy, C1-C4-alkylthio, C1-C4-haloalkylthio, C1-C4-haloalkylsulfonyl, C1-C4-haloalkylsulfonyl or C1-C4-alkylamino, di(C1i-C--alkyl)amino, substituents on nitrogen atom: C-i-Cv-alkyl, C2-Cv-alkenyl, Cg2-Cv-alkynyl, C-Cv-haloalkyl,

C2-Cv-haloalkenyl, C2-Cv-haloalkynyl, C1-C4-alkoxy-Ci-C4-alkyl, phenyl, benzyl, C1-C4-haloalkylsulfonyl, C1-Cv-alkoxycarbonyl, C1-Cv-haloalkyl, phenylsulfonyl,

Ci-C-alkylsulfonyl, -C(2O)H, or Ci-C3-alkylcarbonyl, and 73 more preferably means a phenyl radical, which may contain up to two substituents, where each of the substituents is independently selected from the following list: chlorine, bromine, iodine , fluorine, cyano, nitro, hydroxyl, amino, -ZH, methyl, ethyl, n-propyl, 1-methylethyl, 1,1-dimethylethyl, ethenyl, propen-2-yl, ethynyl, propyn-2-yl, trifluoromethyl, difluoromethyl, methoxymethyl, methylcarbonyl, ethylcarbonyl, trifluoromethylcarbonyl, methoxycarbonyl, ethoxycarbonyl, n-propoxycarbonyl, 1-methylethoxycarbonyl, 1,1-dimethylethoxycarbonyl, methoxy, ethoxy, n-propoxy, 1-methylethoxy, 1,1-dimethylethoxy, trifluoromethoxy, ethenyloxy, or means more preferably naphthalenyl, 27" means mainly -С(-0)OH, -С(-0О)МН», -С(- 5) MAZV", cyano-Ci-Cv-alkyl, C2-Cv-alkenylcarbonyloxy, C2-Cv-alkynylthio, C3-Cv-halocycloalkylcarbonyloxy, C2-Cv-alkenylamino,

C2-Cv-alkynylamino, C.-Cv-haloalkylamino, C3-Cv-cycloalkyl-C1-Cv-alkylamino, C:-Cv- alkoxyamino, C-Cv-haloalkylamino, C-Cv-alkylcarbonylamino, C-Cv-haloalkylcarbonylamino,

C-Cv-Alkoxycarbonylamino, C1-Cv-alkylcarbonyl(C:1-Cv-alkyl)amino, C-Cv-haloalkylcarbonyl (Ci-

C1-C1-alkyl)damino, C1-C1-Alkoxycarbonyl(C:i-C1-Alkyl)amino, -MAZ50O273, C2-C1-Alkenylthio, C1-C1-halo-Alkoxycarbonyl, C1-C1-Alkoxy-C1-C4-Alkylcarbonyl . -М-С(ВУ)», di(Ci-Cv-alkyl)aminocarbonylamino, di(Ci-Cv-alkylaminosulfonyl, di(C:1-Cv-haloalkyl)amino, Ci-Cv-alkylaminosulfonyl, Ci-Cv-alkylaminocarbonylamino , tri(C1-Cα-alkyl)silyloxy, C-Cv-haloalkylsulfonyloxy, C-Cv-alkylsulfonyloxy, tri(C1-Cα-alkyl)silyl-C2-C4-alkynyloxy, tri(C1-Cα-alkyl)silyl-C2 -Са-alkynyl or --И 773, and more preferably - с(-ФОН, -С(-О)МН», -МНО(-О)Н, -С(-5)МAZВ», cyanomethyl, cyanoethyl, propenoyloxy , but-2-enoyloxy, propyn-2-ylthio, propen-2-ylamino, propyn-2-ylamino, trifluoromethylamino, difluoromethylamino, methoxyamino, ethoxyamino, propoxyamino, 1-methylethoxyamino, methoxycarbonylamino, ethoxycarbonylamino, 1-methylethoxycarbonylamino, 1,1 - dimethylethoxycarbonyl ino, trifluoromethylcarbonylamino, methylcarbonylamino, ethylcarbonylamino, 1-methylethylcarbonylamino, 1,1-dimethylethylcarbonylamino, phenylsulfonylamino, propen-g-ylthio, M-methoxy-M-methylaminocarbonyl, methoxycarbonylmethoxy, ethoxycarbonylmethoxy, propoxycarbonylmethoxy, 1-methylethoxycarbonylmethoxy, 1,1-methyldimethylcarbonylmethoxy -С(-МОов7г8, 60 dimethylaminocarbonylamino, diethylaminocarbonylamino, dimethylaminosulfonyl,

діетиламіносульфоніл, метиламіносульфоніл, етиламіносульфоніл, пропіламіносульфоніл, 1- метилетиламіносульфоніл, 1,1-диметилетиламіносульфоніл, метиламінокарбоніламіно, етиламінокарбоніламіно, пропіламінокарбоніламіно, 1-метилетиламінокарбоніламіно, 1,1- диметилетиламінокарбоніламіно, 2-метилпропіламінокарбоніламіно, 1- хлорциклопропілкарбонілокси, 1-фторциклопропілкарбонілокси, трифторметилсульфонілокси, триметилсилілокси, chloromethylcarbonylamino, trifluoromethylcarbonylamino, methylsulfonyloxy, ethylsulfonyloxy, trimethylsilylethynyloxy, trimethylsilylethynyl or -- 128, 27 means mainly -MA"B, -С(-0О)МА" Б, -502МА"Б2, -О(С-0О)Н, -50М . selected from the following list: cyano, -C(-O)H, C2-C4-alkenyloxy, Cg-C4-alkynyloxy, C2-C4-alkenylthio, Cg-C4-alkynylthio, C1-

C3-haloalkylthio, C2o-C4-alkenylsulfinyl, C2-C3-alkynylsulfinyl, C1-C3-haloalkylsulfinyl, C3-C3-alkenylsulfonyl, C2-C4-alkynylsulfonyl, C1-C3-haloalkylsulfonyl, C1-C3-alkylcarbonyloxy, C- C3-haloalkylcarbonyloxy, C1-C3-alkylaminocarbonyloxy, C1-C3-alkylcarbonylamino, C1-C3-alkylaminocarbonylamino, C1-C3-haloalkylcarbonylamino, C1-C3-alkylsulfonylamino, C1-C3-haloalkylsulfonylamino, C1-C3-alkylthiocarbonyloxy, cyano- C1-C3-Alkoxy, C3-C3-cycloalkyl-C1-C3-Alkoxy, C1-C3-Alkoxy-C1-C3-Alkylthio, C1-C3-Alkoxy-C1-C3-alkylsulfinyl, C1-C3-Alkoxy-C1- C3-alkylsulfonyl, C1-C3-haloalkyl-Ci-C3-alkoxy, C1-C3-alkylcarbonyl-Ci-C3-alkoxy, C2-C3-alkylthio-Ci--C3-alkoxy, di(C1i-C3-alkyl)aminocarbonylamino , tri(C1-C4-alkyl)silyloxy, or 27 means preferably C1-C3-alkoxy, which may contain 1 or 2 substituents, where each of the substituents is independently selected from the following list: cyano, C1-C3-alkylcarbonyloxy, C1-C3 -aluoxycarbonyl, C3-C3-cycloalkyloxy, /C1-C3- alkylcarbonyloxy, -FO(C-O )H, C1-C3-alkylthio, hydroxy-C1-C3-alkyl, C3-C6-cycloalkylsulfonyl,

C-C3-haloalkylsulfonyl, C1-C3-alkoxy-C1-C3-alkoxy, C1-C3-alkylsulfonyl, or 77 means preferably C2-C--alkenyloxy, which may contain 1 or 2 substituents, where each of

Among the substitutes independently selected from the following list:

C3-C6-cycloalkyl, hydroxyl, C1-C3-alkoxy, C1-C3-alkylcarbonyl, C1-C3-alkylcarbonyl, or 27 means preferably C2-C4-alkynyloxy, which may contain 1 or 2 substituents, where each substituent is independently selected from the following list:

C3-C8-cycloalkyl, -73, or 77 means preferably substituted hydroxyl, where the substituents are each selected from the following list:

С2-Са-alkynylcarbonyl, cyano-Сі-Сз-alkylcarbonyl, Сз-Св-cycloalkylsulfonyl, / Сз-Св- halocycloalkylsulfonyl, С2-С--alkenylsulfonyl, С:1-Сз-alkylaminocarbonyl, С2-С-alkynyl-Сз-

C-cycloalkyl, cyanocarbonyl, cyano-C2-C-alkenyl, -C(-O)MAZVU,

BA" means preferably C3-C-alkenyl, C3-C4-alkynyl, cyano-Ci-C3-alkyl, formyl, C:1-C3-haloalkyl, benzyl, phenyl, C3-C3-alkylcarbonyl, C3-C6-cycloalkylcarbonyl . C3-alkyl)aminocarbonyl,

B"2 means mainly hydrogen, C3-C4-alkenyl, C3-C4-alkynyl, cyano-C1-C3-alkyl, formyl, Ci-

C3-haloalkyl, benzyl, phenyl, C3-C3-alkylcarbonyl, C3-C3-cycloalkyloxycarbonyl, C3-C3-alkoxycarbonyl, C3-C3-alkenyloxycarbonyl, C3-C3-alkynyloxycarbonyl, C1-C3-haloalkylcarbonyl, C3-C3 -halocycloalkylcarbonyl, C3-C3-cycloalkylcarbonyl, C3-C3-cycloalkylcarbonyl, di(C1-C3-alkyl)aminocarbonyl,

And" means preferably -С(-0)0-, -С(-0)МН-, -00(-0)-, -МНО(-О)- or -ОСНоСЕС-, and more preferably -"ОСНоСЕС- or -С(-0)0-.

Suitable derivatives of heteroarylpiperidine and -piperazine according to the present invention are generally defined by formula (I). The values of the radicals above and of formula (I) below apply to the final products of formula (I) as well as to all intermediates (see also below under the heading "Explanation of Methods and Intermediates").

The radical definitions and explanations given above and below, in general or in order of preference, may be optionally combined with one another, ie, including combinations between in a particular order and in order of preference. They apply to both final products and, respectively, precursors and intermediate compounds. In addition, individual values may not be given.

Preference is given to those compounds of formula (I) in which all radicals have the above preferred values.

Particular preference is given to those compounds of formula (I) in which all radicals have the above-mentioned more preferred values.

The most particular preference is given to those compounds of formula (I) in which all radicals have the above-mentioned most preferred values.

In addition, preference is given to those compounds of formula (I) and agrochemically active salts, metal complexes and their M-oxides, in which:

A means 3,5-bisidifluoromethyl)-1H-pyrazol-1-yl or

A means 5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl, or

A means 5-chloro-2-methylphenyl, or

A means 3-(difluoromethyl)-5-methyl-1H-pyrazol-1-yl, or

A means 2,5-dimethylphenyl, or

A means 5-(difluoromethyl)-3-methyl-1H-pyrazol-1-yl, or

A means 2,5-bisidifluoromethyl)phenyl;

І means -СН»е- or І" means -МН-;

U means oxygen; c means C;

WOW! means hydrogen; o means 025-3 or 0) means 011-1;

B" means hydrogen or E:" means methyl; 2 means simple connection;

B means 2-13-(trimethylsilyl)prop-2-yn-1-yloxy)phenyl or

A" means 2-C1 E/2)-M-hydroxyethanemidoyl|phenyl or

A" means 3-(E/2)-Cpropan-2-yloxy)iminomethyluphenyl or

A" means 3-(E/7)-(ethoxyimino)methyl|phenyl or

A" means 3-C1E(2)-M-(propan-2-yloxy)ethanimidoyl|phenyl or

A" means 3-(E/7)-(methoxyimino)methyl|phenyl or

Zo A" means 3-(E/2)-(Hydroxyimino)methyl|Ifenyl or

A" means 2-(E/2)-Cpropan-2-yloxy)iminomethyluphenyl or

A" means 3-(1E/2)-M-hydroxyethanemidoyl|phenyl or

A" means 3-(1E/2)-N-methoxyethanemidoyl|phenyl or

B' means 4-(acetylamino)phenyl or

B" means 2-1 E/2)-M-(propan-2-yloxy)ethanimidoyl|phenyl or

B means 2-13-(naphthalen-1-yl)prop-2-yn-1-yl|hexyuphenyl or

B" means 2-(E/2)-(methoxyimino)umethyl|phenyl or

A" means 2-(E/2)-(ethoxyimino)methyl|phenyl or

B' means 2-C1E(7)-N-methoxyethanemidoyl|phenyl or

BA stands for 3-1 E/7)-M-ethoxyethanemidoylphenyl or

B means 4-C-tert-butoxycarbonyl)amino|phenyl or

A" means 2-(E/2)-(hydroxyimino)methyl|Ifenyl or

B' means 4,5-dimethyl-2-methylsulfonyl)oxy|phenyl or

B' means 2-carboxyphenyl or

B" means 2-Ketylsulfonyl)oxy|phenyl or

B' means 4-K(methylsulfonyl)oxy|phenyl or

B' means 2-formamidophenyl or

B' means 4-(2-methoxy-2-oxoethoxy)phenyl or

B means 2-Calyloxy)methylphenyl or

A" means 3-(cyanomethoxy)-2,6-difluorophenyl or

A" means 2-((2-methoxyethyl)sulfinyl|Imethyluphenyl or

A" means 2-(acetoxymethyl)-6-fluorophenyl or

A means 4-((cyclopropylsulfonyl)oxy|phenyl or

AB" means 3-chloro-2-(cyanomethoxy)phenyl or

B means 2-(4-fluorobenzoyl)oxy|phenyl or

B" means 3-fluoro-2-methylsulfonyl)oxy|phenyl or

B means 2,3-dimethoxy-6-Nmethylsulfonyl)oxy|phenyl or

B' means 2--Mtrifluoromethyl)sulfonyl|oxyphenyl or

B' means 2-(2E)-but-2-enoyloxy|phenyl or 60 B" means 2-fluoro-6-Cprop-2-yn-1-yloxy)methyl|phenyl or

B' means 2-Ketylcarbamoyl)oxy|phenyl or

B' means 5-chloro-2-((methylsulfonyl)oxy|phenyl or

A" means 2-(2-fluorobenzoyl)oxy|phenyl or

B means 2-N6formyl(prop-2-yn-1-ylaminophenyl or

A" means 2-((1-chlorocyclopropyl)carbonyl|oxyphenyl or

B" means 4-methyl-2-methylsulfonyl)oxy|phenyl or

B" means 4-chloro-2-methylsulfonyl)oxy|phenyl or

A means 2-((methylsulfonyl)oxy|phenyl or

AB" means 2-fluoro-6-KE/2)-(methoxyimino)methyl|phenyl or

B means 2-((cyclopropylsulfonyl)oxy|-3-fluorophenyl or

B' means 2-(cyanomethoxy)-4-methylphenyl or

B' means 2-Cprop-2-yn-1-yloxy)methylIfenyl or

B' means 2-(methylsulfanyl)methoxy|phenyl or

B means 2-(cyanomethoxy)-3-fluorophenyl or

A" means 2-methoxy-6-((methylsulfonyl)oxy|phenyl or

B' means 2-(acryloyloxy)phenyl or

B" means 3-chloro-2-methylsulfonyl)oxy|phenyl or

A means 2-Ctrimethylsilyl)ethynyl|phenyl or

A means 3-((cyclopropylsulfonyl)oxy|phenyl or

A" means 2-|(3-fluorobenzoyl)oxy|phenyl or

B means 2-((cyclopropylsulfonyl)oxy|-5-fluorophenyl or

B means 1-(2-cyanoethyl)-1H-pyrrol-2-yl or

B' means 2-(benzoyloxy)phenyl or

B' means 4-(cyanomethoxy)phenyl or

B' means 2-(dimethylcarbamothioylphenyl or

AB" means 5-chloro-2-(cyanomethoxy)phenyl or

A" means 2-(cyanomethoxy)-6-fluorophenyl or

A" means 2-((cyclopropylsulfonyl)oxy|phenyl or

A" means 2-((2-methoxyethyl)sulfonyl|methyl)phenyl or

Zo A" means 2-chloro-6-methylsulfonyl)oxy|phenyl or

B means 4-chloro-2-(cyanomethoxy)phenyl or

B means 3-11T3-(1-naphthyl)prop-2-yn-1-yl|oxy)phenyl or

B' means 4-Ketylsulfonyl)oxy|phenyl or

B' means 3-Ketylsulfonyl)oxy|phenyl or

AB" means 2-((2-methoxyethyl)sulfanyl|methyluphenyl or

B means 2,6-difluoro-3-Nmethylsulfonyl)oxy|phenyl or

B' means 5-methyl-2-methylsulfonyl)oxy|phenyl or

A" means 2-(cyanomethoxy)phenyl or

B" means 2-(cyanomethoxy)-5-methylphenyl or

A" means 2-((4-methylphenyl)sulfonyl|oxyphenyl or

B' means 2-(acetoxymethyl)phenyl or

B means 2-K(cyanomethyl)y(formyl)amino|phenyl or

B' means 3-(cyanomethoxy)phenyl or

B" means 2-chloro-6-(cyanomethoxy)phenyl.

The above radical values can be combined at will.

In addition, individual values may not be given.

According to the type of substituents defined above, the compounds of formula (I) have acidic or basic properties and can form salts, possibly also internal salts or adducts, with inorganic or organic acids, or with bases, or with metal ions. If the compounds of the formula (I) carry amino-, alkylamino- or other groups that induce basic properties, then these compounds can interact with acids to obtain salts, or they can be obtained directly as salts by synthesis. If the compounds of formula (I) carry hydroxyl, carboxyl or other groups that induce acidic properties, then these compounds can interact with bases, with the formation of salts. Acceptable bases are, for example, hydroxides, carbonates, bicarbonates of alkali and alkaline earth metals, especially sodium, potassium, magnesium and calcium, as well as ammonium, primary, secondary and tertiary amines having C.1-

C.4-alkyl groups, mono-, di- and trialkanolamines of C-C-alkanols, choline and chlorocholine.

Salts obtained in a similar way have fungicidal properties.

Examples of inorganic acids are hydrohalic acids such as hydrofluoric, 60 hydrogen chloride, hydrogen bromide and hydrogen iodide, sulfuric acid, phosphoric acid and nitric acid, and acid salts such as Manzo" and KNZO". Organic acids include, for example, formic acid, carbonic acid, and alkanoic acids such as acetic acid, trifluoroacetic acid, trichloroacetic acid, and propionic acid, as well as glycolic acid, thiocyanic acid, lactic acid, succinic acid, citric acid, benzoic acid, cinnamic acid acid, oxalic acid, saturated or mono- or di-unsaturated C-C0 fatty acids, alkylsulphuric monoesters, alkyleosulfonic acids (sulfonic acids having alkyl radicals with an unbranched or branched chain containing 1 to 20 carbon atoms), arylsulfonic acids or aryldisulfonic acids (aromatic radicals, such as phenyl and naphthyl bearing one or two sulfonic acid groups), alkylphosphonic acids (phosphonic acids having straight or branched chain alkyl radicals having 1 to 20 carbon atoms), arylphosphonic acids or aryldiphosphonic acids (aromatic radicals such as phenyl and naphthyl, which carry one or two phosphonic acid radicals), where the alc yl and aryl radicals can additionally carry substituents, for example, p-toluenesulfonic acids, salicylic acid, p-aminosalicylic acid, 2-phenoxybenzoic acid, 2-acetoxybenzoic acid, etc.

Useful metal ions are mainly those of the elements of the second main group, mainly calcium and magnesium, the third and fourth main groups, mainly aluminum, tin and lead, and also from the first to the eighth group of transition elements, mainly chromium, manganese, iron, cobalt, nickel, copper, zinc and others. Particular preference is given to metal ions of elements of the fourth period. Metals can be present in a variety of valences that they can assume.

Optionally substituted groups can be mono- or polysubstituted, where the substituents in the case of polysubstitutions can be the same or different.

In defining the symbols given in the formulas above, generally accepted terms were used, which are generally typical examples of such substitutes:

Halogen: fluorine, chlorine, bromine and iodine, and preferably fluorine, chlorine, bromine and more preferably fluorine, chlorine.

Alkyl: saturated, straight or branched hydrocarbyl radicals containing 1 to 8, preferably 1 to 6 and more preferably 1 to 3 carbon atoms, such as (but not limited to) C:-C 1 -alkyl such as methyl, ethyl, propyl, 1-methylethyl, butyl, 1-methylpropyl, 2-methylpropyl, 1,1-dimethylethyl, pentyl, 1-methylbutyl, 2-methylbutyl, 3-methylbutyl, 2,2-dimethylpropyl, 1-ethylpropyl, hexyl, 1,1-dimethylpropyl, 1,2-dimethylpropyl, 1-methylpentyl, 2-methylpentyl, 33-methylpentyl, 4-methylpentyl, 1,1-dimethylbutyl, 1,2-dimethylbutyl, 1,3-dimethylbutyl, 2, 2-dimethylbutyl, 2,3-dimethylbutyl, 3,3-dimethylbutyl, 1-ethylbutyl, 2-ethylbutyl, 1,1,2-trimethylpropyl, 1,2,2-trimethylpropyl, 1-ethyl-1-methylpropyl and 1- ethyl-2-methylpropyl. This definition also refers to alkyl as part of a compound substituent, for example, cycloalkylalkyl, hydroxyalkyl, etc., unless otherwise defined as, for example, alkylthio, alkylsulfinyl, alkylsulfonyl, haloalkyl, or haloalkylthio. If the alkyl is at the end of the compound substituent, as, for example, in alkylcycloalkyl, the portion of the compound substituent at the beginning, for example, cycloalkyl, may be mono- or polysubstituted, equally or differently, and independently by alkyl. The same also applies to component substituents in which other radicals, such as alkenyl, alkynyl, hydroxyl, halogen, formyl, etc., are at the end.

Alkenyl: unsaturated, straight or branched chain hydrocarbyl radicals containing 2 to 8, preferably 2 to 6 carbon atoms and one double bond at any position, such as (but not limited to) C2-C8-alkenyl, such as ethenyl, 1-propenyl, 2-propenyl, 1-methylethenyl, 1-butenyl, 2-butenyl, 3-butenyl, 1-methyl-1-propenyl, 2-methyl-1-propenyl, 1-methyl-2- propenyl, 2-methyl-2-propenyl, 1-pentenyl, 2-pentenyl, 3-pentenyl, 4-pentenyl, 1-methyl-1-butenyl, 2-methyl-1-butenyl, 3-methyl-1-butenyl, 1-methyl-2-butenyl, 2-methyl-2-butenyl, 3-methyl-2-butenyl, 1-methyl-3-butenyl, 2-methyl-3-butenyl, 3-methyl-3-butenyl, 1, 1-dimethyl-2-propenyl, 1,2-dimethyl-1-propenyl, 1,2-dimethyl-2-propenyl, 1-ethyl-1-propenyl, 1-ethyl-2-propenyl, 1-hexenyl, 2- hexenyl, 3-hexenyl, 4-hexenyl, 5-hexenyl, 1-methyl-1-pentenyl, 2-methyl-1-pentenyl, 3-methyl-1-pentenyl, 4-methyl-1-pentenyl, 1-methyl- 2-pentenyl, 2-methyl-2-pentenyl, 3-methyl-2-pentenyl, 4-methyl-2-pentenyl, 1-methyl-3-pentenyl, 2-methyl-3-pentene yl, 3-methyl-3-pentenyl, 4-methyl-3-pentenyl, 1-methyl-4-pentenyl, 2-methyl-4-pentenyl, 3-methyl-4-pentenyl, 4-methyl-4-pentenyl, 1,1-dimethyl-2-butenyl, 1,1,-dimethyl-3-butenyl, 1,2-dimethyl-1-butenyl, 1,2-dimethyl-2-butenyl, 1,2-dimethyl-3-butenyl , 1,3-dimethyl-1-butenyl, 1,3-dimethyl-2-butenyl, 1,3-dimethyl-3-butenyl, 2,2-dimethyl-3-butenyl, 2,3-dimethyl-1-butenyl , 2,3-dimethyl-2-butenyl, 2,3-dimethyl-3-butenyl, 3,3-dimethyl-1-butenyl, 3,3-dimethyl-2-butenyl, 1-ethyl-1-butenyl, 1 -ethyl-2-butenyl, 1-ethyl-3-butenyl, 2-ethyl-1-butenyl, 2-ethyl-2-butenyl, 2-ethyl-3-butenyl, 1,1,2-bo trimethyl-2- propenyl, 1-ethyl-1-methyl-2-propenyl, 1-ethyl-2-methyl-1-propenyl and 1-ethyl-2-methyl-

2-propenyl. This definition also applies to alkenyl as part of a complex substituent, eg, haloalkenyl, etc., unless otherwise specified.

Alkynyl: straight or branched chain hydrocarbyl groups containing 2 to 8, preferably 2 to 6 carbon atoms and one triple bond at any position, such as (but not limited to) C 2 -C 2 -alkynyl such as ethynyl, 1-propynyl, 2-propynyl, 1-butynyl, 2-butynyl, 3-butynyl, 1-methyl-2-propynyl, 1-pentynyl, 2-pentynyl, 3-pentynyl, 4-pentynyl, 1-methyl- 2-butynyl, 1-methyl-3-butynyl, 2-methyl-3-butynyl, 3-methyl-1-butynyl, 1,1-dimethyl-2-propynyl, 1-ethyl-2-propynyl, 1-hexynyl, 2-hexynyl, 3-hexynyl, 4-hexynyl, 5-hexynyl, 1-methyl-2-pentynyl, 1-methyl-3-pentynyl, 1-methyl-4-pentynyl, 2-methyl-3-pentynyl, 2- methyl-4-pentynyl, 3-methyl-1-pentynyl, 3-methyl-4-pentynyl, 4-methyl-1-pentynyl, 4-methyl-2-pentynyl, 1,1-dimethyl-2-butynyl, 1, 1-dimethyl-3-butynyl, 1,2-dimethyl-3-butynyl, 2,2-dimethyl-3-butynyl, 3,3-dimethyl-1-butynyl, 1-ethyl-2-butynyl, 1-ethyl- 3-butynyl, 2-ethyl-3-butynyl and 1-ethyl-1-methyl-2-propynyl. This definition also applies to alkynyl as part of a complex substituent, eg, haloalkynyl, etc., unless otherwise specified.

Alkoxy: Saturated, straight or branched chain alkoxy radicals containing 1 to 8, preferably 1 to 6 and more preferably 1 to 3 carbon atoms, such as (but not limited to) C1-C6-Alkoxy such as methoxy, ethoxy , propoxy, 1-methylethoxy, butoxy, 1-methylpropoxy, 2-methylpropoxy, 1,1-dimethylethoxy, pentoxy, 1-methylbutoxy, -2-methylbutoxy, 3-methylbutoxy, 2,2-dimethylpropoxy, 1-ethylpropoxy, hexoxy, /-1,1-dimethylpropoxy, 1,2-dimethylpropoxy, 1-methylpentoxy, 2-methylpentoxy, 3-methylpentoxy, 4-methylpentoxy, 1,1-dimethylbutoxy, 1,2-dimethylbutoxy, 1,3-dimethylbutoxy, /- (2,2-dimethylbutoxy, 2,3-dimethylbutoxy, 3,3-dimethylbutoxy, 1-ethylbutoxy, 2-ethylbutoxy, 1,1,2-trimethylpropoxy, 1,2,2-trimethylpropoxy, 1-ethyl-1-methylpropoxy and 1-ethyl-2-methylpropoxy.This definition also applies to alkoxy as part of a compound substituent, eg, haloalkyloxy, alkynylalkyloxy, etc., unless otherwise specified.

Alkylthio: Saturated straight or branched alkylthio radicals containing 1 to 8, preferably 1 to 6 and more preferably 1 to 3 carbon atoms, such as (but not limited to) Ci-Cv-alkylthio, such as methylthio, ethylthio , propylthio, 1-methylethylthio, butylthio, 1-methylpropylthio, 2-methylpropylthio, 1,1-dimethylethylthio, pentylthio, 1-methylbutylthio, 2-methylbutylthio, 3-methylbutylthio, 2,2-dimethylpropylthio, 1-ethylpropylthio, hexylthio, 1 ,1-dimethylpropylthio, 1,2-dimethylpropylthio, 1-methylpentylthio, 2-methylpentylthio, 3-methylpentylthio, 4-methylpentylthio, 1,1-dimethylbutylthio, 1,2-dimethylbutylthio, 1,3-dimethylbutylthio, 2,2-dimethylbutylthio0 , 2,3-dimethylbutylthio, 3,3-dimethylbutylthio, 1-ethylbutylthio, 2-ethylbutylthio, 1,1,2-trimethylpropylthio, 1,2,2-trimethylpropylthio, 1-ethyl-1-methylpropylthio and 1-ethyl-2 -methylpropylthio. This definition also applies to alkylthio as part of a complex substituent, eg, haloalkylthio, etc., unless otherwise specified.

Alkoxycarbonyl: An alkoxy group containing 1 - b, preferably 1 - C carbon atoms (as above) and is attached to the skeleton through a carbonyl group (-CO-). This definition also applies to alkoxycarbonyl as part of a complex substituent, for example, cycloalkylalkyloxycarbonyl, etc., unless otherwise specified.

Alkylsulfinyl: Saturated, straight or branched chain alkylsulfinyl radicals containing 1 to 8, preferably 1 to 6 and more preferably 1 to 3 carbon atoms, such as (but not limited to) Ci-Cv alkylsulfinyl such as methylsulfinyl, ethylsulfinyl , propylsulfinyl, 1-methylethylsulfinyl, butylsulfinyl, 1-methylpropylsulfinyl, -(:2-methylpropylsulfinyl, 1,1-dimethylethylsulfinyl, pentylsulfinyl, 1-methylbutylsulfinyl, 2-methylbutylsulfinyl, 3-methylbutylsulfinyl, 2,2-dimethylpropylsulfinyl, 1-ethylpropylsulfinyl, hexylsulfinyl, 1,1-dimethylpropylsulfinyl, 1,2-dimethylpropylsulfinyl, 1-methylpentylsulfinyl, 2-methylpentylsulfinyl, 3-methylpentylsulfinyl, 4-methylpentylsulfinyl, 11-dimethylbutylsulfinyl, 1,2- dimethylbutylsulfinyl, 1,3-dimethylbutylsulfinyl, 2,2- dimethylbutylsulfinyl, 2,3-dimethylbutylsulfinyl, 3,3-dimethylbutylsulfinyl, 1-ethylbutylsulfinyl, 2-ethylbutylsulfinyl, 1,1,2-trimethylpropylsulfinyl, 1,2,2-trimethylpropylsulfinyl, 1-ethyl-1-methylpropyl pilsulfinyl and 1-ethyl-2-methylpropylsulfinyl. This definition also applies to alkylsulfinyl as part of a complex substituent, for example, haloalkylsulfinyl, etc., unless otherwise specified.

Alkylsulfonyl: Saturated, straight or branched alkylsulfonyl radicals containing 1 to 8, preferably 1 to 6 and more preferably 1 to 3 carbon atoms, such as (but not limited to) Ci-Cv alkylsulfonyl such as methylsulfonyl, ethylsulfonyl , propylsulfonyl, 1-methylethylsulfonyl, butylsulfonyl, 1-methylpropylsulfonyl, 2-methylpropylsulfonyl, 1,1-dimethylethylsulfonyl, pentylsulfonyl, 1-methylbutylsulfonyl,

2-methylbutylsulfonyl, 3-methylbutylsulfonyl, 2,2-dimethylpropylsulfonyl, 1-ethylpropylsulfonyl, hexylsulfonyl, 1,1-dimethylpropylsulfonyl, 1,2-dimethylpropylsulfonyl, 1-methylpentylsulfonyl, 2-methylpentylsulfonyl, 3-methylpentylsulfonyl, 4-methylpentylsulfonyl, 1, 1-Dimethylbutylsulfonyl, 1,2-Dimethylbutylsulfonyl, 1,3-Dimethylbutylsulfonyl, 2,2-Dimethylbutylsulfonyl, 2,3-Dimethylbutylsulfonyl, 3,3-Dimethylbutylsulfonyl, 1-Ethylbutylsulfonyl, 2-Ethylbutylsulfonyl, 1,1,2-Trimethylpropylsulfonyl, 1,2,2-trimethylpropylsulfonyl, 1-ethyl-1-methylpropylsulfonyl and 1-ethyl-2-methylpropylsulfonyl. This definition also applies to alkylsulfonyl as part of a compound substituent, eg, alkylsulfonylalkyl, etc., unless otherwise specified.

Cycloalkyl: monocyclic, saturated hydrocarbyl groups containing C - 10, preferably 3 - 8 and more preferably 3 - 6 carbon ring members, such as (but not limited to) cyclopropyl, cyclopentyl and cyclohexyl. This definition also applies to cycloalkyl as part of a compound substituent, eg, cycloalkylalkyl, etc., unless otherwise specified.

Cycloalkenyl: monocyclic, partially unsaturated hydrocarbyl groups containing C - 10, preferably 3 - 8 and more preferably 3 - carbon ring members, such as (but not limited to) cyclopropenyl, cyclopentenyl and cyclohexenyl. This definition also applies to cycloalkenyl as part of a compound substituent, eg, cycloalkenylalkyl, etc., unless otherwise specified.

Cycloalkyloxy: monocyclic, saturated cycloalkyloxy groups containing C - 10, preferably 3 - 8 and more preferably 3 - 6 carbon ring members, such as (but not limited to) cyclopropyloxy, cyclopentyloxy and cyclohexyloxy. This definition also applies to cycloalkyl as part of a complex substituent, for example, cycloalkylalkyl, etc., unless otherwise specified.

Haloalkyl: straight or branched chain alkyl groups containing 1 to 8, preferably 1 to 6 and more preferably 1 to 3 carbon atoms (as above), where some or all of the hydrogen atoms in these groups may be replaced by halogen atoms, as listed above, for example (but not limited to) C1-C3-haloalkyl such as chloromethyl, bromomethyl, dichloromethyl, trichloromethyl, fluoromethyl, difluoromethyl, trifluoromethyl, chlorofluoromethyl,

Zo dichlorofluoromethyl, chlorodifluoromethyl, 1-chloroethyl, 1-bromomethyl, 1-fluoroethyl, 2-fluoroethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl, 2-chloro-2-fluoroethyl, 2-chloro-2,2 -difluoroethyl, 2,2-dichloro-2-fluoroethyl, 2,2,2-trichloroethyl, pentafluoroethyl and 1,1,1-trifluoroprop-2-yl. This definition also applies to haloalkyl as part of a complex substituent, eg, haloalkylaminoalkyl, etc., unless otherwise specified.

Haloalkenyl and haloalkynyl are defined similarly to haloalkyl, except that instead of alkyl groups, alkenyl and alkynyl groups are present as part of the substituent.

HaloAlkoxy: straight or branched chain alkoxy groups containing 1 to 8, preferably 1 to 6 and more preferably 1 to 6 carbon atoms (as above) where some or all of the hydrogen atoms in these groups may be replaced by halogen atoms as indicated above, for example (but not limited to) C 1 -C 3 -halomethoxy, such as chloromethoxy, bromomethoxy, dichloromethoxy, trichloromethoxy, fluoromethoxy, difluoromethoxy, trifluoromethoxy, chlorofluoromethoxy, dichlorofluoromethoxy, chlorodifluoromethoxy, 1-chloroethoxy, 1-bromomethoxy, 1-fluoroethoxy, 2-fluoroethoxy, 2,2-difluoroethoxy, 2,2,2-trifluoroethoxy, 2-chloro-2-fluoroethoxy, 2-chloro-2,2-difluoroethoxy, 2,2-dichloro-2-fluoroethoxy, 2,2, 2-trichloroethoxy, pentafluoroethoxy and 1,1,1-trifluoroprop-2-oxy. This definition also applies to haloalkoxy as part of a compound substituent, for example, haloalkoxyalkyl, etc., unless otherwise defined.

Haloalkylthio: straight or branched chain alkylthio groups containing 1 - 8, preferably 1 - 6 and more preferably 1 - C carbon atoms (as above) where some or all of the hydrogen atoms in these groups may be replaced by halogen atoms as above, for example (but not limited to) C1-C3-haloalkylthio, such as chloromethylthio, bromomethylthio, dichloromethylthio, trichloromethylthio, fluoromethylthio, difluoromethylthio, trifluoromethylthio, chlorofluoromethylthio, dichlorofluoromethylthio, chlorodifluoromethylthio, 1-chloroethylthio, 1-bromomethylthio, 1-fluoroethylthio, 2-fluoroethylthio, 2,2-difluoroethylthio, 2,2,2-trifluoroethylthio, 2-chloro-2-fluoroethylthio, 2-chloro-2,2-difluoroethylthio, 2,2-dichloro-2-fluoroethylthio, 2,2, 2-trichloroethylthio, pentafluoroethylthio and 1,1,1-trifluoroprop-2-ylthio. This definition also applies to haloalkylthio as part of a complex substituent, eg, haloalkyltisalkyl, etc., unless otherwise specified.

Heteroaryl: A 5- or b-h-ened, fully unfused monocyclic ring system containing one to four heteroatoms selected from the group consisting of oxygen, nitrogen, and sulfur; for in the case when the ring contains more than one oxygen atom, they cannot be directly adjacent;

B-membered heteroaryl containing one to four nitrogen atoms or one to three nitrogen atoms and one sulfur or oxygen atom: 5-membered heteroaryl groups which, in addition to carbon atoms, may contain one to four nitrogen atoms , or one to three nitrogen atoms, and one sulfur or oxygen atom as ring members, such as (but not limited to) 2-furyl, 3-furyl, 2-thienyl, 3-thienyl, 2-pyrrolyl, 3-pyrrolyl . -thiazolyl, 4-thiazolyl, 5-thiazolyl, 2-imidazolyl, 4-imidazolyl, 1,2,4-oxadiazol-3-yl, 1,2,4-oxadiazol-b5-yl, 1,2,4-thiadiazole -Z-yl, 1,2,4-thiadiazol-b-yl, 1,2,4-triazol-3-yl, 1,3,4-oxadiazol-2-yl, 1,3,4-thiadiazol-2 -yl and 1,3,4-triazol-12-yl; nitrogen-linked 5-membered heteroaryl containing one to four nitrogen atoms or benzofused nitrogen-linked 5-membered heteroaryl containing one to three nitrogen atoms: 5-membered heteroaryl groups which in addition to of carbon atoms, may contain from one to four nitrogen atoms or from one to three nitrogen atoms as ring members, and in which two adjacent carbon ring members or one nitrogen ring member and one adjacent carbon ring member may be bridged through a buta-1,3-diene-1,4-diyl group in which one or two carbon atoms may be replaced by nitrogen atoms, and these rings are attached to the skeleton through one of the nitrogen members of the ring, for example (but not limited to) 1-pyrrolyl, 1-pyrazolyl, 1,2,4-triazol-1-yl, 1-imidazolyl, 1,2,3-triazol-1-yl and 1,3,4-triazol-1-yl; b-membered heteroaryl containing from one to four nitrogen atoms: b-membered heteroaryl groups which, in addition to carbon atoms, may contain from one to three or from one to four nitrogen atoms as ring members, for example (but not (but not limited to) 2-pyridinyl, 3-pyridinyl, 4-pyridinyl, 3-pyridazinyl, 4-pyridazinyl, 2-pyrimidinyl, 4-pyrimidinyl, 5-pyrimidinyl, 2-pyrazinyl, 1,3,5-triazin-2-yl , 1,2,4-triazin-3-yl and 1,2,4,5-tetrazin-3-yl; benzofused 5-membered heteroaryl containing one to three nitrogen atoms or one nitrogen atom and one oxygen or sulfur atom: for example (but not limited to) indol-1-yl, indol-2-yl, indol-3-yl , indol-4-yl, indol-5-yl, indol-b-yl, indol-7-yl, benzimidazol-1-yl, benzimidazol-2-yl, benzimidazol-4-yl, benzimidazol-5-yl, indazole -1-yl, indazol-3-yl, indazol-4-yl,

Co) indazol-5-yl, indazol-b-yl, indazol-7-yl, indazol-2-yl, 1-benzofuran-2-yl, 1-benzofuran-3-yl, 1-benzofuran-4-yl, 1-benzofuran-5-yl, 1-benzofuran-b-yl, 1-benzofuran-7-yl, 1-benzothiophen-2-yl, 1-benzothiophen-3-yl, 1-benzothiophen-4-yl, 1- benzothiophen-5-yl, 1-benzothiophen-b-yl, 1-benzothiophen-7-yl, 1,3-benzothiazol-2-yl, 1,3-benzothiazol-4-yl, 1,3-benzothiazol-5- yl, 1,3-benzothiazol-b-yl, 1,3-benzothiazol-7-yl, 1,3-benzoxazol-2-yl, 1,3-benzoxazol-4-yl, 1,3-benzoxazol-b- yl, -/1,3-benzoxazol-b-yl and 1,3-benzoxazol-7-yl; benzofused b-membered heteroaryl containing three nitrogen atoms each: for example (but not limited to) quinolin-2-yl, quinolin-3-yl, quinolin-4-yl, quinolin-5-yl, quinolin- b-yl, quinoline-7-yl, quinoline-8-yl, isoquinolin-1-yl, isoquinolin-Z-yl, isoquinolin-4-yl, isoquinolin-5-yl, isoquinolin-b-yl, isoquinolin-7- yl and isoquinolin-8-yl.

This definition also applies to heteroaryl as part of a compound substituent, eg, heteroarylalkyl, etc., unless otherwise specified.

Heterocyclyl: a three- to fifteen-membered, preferably three- to nine-membered, saturated or partially unsaturated heterocycle containing one to four heteroatoms from the group consisting of oxygen, nitrogen, and sulfur: mono , bi- or tricyclic heterocycles that contain, in addition to the carbon members of the ring, from one to three nitrogen atoms and/or one oxygen or sulfur atom, or one or two oxygen and/or sulfur atoms; if the ring contains more than one oxygen atom, they are not directly adjacent; for example (but not limited to) oxyranyl, aziridinyl, 2-tetrahydrofuranyl, 3-tetrahydrofuranyl, 2-tetrahydrothienyl, 3-tetrahydrothienyl, 2-pyrrolidinyl, 3-pyrrolidinyl, 3-isoxazolidinyl, 4-isoxazolidinyl, 5-isoxazolidinyl, 3- isothiazolidinyl, 4-isothiazolidinyl, 5-isothiazolidinyl, Z-pyrazolidinyl, 4-pyrazolidinyl, 5-pyrazolidinyl, 2-oxazolidinyl, 4-oxazolidinyl, 5-oxazolidinyl, 2-thiazolidinyl, 4-thiazolidinyl, 5-thiazolidinyl, 2-imidazolidinyl, 4-imidazolidinyl, 1,2,4-oxadiazolidin-3-yl, 1,2,4-oxadiazolidin-5-yl, 1,2,4-thiadiazolidin-3-yl, 1,2,4-thiadiazolidin-5-yl yl, 1,2,4-triazolidin-3-yl, 1,3,4-oxadiazolidin-2-yl, 1,3,4-thiadiazolidin-2-yl, 1,3,4-triazolidin-2-yl, 2,3-dihydrofur-2-yl, 2,3-dihydrofur-Z-yl, 2,4-dihydrofur-2-yl, 2,4-dihydrofur-Z-yl, 2,3-dihydrothien-2-yl, 2,3- dihydrothien-3-yl, 2,4-dihydrothien-2-yl, 2,4-dihydrothien-3-yl, 2-pyrroline-2-yl, 2-pyrroline-3-yl, 3-pyrroline- 2-yl, Z-pyrroline-Z3-yl, 2-isoxazolin-Z3-yl, Z-isoxazolin-Z3-yl, 4-isoxazolin-Z-yl, 2-isoxazolin- 4-yl, 3-isoxazolin-4-yl, 4-isoxazolin-4-yl, 2-isoxazolin-5-yl, 3-isoxazolin-5-yl, 4-isoxazolin-5-yl, 2-isothiazolin-3- yl, Z-isothiazolin-Z-yl, 4-isothiazolin-Z-yl, 2-isothiazolin-4-yl, Z-isothiazolin-4-yl, 4-60 isothiazolin-4-yl, 2-isothiazolin-5-yl , 3-isothiazolin-5-yl, 4-isothiazolin-5-yl, 2,3-dihydropyrazol-1-yl,

2,3-dihydropyrazol-2-yl, 2,3-dihydropyrazol-3-yl, 2,3-dihydropyrazol-4-yl, 2,3-dihydropyrazol-5-yl,

C,4-dihydropyrazol-1-yl, C,4-dihydropyrazol-3-yl, 3,4-dihydropyrazol-4-yl, 3,4-dihydropyrazol-5-yl, 4,5-dihydropyrazol-1-yl, 4,5-dihydropyrazol-3-yl, 4,5-dihydropyrazol-4-yl, 4,5-dihydropyrazol-5-yl, 2,3-dihydrooxazol-3-yl, 2,3-dihydrooxazol-3-yl, 2,3-dihydrooxazol-4-yl, 2,3-dihydrooxazol-5-yl, 3,4-dihydrooxazol-2-yl, 3,4-dihydrooxazol-3-yl, 3,4-dihydrooxazol-4-yl, 3,4-dihydrooxazole-

B-yl, 3,4-dihydrooxazol-2-yl, 3,4-dihydrooxazol-3-yl, 3,4-dihydrooxazol-4-yl, 2-piperidinyl, 3-piperidinyl, 4-piperidinyl, 1,3- dioxan-5-yl, 2-tetrahydropyranyl, 4-tetrahydropyranyl, 2-tetrahydrothienyl, 3-hexahydropyridazinyl, 4-hexahydropyridazinyl, 2-hexahydropyrimidinyl, 4-hexahydropyrimidinyl, 5-hexahydropyrimidinyl, 2-piperazinyl, 1,3,5-hexahydrotriazine 2-yl and 1,2,4-hexahydrotriazin-3-yl. This definition also applies to heterocyclyl as part of a complex substituent, eg, heterocyclylalkyl, etc., unless otherwise defined.

Leaving group: Zmi or 5m2 leaving group, e.g. chlorine, bromine, iodine, alkylsulfonates (-0O50O:2-alkyl, e.g. -OO502CH3, -0502CE3) or arylsulfonates (-O502- aryl, e.g. -OO5O02RI , -0502RIMEe).

Not covered are combinations that are contrary to the laws of nature and that could be ruled out by a person skilled in the art based on his/her professional knowledge. For example, cyclic structures having three or more neighboring oxygen atoms are removed.

Explanation of methods of preparation and intermediate compounds

Derivatives of heteroarylpiperidine and -piperazine of formula (Y) can be obtained using various techniques. First, the possible methods are schematically shown below.

Unless otherwise stated, the radicals are each as defined above.

Methods according to the present invention for obtaining compounds of formula (I), if necessary, are carried out using one or more reaction aids.

Suitable for the use of reaction aids, if necessary, are inorganic or organic bases or acid acceptors. They preferably include alkali or alkaline earth metal acetates, amides, carbonates, bicarbonates, hydrides, hydroxides or alkoxides, for example sodium acetate, potassium acetate or calcium acetate, lithium amide, sodium amide, potassium amide or calcium amide, sodium carbonate, carbonate potassium or calcium carbonate, sodium hydrogencarbonate, potassium hydrogencarbonate or calcium hydrogencarbonate, lithium hydride, sodium hydride, potassium hydride or calcium hydride, lithium hydroxide, sodium hydroxide, potassium hydroxide or calcium hydroxide, sodium methoxide, ethoxide, n- or i-propoxide, n-, i-, sec- or tert-butoxide or potassium methoxide, ethoxide, n- or i-propoxide, n-, i-, sec- or tert-butoxide; and also basic organic nitrogen compounds, for example, trimethylamine, triethylamine, tripropylamine, tributylamine, ethyldiisopropylamine, M,M-dimethylcyclohexylamine, dicyclohexylamine, ethyldicyclohexylamine,

M,M-dimethylaniline, M,M-dimethylbenzylamine, pyridine, 2-methyl-, 3-methyl-, 4-methyl-, 2,4-dimethyl-, 2,6-dimethyl-, 3,-dimethyl- and 3 ... ene (OBM) or 1,8-diazabicyclo|5.4.01-undec-7-ene (OB).

If necessary, the methods according to the present invention are carried out using one or more diluents. Practically all inert organic solvents are useful diluents.

They preferably include aliphatic and aromatic, optionally halogenated hydrocarbons such as pentane, hexane, heptane, cyclohexane, petroleum ether, gasoline, naphtha, benzene, toluene, xylene, methylene chloride, ethylene chloride, chloroform, carbon tetrachloride, chlorobenzene, and o-dichlorobenzene. , ethers such as diethyl ether and dibutyl ether, glycol dimethyl ether and diglycol dimethyl ether, tetrahydrofuran and dioxane, ketones such as acetone, methyl ethyl ketone, methyl isopropyl ketone and methyl isobutyl ketone, esters such as methyl acetate and ethyl acetate, nitriles such as acetonitrile and propionitrile, amides , such as dimethylformamide, dimethylacetamide, and M-methylpyrrolidone, as well as dimethylsulfoxide, tetramethylenesulfone, and hexamethylphosphoramide, and OMRI.

The temperatures of the reactions in the implementation of the methods according to the present invention can vary in a wide range. As a rule, the temperatures used are in the range between 0 C and 250 "C, preferably between 10 "C and 185 "C.

The reaction time varies depending on the development of the reaction and the reaction temperature, but is usually in the range of several minutes to 48 hours.

The methods according to the present invention are usually carried out at standard pressure. However, it is also possible to work at increased or reduced pressure.

To carry out the methods according to the present invention, the necessary starting substances are used in each case, as a rule, in approximately equimolar amounts. However, it is also possible to use one of the applied components in each individual case in relatively greater excess.

Method A

Scheme 1: Method A m-i 2-8 c

Ky Y mm rem -.O05 5 juf (UM Uvochgv

AOS one or Ach (in Z p more stages (in; (XXIM) 5 MU? and MY each denote functional groups acceptable for the formation of the target heterocycle OS, for example, aldehydes, ketones, esters, carboxylic acids, amides, thioamides, nitriles, alcohols, thiols, hydrazines, oximes, amidines, amidoximes, olefins, acetylenes, halides, alkyl halides, methanesulfonates, trifluoromethanesulfonates, boronic acids or boronates

As a rule, it is possible to obtain compounds of formula (I) from the corresponding compounds (XXIII) and (XXIM) with acceptable functional groups M/? and M/o (I) (see Scheme 1, Method A). Numerous methods of obtaining heterocycles are known from literary sources (see MO 2008/013622; SotrgeNepvime Neieegosusiis SPpetivighu moyo. 4-6, edyoge: A. A. Kaipy2kKu apa b. mm.

Veez, Regdatop Rgev55, Mem Hogk, 1984; SotrgeNepvime Neiegosusiis Spetivigu II, my. 2-4, eayogv:

A. V. Kainii2Ku, S. MU. VNeez apa E.E. bshimep, Regdatop Rgevv5, Mem/ MoiKk, 1996; That Spetiviga oh

Neiegosussis Sotroypav, eayog E. b. Tauiog, Mieu, Mem Moic; Vodaz SNnetivzmgu oi Satbop

Sotroipav, my. 2-4, EIvemivti, Mem Mogk; Zupipevziv, 1982, 6, 508-509; Teiganeagop, 2000, 56, 1057-1094).

Method B

Scheme 2: Method B

In-- - ' -8

In t (Pb) "Ov

Ж m At 7 u In the 1st UZH

Ma or UM, ha

And in AAU (year in (v'Z

ЗХ ev A» 5 (I) in (pa) (Ie)

Specific ways of obtaining compounds of the formula (Ie) from the corresponding compounds (III) by interaction with compounds (Ia) or (IIb) are shown in Scheme 2,

Alkenes and alkynes (Ia) and (IB) are commercially available or can be prepared from commercially available precursors using methods described in the literature (e.g., from ketones or aldehydes by Wittig or Horner-Wadsworth-Emmons olefination: Spec. Neu . 1989, 89, 863-927 and olefination according to Julia: Teymapedhop Iey., 1973, 14, 4833-4836; and

From olefination according to Peterson: U. Oha. Spent 1968, 33, 780; with the Bestmann-Ohira reagent:

Zupipeziz 2004, 1, 59-62).

A compound of the general formula (Ie) is obtained from an alkene of the general formula (Ia) or from an alkyne of the formula (IB) and a compound (II) using a cycloaddition reaction (see, for example, MO 08/013622 and 5upipeziv, 1987, 11, 998-1001) .

Method B is carried out in the presence of an acceptable base. Preferred bases are tertiary amines (eg, triethylamine), and alkali or alkaline earth metal carbonates (eg, potassium or sodium carbonate), bicarbonates, and phosphates.

Method B is preferably carried out using one or more diluents.

When carrying out method B, inert organic solvents (for example, toluene and hexane) are preferred. Water is also a possible solvent. Alternatively, method B can be carried out in the presence of an excess of alkene (Ia) or alkyne (PIB).

Processing is carried out using generally accepted methods. If necessary, compounds are purified by recrystallization or chromatography.

Method C

Scheme 3: Method C in'9 a) МН.ОН in? t N

My YAN chlorination is 0-0

M ha - zhk «o- SHCHA f5--khk UM x-a 1 1

A-I We are A-I. h (I r (r (IM) (n)

One of the ways of obtaining intermediate compound (III) from compound (IM) is shown in Scheme C (Method

WITH).

The compound of the general formula (II) is obtained by condensation of the aldehyde of the formula (IM) with hydroxylamine and subsequent chlorination (see, for example, UMO 05/0040159, UMO 08/013622 and Zupipeviv5, 1987, 11, 998-1001).

In method C, aldehyde (IM) and hydroxylamine are first reacted (Scheme 4, stage (a)).

The corresponding oxime is then subjected to chlorination in the presence of an acceptable chlorinating agent. The preferred chlorinating agents are M-chlorosuccinimide, Maosi, NSIO and chlorine. After stage (a) of method C, the reaction mixture can be processed using conventional methods or also converted directly in stage (B).

Method C is carried out using preferably one or more diluents. In step (a) of method C according to the present invention, preference is given to the use of protic solvents, for example, ethanol as a solvent. After the formation of the corresponding oxime from the compound (IM), the reaction mixture is diluted in step (B) with an additional solvent, for example, tetrahydrofuran, and then aqueous sodium hypochlorite is added. Chlorination can also be carried out by adding M-chlorosuccinimide to OME.

Processing is carried out using generally accepted methods. If necessary, the compounds can be used in the next step without preliminary purification.

The method of Yu

Scheme 4: Method Yu in? m -a-I 2-8! in those of XHU I

UM hm --90 U. UM Heo-av 1

A-I. M and one or A-I. or (i, more stages (i, (XXMI) (I) each MU" and M/2 are functional groups suitable for the formation of the target heterocycle C, for example, aldehydes, ketones, esters, carboxylic acids, amides, thioamides, nitriles, alcohols, thiols, hydrazines, oximes, amidines, amidoximes, olefins, acetylenes, halides,

Z alkyl halides, methanesulfonates, trifluoromethanesulfonates, boric acid or boronates

As a rule, it is possible to obtain compounds of formula (I) from the corresponding compounds (XXMI) and (XXM) with acceptable functional groups M/" and M/2, (I) (see Scheme 4, method 0). Numerous methods are known from literature sources obtaining heterocycles (see MO 2008/013622; Sotrgenepvzime Neiegosusiis Spetivigu mo!. 4-6, edyoge: A.V. KayiKu apa b. M.

Veez, Regdatop Rgevzv, Mem Moik, 1984; Sotrgepepvime Neiegosusiis Spetivigu II, Moi. 2-4, edyogv:

A. V. Kaipy2Ku, S. M. Veez apa E. RE. bshimep, Regdatop Rgez5, Mem/ MoiKk, 1996; Tne Spetiviga oi

Neiegosussis Sotroypav, eayog E. b. Tauiog, MUyieu, Mem Moi; Vodaz SNetivigu oi Satbop

Sotroipav, my. 2-4, EIvemivg, Mem/ MogkK).

Method E

Scheme 5: Method E o

Uk M to u ve MO sh- u MN, oh, V u lady

MM -- --- -і7 U M d-i" Z (MIN) Um , and (c) At 1 5 r (yar (ХХ) (ІЮ)

Mu? means chlorine, bromine, iodine, p-toluenesulfonyloxy or methylsulfonyloxy

Specific ways of synthesizing a compound of formula (II) from compounds (IX) with compounds (MI!) are shown in Scheme 5 (method E).

Thiocarboxamides (IX) obtained using methods known from the literature, for example, by thionation of the corresponding carboxamide using, for example, a reagent

Lavesson (M/O2008/013622, Ogd. 5upiip.Moi. 7, 1990, 372). α-Haloketones or corresponding equivalents (for example, p-toluenesulfonyloxy or methylsulfonyloxy) are also prepared using methods known from the literature (for example, see UMO2008/013622), (Scheme 6).

Scheme 6 5 -- 12 of my Shi OV Grinyar's reagent based on Heck ethylene, UZ

M or m o v? (c) o (XII) in (Xi) (X) dl s in 2 (a) mod:

UA In? (6) (MI!)

MUZ means M,M-dimethylamino, M-methoxy-M-methylamino or morpholin-1-yl

Thiazoles (I) are obtained by the synthesis of thiazole according to the Hanch method from thiocarboxamides (IX) and α-haloketones or the corresponding equivalents (MI) (see, for example, "Soptrgepepvime

Neiegosusiis Spetivigu", Regdatop Rgez5, 1984; my. 6, rade5 235-363, "SotrgeNepvime Neiegosusiis

SPetivigu II", Regdatop Rhevzv, 1996; my. 3, rade5 373-474 and the references given in it, as well as document UMO 07/014290).

Method E is carried out using preferably one or more diluents. When carrying out method E, inert organic solvents (for example, M,M-dimethylformamide and ethanol) are preferred.

If necessary, use an additional base, for example, triethylamine.

If necessary, compounds are purified by recrystallization or chromatography.

Method E

Scheme 7: Method E 2 : 2 sulization about Ya- in Ur in AI, vd; h-a-o-iI-d i" h-a-o-I-V

Whew! in" G Ve! d G (wdo (wd zo (Ia) (IB)

Amides (Ia), obtained by carrying out method E according to the present invention (Scheme 7) can be converted by methods described in the literature into the corresponding thioamides (IB)

(for example, Vioogdapis 5 Meadisipai Spetivigu Ieyegv5, 2009, 19(2), 462-468). This involves the interaction of a compound of formula (Ia) typically with phosphorus pentasulfide or 2,4-bis(4-methoxyphenyl)-1,3-dithia-2,4-diphosphetane 2,4-disulfide (Lavesson's reagent) (see Scheme 7, Method

IS).

Method E according to the present invention is carried out using preferably one or more diluents. The preferred solvents are toluene, tetrahydrofuran, 1,4-dioxane and 1,2-dimethoxyethane.

After completion of the reaction, compounds (IB) are isolated from the reaction mixture using one of the standard separation techniques. If necessary, compounds are purified by recrystallization or chromatography.

Method b

Scheme 8: Method b 11 Il v' y y v' li 24 m O /-y 2 4 n-m o x-a-o----8 o udo x-a-a----8

We (IM) t sh (vd i A (vu, (XI) (Ia)

MU" means OH, EN, SI, Vg or I

One of the ways of obtaining compounds of formula (Ia) from the corresponding compounds (XIII) with compounds (IM) is shown in Scheme 8 (method 05).

Compounds (IM) are either commercially available or can be prepared using methods described in the literature (see, for example, UMO 2008/091580, UMO 2007/014290 and UMO 2008/091594).

The compound of the general formula (Ia) can be synthesized analogously to the methods described in the literature (see, for example, UMO 2007/147336), by means of the condensation reaction of the compound of the corresponding general formula (XIII) with the substrate of the general formula (IM), where M/" means chlorine, fluorine, bromine or iodine, optionally in the presence of an acid/base scavenger.

At least one equivalent of an acid/base scavenger (for example, Hunig's base, triethylamine or commercially available polymeric acid scavengers) is used relative to the starting material of general formula (XIII). If the starting material is salt, at least two equivalents of acid scavenger are required.

Alternatively, a compound of formula (Ia) may also be synthesized from a corresponding compound of formula (Xi) with a substrate of formula (II) where M/" is hydroxyl in the presence of a condensing agent, similar to methods described in the literature (e.g. Teigapeagop, 2005, 61, 10827-10852, and the references described herein).

Acceptable condensing agents are, for example, peptide condensing reagents (eg, M-(3-dimethylaminopropyl)-N'-ethylsarbodiimide mixed with N-dimethylaminopyridine, M-(3-dimethylaminopropyl)-N-ethylsarbodiimide mixed with 1-hydroxybenzotriazole , bromotripyrrolidinophosphonium hexafluorophosphate, O-(7-azabenzotriazol-1-yl)-M,M,M',M'-tetramethyluronium hexafluorophosphate, etc.).

After completion of the reaction, compounds (Ia) are isolated from the reaction mixture using one of the standard separation methods. If necessary, compounds are purified by recrystallization or chromatography.

Method N

Scheme 9: Method H in dA-H o in

I-yaki from Z won (MI) ped h-a-o-iiv'

M Z chen - nn z U 4 Basis 1 (v'dr (Vr (MIi) (Id)

MUZ is a departing group

In A"-H, a hydrogen atom is attached through a nitrogen atom.

One of the ways of obtaining compounds of the formula (II) from the corresponding compounds (MII) with compounds (MI)

shown in Scheme 9 (method H).

The starting materials, (MI), in which M/!Z is a leaving group, can be prepared by methods described in the literature for compounds (M), (XMIIe) or (XII) (Figure 1) (see e.g. , mesylation: Ogdapis IenNeg5, 2003, 2539-2541; tosylation: URbO156601; halogenation: A!yzigaiyap doshigatai oi Spetivigu, 1983, 2095-2110). Usually, compounds of the formula (MI,

MIZ or chlorine) is obtained by processing from the amide of the formula (XII) and chloroacetyl chloride.

Compounds (M) in (Figure 1) are obtained similarly to method C with glycolic acid or hydroxyacetyl chloride with (Xi) (see, for example, MO 2007103187, UMO2006117521,

Vioogdapis 8 Medisipa! Spetivigu and eNegv, 2007, 6326-6329).

Figure 1 2 2 2 c c c

О -ккь О с-м т8-бм

Mo h-a-o-I-vV! Mo h-a-o-V' nm H-s-o-I2v! tso-/7 h )- h or 1 (M) (HMPe) (HP)

Use at least one equivalent of the base (for example, sodium hydride, potassium carbonate) in relation to the starting substance of the general formula (MI).

After completion of the reaction, compounds (Id) are isolated from the reaction mixture using one of the standard separation methods. If necessary, compounds are purified by recrystallization or chromatography.

Way

Scheme 10: Method 2 v" v Mol to A-M--U M -va-o-1:V! nk rusetolya A 5 a-90--8 ' (KHIM) No (v (Vr r (khy) ( Yes)

One of the ways of obtaining compounds of the formula (Ic) from the corresponding compounds (XIII) with compounds (XIM) is shown in Scheme 10 (method I).

A compound of the general formula (II) can be synthesized similarly to the methods described in the literature (see, for example, UMO 2009/055514), by means of a condensation reaction of a compound of the corresponding general formula (XII) with a substrate of the general formula (ХИМ), optionally in in the presence of an acid/base scavenger, for example, triethylamine, 1,8-diazabicyclo|5.4.Fundec-7-ene, or Hunig's base.

After completion of the reaction, compounds (Ic) are isolated from the reaction mixture using one of the standard separation methods. If necessary, compounds are purified by recrystallization or chromatography.

Method U

Scheme 11: Method .) 2 N in Mt

Like A-M after -M h-a-o-I:vV! in? MD a-90---8 years old 1 in (in Z r

ЗB (ХУ) (ia)

Mu" means chlorine or imidazol-1-yl

One of the ways to obtain compounds of formula (4) from the corresponding compounds (XMa) or (XM) (see Figure 2) with compounds (XMI) is shown in Scheme 11 (method U).

Figure 2

2 2

U -kf 2 and U. -kh 2 and mm, x-a-o-v U-M, x-a-o--v soch t (Vr M (in (KHMa) (KHMUB)

The starting materials, carbamoyl and thiocarbamoyl chlorides of the formula (XMa), can be prepared by methods described in the literature for compounds (XII) (see, for example,

Temaneagop, 2008, 7605; midges of Ogdapis Spetivigu, 2004, 3787; Choitai oi Ogdapis Spetivigu, 1983, 4750; Eigoreap doigpa! oi Ogdapis Spetivigu, 2006, 1177). Usually, compounds of formula (Xma) are obtained by processing from amines of formula (XIII) and phosgene, thiophosgene or their equivalents.

Alternative starting materials, carbamoyl- and thiocarbamoyl-imidazoles of the formula (CMB), can be prepared using methods described in the literature (see, for example,

Temaneydtop I eyeg5, 2008, 5279; Themepagedtop, 2005, 7153). Usually, compounds of the formula (HMB) are obtained by processing from amines of the formula (XIII) and 1,1"-carbonyldiimidazole or 1,1'-thiocarbonyldiimidazole.

The method is carried out optionally in the presence of an acceptable acid acceptor.

Compounds (4) obtained by carrying out method .) according to the present invention in some cases can alternatively also be obtained without the use of an acid acceptor, as the corresponding acid chlorides KI4)-NSII. If necessary, compounds (Id) are isolated using generally accepted methods.

After completion of the reaction, compounds (4) are isolated from the reaction mixture using one of the standard separation methods. If necessary, compounds are purified by recrystallization or chromatography.

Method K

Scheme 12: Method of Removal of KE of the 4th protective group - she, behind Protective Corpses - 8-sV (ХУ them)

Uub stands for acetyl, C1-C4-alkoxycarbonyl, benzyl or benzyloxycarbonyl

One of the ways of obtaining compounds of the formula (XIII) from the corresponding compounds (HMI) is given in

Scheme 12 (method K).

From the compound of the formula (XMII) is converted into the compound of the formula (XIII) using suitable methods for removing protective groups described in the literature ("Rgoyesiime Sgopyr5 ip Ogdapis

Zupipeziv"; Tpeodoga MU. Steepe, Reieg s. M. MUtsiv; UiPeu-Ipiegzsiepse; Tpiga Edyop; 1999; 494- 653). tert-Butoxycarbonyl and benzyloxycarbonyl protective groups can be removed in an acidic medium (for example, using hydrochloric acid or (trifluoroacetic acid). Acetyl protecting groups can be removed under basic conditions (eg, using potassium carbonate or cesium carbonate). Benzyl protecting groups can be removed hydrogenolytically by treatment with hydrogen in the presence of a catalyst (eg, palladium on activated carbon).

After completion of the reaction, compound (XII) is isolated from the reaction mixture using one of the standard separation techniques. If necessary, the compounds are purified by recrystallization or chromatography, or, if desired, also used in the next step without prior purification. It is also possible to isolate the compound of general formula (XII) as a salt, for example as a salt of hydrochloric acid or trifluoroacetic acid.

Method I

Scheme 13: Method 11 2 1 in? m - 9-1 -Mon-8 in? in Iz (XHU) you are 2 years old

MAM hmm --- - and 5 MAM h-a-d-I-B

We are one or Y (in Z more stages (in Z (XXI!) (HMI)

Mu stands for acetyl, C1-C6-alkoxycarbonyl, benzyl or benzyloxycarbonyl

MUL and M/2 each denote functional groups acceptable for the formation of the target heterocycle as indicated above.

As a rule, it is possible to obtain an intermediate compound (XMII) from the corresponding compounds (XXII) with compounds (XXM). Method I (Scheme 13) was carried out similarly to method O (Scheme 4).

The method of M

Scheme 14: Method M o. 2 M, 5A

M in 2 in? Mo id

MN, (in) in: Street to

M-M drinking M

With (MY) M-M "and (c) 1 5 r (Vr (XXI) (KHUpa)

Mu? means chlorine, bromine, iodine, p-toluenesulfonyloxy or methylsulfonyloxy,

Uub stands for acetyl, C1-C4-alkoxycarbonyl, benzyl or benzyloxycarbonyl

Other ways of obtaining the intermediate compound of the formula (XM) from the corresponding compounds (XXI) are shown in Scheme 14 (method M). Compounds (XXI) are either commercially available or can be prepared using methods described in the literature (see, for example, UMO 2008/013622 and UMO 2007/014290). Method M was carried out similarly to method E (Scheme 5).

The method of M

Scheme 15: Method M vd n-achZo-I-i v?

XIX

MA-M we - 5259595 zhfUuvm sto-i-v'

Basis (jar (jar (XX) (XM)

Ce: a piperidine radical attached through a nitrogen atom or a carbon atom,

Mub means acetyl, C 1 -C 6 -alkoxycarbonyl, benzyl or benzyloxycarbonyl,

M/" means bromine, iodine, methylsulfonyloxy or trifluoromethylsulfonyloxy

The compound of the general formula (XMIIv) can be synthesized similarly to the methods described in

From the literature by means of a condensation reaction of a compound of the corresponding general formula (XX) with a substrate of the general formula (XIX), optionally in the presence of a base (Scheme 15, method M). (See, for example, for condensation reactions in the presence of 2p/Ra: M/o 2008/147831, UMO 2006/106423 (pyridine), ZpaKezreage, MU. S. eig a. Set. Vioi. Ota Oevzidp 2008, 71, 97- 105 (pyrimidine derivatives), Raziettak, A. ei and I. Wiooga. Med. Spec. I ei. 2008, 18, 994-998 (diazines);

Soiegidde, V. M.; VePo, b. 5.; I epeg, A. Temaneadgop I eyii. 2009, 50, 4475-4477; Vaspy, T., Neizeg, 5.

Apdem Spent Yiyi. Hey. 2001, 40, 3184-3185. (thiazoles); for nucleophilic substituents: U/O 2008/104077; MO 2006/084015 (M-substituted pyrazoles).

For nucleophilic substitutions, at least one equivalent of the base (for example, sodium hydride, potassium carbonate) is used in relation to the starting substance of the general formula (XX).

After the completion of the reaction, compounds (XMIIb) are isolated from the reaction mixture using one of the standard separation methods. If necessary, the compounds are purified by recrystallization or chromatography, or can also, if desired, be used in a subsequent step without prior purification.

Method O

Scheme 16: Method O mi-eo-i-Vv' in. (XXMIII) VYM 2 4

Mm-Mm MN - - --:: -5 MAM, M-a:O-I-V

M The basis of chi (vr (in (XXIX) (HMIis)

Ce: piperazine radical attached through a carbon atom

Mu stands for acetyl, C1-C6-alkoxycarbonyl, benzyl or benzyloxycarbonyl

MU8 means bromine, iodine, methylsulfonyloxy or trifluoromethylsulfonyloxy

The compound of the general formula (ХМІІС) can be synthesized similarly to the methods described in the literature (see, for example, for nucleophilic substituents: Gi, S. 5., Veiaig, Y., Mtsau, «. ei ai

Viogd. Honey. Spent Gay. 2009, 19, 5214-5217; MO 2008/062276; for condensation reactions in the presence of copper: Mep, M. 5. S.; MMedetap, R. E. Teigapedhop Gen. 2006, 47, 6011-6016; for condensation reactions in the presence of palladium: UMO 2008/061457) by means of condensation reactions of a compound of the corresponding general formula (XXIX) with a substrate of the general formula (XXIII), optionally in the presence of a base (Scheme 16, method 0).

Use at least one equivalent of the base (for example, sodium hydride, potassium carbonate) in relation to the starting substance of the general formula (XXIX).

After the completion of the reaction, compounds (XMIIc) are isolated from the reaction mixture using one of the standard separation methods. If necessary, the compounds are purified by recrystallization or chromatography, or can, if desired, also be used in a subsequent step without prior purification.

The method of R

Scheme 17: Method P 2 we-I1--B! в в: вой- з (XXI!) !

М-М хХ-ам --е3ей3й3й3й53535252 5252 З 5 53 мМ 0 х-а-о-иив! One or more stages

Mu stands for acetyl, C1-C6-alkoxycarbonyl, benzyl or benzyloxycarbonyl

MU? and WE each represent functional groups suitable for the formation of the target heterocycle as indicated above.

As a rule, it is possible to obtain the intermediate compound (XMII) from the corresponding compounds (XXMII) and (XXI). Method P (Scheme 17) was carried out similarly to method A (Scheme 1).

Method C

Scheme 18: Method 0

Ye Bu I 0 | When VA;

Ku M still Tv» KA M zh rya Kk schem, ho or Me, o ( | V- o. (8 IA a Hna)

In (Huna)

UNI (c)

Uub stands for acetyl, C1-C4-alkoxycarbonyl, benzyl or benzyloxycarbonyl

Specific ways of obtaining the intermediate compound (ХМиІІа) from the corresponding compounds (ХМІІІ) are given in

Scheme 18 (method 9). Starting substances of the formula (ХМІІІ) can be obtained using methods described in the literature (see, for example, UMO 2008/013622), and method 0 was carried out similarly to method B (Scheme 2).

The newest compounds are the compounds of the formula (MII), in?

Oh and-- with Y | ah ah!

M. U

(in (MI) and their salts, metal complexes and M-oxides, in which the symbols M/Z, B2, X, c, 0.12, B, Vo and p have the general, preferred, more preferred or most preferred definition.

The newest compounds are compounds of the formula (KhMIa), 2 (o) 2

In IZ 1

H M UZH, in here (vi

M-M, ha 10 (Ar (HMiIa) for example, (HMIIIU, oh how!

M v M "3-0

WITH

(XM) and their salts, metal complexes and M-oxides, in which the symbols Me, X, C, 12, p, B", Be, Do and Ko? have the above general, preferred, more preferred or most preferred definitions.

The newest compounds are compounds of the formula (XiIPa),

2 2

M in? lah n-M ha

We are 10 (Vr (Khsha) for example, (Khpib), 2

IN

M is not - (HINB) and their salts, metal complexes and M-oxides, in which the symbols X, 12, p, C, B", B, B" and 5 B"? have the general, preferred, more preferred or most preferred definitions set forth above.

The invention also relates to a composition for combating unwanted microorganisms containing at least one heteroarylpiperidine and -piperazine derivative according to the present invention.

The invention also relates to a method for combating unwanted microorganisms, which is characterized by the fact that heteroarylpiperidine and -piperazine derivatives according to the present invention are applied to microorganisms and/or to their habitat.

In addition, the invention also relates to seed material that has been treated with at least one heteroarylpiperidine and -piperazine derivative according to the present invention.

Ultimately, the invention relates to a method of protecting seed material from unwanted microorganisms by using seed material treated with at least one derivative of heteroarylpiperidine and -piperazine according to the present invention.

The substances according to the present invention have a powerful bactericidal activity and can be used to combat unwanted microorganisms such as fungi and bacteria, in crop protection and in the protection of materials.

Derivatives of heteroarylpiperidine and -piperazine of the formula (I) according to the present invention have very good fungicidal properties and can be used in crop protection, for example, to fight Riaztoaiorpogotuseiez, Ootuseiez, SPNuiiaiotuseie5, 7udotuseiev,

Avsotuseyev, Vazidiotuseyev and Oeshegotuseyev5.

Bactericides can be used to protect plants, for example, to fight

Rzepdotopadaceae, NPigoriaceae, Epiegobasieiiaceae, Sogupebasiegiaceae and 5igeriotuseiaceav.

Fungicidal compositions according to the present invention can be used to inhibit phytopathogenic fungi for therapeutic or prophylactic purposes. Thus, the invention also relates to therapeutic and prophylactic methods of combating phytopathogenic fungi by using active components or compositions according to the present invention, which are applied to seed material, a plant or parts of a plant, to fruits or soil in which plants are grown.

The compositions for combating phytopathogenic fungi for plant protection according to the present invention contain an effective but non-phytotoxic amount of the active components according to the present invention. The expression "effective but non-phytotoxic amount" means an amount of a composition according to the present invention that is sufficient to control a fungal disease of a plant in a satisfactory manner, or to completely suppress it, but at the same time does not cause any significant symptoms of phytotoxicity. As a rule, the consumable quantity can vary within a relatively wide interval. It depends on several factors, for example, on the fungi to be combated, the plant, the climatic conditions and the components of the compositions according to the present invention.

According to the present invention, it is possible to process whole plants or parts of plants. Plants in this document mean all plants and plant populations, such as desirable and undesirable wild and cultivated plants (including naturally occurring cultivated plants).

Cultivated plants can be plants obtained by traditional methods of cultivation and optimization, or by methods of biotechnology and genetic engineering, or a combination of these methods, including transgenic plants, and including plant varieties protected and unprotected by law

Zo on the protection of varieties. Plant parts include all above- and below-ground plant parts and organs such as shoot, leaf, flower and root, examples of which include leaves, needles, stems, trunks, flowers, fruits and seeds, roots, tubers, rhizomes. Plant parts also include the marketable product of the crop and vegetative and generative material for propagation, such as petioles, tubers, rhizomes, offshoots, and seeds.

According to the present invention, the plants that can be processed include the following: cotton, flax, grapes, fruit crops, vegetable crops, such as Kozaseae 5yr. (for example, fleshy seed crops such as apples and pears, but also stone fruit crops such as apricots, cherries, almonds and peaches, and berry crops such as strawberries), Kirevsioida 5yr.,

Uydiapdaseae sr., Veishiaseae 5y., Apasagaiaseae 5y., Radaseae 5y., Mogaseae s5r., OIsaseae sr.,

Asiipidaseae zr., Iashgaseaye v5r., Myvzaseae 5r. (e.g. banana trees and banana plantations), Cybiaceae 5y. (e.g., coffee tree), Tpeaseae 5yr., 5(exicisiaeeae 5yr., Kshaseaee 5yr. (e.g. lemons, oranges and grapefruit); ZoIIiapaseeae 5yr. (e.g. tomatoes), I Paseae 5yr., Abiegaseae 5yr. (e.g. lettuce), StbreiPegae 5 years, Stysiiegae 5 years, Speporoadiaseae 5 years,

Sysygriaseae 5 years. (for example, a cucumber), AIaseae 5 years. (for example, leek, spring onion),

Rarely propagates for 5 years. (for example, peas); main agricultural crops, such as SoOgatipeaye 5yr. (e.g. corn, grassland crops, grain crops such as wheat, rye, rice, barley, oats, millet and triticale), Avivegaseae 5y. (for example, sunflower), Vgazzisaseae 5yr. (for example, white cabbage, red cabbage, broccoli, cauliflower, Brussels sprouts, Chinese cabbage, kohlrabi, radish and oilseed rape, mustard, horseradish and watercress), Rarasaye 5 years. (for example, beans, peanuts), Rariijopaseae 5 years. (for example, soybeans), ZoYiIapaseae 5 years. (for example, potatoes), Speporodiaceae 5 years. (for example, sugar beet, fodder beet, leaf beet, table beet); useful plants and decorative plants in parks and forests; and genetically modified types of each of these plants.

Non-limiting examples of pathogens of fungal diseases that can be treated according to the present invention include: diseases caused by pathogens of true powdery mildew, for example, species of the genus Vištegia, for example, Vištegia dgatipie; species of the genus Rodozrpayega, for example, Rodozrpayega

Ieisoigispa; species of the genus Zrpaegoipesa, for example, Zrpaegoiyesa shiidipea; species of the genus Opsipshtia, for example, Opsipsha pesaiog; diseases caused by pathogens of rust diseases, for example, species of the genus

Sutpozrogapdisht, for example, Sutpozrogapdiit 5abripae; species of the genus Neptiieia, for example

Netiyeiia mabviaigih; species of the Rpakorzoga genus, for example, Rpakorzoga raspugtpigi or Rpakorzoga teirotiae; species of the genus Rissipia, for example, Rissipia hesopaia, Rissipia dgatipie or Rissipia 5gioptiv; species of the genus Ogotusev, for example, Ogotusez arrepadisciagiv5; diseases caused by pathogens from the Ootuseiyep group, for example, by species of the Airido genus, for example, Airido sapadida; species of the genus Vgetia, for example, Vgetia

Iasiisaye; species of the genus Regopozroga, for example, Regopozroga rizi or R. Bgazzisaye; species of the genus

Rpuorpiypoga, for example, RPuyuorpiyyoga ipieziap5; species of the Riaztoraga genus, for example

Riaztoraga miisoYa; species of the genus Rzheydoregopozroga, for example, Rzheydoregopozroga pitiiy or

Rzepydoreopozroga sirepvi5; species of the Ruiyisht genus, for example, Ruipisht and Kitit; leaf spotting and wilting diseases caused, for example, by species of the genus Ayegpagia, such as AcKegpagia zoiapi; species of the genus Segsozroga, for example, Segsozroga BeiisoiYia; species of the genus SiIadiozhrogit, for example, Siadiozrogicht sisitegipit; species of the genus SosPiyoroish5, for example, SospioBboyiSh5 zayimy5; (conidial form: Ogesnviega, sub:

Neitipipozrogisht) or SospiBoYi5 ptiuabeapie; species of the genus SoPeiohispyt, for example

SoPeyuktispyt Ipaetshyapisht; species of the genus Susiosopichsht, for example, Susiosopicht oIeadipit; species of the genus Oiarogipe, for example, Oiarogiye siigi; species of the genus Eilipoe, for example, Eilipoe Tamusetsia; species of the genus (Ioeozrogisht, for example, cSiIoeozrogisht PIaeiiysoiog; species of the genus SiIotegeiPa, for example,

Siotegeya sipdshiaya; species of the genus Siidpagaia, for example, Spidpagaia bBidueiii; species of the genus

IHeriozrpaegia, for example, Herioz5rpaietia tasshap5; species of the genus Madparogiye, for example,

Madparogiye adgyzea; species of the genus Misgodospisht, for example, Misgodospisht pimaie; species of the genus

Musozripaegeia, for example, MusozrpaegePye dgatipisoia, Musozrpaegeiia agaspidisoia or

Musozrpayegeiia yiepviv; species of the genus Rpaeozrpaegia, for example, Rpaeozrpaegia podogyt; species of the genus

Rugeporpoga, for example, Rugeporpoga iege5 or Rugeporpoga igyisi herepiiz; species of the genus Cathyiagia, for example, Cathyiagia soPo-sudpi or Cathyiagia ageoia; species of the genus KPpupspozrogisht, for example,

Kpupspozrogitst z5esaiie; species of the genus Zeriogia, for example, Zeriogia aria or Zeriogia Iusoregvisi; species of the genus 5iadopozroga, for example, Ziadopozroga podogyt; species of the Turpsha genus, for example,

Turpshia ipsagpada; species of the genus Mepitsipgia, for example, Mepishygia ipaedchaiiv; 60 diseases of roots and stems caused, for example, by species of the genus Sogiishht,

for example, Sopisisht dgatipeagyt; species of the genus Ryzagisht, for example, Ryzagisht ohuzrogyt; species of the genus Saeshthappotuse5, for example, Saetsthappotuse5 dgatipie; species of the genus Riaztodiorpoga, for example, Riazitodiorpoga Bbgazzisaye; species of the KPi2osiopia genus, for example, Kpi2osiopia 50iapi; species of the genus Zagosiadiyt, for example, Zagosiadisht ogugae; species of the genus Zsiegoisht, for example, ZsiegoiiCht ogulaye; species of the genus Taresia, for example, Taresia asshopti; species of the genus TPpiveiamiorzi5, for example,

ТНпиеииамиорвзив Bavisoia; ear and panicle diseases (including corn cobs) caused, for example, by species of the AKegpagia genus, for example, AKegpagia 5rr.; species of the genus Azregodiyn5, for example, AzregoyShiv5

Pami5; species of the genus Siadozrogisht, for example, Siadozrogicht siadozrogioide5; species of the genus Siamiserv, for example, Siamicer5 rygrigea; species of the genus ERizagisht, for example, Ryzagisht syitogyt; species of the genus (sibregeiPa, for example, sSibregeia 7eae; species of the genus MopodgarpeiPa, such as, for example,

Mopodharpeigia pimaii5; species of the genus Ziadopozroga, for example, Zadopozroga podogyt; diseases caused by cephalosporins, for example, species of the genus

Zrpaseoipesa, for example, 5rpaseIyuiesa heyiyapa; species of the genus TPSheia, for example, TiPeiba sagie5 or

Tsheya sopygomegza; species of the genus ShOgosuvii, for example, Ogosuvii ossiyya; species of the O5yado genus, for example, O5Nado pida; fruit rot, which is caused, for example, by species of the genus Azregdiyya5, for example, Azregoyy5

Pami5; species of the genus Voiguiih, for example, Voiguiz sipegeach species of the genus RepisySisht, for example

Repisiyisht echrapsite or Repisiyisht rigrigodepit; species of the genus 5siegoiipia, for example, 5siegoiipia 5cIegoiiogyt; species of the genus Mepisiisht, for example, Mepisiisht aIroaigit; diseases originating from rotting and wilting of seeds and soil, as well as diseases of seedlings caused by, for example, species of the genus AKegpagia, for example AKegpagia Bgazvisisoia; by type of genus by type of genus Arpapotusev5, for example, Arpapotuse5 esheispe5; a species of the genus Azsospuga, for example, Azsospuia Iepiie; by the genus Azregoya5, for example, Azregoya5 Pama5; kind of genus

SiIadozrogist, for example, SiIadozrogist Ppegragit; species of the genus SospPiyoBoYish5, for example

Sospioroishye zaiimy5 (conidial form: Ogesy5iegta, Bup: NeiYitipipozrogishyt); kind of genus

SoPefihispyt, for example, SoPeifoihispyt sossode5; by the genus ERizagisht, for example, Ryzagiit sy!togyt; type of genus SirregePa, for example, sSirregeia 7eaee; a species of the genus Masgorpotypa, for example, Masgorpotypa rpaseoiypa; a species of the genus Misgodospisht, for example, Misgodospisht pimaye; a species of the genus Mopodharpeia, for example, Mopodharpeia pimaii5; a species of the genus Repisiysht, for example

Repisiysht echrapsite; species of the genus Rpota, for example, Rpota Ipdat; a species of the genus Rpotorbviv, for example, Rpotorz5ziv zdidae; species of the genus Rpuiorpipoga, for example, Rpuiorpiivpoga sasiogit; species of the genus Rugeporpoga, for example, Rugeporpoga dgatipea; species of the genus Rugisciagia, for example

Rugisciagia ogulaee; by the genus Ruipisht, for example, Ruiyisht iyShtit; species of the genus KpPi2osiopia, for example, KPi2osiopia 5oYapi; by the genus KPi2ory5, for example, Kpihory5 ogu7ae; by the genus zsiegoiishSht, for example, Zsiegoisht goibi; a species of the genus Zeriogia, for example, Zeriogia podogyt; a species of the genus Turpsha, for example, Turpshia ipsagpada; a species of the genus Mepisiiysht, for example, Mepisnit danpiiae; cancers, galls (growths) and witches' broom caused by, for example, species of the genus Mesigia, such as Mesigia diepa; wilt diseases caused by, for example, species of the genus Mopiiipia, for example, Mopiiipia

Iaha; deformations of leaves, inflorescences and fruits, which cause, for example, species of the genus Jehovahviaiicht, for example, Ehoravzidisht mehap5; species of the genus Tarpgipa, for example, Tarpgipa deFoptapv; degenerative diseases of woody plants, which are caused, for example, by species of the genus Ezsa, for example, RIPaetopieMia siatudozoroga, RPpaeoasgetopisht aIeorpiisht or Rotyirogia teayetapea; species of the genus Sapodepgta, for example, Sapodepta Bropipepze; flower and seed diseases caused by, for example, species of the genus Voiguii5, e.g.

Voiguii5 sipegea; diseases of plant tubers, which cause, for example, species of the genus KPi2osiopia, for example,

КПпи2осиопиа 5оиапи; species of the NeiItipipozrogisht genus, for example, NeiItipipozrogisht 5o01api; diseases caused by bacterial pathogens, for example, species of the genus Hapitopopav, for example, Hapiyotopach satrebvigiz rm. species of the genus Rbzetspdotopav5, for example,

Rzepydotopaz zugipday ru. Iaspgutape; species of the genus Egm/pia, for example, Egm/ipia atuiomoga. mainly the following diseases of soybeans can be combated: fungal diseases of leaves, stems, pods and seeds, such as, for example, spots on the leaves caused by the species of the genus AiMegpagia 5res. ayyap5 epiizvzita, Apiygaspose (SoPeshihispyt dioeozrogoide5 detaiysht mag. igypsaisht), zeriogia diusipe5, leaf spots and wilting of leaves caused by a species of the genus Segsozroga Kikispii, wilting of leaves caused by a species of the genus 60 Spoapernoga ipiipairiiyega Shizroga (bup.)) , spots on the leaves caused by the species of the genus

Rasishiornoga diusipe5, powdery mildew caused by the species Regopozroga tapzpygis, wilt caused by the species Ogespziega diusipe, banded leaf spots caused by the species Segsozroga z5d|ipa, leaf spots caused by the species

And eriozrpaegiiiipa igioiii leaf spots caused by a species of the genus RpPuiobiysia 5od)|aesoia, wilting of pods and stems caused by a species of the genus RIotorzih 50iae, powdery mildew caused by a species of the genus Misgo5rpaiega ayibzhha, spots on a leaf caused by a species of the genus Rugepospaeia diusipe), wilting of aerial parts, leaves and plant tissues caused by the species of the genus KPi2osiopia 5o0Iap), rust caused by the species of the genus (Rpakorzoga raspugpigi, Rpakorzoga teirotia), crust-like spots caused by the species of the genus zrpaseiota diusipe5, wilting leaves caused by the species of the genus 5ietrPuiisht Boiguozit, point spots caused by the species of the genus Sogupezroga savzviisoia; fungal diseases of roots and stem bases caused by, for example, black root rot caused by the species Saipopesigia sgoiagiae, sclerotial rot caused by the species Mashorpotypa rpazeoiipa, wilt or rot, root rot and pod and crown rot caused by the species of the genus Rhyzagist ohuzrogyt, Ryzagist opposega5, Ryzagist zetiesiyt, ERizagicht ediizeii, root rot caused by species of the genera MusoiIeriodibsiv ectevigiz, Meosoztor5khroga mausiptesia, wilting of pods and stems caused by the species of the genus Oiarogiye rpazeiogyt, stem cancer caused by the species of the genus

Oiaropne rPpazeoogyt mag. satiumoga, rot caused by the species of the genus RPuiorpiyoga tedazrepta, brown stem rot caused by the species of the genus RPiaiornpoga dgedaia, rot caused by the species of the genus Ruiyisht arpapidegtaisht, Ruyisht igtedshiage, Ruyisht debraguapyt,

Rustisht ptugioguisht, Ruipicht shKitit, root rot, stem rot and death from excessive moisture caused by the species of the genus KpPi2osiopia 5oYapi, destruction of stems caused by the species of the genus Zsiegoiipia 5siegoyogit, southern sclerotial rot caused by the species of the genus Zsiegopia goiy5i, root rot caused by kind of genus

Tpieiiamiorvzi5 Bavzisoia.

Biologically active components according to the present invention also have a very good strengthening effect on plants. In this regard, they are suitable for mobilizing the plants' own forces to protect against damage by unwanted microorganisms.

З Under substances that strengthen plants (that induce resistance), in connection with the above, such compounds are understood that are able to stimulate the protective system of plants in such a way that the treated plants, upon subsequent inoculation with undesirable microorganisms, show long-term resistance to these microorganisms.

Unwanted microorganisms in this case should be understood as phytopathogenic fungi and bacteria. Substances according to the present invention can be used in such a way as to protect plants for a certain period of time after treatment from damage by the specified pathogens. The period of time during which protection occurs is, as a rule, from 1 to 10 days, preferably from 1 to 7 days after treatment of plants with biologically active substances.

The good tolerance of biologically active components by plants at concentrations necessary for combating plant diseases allows processing of aerial parts of plants, planting and seed material, and soil.

Biologically active components according to the present invention can be particularly successfully used to fight diseases in the cultivation of grapes and fruit crops, potatoes and vegetable crops, for example, especially against true powdery mildew caused by species of the genus Ootuseiyev, for example, Rpuoriivoga, Riazhtoraga, pseudoperonospora (Rzhepdoregopozroga ) and Ruipicht.

According to the invention, the active substances are also acceptable for increasing the yield. In addition, they are low-toxic and well tolerated by plants.

In some cases, the compounds according to the present invention can, in certain concentrations or consumption amounts, also be used as herbicides, antidotes, growth regulators or agents for improving the properties of plants, or as microbicides, for example as fungicides, bactericides, antiviral drugs (including compositions against viroids) or as compositions against MGO (Musoriazta-like organisms) and KO (Kiskebvia-like organisms). These compounds, if necessary, can be used as insecticides. They can also be used as intermediates and starting products for the synthesis of other active components.

Active substances according to the invention, if they are well tolerated by plants, have little toxicity in relation to warm-blooded animals and are well tolerated by the environment, are suitable for use for the protection of plants and plant parts, for increasing the harvested crop, for improving the quality of the harvested crop in rural areas in agriculture, in crop production, in animal production, in forests, in parks and recreation areas, in the protection of stored products and materials, and in sanitation. They are mainly used as compositions for crop protection. They are effective against species with normal sensitivity and resistant species, and against all or some stages of their development.

According to the present invention, the treatment of plants and parts of plants with active substances or compositions is carried out directly, or by acting on their environment, growing medium or storage premises by conventional processing methods, for example, by immersion, spraying, spraying, watering, steam treatment, fine-drop spraying, spreading, foaming, painting, scattering on plants, soaking, drip irrigation, application, injection, and in the case of propagating material, especially seeds, also by dry seed treatment, wet seed treatment, emulsion treatment, single or multilayer coating. Active substances can also be applied in ultra-small volumes, or the preparation of the active substance, or the active substance itself can be injected into the soil.

Active substances or compositions according to the invention can also be used in the protection of materials, to protect the technical material against damage and destruction by unwanted microorganisms, for example, fungi.

Technical materials in this context should be understood as inanimate materials that are prepared for use in industry. For example, technical materials that can be protected by active substances, according to the present invention, from changes and destruction under the action of microbes, are adhesives, glues, paper and cardboard, textile materials, leather, wood, dyeing materials and plastic products, lubricants - cooling liquids and other materials that can be affected or destroyed by microorganisms. Technical materials subject to protection also include parts of industrial installations, for example, cooling water circulation systems, which may be at risk as a result of the growth of microorganisms. Within the framework of this invention, technical materials mainly include adhesives, glues, paper and cardboard, leather, wood, paint materials, lubricating and cooling liquids and fluids - heat carriers, more preferably wood. Active substances or compositions according to the invention can prevent harmful effects such as rotting, decomposition, discoloration, discoloration or mold formation.

Ko) The method of combating unwanted fungi according to the invention can also be used to protect stored goods. Stored goods should be understood as natural substances of plant or animal origin, or products of their processing, which are of natural origin, and goods that require long-term protection. Stored goods of animal origin, such as plants or parts of plants such as stems, leaves, tubers, seeds, fruits, grains, may be protected immediately after harvesting or after processing by drying or drying, moistening, grinding, grinding, pressing or roasting Stored goods also include timber, both unprocessed such as construction timber, electric poles and fencing, or in the form of end products such as furniture. Stored goods of animal origin are, for example, hides, skins, furs and wool. Active substances according to the invention can prevent harmful effects such as rotting, decomposition, discoloration, discoloration or mold formation.

Microorganisms capable of causing the destruction or alteration of technical materials include bacteria, fungi, yeasts, algae, or slime organisms. Active substances, according to the invention, mainly act on fungi, especially mold fungi, fungi that stain and destroy wood (basidiomycetes), as well as on slime organisms and algae. Examples include species of microorganisms of the following genera: species of the genus AKegpagia, such as AKegpagia yepii5; species of the genus

AzregoiiPi5, such as Azregodiy5 podeg; species of the genus Spaeyutist, such as Spaeyutish dioro5it; species of the genus Sopiorpoga, such as Sopiorpoga rieiapa; species of the genus I epiipy5, such as Hepiiipy5 (dhipy5); species of the genus Repisiyshit, such as Repisiyyst diaisit; species of the genus Roiurogyv5, such as Roiurogyv5 megzisoiog; species of the genus Aipgeobravzidiit, such as A!ygeoravzidisht riiishiape; species of the genus Zsiegorpota, such as zsiegorpota riiuorpia; species of the genus Tgispodegta, such as Tgispodepta migide; species of the genus EzspPegispia, such as EzsPegispia soii; species of the genus Rzheidotopav, such as Rzendotopach5 aegidiposa; species of the genus Arpuosossiv5; such as Ziarpuiosossiv5 atsygetsv5.

The present invention also relates to a composition for combating unwanted microorganisms, containing at least one derivative of heteroarylpiperidine and -piperazine, according to the invention. They are mainly fungicidal compositions containing agriculturally suitable excipients, solvents, carriers, surfactants or fillers. According to the invention, the carrier is a natural or synthetic organic or inorganic substance with which the active substances are mixed or combined for better suitability, in particular, for application to plants or plant parts or seeds. The carrier, which may be solid or liquid, is generally inert and should be suitable for use in agriculture.

Suitable solid carriers include: for example ammonium salts and natural rock flours such as kaolins, aluminas, talc, chalk, quartz, attapulgite, montmorillonite or diatomaceous earth and synthetic rock flours such as highly dispersed silicic acid, oxide aluminum and silicates; suitable carriers for the granules include: for example, crushed and fractionated natural rock such as calcite, marble, pumice, sepiolite, dolomite, as well as synthetic granulates from flours of inorganic and organic materials, and granulates from organic material such as paper, sawdust, coconut shells, corn cobs and tobacco stalks; emulsifying and/or foaming agents include: for example, nonionic and anionic emulsifiers, such as polyoxyethylene fatty acid esters, polyoxyethylene fatty alcohol ethers, for example, alkylaryl polyglycol ethers, alkyl sulfonates, alkyl sulfates, aryl sulfonates, and protein hydrolysates; acceptable dispersants are non-ionic and/or non-ionic substances, for example, from the classes of ethers, alcohol-

POE and/or -POP, acid esters and/or POE POE, alkylaryl ethers and/or POE POE, adducts of fats and/or POE POE, derivatives of POE- and/or POE-polyol, adducts of POE- and/or POE- sorbitol or -sugars, alkyl or aryl sulfates, alkyl or aryl sulfonates, and alkyl or aryl phosphates, or corresponding PO-ether adducts. In addition, suitable oligomers or polymers are, for example, those derived from vinyl monomers, from acrylic acid . with formaldehyde.

Active substances can be transformed into conventional preparations, such as solutions, emulsions, powders for spraying, suspensions on a water and oil basis, powders, means for spraying, pastes, soluble powders, soluble granules, granulates for scattering, suspension-emulsion concentrates, natural substances impregnated with active substances, synthetic substances impregnated with active substances, fertilizers, as well as microcapsules in

From polymeric substances.

Active substances can be used by themselves, in the form of their preparations or forms obtained from them, such as ready-to-use solutions, emulsions, suspensions on an aqueous or oily basis, powders, powders for spraying, pastes, soluble powders, sprays, soluble granules, granules for spreading, suspension-emulsion concentrates, natural substances impregnated with active substances, synthetic substances impregnated with active substances, fertilizers, as well as microcapsules in polymeric substances.

Application is carried out in the usual way, for example, by watering, sprinkling, sprinkling, scattering, spraying, foaming, spreading, etc. Active substances can be applied by ultra-small volumes or the preparation of the active substance or the active substance itself can be injected into the soil. It is also possible to process seed material of plants.

Said preparations can be obtained by known methods of reg 5e, for example, by mixing the active substances with at least one common filler, solvent or diluent, emulsifying, dispersing and/or binding agent, or an agent that increases stickiness, a wetting agent, an agent that prevents wetting with water, if necessary, desiccants and UV stabilizers and, if necessary, dyes and pigments, antifoam agent, preservatives, secondary thickening agents, adhesives, gibberellins, as well as other additional substances.

The present invention includes not only ready-to-use preparations that can be used in suitable apparatus for treating plants or seeds, but also commercially available concentrates that are diluted with water before use.

Active substances, according to the invention, can be present both by themselves and in the form of (commercially available) preparations and when used in forms obtained from these preparations as a mixture with other (known) active substances, such as insecticides, attractants , sterilizers, bactericides, acaricides, nematicides, fungicides, growth regulators, herbicides, fertilizers, antidotes and/or semi-chemicals.

The auxiliary substances used can be those substances which are suitable for imparting certain properties to the composition itself and/or preparations obtained from it (for example, solutions for spraying, disinfection of seeds), such as certain technical properties and/or also certain biological properties Typical excipients include:

fillers, solvents and carriers.

Suitable excipients include, for example, water, polar and non-polar organic chemical liquids, for example from the classes of aromatic and non-aromatic hydrocarbons (such as paraffins, alkylbenzenes, alkylnaphthalenes, chlorobenzenes), alcohols and polyols (which may also be optionally substituted, esterified and /or esterified), ketones (such as acetone, cyclohexanone), esters (including fats and oils) and (poly)ethers, unsubstituted and substituted amines, amides, lactams (such as M-alkylpyrrolidones) and lactones, sulfones and sulfoxides (such as dimethyl sulfoxide).

Liquefied gaseous fillers or carriers are liquids which are gaseous at normal temperature and pressure, for example aerosol carrier gases such as halohydrocarbons, or also butane, propane, nitrogen and carbon dioxide.

Tackifying agents such as carboxymethyl cellulose, natural or synthetic polymers, in powder, granule or latex form, polymers such as gum arabic, polyvinyl alcohol and polyvinyl acetate, as well as natural phospholipids such as cephalins and lecithins, may be used in preparations. and synthetic phospholipids. Other additives can be mineral and vegetable oils.

If water is used as a filler, organic solvents can also be used as auxiliary solvents, for example. Suitable liquid solvents are essentially: aromatic compounds such as xylene, toluene or alkylnaphthalenes, chlorinated aromatic compounds and chlorinated aliphatic hydrocarbons such as chlorobenzenes, chloroethylenes or methylene chloride, aliphatic hydrocarbons such as cyclohexane or paraffins, such as petroleum fractions , alcohols such as butanol or glycol and their ethers and esters, ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone or cyclohexanone, highly polar solvents such as dimethylformamide and dimethyl sulfoxide, or also water.

Compositions according to the invention, in addition, may contain additional components, for example, surface-active substances. Suitable surfactants are emulsifiers and/or foaming agents, dispersing agents or wetting agents having ionic or nonionic properties, or mixtures of these surfactants. Examples of them are salts of polyacrylic acid, salts of lignosulfonic acid, salts of phenolsulfonic acid

Zo or naphthalene sulfonic acid, polycondensates of ethylene oxide with fatty alcohols or with fatty acids, or with fatty amines, substituted phenols (mainly alkylphenols or arylphenols), salts of sulfosuccinic esters, taurine derivatives (mainly alkyltaurates), phosphoric acid esters of polyethoxylated alcohols or phenols, fatty esters polyols and derivatives of compounds containing sulfates, sulfonates, and phosphates, for example, alkylarylpolyglycol ethers, alkylsulfonates, alkyl sulfates, arylsulfonates, protein hydrolysates, lignin-sulfite alkalis, and methylcellulose. The presence of a surface-active substance is necessary if one of the active substances and/or one of the inert carriers are insoluble in water and when the application is carried out in water. The ratio of surfactants.

Dyes such as inorganic pigments such as iron oxide, titanium oxide and Prussian blue, and organic dyes such as alizarin dyes, azo and metal phthalocyanine dyes, and trace amounts of nutrients such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc.

Other additives may be fragrances, mineral or vegetable, optionally modified oils, waxes and nutrients (including micronutrients) such as salts of iron, manganese, boron, copper, cobalt, molybdenum and zinc.

Additional components may include stabilizers such as antifreeze stabilizers, preservatives, antioxidants, light protectants, or other agents that improve chemical and/or physical stability.

If necessary, the presence of other additional components is also possible, for example, protective colloids, binders, adhesives, substances that increase stickiness, thixotropic substances, penetrants, stabilizers, sequestrants, complex-forming agents.

As a rule, active substances can be combined with any solid or liquid additive that is usually used for use in drugs.

Preparations, as a rule, contain between 0.05 and 99 wt. 95, 0.01 and 98 wt. 95, preferably between 0.1 and 95 wt. 95, more preferably between 0.5 and 90 wt. 95 active substances, most preferably between 10 and 70 wt. 95.

The drugs described above can be used in the method according to the invention to combat unwanted microorganisms, in which the derivatives of heteroarylpiperidine and -piperazine according to the invention are used against microorganisms and/or on their habitat. 60 The active substances according to the invention can also be used alone or in the form of their preparations, in a mixture with known fungicides, bactericides, acaricides, nematicides or insecticides, in order, for example, to extend the spectrum of action, or to prevent the emergence of resistance to them .

Suitable mixing components include, for example, known fungicides, insecticides, acaricides, nematicides or also bactericides (see also Rezviside Mapiai, 1448 ea.).

A mixture with other known active substances such as herbicides or with fertilizers and regulators, antidotes and/or semi-chemicals is also possible.

Application was carried out using standard methods suitable for the forms used.

In addition, the invention relates to a method of processing seed material.

Another aspect of the present invention relates, in particular, to seed material treated with at least one of the heteroarylpiperidine and -piperazine derivatives according to the invention. Seed material according to the invention is used in methods for protecting seed material from phytopathogenic harmful fungi. In these methods, at least one active substance according to the invention was used during seed treatment.

Active substances or compositions according to the invention are also acceptable for seed treatment. Most of the damage to the plant crop is caused by harmful organisms initiated by infection of the seed material during storage or after sowing, as well as during and after the germination of the plant seed. This phase is particularly critical because the roots and shoots of the growing plant are particularly sensitive, and even minimal damage can result in the death of the plant. Thus, there is great interest in the protection of seed material and plant germination through the use of appropriate compositions.

The control of phytopathogenic harmful fungi by treatment of plant seed material has been known for a long period of time and is subject to continuous improvement. However, the processing of seed material causes a number of problems that cannot always be solved in an acceptable way. For example, it is desirable to develop ways to protect seed material and

Ko) germinated plants, which do without, or at least significantly reduce, additional application of the composition for crop protection after sowing or after germination of plants.

It is also desirable to optimize the amount of the active substance used in such a way as to provide the best possible protection of the seed material and the sprouted plant from infection by phytopathogenic fungi, but without damaging the plant itself with the active substance used. In particular, the methods of seed treatment should also take into account the factor of own fungicidal properties of transgenic plants in order to achieve optimal protection of seed material and germinated plants with minimal consumption of the composition for crop protection.

The present invention thus also relates to a method of protecting seed material and germinated plants against the attack of animal pests and/or phytopathogenic harmful fungi by treating the seed material with a composition according to the invention.

The invention also relates to the use of the composition for treating seeds, according to the invention, to protect seeds and germinated plants from phytopathogenic fungi. In addition, the invention also relates to seed material that has been treated with a composition for protection against phytopathogenic fungi according to the invention.

Pest animals and/or phytopathogenic harmful fungi that damage plants after the emergence of seedlings are fought primarily by treating the soil and above-ground parts of plants with a crop protection composition. Due to concerns about the possible effect of the crop protection composition on the environment and the health of people and animals, measures are being taken to reduce the amount of active substances used.

One of the advantages of the presented invention is that due to the special systemic properties of the composition, according to the invention, the treatment of seed material with these compositions protects not only the seed material itself, but also plants from pests and/or phytopathogenic harmful fungi , which grow from it after germination. Thus, urgent treatment of plants during sowing or soon after it can be avoided.

The advantage is also that the active substances or compositions according to the invention can, in particular, be used for the treatment of transgenic seed material, in which case the plant growing from this seed is capable of expressing a protein that acts against pests. As a result of the treatment of such seed material with active substances or 60 composition according to the invention, only by the expression of a protein, for example, an insecticidal protein, it is possible to fight against some pests. Unexpectedly, in this case, an additional synergistic effect could be observed, which additionally increases the effectiveness in the protection against pest attacks.

The compositions according to the invention are suitable for the protection of seed material of any kind of plants used in agriculture, in greenhouses, in forests or in horticulture. In particular, it refers to the seed material of cereal crops (such as wheat, barley, rye, millet and oats), corn, cotton, soybeans, rice, potatoes, sunflowers, beans, coffee, beets (such as sugar beets and fodder beets), peanuts , vegetable crops (such as tomatoes, cucumbers, onions and lettuce), lawns and ornamental plants. Special importance is given to the processing of seed material of grain crops (such as wheat, barley, rye and oats), corn and rice.

As also indicated below, the treatment of transgenic seed material with active substances or compositions according to the invention is of particular importance. This refers to the seed material of plants containing at least one heterologous gene that provides expression of a polypeptide or protein having insecticidal properties. The heterologous gene in the transgenic seed material may originate, for example, from species microorganisms

Vasiyi5, REPi2obisht, Rzeidotopav, Zeitaiia, Tgispodegta, Siamirasieg, Sioti5 or Siosiadiit.

This heterologous gene is preferably derived from Vasilia 5 yr., in which case the gene product is effective against the corn borer (Engoreap taiele Brogeg) and/or the western corn beetle (Umeziegp taiile gooim'ogt). The heterologous gene is more likely to come from Vasiya5

Iipdiepviv.

Within the framework of the present invention, the composition according to the present invention is applied to the seed material by itself or in the form of a suitable preparation. The seed material is preferably processed in such a state that it is sufficiently stable to prevent damage during processing. In general, seed treatment can be done at any time between harvest and planting. Usually, seed material is used, which is separated from the plant and from cobs, husks, stems, shells, fibers or fruit pulp. So, for example, you can use seed material that, after harvesting, is cleaned and dried to moisture content

From less than 15 wt. 95. Alternatively, it is possible to use seed material which, after drying, has, for example, been treated with water and then dried again.

In general, when treating seed material, attention should be paid to the fact that the amount of the composition according to the present invention and/or the amount of other additional substances applied to the seed material is selected in such a way that it does not affect the germination of the seed material, or that the sprouts are not damaged plants from it. This should be especially taken into account in the case of active substances, which may exhibit phytotoxic effects at certain consumption quantities.

Compositions according to the present invention can be applied directly, that is, in the absence of the content of other components and without dilution. As a rule, preference is given to applying the composition in the form of a suitable preparation to the seed material. Suitable preparations and methods of processing seed material are known to specialists in this field and are described, for example, in the following documents: 05 4,272,417, 05 4,245,432, 05 4,808,430, 05 5,876,739, 05 2003/0176428, MO 2002/080675, MO 20182/02 28186.

The active substances suitable for use according to the present invention can be transformed into conventional preparations for impregnation of seed material, such as solutions, emulsions, suspensions, powders, foams, suspensions or other coating compositions for seed material, as well as preparations in ultra-small amounts 'yemah

These preparations are obtained using a known method, by mixing active substances or combinations of active substances with standard auxiliary substances, for example, standard fillers and solvents, or thinners, dyes, wetting agents, dispersing agents, emulsifiers, antifoaming agents, preservatives, secondary substances that increase stickiness, adhesives, gibberellins, as well as water.

Suitable dyes that may be present in the seed dressings used in accordance with the present invention are all dyes conventionally used for such purposes. At the same time, both slightly water-soluble pigments and water-soluble dyes can be used. Examples include dyes known as rhodamine B, S.I. pigment red 112 and SI, solvent red 1.

Suitable wetting agents that may be included in the seed dressings 60 used in accordance with the present invention are all wetting agents commonly used in agrochemically active ingredient formulations. The use of alkyl naphthalene sulfonates such as diisopropyl or diisobutyl naphthalene sulfonates is preferred.

Suitable dispersing agents and/or emulsifiers that can be contained in seed dressings used in accordance with the present invention are all nonionic, anionic or cationic dispersing agents commonly used for agrochemical active substance preparations. Nonionic or anionic dispersing agents or mixtures of nonionic or anionic dispersing agents are preferably used. Suitable nonionic dispersing agents include, in particular, ethylene oxide/propylene oxide block polymers, alkyl phenol polyglycol ethers and tristyryl phenol polyglycol ether and its phosphated or sulfated derivatives. Suitable anionic dispersing agents include, in particular, lignin sulfonates, polyacrylic acid salts, and aryl sulfonate/formaldehyde condensates.

Antifoaming agents that can be contained in preparations for poisoning seed material used according to the present invention are all substances that prevent the formation of foam, which are usually used for preparations of agrochemical active substances. Silicone antifoam agents and magnesium stearate are mainly used.

Preservatives that can be contained in preparations for poisoning seed material used according to the present invention are all substances used for such purposes in agrochemical compositions. Examples include dichlorphen and benzyl alcohol hemiformal.

Secondary thickening agents, which can be contained in preparations for poisoning seed material used according to the present invention, are all substances used for such purposes in agrochemical compositions. Preferred examples include cellulose derivatives, acrylic acid derivatives, xanthan, modified clays and highly dispersed silica.

The adhesive agents that can be contained in the preparations for impregnation of seed material used according to the present invention are all binders that are usually used in preparations for impregnation of seed material. Preferred examples include polyvinylpyrrolidone, polyvinyl acetate, polyvinyl alcohol and tylos.

Gibberillins, which can be contained in preparations for poisoning seed material used according to the present invention, can preferably be gibberillins At7, AZ (- gibberillic acid), A4 and A7, in particular, preference is given to the use of gibberillic acid. Gibberillins are well-known compounds (see K. UUedieg "Spetiye deg RPapgepzsptsi7- apa zepaadiipdzbekatriipudztine!" |(Spetivigu oi (pe Stor Rgoiesyop Sotrozyopz5 apa Rezviysidevi, my. 2, Zriipdeg Mepad, 1970, p. 401-412).

Suitable seed dressings of the present invention can be used to treat a variety of seed either directly or after dilution with water. For example, concentrates or preparations obtained by diluting them with water can be used to poison the seed material of grain crops such as wheat, barley, rye, oats and triticale, as well as the seed material of corn, rice, canola, peas, beans, cotton, sunflower and beet. , or also seed material of various types of vegetable crops.

Preparations for poisoning the seed material, or preparations obtained by diluting them, used according to the present invention, can also be used for poisoning the seed material of transgenic plants. At the same time, as a result of interaction with substances formed as a result of expression, synergistic effects may also be manifested additionally.

For the treatment of seed material with preparations for seed poisoning, used according to the present invention, or preparations obtained from them by dilution with water, suitable for use are all apparatus for mixing, usually used in seed poisoning. In particular, when poisoning seeds, they act in such a way that the seed material is fed to the mixer, then the necessary amount of drugs that poison the seed material is added in each case, either by itself, or its solution obtained by preliminary dilution with water, and mixed until it is evenly distributed throughout the seed material. If necessary, then drying is carried out.

Consumable amounts of preparations for poisoning seeds according to this invention can vary in a fairly wide range. They depend on the content of each of the active substances in the preparations, as well as on the seed material. Consumption amounts of the combination of active substances 60 are, as a rule, in the range from 0.001 to 50 g per kilogram of seed material, more preferably from 0.01 to 15 g per kilogram.

In addition, the compounds of formula (I) according to the present invention have a very good antimycotic effect. They show a very broad antimycotic spectrum of action, in particular, against dermatophytes and germ fungi, molds and diphasic fungi (for example, against species of the Sapaida genus), such as

Sapadiida airisap5, Sapaida diabgaga), as well as Eridepporpuiop Possozit, species of the genus Azregoiiv5, such as Azregoii5 pideg and Azregoii5 Titidaishv5, species of the genus Tgisporpuip, such as Tgisporpuip tepiadhorpuies5, species of the genus Misgozrogop, such as Misgozrogop sapiz and acidocypii. The list of these fungi in no way means a limitation of the covered mycotic spectrum, but is simply illustrative in nature.

Active substances of formula (I) according to the invention can thus be used both for medicinal and non-medicinal use.

Active substances can be used by themselves, in the form of their preparations or ready-to-use forms prepared from them, such as ready-to-use solutions, suspensions, powders for spraying, soluble powders, means for spraying and granules.

The application is carried out in the usual way, for example, by watering, sprinkling, spraying, scattering, spraying, foaming, spreading, etc. In addition, it is also possible to apply active substances by the method of ultra-small volumes or by injecting into the soil the preparation of the active substance or the active substance itself . You can also process seed material of plants.

In the case of using the active substances according to the invention as fungicides, the consumption amounts can be varied in a relatively wide range, depending on the method of application.

Consumption amounts of active substances are, according to this invention: - when processing plant parts, for example, leaves: from 0.1 to 10,000 g/ha, preferably from 10 to 1,000 g/ha, more preferably from 50 to 300 g/ha ( when applied by watering or spraying, it is even possible to reduce the consumption amount, especially when inert substrates such as mineral wool or perlite are used); - when processing seed material: from 2 to 200 g per 100 kg of seed material, preferably from 3 to 150 g per 100 kg of seed material, more preferably from 2.5 to 25 g per 100 kg of seed material, most preferably from 2.5 up to 12.5 g per 100 kg of seed

From the material; - during soil treatment: from 0.1 to 10,000 g/ha, preferably from 1 to 5,000 g/ha.

The indicated consumable quantities should be considered as an example, but they are in no way limiting the scope of this invention.

Active substances, according to the invention, are used in the veterinary sector and in animal husbandry in a known manner by enteral administration in the form of, for example, tablets, capsules, mixtures, large-dose medicinal products for infusion, granules, pastes, boluses, in the form for feeding with feed, in the form of suppositories, by parenteral administration, such as, for example, by injection (intramuscular, subcutaneous, intravenous, intraperitoneal, etc.), implants, by nasal administration, by dermal application in the form of, for example, dipping or bathing, spraying, drenching and applying to the skin, washing and sprinkling, and by molded articles containing the active substance such as collars, ear tags, tail tags, limb bandages, collars, marking devices etc.

When used to treat livestock, poultry, domestic animals, etc., active substances of formula (I) can be used in the form of preparations (for example, powders, emulsions, liquids) containing active substances in amounts from 1 to 80 wt. 95, or directly, or after dilution 100-10000 times or in the form of a chemical bath.

Ready-to-use compositions may also optionally contain other insecticides, as well as optionally one or more fungicides.

Possible additional mixing components include the insecticides and fungicides mentioned above.

In addition, the compounds according to the invention can be used to protect objects from fouling, especially such as ship hulls, filters, fishing nets, building structures, moorings and signaling systems that come into contact with seawater or sewage.

In addition, the compounds according to the invention alone or in combination with other active substances can be used as antifouling compositions.

The processing method according to the invention can be used to process genetically modified organisms (GMOs), for example, plants or seed material. Genetically modified plants (or transgenic plants) are plants in which a heterologous bo gene is stably integrated into the genome. The term "heterologous gene" essentially means a gene that is obtained or spliced from outside the plant and which, when introduced into the nuclear, chloroplast or mitochondrial genome, provides a transformed plant with new or improved agronomic or other properties through the expression of the protein or polypeptide of interest , or through down-regulating or non-functioning gene(s) present in the plant (using, for example, antisense technology, co-suppression technology or RNAi (|RNA interference) technology). A heterologous gene inserted into a genome is also called a transgene. A transgene, which is determined by its special position in the plant genome, is called a transformational or transgenic event.

Depending on the types of plants or varieties of plants, their location and growing conditions (soils, climate, growing season, fertilizing), processing according to the invention can also lead to additional ("synergistic") effects. For example, the following effects are possible that exceed the effects that should actually have been expected: reduced consumption amounts, broadening the spectrum of activity and/or increasing the activity of active substances and compositions that can be used according to the present invention, better plant growth, increased resistance to high and low temperatures, increased resistance to drought or water or salt content in the soil, increased flowering productivity, easier harvesting, accelerated ripening, higher yields, larger fruits, taller plant, greener leaf color, more early flowering, higher quality and/or higher nutritional value of harvested products, higher sugar concentration in fruits, better stability during storage and/or processing of harvested products.

In certain consumable amounts, the combinations of active substances according to the present invention may also have a potentiating effect in plants. Thus, they are also suitable for mobilizing the plant's defense system against infection by unwanted phytopathogenic fungi and/or microorganisms and/or viruses. This may, if appropriate, be one of the reasons for the increased activity of the combinations according to the present invention, for example, against fungi. Substances that strengthen plants (that cause resistance), in this context, should also be understood as those substances or combinations of substances that are able to stimulate the defense system of plants in such a way that upon subsequent infection with unwanted phytopathogenic fungi and/or microorganisms, and/or viruses , processed plants

Zo demonstrate a significant degree of resistance to these undesirable phytopathogenic fungi, and/or microorganisms, and/or viruses. In this case, undesirable phytopathogenic fungi and/or microorganisms and/or viruses should be understood as phytopathogenic fungi, bacteria and viruses.

Thus, substances according to the invention can be used to protect plants against attack by the above-mentioned pathogens within a defined period of time after treatment.

The period of time, within which the protection is usually effective, extends from 1 to 10 days, preferably from 1 to 7 days after treatment of plants with active substances.

Plants and plant varieties that should preferably be processed according to the present invention include all plants that have genetic material that gives these plants particularly advantageous, useful properties (obtained by breeding and/or biotechnological methods).

Plants and plant varieties, which should also preferably be treated according to the present invention, are resistant to one or more biotic stress factors, i.e., said plants show better protection against animal pests and microbial pests, such as nematodes, insects, mites, phytopathogenic fungi, bacteria, viruses and/or viroids.

Plants and plant varieties that can also be processed according to the present invention are plants that are resistant to one or more biotic stress factors. Abiotic stress conditions may include, for example, drought, exposure to cold and high temperatures, osmotic stress, flooding, increased soil salinity, exposure to increased mineralization, exposure to ozone, high light exposure, limited availability of nitrogen nutrients, limited availability of phosphorus nutrients, or lack of shading .

BO Plants and plant varieties that can also be processed according to the present invention are plants that differ in enhanced yield characteristics. The increased yield of these plants may result from, for example, improved plant physiology, growth and development, namely water use efficiency, water retention efficiency, improved nitrogen utilization, enhanced carbon assimilation, enhanced photosynthesis, increased germination efficiency and accelerated maturation. In addition, yield can be affected by improved plant architecture (under stressed and non-stressed conditions), including early flowering, flowering control for hybrid seed production, shoot vigor, plant size, internode number and length, root growth, seed size, fruit size , pod size, number of pods and ears, number of seeds per pod or ear, seed weight, because increased seed pouring, reduced seed dispersal, reduced pod cracking and lodging resistance. In addition, yield characteristics include seed composition, namely carbohydrate content, protein content, fat content and composition, nutritional value, reduced non-nutritive compounds, improved processability and better storage stability.

Plants that can be treated according to the present invention are hybrid plants that already show signs of heterosis or hybrid vigor, which usually leads to higher yield, vitality, health and resistance to biotic and abiotic stress factors. Such plants are usually obtained by crossing an inbred sterile male parent line (female parent) with another inbred fertile male parent line (male parent). Hybrid seed is usually harvested as a crop from male sterile plants and sold to growers. Male sterile plants can sometimes (e.g., in maize) be produced by defloration (ie, mechanical removal of male reproductive organs or male flowers), but more typically male sterility is the result of genetic determinants in the plant genome. In this case, and especially when the seed is the target product intended to be harvested as a crop from the hybrid plants, it is usually suitable to ensure that the male fertility in the hybrid plants is fully restored. This can be accomplished by ensuring that the males have the appropriate fertility restorer genes that are capable of restoring male fertility in hybrid plants that contain the genetic determinants responsible for male sterility. Genetic determinants for male sterility may be located in the cytoplasm. Examples of cytoplasmic male sterility (CM5) have been described, for example, for Vgazzis species. However, genetic determinants for male sterility may also reside in the nuclear genome. Plants with male sterility can also be produced by methods of plant biotechnology, such as genetic engineering. Particularly useful methods of producing plants with male sterility are described in document UMO 89/10396, in which, for example, a ribonuclease such as barnase is selectively expressed in the cells of the tapetum in the stamens. Fertility can then be restored by expression in tapetum cells of a ribonuclease inhibitor such as barstar.

Plants or plant varieties (obtained by plant biotechnology) that can also be treated according to the present invention are herbicide tolerant plants, i.e.

With plants that have been made tolerant to one or more herbicides. Such plants can be obtained either by genetic transformation or by selection of plants containing mutations that give them such tolerance to herbicides.

Herbicide-tolerant plants, for example, are glyphosate-tolerant plants, that is, plants made tolerant to the herbicide glyphosate or its salts. For example, glyphosate-tolerant plants can be obtained by transforming a plant using a gene encoding the enzyme 5-enolpyruvylshikimate-3-phosphate synthase (ERBRB). Examples of such

The EPZRZ genes are represented by the AgoA gene (mutant ST7) of the bacterium ZaiItopeiia yurpitigist, the SPA gene of the bacterium Adhorasiegichsht 5r., genes encoding ERBR5 of petunia, ERZRZ of tomatoes or EP5P5 of eleusine. It can also be a mutated ERBR5. Glyphosate-tolerant plants can also be obtained by expressing a gene that encodes an oxidoreductase enzyme for glyphosate.

Glyphosate-tolerant plants can also be obtained by expressing a gene that encodes an acetyltransferase enzyme for glyphosate. Glyphosate-tolerant plants can also be obtained by breeding plants containing mutations of the above-mentioned genes that occur in nature.

Other herbicide-resistant plants are, for example, plants that have been made tolerant to glutamine synthase-inhibiting herbicides such as bialaphos, phosphinothricin or glufosinate. Such plants can be obtained by expressing an enzyme, a detoxifying herbicide, or a mutant glutamine synthase enzyme that is resistant to inhibition. One such effective detoxifying enzyme, for example, is the enzyme encoding phosphinothricin acetyltransferase (such as the Bag protein or Zygeriotus spp.).

Plants expressing exogenous phosphinothricin acetyltransferase have been described.

The following herbicide-tolerant plants are plants that have been made tolerant to herbicides that inhibit the enzyme hydroxyphenylpyruvate dioxygenase (HPDO).

Hydroxyphenylpyruvate dioxygenases are enzymes that catalyze the reaction in which parahydroxyphenylpyruvate (HPP) is converted to homogentisate. Plants tolerant to

HPPO-inhibitors can be converted using a gene encoding a naturally occurring stable HPPO enzyme or a gene encoding a mutated HPPO enzyme.

Tolerance to HPRO-inhibitors can also be obtained by transforming plants with genes encoding some enzymes capable of homogenization, contrary to the inhibition of the native HPRO enzyme by the HPRO-inhibitor. The tolerance of plants to HPPO inhibitors can also be improved by transforming plants with a gene encoding the enzyme prephenate dehydrogenase in addition to the gene encoding the HPPO-tolerant enzyme.

The following herbicide-resistant plants are plants that have been made tolerant to acetolactate synthase (AI5) inhibitors. Known AI 5-inhibitors include, for example, herbicides from the classes of sulfonylurea, imidazolinone, triazolopyrimidines, pyrimidinyloxy(thio)benzoates and/or sulfonylaminocarbonyltriazolinone. Various mutations in the AI5 enzyme (also known as acetoxyhydroxyacid synthase, ANA5) are known to confer tolerance to various herbicides and groups of herbicides. The creation of plants tolerant to sulfonylureas and plants tolerant to imidazolinones is described in international publication MO 1996/033270. In addition, plants tolerant to sulfonylureas and imidazolinones are also described, for example, in document UMO 2007/024782.

Other plants tolerant to imidazolinone and sulfonylurea can be obtained by induced mutagenesis, selection in cell cultures in the presence of the herbicide, or mutational selection.

Plants or plant varieties (obtained by methods of plant biotechnology such as genetic engineering) that can also be treated according to the present invention are transgenic insect-resistant plants, i.e., plants made resistant to attack by certain target insects. Such plants can be obtained by genetic transformation or selection of plants containing a mutation that gives them such resistance to insects.

The term "insect-resistant transgenic plants" in this context includes any plant containing at least one transgene containing the coding sequence for encoding: 1) an insecticidal crystal protein from Vasiy5 (pPygpidebi) or parts thereof, namely insecticidal crystal proteins proteins listed online: pEru/Lymly Pevzsi.vizzeh.as.ik/Note/Mei!StisKktoge/V//, or its insecticidal parts, for example, Stu proteins of protein classes StutAbB, StutAs, Stui1E, Stgu2AB, StuZAa or StuzZVb or their insecticidal parts; or 2) a crystal protein from Vasiyna5 "pygipdiepbis or its part, which is insecticidal in the presence of a second other crystal protein from Vasiyya5 (igpdiep5i5 or its part, such as a binary toxin composed of Stgu34 and Stu35 crystal proteins; or

From 3) a hybrid insecticidal protein including parts of various insecticidal crystal proteins from Wasiya5 IpPyhipdiepvi5, such as a hybrid of proteins from 1) above or a hybrid of proteins from 2) above, for example StuTtA.105 protein obtained through the transgenic event MOMOU98034 of maize (MO 2007/ 027777); or 4) a protein from any one of 1) to 3) above, where some, especially from 1 to 10, amino acids are replaced by another amino acid to obtain higher insecticidal activity against target insect species, and/or to broaden the spectrum target insect species exposed to action, either through changes introduced into the coding DNA during cloning or transformation, such as SguzB! protein in transgenic events MOM863 or

Mop88017 of maize, or SguzA protein in the transgenic event MIKb6O4 of maize; or 5) an insecticidal secreted protein from Vasiyya5 (pygipdiepbie or Vasiyyy5 segeiv5, or their insecticidal part, namely vegetative insecticidal (MIR) proteins, specified at: pEr://mmly evsi.iv5zeh.as.ik/pote/MeiYi Stisktoge/Vumir .piti, for example, proteins from the MIRZAa class of proteins; or b) a secreted protein from Wasiya5 IpPyhipdiepvi5 or Wasiya5 segei5 that is insecticidal in the presence of a second secreted protein from Wasiya5 (pygypdieppoie or B. segei5, such as a binary toxin composed of MYRTA and MIRA proteins (M/O 1994/21795); 7) hybrid insecticidal protein containing parts of various secreted proteins from

Vasiy5 "(Pyhipdiepzi5 or Vasiyts5 segets5, such as a hybrid of proteins in 1) above or a hybrid of proteins in 2) above; or

BO 8) a protein from any one of 1) to 3) above, where some, especially from 1 to 10, amino acids are replaced by another amino acid to obtain higher insecticidal activity against target insect species, and/or to expand the range of target species of insects exposed and/or due to changes introduced into the DNA coding during cloning or transformation (even during the coding of the insecticidal protein), such as the MIRZZZAa protein in the cotton SOT102 transgenic event.

Of course, insect-resistant transgenic plants, in this context, also includes any plant containing a combination of genes encoding proteins from any one of the above classes 1 to 8. In one embodiment, the insect-resistant plant comprises more than one transgene encoding a protein of any one of the above classes 1 to 8, in order to widen the range of target insect species to be acted upon when using a variety of proteins,

targeting different target insect species, or to slow the development of insect resistance in plants by using different proteins that are insecticidal to the same target insect species but have different mechanisms of action, such as binding to different receptor binding sites in the insect .

Plants or plant varieties (obtained by methods of plant biotechnology, such as genetic engineering), which can also be processed according to the present invention, are tolerant to abiotic stress factors. Such plants can be obtained by genetic transformation or selection of plants containing a mutation that provides such tolerance to stress. Particularly useful plants with tolerance to stress include the following: a) plants that contain a transgene capable of reducing the expression and/or activity of the gene encoding poly(AYUR-ribose) polymerase (PAER) in plant cells or plants; p) plants that contain a transgene that enhances stress tolerance, capable of reducing the expression and/or activity of RAKS coding genes of plants or plant cells; c) plants that contain a transgene that enhances stress tolerance, encoding a plant functional enzyme from the synthetic pathway of nicotinamide adenine dinucleotide reutilization, including nicotinamidase, nicotinate phosphoribosyltransferase, nicotinic acid mononucleotide adenyltransferase, nicotinamide adenine dinucleotide synthetase, or nicotinamide phosphoribosyltransferase.

Plants or plant varieties (obtained by methods of plant biotechnology such as genetic engineering) that may also be processed according to the present invention exhibit altered quantity, quality and/or storage stability of the crop product, and/or a change in the properties of specified ingredients of the crop product, namely: 1) transgenic plants that synthesize modified starch, which according to its physicochemical properties, in particular, according to the amylose content or the amylose/amylopectin ratio, the degree of branching, the average chain length, the distribution of side chains, the behavior associated with 'viscosity, gelatinizing power, starch grain size and/or starch grain morphology, altered compared to starch synthesized in plant cells or wild-type plants, such that this modified starch is better suited for a specific application.

2) Transgenic plants that synthesize non-starch hydrocarbon polymers or that synthesize non-starch hydrocarbon polymers with altered properties compared to wild-type plants without genetic modification. Examples are plants that produce polyfructose, especially the inulin and levan types, plants that produce alpha-1,4-glucans, plants that produce alpha-1,6-branched alpha-1,4-glucans, and plants that produce alternan . 3) Transgenic plants that produce hyaluronan.

Plants or plant varieties (which may be produced by plant biotechnology methods such as genetic engineering) which may also be processed according to the present invention are plants such as cotton plants with altered fiber properties. Such plants, which can be obtained by genetic transformation or selection of plants containing a mutation that confers such altered fiber properties, and include: a) plants, such as cotton plants, containing an altered form of cellulose synthase genes; p) plants, such as cotton plants, containing a modified form of g5m/2 and hem/3 homologous nucleic acids; c) plants, such as cotton plants, with increased expression of sucrose phosphate synthase; a) plants, such as cotton plants, with increased expression of sucrose synthase; e) plants, such as cotton plants, in which the time regime of the plasmodesmal reverse mechanism per fiber cell is changed, for example, due to the downregulation of fiber-selective ID-1,3-glucanase;

TT) plants, such as cotton plants, having fibers with altered reactivity, for example through expression of the M-acetylglucosaminotransferase gene, including pods and chitin synthase genes.

Plants and plant varieties (obtained by plant biotechnology methods such as genetic engineering) that can also be processed according to the present invention are plants such as oilseed rape and related Vgazzis plants with altered oil profile characteristics. Such plants, which can be obtained by genetic transformation or selection of plants, containing a mutation that confers such changed oil properties and include: a) plants, such as oilseed rape plants, producing oil with a high content of oleic acid;

B) plants, such as oilseed rape plants, producing oil with a low content of 60 linolenic acid;

c) plants, such as rapeseed plants, that produce oil with a low content of saturated fatty acids.

Particularly useful transgenic plants that can be treated according to the present invention are plants that contain one or more genes that encode one or more toxins and transgenic plants that are sold under the trade names:

SANWOF (e.g. maize, cotton, soybeans), KposkOcie (e.g. maize),

ViesSagtF (e.g. maize), VT-HigaFb (e.g. maize), 5apiykF (e.g. maize), VoiYidagaeF (cotton), MysoipF (cotton), Mysoip Z33VF (cotton), MaishgesSagaF (e.g. maize), RgoiesiaF and Mem/ and eai" (potatoes). Examples of herbicide-tolerant plants that may be listed are corn, cotton, and soybean varieties that are commercially available under the trade names: Koipdir KeadufF (glyphosate tolerant, e.g., corn, cotton, soybeans), and irbepu GipkF (tolerance to phosphinothricin, e.g. oilseed rape), IMIF (tolerance to imidazolinone) and 5C5F (tolerance to sulfonylurea), e.g. maize. Herbicide-resistant plants (plants bred conventionally for tolerance to herbicides) that may be specified include varieties sold under the name SiegeliaF (eg, corn).

Particularly useful transgenic plants that can be treated in accordance with the present invention are plants containing transforming events, or a combination of transforming events, that are listed, for example, in databases from various national or regional regulatory agencies (see, e.g., peEr://dptoipto.)go.y/dtr Bgozh/ze.azrh and pPEer:/Llymly.adrioz.sot/abaze.rpr).

Said plants can be treated according to the present invention in a particularly advantageous way with compounds of the general formula (I) and/or mixtures of active substances according to the present invention. The preferred ranges established above for active substances or mixtures are also valid for the treatment of these plants. Particular preference is given to the treatment of plants with compounds or mixtures specifically indicated in this text.

Active substances or compositions according to the invention can be used to protect plants against attack by the above-mentioned pathogens within a defined period of time after treatment. The time period during which the protection is usually effective extends, as a rule, from 1

Ko) up to 28 days, preferably from 1 to 14 days, more preferably from 1 to 10 days, most preferably from 1 to 7 days after treatment of plants with active substances, or within up to 200 days after treatment of seeds.

The preparation and use of the active substances according to the present invention of the formula (Her) are illustrated by the examples below. However, the invention is not limited to these examples.

General Notes: Unless otherwise noted, all chromatographic purification and separation steps are performed on silica gel and using a solvent mixture gradient from 0:100 ethyl acetate/cyclohexane to 100:0 ethyl acetate/cyclohexane.

Preparation of compounds of formula (1-1)

Stage 1 tert-Butyl 4-(4-(5-(2-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-yl)piperidin-1- carboxylate

To a solution of tert-butyl 4-A4-(hydroxyimino)methyl/|-1,3-thiazol-2-yl)upiperidine-1-carboxylate (3.46 g) and 2-vinylphenol (1.60 g) in ethyl acetate ( 50 ml) was added, at room temperature, potassium bicarbonate (5.55 g) and M-chlorosuccinimide (1.78 g), followed by one drop of water. After stirring at 60 "C overnight, ethyl acetate and water were added to the reaction mixture, which was extracted with ethyl acetate. The organic extracts were dried over sodium sulfate and concentrated under reduced pressure. The residue was purified by chromatography.

Tert-butyl /4-14-(5-(2-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-yl)upiperidine-1-carboxylate was obtained (1.70 g)

Stage 2

4-14-(5-(2-Hydroxyphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-ylpiperidinium chloride

To the solution tert-butyl 4-(4-(5-(2-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-yl)upiperidin-1- carboxylate (1.70 g) in dichloromethane was added dropwise at 0 "C to a 4 molar solution of hydrogen chloride (4.0 equiv.) in 1,4-dioxane. The reaction mixture was stirred at 0 "C and then gradually warmed to room temperature After stirring overnight, the solvent and excess hydrogen chloride were removed to give 4-(4-(5-(2-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3- thiazol-2-yl)piperidinium (1.45 g).

Stage Z

2-3,5-Bisidifluoromethyl)-1H-pyrazol-1-yl|-1-(4-(4-(5-(2-hydroxyphenyl)-4,5-dihydro-1,2-oxazole-

C-yl|-1,3-thiazol-2-yl)piperidin-1-yl)ethanone

Oxalyl chloride (1.50 g) and one drop of M,M- dimethylformamide.

The reaction mixture was stirred at room temperature for 60 minutes. The solvent and excess reagent were removed under reduced pressure. The remainder of the solid substance was again dissolved in dichloromethane and added dropwise at 0 "С to a solution of 4-14-|5-(2-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-z-yl|-1,3 -thiazol-2-ylpiperidinium (1.45 g) and triethylamine (5.5 mL) in dichloromethane (14 mL). The reaction mixture was stirred at room temperature for 3 hours. Then a concentrated sodium bicarbonate solution was added to the mixture, and the aqueous phase was removed , and extracted with ethyl acetate. The combined organic phases were dried over sodium sulfate and concentrated. Purification by column chromatography gave 2-3,5-bisidifluoromethyl)-1H-pyrazol-1-yl|-1-(4-4-I( 5-(2-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-yl)piperidin-1-yl)ethanone (900 mg).

Stage 4 2-13,5-Bis(difluoromethyl)-1H-pyrazol-1-yl|-1-(4-14-(5-(2-C3-(trimethylsilyl)prop-2-yn-1-yl) oxy)phenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-yl)piperidin-1-yl)ethanone (1-1)

To a solution of 2-3,5-bisidifluoromethyl)-1H-pyrazol-1-yl|-1-(4-14-(5-(2-hydroxyphenyl)-4,5-dihydro-1,2-oxazole-3 -yl|-1,3-thiazol-2-ylpiperidine-1-iluethanone (150 mg) and potassium carbonate (43 mg) in

Potassium iodide (19 mg) and (3-bromoprop-1-yn-1-ylUtrimethyl)silane (64 mg) were added to DMF (8 mL) at room temperature. The reaction mixture was stirred at 80 "C for 9 hours. Dilute hydrochloric acid was then added to the mixture, which was extracted with ethyl acetate. The combined organic phases were dried over sodium sulfate and concentrated. Purification by column chromatography gave 2-3,5-bisidifluoromethyl)- 1 H-pyrazol-1-yl|-1-(4-14-(5-(2-13- (trimethylsilyl)prop-2-yn-1-yl|Ioxyphenyl)-4,5-dihydro-1,2 -oxazol-3-yl|-1,3-thiazol-2-ylpiperidin-1-yl)ethanone (8 mg).

Preparation of compounds of formula (1-2)

Stage 1 2-3,5-Bis(difluoromethyl)-1H-pyrazol-1-yl(|-1-(4-14-(5-(2-C3-(1-naphthyl)prop-2-yn-1 -

Zoyl|oxy)phenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-yl)piperidin-1-yl)ethanone (1-2)

To a solution of 2-3,5-bisidifluoromethyl)-1H-pyrazol-1-yl|-1-(4-14-(5-(2-hydroxyphenyl)-4,5-dihydro-1,2-oxazole-3 -yl|-1,3-thiazol-2-ylpiperidine-1-iluethanone (150 mg) and potassium carbonate (43 mg) in

DMF (8 ml) was added, at room temperature, potassium iodide (19 mg) and 2-(3-bromoprop-1-yn-1-ylnaphthalene (82 mg). The reaction mixture was stirred at 80 "C for 9 hours. Then to diluted hydrochloric acid was added to the mixture, which was extracted with ethyl acetate. The combined organic phases were dried over sodium sulfate and concentrated. Purification by column chromatography gave 2-3,5-bisidifluoromethyl)-1H-pyrazol-1-yl|-1-( 4-14-(5-(2-13-(1-naphthyl)prop-2-yn-1-yl|oxyphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3 -thiazol-2-yl)piperidin-1-yl)uethanone (25 mg).

Preparation of compounds of formula (1-17)

Stage 1 2-(1-13,5-Bis(difluoromethyl)-1H-pyrazol-1-yl|iacetyl)piperidin-4-yl)-1,3-thiazole-4-carbaldehyde

Oxalyl chloride (6.40 g) was added to a solution of (|3,5-bis(idifluoromethyl)-1H-pyrazol-1-yl|acetic acid (4.18 g) in dichloromethane (28 ml) at 0 "С and one drop of M,M-dimethylformamide.

The reaction mixture was stirred at room temperature for 60 minutes. The solvent and excess reagent were removed under reduced pressure. The remaining solid was redissolved in dichloromethane and added dropwise at 0 "C to a solution of 4-(4-formyl-1,3-thiazol-2-yl)piperidinium chloride (3.91 g) and triethylamine (9.9 ml) in dichloromethane (14 mL). The reaction mixture was stirred at room temperature overnight. Then water was added to the mixture and the aqueous phase was removed and extracted with ethyl acetate. The combined organic phases were dried over sodium sulfate and concentrated. Purification by column chromatography gave 2-( 1-13,5-Bisidifluoromethyl)-1H-pyrazol-1-yl|Iacetyl)piperidin-4-yl)-1,3-thiazole-4-carbaldehyde (2.00 g).

Stage 2

2-(1-13,5-Bisidifluoromethyl)-1H-pyrazol-1-ylacetyl)piperidin-4-yl)-1,3-thiazol-4-carbaldehyde oxime

To a solution of 2-(1-(13,5-bisidifluoromethyl)-1H-pyrazol-1-yl|1acetyl)piperidin-4-yl)-1,3-thiazol-4-carbaldehyde (2.00 g) in ethanol (33 mL) was added dropwise with hydroxylamine (50 95 in water, 0.36 mL) at room temperature. The reaction mixture was stirred at room temperature for about 24 hours, then the solvent was removed under reduced pressure. Oxime 2-(1-13,5-

bis(difluoromethyl)-1H-pyrazol-1-yl|acetyl)piperidin-4-yl)-1,3-thiazole-4-carbaldehyde (2.00 g).

Stage C tert-Butyl (4-(3-(2-(1-1H3,5-bisidifluoromethyl)-1H-pyrazol-1-yl|acetyl)piperidin-4-yl)-1,3- thiazol-4- yl|-4,5-dihydro-1,2-oxazole-5-iluphenyl)carbamate (1-17)

To a solution of 2-(1-13,5-bis(difluoromethyl)-1H-pyrazol-1-yl|Iacetyl)piperidin-4-yl)-1,3-thiazole-4-carbaldehyde oxime (1.50 g) and tert-butyl (4-vinylphenyl)carbamate (0.94 g) in ethyl acetate (140 mL) was added, at room temperature, potassium bicarbonate (1.79 g) and M-chlorosuccinimide (0.50 g), and then one drop water After stirring the reaction mixture at 60 "C for 3 hours, ethyl acetate and water were added, and the mixture was extracted with ethyl acetate. The organic extracts were dried over sodium sulfate and concentrated under reduced pressure. The residue was purified by chromatography. Tert-butyl (4-(3- (2-(1-H3,5-bisidifluoromethyl)-1H-pyrazol-1-yl|Iacetyl)piperidin-4-yl)-1,3-thiazol-4-yl|-4,5-dihydro-1, 2-oxazole-5-iluphenyl)ucarbamate (0.90 g).

Preparation of compounds of formula (1-40)

Stage 1 tert-Butyl 4-34-(15-(2-acetylphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-yl)piperidine-1-carboxylate (KhMII-1)

To a solution of tert-butyl 4--4-KA/E)-(hydroxyimino)methyl|-1,3-thiazol-2-ylpiperidine-1-carboxylate (4.5 g) and 1-(2-vinylphenyl)ethanone ( 2.32 g) in ethyl acetate (70 ml) was added, at room temperature, potassium bicarbonate (7.23 g) and M-chlorosuccinimide (2.31 g), followed by three drops of water. The reaction mixture was stirred at 60 "C for 3 hours, then ethyl acetate and water, and the mixture was extracted with ethyl acetate. The organic extracts were dried over sodium sulfate and concentrated under reduced pressure. The residue was purified by chromatography.

Tert-butyl 4-(4-(5-(2-acetylphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-yl)upiperidine-1-carboxylate was obtained (4.64 g).

Stage 2

Hydrochloride 1-(2-13-(2-(piperidin-4-yl)-1,3-thiazol-4-yl|-4,5-dihydro-1,2-oxazol-b-iluphenyl)ethanone (ChPI- 1)

To a solution of tert-butyl 4-4-(5-(2-acetylphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-yl)ipiperidin-1-carboxylate (500 mg) in 1,4-dioxane (5 ml) was added dropwise at 0 "s to a 4 molar solution of hydrogen chloride in 1,4-dioxane (4.2 ml). The reaction mixture was stirred at

From 0 C, and then gradually heated to room temperature. After stirring overnight, the solvent and excess hydrogen chloride were removed. 1-(2-(3-(2-(piperidin-4-yl)-1,3-thiazol-4-yl|-4,5-dihydro-1,2-oxazol-5-iluphenyl)ethanone hydrochloride was obtained ( 430 mg).

Stage C 1-(4-4-(15-(2-Acetylphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-yl)upiperidin-1-yl )-2-I|5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl|ethanone

Solution A: To a solution of |5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl|acetic acid (0.7 g) in dichloromethane (20 ml) at room temperature was added one drop of M,M-dimethylformamide and , drops, oxalyl chloride (0.8 ml). After stirring at room temperature for 2 hours, the solvent was removed and the residue was redissolved in dichloromethane (10 mL) (Solution A).

To a solution of 1-(2-13-(2-(piperidin-4-yl)-1,3-thiazol-4-yl|-4,5-dihydro-1,2-oxazol-5-iluphenyl)ethanone hydrochloride ( 1.20 g) in dichloromethane (20 mL) was added, at room temperature, to diisopropylethylamine (1.60 mL). After 15 minutes, solution A was added dropwise. After stirring at room temperature overnight, water was added to the reaction mixture, which was extracted The organic extracts were dried over sodium sulfate and concentrated under reduced pressure.The residue was purified by chromatography.

1-(4-(4-(5-(2-acetylphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-yl)piperidin-1-yl) was obtained )-2-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)ethanone (1.04 g).

Stage 4 1-(4-(4-5-(2-(M-Hydroxyethanemidoyl)phenyl|-4,5-dihydro-1,2-oxazol-3-yl)-1,3-thiazol-2-yl) upiperidin-1-yl|-2-(5-methyl-3-trifluoromethyl)-1H-pyrazol-1-yl|ethanone (1-40)

To a solution of 1-(4-14-(5-(2-acetylphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-yl)piperidin-1-yl )-2-(B-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl|stanone (150 mg) in ethanol (5 ml) was added dropwise to hydroxylamine (50 90 in water, 4 equiv.) at room temperature temperature. After stirring at room temperature overnight, water was added to the reaction mixture, which was extracted with ethyl acetate. The organic extracts were dried over sodium sulfate and concentrated under reduced pressure. The residue was purified by chromatography. 1 -I(4-(4-15- (2-(M-Hydroxyethanemidoyl)phenyl|-4,5-dihydro-1,2-oxazol-2-yl)-1,3-thiazol-2-yl)piperidin-1-yl)-2-(5- methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl|ethanone (33 mg).

Preparation of compounds of formula (1-41)

Stage 1 tert-Butyl 4-4-I(I5-(2-formylphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-yl)/piperidin-1 - carboxylate (KHMII-2) tert-Butyl 4-14-K2/E)-(hydroxyimino)methyl/)-1,3-thiazole-2-ylpiperidine-1-carboxylate (5.6 g) and 2-vinylbenzaldehyde ( 2.61 g) were subjected to interaction in the same way as 1-40 (stage 1). Tert-butyl 4-14-(5-(2-formylphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-yl)piperidine-1-carboxylate was obtained ( 5.69 g).

Stage 2

Tert-Butyl 2-13-(2-(piperidin-4-yl)-1,3-thiazol-4-yl|-4,5-dihydro-1,2-oxazol-b-ylbenzaldehyde (ChPI-2) hydrochloride 4-4-I(I5-(2-formylphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-yl)/piperidine-1-carboxylate (5, 1 g) was subjected to interaction in the same way as 1-40 (stage 2). Hydrochloride 2-13- (g-(piperidin-4-yl)-1,3-thiazol-4-yl|-4,5-dihydro-1 was obtained, 2-oxazol-5-yl, ibenzaldehyde (4.35 g).

Stage Z

M-(5-Chloro-2-methylphenyl)-4-14-(5-(2-formylphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2- yl)piperidine-1-carboxamide

To a suspension of 2-13-(2-(piperidin-4-yl)-1,3-thiazol-4-yl|-4,5-dihydro-1,2-oxazol-5-yl)benzaldehyde (1.43 d) in dichloromethane (30 ml) and diisopropylethylamine (0.73 ml) was added, at room temperature, 4-chloro-2-isocyanate-i-methylbenzene (700 mg) and one drop of 1,8-diazabicyclo/5.4.Oundec- 7th (OB). The mixture was stirred at room temperature overnight and then water was added. The aqueous phase was removed and extracted with ethyl acetate. The combined organic phases were dried over sodium sulfate and concentrated under reduced pressure.

The residue was purified by chromatography. M-(5-chloro-2-methylphenyl)-4-14-|5-(2-formylphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2 -yl)ipiperidine-1-carboxamide (1.23 g).

Stage 4

M-(5-Chloro-2-methylphenyl)-4-I4-(5-2-(methoxyimino)methyl|phenyl)-4,5-dihydro-1,2-oxazol-3-yl)-1,3- thiazol-2-yl|piperidine-1-carboxamide (1-41)

M-(5-Chloro-2-methylphenyl)-4-14-(5-(2-formylphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-

Zo ilupiperidine-1-carboxamide (150 mg) and O-methylhydroxylamine hydrochloride (26 mg) were reacted similarly to I-40 (stage 4). M-(5-chloro-2-methylphenyl)-4-(4-(5-12-

Imethoxyimino)methyl|phenyl)-4,5-dihydro-1,2-oxazol-3-yl)-1,3-thiazol-2-yl|piperidine-1-carboxamide (175 mg).

Preparation of compounds of formula (1-26)

Stage 1 2-13-(2-(1-C9,5-Bisidifluoromethyl)-1H-pyrazol-1-yl|Iacetyl)piperidin-4-yl)-1,3-thiazol-4-yl|-4,5 - dihydro-1,2-oxazol-5-yl) benzaldehyde

4-(4-(5-(2-formylphenyl)-4,5-dihydro-1,2-oxazol-3-yl|-1,3-thiazol-2-ylpiperidinium chloride (433 mg) and 3,5- bisibidifluoromethyl)-1H-pyrazol-1-yl|!iidoacetic acid (285 mg) was subjected to a reaction similar to I-40 (stage 3). pyrazol-1-yl)acetyl)piperidin-4-yl)-1,3-thiazol-4-yl|-4,5-dihydro-1,2-oxazol-5-yl)benzaldehyde (330 mg).

Stage 2

O-methyloxime 2-(3-(2-(1-13,5-bisidifluoromethyl)-1H-pyrazol-1-yl|Iacetyl)piperidin-4-yl)-1,3-thiazol-4-yl|- 4,5-dihydro-1,2-oxazol-5-ylbenzaldehyde (1-26) 2-13-(2-(1-C9,5-Bis(difluoromethyl)-1H-pyrazol-1-yl|Iacetyl) piperidin-4-yl)-1,3-thiazol-4-yl|-4,5-dihydro-1,2-oxazol-5-yl/benzaldehyde (150 mg) and O-methylhydroxylamine (24 mg) were reacted similarly 1-40 (stage 4). O-methyloxime /-2-13-(2-(1-(13,5-bis(idifluoromethyl)-1H-pyrazol-1-yl|acetyl)piperidin-4-yl)-1,3-thiazol-4 -yl|-4,5-dihydro-1,2-oxazole-5-ylbenzaldehyde (169 mg).

Examples

In tt iy / In M 2 1

XX m x-e-0-3--8 d-- or o (A) (y

Structural elements C", 0)71-1 and 022-3, given in Table 1, are defined as follows:

In Z du to y y /

M MI - M x BY x 1144. s- ov 0-1 -

For all the compounds listed in Table 1, p-:0 and 12 - a simple bond;

Table 1 p a || x|sevy|o || i | yur 3,5- 2-Ц3-

And bisidifluorom 4 24. (trimethylsilyl) 4, 71 Iai, ethylutn- | Ne snua rn re NOI prop-oin-y- 4,BBBY pyrazol-1-yl yl|Ioxy)phenyl 3,5-

And bisidifluorom 4 24. 2-(IZ-(naphthalene-1- | 4.81CaY,

Me | ethylutn- | Not snua rn re HO duprop-o-in-i- 4,686) pyrazol-1-yl yl|Ioxy)phenyl

B-methyl-3-

Y (trifluorometh 4 24. 3-1 E/2)-M-

From il)-1n- snu un op un methoxyethanimidoi Zla pyrazol-1-yl liphenyl 3,5- ol | bisidiftorm and od. 2-KE/2)- 4 ethyl)-TH- СNe snu un op un (hydroxyimino) 2.1 a) pyrazol-1-yl methylphenyl 3,5-

And bisb (idiftorm and 24. 3-1 E/2)-M-

I5 ethyl)-TH- sne snu op un ethoxyethanimidoyl 3,92Ia) pyrazol-1-yl phenyl 3,5- 3-(E/2)-Kpropane- bis(difluorom and 24. 2- ethyl)-TH- СNe snu un op un yloxy)imino|methy 4.,06ia) pyrazol-1-yl l)phenyl

B-methyl-3-

Y (trifluorometh 4 24. 3-1 E/2)-M-

SHI yl)-1n- sne snu un op un hydroxyetanimido 2.ViaI pyrazol-1-yl Ttl|Ifenyl

B-methyl-3-3-CE/2)-K(propan- (trifluorometh and 24.2-yl)-TtH- snu un oprn yloxy)imino|methy 4,158) pyrazol-1-yl luphenyl

B-methyl-3-3-1 E/2)-M- (trifluorometh 4 24. (propan-2- yl)-1H- СНе snu un OH yloxy)ethanimidoi | 7618) pyrazol-1-yl liphenyl

B-methyl-3-

Y (trifluorometh 4 24. Z3-KE/2)- po il)-t1n- CH» sleep and op |n (hydroxyimino)meth 2.63) pyrazol-1-yl yl|phenyl

B-methyl-3-

Y (trifluorometh and od. Z3-KE/2)- schi yl)-1n- СНе snu un op un (ethoxyimino)methy Z,Ba) pyrazol-1-yl liphenyl nle|v-chloro- |МН|О |snuis |n oz |nH |z) 2062)

Table 1 pa | -7|x|ha vo || i | or methylphenyl (ethoxyimino)methy liphenyl 3-CE/2)-K(propane-2- - 1 24.

Z B-chlor-2- MH snu H cZ H yloxy)imino|methy 4,4a) methylphenyl l)phenyl

Z3-KE/2)-

I-14 | 5-chloro-2- MH sna |n 03 |H (hydroxyimino) 2.79Gai methylphenyl methylphenyl

B-methyl-3- in | (trifluorometh ! m. 3-(E/2)-

Il15 il)-tH- CHneg sni)a Hn 0-3 Hn (methoxyimino) 3,45IaY pyrazol-1-yl methylphenyl 3,5-

And bis(difluoro and od. Z-KE/2)- 76 ethyl)-1H- СNe snu and OZ and (methoxyimino) 3, ZVia) pyrazol-1-yl methylphenyl 3,5-

And bis(difluorom and unit 4-Ctret-Z,45Ia), 17 ethyl)in- | Not sleeping holes of NOI oxycarbonyl | ZB) pyrazol-1-yl amino|phenyl 3,5-

And bisb (idiftorm and 24. 3-1 E/2)-M-

IV ethyl)-TH- snu un op un hydroxyethanimido 2.7 Cha) pyrazol-1-yl Ttl|Ifenyl

Z3-KE/2)-

I-19 | 5-chloro-2-MH sleep! |n 0-3 Hn (methoxyimino) 3.76Ia methylphenyl methylphenyl 3.5- 3-1 E/2)-M-

And bisidifluorom and 24. (propane-2-

I-th ethyl)-1H- СНе sleep and OZ and yloxy)ethanimidoi 4,32ia) pyrazol-1-yl liphenyl 3,5-

And bisb (idiftorm and 24. 3-1 E/2)-M-

I21 ethyl)-TH- snu un op un methoxyethanimidoi 3,5oga) pyrazol-1-yl liphenyl 3,5-

Y bisb (idiftorm 4 24. Z3-KE/2)-

I-22 ethyl)-1H- CHneg sni)a Hn 0-3 Hn (hydroxyimino) 2,57Uai pyrazol-1-yl methylphenyl 3-1 E/2)-M-

I-23 | 5-chloro-2- MH sniaT |n 023 Н methoxyethanimidoi | 3.99G methylphenyl liphenyl 3,5-

And bisb(idifluorom and od. З3-КЕ/2)- 24 ethyl)-ТН-СНе snu un op un (ethoxyimino)methy З, 71a) pyrazol-1-yl liphenyl 3,5-

And bisidiftorm and one. 2,2Ia, ethylutn- | UNe snu rn re NOI A (acetylamino) | 2,24IB) pyrazol-1-yl phenyl 3,5-

And bisidifluorom and 24. 2-KE/2)- 26 ethyl)-TH- СNe snu un op un (methoxyimino) 3,59ia) pyrazol-1-yl methylphenyl

Table 1 pa f|I-7|x|ha vo || i | or 3.5-

And bis(difluoro and od. 2-KE/2)- 27 ethyl)-TH- СNe snu un op un (ethoxyimino)methy 3.91ha) pyrazol-1-yl liphenyl 3.5- 2-1 E/2) -M-

And bisidifluorom and 24. (propan-2-28 ethyl)-1H-Sne snu and Fe-Z and yloxy)ethanimidoi 4,33Ia) pyrazol-1-yl liphenyl

B-methyl-3- zd (trifluorometh! m. 2-CE/2)- 29 yl)-1n- СNe snu un op un (ethoxyimino) methy cha) pyrazol-1-yl liphenyl

B-methyl-3- 2-X E/2)-M-

And (trifluorometh and one (propane-2-

I-30 yl)-TH- CHneg sni)a H 0-3 Hn yloxy)ethanimidoi 4 44a pyrazol-1-yl liphenyl

B-methyl-3-

Y (trifluorometh Y 2-1 E/2)-M-

IZ il)-1n- sne snu un op un methoxyethanimidoi 3, 7za) pyrazol-1-yl liphenyl 3,5-

And bisb (idiftorm and 24. 2-1 E/2)-M-

I-Z2 ethyl)-1H- snu N Oz H methoxyethanimidoi 3,baa) pyrazol-1-yl liphenyl 2-KE/2)-

I-33 | 5-chlor-2- MH sna |n 03 |H (ethoxyimino)methy | 4,25(a) methylphenyl liphenyl

B-methyl-3-

Y (trifluorometh 4 24. 2-KE/2)-

FOR ill. CH» snu un 7 GNOOY (methoxyiminometh| Ua pyrazol-1-yl yl|phenyl 3,5-

Y bisb(idifluorom and 24. 2-1 E/2)-M- ethyl)-TH- snu un op un hydroxyethanimido Zo pyrazol-1-yl Ttl|Ifenyl 2-KE/2)-

I-36 | 5-chlor-2- MH sleep |n 03 |H (hydroxyimino) 3,05(a) methylphenyl methylphenyl 2-(E/2)-Kpropane- 2- - 1 24. 137 B-chloro-2- MH sleep H Oz Nyloxy)imino|methy 4,6La methylphenyl l)phenyl

B-methyl-3-

Y (trifluorometh 4 24. 2-KE/2)-

I-38 yl)-TH- CHneg sni)a H 0-3 Hn (hydroxyimino) 2.85Ia pyrazol-1-yl methylphenyl

B-methyl-3-2-CE/2)-(propane-

І (trifluorometh and od. 2-39 yl)-1H- СNe snu and OZ and yloxy)imino|methy 4,3la pyrazol-1-yl l)phenyl

B-methyl-3-

Y (trifluorometh 4 24. 2-1 E/2)-M-

I-40 yl)-1H- sne snu N Oz H hydroxyetanimido 2,92Ia) pyrazol-1-yl Ttl|Ifenyl tivouronis |snev |n Gozhz |n | diluted vinegar

Table 1 pa I-I x|ha vo || 4 sh i | or methylphenyl (methoxyimino) methylphenyl 3,5- 2-(E/2)-Kpropane-

And bisidifluorom and 24. 2- 42 ethyl)-TH- СNe snu un op un yloxy)imino|methy 4,25ia) pyrazol-1-yl l)phenyl 3,5-

And bisidifluorom 4 24. 2- 3,16(ai, 43 ethylutn- | UNe snuarn rereni omethylsulfonyl 3,09|B) pyrazol-1-yl)oxy|phenyl 3- (difluoromet 2,86(a)

I-44 | yl)-5-methyl-| SNEO dream: H 023 СНз | 2- 2 VI. 1H-pyrazole-Kmethylsulfonyl and 1-yl)oxy|phenyl

B-methyl-3- 2-Sh2-

Y (trifluorometh and mono methoxyethyl)

I45 yl)-tH- CHneg sni)a Hn 0-3 Hn sulfanyl|methyl)u 3.64Ca pyrazol-1-yl phenyl

B-methyl-3-

Y (trifluorometh 4 24. 2-Kprop-2-yn-1-

I-46 yl)-tH-CHneg sni)a Hn 0-3 Hn yloxy)methyli|phen 3,43aY pyrazol-1-yl yl

B-methyl-3-

And (trifluorometh and 24. 2-

I47 yl)-tH- CHneg sni)a Hn 0-3 Hn (acetoxymethyl) 3,Z1Gai pyrazol-1-yl phenyl 3,5- 2--M(4-

And bisidiftorm and one. methylphenyl) 4.31ai, 48 ethylutn- | UNe snua rn re reni sudfoniluxiu | 415IB) pyrazol-1-yl phenyl 3- (difluorometh 2-Scha4-4 oBIa)

I-49 | yl)-5-methyl-| SNe snIiaT |n 0-3 СНз | methylphenyl) General 1H-pyrazole-sulfonyl|oxy) and 1-yl phenyl 3,5-

And bisidifluorom 4 24. 2,6-difluoro-3- 2,95Ia), 150 ethylutn- | UNe snuarn re NOI dmethylsulfonyl 2,88|B) pyrazol-1-yl oxy|Ifenyl 3- (difluorometh

I-51 | yl)-5-methyl-| СНег сниИс ||н 023 H 2-oxy 1H-pyrazole-Kmethylsulfonyl and 1-yl)oxy|phenyl 2,5-2-chloro-6- 3,35(a)

I-52 | dimethylphen | MN sleep! |n 0-3 Hn Imethylsulfonyl Z oBIB yl)oxy|phenyl " 3,5-

And bisidifluorom and 24. 2-Kprop-2-yn-1- 53 ethyl)-TH- СNe snu un op un yloxy) methyl|phen 3,91a) pyrazol-1-yl yl 2-chloro-6- Z,BAa )

I-54 | 5-chloro-2- MH sleep

Table 1 pa f|I-7|x|ha vo || i | or 3.5-

And bisb(idifluorom and 2. ethyl)-TH- СNe snu un op un (acetoxymethyl) Z,2hia) pyrazol-1-yl phenyl 3,5- 2-4Ц2-

And bisidifluorom and 24. methoxyethyl) 56 ethyl)-1H- СNe sleep and Fe-3 and sulfinyl|methyl) 2.5hia) pyrazol-1-yl phenyl 3,5- 2-Ш(2-

And bisidifluorom and 24. methoxyethyl) 57 ethyl)-1H- СНе snu and Fe-Z and sulfonyl|methyl) 2.14a) pyrazol-1-yl phenyl 3,5-

And bisb(idifluorom and od. B-chloro-2-Z,2ai, 58 ethylutn- | UNe snu rn re No ocianomethoxy) 3,23|B) pyrazol-1-yl phenyl 3,5-

Y bisb(idifluorom and od. B-chloro-2-Z,2ai, 59 ethyl)-1H- СНе snu Н сЗ Н Kmethylsulfonyl | C3,25І0I pyrazol-1-yl)oxy|phenyl 3,5- bisidifluorom 4 24. 2-fluoro-6-KE/2)- C,49аі, ethyl)іН- | Ne snu no rez NOI (methoxyimino) | ZIB) pyrazol-1-yl methylphenyl

B-methyl-3-y (trifluorometh ! 24. 2- 3.29Ha), byl)-1H- CH snu and Fe-Z and Kcyclopropylsul | C3,91(OBI pyrazol-1-yl phenyl)oxy|phenyl

B-methyl-3-

І (trifluorometh and od. 2- 3.07ai, 162 ulu-tnsne snu rez NOI dmethylsulfonyl | 2.98B) pyrazol-1-yl )oxy|phenyl 3,5- and bisidifluorom 1 24. zia), 163 ethylutn- | UNe snua rn re NOI ocyanomethoxy) | 2.915) pyrazol-1-yl phenyl 3,5-

And bisidifluorom 4 24. 2- Z,24ai, 64 ethyl)-1H- СNe snu Н Oz Н Kcyclopropylsul | З3,З2(бBI pyrazol-1-yl phenyl)oxy|phenyl 3,5-

And bisidiftorm and one. 2- Z, 1 gai, 165 ethylutn- | UNe snu rn Te NOI (ethylsulfonyl | 3.090) pyrazol-1-yl oxy|phenyl

B-methyl-3- (trifluorometh 4 24. 4-methyl-2- 3,26bai, yl)-THN- CNe snuarn re NOI dmethylsulfonyl 3,21B) pyrazol-1-yl )oxy|phenyl 3,5-

And bisidifluorom 4 24. B-methyl-2-Z,22ai, 67 ethylutn- | UNe snuarn re NOI dmethylsulfonyl 31CB) pyrazol-1-yl)oxy|phenyl 3,5-2-fluoro-6-Kprop- bisidifluorom | СНе сниаТ |н 0-3 Нн 2-yn-1-Z,Z(a) ethyl)-1H-yloxy)methyliphen

Table 1 pa f|I-|x|ha vo || 4 sh i | or oo fprazolt | | ОЙ 71717111 0111111 Г1 3,5- bis(difluorom and 24. 2- ethyl)-ТН- СНе snu un op un (acetoxymethyl)- zga) pyrazol-1-yl b-fluorophenyl 3,5-

And bisidiftorm and one. 4-chloro-2-Z,2ai,

I-7o ethyl)-1H- СНе сну Н сЗ Н Kmethylsulfonyl | C3,27I0I pyrazol-1-yl)oxy|phenyl 3,5-

And bisidiftorm and one. 4-chloro-2-Z,2Zai, 71 ethylutn- | UNe snu rn re NOI cyanomethoxyiu 322IB) pyrazol-1-yl phenyl 3,5-

And bisidifluorom 4 24. 4-methyl-2-Za), 72 ethylutn- | UNe snuarn re NOI dmethylsulfonyl/ 312|B) pyrazol-1-yl)oxy|phenyl 5- (difluorometh

I-7Z3 | yl)-3-methyl-| Snow sleep! |n 0-3 Hn 2- BV 1H-pyrazole-Kmethylsulfonyl and 1-yl)oxy|phenyl 2,5-2- 3,08(a)

I-74 | dimethylphen | MN sleep! |n 0-3 Hn Imethylsulfonyl with OB yl)oxy|phenyl " 3,5-

And bisidifluorom 4 24. 2-chloro-6-Z,19Cai, 75 ethylutn- | UNe snua rn re NOI cyanomethoxyiu ZZITSB) pyrazol-1-yl phenyl 3- (difluoromet 2 "Ia

I-76 | yl)-5-methyl-| СНе снистс |н 0-3 H 2 620) 1H-pyrazole-2-(cyanomethoxy) and 1-yl phenyl 3,5-

And bisidiftorm and one. З- з,о8(а), 77 ethylutn- | UNe snu rn re NOI (ethylsulfonyl | 2.99|B) pyrazol-1-yl oxy|phenyl

B-methyl-3-

І (trifluorometh and od. 2-chloro-6-Z,Z1ai, 78 ulu-tn- СNe snu rn re NOI cyanomethoxy) 3,23|B) pyrazol-1-yl phenyl

B-methyl-3-

Y (trifluorometh 4 24. 2,6-difluoro-3-Z,02ai, 79 il)u-tn- СNe snuarn re NOI dmethylsulfonyl 2,94|B) pyrazol-1-yl )oxy|phenyl 3,5- bis(difluorom 4 24. 2,96(ai, ethyl)iH- | Ne snu no rez NOI zcyanomethoxy)- | 2.85 IB) pyrazol-1-yl 2,6-difluorophenyl 3,5-

And bisb (idiftorm and unit 2.89ai,

VT ethylutn- | UNe snu rn re NOI A (cyanomethoxy) | 28(B) pyrazol-1-yl phenyl -vg|z5- | snfro |snusb ino |z |n |do) buko- | Coincidence),

Table 1 pa f|I-|x|ha vo || what I | or bisidifluorom enoyloxy|phenyl 3,37 ethyl)-1H- pyrazol-1-yl 3,5-

Y bis(difluorom 4 24. З- 3,17ай, /-83 ethyl)-1Н- СНе snu Н Oz Н Kcyclopropylsul | 3,07I0I pyrazol-1-yl phenyl)oxy|phenyl 3,5- 2-

And bisidifluorom 4 24. Kcyclopropylsul | Z,Z2ai,

VA ethylutn- | UNe snua rn Te HO fonyluksyrv- ZiB) pyrazol-1-yl fluorophenyl 3,5-

And bisidiftorm and one. C-fluoro-2- 2.97ai, 85 ethylutn- | UNe snuarn re NOI dmethylsulfonyl 2,91|B) pyrazol-1-yl)oxy|phenyl

B-methyl-3- (trifluorometh and one. 2.94 IB) pyrazol-1-yl b-fluorophenyl 3,5-

And bisidifluorom 4 24. 2.71 Iai, 87 ethylutn- | UNe snua rn re NOI in cyanoethyl 2.646) pyrazol-1-yl 1H-pyrrol-g2-yl 3,5-

And bisidifluorom 4 24. 2-methoxy-6- 3,17ai, 88 ethylutn- | UNe snuarn reny dimethylsulfonyl 3,1CB) pyrazol-1-yl)oxy|phenyl

B-methyl-3- 2-Ш2- (trifluorometh and one methoxyethyl) yl)-1H- СНе sno and ОЗ and sulfinyl|methyl) 2.5ЗЯa) pyrazol-1-yl phenyl 3,5-

And bisidiftorm and one. 4,5-dimethyl-2-Z3,6Zai, 191 ethyl)-1H- CH snu and OZ CHz Kmethylsulfonyl | 3.581 pyrazol-1-yl)oxy|phenyl 3,5-

And bisidifluorom 4 24. 2,3-dimethoxy-6- | Z,28CaY, 92 ethyl)-1H- СНе snu Ноз СНе Kmethylsulfonyl | C3,25I0I pyrazol-1-yl)oxy|phenyl

B-methyl-3- - (trifluorometh 1 24. 2-

I-93 yl)-TH- CHneg sni)a Hn 0-3 Hn Calyloxy)methyl 3,84Ia pyrazol-1-yl phenyl 3,5-

And bisidifluorom and 24. 2-

I-94 ethyl)-1H-СНе sleep and OZ and Kaliloxy)methyli| 3.63a) pyrazol-1-yl phenyl

B-methyl-3-y (trifluorometh 1 24. Z,Ob(a), 195 ul)-thn-sne snua rn re NOI zcyanomethoxy) | 2.97|B) pyrazol-1-yl phenyl

B-methyl-3- (trifluorometh 4 24. 4- 2.9ha, yl)-TH- СНе snuarn re NOI dmethylsulfonyl 2.810) pyrazol-1-yl )oxy|phenyl

Table 1 pa f|I-7|x|ha vo || i | Or

B-methyl-3-

Y (trifluorometh 4 24. 4- Z14Ca), 197 il)-tn- СNe snu rn re NOI (ethylsulfonyl | 3,O5IB) pyrazol-1-yl oxy|phenyl

B-methyl-3- (trifluorometh 4 24. 4- З, 22ай, yl)-1Н- СНе snu Н Oz Н Kcyclopropylsul| 3,13|(0BI pyrazol-1-yl phenyl)oxy|phenyl

B-methyl-3- (trifluorometh 4 24. 3- z, 18 ghai, yl)-TH- CNe snua rn Te NOI (ethylsulfonyl | 3,08IB) pyrazol-1-yl oxy|phenyl 3,5- 2-Ш( 2-

And- | bisbidifluorom and 24. methoxyethyl) 100 | ethyl)-1H- sne snu H cZ H sulfanyl|methyl) 3, 5ia) pyrazol-1-yl phenyl

B-methyl-3-

And- | (trifluorometh and od. 3-Z,25ai, 101) yl)-tH-sne snua rn re NOI dcyclopropylsul 3,12|B) pyrazol-1-yl phenyl)oxy|phenyl 3,5-

And- | bisbidifluorom 4 24. 2-chloro-6-Za), 102| ethyl)-ynH- | УН2 snua rn te NOI dmethylsulfonyl 3,09|B) pyrazol-1-yl)oxy|phenyl

B-methyl-3-

And- | (trifluorometh 4 24. 2-chloro-6-3,28ai, 103)yl)-tH- CNe sne urn 978 NOI dimethylsulfonyl/3,2B)pyrazol-1-yl)oxy|phenyl

B-methyl-3-

And- | (trifluorometh and one.

And- | bisbidifluorom 4 24. 4- 2.97ai, 105 ethyl)inH- | UN2 snua rn Te NOI (ethylsulfonyl | 2.96|B) pyrazol-1-yl oxy|phenyl 3,5-

And- | bisbidiftorm 4 24. 4- Z3.06tsa), 106 | ethyl)in- | UN2 snua rn te NOI dcyclopropylsul 3,05IB) pyrazol-1-yl phenyl)oxy|phenyl 3,5- 2-C(-

And- | bisbidifluorom 4 24. chlorocyclopropyl) | Z, 66 Tsai, 107 | ethyl)in- | UN2 snu rn fe NOI carbonyloxyu 3.57) pyrazol-1-yl phenyl 3.5-

And- | bisbidiftorm and od. 2.42a), 108| ethyluinH- | M snu un oz No. 2.320) pyrazol-1-yl formamidophenyl

B-methyl-3-

And- | (trifluoromet 4 24. 2.49ai, 109 il)-TN- ONe snua un oz no". 2,39) pyrazol-1-yl formamidophenyl

And 3.5-2.95(a) 110 bisidifluorom | Don't sleep! |н 0-3 Нн З-(cyanomethoxy) 2 ВВ(ЛЙ ethyl)-1Н-phenyl"

Table 1 pa f|I-|x|ha vo || i | or oo fpvazolt | HER 11111111

B-methyl-3-

And- | (trifluorometh 4 24. Z,22ai, 111 | il)-tH- sne snu no re NOI o cyanomethoxy)- | Z13(B) pyrazol-1-yl Z-fluorophenyl 3,5-

And- | bisbidiftorm and od. 2- Z,49ai, 112| ethyl)in- | UN2 snu no re NOI dmethylsulfanil | 3,566) pyrazol-1-yl)methoxy|phenyl 3,5-

And- | bisbidiftorm and od. 2.87ai, 113| ethyluin- | SN sleep no rez NOI o cyanomethoxy)- | 2.88(B) pyrazol-1-yl b-fluorophenyl

B-methyl-3- 2-

And- | Trifluorometh 4 24. Cyclopropylsul | Z,43(ai, 114) yl)-tH- sne snua rn Te HO fonyluxir3- Zag) pyrazol-1-yl fluorophenyl 3,5- 2-

And- | bisbidifluorom 4 24. (Ctrifluoromethyl) | 3.92a)|, 115| ethyl)in- | УН2 snu рн re NOI sulfonyluksiu | 3.92|B) pyrazol-1-yl phenyl 3,5-

And- | bisbidiftorm and od. Z,21ai, 116| ethyluin- | SN snu no rez NOI o (acryloyloxy | 3156) pyrazol-1-yl phenyl 3,5-

And- | bisbidifluorom 4 24. 2-Iformyl(prop-2- | 2.65Ca), 117| ethyluin- | SN of sleep from the NO. 2.670) pyrazol-1-yl yl)amino|Ifenyl

B-methyl-3-

And- | (trifluorometh 4 24. 2-fluoro-6-KE/2)- 3.611ai, 118 il)-in snu no rez NOI (methoxyimino) | 396) pyrazol-1-yl methylphenyl

B-methyl-3-

And- | (trifluorometh and unit 2-Z,19Cai, 119) yl)-1H- sne rn re NOI (ethylsulfonyl | 3,21B) pyrazol-1-yl oxy|phenyl

B-methyl-3-

And- | (trifluorometh and od. 2-Z,59ai, 120 | il)-1H- sne snu no rez NOI dmethylsulfanil | 3,596) pyrazol-1-yl)methoxy|phenyl 3,5-

And- | bisbidifluorom 4 24. 2-Cyanomethyl) 2.62a), 121 ethyluin- | CH snua rn fe NOI (formylamine 2,5BIB) pyrazol-1-yl phenyl ore 2,63) 129 bisidifluorom | МН sleep |n 03 IN 2- 2 BMW ethyl)phenyl formamidophenyl " 2,5- ethyl)phenyl formamidophenyl " 3,5-

And- | bisbidiftorm and od. 2- 2.86 Ha), 124| ethyl)inH- | УН2 snu no rez NOI dmethylsulfonyl | 2.86|B) pyrazol-1-yl)oxy|phenyl

Table 1 pi a | 1 mm|x|eivy| about || 4 I | legal

B-methyl-3- 2-

And- | (trifluorometh and od. (Ctrifluoromethyl) | 3.99Cai, 125 | il)u-tn- СНе sna urn 98 NOI sulfonyloxychr! 4) pyrazol-1-yl enyl 3,5-

And- | bisbidiftorm 4 24. 2- Z,11ai, 127| ethyl)inH- | UNg snu no re NOI dimethylcarbamo | 3.066) pyrazol-1-yl thioyl)uphenyl 3,5-

And- | bisbidiftorm 4 24. 2.89ai, 128| ethyluinH- | SN sleep no rez NOI demetoxy-»- | 2870) pyrazol-1-yl oxoethoxy)phenyl 3,5-

And- | bisbidiftorm and od. 2-((3- C,76ai, 129| ethyl)inH- | UN2 snu rn fe NOI fluorobenzoyloxy 3,7) pyrazol-1-yl phenyl 3,5-

And- | bisbidiftorm and od. 2-(2-3,611ai, 130| ethyl)inH- | UN2 snu rn fe NOI fluorobenzoyloxy 3,5VIB) pyrazol-1-yl phenyl 3,5-

And- | bisbidifluorom 4 24. 2- Z3,69ai, 134 | ethyluin- | UN2 snu no re NOI (benzoyloxy)pheny | 3.656) pyrazol-1-yl l 3,5-

And- | bisbidifluorom 4 24. 2-(4-Z,7Zai, 132 ethyl)inH- | CH sne un fo NOI fluorobenzoyloxy) 3,7) pyrazol-1-yl phenyl 3,5-

And- | bisbidiftorm and od. 2- 4.78Ia), 133 ethyl)in-| Н2 snu рн re NOI dtrimethylsilyl | 4,79(B) pyrazol-1-yl phenyl|phenyl 3,5-

And- | bisbidiftorm 1 24. 134 | ethyl)-1H- snia Hn Oz |H 2,63Ca) pyrazol-1-yl 2-carboxyphenyl 3,5-

And- | bisbidifluorom 4 24. 135 ethyl)-1H- snia SI Oz |H 3.09ha) pyrazol-1-yl 2-carboxyphenyl 3,5-

And- | bisbidiftorm and od. 2- 2.84Tsa), 136| ethyluin- | CN sleep no rez NOI detylcarbamoyl | 2.816) pyrazol-1-yl oxy|phenyl 3,5-

And | bisidifluorom and 24. 3-(3-(1- 4,6(a), 137| ethyl)in- | UN2 snu rn Te NOI naphthyluprop-o-in- 4,716) pyrazol-1-yl 1-ilyoxy)phenyl 3 ,5-

And- | bisbidifluorom and by 2-Kprop-2-yn-1- 138 | ethyl)-TH- sne snua un on yloxy)methyl|phen Z,7aa) pyrazol-1-yl yl 1 35- 2- bisidifluorom | Don't sleep! |n 0-1 Nn Calyloxi)methyl| | 4,11ai 139: ethyl)-1H-phenyl

Table 1 pa f|I-|x|ha vo || i | or oo fprazolyi | Her number is 71111111

B-methyl-3-

And- | (trifluorometh 4 24. 2.97ai, 140 | il)-1H- sne snu no re NOI ocyanomethoxy) | 2.98|B) pyrazol-1-yl phenyl 3,5-

And- | bisbidiftorm and od. 3.17ai, 141 | ethyl)in- | УН2 snu no rez NOI o cyanomethoxy)- | ZY15B) pyrazol-1-yl β-methylphenyl

B-methyl-3-

And- | (trifluorometh and od. Z,29ai, 142) yl)-TN- sne snu rn re NOI oscyanomethoxy)- | 3,22|B) pyrazol-1-yl 4-methylphenyl 5-

I- (difluorometh 2.6bIa 143 il)-3-methyl- | СНе снистс |н 0-3 H 2 610) 1H-pyrazole-2-(cyanomethoxy) and 1-yl phenyl 3,5-

And- | bisbidiftorm and od. Z, 15ai, 144| ethyl)inH- | УН2 snu no rez NOI o cyanomethoxy)- | ZIB) pyrazol-1-yl 4-methylphenyl 3,5-

And- | bisbidiftorm and od. Z-chloro-2-Z,19Cai, 145| ethyluin- | CH sleep no rez NOI dmethylsulfonyl | 3,196) pyrazol-1-yl)oxy|phenyl 3,5-

And- | bisbidifluorom 4 24. Z-chloro-2-Za, 146| ethyluin- | SN sne no rez NOI (cyanomethoxy) | C26(B) pyrazol-1-yl phenyl

Determination of IODR-values is carried out according to the instructions of "EES bOigesiime 79/831 Appeh M.AV8" using HPLC (high-performance liquid chromatography), using columns (C 18) with the reverse phase under the following conditions: and LC-MS determinations were carried out in an acidic environment at pH 2.7, using a 0.1 95 aqueous solution of formic acid and acetonitrile (containing 0.1 95 formic acid) as eluents; linear gradient from 10 95 acetonitrile to 95 95 acetonitrile.

IB determination by LC-MS in a neutral environment was carried out at pH 7.8, using a 0.001 molar aqueous solution of ammonium bicarbonate and acetonitrile as eluents; linear gradient from 10 95 acetonitrile to 95 95 acetonitrile.

Calibration is carried out with the help of unbranched alkan-2-ones (3 3 - 16 carbon atoms), for which IosdR values are known (IosdR values are determined by determining the retention time by linear interpolation between the two determined alkanones).

The maximum values of lambda were determined in the maximum of the chromatographic signals when identified by the UV spectrum in the range from 200 nm to 400 nm.

NMR data of selected examples

List of NMR peaks "H-NMR data of Examples 1-1 - I-146 are given in the form of a list of "H NMR peaks. For each signal peak, the b value in ppm and the signal intensity are given in parentheses:

Pr. I-1, solvent: DMSO-аv, spectrometer: 399.95 MHz 8.005 (13.37); 7.345 (1.55); 7,341 (1.61); 7.323 (7.96); 7.304 (7.53); 7.167 (5.14); 7.153 (2.96); 7.148 (3.78); 7.126 (2.78); 7,034 (2.69); 7.024 (2.75); 7.017 (6.01); 7.004 (3.48); 6.987 (1.61); 6.897 (4.65); 6,881 (2.74); 5.883 (1.89); 5.865 (2.48); 5.856 (2.07); 5.836 (1.89); 5.398 (3.89); 5.362 (3.89); 4.88 (16); 4.358 (1.19); 4.324 (1.91); 3.978 (1.29); 3.939 (1.24); 3.887 (1.85); 3.859 (2.11); 3.844 (2.68); 3.816 (2.21); 3.454 (2.01); 3.439 (2.68); 3.385 (7.91); 3,295 (195); 3,264 (12); 3.247 (8.9); 5.228 (7.21); 3.191 (2.87); 3.144 (1.82); 3.131 (1.59); 3.113 (1.44); 3.084 (1.25); 2.991 (1.26); 2,859 (112); 2.831 (1.74); 2.795 (1.4); 2.673 (6.53); 2,669 (8.4); 2.664 (6.37); 2.659 (3.12); 2.546 (3.11); 2.539 (8.93); 2.522 (31.18); 2,509 (503,82); 2,504 (961,34); 2.5 (1273.83); 2,495 (886.2); 2,491 (426.02); 2.381 (1.77); 2.349 (1.44) in; 2.331 (7.07); 2.326 (9.44); 2.322 (6.76); 2,119 (1.5); 2.087 (2.62); 2.077 (1.99); 2.067 (12.61); 1.796 (1.22); 1.777 (1.35); 1.568 (1.25); 1.543 (1.5); 1.234 (1.88); 0.889 (1.24); 0.131 (5.23); 0.123 (131.29); 0.114 (5.54); 0.007 (3.28); -0.001 (79.32); -0.01 (3.18

Pr. I-2, solvent: ДдМСО-ав, spectrometer: 399.95 MHz 8.0349 (2.32); 8.0143 (2.67); 7.9888 (3.94); 7.971 (6.53); 7.9525 (4.1); 7.9375 (1.41); 7.9264 (13.19); 7.1492 (0.33); 7.6789 (3.85); 7.6634 (4.51); 7.6609 (4.65); 7.6295 (0.5); 7.6132 (0.81); 7.609 (0.75); 7.5927 (0.6); 7.577 (1.52); 7.5636 (2.9); 7.5596 (3.1); 7.5452 (5.03); 7.5405 (4.82); 7.5251 (3.38); 7.5197 (4.66); 7.5131 (2.25); 7.5083 (2.27); 7.5014 (4.06); 7.499 (4.14); 74808 (2.9); 7.4754 (1.21); 7.4189 (1.17); 7.4025 (2.65); 7.3983 (3.37); 7.37 71 (8.65); 7.3738 (8.25); 7.3564 (5.54); 7.2978 (2.49); 7.256 (1.35); 7.2402 (0.59); 7.2221 (0.81); 7.1646 (5.4); 7.1561 (2.99); 7.1227 (0.71); 7.0961 (1.59); 7.0873 (1.71); 7.0708 (2.01); 7.051 (3.31); 7.0313 (4.39); 7.02 (6.42); 6.9518 (0.82); 6.8976 (5.36); 6.8842 (3.17); 5.9693 (2.15); 5.9509 (2.49); 5.9414 (2.54); 5.9235 (2.42); 5.9057 (1.28); 5,899 (1.5); 5.872 (0.32); 5.8269 (1.37); 5.8208 (1.25); 5.746 (9.66); 5.4515 (0.34); 5.4366 (0.91); 5.422 (0.9); 5.3835 (4); 5.3501 (4.08); 5.3315 (0.74); 5.3058 (16); 4.4691 (1.25); 4.4538 (1.26); 4.3174 (1.33); 4.2876 (1.31); 4.0393 (0.52); 4.0213 (0.5); 3.9344 (3.2); 3.9065 (3.57); 3.8918 (3.44); 3.8639 (2.92); 3.3683 (5.86); 3.35 (9.97); 3.93127 (5023.01); 3.2892 (60.61); 3.2639 (7); 3.2557 (5.62); 3.1855 (1.84); 3.1289 (0.83); 3.1104 (0.79); 3.0495 (0.69); 2.9549 (0.75); 2.8123 (1.11); 2.7832 (1.67); 2.7555 (1.11); 2.6954 (0.65); 2.6743 (3.39); 2.6697 (4.51); 2.665 (3.39); 2.6605 (1.8); 2.5397 (5.62); 2,523 (17.04); 2.5096 (244.58); 2.5052 (462.71); 2.5007 (610.99; 2.4962 (422.42); 2.4918 (202.13); 2.332 (3.2); 2.3273 (4.27); 2.3228 (3.09) ; 2.3183 (1.57); 2.0691 (8.81); 2.0415 (1.47); 2.0085 (2.08); 1.9868 (2.82); 1.9634 ( 1.39); 1.7523 (0.55); 1.7219 (1.09); 1.701 (1.06); 1.6712 (0.52); 1.5759 (0.51); 1, 4857 (1.08); 1.4559 (1); 1.3524 (1.08); 1.3358 (0.37); 1.2983 (1.56); 1.2589 (2.23); 1.2361 (3.05); 1.1927 (0.66); 1.175 (1.23); 1.1571 (0.69); 0.89 (0.59); 0.8533 (0.44 ); 0.008 (2.29); -0.0002 (51.39); -0.0085 (1.82

Pr. I-3, solvent: DMSO-аv, spectrometer: 399.95 MHz 8.2255 (0.34); 8.0363 (0.44); 8.0293 (6.02); 7.8714 (0.34); 7.6806 (1.86); 7.6257 (0.63); 7.6199 (0.88); 7.6157 (0.67); 7.6099 (0.70); 7.6039 (1.17); 7.5990 (0.72); 7.4969 (0.34); 7.4596 (0.46); 7.4473 (0.53); 7.4404 (1.80); 7.4340 (1.01); 7.4306 (1.41); 7.4247 (3.00); 74116 (0.37); 7.4076 (0.45); 6.4911 (3.23); 5.8063 (0.72); 5.7854 (0.89); 5.7 791 (0.90); 5.7582 (0.81); 5.7468 (3.81); 5.3409 (0.55); 5.2982 (1.94); 5.2492 (1.88); 5.2067 (0.55); 4.3848 (0.54); 4.3516 (0.57); 3.9894 (0.62); 3.9556 (0.60); 3.9367 (0.99); 3.9192 (16.00); 3.9094 (1.27); 3.9034 (0.42); 3.8936 (1.28); 3.8826 (1.28); 3.8664 (0.89); 3.7171 (2.75); 3.4160 (0.46); 3.4094 (1.34); 3.3999 (0.43); 3.3886 (1.36); 3.3815 (0.96); 3.3728 (0.78); 3.3662 (1.14); 3.3526 (0.82); 3.3455 (1.26); 3.3050 (177.27); 3.2408 (0.53); 2.8714 (0.38); 2.8423 (0.65); 2.8144 (0.38); 2.5941 (0.68); 2.5225 (1.01); 2.5091 (16.66); 2.5048 (31.74); 2.5003 (42.04); 2.4959 (29.42); 24915 (14.34); 2.2096 (12.18); 2.1849 (15.17); 2.1447 (0.63); 2.1334 (3.19); 2.1023 (1.10); 2.0695 (0.70); 1.9868 (0.71); 1.8227 (0.46); 1.8162 (0.49); 1.7935 (0.45); 1.7863 (0.42); 1.5881 (0.42); 1.5792 (0.47); 1.5572 (0.43); 1.5498 (0.42); 1.1751 (0.40); 0.0080 (0.32); -0.0002 (8.13); -0.0085 0.37

Pr. I-4, Solvent: dmeoo-ab, spectrometer: 399.95 MHz 11.4475 (1.50); 8.3876 (1.40); 8.0357 (1.80); 7.6994 (0.38); 7.6810 (0.46); 7.6770 (0.41); 7.4509 (0.52); 7.4115 (0.47); 7.4076 (0.42); 7.3929 (0.38); 7.3890 (0.56); 7.3847 (0.38); 7.3709 (0.39); 7.3666 (0.37); 7.1703 (0.71); 7.1571 (0.37); 7.0370 (0.37); 7.0211 (0.82); 6.8974 (0.72); 6.8852 (0.41); 5.4044 (0.53); 5.3633 (0.55); 3.9706 (0.43); 3.9426 (0.51); 3.9272 (0.45); 3.8986 (16.00); 2.5395 (0.43); 2.5091 (7.68); 2.5049 (13.81); 2.5004 (17.31); 2.4961 (11.67); 2.4919 (5.43); 2.0911 (0.33); 0.0079 0.40); -0.0002 (7.85); -0.0084 (0.35 bo

Pr. I-5, Solvent: dmeoo-ab, spectrometer: 399.95 MHz 8.2203 (0.42); 8.0298 (6.06); 7.8575 (0.41); 7.6788 (2.33); 7.6294 (0.78); 7.6242 (1.17); 7.6199 (0.82); 7.6131 (0.87); 7.6075 (1.46); 7.6028 (0.87); 7.4649 (0.33); 7.4559 (0.73); 7.4369 (2.23); 7.4201 (3.77); 7.4057 (0.55); 7.4014 (0.59); 7.3082 (1.17); 7.1749 (2.62); 7.1595 (1.95); 7.0416 (1.30); 7.0235 (2.98); 6.9007 (2.84); 6.8876 (1.56); 5.8054 (0.86); 5.7846 (1.12); 5.7786 (1.13); 5.7575 (1.04); 5.7464 (4.36); 5.4519 (0.56); 5.4095 (2.13); 5.3685 (2.12); 5.3260 (0.57); 4.3648 (0.65); 4.3313 (0.67); 4.2053 (1.34); 4.1878 (4.14); 4.1702 (4.23); 4.1567 (0.66); 4.1526 (1.47); 4.1394 (0.41); 3.9905 (0.92); 3.9731 (0.87); 3.9552 (0.76); 3.9501 (0.74); 3.9357 (1.15); 3.9083 (1.05); 3.9000 (0.33); 3.8925 (1.19); 3.8653 (1.00); 3.4149 (1.64); 3.4063 (0.53); 3.3942 (1.66); 3.3868 (1.15); 3.93717 (1.47); 3.3510 (1.59); 3.3120 (149.30); 3.2889 (2.03); 3.2714 (1.25); 3.2414 (0.64); 2.8726 (0.44); 2.8437 (0.79); 2.8155 (0.47); 2.5096 (10.67); 2.5055 (19.23); 2.5011 (24.54); 2.4968 (17.42); 2.1887 (16.00); 2.1398 (2.51); 2.1019 (1.27); 2.0696 (0.88); 1.8123 (0.58); 1.7904 (0.52); 1.7826 (0.51); 1.5920 (0.52); 1.5830 (0.57); 1.5617 (0.52); 1.5527 (0.51); 1.2762 (4.39); 1.2586 (9.31); 1.2411 (5.10); 1.2237 (0.52); 1.1276 (0.56); 1.1101 1.06); 1.0926 (0.53); -0.0002 (4.76

Pr. I-6, Solvent: dmeoo-ab, spectrometer: 399.95 MHz 8.2112 (4.94); 8.0300 (6.23); 7.6464 (2.58); 7.5793 (0.83); 7.5749 (1.24); 7.5622 (0.99); 7.5576 (1.58); 7.4920 (0.37); 7.4642 (0.96); 7.4452 (2.22); 7.4263 (3.32); 7.4109 (0.42); 7.4063 (0.48); 7.3064 (1.16); 7.1731 (2.62); 7.1583 (1.27); 7.0398 (1.91); 7.0223 (2.84); 6.8997 (2.72); 6.8865 (1.43); 5.8012 (0.94); 5.7802 (1.17); 5.7740 (1.13); 5.7533 (0.95); 5.4496 (0.56); 5.4075 (2.04); 5.3665 (2.04); 5.3241 (0.55); 4.4215 (0.54); 4.4060 (1.26); 4.3903 (1.76); 4.3748 (1.56); 4.3594 (1.12); 4.3288 (0.70); 4.0572 (0.56); 4.0394 (1.62); 4.0216 (1.61); 4.0038 (0.68); 3.9822 (0.72); 3.9412 (1.47); 3.9138 (1.22); 3.8982 (1.91); 3.8708 (1.09); 3.5679 (0.50); 3.4153 (1.21); 3.4001 (2.25); 3.3851 (2.22); 3.3795 (2.81); 3.3569 (3.92); 3.3148 (658.64); 3.2918 (6.91); 3.2418 (0.69); 2.8907 (0.34); 2.8743 (0.46); 2.8446 (0.81); 2.8155 (0.47); 2.6744 (0.48); 2.6701 (0.63); 2.6654 (0.48); 2.5400 (1.33); 2.5095 (37.46); 2.5054 (66.87); 2.5010 (85.26); 2.4966 (60.21); 2.3323 (0.44); 2.3278 (0.56); 2.3231 (0.41); 22095 (0.42); 2.1358 (0.61); 2.1001 (1.24); 2.0691 (1.44); 1.9869 (6.63); 1.9084 (0.88); 1.8114 (0.58); 1.7888 (0.50); 1.7822 (0.49); 1.5819 (0.55); 1.5593 (0.53); 1.5515 (0.51); 1.3982 (10.17); 1.2507 (15.93); 1.2430 (2.56); 1.2351 (16.00); 1.2079 (1.21); 1.1929 (2.39); 1.1752 (3.65); 1.1574 (1.80); -0.0002 (5.85

Pr. I-7, Solvent: dmeoo-ab, spectrometer: 399.95 MHz 11.2056 (1.20); 8.0268 (1.15); 7.6787 (0.48); 7.4173 (0.42); 7.3986 (0.35); 7.3870 (0.40); 6.4917 (0.65); 5.2982 (0.39); 5.2497 (0.40); 3.5677 (16.00); 3.4040 (0.34); 3.3837 (0.45); 3.3608 (0.45); 3.3408 (0.65); 3.3069 (81.01); 3.2838 (0.74); 2.5090 (7.15); 2.5047 (12.74); 2.5003 (16.18); 2.4960 11.30); 2.4918 (5.50); 2.2093 (2.48); 2.1556 (3.12); 2.1151 (0.34); -0.0002 (3.14

Pr. I-8, Solvent: dmeoo-ab, spectrometer: 399.95 MHz 8.2111 (1.53); 8.0300 (2.04); 7.6461 (0.78); 7.5744 (0.39); 7.5572 (0.49); 7.4631 (0.38); 7.4442 (0.69); 7.255 (1.08); 6.4914 (1.24); 5.7800 (0.36); 5.7729 (0.37); 5.2986 (0.72); 5.2489 (0.74); 4.4056 (0.42); 4.3900 (0.70); 4.3745 (0.57); 4.3587 (0.35); 3.9412 (0.40); 3.9137 (0.36); 3.8981 (0.41); 3.8705 (0.34); 3.5679 (16.00); 3.4000 (0.63); 3.3905 (0.41); 3.3800 (0.83); 3.3722 (0.51); 3.3567 (0.76); 3.3363 (1.14); 3.3073 (112.05); 3.2843 (1.25); 2.5395 (0.39); 2.5092 (10.10); 2.5050 (18.11); 2.5006 (23.17); 2, A963 (16,44); 2.2094 (4.58); 2.1016 (0.45); 2.0696 (0.92); 1.2505 (4.98); 1.2425 (1.00); 1.2349 5.00); 1.2272 (0.76); 1.2238 (0.66); 1.2082 (0.81); 1.1929 (0.41); -0.0002 (4.41

Pr. I-9, Solvent: dmeoo-ab, spectrometer: 399.95 MHz 8.0292 (1.29); 7.6737 (0.49); 7.6096 (0.32); 7.4312 (0.51); 7.4130 (0.83); 6.4910 (0.86); 5.2982 (0.51); 5.2484 (0.51); 4.3884 (0.43); 4.3730 (0.35); 3.5678 (16.00); 3.3966 (0.935); 3.3809 (0.32); 3.3739 (0.41); 3.3534 (0.50); 3.3081 (83.29); 2.5048 (12.70); 2.5005 (16.04); 2.4962 (11.34); 2.2091 (3.22); 2.1735 (3.27); 2.1412 (0.90); 2.1024 (0.33); 1.2594 (3.44); 1.2438 (3.53); 1.0976 (0.45); 1.0948 (0.43); 1.0821 (0.44); 1.0792 (0.41); -0.0002 (3.04)

Pr. I-10, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 11.2428 (0.89); 8.1528 (0.72); 8.0288 (0.97); 7.6213 (0.36); 7.4263 (0.33); 7.3967 (0.32); 6.4914 (0.53); 5.2500 (0.32); 3.5678 (16.00); 3.3820 (0.33); 3.3074 (37.10); 2.5092 (3.26); 2.5049 (5.96); 2.5005 (7.72); 2.4961 (5.50); 2.4918 (2.78); 2.2096 (2.00); 1.3980 (0.45); -0.0002 (1.52

Pr. I-11, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.2454 (2.15); 8.0295 (2.68); 7.6513 (1.09); 7.5775 (0.35); 7.5727 (0.51); 7.5611 (0.42); 7.5561 (0.67); 7.5518 (0.41); 7.5070 (0.58); 7.4691 (0.56); 7.4479 (0.98); 7.4308 (1.65); 6.4916 (1.83); 5.8026 (0.42); 5.7821 (0.52); 5.7751 (0.56); 5.7551 (0.43); 5.3417 (0.33); 5.2989 (1.09); 5.2494 (1.09); 4.3838 (0.34); 4.3512 (0.36); 4.1861 (0.75); 4.1685 (2.26); 4.1509 (2.30); 4.1333 (0.78); 3.9899 (0.35); 3.9544 (0.41); 3.9433 (0.61); 3.9155 (0.54); 3.8999 (0.59); 3.8725 (0.50); 3.5680 (16.00); 3.4106 (0.44); 3.3986 (0.89); 3.3907 (0.59); 3.3785 (1.09); 3.3715 (0.74); 3.3551 (1.14); 3.3348 (1.68); 3.3091 (111.71); 32706 (0.60); 2.8446 (0.41); 2.5398 (0.42); 2.5093 (10.38); 2.5052 (18.38); 2.5008 (23.22); 2.4965 (16.28); 2.2097 (6.81); 2.1032 (0.66); 2.0696 (0.50); 1.3980 (0.51); 1.2645 (1.99); 1.2580 (0.40); 1.2469 (4.10); 1.2401 (1.01); 1.2293 (2.05); 1.2222 (1.13); 1.2046 (0.45); -0.0002 (4.93

Pr. I-12, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.2454 (5.31); 8.2217 (0.33); 8.1295 (3.42); 8.0232 (6.26); 7.9510 (0.55); 7.6550 (2.75); 7.5784 (0.84); 7.5733 (1.18); 7.5695 (0.91); 7.5624 (1.02); 7.5572 (1.59); 7.5529 (1.03); 7.5074 (1.20); 7.4880 (0.49); 7.4700 (1.12); 7.4674 (1.12); 7.4480 (2.43); 7.4319 (4.12); 7.4183 (0.48); 7.4142 (0.45); 7.3361 (3.28); 7.3306 (3.21); 7.1979 (2.27); 71774 (3.10); 7.0828 (2.25); 7.0772 (2.13); 7.0624 (1.60); 7.0569 (1.51); 5.8026 (1.04); 5.7933 (0.38); 5.7822 (1.30); 5.7752 (1.41); 5.7657 (0.47); 5.7546 (1.38); 5.7472 (7.43); 4.1867 (2.48); 4.1693 (6.60); 4.1516 (6.46); 4.1407 (2.51); 4.1342 (3.07); 3.9451 (1.08); 3.9176 (1.22); 3.9019 (1.39); 3.8745 (1.18); 3.4180 (0.35); 3.4022 (1.38); 3.3819 (1.38); 3.3749 (0.58); 3.3589 (1.72); 3.3385 (2.32); 3.3148 (83.57); 3.0401 (1.25); 3.0107 (2.31); 2.9816 (1.27); 2.5065 (19.91); 2.5022 (16.67); 2.4980 (11.78); 2.1571 (16.00); 2.0938 (1.62); 2.0675 (1.82); 1.9881 (1.20); 1.7208 (0.55); 1.7113 (0.66); 1.6899 (1.37); 1.6817 (1.51); 1.6595 (1.42); 1.6513 (1.34); 1.6299 (0.58); 1.6202 (0.47); 1.2650 (4.75); 1.2474 (9.74); 1.2413 (2.28); 1.2298 (5.01); 1.2234 (2.47); 1.2124 (0.38); 1.2057 (0.99); 1.1938 (0.45); 1.1760 (0.73); 1.1582 (0.38); -0.0002 (3.31

Pr. I-13, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.2111 (5.03); 8.1293 (2.96); 8.0235 (6.16); 7.6504 (2.64); 7.5800 (0.81); 7.5754 (1.22); 7.5717 (0.87); 7.5633 (0.99); 7.5586 (1.58); 7.4921 (0.47); 7.4633 (1.01); 7.4443 (2.26); 7.4267 (3.96); 7.120 (0.49); 7.4078 (0.51); 7.3364 (2.77); 7.3309 (2.75); 7.1977 (1.94); 7.1772 (2.65); 7.0825 (1.92); 7.0770 (1.83); 7.0622 (1.38); 7.0567 (1.30); 5.8005 (0.97); 5.7800 (1.23); 5.7733 (1.25); 5.7472 (7.50); 4.4221 (0.50); 4.4065 (1.23); 4.3909 (1.67); 4.3753 (1.27); 4.3598 (0.53); 41749 (1.61); 4.1415 (1.69); 3.9435 (0.97); 3.9160 (1.11); 3.9087 (0.33); 3.9004 (1.26); 3.8730 (1.07); 3.4042 (1.26); 3.3838 (1.26); 3.3610 (1.47); 3.3405 (1.86); 3.9151 (73.83); 3.0403 (1.07); 3.0108 (1.99); 2.9817 (1.11); 2.5067 (11.15); 2.5023 (14.01); 2.4981 (9.96); 2.1573 (13.70); 2.0941 (1.39); 2.0675 (1.56); 1.9882 (1.13); 1.7209 (0.47); 1.7116 (0.57); 1.6899 (1.19); 1.6818 (1.91); 1.6596 (1.23); 1.6517 (1.15); 1.6300 (0.50); 1.6205 (0.40); 1.2508 (15.93); 1.2352 (16.00); 1.2241 (1.49); 1.2162 (0.70); 1.2082 (1.52); 1.1996 (0.44); 1.1933 0.98); 1.1762 (0.79); 1.1586 (0.40); -0.0002 (2.77

Pr. I-14, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 11.2471 (7.55); 8.1550 (6.46); 8.1286 (3.47); 8.0228 (7.62); 7.6253 (3.32); 7.5582 (1.70); 7.5400 (2.19); 7.4462 (1.16); 7.4272 (2.87); 7.4088 (2.37); 7.3989 (2.92); 7.3833 (0.77); 7.3795 (1.03); 7.3360 (3.22); 7.3306 (3.33); 7.1985 (2.28); 71780 (3.06); 7.08391 (2.22); 7.0775 (2.14); 7.0628 (1.60); 7.0571 (1.54); 5.7900 (1.20); 5.7701 (1.50); 5.7628 (1.51); 5.7463 (11.33); 4.1748 (1.81); 4.1413 (1.93); 4.0400 (0.72); 4.0223 (0.73); 3.9396 (1.21); 3.9121 (1.39); 3.8965 (1.60); 3.8690 (1.34); 3.4056 (1.53); 3.3857 (1.59); 3.3624 (1.83); 3.3563 (1.15); 3.3425 (2.45); 3.3179 (124.78); 3.0397 (1.28); 3.0100 (2.34); 2.9816 (1.27); 2.5104 (9.19); 2.5064 (16.43); 2.5020 (20.93); 2.4977 (14.95); 2.1849 (1.42); 2.1571 (16.00); 2.0955 (1.63); 2.0699 (1.85); 1.9877 (3.08); 1.7205 (0.55); 1.7111 (0.66); 1.6895 (1.97); 1.6814 (1.53); 1.6591 (1.44); 1.6513 (1.36); 1.6296 (0.60); 1.6198 (0.50); 1.2352 (0.36); 1.1934 0.89); 1.1757 (1.70); 1.1579 (0.86); -0.0002 (4.38

Pr. I-15, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.2524 (1.54); 8.0295 (1.88); 7.6545 (0.75); 7.5707 (0.932); 7.5550 (0.43); 7.4517 (0.70); 7.4418 (0.55); 7,AZ361 (1.12); 6.4917 (1.15); 5.7840 (0.36); 5.7769 (0.35); 5.2985 (0.71); 5.2494 (0.69); 3.9446 (0.46); 3.9202 (0.85); 3.8954 (5.35); 3.8827 (0.44); 3.8739 (0.40); 3.5680 (16.00); 3.3971 (0.56); 3.3888 (0.38); 3.3769 (0.67); 3.3537 (0.76); 3.3333 (1.14); 3.3086 (89.54); 3.2860 (0.90); 2.5093 (7.51); 2.5051 (13.45); 2.5007 (17.10); 2.4964 (12.03); 2.2096 (4.32); 2.1026 (0.43); 2.0695 (0.34); -0.0002 322

Pr. I-16, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.2528 (1.39); 8.0301 (1.70); 7.6547 (0.67); 7.5552 (0.39); 7.4521 (0.62); 7.4422 (0.49); 7.4365 (1.02); 7.3071 (0.34); 7.1737 (0.78); 7.1590 (0.40); 7.0403 (0.39); 7.0229 (0.89); 6.8996 (0.85); 6.8870 (0.46); 5.4081 (0.63); 5.3674 (0.62); 3.9446 (0.48); 3.9203 (0.80); 3.8955 (4.80); 3.8833 (0.52); 3.8738 (0.36); 3.5678 (16.00); 3.3972 (0.57); 3.3867 (0.46); 3.3771 (0.61); 3.3652 (0.34); 3.3542 (0.61); 3.3338 (0.82); 3.3044 (95.90); 3.2808 (1.43); 2.5089 (9.49); 2.5047 (16.71); 2.5003 (21.05); 2.4960 (14.54); 2.1017 (0.36); 2.0694 (0.33); 0.8730 (0.49); -0.0002 (0.38

Pr. I-17, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 9.9019 (0.59); 9.3682 (0.40); 8.6466 (0.58); 8.0108 (1.20); 7.4693 (0.62); 7.4478 (0.71); 7.2845 (0.78); 7.2630 (0.63); 7.1750 (0.67); 7.1594 (0.39); 7.0420 (0.33); 7.0232 (0.81); 6.8995 (0.83); 6.8874 (0.44); 5.7466 (6.07); 5.4093 (0.56); 5.3679 (0.48); 4.0392 (0.70); 4.0214 (0.72); 3.3669 (0.39); 3.3448 (0.49); 3.3071 (72.47); 2.5655 (16.00); 2.5089 (8.92); 2.5047 (16.11); 2.5003 (20.62); 2.4960 (14.55); 1.9868 2.99); 1.4704 (8.58); 1.4611 (1.50); 1.1928 (0.83); 1.1750 (1.63); 1.1572 (0.80); -0.0002 (0.32

Pr. I-18, Solvent: dmeoo-ab, spectrometer: 399.95 MG 11.2052 (1.60); 8.0276 (1.56); 7.6793 (0.69); 7.6079 (0.38); 7.5893 (0.44); 7.4179 (0.60); 7.3993 (0.50); 7.3876 (0.58); 7.1738 (0.67); 7.1591 (0.34); 7.0404 (0.33); 7.0230 (0.75); 6.8995 (0.73); 6.8871 (0.39); 5.4082 (0.52); 5.3680 (0.54); 3.8912 (0.34); 3.5676 (16.00); 3.4048 (0.46); 3.3851 (0.61); 3.3765 (0.34); 3.3615 (0.52); 3.3416 (0.62); 3.3042 (61.97); 2.5087 (8.10); 2.5046 (14.17); 2.5002 17.74); 2.4959 (12.30); 2.1562 (4.29); 2.1019 (0.34); -0.0002 (1.31

Pr. I-19, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.2519 (4.74); 8.1286 (2.53); 8.0227 (5.51); 7.6570 (2.37); 7.57 70 (0.68); 7.5708 (0.94); 7.5674 (0.83); 7.5616 (0.85); 7.5557 (1.27); 7.5512 (0.90); 7.4710 (0.59); 7.4518 (2.13); 7.4431 (1.70); 7.4368 (3.43); 7.4244 (0.43); 7.4203 (0.37); 7.3345 (2.45); 7.3291 (2.43); 7.1982 (1.68); 7.1777 (2.30); 7.0829 (1.68); 7.0774 (1.61); 7.0626 (1.21); 7.0570 (1.16); 5.8039 (0.89); 5.7836 (1.11); 5.7767 (1.09); 5.7561 (1.12); 5.7460 (8.59); 4.1737 (1.39); 4.1402 (1.46); 4.0401 (0.36); 4.0224 (0.36); 3.9463 (0.97); 3.9188 (1.29); 3.8961 (16.00); 3.8846 (1.24); 3.8758 (1.23); 3.4001 (1.21); 3.3798 (1.28); 3.3567 (1.73); 3.3363 (2.99); 3.3185 (111.23); 3.0394 (0.94); 3.0100 (1.72); 2.9814 (0.94); 2.5105 (7.01); 2.5064 (12.49); 2.5020 (15.88); 2.4977 (11.27); 2.1563 (11.94); 2.0942 (1.20); 2.0699 (1.39); 1.9877 (1.50); 1.7203 (0.40); 1.7104 (0.49); 1.6889 (1.02); 1.6805 (1.13); 1.6585 (1.05); 1.6506 (0.99); 1.6290 (0.42); 1.6195 0.35); 1.1936 (0.42); 1.1758 (0.82); 1.1580 (0.41); -0.0002 (2.14

Pr. I-20, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0301 (2.82); 7.6749 (1.03); 7.6323 (0.36); 7.6274 (0.55); 7.6232 (0.34); 7.6154 (0.41); 7.6102 (0.69); 7.6056 (0.49); 7.4511 (0.37); 7.4320 (1.07); 7.4137 (1.71); 7.3067 (0.54); 7.1733 (1.21); 7.1585 (0.63); 7.0402 (0.60); 7.0224 (1.38); 6.8992 (1.33); 6.8865 (0.72); 5.8022 (0.39); 5.7816 (0.54); 5.7754 (0.47); 5.7544 (0.47); 5.4081 (0.97); 5.3671 (0.97); 4.4046 (0.53); 4.3890 (0.75); 4.3733 (0.69); 4.3579 (0.48); 4.3269 (0.46); 4.3238 (0.46); 3.9489 (0.34); 3.9327 (0.56); 3.9054 (0.55); 3.8896 (0.63); 3.8625 (0.53); 3.5678 (16.00); 3.4175 (0.72); 3.4084 (0.39); 3.3971 (0.84); 3.3867 (0.64); 3.3749 (0.81); 3.3666 (0.52); 3.3543 (0.89); 3.3472 (0.66); 3.3058 (124.65); 3.2822 (1.98); 2.8447 (0.37); 2.5394 (0.40); 2.5090 (11.83); 2.5047 (21.08); 2.5003 (26.82); 2.4960 (18.64); 2.4918 (9.05); 2.1740 (7.20); 2.1418 (1.65); 2.1339 (0.43); 2.1015 (0.58); 2.0847 (0.51); 2.0693 (0.49); 1.2598 (7.58); 1.2442 (7.81); 1.2275 (0.60); 1.1747 (0.43); 1.1589 (0.40); 1.0980 (0.79); 1.0949 (0.74); 1.0826 (0.77); 1.0794 (0.71); - 0.0002 (0.61

Pr. I-21, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0302 (1.75); 7.6812 (0.61); 7.6044 (0.36); 7.4412 (0.61); 7.4313 (0.50); 7.4253 (0.97); 7.3071 (0.33); 7.1737 (0.73); 7.1590 (0.38); 7.0405 (0.37); 7.0229 (0.82); 6.8996 (0.81); 6.8870 (0.42); 5.4083 (0.60); 5.3676 (0.59); 3.9371 (0.40); 3.9194 (4.52); 3.9097 (0.41); 3.8940 (0.42); 3.7173 (1.00); 3.5677 (16.00); 3.4097 (0.44); 3.3959 (0.35); 3.3885 (0.61); 3.3765 (0.33); 3.3667 (0.50); 3.3581 (0.37); 3.3460 (0.60); 3.3053 (68.51); 2.5088 (7.46); 2.5047 (13.11); 2.5003 (16.46); 2.4960 (11.44); 2.1853 4.25); 52.1338 (1.12); 2.1014 (0.35); 1.9869 (0.51); -0.0002 (0.44

Pr. I-22, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 11.2428 (1.19); 8.1534 (0.93); 8.0296 (1.22); 7.6219 (0.48); 7.5386 (0.32); 7.4271 (0.42); 7.4087 (0.34); 7.3973 (0.41); 7.1743 (0.51); 7.0232 (0.59); 6.8999 (0.55); 5.4085 (0.39); 5.3682 (0.40); 3.5678 (16.00); 3.4027 (0.33); 3.3829 (0.39); 3.3593 (0.39); 3.3396 (0.45); 3.3063 (44.54); 2.5091 (4.57); 2.5048 (8.08); 2.5004 (10.20); 2.4961 (7.06); 2.4919 (3.39

Pr. I-23, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.1280 (2.59); 8.0230 (5.52); 7.6822 (2.35); 7.6260 (0.77); 7.6205 (1.04); 7.6158 (0.81); 7.6102 (0.87); 7.6043 (1.32); 7.5994 (0.81); 7.4600 (0.58); 7.4410 (2.15); 7.4316 (1.79); 7.4254 (3.56); 7.4126 (0.45); 7.4088 (0.44); 7.3326 (2.45); 7.3272 (2.41); 7.1985 (1.71); 7.1779 (2.31); 7.0832 (1.69); 7.0777 (1.59); 7.0629 (1.20); 7.0573 (1.12); 5.8054 (0.89); 5.7845 (1.12); 5.7784 (1.08); 5.7573 (1.03); 5.7457 (5.02); 4.1720 (1.45); 41383 (1.51); 3.9380 (1.16); 3.9191 (16.00); 3.9111 (1.62); 3.9019 (0.56); 3.8949 (1.35); 3.8837 (0.61); 3.8677 (1.02); 3.7172 (1.13); 3.4113 (1.37); 3.3904 (1.50); 3.3679 (1.88); 3.3471 (3.07); 3.3181 (222.43); 3.2956 (2.50); 3.0392 (0.96); 3.0103 (1.76); 2.9811 (0.95); 2.5404 (0.55); 2.5058 (22.70); 2.5014 (28.23); 2.4973 (19.82); 2.1850 (15.42); 21552 (12,16); 2.1337 (1.25); 2.0937 (1.22); 2.0693 (1.60); 1.7192 (0.43); 1.7098 (0.51); 1.6879 (1.06); 1.6799 (1.16); 1.6576 (1.08); 1.6497 1.01); 1.6284 (0.42); 1.6183 (0.34); -0.0002 (3.59

Pr. I-24, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.2456 (1.52); 8.0300 (1.95); 7.6509 (0.77); 7.5729 (0.38); 7.5560 (0.48); 7.5073 (0.40); 7.4691 (0.39); 7.4483 (0.69); 7.4310 (1.15); 7.3068 (0.41); 7.1733 (0.95); 7.1587 (0.48); 7.0401 (0.47); 7.0226 (1.07); 6.8991 (1.02); 6.8867 (0.54); 5.7823 (0.36); 5.7753 (0.38); 5.4079 (0.75); 5.3668 (0.75); 4.1862 (0.53); 4.1685 (1.60); 4.1509 (1.64); 4.1333 (0.55); 3.9427 (0.50); 3.9151 (0.38); 3.8995 (0.42); 3.8721 (0.36); 3.5677 (16.00); 3.4143 (0.39); 3.3981 (0.72); 3.3863 (0.61); 3.3777 (0.79); 3.3705 (0.50); 3.3553 (0.89); 3.3345 (1.35); 3.3051 (157.96); 3.2815 (2.35); 2.5393 (0.49); 2.5088 (14.70); 2.5046 (26.37); 2.5002 (33.64); 2.4959 (23.56); 2.1003 (0.44); 2.0693 (0.40); 1.2645 (1.42); 1.2469 (2.97); 1.2400 0.72); 1.2293 (1.47); 1.2220 (0.79); -0.0002 (0.65

Pr. I-25, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 9.9614 (0.74); 8.0145 (2.40); 7.5928 (1.01); 7.5714 (1.17); 7.3208 (1.46); 7.3071 (0.70); 7.2994 (1.30); 7.1740 (1.03); 7.1591 (0.55); 7.0405 (0.52); 7.0230 (1.22); 6.8992 (1.11); 6.8872 (0.66); 5.6596 (0.40); 5.6551 (0.39); 5.6329 (0.33); 5.4091 (0.74); 5.3674 (0.79); 4.0567 (0.49); 4.0390 (1.48); 4.0212 (1.46); 4.0033 (0.53); 3.8597 (0.35); 3.8328 (0.42); 3.8169 (0.47); 3.7897 (0.39); 3.4163 (0.33); 3.3866 (0.68); 3.3795 (0.96); 3.3580 (1.24); 3.3017 (597.69); 3.2780 (9.69); 2.8438 (0.35); 2.6734 (0.79); 2.6688 (1.04); 2.6642 (0.78); 2.6596 (0.42); 2.5646 (0.57); 2.5389 (2.14); 2.5219 (5.06); 2.5086 (59.23); 2.5042 (109.71); 2.4997 (143.24); 2.4953 (100.83); 24909 (49.35); 24169 (0.34); 2.3310 (0.80); 2.3265 (1.05); 2.3219 (0.77); 2.3174 (0.44); 2.0845 (16.00); 2.0693 (0.71); 2.0492 (0.38); 2.0341 (5.45); 2.0091 (0.34); 1.9866 (6.39); 1.9074 (0.57); 1.2366 (0.62); 1.1926 (1.77); 1.1748 (3.51); 1.1570 1.74); 0.0079 (0.58); -0.0002 (11.65); -0.0084 (0.52

Pr. I-26, Solvent: dmeoo-ab, spectrometer: 601.6 MG 8.4672 (3.85); 8.0486 (5.34); 7.6970 (1.02); 7.6844 (1.12); 7.6825 (1.07); 7.4815 (0.39); 7.4787 (0.51); 7.4685 (1.41); 7.4657 (1.43); 7.4620 (0.89); 7.4599 (0.86); 7.4504 (1.06); 7.4483 (1.04); 74375 (0.46); 7.4353 (0.43); 7.4062 (0.68); 7.4033 (0.63); 7.3937 (0.89); 7.3912 (0.84); 7.3818 (0.49); 7.3790 (0.43); 7.2677 (0.66); 7.1791 (1.57); 7.1261 (0.77); 7.0907 (0.76); 7.0357 (1.98); 6.9453 (0.90); 6.9114 (1.77); 6b, 2149 (0.69); 6.2031 (0.76); 6.1965 (0.74); 6.1847 (0.68); 5.4492 (0.52); 5.4208 (1.19); 53714 (1.92); 5.3430 (0.57); 4.3799 (0.49); 4.3714 (1.02); 4.3630 (0.70); 4.3560 (0.40); 4.3340 (0.41); 4.0008 (0.69); 3.9822 (0.88); 3.9719 (1.21); 3.9505 (16.00); 3.8599 (0.63); 3.4498 (0.72); 3.4414 (0.72); 3.4382 (0.75); 3.4298 (0.73); 3.3934 (0.33); 3.3803 (0.47); 3.3741 (0.82); 3.3674 (0.80); 3.3513 (257.40); 3.277 (4.73); 3.2540 (0.54); 3.2352 (0.32); 3.2093 (0.78); 3.1975 (0.78); 3.1806 (0.75); 3.1687 (0.76); 2.8224 (0.48); 2.6152 (0.37); 2.5244 (0.70); 2.5214 (0.88); 2.5183 (0.85); 2.5094 (19.78); 2.5064 (43.07); 2.5034 (59.03); 2.5003 (43.14); 2.4973 (19.88); 2.3876 (0.37); 2.1158 (0.33); 2.0962 (0.40); 2.0768 (0.56); 2.0576 (0.37); 1.7993 (0.33); 1.7845 (0.32); 1.5558 (0.32); 1.0669 (1.56); 1.0553 (3.15); 1.0436 (1.54); -0.0002 (0.58

Pr. I-27, Solvent: dmeoo-ab, spectrometer: 399.95 MG 8.4585 (8.08); 8.0328 (10.28); 7.6974 (2.26); 7.6787 (2.63); 7.6756 (2.48); 7.4897 (1.02); 7.4855 (1.30); 7.4703 (3.14); 7.4662 (3.36); 7.4602 (1.96); 7.4567 (1.84); 7.4424 (2.63); 7.4391 (2.39); 7.4233 (1.37); 7.4197 (1.21); 7.4071 (1.81); 7.4025 (1.68); 7.3886 (2.13); 7.3843 (2.05); 7.3704 (0.98); 7.3663 (0.86); 7.3058 (1.79); 7.1725 (3.99); 7.1589 (2.01); 7.0392 (1.98); 7.0228 (4.48); 6.8996 (4.08); 6.8869 (2.30); 6.2216 (1.49); 6.2036 (1.77); 6.1940 (1.72); 6.1760 (1.51); 5.7471 (0.51); 5.4476 (0.75); 5.4055 (2.97); 5.3657 (3.05); 5.3235 (0.80); 4.3582 (0.92); 4.3242 (0.98); 4.2418 (2.43); 42242 (7.55); 4.2066 (7.72); 4.1890 (2.64); 4.0013 (1.61); 3.9735 (2.52); 3.9579 (2.32); 3.9431 (1.08); 3.9303 (2.05); 3.4108 (0.39); 3.4016 (0.71); 3.3920 (0.57); 3.3822 (0.92); 3.3730 (1.49); 3.3637 (1.00); 3.3533 (0.84); 3.3439 (1.20); 3.3106 (183.22); 3.2872 (2.66); 3.2609 (1.50); 3.2249 (2.44); 3.2068 (1.93); 3.1815 (1.76); 3.1636 (1.73); 2.8628 (0.64); 2.8332 (1.16); 2.8047 (0.66); 2.5405 (0.43); 2.5234 (1.07); 2.5102 (13.27); 2.5059 (24.52); 2.5014 (31.86); 2.4971 (22.64); 24927 (11.24); 2.1240 (0.85); 2.0914 (1.76); 2.0702 (0.74); 2.0559 (0.99); 1.9876 (0.37); 1.8426 (0.33); 1.8333 (0.39); 1.8112 (0.75); 1.8036 (0.80); 1.7607 (0.74); 1.7734 (0.70); 1.5986 (0.36); 1.57 71 (0.73); 1.5696 (0.77); 1.5474 (0.74); 1.5386 (0.71); 1.5184 (0.33); 1.3004 (7.76); 1.2933 (1.01); 1.2828 (16.00); 1.2652 (7.59); 1.2351 (0.34); -0.0002 1.60

Pr. I-28, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0171 (5.683); 7.4697 (0.60); 7.661 (0.56); 7.4621 (0.46); 7.4514 (1.65); 7.4464 (1.46); 7.4417 (1.21); 7, A335 (1.56); 7.4194 (3.55); 7.4160 (2.06); 7.4056 (2.67); 7.4003 (1.89); 7.3938 (0.93); 7.3836 (1.13); 7.3709 (0.33); 7.3047 (0.99); 7.1713 (2.25); 7.1577 (1.13); 7.0381 (1.11); 7.0216 (2.51); 6.8984 (2.24); 6.8857 (1.28); 5.9814 (0.88); 5.9614 (1.09); 5.9537 (1.04); 5.9337 (0.89); 5.7471 (6.72); 5.4476 (0.42); 5.4046 (1.66); 5.3655 (1.68); 5.3229 (0.44); 4.4020 (0.44); 4.3864 (1.15); 4.3708 (1.66); 4.3552 (1.64); 4.3397 (0.70); 4.3233 (0.60); 3.9771 (0.48); 3.9430 (0.53); 3.8949 (0.82); 3.8670 (0.94); 3.8513 (1.07); 3.8234 (0.91); 3.4077 (0.40); 3.3886 (0.50); 3.3794 (0.82); 3.3698 (0.55); 3.3600 (0.43); 3.3508 (0.62); 3.3407 (0.57); 3.3202 (2.60); 3.3037 (150.46); 3.2794 (2.65); 3.2573 (1.41); 3.2390 (0.53); 2.8733 (0.95); 2.8436 (0.64); 2.8154 (0.36); 2.5394 (0.49); 2.5091 (14.96); 2.5048 (27.61); 2.5003 (35.87); 2.4959 (25.26); 2.4915 (12.38); 2.2008 (16.00); 2.1528 (0.44); 21302 (0.51); 2.0953 (0.98); 2.0695 (0.48); 2.0599 (0.56); 1.8024 (0.44); 1.7783 (0.41); 1.5804 (0.41); 1.5731 (0.42); 1.5518 (0.40); 1.2632 7.28); 1.2476 (7.97); 1.2423 (7.88); 1.2267 (7.16); -0.0002 (2.89

Pr. I-29, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.4565 (1.73); 8.0315 (2.30); 8.0248 (0.51); 7.7954 (0.33); 7.5956 (0.48); 7.6772 (0.57); 7.6742 (0.54); 7.4671 (0.71); 7.4627 (0.80); 7.4587 (0.53); 7.4552 (0.44); 7.4412 (0.70); 7.4377 (0.58); 74217 (0.38); 7.4061 (0.46); 7.4011 (0.47); 7.3877 (0.47); 7.3828 (0.49); 6.4891 (1.30); 6.2006 (0.38); 6.1907 (0.36); 5.2931 (0.75); 5.2443 (0.76); 4.2400 (0.55); 42224 (1.69); 4.2048 (1.74); 4.1873 (0.58); 3.9986 (0.40); 3.9709 (0.53); 3.9553 (0.60); 3.9276 (0.40); 3.5676 (16.00); 3.3950 (0.41); 3.3670 (0.76); 3.3047 (263.69); 3.2210 (0.57); 3.2030 (0.44); 3.1774 (0.39); 3.1596 (0.37); 2.6736 (0.34); 2.6692 (0.46); 2.65644 (0.35); 2.5391 (0.83); 2.5222 (2.34); 2.5088 (25.92); 2.5045 (46.63); 2.5000 (60.82); 2.4956 (42.89); 2.4912 (20.95); 2.3267 (0.40); 2.2061 (4.83); 2.0923 (0.46); 1.9867 (0.51); 1.2987 (1.74); 1.2811 (3.61); 1.2635 (1.70); 1.2285 (0.36); 1.2108 (0.64); 1.1929 (0.43); -0.0002 (5.96

Pr. I-30, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0159 (1.28); 8.0108 (0.55); 7.4500 (0.38); 7.4451 (0.34); 7.4328 (0.36); 7.4187 (0.77); 7.4152 (0.45); 7.4050 (0.57); 7.3998 (0.45); 7.3834 (0.74); 6.4902 (0.89); 5.2938 (0.41); 5.2453 (0.54); 4.3853 (0.33); 4.3698 (0.47); 4.3541 (0.35); 3.5678 (16.00); 3.9827 (0.40); 3.3734 (0.54); 3.3640 (0.53); 3.3086 (171.11); 3, f, 2850 (2.02); 3.2756 (0.62); 2.5394 (0.42); 2.5092 (11.77); 2.5048 (21.39); 2.5004 (27.59); 2.4959 (19.13); 24915 (9,12); 2.2062 (3.37); 2.1998 (3.80); 2.1515 (1.30); 1.2623 (1.60); 1.2467 (1.71); 1.2415 (1.67); 1.2258 (1.55); 1.1435 (0.34); 1.1279 (0.40); 1.1145 (0.37); 1.1050 (0.57); 1.0893 0.52); -0.0002 (2.56

Pr. I-31, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0233 (1.02); 8.0197 (1.88); 7.4443 (0.76); 7.4391 (0.96); 7.4245 (0.87); 7.4209 (0.97); 7.164 (0.57); 7.4074 (0.75); 7.4009 (0.61); 7.3909 (1.29); 7.3847 (0.72); 7.3760 (0.33); 6.4905 (1.34); 5.9529 (0.34); 5.2966 (0.82); 5.2463 (0.77); 4.0391 (0.49); 4.0213 (0.50); 3.9372 (0.39); 3.9092 (0.51); 3.8974 (5.37); 3.8655 (0.34); 3.7074 (0.88); 3.5676 (16.00); 3.3764 (0.74); 3.3047 (286.21); 3.2618 (0.90); 3.2421 (0.56); 2.6736 (0.40); 2.6692 (0.50); 2.6646 (0.39); 2.5391 (0.93); 2.5220 (2.64); 2.5088 (28.26); 2.5045 (51.48); 2.5000 (66.48); 2.4956 (46.24); 2.4912 (22.09); 2.3314 (0.32); 2.3268 (0.42); 2.3221 (0.33); 2.2074 (5.61); 2.2024 (5.82); 2.1535 (2.41); 2.1061 (0.47); 2.0693 (0.33); 1.9867 (2.04); 1.3263 0.47); 1.1927 (0.57); 1.1749 (1.10); 1.1571 (0.53); 0.0079 (0.37); -0.0002 (6.91

Pr. I-32, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 16.2631 (0.38); 8.0318 (1.15); 8.0203 (5.20); 7.7557 (0.46); 7.7371 (0.89); 7.7009 (0.74); 7.6795 (1.24); 7.6650 (0.42); 7.6399 (0.53); 7.6207 (0.59); 7.6140 (0.52); 7.5938 (0.41); 7.5523 (1.22); 7.5459 (1.16); 7.5353 (0.60); 7.5299 (1.01); 7.5242 (0.85); 7.4447 (2.31); 7.4394 (2.84); 7.4313 (1.03); 7.4214 (2.77); 7.4170 (1.60); 7.4078 (1.83); 7.4011 (1.21); 7.3851 (0.76); 7.3763 (0.35); 7.3040 (0.81); 7.1709 (2.06); 7.1580 (1.04); 7.0378 (1.03); 7.0215 (2.23); 6.8976 (2.15); 6.8854 (1.91); 5.9724 (0.99); 5.9532 (0.93); 5.9449 (1.00); 5.9325 (0.39); 5.9246 (1.08); 5.7470 (1.85); 5.4484 (0.46); 5.4051 (1.45); 5.3643 (1.54); 5.3195 (0.58); 4.9609 (0.41); 4.8896 (0.38); 4.8202 (0.35); 4.7783 (0.37); 4.7678 (0.41); 4.7380 (0.45); 4.6844 (0.45); 4.6497 (0.42); 4.6007 (0.47); 4.5865 (0.42); 4.5744 (0.42); 4.5172 (0.39); 44274 (0.46); 4.3922 (0.47); 4.3645 (0.82); 4.3576 (0.85); 4.3288 (0.81); 4.2646 (0.53); 4.2390 (0.54); 4.2303 (0.53); 4.2099 (0.54); 4.1860 (0.49); 4.1531 (0.47); 4.1412 (0.51); 4.1323 (0.63); 4.1148 (0.53); 4.0977 (0.61); 4.0784 (0.65); 4.0545 (0.69); 4.0398 (0.70); 3.9951 (1.43); 3.9779 (1.89); 3.9602 (1.22); 3.9369 (1.61); 3.9089 (1.98); 3.8975 (16.00); 3.8689 (2.35); 3.8425 (5.42); 3.8277 (0.95); 3.8000 (0.79); 3.7951 (0.94); 3.7858 (0.98); 3.7576 (0.84); 3.7314 (0.87); 3.7163 (1.10); 3.6890 (1.02); 3.6729 (1.01); 3.6326 (1.17); 3.6052 (1.27); 3.5649 (1.52); 3.5501 (1.61); 3.5389 (1.70); 3.5053 (2.03); 3.4713 (2.35); 3.4295 (3.38); 3.3029 (6422.35); 3.2792 (69.07); 3.2425 (3.26); 3.1794 (0.53); 2.9376 (0.38); 2.9145 (0.40); 2.8906 (0.50); 2.8684 (0.77); 2.8385 (1.03); 2.8070 (0.86); 2.7784 (0.75); 2.7721 (0.73); 2.7320 (1.16); 2.6950 (2.49); 2.6777 (4.63); 2.6733 (7.84); 2.6689 (10.26); 2.6642 (7.69); 2.6598 (4.41); 2.65318 (2.17); 2.5389 (23.41); 2.5219 (52.93); 2.5086 (560.43); 2.5043 (102411); 2.4998 (19325.32); 2.4954 (922.95); 2.4909 (443.99); 2.3357 (3.13); 2.39310 (6.27); 2.3266 (8.54); 2.3220 (5.82); 2.2026 (14.50); 2.0990 (0.83); 2.0845 (1.06); 2.0692 (2.47); 2.0497 (0.51); 1.9860 (0.68); 1.9077 (0.59); 1.8810 (0.40); 1.8513 (0.36); 1.7997 (0.38); 1.7728 (0.71); 1.7479 (0.80); 1.7386 (0.66); 1.7219 (0.40); 1.5786 (0.62); 1.5528 (0.45); 1.4928 (0.36); 1.3984 (3.12); 1.2927 (0.49); 1.2362 (3.49); 1.1747 (0.48); 1.1140 (0.58); 1.1023 (1.00); 1.0846 (2.13); 1.0672 (1.07); 0.8903 (0.69); 0.8538 (0.43); 0.1461 (0.50); 0.0079 (4.72); -0.0002 (87.41); -0.0085 (3.62

Pr. I-33, Solvent: DMOSO-ab, spectrometer: 399.95 MHz 8.4566 (6.68); 8.1201 (3.35); 8.0259 (8.80); 7.6956 (1.82); 7.6766 (2.12); 7.6735 (2.06); 7.4844 (1.07); 7.4691 (2.57); 7.4649 (2.80); 7.4590 (1.62); 7.4554 (1.54); 7.4414 (2.15); 7.4378 (1.96); 7.4223 (1.12); 7, A185 (0.99); 7.4060 (1.49); 7.4015 (1.42); 7.3876 (1.76); 7.3831 (1.67); 7.3695 (0.81); 7.3650 (0.71); 7.3282 (3.13); 7.3227 (3.30); 7.1967 (2.18); 7.1758 (3.01); 7.0823 (2.30); 7.0765 (2.22); 7.0618 (1.65); 7.0562 (1.57); 6.2158 (1.25); 6.1978 (1.46); 6.1882 (1.42); 6.1702 (1.25); 4.2395 (2.06); 42219 (6.47); 4.2042 (6.57); 4.1866 (2.32); 4.1627 (1.82); 4.1291 (1.93); 3.9990 (1.32); 3.9712 (1.50); 3.9558 (1.63); 3.9279 (1.41); 3.5676 (0.85); 3.4783 (0.34); 3.4370 (0.46); 3.4137 (0.65); 3.3041 (1156.05); 3.2234 (1.98); 3.2053 (1.80); 3.1800 (1.59); 3.1622 (1.58); 3.0286 (1.28); 2.9990 (2.34); 2.9705 (1.32); 2.6953 (0.40); 2.6737 (1.46); 2.6690 (1.91); 2.6645 (1.44); 2.6599 (0.86); 2.5391 (4.19); 2.5221 (9.63); 2.5088 (106.69); 2.5044 (196.68); 2.4999 (256.40); 2.4955 (181.26); 2.4911 (89.11); 2.4232 (0.32); 2.3357 (0.73); 2.3313 (1.32); 2.3267 (1.75); 2.3221 (1.26); 2.3180 (0.66); 2.1506 (16.00); 2.0846 (1.51); 2.0693 (1.47); 2.0553 (1.72); 2.0495 (1.72); 1.9865 (0.36); 1.7046 (0.54); 1.6948 (0.65); 1.67391 (1.33); 1.6658 (1.46); 1.6433 (1.34); 1.6348 (1.25); 1.6134 (0.53); 1.6039 (0.45); 1.3983 (3.79); 1.3257 (0.55); 1.2977 (6.65); 1.2801 (193.76); 1.2713 (1.01); 1.2625 (6.43); 1.2363 (0.65); 0.0079 (1.10); -0.0002 21.35); -0.0085 (0.93

Pr. I-34, Solvent: DMOSO-ab, spectrometer: 601.6 MHz 8.4679 (3.81); 8.0482 (5.43); 7.6977 (1.01); 7.6958 (0.99); 7.6850 (1.12); 7.6830 (1.08); 7.4830 (0.44); 7.4804 (0.56); 7.4700 (1.38); 7.4674 (1.38); 7.4620 (0.83); 7.4599 (0.82); 7.4502 (1.06); 7.4482 (1.08); 7, A374 (0.49); 7.4351 (0.46); 7.4061 (0.69); 7.4032 (0.66); 7.3936 (0.95); 7.3910 (0.88); 7.3816 (0.51); 7.3789 (0.44); 6.5023 (2.36); 6.2168 (0.68); 6.2049 (0.74); 6.1983 (0.72); 6.1865 (0.67); 5.7613 (7.08); 5.3453 (0.54); 5.3169 (1.12); 5.2569 (1.34); 5.2286 (0.66); 4.3809 (0.39); 4.3587 (0.40); 4.0028 (0.65); 3.9842 (0.93); 3.9740 (1.09); 3.9514 (16.00); 3.8612 (0.70); 3.3944 (0.41); 3.3882 (0.70); 3.3632 (28.04); 3.2755 (0.33); 3.2556 (0.55); 3.2370 (0.933); 3.2108 (0.70); 3.1989 (0.71); 3.1820 (0.67); 3.1702 (0.68); 2.8232 (0.47); 2.5312 (1.27); 2.5112 (5.59); 2.5082 (12.27); 2.5052 (16.88); 2.5021 (12.39); 2.4991 (5.69); 2.2065 (8.65); 2.1944 (0.37); 2.1174 (0.33); 2.0963 (0.51); 2.0923 (0.54); 2.0650 (0.36); 1.8052 (0.33); -0.0002 (0.38

Pr. I-35, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 11.2422 (1.13); 8.0032 (0.63); 7.9957 (5.92); 7.4660 (0.78); 7.4610 (0.72); 7.4464 (1.45); 74411 (1.32); 7.4243 (0.75); 7.4188 (0.77); 7.4134 (1.32); 7.4029 (3.06); 7.4001 (3.16); 7.3958 (2.15); 7.3906 (2.48); 7.3883 (2.46); 7.3854 (2.16); 7.3808 (1.24); 7.3758 (0.48); 7.3689 (0.65); 7.3050 (1.04); 7.1716 (2.33); 7.1580 (1.17); 7.0383 (1.15); 7.0219 (2.61); 6.8987 (2.37); 6.8860 (1.33); 5.9368 (0.85); 5.9162 (1.05); 5.9092 (1.01); 5.8884 (0.86); 5.7470 (6.82); 5.4480 (0.45); 5.4056 (1.71); 5.3656 (1.76); 5.3229 (0.46); 4.3607 (0.54); 4.3276 (0.56); 3.9783 (0.52); 3.9451 (0.58); 3.8982 (0.86); 3.8704 (0.99); 3.8543 (1.10); 3.8266 (0.92); 3.4038 (0.47); 3.3942 (0.40); 3.3846 (0.60); 3.3753 (0.94); 3.3660 (0.68); 3.3552 (0.60); 3.3459 (0.82); 3.3035 (155.65); 3.2797 (3.08); 3.2542 (1.54); 3.2308 (1.36); 3.2104 (1.03); 2.8662 (0.37); 2.8372 (0.67); 2.8083 (0.37); 2.6691 (0.34); 2.6335 (1.00); 2.5392 (0.61); 2.5088 (19.47); 2.5045 (35.79); 2.5001 (46.44); 2.4956 (32.79); 2.4913 (16.12); 2.3269 (0.33); 2.1825 (16.00); 2.1289 (0.53); 2.0947 (1.03); 2.0694 (0.61); 2.0582 (0.57); 1.9868 (1.15); 1.8027 (0.48); 1.7797 (0.44); 1.5831 (0.43); 1.5750 (0.46); 1.5530 (0.44); 1.5437 (0.41); 1.1749 (0.63); -0.0002 (2.55

Pr. I-36, Solvent: dmeoo-ab, spectrometer: 601.6 MG 11.4895 (3.38); 10.1863 (3.70); 8.3910 (6.62); 8.1592 (3.53); 8.0430 (9.29); 8.0288 (0.55); 7.7244 (0.47); 7.7002 (1.67); 7.6979 (1.66); 7.6876 (1.92); 7.6852 (1.85); 7.4657 (1.17); 7.4636 (1.33); 7.4528 (2.04); 7.4507 (2.21); 7.4244 (0.92); 74221 (1.00); 7.4122 (1.90); 7.4098 (1.77); 7.3996 (1.17); 7.3971 (1.10); 7.3862 (1.34); 7.3837 (1.43); 7.3737 (1.75); 7.3713 (1.84); 7.3614 (0.76); 7.3591 (0.75); 7.3237 (3.21); 7.3200 (3.31); 7.1984 (2.31); 7.1845 (2.87); 7.0858 (2.25); 7.0820 (2.17); 7.0723 (1.81); 7.0685 (1.75); 6.1881 (1.17); 6.1758 (1.31); 6.1698 (1.27); 6.1574 (1.19); 5.7611 (0.34); 4.3791 (0.71); 4.3707 (1.48); 4.3622 (0.76); 4.1611 (1.55); 4.1391 (1.61); 3.9595 (1.23); 3.9410 (1.49); 3.9307 (1.62); 3.9123 (1.32); 3.4608 (0.38); 3.4524 (0.41); 3.4492 (1.10); 3.4408 (1.11); 3.4375 (1.19); 3.4291 (1.16); 3.4259 (0.53); 3.4175 (0.51); 3.3502 (2608.51); 3.3266 (44.53); 3.3163 (2.13); 3.3099 (1.28); 3.3036 (0.85); 3.2969 (0.92); 3.2906 (0.54); 3.2211 (1.52); 3.2088 (1.51); 3.1925 (1.46); 3.1802 (1.43); 3.0132 (1.04); 2.9931 (2.03); 2.9741 (1.09); 2.6208 (1.13); 2.6178 (2.52); 2.6148 (3.56); 2.6118 (2.54); 2.6087 (1.16); 2.5425 (1.61); 2.5241 (6.82); 2.5210 (8.57); 2.5179 (8.39); 2.5091 (185.56); 2.5061 (403.98); 2.5030 (555.96); 2.5000 (407.27); 24970 (188.25); 2.3933 (1.16); 2.3902 (2.55); 2.3872 (3.52); 2.3842 (2.53); 2.3812 (1.16); 2.1822 (0.35); 2.1494 (16.00); 2.1395 (0.55); 2.0765 (2.98); 2.0588 (1.44); 1.7651 (10.32); 1.7304 (10.25); 1.6828 (0.46); 1.6767 (0.53); 1.6622 (1.17); 1.6571 (1.32); 1.6421 (1.21); 1.6365 (1.14); 1.6222 (0.52); 1.6156 (0.39); 1.2341 (0.55); 1.1057 (0.37); 1.0664 (2.30); 1.0548 (4.51); 1.0431 (2.26); 0.8892 (1.02); 0.0052 (0.57); -0.0002 (19.53); -0.0058 (0.61

Pr. I-37, Solvent: dmeoo-ab, spectrometer: 601.6 MG 10.1802 (0.47); 8.4331 (4.31); 8.1681 (2.39); 8.0376 (6.11); 8.0301 (0.42); 8.0129 (0.66); 8.0063 (0.51); 7.9923 (0.53); 7.6964 (1.13); 7.6943 (1.13); 7.6837 (1.25); 7.6815 (1.19); 7.6108 (0.35); 7.5603 (0.40); 7.5470 (0.37); 7.4795 (0.67); 7.4774 (0.76); 7.4666 (1.46); 7.4644 (1.50); 7.4495 (0.81); 7.4474 (0.85); 7.4374 (1.22); 7.4353 (1.16); 7.4247 (0.69); 7.4223 (0.67); 7.4019 (0.85); 7.3993 (0.83); 7.3894 (1.16); 7.3870 (1.15); 7.3772 (0.59); 7.3747 (0.55); 7.3699 (0.39); 7.3686 (0.33); 7.35687 (0.89); 7.3552 (0.66); 7.3258 (2.46); 7.3221 (2.47); 7.1969 (1.65); 7.1832 (2.05); 7.0856 (1.54); 7.0819 (1.49); 7.0721 (1.23); 7.0684 (1.20); 6.2212 (0.77); 6.2096 (0.86); 6.2029 (0.81); 6.1912 (0.76); 5.7624 (9.49); 5.0743 (0.33); 4.4751 (0.41); 4.4647 (1.11); 4.4543 (1.51); 4.4439 (1.12); 4.4336 (0.43); 4.1638 (1.10); 4.1416 (1.14); 3.9864 (0.79); 3.9679 (0.94); 3.9576 (0.99); 3.9392 (0.84); 3.3595 (77.64); 3.3358 (1.15); 33207 (0.46); 3.3143 (0.75); 3.3081 (0.45); 3.2952 (0.40); 3.2163 (1.01); 3.2047 (1.01); 3.1875 (0.98); 3.1760 (1.00); 3.0158 (0.73); 2.9961 (1.34); 2.9770 (0.72); 2.9736 (0.64); 2.9289 (0.44); 2.5237 (0.36); 2.5207 (0.38); 2.5118 (6.66); 2.5088 (14.23); 2.5058 (19.48); 2.5028 (14.23); 2.4998 (6.54); 2.4358 (142); 2.1512 (10.79); 2.1417 (0.39); 2.0790 (0.91); 2.0734 (0.94); 2.0563 (0.97); 1.6628 (0.73); 1.6585 (0.78); 1.6409 (0.73); 1.6372 (0.71); 1.2834 (16.00); 1.2731 (15.86); 1.2189 (0.41); 1.2079 0.56); 1.1966 (0.41

Pr. I-38, Solvent: dmeoo-ab, spectrometer: 601.6 MG 11.5002 (0.44); 11.4938 (8.67); 10.1891 (2.60); 8.3915 (6.66); 8.0487 (9.69); 8.0344 (0.55); 7.7249 (0.48); 7.7007 (1.74); 7.6984 (1.70); 7.6881 (1.97); 7.6858 (1.89); 7.4652 (1.20); 7.4631 (1.33); 7.4523 (2.11); 7.4502 (2.21); 7.4248 (0.96); 7.4224 (1.03); 7.4126 (1.96); 7.4102 (1.79); 7.4000 (1.22); 7.3974 (1.11); 7.3868 (1.38); 7.3842 (1.43); 7.3743 (1.79); 7.3719 (1.87); 7.3620 (0.82); 7.3596 (0.76); 6.5019 (4.31); 6.1914 (1.21); 6.1792 (1.34); 6.1731 (1.29); 6.1608 (1.21); 5.7607 (9.61); 5.3439 (0.90); 5.3160 (1.89); 5.2555 (2.45); 52272 (1.22); 4.3780 (0.69); 4.3555 (0.71); 3.9745 (0.69); 3.9603 (1.30); 3.9514 (0.76); 3.9421 (1.33); 3.9317 (1.26); 3.9132 (1.09); 3.3947 (0.49); 3.3888 (0.81); 3.3814 (0.93); 3.3746 (1.97); 3.3590 (478.95); 3.3355 (6.42); 3.2777 (0.47); 3.2741 (0.54); 3.2543 (0.95); 3.2350 (0.55); 32317 (0.51); 3.2193 (1.24); 3.2071 (1.16); 3.1906 (1.09); 3.1784 (1.10); 2.8441 (0.46); 2.8230 (0.89); 2.8032 (0.47); 2.6189 (0.38); 2.6158 (0.53); 2.6128 (0.37); 2.5251 (1.07); 2.5221 (1.35); 2.5189 (1.34); 2.5101 (27.40); 2.5071 (59.81); 2.5041 (82.19); 2.5010 (60.15); 2.4980 (27.59); 2.3913 (0.36); 2.3882 (0.51); 2.3852 (0.36); 2.2044 (16.00); 2.1935 (0.67); 2.1176 (0.60); 2.0944 (0.99); 2.0767 (1.05); 2.0643 (0.66); 1.8125 (0.56); 1.8064 (0.63); 1.7918 (0.60); 1.7862 (0.55); 1.7658 (6.60); 1.7312 (6.40); 1.5601 (0.58); 1.5536 (0.61); 1.5398 (0.60); 1.5335 (0.55); -0.0002 (2.78

Pr. I-39, Solvent: dmeoo-ab, spectrometer: 601.6 MG 8.4330 (3.80); 8.0442 (5.68); 8.0358 (0.39); 7.6970 (1.02); 7.6950 (1.05); 7.6843 (1.11); 7.6822 (1.10); 7.4760 (0.55); 7.4735 (0.63); 7.4630 (1.31); 7.4606 (1.35); 7.4490 (0.73); 7.4468 (0.78); 7.4370 (1.08); 7.4348 (1.04); 7.4242 (0.59); 74218 (0.61); 7.4018 (0.81); 7.3992 (0.78); 7.3894 (0.99); 7.3868 (0.99); 7.3772 (0.48); 7.3746 (0.45); 6.5014 (2.50); 6.2227 (0.68); 6.2112 (0.74); 6.2044 (0.72); 6.1927 (0.68); 5.7626 (7.28); 5.3427 (0.48); 53151 (1.01); 5.2570 (1.39); 52286 (0.68); 4.4753 (0.37); 4.4649 (1.02); 4.4545 (1.42); 4.4442 (1.05); 4.4338 (0.40); 4.3753 (0.41); 4.3543 (0.47); 3.9850 (0.67); 3.9740 (0.39); 3.9667 (0.90); 3.9563 (1.02); 3.9380 (0.68); 3.3871 (0.38); 3.3806 (0.33); 3.3741 (0.59); 3.3677 (1.13); 3.3512 (16.50); 3.2753 (0.34); 3.2562 (0.57); 3.2368 (0.33); 3.2130 (0.71); 3.2014 (0.72); 3.1843 (0.68); 3.1727 (0.69); 2.8253 (0.48); 2.5248 (1.14); 2.5226 (0.38); 2.5105 (7.25); 2.5075 (16.45); 2.5044 (23.03); 2.5014 (17.00); 2.4983 (7.85); 2.2054 (9.16); 2.2048 (9.10); 2.1937 (0.42); 21147 (0.34); 2.0951 (0.49); 2.0893 (0.54); 2.0781 (0.53); 2.0612 (0.38); 1.8017 (0.32); 1.2844 (15.64); 1.2740 (16.00); 1.2216 (0.41); 1.2112 (0.61); -0.0002 (0.82

Pr. I-40, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 11.2422 (5.94); 7.9949 (5.72); 7.4653 (0.77); 7.4605 (0.71); 7.4459 (1.43); 7.4404 (1.28); 7.4238 (0.77); 7.4183 (0.74); 7.4129 (1.31); 7.4024 (3.04); 7.3996 (3.11); 7.3953 (2.07); 7.3902 (2.42); 7.3876 (2.40); 7.3849 (2.12); 7.3680 (0.73); 6.4905 (2.83); 5.9357 (0.83); 5.9151 (1.03); 5.9080 (0.98); 5.8874 (0.84); 5.7469 (2.28); 5.3377 (0.47); 5.2953 (1.66); 5.2482 (1.70); 5.2052 (0.48); 4.3818 (0.50); 4.3504 (0.55); 4.2332 (0.34); 4.2239 (0.33); 4.0085 (0.47); 3.9939 (0.73); 3.9858 (0.52); 3.9511 (0.56); 3.8979 (0.66); 3.8700 (0.99); 3.8540 (1.08); 3.8262 (0.92); 3.5677 (0.53); 3.4290 (0.35); 3.4160 (0.43); 3.3987 (0.63); 3.3894 (0.56); 3.3797 (0.79); 3.3703 (1.18); 3.3602 (0.98); 3.3405 (1.57); 3.3057 (233.47); 32740 (2.01); 3.2536 (1.52); 3.2301 (1.34); 3.2097 (1.03); 2.8645 (0.36); 2.8359 (0.65); 2.8068 (0.36); 2.6738 (0.36); 2.6693 (0.46); 2.6648 (0.34); 2.5392 (0.93); 2.5090 (26.36); 2.5046 (47.75); 2.5002 (61.37); 2.4958 (42.47); 2.4914 (20.29); 2.3317 (0.32); 2.3268 (0.42); 2.3019 (0.34); 2.2074 (10.77); 2.1818 (16.00); 2.1271 (0.55); 2.0981 (1.03); 2.0693 (0.80); 1.9868 (0.59); 1.8053 (0.44); 1.7848 (0.41); 1.5798 (0.41); 1.5723 (0.44); 1.5509 (0.42); 1.5421 (0.39); 1.3563 (0.52); 1.1749 (0.34); 0.0080 0.74); -0.0002 (13.98); -0.0085 (0.54

Pr. I-41, Solvent: DMOSO-ab, spectrometer: 601.6 MHz 10.1798 (0.42); 8.4688 (4.33); 8.1697 (2.30); 8.0425 (5.44); 8.0125 (0.52); 7.6976 (1.19); 7.6962 (1.20); 7.6850 (1.91); 7.6833 (1.28); 7.4851 (0.58); 7.4828 (0.68); 7.4721 (1.58); 7.4699 (1.57); 7.4617 (0.94); 7.4597 (0.93); 7.4498 (1.30); 7.4479 (1.27); 7.4370 (0.58); 7.4348 (0.55); 7.4054 (0.79); 7.4027 (0.77); 7.3930 (1.19); 7.3905 (1.09); 7.3808 (0.58); 7.3782 (0.51); 7.3271 (2.14); 7.3234 (2.25); 7.1969 (1.61); 7.1833 (2.02); 7.0856 (1.48); 7.0819 (1.46); 7.0721 (1.20); 7.0684 (1.17); 6.2154 (0.79); 6.2035 (0.89); 6.1970 (0.85); 6.1851 (0.79); 5.7623 (10.04); 4.1673 (1.10); 4.1450 (1.15); 4.0032 (0.81); 3.9847 (0.96); 3.9744 (1.01); 3.9515 (16.00); 3.9332 (0.41); 3.8606 (0.74); 3.3571 (43.62); 3.3411 (0.54); 3.3341 (1.03); 3.3215 (0.51); 3.3152 (0.79); 3.3089 (0.48); 3.3027 (0.33); 3.2960 (0.43); 3.2137 (0.97); 3.2018 (0.96); 3.1850 (0.95); 3.1731 (0.93); 3.0139 (0.73); 2.9941 (1.37); 2.9749 (0.71); 2.9719 (0.67); 2.5111 (6.14); 2.5082 (13.10); 2.5051 (17.92); 2.5021 (13.27); 2.4992 (6.30); 2.1520 (10.24); 2.0787 (0.97); 2.0763 (0.92); 2.0594 (0.99); 1.6788 (0.34); 1.6646 (0.79); 1.6588 (0.86); 1.6444 (0.81); 1.6385 (0.78); -0.0002 (0.680

Pr. I-42, Solvent: DMOSO-ab, spectrometer: 399.95 MHz 8.4270 (4.07); 8.0307 (5.55); 8.0221 (0.45); 7.6958 (1.12); 7.6772 (1.33); 7.6737 (1.22); 7.4839 (0.57); 7.4798 (0.69); 7.4647 (1.56); 7.4607 (1.65); 7.4533 (0.91); 7.4498 (0.91); 7.4356 (1.38); 7.4321 (1.23); 7, A166 (0.81); 7.4127 (0.67); 7.4047 (0.98); 7.4003 (0.96); 7.3864 (1.12); 7.3820 (1.08); 7.3684 (0.48); 7.3640 (0.44); 7.3034 (0.96); 71701 (2.17); 7.1572 (1.11); 7.0368 (1.08); 7.0211 (2.45); 6.8972 (2.18); 6.8852 (1.25); 6.2237 (0.75); 6.2060 (0.88); 6.1962 (0.86); 6.1,784 (0.77); 5.4442 (0.39); 5.4023 (1.59); 5.3636 (1.61); 5.3212 (0.42); 44835 (0.41); 4.4680 (1.07); 4.4524 (1.46); 4.4367 (1.07); 4.4212 (0.44); 4.3538 (0.54); 4.3210 (0.55); 3.9922 (0.87); 3.9645 (1.20); 3.9488 (1.32); 3.9212 (0.92); 3.4502 (0.44); 3.4326 (0.46); 3.4152 (0.33); 3.4008 (0.51); 3.3910 (0.45); 3.3808 (0.67); 3.93722 (1.02); 3.3624 (0.84); 3.3519 (0.87); 3.3043 (166.52); 3.2620 (1.15); 3.2243 (1.34); 3.2063 (1.03); 3.1809 (0.93); 3.1631 (0.91); 2.8633 (0.34); 2.8346 (0.62); 2.8051 (0.36); 2.6737 (0.37); 2.6691 (0.50); 2.6645 (0.39); 2.5620 (0.34); 2.5482 (0.60); 2.5392 (0.91); 2.5222 (2.55); 2.5090 (29.79); 2.5046 (54.44); 2.5001 (70.33); 2, A957 (48,78); 2.4912 (23.43); 2.3314 (0.37); 2.3269 (0.48); 2.3220 (0.35); 21228 (0.46); 2.0885 (0.95); 2.0696 (0.57); 2.0562 (0.53); 1.8066 (0.40); 1.8012 (0.42); 1.7769 (0.38); 1.5660 (0.40); 1.5452 (0.98); 1.5369 (0.37); 1.3982 (2.06); 1.2865 (16.00); 1.2709 (15.83); 1.2231 (0.44); 1.2121 (0.43); 1.2077 (0.45); 1.1969 (0.37); 1.0741 (0.41); 1.0566 (0.82); 1.0392 (0.42); 0.0593 (3.79); 0.0080 (0.35); -0.0002 (6.93

Pr. I-43, Solvent: DMSOSO-ab, spectrometer: 399.95 MHz 7.9999 (5.44); 7.6817 (1.26); 7.6774 (1.33); 7.6622 (1.49); 7.6579 (1.44); 7.5743 (1.38); 7.5718 (1.33); 7.5536 (1.91); 7.5514 (1.80); 7.4586 (0.70); 7.4541 (0.72); 7.4399 (1.25); 7.4356 (1.20); 7.4197 (0.86); 7, A153 (0.76); 7.3715 (1.06); 7.3689 (1.03); 7.3524 (1.53); 7.3337 (0.68); 7.3110 (1.00); 7.1780 (2.27); 7.1692 (1.14); 7.0447 (1.12); 7.0331 (2.47); 6.9091 (2.41); 6.8974 (1.29); 5.7586 (1.36); 5.4570 (0.58); 5.4146 (1.93); 5.93727 (1.88); 5.3304 (0.61); 4.3579 (0.57); 4.3259 (0.60); 3.9761 (0.55); 3.9431 (0.60); 3.7316 (1.47); 3.7147 (0.56); 3.7106 (0.45); 3.7028 (0.82); 3.6881 (2.43); 3.6797 (0.91); 3.6697 (0.48); 3.6657 (0.60); 3.6619 (0.32); 3.6547 (0.35); 3.6499 (0.38); 3.6366 (16.00); 3.5988 (2.41); 3.5553 (1.41); 3.5094 (0.37); 3.4959 (0.55); 3.4838 (0.44); 3.4722 (0.73); 3.4608 (0.63); 3.4013 (0.50); 3.3731 (1.42); 3.3365 (188.87); 3.3330 (208.54); 3.2881 (0.67); 3.2577 (0.90); 3.2290 (0.43); 2.8574 (0.40); 2.8302 (0.72); 2.8000 (0.42); 2.6758 (0.58); 2.6714 (0.80); 2.6667 (0.57); 2.5413 (0.55); 2.5066 (90.94); 2.5022 (116.93); 2.4978 (85.12); 2.3330 (0.60); 2.3289 (0.79); 2.3246 (0.56); 2.1169 (0.57); 2.0860 (1.08); 2.0516 (0.59); 1.9892 (0.47); 1.7965 (0.47); 1.7900 (0.50); 1.7605 (0.47); 1.7257 (10.35); 1.5959 (0.35); 1.5614 (0.51); 1.5351 (0.43); 1.3974 (10.30); 0.0079 (2.54); -0.0002 (65.29); - 0.0084 (2.57

Pr. I-44, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 7.9973 (5.62); 7.6812 (1.27); 7.6768 (1.36); 7.6617 (1.51); 7.6573 (1.52); 7.5740 (1.31); 7.5715 (1.37); 7.5535 (1.83); 7.5510 (1.80); 7.4582 (0.72); 7.4538 (0.77); 7.4396 (1.25); 7.4354 (1.23); 7.4194 (0.87); 7, A149 (0.81); 7.3711 (1.06); 7.3683 (1.09); 7.3519 (1.48); 7.3494 (1.50); 7.3333 (0.66); 7.3304 (0.66); 7.0017 (1.03); 6.8646 (2.44); 6.7275 (1.16); 6.2958 (2.65); 5.7584 (0.72); 5.2581 (0.57); 5.2156 (1.88); 5.1710 (1.85); 5.1286 (0.60); 4.3802 (0.53); 4.3475 (0.55); 4.0010 (0.51); 3.9657 (0.56); 3.7313 (1.38); 3.7051 (0.44); 3.6878 (2.41); 3.6368 (16.00); 3.5985 (2.44); 3.5549 (1.45); 3.3940 (0.41); 3.3749 (0.60); 3.3653 (1.04); 3.3375 (113.54); 3.3330 (120.36); 3.3097 (1.91); 3.2817 (0.57); 3.2511 (0.79); 3.2217 (0.45); 2.8487 (0.45); 2.8190 (0.69); 2.7906 (0.39); 2.6758 (0.33); 2.6714 (0.47); 2.6668 (0.35); 2.5245 (1.25); 2.5111 (25.57); 2.5068 (51.71); 2.5023 (68.39); 2.4978 (50.35); 2.4935 (24.92); 2.3336 (0.97); 2.3290 (0.48); 2.3246 (0.35); 2.1846 (11.44); 2.1649 (0.36); 2.1150 (0.53); 2.0844 (1.06); 2.0526 (0.59); 1.7764 (0.45); 1.7690 (0.50); 1.7252 (10.43); 1.5473 (0.47); 1.5236 (0.43); 1.3973 11.60); 0.0080 (1.08); -0.0002 (32.46); -0.0085 (1.30

Pr. I-45, Solvent: СсОоЗсМ, spectrometer: 399.95 MHz 7.6947 (4.34); 7.4491 (0.84); 7.4305 (0.92); 7.4254 (0.84); 7.3320 (0.44); 7.3258 (0.63); 7.3203 (0.72); 7.3162 (0.54); 7.3102 (1.72); 7.3067 (2.16); 7.3025 (1.41); 7.2947 (1.83); 7.2934 (1.90); 7.2883 (1.68); 7.2833 (0.55); 7.2771 (0.45); 7.2719 (0.60); 6.3908 (2.22); 6.1120 (0.79); 6.0903 (0.92); 6.0843 (0.90); 6.0627 (0.82); 5.1256 (0.46); 5.0837 (2.13); 5.05391 (2.12); 5.0111 (0.43); 4.4972 (0.43); 4.4638 (0.46); 4.0672 (0.47); 4.0493 (0.49); 3.9814 (0.96); 3.9536 (1.26); 3.9384 (2.44); 3.9105 (1.93); 3.9060 (2.94); 3.8638 (2.52); 3.8315 (1.07); 3.5207 (1.82); 3.5046 (4.09); 3.4884 (2.25); 3.367 (0.39); 3.3478 (0.51); 3.3420 (1.43); 3.3288 (0.51); 3.3204 (1.44); 3.3098 (0.84); 3.2992 (1.25); 3.2799 (16.00); 3.2516 (0.97); 3.2452 (0.35); 2.8737 (0.34); 2.8428 (0.59); 2.8163 (0.33); 2.8102 (0.33); 2.6725 (2.48); 2.6564 (4.70); 2.6401 (2.18); 2.2249 (9.95); 2.2238 (9.99); 22112 (0.56); 2.2042 (0.44); 2.1611 (0.68); 2.1428 (6.26); 2.1197 (0.50); 2.1136 (0.43); 1.9718 (2.14); 1.9641 (0.42); 1.9579 (0.50); 1.9522 (3.73); 1.9460 (6.95); 1.9399 (9.67); 1.9337 (6.66); 1.9275 (3.44); 1.8713 (0.40); 1.8612 (0.42); 1.8399 (0.38); 1.8303 (0.38); 1.7047 (0.41); 1.6946 (0.43); 1.6730 (0.39); 1.6630 (0.38); 1.4352 (0.38); 1.2211 (0.58); 1.2033 1.16); 1.1854 (0.58); -0.0002 (7.39

Pr. I-46, Solvent: СсОоЗсМ, spectrometer: 399.95 MHz 7.7098 (16.00); 7.6988 (0.62); 7.6360 (0.932); 7.5050 (3.34); 7.4973 (1.00); 7.4870 (4.53); 7.4826 (3.75); 7.4318 (2.04); 7.4279 (2.31); 7.4139 (5.47); 7.4108 (5.37); 7.3990 (5.47); 7.3953 (7.20); 7.3695 (4.16); 7.3659 (4.15); 7.3519 (3.39); 7.3503 (3.40); 7.3328 (1.41); 7.3296 (1.28); 6.5749 (0.38); 6.4214 (8.69); 6.0495 (2.93); 6.0283 (3.39); 6.0217 (3.32); 6.0006 (3.02); 5.1555 (1.81); 5.1136 (8.30); 5.0840 (8.28); 5.0627 (0.56); 5.0419 (1.64); 4.7535 (0.36); 4.7404 (4.62); 4.7119 (8.51); 4.6494 (8.84); 4.6209 (4.79); 4.5236 (1.70); 4.4904 (1.83); 4.2998 (1.04); 4.2970 (1.10); 4.2944 (1.05); 4.2789 (0.52); 4.2729 (0.81); 4.2669 (0.57); 4.2329 (10.96); 4.2295 (12.67); 42271 (12.56); 4.2236 (10.69); 4.2072 (0.42); 42022 (0.49); 4.1966 (0.34); 4.1894 (1.01); 4.1835 (1.04); 4.1477 (0.65); 4.1147 (2.01); 4.0969 (5.88); 4.0791 (6.37); 4.0713 (1.49); 4.0613 (2.08); 4.0205 (1.91); 4.0151 (1.21); 3.9758 (1.66); 3.9569 (4.13); 3.9420 (1.96); 3.9292 (4.45); 3.9138 (4.38); 3.8860 (4.04); 3.4075 (0.75); 3.3980 (1.48); 3.3884 (0.96); 3.3789 (1.66); 3.3694 (3.04); 3.3598 (1.79); 3.3494 (2.05); 3.3410 (2.91); 3.3313 (1.17); 3.31 75 (6.00); 3.2965 (4.59); 3.2829 (1.89); 3.2745 (4.87); 3.2534 (3.85); 2.9136 (1.22); 2.9069 (1.30); 2.8763 (2.28); 2.8500 (1.34); 2.8435 (1.24); 2.8056 (4.86); 2.7997 (9.26); 2.7937 (4.51); 2.7616 (0.40); 2.5744 (0.78); 2.5663 (0.81); 2.5636 (0.80); 2.5551 (1.01); 2.5523 (0.88); 2.3853 (1.22); 2.3744 (1.04); 2.3634 (1.01); 2.3482 (0.38); 2.2546 (40.35); 22101 (635.56); 2.1498 (2.65); 2.1438 (2.45); 2.1376 (1.97); 2.1314 (1.25); 21252 (0.86); 2.1163 (0.65); 2.0911 (0.78); 2.0751 (0.49); 2.0239 (0.99); 2.0016 (27.26); 1.9944 (5.34); 1.9824 (50.27); 1.9763 (87.51); 1.9701 (119.94); 1.9639 (81.78); 1.9577 (41.88); 1.9323 (1.22); 1.9216 (1.14); 1.9018 (1.81); 1.8919 (1.88); 1.8699 (1.68); 1.8604 (1.68); 1.8389 (0.90); 1.8299 (0.80); 1.8109 (0.58); 1.8047 (0.78); 1.7985 (0.99); 1.7924 (0.78); 1.7862 (0.56); 1.7670 (0.88); 1.7563 (0.98); 1.7366 (1.75); 1.7263 (1.80); 1.7049 (1.68); 1.6950 (1.63); 1.6751 (0.82); 1.6647 (0.76); 1.4653 (1.91); 1.2985 (1.33); 1.2506 (7.19); 1.2327 (14.14); 1.2149 (7.00); 1.1607 (0.49); 1.1432 0.81); 1.1256 (0.49); 1.0727 (0.33); 0.8679 (0.42); 0.8496 (0.75); 0.8311 (0.35

Pr. I-47, Solvent: СсОоЗсМ, spectrometer: 399.95 MHz 7.1218 (10.43); 7.5170 (1.70); 7.5135 (1.70); 7.4974 (2.88); 7.4579 (1.65); 7.4548 (1.86); 7.4484 (1.41); 7.4369 (3.55); 7.4295 (3.37); 7.4255 (1.91); 7.4109 (1.81); 7.4068 (1.18); 7.3942 (2.42); 7.3903 (2.40); 7.3758 (2.15); 7.3721 (2.26); 7.3574 (0.84); 7.3538 (0.80); 6.4214 (5.29); 6.0171 (1.83); 5.9960 (2.08); 5.9893 (2.09); 5.9682 (1.90); 5.1964 (16.00); 5.1556 (1.09); 5.1138 (5.01); 5.0843 (4.97); 5.0630 (0.42); 5.0423 (0.98); 4.5208 (1.03); 4.4877 (1.10); 4.1142 (1.53); 4.0963 (4.62); 4.0785 (4.67); 4.0607 (1.58); 3.9764 (1.02); 3.9579 (2.56); 3.9414 (1.19); 3.9300 (2.88); 3.9150 (2.78); 3.8871 (2.58); 3.4084 (0.43); 3.3988 (0.89); 3.3892 (0.58); 3.3797 (1.03); 3.3697 (2.33); 3.3662 (3.38); 3.3608 (1.33); 3.3451 (3.67); 3.3318 (0.77); 3.3232 (2.75); 3.3184 (1.37); 3.3113 (1.60); 3.3023 (2.81); 3.2835 (0.82); 32769 (0.77); 2.9153 (0.69); 2.9084 (0.77); 2.8774 (1.36); 2.8515 (0.79); 2.8447 (0.74); 2.2543 (30.24); 2.2363 (269.20); 22031 (2.30); 2.1993 (2.26); 2.1948 (2.21); 2.1497 (1.32); 2.1436 (1.13); 2.1373 (0.78); 2.1311 (0.43); 2.0813 (34.57); 2.0012 (20.87); 1.9941 (2.35); 1.9877 (2.05); 1.9821 (17.18); 1.9760 (32.55); 1.9698 (45.34); 1.9636 (31.03); 1.9574 (16.06); 1.9318 (0.55); 1.9213 (0.56); 1.9020 (0.98); 1.8922 (1.02); 1.8699 (0.91); 1.8613 (0.91); 1.8382 (0.42); 1.8302 (0.39); 1.7982 (0.33); 1.7671 (0.44); 1.7563 (0.51); 1.7366 (0.96); 1.7266 (1.03); 1.7049 (0.92); 1.6951 (0.92); 1.6753 (0.42); 1.6647 (0.39); 1.367 7 (0.37); 1.2970 (0.36); 1.2497 (5.85); 1.2319 (11.61); 1.2140 (5.73

Pr. I-48, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.7902 (0.68); 7.9970 (5.19); 7.9761 (5.91); 7.9547 (0.72); 7.9315 (9.00); 7.6490 (1.92); 7.6440 (2.23); 7.6284 (1.69); 7.6246 (2.39); 7.5485 (4.53); 7.5283 (4.15); 7.4146 (0.72); 7.4100 (0.72); 7.3951 (1.97); 7.3878 (1.07); 7.3761 (2.01); 7.3714 (1.84); 7.3456 (1.31); 7.3422 (2.09); 7.3245 (5.85); 7.3075 (3.23); 7.3040 (2.68); 7.1774 (3.50); 7.1653 (1.75); 7.0442 (1.77); 7.0290 (3.38); 6.9103 (4.27); 6.8931 (1.68); 5.7570 (1.48); 5.4653 (0.86); 5.4222 (2.79); 5.3799 (2.90); 5.3374 (0.95); 4.9351 (0.36); 4.9292 (0.38); 4.3771 (0.82); 4.3438 (0.94); 4.0377 (1.00); 4.0199 (1.05); 4.0020 (0.66); 3.9896 (0.79); 3.9557 (0.89); 3.7260 (0.37); 3.7192 (0.42); 3.7149 (0.90); 3.7108 (0.68); 3.7029 (1.01); 3.7008 (1.11); 3.6802 (1.10); 3.6782 (1.02); 3.6703 (0.70); 3.6661 (0.90); 3.6619 (0.43); 3.6550 (0.39); 3.6506 (0.32); 3.5892 (0.33); 3.5810 (0.34); 3.5681 (1.60); 3.5249 (0.41); 3.4860 (6.13); 3.4736 (1.57); 3.4612 (1.26); 3.4501 (0.69); 3.4450 (0.67); 3.4201 (1.03); 3.4114 (1.62); 3.9520 (1310.13); 3.2874 (1.52); 3.2724 (1.90); 3.2441 (1.07); 2.8730 (0.66); 2.8456 (1.15); 2.8153 (0.73); 2.6770 (1.19); 2.6725 (1.63); 2.6679 (1.19); 2.6634 (0.58); 2.5425 (0.99); 2.5395 (1.02); 2.5258 (5.86); 2.5211 (8.60); 2.5124 (91.05); 2.5080 (183.71); 2.5034 (239.69); 2.4989 (172.45); 2.4944 (82.97); 2.4365 (16.00); 2.3392 (0.62); 2.3346 (1.23); 2.3301 (1.66); 2.3256 (1.23); 2.1330 (0.87); 2.0985 (1.69); 2.0748 (5.93); 1.9894 (4.40); 1.9097 (0.58); 1.8394 (0.58); 1.8270 (0.41); 1.7990 (0.85); 1.7767 (0.80); 1.7681 (0.75); 1.7468 (0.38); 1.6999 (1.24); 1.6301 (13.53); 1.5791 (0.78); 1.5713 (0.79); 1.5491 (0.77); 1.5413 (0.72); 1.5156 (0.44); 1.3972 0.81); 1.2346 (1.08); 1.1925 (1.21); 1.1747 (2.40); 1.1569 (1.18); 0.8894 (0.34); -0.0002 (0.54

Pr. I-49, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 7.8972 (4.77); 7.9763 (5.33); 7.9518 (0.62); 7.9287 (8.52); 7.6480 (1.25); 7.6430 (2.05); 7.6273 (1.64); 7.6236 (2.14); 7.5485 (4.20); 7.5284 (3.81); 7.4143 (0.63); 7.4098 (0.64); 7.3947 (1.76); 7.3877 (1.02); 7.3759 (1.77); 7.3712 (1.61); 7.3417 (1.89); 7.3243 (5.05); 7.3071 (2.47); 7.3038 (2.34); 6.9969 (1.33); 6.8598 (2.95); 6.7228 (1.41); 6.2961 (4.12); 5.2649 (0.80); 52221 (2.59); 5.1775 (2.59); 5.1344 (0.83); 4.9345 (0.37); 4.9288 (0.38); 4.3970 (0.77); 4.3648 (0.84); 4.0376 (0.75); 4.0197 (1.23); 4.0020 (0.68); 3.9811 (0.83); 3.5680 (0.83); 3.5243 (0.39); 3.4842 (5.65); 3.4402 (0.89); 3.3511 (2030.22); 3.2668 (1.93); 3.2363 (1.23); 3.1746 (0.41); 3.1616 (0.37); 2.8637 (0.60); 2.8353 (1.09); 2.8060 (0.69); 2.6767 (1.75); 2.6722 (2.40); 2.6677 (1.77); 2.5423 (1.64); 2.5393 (1.69); 2.5256 (9.33); 2.5209 (13.77); 2.5120 (139.02); 2.5077 (275.18); 2.5032 (354.87); 2.4986 (256.90); 2.4943 (125.30); 24372 (14.65); 2.3344 (1.81); 2.3299 (2.42); 2.3253 (1.79); 2.1821 (16.00); 2.1249 (0.81); 2.0980 (1.59); 2.0747 (5.10); 1.9893 (3.14); 1.8382 (0.33); 1.8062 (0.37); 1.7863 (0.72); 1.7783 (0.74); 1.7549 (0.72); 1.7260 (0.933); 1.6990 (1.09); 1.6285 (11.23); 1.6003 (0.939); 1.5910 (0.43); 1.5688 (0.67); 1.5602 (0.73); 1.5392 (0.71); 1.5295 (0.68); 1.5114 (0.41); 1.2343 (1.34); 1.1923 (0.89); 1.1746 (1.71); 1.1567 (0.86); 0.8893 (0.40); -0.0002 (0.90

Pr. I-50, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0507 (5.75); 7.6724 (0.48); 7.6592 (0.52); 7.6502 (0.92); 7.6369 (0.93); 7.6278 (0.59); 7.6144 (0.50); 7.3142 (1.67); 7.2899 (1.20); 7.2864 (1.22); 7.2665 (0.63); 7.2625 (0.62); 7.1810 (2.39); 7.1677 (1.15); 7.0478 (1.17); 7.0317 (2.61); 6.9069 (2.51); 6.8959 (1.35); 6.0596 (0.82); 6.0387 (0.99); 6.0294 (0.96); 6.0083 (0.85); 5.7568 (4.98); 5.4611 (0.56); 5.4187 (1.96); 5.3786 (1.96); 5.3359 (0.57); 4.3710 (0.58); 4.3381 (0.60); 4.0555 (0.54); 4.0376 (1.65); 4.0199 (1.70); 4.0020 (0.81); 3.9798 (0.93); 3.9492 (1.13); 3.9360 (0.95); 3.9057 (0.76); 3.6227 (0.89); 3.6017 (0.88); 3.5790 (0.72); 3.5583 (0.73); 3.5168 (16.00); 3.4319 (0.39); 3.4129 (0.48); 3.4033 (0.84); 3.3945 (0.48); 3.3749 (0.44); 3.3186 (37.32);

Z.2721 (0.78); 3.2430 (0.45); 2.8721 (0.41); 2.8424 (0.73); 2.8145 (0.42); 2.6745 (0.52); 2.6700 (0.70); 2.6659 (0.52); 2.5403 (0.49); 2.5233 (2.23); 2.5098 (39.41); 2.5055 (77.57); 2.5011 (100.67); 2.4966 (72.91); 2.4924 (35.75); 2.3322 (0.55); 2.3278 (0.73); 2.3232 (0.53); 2.1484 (0.54); 21161 (1.06); 2.0820 (0.60); 1.9885 (7.11); 1.8259 (0.50); 1.8007 (0.44); 1.5897 (0.48); 1.5679 (0.44); 1.1921 (1.95); 1.1743 (3.87); 1.1565 (1.91); 0.0079 (1.54); -0.0002 (39.27); -0.0084 (1.49

Pr. I-51, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0556 (5.53); 7.6263 (0.39); 7.6233 (0.37); 7.5970 (0.38); 7.5183 (0.76); 7.5142 (0.91); 7.4972 (1.23); 7, A708 (0.72); 7.4662 (0.88); 7.4553 (2.83); 7.4509 (3.33); 7.4365 (0.53); 7.4268 (1.03); 7.4208 (0.68); 7.4083 (0.75); 7.4052 (0.57); 7.4017 (0.54); 7.3929 (0.37); 7.3865 (0.34); 6.9988 (0.90); 6.8616 (2.24); 6.7245 (1.02); 6.2932 (2.00); 6.0090 (0.72); 5.9896 (0.86); 5.9812 (0.85); 5.9617 (0.74); 5.7561 (13.57); 5.2591 (0.42); 5.2168 (1.44); 51704 (1.41); 51278 (0.42); 4.3845 (0.39); 4.3522 (0.42); 3.9982 (1.00); 3.9702 (1.25); 3.9548 (1.06); 3.9269 (0.80); 3.5544 (16.00); 3.3878 (0.36); 3.3781 (0.73); 3.3640 (1.15); 3.3444 (1.56); 3.3407 (1.37); 3.3234 (283.77); 3.3006 (2.02); 3.2862 (0.49); 3.2543 (0.65); 2.8215 (0.50); 2.6749 (0.54); 2.6703 (0.76); 2.6658 (0.58); 2.5405 (0.35); 2.5238 (2.32); 2.5191 (3.26); 2.5104 (41.19); 2.5059 (85.51); 2.5013 (114.44); 2.4967 (83.67); 2.4921 (40.93); 2.3326 (0.55); 2.3280 (0.76); 2.3235 (0.57); 2.1852 (9.07); 2.1253 (0.39); 2.0953 (0.78); 2.0737 (2.12); 1.7872 (0.36); 1.7661 (0.32); 1.5679 (0.32); 1.5578 (0.34); 1.5375 (0.35); 1.5280 (0.937); 1.2343 (0.46); 0.0080 (0.63); -0.0002 (22.59); -0.0085 (0.75

Pr. I-52, Solvent: dmMoo-ab6, spectrometer: 399.95 MHz 8.0458 (5.82); 8.0181 (2.17); 7.5876 (0.54); 7.5831 (0.81); 7.5677 (2.25); 7.5631 (2.32); 7.5582 (2.19); 7.5386 (2.92); 7.5187 (1.43); 74907 (2.07); 7.4861 (2.09); 7.4712 (1.22); 7.4666 (1.10); 7.0486 (1.50); 7.0294 (1.82); 6.9980 (1.98); 6.8574 (1.12); 6.8411 (0.94); 6.1918 (0.90); 6.1645 (1.30); 6.1615 (1.27); 6b, 1339 (0.95); 5.7544 (6.26); 4.1778 (1.06); 4.1444 (1.13); 4.0557 (0.33); 4.0378 (0.99); 4.0200 (0.99); 4.0023 (0.34); 3.8653 (0.72); 3.8344 (0.89); 3.8220 (1.13); 3.7913 (0.93); 3.5952 (1.09); 3.5680 (1.06); 3.5519 (0.88); 3.5294 (16.00); 3.5038 (0.37); 3.3497 (170.62); 3.3468 (168.14); 3.3343 (235.75); 3.0108 (0.80); 2.9815 (1.43); 2.9528 (0.81); 2.6805 (0.35); 2.6759 (0.74); 2.6713 (1.01); 2.6667 (0.76); 2.,65623 (0.36); 2.5414 (0.51); 2.5385 (0.47); 2.5247 (3.04); 2.5200 (4.37); 2.5113 (55.61); 2.5068 (110.08); 2.5022 (146.26); 24976 (105.83); 2.4930 (50.84); 2.3382 (0.35); 2.3335 (0.73); 2.3289 (1.01); 2.3244 (0.72); 2.3197 (0.34); 2.2329 (9.08); 2.1104 (9.43); 2.0731 (0.95); 2.0667 (1.06); 1.9885 (4.50); 1.6994 (0.32); 1.6707 (0.81); 1.6415 (0.77); 1.1924 (1.23); 1.1746 (2.45); 1.1568 (1.20); - 0.0002 (9.58

Pr. I-53, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0126 (10.74); 8.0044 (0.33); 7.4015 (0.50); 7.3868 (6.29); 7.3803 (3.89); 7.3715 (6.48); 7.3550 (1.20); 7.3511 (0.80); 7.3401 (2.26); 7.3332 (1.64); 7.3277 (1.14); 7.3181 (1.60); 7.3099 (1.92); 7.3001 (0.75); 7.1766 (4.01); 7.1662 (2.03); 7.0435 (1.91); 7.0303 (4.62); 6.9057 (3.73); 6.8945 (2.28); 5.9978 (1.53); 5.9779 (1.85); 5.9701 (1.80); 5.9501 (1.59); 5.4553 (0.83); 5.4128 (2.97); 5.3726 (2.95); 5.3300 (0.87); 5.2030 (0.44); 5.1880 (0.88); 5.1732 (0.44); 5.0692 (0.85); 4.7080 (9.99); 4.6733 (2.24); 4.6554 (0.67); 4.6448 (4.43); 4.5978 (4.59); 4.5740 (0.53); 4.5692 (2.31); 4.5582 (0.47); 4.4629 (0.43); 4.4582 (1.04); 4.4521 (1.09); 4.3620 (0.86); 4.3286 (0.88); 4.2308 (6.02); 4.2286 (6.75); 42250 (6.92); 42226 (6.83); 42187 (6.29); 4.2126 (5.63); 4.2011 (1.09); 4.1938 (8.90); 4.1829 (0.43); 4.1651 (0.87); 4.1604 (0.54); 4.1561 (0.77); 4.1166 (0.41); 4.1109 (0.45); 4.0457 (1.17); 4.0397 (1.23); 4.0308 (1.18); 4.0247 (1.20); 3.9811 (1.01); 3.9776 (1.00); 3.9678 (0.74); 3.9644 (0.81); 3.9610 (0.62); 3.9510 (0.96); 3.9474 (1.08); 3.9326 (1.78); 3.9047 (1.72); 3.8892 (1.91); 3.8615 (1.61); 3.5531 (0.36); 3.5251 (2.21); 3.5191 (4.63); 3.5133 (2.23); 3.4560 (1.01); 3.4500 (1.97); 3.4439 (1.02); 3.4241 (0.35); 3.4181 (0.75); 3.4117 (0.68); 3.3995 (0.51); 3.3907 (0.70); 3.3811 (1.21); 3.3716 (0.69); 3.3617 (0.53); 3.3520 (0.69); 3.3422 (0.69); 3.93222 (242.22); 3.2984 (2.23); 3.2829 (2.23); 3.2629 (2.97); 3.2495 (0.86); 3.2431 (1.36); 3.2396 (2.01); 3.2198 (1.86); 2.8628 (0.59); 2.8326 (1.05); 2.8039 (0.58); 2.6749 (0.73); 2.6703 (1.07); 2.65657 (0.77); 2.6610 (0.37); 2.5238 (2.69); 2.5191 (3.88); 2.5103 (56.34); 2.5058 (119.09); 2.5012 (160.97); 2.4966 (118.57); 2.4921 (58.81); 2.3372 (0.52); 2.3326 (0.96); 2.3280 (1.28); 2.3235 (0.99); 2.3190 (0.57); 2.1301 (0.80); 2.0975 (1.65); 2.0761 (0.81); 2.0739 (0.88); 2.0647 (1.17); 2.0550 (16.00); 2.0345 (0.41); 1.9885 (0.40); 1.8803 (0.933); 1.8427 (0.34); 1.8366 (0.42); 1.8147 (0.72); 1.8065 (0.78); 1.7838 (0.70); 1.7 754 (0.68); 1.6021 (0.37); 1.5811 (0.69); 1.5723 (0.77); 1.5512 (0.73); 1.5420 (0.71); 1.5202 (0.36); 1.3355 (0.49); 1.2518 (1.38); 1.2387 (1.59); 0.0080 (1.29); -0.0002 49.62); -0.0085 (1.79

Pr. I-54, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.1523 (2.53); 8.0471 (5.78); 7.5870 (0.59); 7.5824 (0.85); 7.5670 (2.36); 7.5624 (2.45); 7.5578 (2.92); 7.5383 (3.04); 7.5184 (1.50); 7.4904 (2.15); 7.4858 (2.16); 7.4709 (1.23); 7.4663 (1.12); 7.3308 (2.05); 7.3253 (2.28); 7.2014 (1.61); 7.1805 (2.25); 7.0871 (1.67); 7.0815 (1.63); 7.0669 (1.21); 7.0612 (1.19); 6b, 1914 (0.94); 6.1641 (1.37); 6.1612 (1.37); 6.1336 (0.99); 5.7537 (6.09); 4.1770 (1.18); 4.1436 (1.25); 4.0557 (0.51); 4.0380 (1.54); 4.0202 (1.56); 4.0024 (0.54); 3.8644 (0.76); 3.8336 (0.94); 3.8211 (1.19); 3.7906 (0.98); 3.5940 (1.15); 3.5668 (1.12); 3.5508 (0.92); 3.5286 (16.00); 3.9527 (169.01); 3.93502 (170.89); 3.3406 (250.87); 3.2636 (0.40); 3.0401 (0.89); 3.0101 (1.57); 2.9818 (0.90); 2.6763 (0.55); 2.68717 (0.80); 2.6671 (0.57); 2.5418 (0.43); 2.5389 (0.39); 2.5251 (2.41); 2.5204 (3.30); 2.5117 (40.30); 2.5072 (83.34); 2.5026 (111.70); 2.4979 (82.11); 2.4934 (40.17); 2.3339 (0.55); 2.3293 (0.75); 2.3248 (0.57); 2.1555 (11.75); 2.1075 (1.02); 2.0818 (1.16); 2.0732 (1.29); 1.9886 (7.00); 1.7144 (0.95); 1.6859 (0.89); 1.6561 (0.84); 1.4066 (0.87); 1.2353 (0.35); 1.1925 (1.89); 1.1747 (3.78); 1.1569 1.83); -0.0002 (2.80

Pr. I-55, Solvent: SOZSM, spectrometer: 399.95 MHz 8.2627 (0.37); 7.7237 (9.96); 7.5185 (1.53); 7.5151 (1.65); 7.4979 (2.68); 7.4596 (1.44); 74562 (1.71); 7.4499 (1.22); 7.4384 (3.30); 7.4309 (3.17); 7.4270 (1.80); 7.4124 (1.74); 7.4081 (1.14); 7.3958 (2.21); 7.3919 (2.29); 7.3774 (1.97); 7.3737 (2.17); 7.3590 (0.75); 7.3554 (0.71); 7.0621 (2.28); 6.9503 (2.49); 6.9271 (4.73); 6.8575 (3.93); 6.8135 (5.09); 6.7921 (2.37); 6.6767 (2.56); 6.0188 (1.81); 5.9978 (1.99); 5.9909 (2.02); 5.9699 (1.87); 5.3019 (0.80); 5.2597 (4.71); 5.2342 (4.66); 5.1986 (16.00); 4.5045 (0.97); 4.4711 (1.01); 4.1156 (1.11); 4.0978 (3.38); 4.0799 (3.42); 4.0621 (1.16); 3.9591 (2.78); 3.9311 (2.60); 3.9162 (3.73); 3.8883 (2.58); 3.4154 (0.46); 3.4057 (0.89); 3.3962 (0.54); 3.3868 (0.99); 3.3770 (1.89); 3.3678 (3.58); 3.3580 (0.81); 3.3470 (3.98); 3.3392 (0.76); 3.3249 (2.89); 3.3164 (1.48); 3.3040 (2.53); 3.2876 (0.77); 3.2810 (0.73); 2.9267 (0.83); 2.9198 (0.78); 2.8893 (1.28); 2.8626 (0.72); 2.8566 (0.72); 2.2326 (407.13); 2.1497 (1.57); 2.1437 (1.50); 2.1374 (1.23); 2.1912 (0.77); 2.1251 (0.50); 21167 (0.49); 2.0823 (33.19); 2.0746 (1.37); 2.0017 (15.57); 1.9943 (3.08); 1.9880 (2.12); 1.9823 (31.69); 1.9762 (60.64); 1.9700 (87.35); 1.9638 (60.83); 1.9576 (31.78); 1.9317 (0.67); 1.9198 (0.68); 1.9012 (0.99); 1.8912 (1.03); 1.8694 (0.90); 1.8601 (0.89); 1.8387 (0.47); 1.8292 (0.39); 1.8046 (0.45); 1.7984 (0.60); 1.7922 (0.44); 1.7689 (0.46); 1.7578 (0.51); 1.7379 (0.95); 1.7279 (1.01); 1.7069 (0.90); 1.6961 (0.89); 1.6770 (0.42); 1.6663 (0.38); 1.3052 (0.32); 1.3008 (0.34); 1.2507 (4.14); 1.2329 (8.10); 1.2151 (4.07

Pr. I-56, Solvent: DMOSO-ab, spectrometer: 399.95 MHz 8.0338 (6.14); 8.0183 (7.46); 7.4379 (0.96); 7.4358 (0.95); 7.4278 (1.06); 7.4216 (2.08); 7.4178 (2.31); 7, A129 (2,21); 7.4060 (1.43); 7.3933 (1.85); 7.3840 (2.85); 7.3731 (1.74); 7.3665 (6.53); 7.3539 (5.06); 7.3456 (2.29); 7.3423 (1.69); 7.3098 (2.18); 7.1765 (5.02); 7.1651 (2.50); 7.0434 (2.41); 7.0292 (5.76); 6.9057 (4.84); 6.8933 (2.79); 6.0757 (0.85); 6.0681 (1.07); 6.0548 (1.07); 6.0475 (2.00); 6.0410 (1.91); 6.0270 (0.94); 6.0196 (1.10); 5.4565 (1.14); 5.4137 (3.83); 5.3712 (3.83); 5.3287 (1.19); 4.3904 (1.46); 4.3571 (2.59); 4.3298 (1.18); 4.2933 (1.10); 4.2600 (2.68); 42310 (2.71); 4.1980 (1.06); 4.1311 (1.78); 4.0975 (1.44); 4.0555 (1.19); 4.0377 (3.54); 4.0199 (3.59); 4.0021 (1.91); 3.9796 (1.05); 3.9524 (2.38); 3.9250 (1.91); 3.9089 (1.97); 3.8816 (1.70); 3.7588 (0.41); 3.7458 (1.44); 3.7341 (2.05); 3.7282 (2.66); 3.7163 (3.35); 3.7063 (2.37); 3.6948 (1.06); 3.6899 (0.75); 3.6846 (1.03); 3.6802 (0.62); 3.6683 (0.37); 3.6578 (0.32); 3.5066 (0.39); 3.4948 (0.41); 3.4605 (0.82); 3.4486 (0.71); 3.4126 (2.31); 3.3426 (2249.46); 3.3023 (7.89); 3.2864 (40.00); 3.2638 (4.14); 3.2590 (4.07); 3.2428 (2.36); 3.2337 (1.89); 3.1926 (1.16); 3.1782 (1.16); 3.1748 (1.19); 3.1712 (1.28); 3.1592 (1.70); 3.1531 (1.19); 3.1447 (1.35); 3.1379 (1.73); 3.1271 (1.04); 3.1231 (1.15); 3.1195 (1.143; 3.1056 (0.87); 3.0913 (0.36); 2.9851 (0.85); 2.9747 (1.52); 2.9639 (0.90) ; 2.9513 (0.73); 2.9411 (1.20); 2.9303 (0.65); 2.9002 (0.68); 2.8900 (1.42); 2.8786 ( 0.76); 2.8665 (1.22); 2.8564 (1.28); 2.8318 (1.49); 2.8043 (0.88); 2.6803 (0.97); 2.6759 (2.11); 2.6714 (2.97); 2.6669 (2.20); 2.6624 (1.10); 2.5416 (1.59); 2.5388 (1 .32); 2.5248 (8.52); 2.5201 (12.03); 2.5113 (151.12); 2.5069 (315.17); 2.5023 (424 24); 2, 4977 (313.94); 2.4933 (156.51); 2.3380 (0.98); 2.3336 (2.09); 2.3290 (2.93); 2.3245 (2.21); 2.3201 (1.135); 2.1309 (1.00); 2.0981 (2.06); 2.0732 (2.80); 2.0645 (1.18); 1.9885 (16.00 ); 1.8392 (0.46); 1.8175 (0.91); 1.8096 (0.97); 1.7863 (0.88); 1.7784 (0.84); 1.7576 (0.38); 1.6856 (0.61); 1.6123 (0.38); 1.6022 (0.47); 1.5807 (0.90); 1.5712 (1.01) ; 1.5503 (0.90); 1.5418 (0.90); 1.5198 (0.40); 1.5107 (0.34); 1.2351 (1.16); 1.1923 ( 4.26); 1.1745 (8.36); 1.1568 (4.14); 0.8536 (0.34); -0.0002 (0.84

Pr. I-57, Solvent: СсОоЗсМ, spectrometer: 399.95 MHz 7.71119 (4.70); 7.5390 (0.74); 7.5362 (0.77); 7.5194 (1.26); 7.4678 (0.50); 7.4636 (0.57); 7.4503 (0.81); 7.4462 (1.05); 7.4306 (1.00); 7.4274 (0.90); 7.4149 (1.69); 7.4118 (1.11); 7.3959 (1.12); 7.3923 (1.13); 7.3758 (0.90); 7.3593 (0.34); 7.0340 (1.00); 6.9215 (1.07); 6.8990 (2.06); 6.8283 (1.69); 6.7847 (2.19); 6.7640 (1.03); 6.6479 (1.11); 6.0625 (0.79); 6.0405 (0.92); 6.0351 (0.92); 6.0130 (0.82); 5.4486 (2.97); 52752 (0.37); 52328 (1.98); 5.2057 (1.97); 5.1633 (0.36); 4.6263 (1.09); 4.5914 (2.05); 4.5192 (2.16); 4.4841 (1.53); 4.4480 (0.44); 3.9643 (0.95); 3.9367 (1.11); 3.9208 (1.52); 3.8933 (1.43); 3.8376 (1.48); 3.8238 (3.07); 3.8103 (2.03); 3.3948 (16.00); 3.3750 (1.48); 3.3605 (0.63); 3.3508 (2.03); 3.3355 (1.95); 3.3318 (1.68); 3.3213 (2.51); 3.3093 (1.49); 3.2927 (0.55); 3.2820 (0.79); 3.2581 (0.35); 2.8566 (0.54); 2.2049 (173.16); 2.1713 (1.05); 2.1208 (0.56); 2.1146 (0.50); 2.1082 (0.39); 1.9651 (1.68); 1.9591 (1.50); 1.9532 (12.46); 1.9470 (23.29); 1.9409 (32.44); 1.9347 (22.47); 1.9285 (11.66); 1.8744 (0.41); 1.8645 (0.42); 1.8426 (0.37); 1.8332 (0.937); 1.7086 (0.40); 1.6984 (0.41); 1.6774 (0.38); 1.6671 0.37); -0.0002 (0.43

Pr. I-58, Solvent: DMOSO-ab, spectrometer: 399.95 MHz 8.0460 (11.12); 7.4923 (2.15); 7.4855 (2.31); 7.4703 (2.61); 7.4635 (2.90); 7.3348 (4.21); 7.3282 (3.687); 7.3116 (1.80); 7.2623 (5.28); 7.2401 (4.38); 7.1783 (4.26); 7.1690 (2.02); 7.0452 (2.07); 7.0330 (4.74); 6.9085 (3.84); 6.8972 (2.32); 5.8820 (1.52); 5.8649 (1.76); 5.8542 (1.71); 5.8371 (1.55); 5.7593 (9.93); 5.4595 (1.00); 5.4169 (3.12); 5.3740 (3.11); 5.3313 (0.99); 5.2636 (16.00); 5.2340 (0.33); 4.3623 (0.89); 4.3290 (0.93); 4.0555 (0.51); 4.0376 (1.55); 4.0198 (1.57); 4.0020 (0.59); 3.9795 (0.83); 3.9439 (2.43); 3.9159 (1.91); 3.9006 (2.13); 3.8728 (1.70); 3.4161 (0.34); 3.4068 (0.62); 3.3973 (0.46); 3.3873 (0.78); 3.3779 (1.38); 3.3686 (0.82); 3.3584 (0.67); 3.3487 (1.09); 3.3300 (100.26); 3.3040 (2.42); 3.2879 (0.77); 3.27 79 (1.99); 3.2608 (2.85); 3.2300 (0.65); 3.2084 (0.43); 3.1731 (0.42); 2.8632 (0.55); 2.8571 (0.65); 2.8304 (1.10); 2.8267 (1.12); 2.7995 (0.64); 2.6712 (0.41); 2.5246 (1.09); 2.5112 (21.74); 2.5067 (44.31); 2.5021 (59.27); 2.4976 (42.68); 2.4931 (20.06); 2.3289 (0.41); 2.1249 (0.75); 2.0906 (1.60); 2.0559 (0.89); 1.9894 (6.73); 1.8332 (0.32); 1.8191 (0.71); 1.8046 (0.74); 1.7826 (0.70); 1.7738 (0.64); 1.5968 (0.36); 1.5761 (0.72); 1.5665 (0.79); 1.5453 (0.73); 1.5360 (0.70); 1.1924 (1.84); 1.1746 (3.68); 1.1568 (1.79); 0.0080 (0.47); -0.0002 (13.59); -0.0085 (0.43

Pr. I-59, Solvent: DMOSO-ab, spectrometer: 399.95 MHz 8.0704 (5.84); 7.5658 (0.87); 7.5594 (1.02); 7.5438 (1.76); 7.5374 (2.28); 7.5037 (3.81); 7.4936 (2.67); 7.4872 (2.27); 7.4818 (2.02); 7.3141 (0.96); 7.1808 (2.24); 7.1702 (1.07); 7.0477 (1.09); 7.0342 (2.49); 6.9096 (2.19); 6.8984 (1.24); 5.9877 (0.88); 5.9686 (1.04); 5.9598 (1.01); 5.9406 (0.90); 5.7593 (7.54); 5.4636 (0.55); 5.4209 (1.74); 5.3767 (1.71); 5.3339 (0.54); 4.3678 (0.51); 4.3349 (0.53); 4.0557 (0.33); 4.0379 (1.00); 4.0199 (1.38); 4.0023 (0.44); 3.9895 (1.33); 3.9742 (1.39); 3.9462 (1.36); 3.5920 (16.00); 3.5574 (0.32); 3.4234 (1.17); 3.4043 (1.19); 3.3894 (0.79); 3.3800 (1.33); 3.3704 (0.35); 3.3609 (1.30); 3.3296 (21.94); 3.2933 (0.39); 3.2627 (0.67); 3.2341 (0.37); 2.8617 (0.36); 2.8311 (0.63); 2.8041 (0.36); 2.5248 (0.32); 2.5113 (7.66); 2.5069 (15.93); 2.5024 (21.57); 2.4978 (16.00); 2.4934 (7.86); 2.1328 (0.43); 2.0992 (0.92); 2.0632 (0.51); 1.9896 (4.33); 1.8196 (0.39); 1.8113 (0.42); 1.7893 (0.39); 1.7809 (0.36); 1.5805 (0.40); 1.5712 (0.44); 1.5502 (0.41); 1.5410 (0.39); 1.1926 (1.20); 1.1748 (2.40); 1.1570 (1.17); -0.0002 (2.03

Pr. I-60, Solvent: DMOSO-ab, spectrometer: 399.95 MHz 8.5181 (3.89); 8.0345 (5.47); 7.5641 (0.96); 7.5447 (1.49); 7.4987 (0.51); 7.4853 (0.59); 7.4788 (0.90); 7.4652 (0.87); 7.4588 (0.50); 7.4448 (0.41); 7.3522 (0.65); 7.3314 (0.59); 7.3267 (0.72); 7.3136 (0.92); 7.3061 (0.56); 7.1806 (1.99); 7.1670 (0.93); 7.0472 (0.98); 7.0310 (2.25); 6.9066 (1.98); 6.8952 (1.12); 6b, 2255 (0.60); 6.1979 (0.93); 6.1703 (0.62); 5.7549 (5.04); 5.4602 (0.40); 5.4175 (1.48); 5.3775 (1.49); 5.3341 (0.43); 4.3709 (0.42); 4.3347 (0.42); 4.0381 (0.47); 4.0201 (0.47); 4.0021 (0.34); 3.9874 (0.40); 3.9582 (0.45); 3.9297 (0.51); 3.9067 (16.00); 3.8874 (0.55); 3.8831 (0.56); 3.8570 (0.46); 3.4788 (0.61); 3.4524 (0.62); 3.4341 (0.67); 3.4110 (0.77); 3.4038 (0.69); 3.3941 (0.42); 3.3842 (0.33); 3.3740 (0.40); 3.3270 (223.89); 3.3037 (1.83); 3.2756 (0.58); 3.2452 (0.35); 2.8483 (0.59); 2.6706 (0.35); 2.5237 (0.55); 2.5057 (39.36); 2.5017 (55.52); 2.4980 (37.72); 2.3281 (0.36); 2.1510 (0.97); 2.1178 (0.76); 2.0827 (0.45); 2.0734 (0.90); 1.9884 (2.05); 1.8262 (0.38); 1.5988 (0.36); 1.5895 (0.38); 1.5665 0.35); 1.1923 (0.56); 1.1744 (1.07); 1.1567 (0.51); -0.0002 (0.70

Pr. I-61, Solvent: DMOSO-ab, spectrometer: 399.95 MHz 9.9006 (0.39); 8.7856 (0.65); 8.6549 (0.38); 8.2190 (0.39); 8.0730 (0.44); 8.0597 (7.90); 7.5150 (1.26); 7.4978 (2.03); 7.4761 (0.33); 7.4708 (1.17); 7.4664 (1.47); 7.4597 (2.25); 74524 (4.76); 7.4410 (0.78); 7.4285 (1.61); 7.4216 (1.02); 74137 (0.84); 7.4099 (1.11); 7.4023 (0.75); 7.3960 (0.58); 7.3879 (0.48); 6.4976 (4.78); 6.0279 (1.11); 6.0088 (1.27); 6.0001 (1.18); 5.9811 (1.09); 5.7546 (2.27); 5.3500 (0.81); 5.3076 (2.45); 5.2561 (2.59); 5.2136 (0.83); 4.3850 (0.69); 4.3550 (0.73); 4.0561 (0.95); 4.0383 (2.96); 4.0205 (3.08); 4.0065 (1.18); 4.0028 (1.40); 3.9785 (1.66); 3.9630 (1.75); 3.9350 (1.21); 3.5538 (0.66); 3.4101 (0.61); 3.3998 (0.45); 3.3892 (0.76); 3.3810 (2.31); 3.3713 (0.86); 3.3618 (1.89); 3.3384 (109.04); 3.39327 (213.96); 3.3190 (3.36); 3.2860 (0.72); 3.2739 (1.20); 3.2661 (1.69); 3.2626 (1.56); 3.2542 (1.99); 3.2470 (0.72); 3.2425 (1.10); 3.2346 (1.36); 3.2228 (0.62); 2.8627 (0.54); 2.8334 (0.87); 2.8052 (0.49); 2.6713 (0.41); 2.5250 (0.59); 2.5108 (21.58); 2.5066 (41.82); 2.5023 (58.21); 2.4981 (40.48); 2.4938 (20.30); 2.3666 (0.36); 2.3290 (0.41); 22072 (16.00); 2.1942 (0.95); 2.1328 (0.69); 21019 (1.33); 2.0734 (1.43); 1.9887 (19.29); 1.8231 (0.58); 1.8132 (0.62); 1.7912 (0.57); 1.5989 (0.33); 1.57 78 (0.56); 1.5674 (0.58); 1.5463 (0.58); 1.5378 (0.56); 1.2766 (0.33); 1.2618 (1.03); 1.2533 (1.59); 1.2490 (1.72); 1.2435 (1.55); 1.2335 (1.77); 1.2293 (1.70); 1.2244 (1.31); 1.2150 (0.51); 1.2073 (0.45); 1.1926 (3.69); 1.1748 (7.41); 1.1638 (0.60); 1.1570 (3.85); 1.1524 (0.82); 1.1436 (0.84); 1.1392 1.64); 1.1281 (2.02); 1.1172 (1.51); 1.1083 (0.77); 1.1012 (0.55); 1.0912 (0.32); -0.0002 (0.76

Pr. I-62, Solvent: DMOSO-ab, spectrometer: 399.95 MHz 12.2016 (0.36); 8.0570 (5.83); 7.5158 (1.11); 7.4975 (1.59); 7.4773 (0.43); 7.707 (0.93); 7.4664 (0.92); 7.4551 (3.16); 7.4507 (3.82); 7.4355 (0.75); 7.4263 (1.24); 7.4082 (1.02); 7.3936 (0.55); 7.3863 (0.43); 7.1292 (0.39); 6.4974 (3.47); 6.0092 (0.81); 5.9901 (1.07); 5.9810 (0.96); 5.9615 (1.02); 5.7554 (2.66); 5.3505 (0.74); 5.3072 (1.97); 5.2558 (1.83); 5.2128 (0.74); 4.3815 (0.61); 4.3541 (0.73); 4.0375 (0.36); 4.0192 (0.47); 3.9986 (1.18); 3.9861 (0.74); 3.9710 (1.17); 3.9554 (1.61); 3.9273 (0.99); 3.7205 (0.68); 3.5536 (16.00); 3.5166 (0.50); 3.4117 (0.63); 3.3904 (0.76); 3.3819 (1.12); 3.3644 (1.68); 3.3478 (7.73); 3.3233 (950.73); 3.2622 (1.19); 3.2337 (0.80); 3.2149 (0.38); 3.2008 (0.37); 2.8635 (0.65); 2.8486 (0.39); 2.8344 (0.76); 2.8021 (0.59); 2.6904 (0.44); 2.6750 (1.54); 2.6704 (2.18); 2.6666 (1.50); 2.5407 (1.143; 2.5238 (3.87); 2.5056 (247.76); 2.5014 (339.80); 2.4972 (241.82); 2.3719 (0.39) ; 2.3280 (2.01); 2.3236 (1.47); 2.2064 (11.63); 2.1285 (0.66); 2.1031 (1.08); 2.0855 ( 2.04); 2.0733 (1.58); 1.9886 (1.57); 1.9082 (0.60); 1.8497 (0.39); 1.8239 (0.59); 1.8141 (0.70); 1.7940 (0.51); 1.7800 (0.62); 1.5719 (0.52); 1.5452 (0.49); 1.5396 (0 .50); 1.3356 (0.37); 1.2975 (0.39); 1.2356 (1.30); 1.2142 (0.53); 1.1919 (0.47); 1 .1746 (0.88); 1.1576 (0.49); 1.1262 (1.17); 1.1094 (0.88); 0.9937 (0.50); 0.9773 0.36 ); 0.9398 (0.49); 0.9227 (0.92); 0.9049 (0.52); 0.851 7 (0.42); -0.0002 (8.92); -3.2437 (0.37

Pr. I-63, Solvent: dmeoo-ab, spectrometer: 399.95 MG 8.0323 (11.61); 7.4199 (1.00); 7.4156 (1.23); 7.3969 (2.07); 7.3767 (3.97); 7.3580 (2.70); 7.3542 (2.03); 7.3131 (1.77); 7.2179 (3.31); 7.1983 (2.77); 7.1798 (4.26); 7.1725 (2.14); 71161 (1.77); 7.0976 (3.09); 7.0789 (1.44); 7.0468 (2.03); 7.0365 (4.95); 6.9137 (3.98); 6.9007 (2.33); 5.9041 (1.52); 5.8863 (1.75); 5.8765 (1.72); 5.8584 (1.57); 5.7619 (10.05); 5.4619 (1.05); 5.4192 (3.22); 5.3761 (3.15); 5.3334 (1.06); 5.2468 (16.00); 4.3622 (0.91); 4.3290 (0.95); 4.0547 (0.62); 4.0369 (1.92); 4.0191 (1.94); 4.0013 (0.70); 3.9785 (0.84); 3.9449 (0.92); 3.9206 (1.69); 3.8926 (1.96); 3.8776 (2.17); 3.8497 (1.77); 3.4047 (1.58); 3.3723 (293.23); 3.3690 (261.26); 3.3664 (285.62); 3.2911 (2.77); 3.2732 (2.40); 3.2564 (1.47); 3.2482 (2.46); 3.2302 (2.51); 2.8554 (0.68); 2.8249 (1.17); 2.7981 (0.68); 2.6780 (0.48); 2.6736 (0.66); 2.6690 (0.49); 2.5437 (0.32); 2.5269 (1.01); 2.5222 (1.68); 2.5135 (34.32); 2.5090 (73.90); 2.5045 (98.84); 2.4999 (69.67); 2.4953 (32.50); 2.3358 (0.48); 2.3311 (0.66); 2.3265 (0.48); 21223 (0.79); 2.0895 (1.67); 2.0771 (3.02); 2.0556 (0.93); 1.9904 (8.99); 1.8324 (0.37); 1.8116 (0.74); 1.6027 (0.62); 1.7806 (0.76); 1.7718 (0.68); 1.5928 (0.37); 1.5725 (0.73); 1.5624 (0.82); 1.5415 (0.77); 1.5326 (0.74); 1.5114 (0.32); 1.1921 (2.38); 1.1743 (4.71); 1.1565 (2.32); -0.0002 (2.37

Pr. I-64, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0515 (11.26); 8.0009 (0.32); 7.5154 (2.02); 7.4979 (3.18); 7.4701 (1.93); 7.4654 (2.56); 74586 (3.95); 7.4515 (6.91); 7.4398 (1.21); 7.4276 (2.26); 7.4207 (1.62); 7.4126 (1.34); 7.4092 (1.73); 7.4015 (1.20); 7.3953 (0.82); 7.3872 (0.77); 7.3049 (1.90); 7.1716 (4.43); 7.1573 (2.16); 7.0384 (2.23); 7.0214 (4.90); 6.8995 (4.33); 6.8854 (2.37); 6.0255 (1.69); 6.0058 (2.05); 5.9976 (1.91); 5.9781 (1.67); 5.4501 (0.91); 5.4071 (3.23); 5.3647 (3.20); 53234 (0.687); 4.3626 (1.06); 4.3295 (1.12); 4.0569 (1.39); 4.0392 (3.76); 4.0214 (3.92); 4.0034 (2.98); 3.9751 (2.83); 3.9595 (2.85); 3.9318 (2.35); 3.8410 (0.35); 3.8049 (0.95); 3.7566 (0.38); 3.6799 (0.48); 3.5379 (0.80); 3.4137 (3.47); 3.3803 (8.56); 3.3237 (3309.80);

Z,2742 (4.46); 3.2627 (4.06); 3.2547 (3.16); 3.2426 (3.90); 3.2310 (2.69); 3.2231 (1.95); 3.2111 (1.12); 3.1950 (0.37); 2.8667 (0.71); 2.8385 (1.19); 2.8097 (0.71); 2.6750 (1.01); 2.6704 (1.32); 2.6656 (0.99); 2.5663 (0.64); 2.5402 (1.92); 2.5101 (79.14); 2.5057 (147.64); 2.5013 (193.09); 2.4969 (134.97); 2.4925 (65.81); 2.3328 (0.97); 2.3279 (1.35); 2.3231 (0.94); 2.1328 (0.96); 2.0987 (1.88); 2.0686 (3.91); 1.9868 (16.00); 1.8381 (0.43); 1.8091 (0.89); 1.7849 (0.78); 1.6042 (0.44); 1.5727 (0.82); 1.5530 (0.81); 1.5445 (0.77); 1.3982 (1.09); 1.2896 (0.35); 1.2775 (0.56); 1.2618 (1.55); 1.2532 (3.06); 1.2492 (3.05); 1.2439 (2.66); 1.2335 (3.09); 1.2293 (2.96); 1.2248 (2.25); 1.2151 (0.90); 1.2080 (0.88); 1.1928 (4.67); 1.1750 (9.08); 1.1657 (1.23); 1.1572 (4.92); 1.1417 (2.684); 1.1312 (3.24); 1.1199 (2.58); 1.1111 (1.32); 1.1041 (0.83); 1.0938 (0.62); 1.0336 (0.79); -0.0002 (0.80

Pr. I-65, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0533 (0.76); 7.4238 (0.35); 7.0221 (0.35); 3.7167 (0.55); 3.6984 (0.56); 3.4921 (16.00); 3.1147 (0.47); 3.1026 (0.56); 3.0965 (1.48); 3.0844 (1.50); 3.0783 (1.55); 3.0662 (1.47); 3.0602 (0.59); 3.0481 (0.48); 2.5106 (3.51); 2.5062 (6.52); 2.5018 (8.50); 2.4974 (5.92); 2.4930 (2.87); 2.4439 (0.32); 2.4253 (0.93); 2.4068 (0.95); 2.3883 (0.33); 1.4461 (0.55); 1.4278 (1.16); 1.4094 (0.54); 1.2074 (2.95); 1.1892 5.92); 1.1710 (2.79); 1.0879 (1.00); 1.0694 (1.95); 1.0508 (0.93); -0.0002 (0.53

Pr. I-66, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0504 (5.83); 7.3898 (1.94); 7.3700 (2.50); 7.2602 (2.44); 7.2300 (1.38); 7.2098 (1.08); 6.4993 (3.05); 5.9571 (0.83); 5.9373 (0.98); 5.9295 (0.97); 5.9096 (0.86); 5.7590 (8.28); 5.3552 (0.67); 5.3125 (1.93); 5.2607 (1.91); 52180 (0.65); 4.3877 (0.53); 4.3545 (0.56); 4.0377 (0.87); 4.0199 (0.89); 4.0020 (0.41); 3.9865 (0.49); 3.9568 (1.28); 3.9291 (1.00); 3.9136 (1.10); 3.8858 (0.90); 3.5397 (16.00); 3.5046 (0.67); 3.4094 (0.36); 3.3899 (0.42); 3.3806 (0.75); 3.3712 (0.44); 3.3619 (0.34); 3.351 7 (0.43); 3.3383 (1.16); 3.3273 (10.92); 3.3186 (1.20); 3.3034 (0.97); 3.2949 (1.26); 3.2752 (1.05); 3.2618 (0.71); 32327 (0.38); 2.8596 (0.37); 2.8292 (0.65); 2.8022 (0.37); 2.5107 (7.29); 2.5063 (15.44); 2.5018 (21.55); 2.4973 (16.30); 2.4930 (8.09); 2.3444 (9.33); 2.2063 (11.03); 2.1939 (0.682); 2.1301 (0.48); 2.0976 (0.98); 2.0695 (0.53); 1.9893 (3.72); 1.8225 (0.42); 1.8144 (0.45); 1.7922 (0.41); 1.7835 (0.38); 1.5759 (0.41); 1.5666 (0.46); 1.5452 (0.42); 1.5365 (0.40); 1.1923 (1.01); 1.1745 (2.01); 1.1567 (0.99); 0.0080 (0.61); -0.0002 (19.18); -0.0084 (0.73

Pr. I-67, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0550 (5.79); 7.3348 (1.81); 7.3140 (4.37); 7.3077 (2.13); 7.3029 (2.33); 7.2656 (1.50); 7.2609 (1.29); 7.2443 (0.96); 7.2405 (0.84); 7.1806 (2.32); 7.1697 (1.15); 7.0475 (1.14); 7.0337 (2.58); 6.9091 (2.40); 6.8980 (1.91); 5.9660 (0.92); 5.9459 (1.10); 5.9381 (1.07); 5.9180 (0.95); 5.7589 (7.33); 5.4636 (0.59); 5.4209 (1.86); 5.3766 (1.87); 5.3340 (0.59); 4.3682 (0.55); 4.3351 (0.58); 4.0376 (0.76); 4.0198 (0.78); 4.0019 (0.35); 3.9802 (1.29); 3.9520 (1.52); 3.9367 (1.33); 3.9086 (0.95); 3.5210 (16.00); 3.4837 (0.51); 3.4174 (0.37); 3.3978 (0.44); 3.3886 (0.77); 3.3793 (0.47); 3.3562 (1.26); 3.3357 (1.44); 3.3273 (17.59); 3.9127 (1.08); 3.2927 (1.33); 3.2628 (0.72); 3.2339 (0.40); 2.8617 (0.38); 2.8309 (0.68); 2.8041 (0.39); 2.5106 (9.40); 2.5063 (19.21); 2.5018 (26.17); 2.4973 (19.61); 2.4931 (9.59); 2.3198 (10.18); 2.19324 (0.47); 2.0992 (1.00); 2.0650 (0.55); 1.9892 (3.20); 1.8197 (0.43); 1.8115 (0.46); 1.76891 (0.43); 1.7806 (0.40); 1.5802 (0.43); 1.5712 (0.48); 1.5494 (0.44); 1.5403 (0.42); 1.1922 (0.88); 1.1744 (1.74); 1.1566 (0.86); 0.0080 (0.36); -0.0002 (9.91); -0.0084 (0.35

Pr. I-68, Solvent: СсОоЗсМ, spectrometer: 399.95 MHz 7.6986 (16.00); 7.6910 (0.40); 7.4036 (1.69); 7.3897 (1.87); 7.3838 (3.23); 7.3701 (3.34); 7.3638 (2.57); 7.3500 (2.43); 7.2306 (5.11); 7.2118 (3.92); 7.1700 (2.49); 7.1491 (2.19); 7.1471 (2.22); 7.1416 (2.60); 7.1209 (2.06); 7.0345 (3.69); 6.9209 (4.01); 6.8995 (7.50); 6.8283 (6.77); 6.7841 (8.07); 6.7645 (3.79); 6.6472 (4.11); 6.0571 (2.12); 6.0300 (3.58); 6.0017 (2.23); 5.4468 (0.43); 52766 (1.37); 5.2344 (7.69); 5.2078 (7.72); 5.1827 (0.40); 5.1656 (1.40); 4.7245 (3.37); 4.6956 (9.78); 4.6701 (9.81); 4.6413 (3.26); 4.4874 (1.75); 4.4537 (1.79); 4.1883 (0.46); 4.1820 (0.71); 4.1725 (14.37); 4.1672 (14.29); 41321 (0.37); 4.1287 (0.79); 4.1226 (0.77); 4.0857 (0.54); 4.0678 (1.49); 4.0500 (1.48); 4.0321 (0.52); 3.9288 (1.61); 3.8945 (1.83); 3.8451 (1.75); 3.8398 (1.73); 3.8151 (1.77); 3.8098 (1.80); 3.8022 (2.36); 3.7969 (2.36); 3.7721 (2.18); 3.7669 (2.20); 3.5361 (2.64); 3.5334 (2.81); 3.5214 (0.38); 3.5108 (2.59); 3.5082 (2.63); 3.4933 (2.00); 3.4905 (2.05); 3.4679 (1.92); 3.4652 (2.00); 3.4009 (0.72); 3.3916 (1.45); 3.3819 (0.89); 3.3726 (1.59); 3.3629 (3.06); 3.3533 (1.69); 3.3440 (1.02); 3.3340 (1.97); 3.3293 (1.65); 33236 (1.99); 3.2929 (2.33); 3.2748 (0.78); 3.2643 (1.34); 3.2576 (1.21); 2.9009 (1.12); 2.8941 (1.27); 2.8678 (2.11); 2.8631 (2.18); 2.8371 (1.28); 2.8305 (1.19); 2.7290 (3.98); 2.7230 (7.92); 2.7171 (3.96); 2.6187 (0.34); 2.2148 (9.94); 2.1363 (2.33); 21132 (0.77); 2.1069 (0.73); 2.1008 (0.59); 2.0944 (0.46); 2.0667 (0.49); 2.0584 (0.36); 2.0526 (0.938); 1.9716 (6.63); 1.9638 (1.90); 1.9576 (2.26); 1.9518 (18.59); 1.9457 (34.92); 1.9395 (49.02); 1.9333 (34.13); 1.9271 (17.98); 1.9076 (1.24); 1.8877 (1.76); 1.8779 (1.80); 1.8558 (1.61); 1.8463 (1.56); 1.8261 (0.76); 1.8158 (0.73); 1.7741 (0.37); 1.7680 (0.48); 1.7617 (0.42); 1.7528 (0.81); 1.7423 (0.85); 1.7222 (1.63); 1.7124 (1.68); 1.6912 (1.57); 1.6808 (1.54); 1.6611 (0.72); 1.6501 (0.65); 1.4362 (0.54); 1.3716 (0.35); 1.2848 (0.37); 1.2761 (0.38); 1.2698 (0.40); 1.2212 (1.90); 1.2034 (3.52); 1.1855 (1.79); 0.0080 (1.24); -0.0002 (42.30); -0.0086 (1.68

Pr. I-69, Solvent: СсОоЗсМ, spectrometer: 399.95 MHz 7.7240 (0.44); 7.7077 (16.00); 7.4221 (1.59); 7.4082 (1.77); 7.4024 (3.25); 7.3886 (3.32); 7.3822 (2.53); 7.3683 (2.35); 7.2675 (4.90); 7.2492 (3.64); 7.1890 (2.34); 7.1871 (2.31); 7.1683 (2.10); 7.1661 (2.14); 7.1610 (2.53); 7.1589 (2.42); 7.1401 (1.99); 7.1383 (1.93); 7.0352 (3.65); 6.9211 (3.91); 6.9002 (7.47); 6.8284 (6.39); 6.7843 (7.89); 6.7651 (3.80); 6.6475 (4.01); 6.0324 (2.28); 6.0048 (3.36); 5.9770 (2.38); 5.2776 (1.40); 52350 (8.70); 5.2080 (8.30); 5.2022 (12.23); 5.1928 (11.14); 5.1653 (1.55); 5.1612 (2.04); 4.4873 (1.63); 44537 (1.70); 4.0855 (0.46); 4.0677 (1.40); 4.0498 (1.41); 4.0320 (0.48); 3.9279 (1.56); 3.8927 (1.73); 3.8766 (2.00); 3.8715 (1.84); 3.8464 (1.75); 3.8414 (1.82); 3.8335 (2.31); 3.8284 (2.35); 3.8034 (2.10); 3.7985 (2.16); 3.5579 (2.47); 3.5553 (2.50); 3.5324 (2.48); 3.5299 (2.49); 3.5149 (1.92); 3.5123 (1.95); 3.4894 (1.87); 3.4868 (1.91); 3.3953 (0.68); 3.3857 (1.42); 3.3760 (0.87); 3.3666 (1.56); 3.3570 (3.02); 3.3474 (1.61); 3.3379 (1.02); 3.3280 (2.60); 3.3199 (1.93); 3.2912 (2.23); 3.2623 (1.23); 3.2556 (1.14); 2.8982 (1.07); 2.8913 (1.21); 2.8649 (2.02); 2.8605 (2.08); 2.8343 (1.20); 2.8277 (1.12); 22152 (1.37); 2.1600 (24.21); 2.1312 (1.75); 2.0363 (0.46); 2.0002 (48.58); 1.9715 (6.47); 1.9636 (1.06); 1.9575 (1.17); 1.9517 (8.47); 1.9455 (15.87); 1.9393 (22.29); 1.93391 (15.57); 1.9269 (8.12); 1.9138 (0.84); 1.9033 (0.78); 1.8831 (1.45); 1.8733 (1.51); 1.8516 (1.937); 1.8420 (1.33); 1.8218 (0.56); 1.8112 (0.50); 1.7488 (0.64); 1.7382 (0.73); 1.7184 (1.46); 1.7083 (1.53); 1.6869 (1.40); 1.6770 (1.95); 1.6569 (0.59); 1.6463 (0.53); 1.4353 (0.33); 1.3721 (0.36); 1.2759 (0.42); 1.2208 (1.73); 1.2030 (3.40); 1.1852 (1.69); 0.0080 (0.74); -0.0002 (19.49); -0.0086 (0.74

Pr. I-70, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0605 (5.72); 7.5684 (2.18); 7.5656 (2.17); 7.5353 (0.45); 7.5134 (5.02); 7.5085 (2.66); 7.4873 (0.34); 7.3118 (0.95); 7.1785 (2.20); 7.1672 (1.05); 7.0453 (1.07); 7.0311 (2.44); 6.9068 (2.16); 6.8954 (1.20); 5.9811 (0.96); 5.9622 (1.11); 5.9533 (1.07); 5.9342 (0.95); 5.7568 (4.65); 5.4597 (0.52); 5.4171 (1.70); 5.3738 (1.68); 5.3314 (0.52); 4.3649 (0.50); 4.3321 (0.52); 4.0379 (0.56); 4.0201 (0.59); 3.9980 (0.90); 3.9800 (0.51); 3.9700 (1.23); 3.9544 (1.44); 3.9266 (0.94); 3.6178 (16.00); 3.5678 (1.28); 3.4144 (0.95); 3.3948 (0.43); 3.3857 (0.76); 3.3731 (1.24); 3.93541 (1.26); 3.3206 (18.17); 3.3109 (1.58); 3.2924 (0.44); 3.2609 (0.65); 3.2324 (0.36); 2.8605 (0.35); 2.8303 (0.62); 2.8029 (0.36); 2.5649 (0.72); 2.5238 (0.64); 2.5104 (11.64); 2.5060 (23.31); 2.5015 (30.92); 2.4969 (22.42); 2.4925 (10.71); 21283 (0.43); 2.0946 (0.91); 2.0608 (0.50); 1.9888 (2.41); 1.8160 (0.39); 1.8079 (0.42); 1.7858 (0.39); 1.7774 (0.36); 1.5781 (0.39); 1.5690 (0.44); 1.5474 (0.40); 1.5378 (0.38); 1.1924 (0.70); 1.1746 (1.40); 1.1568 0.69); 0.0080 (1.16); -0.0002 (31.29); -0.0085 (1.07

Pr. I-71, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0278 (11.11); 7.3740 (3.683); 7.3536 (9.46); 7.3492 (5.67); 7.3102 (1.684); 7.1825 (3.40); 7.1773 (6.70); 7.1666 (2.40); 7.1622 (2.76); 7.1574 (2.56); 7.0438 (2.10); 7.0307 (4.78); 6.9063 (4.22); 6.8949 (2.38); 5.8674 (1.59); 5.8500 (1.82); 5.8399 (1.77); 5.8221 (1.63); 5.7571 (15.64); 5.4569 (1.00); 5.4143 (3.34); 5.3719 (3.29); 5.3294 (1.06); 5.3002 (16.00); 5.2736 (0.40); 4.3605 (0.97); 4.3272 (1.02); 4.0379 (0.93); 4.0201 (0.96); 4.0023 (0.38); 3.9779 (0.91); 3.9438 (1.00); 3.9191 (1.64); 3.8911 (1.90); 3.8760 (2.13); 3.8482 (1.75); 3.7003 (0.37); 3.4132 (0.35); 3.4035 (0.69); 3.3945 (0.49); 3.3844 (0.81); 3.3750 (1.44); 3.3658 (0.85); 3.3558 (0.55); 3.3463 (0.83); 3.3364 (0.54); 3.3203 (39.24); 3.2935 (2.58); 3.2759 (2.13); 3.2577 (1.41); 3.2506 (2.33); 3.2329 (2.19); 2.8581 (0.71); 2.8275 (1.25); 2.8003 (0.70); 2.6749 (0.36); 2.6705 (0.50); 2.6660 (0.36); 2.5238 (1.26); 2.5104 (26.07); 2.5060 (52.87); 2.5015 (69.65); 2.4969 (49.58); 2.4926 (23.44); 2.3328 (0.36); 2.3282 (0.48); 2.3237 (0.34); 2.1222 (0.83); 2.0899 (1.78); 2.0541 (0.98); 1.9889 (4.05); 1.8313 (0.39); 1.8103 (0.79); 1.8014 (0.84); 1.7800 (0.76); 1.7713 (0.71); 1.5954 (0.38); 1.5747 (0.79); 1.5653 (0.86); 1.5441 (0.81); 1.5349 (0.77); 1.3359 (0.49); 1.2494 (0.65); 1.2348 (0.34); 1.1924 (1.12); 1.1745 (2.22); 1.1568 (1.09); -0.0002 (9.25

Pr. I-72, Solvent: dmMoo-ab6, spectrometer: 399.95 MHz 8.0488 (5.55); 7.3899 (1.89); 7.3700 (2.42); 7.3115 (0.98); 7.2602 (2.46); 7.2301 (1.37); 7.2100 (1.08); 7.1783 (2.22); 7.1669 (1.10); 7.0452 (1.09); 7.0309 (2.47); 6.9061 (2.32); 6.8952 (1.28); 5.9565 (0.82); 5.9366 (0.98); 5.9289 (0.96); 5.9090 (0.86); 5.7567 (6.92); 5.4593 (0.55); 5.4167 (1.80); 5.3737 (1.80); 5.3310 (0.56); 4.3637 (0.53); 4.3314 (0.57); 4.0378 (0.48); 4.0201 (0.51); 3.9815 (0.50); 3.9559 (1.18); 3.9282 (1.06); 3.9127 (1.11); 3.8849 (0.92); 3.5378 (16.00); 3.5036 (0.44); 3.4140 (0.36); 3.3947 (0.43); 3.3853 (0.75); 3.3760 (0.45); 3.3567 (0.42); 3.3381 (1.09); 3.3203 (22.56); 3.2949 (1.52); 32750 (1.09); 3.2614 (0.77); 3.2325 (0.40); 2.8617 (0.37); 2.8308 (0.68); 2.8037 (0.38); 2.5098 (12.48); 2.5056 (25.75); 2.5012 (34.65); 2.4967 (25.58); 2.4924 (12.84); 2.3448 (9.74); 2.3282 (0.45); 2.1304 (0.48); 2.0961 (1.01); 2.0627 (0.57); 1.9886 (1.94); 1.8183 (0.44); 1.8098 (0.48); 1.7870 (0.51); 1.7790 (0.42); 1.5790 (0.44); 1.5696 (0.48); 1.5483 (0.45); 1.5394 (0.44); 1.1922 (0.55); 1.1744 (1.07); 1.1566 (0.54); 0.0080 (0.74); -0.0002 (22.53); -0.0085 (0.95

Pr. I-73, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.2136 (0.37); 8.1646 (0.34); 8.0565 (5.61); 8.0411 (0.48); 7.5204 (0.86); 7.5165 (0.98); 7.4995 (1.45); 7.4707 (0.687); 7.4663 (1.06); 7.4555 (2.83); 7.4514 (3.81); 7.4376 (0.65); 7.4269 (1.22); 74206 (0.79); 7.4082 (0.92); 7.4016 (0.60); 7.3933 (0.41); 7.3864 (0.37); 7.2088 (0.97); 7.0742 (2.15); 6.9396 (1.05); 6.3846 (2.45); 6.0114 (0.83); 5.9920 (0.97); 5.9836 (0.95); 5.9642 (0.85); 5.7568 (8.44); 5.4535 (0.41); 5.2440 (0.44); 52016 (1.77); 5.1623 (1.87); 5.1199 (0.47); 4.3671 (0.48); 4.3343 (0.51); 4.0382 (0.60); 4.0204 (0.64); 4.0007 (1.22); 3.9726 (1.20); 3.9572 (1.54); 3.9293 (0.92); 3.5563 (16.00); 3.4035 (0.36); 3.3840 (0.44); 3.3746 (0.80); 3.3658 (1.42); 3.3554 (0.36); 3.3464 (1.40); 3.3363 (0.36); 3.3234 (15.83); 3.3028 (1.17); 3.2691 (0.36); 3.2389 (0.65); 3.2110 (0.38); 2.8380 (0.35); 2.8099 (0.62); 2.71802 (0.35); 2.5107 (5.56); 2.5063 (11.36); 2.5018 (15.00); 2.4972 (10.66); 2.4928 (5.02); 2.1934 (1.02); 2.1617 (12.09); 2.1146 (0.47); 2.0840 (0.97); 2.0551 (0.54); 1.9890 (2.61); 1.7818 (0.39); 1.7740 (0.45); 1.7512 (0.42); 1.7428 (0.40); 1.5656 (0.39); 1.5563 (0.43); 1.5352 (0.41); 1.5261 (0.39); 1.1906 (2.44); 1.1735 (2.81); 1.1569 (0.71); -0.0002 (1.85

Pr. I-74, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0491 (5.26); 8.0138 (2.33); 7.5173 (1.08); 7.4994 (1.55); 7.4921 (0.35); 7.4713 (0.79); 7.4669 (0.98); 7.558 (3.25); 7.4512 (3.79); 7.4361 (0.71); 7.4277 (1.35); 7.4219 (0.86); 7.4096 (0.99); 7.4033 (0.73); 7.3939 (0.48); 7.3875 (0.40); 7.0479 (1.56); 7.0288 (1.90); 6.9952 (2.19); 6.8574 (1.25); 6.8406 (1.04); 6.0089 (0.87); 5.9894 (1.01); 5.9810 (1.03); 5.9615 (0.89); 5.7548 (5.931); 4.1712 (1.21); 4.1381 (1.29); 4.0378 (0.52); 4.0200 (0.51); 4.0008 (0.96); 3.9726 (0.98); 3.9572 (1.11); 3.9292 (0.93); 3.5536 (16.00); 3.5176 (0.82); 3.3677 (2.21); 3.3368 (310.39); 3.3328 (319.11); 3.0032 (0.86); 2.9732 (1.58); 2.9441 (0.90); 2.6753 (0.42); 2.6710 (0.59); 2.6666 (0.47); 2.5063 (62.20); 2.5019 (85.08); 2.4975 (65.93); 2.3330 (0.43); 2.3285 (0.59); 2.3242 (0.47); 22324 (9.61); 2.1072 (9.65); 2.0734 (1.36); 2.0481 (1.20); 1.9885 (2.10); 1.6939 (0.34); 1.6845 (0.43); 1.6627 (0.90); 1.6551 (1.04); 1.6327 (0.93); 1.6241 (0.89); 1.6033 (0.36); 1.2347 (0.54); 1.1923 (0.58); 1.1745 (1.12); 1.1567 (0.56); -0.0002 (2.39

Pr. I-75, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 7.9863 (3.90); 7.9519 (1.87); 74777 (0.78); 7.4570 (1.72); 7.4364 (1.14); 7.3131 (0.63); 7.2512 (1.41); 7.2308 (2.20); 7.2096 (0.97); 71798 (1.48); 7.1668 (0.72); 7.0466 (0.72); 7.0307 (1.68); 6.9072 (1.38); 6.8950 (0.84); 6.2339 (0.58); 6.2093 (0.75); 6.2031 (0.72); 6.1784 (0.62); 5.4601 (0.33); 5.4176 (1.11); 5.3759 (1.11); 5.3335 (0.34); 5.1488 (5.46); 4.3615 (0.32); 4.3286 (0.34); 3.9551 (0.33); 3.8097 (0.49); 3.7787 (0.60); 3.767 (0.78); 3.7364 (0.63); 3.5632 (0.74); 3.5385 (0.70); 3.5208 (0.55); 3.4963 (0.54); 3.4037 (0.43); 3.3947 (0.70); 3.3849 (0.50); 3.3652 (0.94); 3.3341 (223.11); 3.3109 (3.74); 3.2785 (0.65); 3.2487 (0.38); 2.8904 (16.00); 2.8532 (0.42); 2.7306 (12.60); 2.5244 (0.59); 2.5196 (0.98); 2.5110 (15.64); 2.5065 (32.65); 2.5019 (44.55); 2.4974 (33.38); 2.4929 (16.99); 2.1146 (0.58); 2.0733 0.63); -0.0002 (4.67

Pr. I-76, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0230 (9.77); 8.0081 (0.76); 7.9517 (0.58); 7.4166 (0.80); 7.4124 (0.98); 7.3922 (1.71); 7.3775 (2.75); 7.3734 (2.96); 7.3583 (2.18); 7.2157 (2.73); 7.1963 (2.27); 7.1143 (1.43); 7.0954 (2.36); 7.0769 (1.10); 6.9977 (1.66); 6.8605 (4.09); 6.7234 (1.82); 6.2926 (3.75); 5.9010 (1.19); 5.8831 (1.36); 5.8734 (1.33); 5.8554 (1.22); 5.7557 (6.03); 5.2555 (0.90); 52412 (13.80); 52131 (2.76); 5.1679 (2.56); 5.1251 (0.77); 4.3813 (0.70); 4.3473 (0.77); 4.0377 (0.44); 4.0199 (0.55); 4.0021 (0.682); 3.9677 (0.74); 3.9171 (1.29); 3.8892 (1.47); 3.8741 (1.70); 3.8463 (1.44); 3.3970 (0.63); 3.3875 (0.51); 3.3781 (0.83); 3.3681 (1.43); 3.9586 (1.18); 3.3481 (1.60); 3.3240 (944.69); 3.3022 (5.08); 3.2898 (3.937); 3.2718 (2.25); 3.2469 (2.38); 3.2288 (1.73); 2.8900 (4.95); 2.8488 (0.57); 2.8209 (0.91); 2.7902 (0.51); 2.7301 (3.96); 2.6793 (0.48); 2.6749 (1.09); 2.6703 (1.55); 2.6657 (1.12); 2.6612 (0.52); 2.5406 (0.71); 2.5237 (2.48); 2.5189 (4.21); 2.5103 (76.92); 2.5057 (164.96); 2.5011 (231.48); 2.4966 (173.46); 2.4920 (84.86); 2.3371 (0.59); 2.3325 (1.16); 2.3280 (1.60); 2.3234 (1.18); 2.3189 (0.61); 2.1838 (16.00); 2.1703 (0.87); 21247 (0.79); 2.0919 (1.42); 2.0736 (2.30); 2.0587 (0.81); 1.9884 (2.09); 1.7893 (0.58); 1.7813 (0.64); 1.7597 (0.66); 1.5647 (0.58); 1.5546 (0.64); 1.5331 (0.62); 1.5248 (0.59); 1.2582 (0.33); 1.2350 0.67); 1.1922 (0.56); 1.1744 (1.10); 1.1566 (0.54); 0.0080 (0.45); -0.0002 (15.58); -0.0085 (0.62

Pr. I-77, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.4369 (0.47); 8.0448 (10.27); 8.0361 (0.62); 7.5365 (1.69); 7.5168 (4.07); 7.4970 (2.85); 7.4110 (2.50); 7.3914 (1.84); 7.3522 (2.05); 7.3470 (3.37); 7.3428 (2.52); 7.3139 (2.60); 7.3108 (3.28); 7.2963 (1.74); 7.2941 (1.67); 7.2902 (1.42); 71777 (4.10); 7.1663 (2.52); 7.1578 (0.47); 7.0446 (1.98); 7.0305 (4.84); 7.0215 (0.83); 6.9059 (4.48); 6.8947 (2.46); 6.8857 (0.46); 5.8272 (1.36); 5.8075 (1.63); 5.8002 (1.61); 5.7802 (1.47); 5.4573 (0.91); 5.4145 (3.20); 5.3986 (0.46); 5.3734 (3.23); 5.3306 (0.95); 4.3636 (0.91); 4.3304 (1.00); 4.0556 (0.44); 4.0377 (1.29); 4.0199 (1.31); 4.0021 (0.55); 3.9823 (0.84); 3.9509 (2.39); 3.9235 (1.87); 3.9078 (2.12); 3.8805 (1.72); 3.5696 (2.17); 3.5513 (7.25); 3.5329 (7.41); 3.5146 (2.34); 3.4252 (2.17); 3.4157 (0.91); 3.4053 (2.40); 3.3964 (1.08); 3.9821 (2.49); 3.3621 (2.62); 3.3248 (567.54); 3.2768 (1.59); 3.2641 (1.79); 3.2427 (0.97); 3.2365 (0.96); 3.2266 (0.92); 3.2084 (0.39); 2.8655 (0.71); 2.8383 (1.28); 2.8081 (0.73); 2.6792 (0.47); 2.6748 (1.07); 2.6703 (1.54); 2.6658 (1.14); 2.6613 (0.55); 2.5406 (0.71); 2.5237 (3.00); 2.5187 (5.09); 2.5102 (79.36); 2.5057 (165.28); 2.5012 (225.50); 2.4966 (168.65); 2.4921 (85.36); 2.3371 (0.60); 2.3325 (1.20); 2.3280 (1.63); 2.3233 (1.23); 2.3191 (0.65); 2.1313 (0.91); 2.0992 (1.87); 2.0735 (1.55); 2.0631 (1.11); 1.9884 (5.84); 1.9611 (1.79); 1.8489 (0.37); 1.8407 (0.43); 1.8193 (0.79); 1.8102 (0.86); 1.7882 (0.79); 1.7795 (0.78); 1.7588 (0.38); 1.6138 (0.34); 1.6047 (0.41); 1.5847 (0.78); 1.5749 (0.86); 1.5539 (0.86); 1.5450 (0.79); 1.5242 (0.40); 1.5142 (0.36); 1.3919 (7.48); 1.3736 (16.00); 1.93553 (7.44); 1.3373 (0.39); 1.2585 (0.47); 1.2364 (0.80); 1.1922 (1.65); 1.1745 (3.23); 1.1566 (1.58); 1.1092 (0.40); 1.0914 (0.78); 1.0736 (0.39); 1.0122 0.43); 0.9946 (0.81); 0.9768 (0.39); 0.0080 (0.95); -0.0002 (30.52); -0.0085 (1.29

Pr. I-78, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 7.9922 (9.22); 7.9526 (1.69); 7.4805 (1.85); 7.4599 (4.02); 7.4392 (2.72); 7.2550 (2.60); 7.2530 (3.26); 7.2324 (4.91); 7.2108 (2.16); 6.5056 (4.36); 6.2331 (1.34); 6.2085 (1.75); 6.2023 (1.62); 6.1776 (1.41); 5.7631 (6.26); 5.3610 (0.94); 5.3184 (2.64); 52690 (2.63); 5.2268 (0.93); 5.1549 (11.27); 4.3851 (0.70); 4.3514 (0.77); 4.0367 (0.61); 4.0189 (0.63); 4.0010 (0.61); 3.9937 (0.68); 3.9588 (0.73); 3.8108 (1.10); 3.7798 (1.38); 3.7684 (1.75); 3.7376 (1.40); 3.5620 (1.65); 3.537 (1.61); 3.5196 (1.21); 3.4951 (1.24); 3.4189 (0.69); 3.4096 (0.69); 3.3997 (1.16); 3.3899 (2.15); 3.3690 (108.60); 3.3668 (101.36); 33622 (127.26); 3.3560 (125.13); 3.3524 (144.53); 3.3509 (141.27); 3.3055 (0.87); 3.2749 (1.13); 32478 (0.65); 2.8906 (14.82); 2.8479 (0.92); 2.8216 (0.53); 2.7313 (11.33); 2.7303 (11.30); 2.6773 (0.51); 2.6727 (0.72); 2.6681 (0.53); 2.5429 (0.40); 2.5261 (1.32); 2.5213 (2.04); 2.5126 (38.21); 2.5081 (82.76); 2.5036 (111.59); 2.4990 (79.36); 2.4945 (37.44); 2.3348 (0.53); 2.3303 (0.75); 2.3257 (0.55); 2.2078 (16.00); 2.1950 (0.87); 2.1503 (0.65); 2.1147 (1.35); 2.0850 (0.76); 2.0775 (1.15); 1.9902 (2.88); 1.9096 (0.35); 1.8345 (0.59); 1.8255 (0.64); 1.8034 (0.59); 1.7954 (0.57); 1.5943 (0.56); 1.5849 (0.64); 1.5627 (0.60); 1.5545 (0.58); 1.1920 (0.78); 1.1742 (1.53); 1.1564 (0.78); 0.0080 (0.48); -0.0002 (18.29); -0.0085 (0.67

Pr. I-79, Solvent: dmeoo-ab, spectrometer: 399.95 MG 8.0501 (6.22); 7.6722 (0.47); 7.6588 (0.52); 7.6498 (0.87); 7.6366 (0.89); 7.6274 (0.56); 7.6141 (0.49); 7.3136 (0.59); 7.3093 (0.62); 7.2895 (1.10); 7.2857 (1.12); 7.2660 (0.58); 7.2619 (0.57); 6.4988 (3.07); 6.0593 (0.78); 6.0384 (0.94); 6.0291 (0.90); 6.0080 (0.81); 5.7568 (0.57); 5.3549 (0.61); 5.9123 (1.89); 5.2635 (1.86); 5.2208 (0.60); 4.3938 (0.51); 4.3613 (0.54); 4.0556 (1.02); 4.0378 (3.13); 4.0200 (3.19); 4.0022 (1.43); 3.9797 (0.74); 3.9623 (0.56); 3.9493 (0.88); 3.9359 (0.84); 3.9055 (0.71); 3.6234 (0.84); 3.6023 (0.84); 3.5797 (0.68); 3.5587 (0.70); 3.5167 (16.00); 3.4273 (0.37); 3.4081 (0.43); 3.3986 (0.77); 3.3890 (0.45); 3.3699 (0.41); 3.3209 (30.11); 3.2972 (1.38); 3.2726 (0.69); 3.2441 (0.40); 2.8723 (0.36); 2.8419 (0.65); 2.8149 (0.38); 2.5237 (0.37); 2.5103 (11.06); 2.5058 (23.14); 2.5013 (31.00); 2.4967 (22.17); 2.4923 (10.49); 2.2098 (11.51); 2.1947 (0.40); 2.1486 (0.51); 2.1199 (0.97); 2.0884 (0.53); 1.9887 (13.75); 1.8311 (0.41); 1.8050 (0.98); 1.5885 (0.41); 1.5665 (0.38); 1.5582 0.37); 1.1922 (3.85); 1.1744 (7.65); 1.1566 (3.78); -0.0002 (3.14

Pr. I-80, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0388 (9.66); 7.4465 (0.67); 7.4336 (0.75); 7.4231 (1.48); 7.4104 (1.47); 7.3997 (0.87); 7.3872 (0.77); 7.3151 (1.54); 7.2340 (0.98); 7.2295 (1.00); 7.2096 (1.71); 7.2059 (1.67); 7.1818 (4.41); 7.1682 (1.74); 7.0486 (1.74); 7.0321 (4.06); 6.9075 (3.56); 6.8963 (2.00); 6.0337 (1.22); 6.0127 (1.45); 6.0036 (1.39); 5.9824 (1.28); 5.7569 (9.75); 54631 (0.82); 54204 (2.79); 5.3791 (2.76); 5.3366 (0.82); 5.2533 (16.00); 4.3723 (0.79); 4.3392 (0.83); 4.0556 (0.60); 4.0378 (1.79); 4.0200 (1.85); 4.0021 (0.97); 3.9910 (0.74); 3.9546 (1.62); 3.9239 (1.04); 3.9109 (1.25); 3.8808 (1.08); 3.5951 (1.27); 3.5739 (1.29); 3.5516 (1.04); 3.5307 (1.03); 3.4310 (0.56); 3.4213 (0.38); 3.4115 (0.65); 3.4023 (1.16); 3.3931 (0.66); 3.3832 (0.42); 3.3735 (0.60); 3.3206 (38.64); 3.2970 (1.00); 3.2730 (1.05); 3.2434 (0.60); 2.8716 (0.54); 2.8418 (1.00); 2.8149 (0.59); 2.6703 (0.34); 2.5647 (1.08); 2.5237 (0.59); 2.5102 (19.61); 2.5058 (40.56); 2.5013 (54.06); 2.4967 (38.60); 2.4923 (18.40); 2.3280 (0.38); 2.1485 (0.74); 2.1165 (1.47); 2.0817 (0.83); 1.9887 (8.06); 1.8257 (0.70); 1.8006 (0.60); 1.5978 (0.63); 1.5895 (0.69); 1.5683 0.63); 1.5595 (0.61); 1.1923 (2.19); 1.1744 (4.35); 1.1567 (2.14); -0.0002 (1.95

Pr. I-81, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0245 (9.35); 7.4137 (4.81); 7.3962 (3.00); 7.3920 (5.26); 7.3847 (0.64); 7.3116 (1.49); 7.1784 (3.35); 7.1663 (1.63); 7.1031 (6.16); 7.0979 (1.79); 7.0859 (2.83); 7.0811 (5.19); 7.0737 (0.58); 7.0452 (1.66); 7.0303 (3.88); 6.9081 (3.51); 6.8945 (1.90); 5.7533 (0.62); 5.7273 (1.22); 5.7058 (1.78); 5.7005 (1.47); 5.6792 (1.29); 54590 (0.83); 5.4164 (2.76); 5.3738 (2.76); 5.3312 (0.84); 5.1779 (16.00); 4.366 (0.88); 4.3337 (0.92); 3.9849 (0.82); 3.9516 (0.90); 3.8749 (1.29); 3.8477 (1.52); 3.8318 (1.74); 3.8048 (1.48); 3.4915 (0.34); 3.4565 (0.43); 3.4275 (1.05); 3.4175 (1.58); 3.4025 (3.79); 3.3809 (7.09); 3.3484 (821.81); 3.3465 (916.05); 3.2699 (2.18); 3.2401 (1.18); 3.2005 (0.33); 3.1836 (0.34); 2.8703 (0.64); 2.8431 (1.18); 2.8115 (0.69); 2.6765 (0.86); 2.6720 (1.01); 2.6673 (0.70); 2.5421 (0.63); 2.5251 (2.47); 2.5118 (68.16); 2.5074 (120.20); 2.5028 (140.10); 2.4982 (93.78); 2.4937 (39.72); 2.3341 (0.80); 2.3296 (0.97); 2.3250 (0.64); 2.1389 (0.78); 2.1042 (1.63); 2.0861 (0.83); 2.0729 (10.70); 1.8426 (0.32); 1.8204 (0.71); 1.8137 (0.72); 1.7909 (0.71); 1.6091 (0.32); 1.5876 (0.69); 1.5799 (0.72); 1.5578 0.70); 1.5489 (0.65); 1.3975 (0.44); 1.2352 (0.63); -0.0002 (6.19

Pr. I-82, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0454 (3.03); 8.0182 (16.00); 7.4601 (2.54); 7.4558 (3.24); 74411 (3.31); 7.4368 (4.32); 7.4323 (2.69); 7.4281 (2.28); 7.4132 (3.48); 7.4088 (3.33); 7.3937 (2.93); 7.3893 (2.79); 7.3200 (3.11); 7.3171 (3.07); 7.3109 (3.32); 7.3012 (4.51); 7.2983 (3.95); 7.2824 (1.87); 7.2796 (1.53); 7.2033 (4.24); 7,2006 (4,17); 7.1940 (1.42); 7.1910 (1.37); 7.1832 (4.32); 7.1778 (7.48); 7.1712 (1.67); 7.1665 (3.53); 7.1268 (0.70); 7.1097 (2.85); 7.0924 (2.92); 7.0880 (0.86); 7.0708 (3.08); 7.0535 (3.26); 7.0445 (3.40); 7.0362 (1.42); 7.0305 (7.86); 6.9061 (6.21); 6.8947 (3.96); 6.0605 (3.03); 6.0561 (3.07); 6.0522 (1.10); 6.0216 (2.83); 6.0173 (2.80); 5.9757 (0.37); 5.9502 (0.51); 5.9329 (0.59); 5.9072 (0.39); 5.7910 (0.45); 5.7710 (0.53); 5.7581 (2.14); 5.7387 (2.58); 5.7296 (2.46); 5.7099 (2.16); 5.4591 (1.41); 5.4170 (4.58); 5.3715 (4.86); 5.3292 (1.55); 5.2488 (0.62); 5.2444 (0.67); 5.2041 (0.93); 5.2013 (1.03); 5.1785 (0.59); 5.1743 (0.52); 4.3662 (1.39); 4.3336 (1.50); 3.9807 (1.37); 3.9489 (1.50); 3.9010 (0.45); 3.8724 (0.83); 3.8670 (2.20); 3.8578 (0.83); 3.8384 (2.66); 3.8239 (2.98); 3.7954 (2.40); 3.4166 (1.94); 3.4023 (2.08); 3.3997 (1.98); 3.3960 (1.73); 3.3848 (2.42); 3.3748 (1.69); 3.9652 (1.51); 3.3271 (381.58); 3.3214 (262.52); 3.2965 (7.17); 3.2723 (3.89); 3.2647 (2.48); 3.2530 (3.30); 3.2353 (1.28); 3.2269 (1.33); 3.2071 (0.66); 2.8630 (0.98); 2.8360 (1.82); 2.8032 (1.00); 2.6792 (0.58); 2.6750 (1.24); 2.6703 (1.77); 2.6658 (1.30); 2.65612 (0.63); 2.5406 (0.89); 2.5237 (4.52); 2.5188 (7.69); 2.5104 (93.07); 2.5059 (191.83); 2.5013 (257.12); 2.4967 (186.57); 2.4922 (93.79); 2.3326 (1.29); 2.3281 (1.81); 2.3234 (1.37); 2.1269 (1.30); 2.0940 (2.83); 2.0735 (15.37); 2.0603 (1.75); 1.8660 (10.28); 1.8617 (10.50); 1.8487 (10.70); 1.8445 (10.87); 1.8120 (1.20); 1.8050 (1.25); 1.7788 (1.14); 1.7530 (0.46); 1.6076 (0.48); 1.5960 (0.52); 1.5758 (1.15); 1.5665 (1.29); 1.5466 (1.14); 1.5372 (1.15); 1.5160 (0.46); 1.5068 (0.42); 1.2355 (0.72); 0.0080 (1.21); -0.0002 (34.84); -0.0085 (1.55

Pr. I-83, Solvent: DMOSO-ab, spectrometer: 399.95 MHz 8.4366 (0.64); 8.3796 (0.36); 8.0445 (16.00); 8.0359 (0.71); 7.5374 (2.63); 7.5178 (6.35); 7.4980 (4.57); 7.4187 (4.02); 7.3988 (3.03); 7.3851 (3.74); 7.3800 (5.54); 7.3389 (3.17); 7.3351 (2.59); 7.3329 (2.51); 7.3186 (2.61); 7.3112 (3.79); 7.1771 (6.56); 7.1658 (3.91); 7.0439 (3.17); 7.0300 (7.63); 7.0212 (1.14); 6.9062 (7.02); 6.8941 (3.79); 6.8856 (0.59); 5.8328 (2.20); 5.81391 (2.61); 5.8056 (2.59); 5.7859 (2.31); 5.4563 (1.46); 5.4138 (5.06); 5.3725 (5.13); 5.3295 (1.52); 4.3618 (1.44); 4.3295 (1.57); 4.0555 (0.94); 4.0377 (2.89); 4.0199 (2.95); 4.0021 (1.14); 3.9809 (1.36); 3.9539 (3.50); 3.9267 (3.03); 3.9109 (3.33); 3.8836 (2.70); 3.4169 (3.79); 3.3972 (4.27); 3.3853 (2.82); 3.3739 (4.60); 3.3539 (7.40); 3.3284 (1199.72); 3.3270 (1286.87); 3.3038 (22.05); 3.2651 (3.07); 3.2357 (1.59); 3.1127 (0.95); 3.1009 (1.92); 3.0928 (1.98); 3.0893 (1.42); 3.0811 (3.76); 3.0728 (1.33); 3.0694 (2.17); 3.0613 (2.00); 3.0496 (1.07); 2.8655 (1.14); 2.8380 (2.01); 2.8083 (1.14); 2.6750 (1.59); 2.6705 (2.31); 2.6660 (1.71); 2.5408 (1.17); 2.5237 (4.85); 2.5104 (118.36); 2.5059 (246.12); 2.5014 (336.38); 2.4969 (252.95); 2.4924 (129.01); 2.3326 (1.74); 2.3282 (2.41); 2.3236 (1.83); 2.1296 (1.41); 2.0963 (2.90); 2.0734 (4.02); 2.0614 (1.74); 2.0270 (0.34); 2.0089 (0.45); 1.9884 (12.80); 1.8374 (0.65); 1.8163 (1.22); 1.8075 (1.32); 1.7853 (1.23); 1.7764 (1.14); 1.7557 (0.54); 1.6038 (0.64); 1.5825 (1.21); 1.5741 (1.33); 1.5523 (1.27); 1.5438 (1.22); 1.5226 (0.60); 1.5123 (0.52); 1.3976 (0.73); 1.2974 (0.41); 1.2581 (0.73); 1.2356 (1.27); 1.1923 (3.68); 1.1858 (1.07); 1.1745 (8.01); 1.1696 (3.88); 1.1632 (5.43); 1.1567 (4.52); 1.1483 (4.62); 1.1434 (5.41); 1.1284 (1.39); 1.1174 (0.57); 1.1060 (0.33); 1.0397 (0.49); 1.0353 (0.47); 1.0279 (0.60); 1.0199 (1.64); 1.0071 (4.82); 1.0001 (5.20); 0.9949 (4.32); 0.9902 (3.59); 0.9795 (1.37); 0.9707 0.58); 0.9596 (0.39); 0.8538 (0.46); 0.0080 (1.22); -0.0002 (40.09); -0.0085 (1.78

Pr. I-84, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0739 (11.05); 7.5265 (1.683); 7.5147 (1.95); 7.5041 (2.26); 7.4922 (2.24); 7.3535 (1.05); 7.3456 (1.35); 7.3337 (1.28); 7.3256 (1.64); 7.3235 (1.61); 7.3148 (1.81); 7.3118 (1.28); 7.3039 (3.25); 7.2964 (1.49); 7.2814 (2.26); 7.2735 (1.47); 7.1817 (3.81); 7.1728 (1.86); 7.0485 (1.85); 7.0368 (4.42); 6.9123 (3.64); 6.9010 (2.15); 6.0032 (1.14); 5.9836 (1.33); 5.9755 (1.34); 5.9558 (1.18); 5.4655 (0.96); 5.4227 (2.86); 5.3781 (2.82); 5.3357 (0.95); 4.3674 (0.84); 4.3342 (0.86); 4.0217 (1.40); 3.9937 (2.00); 3.9784 (2.49); 3.9505 (2.31); 3.4275 (1.98); 3.4170 (0.71); 3.4081 (2.12); 3.3980 (0.81); 3.3844 (2.20); 3.3649 (2.06); 3.3401 (159.03); 3.3162 (3.05); 3.3078 (1.43); 3.2998 (1.59); 3.2962 (1.38); 3.2881 (2.72); 3.2803 (0.85); 3.2764 (1.43); 3.2683 (1.84); 3.2613 (1.22); 3.2568 (1.34); 3.2327 (0.63); 3.2269 (0.51); 2.8591 (0.60); 2.8288 (1.05); 2.8014 (0.59); 2.6764 (0.39); 2.6719 (0.55); 2.6673 (0.42); 2.5253 (1.05); 2.5206 (1.56); 2.5118 (28.91); 2.5074 (62.42); 2.5028 (83.96); 2.4983 (59.93); 2.4938 (28.18); 2.3341 (0.938); 2.3296 (0.53); 2.3249 (0.40); 21277 (0.71); 2.0958 (1.52); 2.0772 (16.00); 2.0641 (0.92); 1.8181 (0.63); 1.8084 (0.70); 1.7869 (0.63); 1.7786 (0.60); 1.5769 (0.64); 1.5666 (0.71); 1.5455 (0.66); 1.5367 (0.65); 1.2881 (0.33); 1.2791 (0.35); 1.2708 (1.44); 1.2628 (2.40); 1.2593 (2.55); 1.2546 (1.78); 1.2516 (1.57); 1.2429 (2.57); 1.2396 (2.60); 1.2355 (2.15); 1.2254 (0.65); 1.2166 (0.58); 1.2131 (0.44); 1.2060 (0.55); 1.1799 (0.48); 1.1728 (0.48); 1.1676 (0.66); 1.1609 (0.57); 1.1545 (0.91); 1.1471 (1.12); 1.1428 (2.55); 1.1352 (1.49); 1.1311 (3.44); 1.1234 (1.40); 1.1195 (1.993; 1.1119 (1.00); 1.1052 (0.83); 1.0989 (0.37); 1.0938 (0.39); 1.0871 (0.33) ; 0.0080 (0.75); -0.0002 (25.82); -0.0085 (0.88

Pr. I-85, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0761 (6.93); 7.4808 (0.35); 7.4660 (1.41); 7.4614 (1.79); 7.4447 (3.75); 7.4361 (1.55); 7.4297 (1.54); 7.4237 (0.47); 7.3309 (1.07); 7.3243 (1.43); 7.3143 (1.52); 7.1814 (2.62); 7.1720 (1.28); 7.0483 (1.27); 7.0360 (3.04); 6.9120 (2.55); 6.9002 (1.47); 6.0131 (1.02); 5.9941 (1.20); 5.9854 (1.22); 5.9662 (1.05); 5.7617 (10.48); 5.4645 (0.65); 5.4219 (2.00); 5.3781 (1.97); 5.3356 (0.64); 4.3675 (0.58); 4.3343 (0.61); 4.0198 (0.98); 3.9918 (1.44); 3.9763 (1.72); 3.9484 (1.65); 3.6513 (16.00); 3.4176 (1.63); 3.4084 (0.39); 3.3986 (1.69); 3.3889 (0.95); 3.3742 (1.39); 3.3487 (44.70); 3.3451 (35.35); 3.3418 (46.84); 3.3184 (3.02); 3.2911 (0.48); 3.2608 (0.77); 3.2316 (0.43); 2.8587 (0.42); 2.8277 (0.73); 2.8010 (0.42); 2.5423 (0.44); 2.5255 (0.36); 2.5208 (0.59); 2.5121 (12.17); 2.5076 (26.69); 2.5030 (36.41); 2.4984 (26.02); 2.4939 (12.23); 2.1298 (0.50); 2.0979 (1.05); 2.0770 (0.62); 2.0627 (0.58); 1.8190 (0.45); 1.8105 (0.50); 1.7883 (0.46); 1.7795 (0.43); 1.5777 (0.46); 1.5681 (0.52); 1.5470 (0.48); 1.5377 (0.46); -0.0002 (5.45

Pr. I-86, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 7.9999 (8.83); 7.5107 (0.76); 7.4940 (0.89); 7.4896 (1.61); 7.4731 (1.61); 7.4686 (1.02); 7.4520 (0.87); 7.0819 (2.33); 7.0606 (2.11); 7.0193 (1.20); 6.9944 (1.40); 6.9724 (1.09); 6.5032 (4.17); 6.0706 (1.02); 6.0485 (1.24); 6.0403 (1.20); 6.0178 (1.07); 5.3607 (0.92); 5.3179 (2.63); 5.2674 (2.56); 5.2179 (10.84); 4.3896 (0.69); 4.3562 (0.73); 4.0547 (1.07); 4.0369 (3.34); 4.0191 (3.37); 4.0012 (1.51); 3.9944 (0.67); 3.9598 (0.71); 3.8411 (0.69); 3.8103 (0.81); 3.8006 (0.96); 3.7980 (1.00); 3.7680 (0.89); 3.6285 (0.36); 3.5284 (1.18); 3.5060 (1.19); 3.4853 (0.92); 3.4630 (0.93); 3.4196 (0.48); 3.4113 (0.38); 3.4005 (0.65); 3.3917 (1.12); 3.3823 (0.73); 3.3418 (264.11); 3.3183 (1.62); 3.3038 (0.81); 3.2727 (0.99); 3.2442 (0.57); 3.2389 (0.49); 2.8902 (2.34); 2.8801 (0.42); 2.8734 (0.52); 2.8435 (0.87); 2.8171 (0.49); 2.7301 (1.84); 2.6762 (0.55); 2.6717 (0.78); 2.6670 (0.58); 2.5420 (0.36); 2.5251 (1.38); 2.5203 (2.06); 2.5116 (39.71); 2.5071 (86.95); 2.5026 (118.66); 2.4980 (85.45); 2.4935 (40.68); 2.3339 (0.57); 2.3293 (0.79); 2.3248 (0.58); 2.2076 (16.00); 2.1915 (0.40); 2.1496 (0.69); 2.1184 (1.31); 2.0767 (1.74); 1.9898 (14.73); 1.8346 (0.55); 1.8265 (0.67); 1.8043 (0.55); 1.7960 (0.50); 1.5925 (0.55); 1.5841 (0.62); 1.5627 (0.57); 1.5535 (0.56); 1.2348 (0.34); 1.1920 (4.09); 1.1742 (8.14); 1.1564 (4.01); 0.0080 (0.60); -0.0002 (22.73); -0.0085 (0.84

Pr. I-87, Solvent: DMOSO-ab, spectrometer: 399.95 MHz 11.5325 (0.58); 8.0721 (11.84); 7.7465 (0.92); 7.3182 (1.70); 7.2958 (0.33); 7.2424 (0.46); 7.1850 (4.06); 7.1742 (2.12); 7.0519 (1.94); 7.0382 (4.90); 6.9639 (2.57); 6.9595 (3.09); 6.9572 (3.18); 6.9528 (2.81); 6.9138 (4.13); 6.9025 (2.39); 6.2256 (1.97); 6.2217 (2.16); 6.2168 (2.36); 6.2129 (2.28); 6.0328 (2.63); 6.0254 (3.11); 6.0241 (3.10); 6.0167 (2.46); 5.9000 (1.91); 5.8760 (2.66); 5.8512 (1.37); 5.7615 (4.60); 5.4706 (0.96); 5.4280 (2.90); 5.3818 (3.11); 5.3388 (1.06); 4.3752 (0.89); 4.3421 (1.01); 4.3259 (0.43); 4.3057 (1.56); 4.3023 (1.54); 4.2895 (3.01); 4.2850 (3.04); 4.2734 (1.43); 42679 (1.53); 42188 (0.935); 4.0547 (1.11); 4.0369 (3.43); 4.0191 (3.51); 4.0013 (1.66); 3.9925 (0.84); 3.9588 (0.91); 3.7461 (0.47); 3.7207 (0.52); 3.7033 (2.72); 3.6885 (2.49); 3.6780 (2.47); 3.6654 (2.55); 3.6459 (0.53); 3.6227 (0.41); 3.4306 (0.59); 3.4213 (0.46); 3.4109 (0.75); 3.4018 (1.33); 3.3923 (0.92); 3.3839 (0.68); 3.3620 (1.99); 3.3452 (610.80); 3.93211 (5.69); 3.3095 (1.35); 3.3030 (1.21); 3.2727 (1.40); 3.2429 (0.79); 3.0290 (3.00); 3.0123 (5.99); 2.9954 (2.43); 2.9008 (0.48); 2.8706 (0.68); 2.8392 (1.16); 2.8125 (0.66); 2.6763 (0.70); 2.6717 (0.99); 2.6671 (0.74); 2.6630 (0.34); 2.5420 (0.52); 2.5252 (1.67); 2.5205 (2.56); 2.5118 (50.41); 2.5073 (111.21); 2.5027 (151.96); 2.4981 (109.17); 2.4936 (51.47); 2.3385 (0.36); 2.3340 (0.76); 2.3294 (1.02); 2.3248 (0.77); 2.1494 (0.91); 2.1139 (1.64); 2.0765 (2.12); 1.9898 (16.00); 1.8528 (0.36); 1.8263 (0.78); 1.7965 (0.66); 1.6161 (0.36); 1.5931 (0.69); 1.5848 (0.74); 1.5643 (0.66); 1.5545 (0.64); 1.2348 (0.43); 1.1920 (4.40); 1.1741 (8.83); 1.1563 (4.27); 0.0080 (0.81); -0.0002 (29.82); -0.0085 (0.94

Pr. I-88, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0296 (6.12); 7.4048 (1.35); 7.3840 (2.95); 7.3632 (1.80); 7.3157 (1.18); 7.1824 (2.70); 7.1698 (1.42); 7.1375 (2.21); 7.1173 (1.86); 7.0493 (1.31); 7.0338 (2.96); 6.9775 (2.27); 6.9570 (2.15); 6.9085 (3.03); 6.8982 (1.68); 5.7570 (0.53); 5.4640 (0.70); 5.4213 (2.29); 5.3775 (2.31); 5.3349 (0.74); 4.3778 (0.68); 4.3450 (0.72); 3.9903 (0.63); 3.9553 (0.71); 3.9050 (15.64); 3.8541 (0.87); 3.7644 (1.76); 3.7199 (2.79); 3.5829 (2.54); 3.5384 (1.76); 3.4396 (17.36); 3.4155 (0.51); 3.4011 (1.05); 3.3867 (0.94); 3.3774 (0.57); 3.3580 (0.62); 3.3485 (0.85); 3.3208 (237.09); 3.2970 (4.84); 3.2627 (1.18); 3.2337 (0.62); 2.8577 (0.48); 2.8279 (0.88); 2.7993 (0.50); 2.6746 (0.98); 2.6703 (1.935); 2.5402 (0.44); 2.5055 (148.71); 2.5012 (195.33); 2.4969 (143.13); 2.3322 (1.11); 2.3279 (1.47); 23236 (1.11); 2.1331 (0.68); 21001 (1.36); 2.0678 (0.78); 1.8395 (0.35); 1.8110 (0.65); 1.7886 (0.61); 1.5917 (12.41); 1.5519 (0.62); 1.4720 (0.69); 1.3976 (16.00); 0.1460 (0.56); 0.0078 (4.59); -0.0002 (118.21); -0.0083 (4.81); - 0.1497 (0.59

Pr. I-90, Solvent: СсОоЗсМ, spectrometer: 399.95 MHz 7.7019 (2.44); 7.6969 (2.94); 7.5087 (0.69); 7.5007 (0.56); 7.4918 (0.92); 7.4835 (0.79); 7.164 (0.40); 7.4094 (0.34); 7.4044 (0.75); 7.3939 (1.07); 7.3847 (0.70); 7.3751 (1.43); 7.3671 (2.97); 7.3593 (1.83); 7.3488 (1.16); 7.3459 (0.95); 6.3904 (2.70); 6.0519 (0.60); 6.0439 (0.48); 6.0298 (0.71); 6.0240 (0.85); 6.0163 (0.56); 6.0025 (0.63); 5.9939 (0.49); 5.4468 (0.56); 5.1259 (0.52); 5.0839 (2.60); 5.0532 (2.55); 5.0112 (0.50); 4.4967 (0.52); 4.4634 (0.56); 4.2548 (0.80); 42211 (1.10); 4.1499 (3.60); 4.0502 (1.14); 4.0164 (0.83); 3.9477 (0.51); 3.9287 (0.84); 3.9225 (0.89); 3.9133 (0.59); 3.9014 (0.96); 3.8948 (0.63); 3.8855 (0.87); 3.8795 (0.69); 3.8580 (0.79); 3.8518 (0.63); 3.7842 (1.48); 3.7734 (1.72); 3.7669 (1.72); 3.7561 (2.19); 3.7466 (0.70); 3.7402 (0.71); 3.7369 (0.72); 3.3656 (1.40); 3.3499 (0.66); 3.3423 (1.86); 33328 (16.00); 3.3221 (1.69); 3.3117 (1.00); 3.3003 (1.931); 3.2823 (0.76); 3.2532 (0.42); 3.2467 (0.39); 3.1063 (0.34); 3.0901 (0.64); 3.0719 (0.95); 3.0565 (0.99); 3.0410 (0.43); 3.037 (0.78); 2.9019 (0.44); 2.8914 (0.82); 2.8806 (0.74); 2.8682 (0.41); 2.8573 (0.84); 2.8467 (0.97); 2.8363 (0.46); 2.8255 (0.68); 2.8146 (0.66); 2.7917 (0.51); 2.2253 (12.73); 22101 (0.58); 2.2028 (0.50); 2.1513 (10.09); 2.1474 (8.73); 2.1194 (0.64); 1.9635 (0.87); 1.9572 (1.04); 1.9516 (7.58); 1.9455 (14.12); 1.9393 (19.51); 1.9331 (13.37); 1.9269 (6.90); 1.8723 (0.50); 1.8625 (0.51); 1.8413 (0.46); 1.8310 (0.46); 1.7055 (0.49); 1.6953 (0.51); 1.6742 (0.47); 1.6641 (0.46); -0.0002 (5.32

Pr. I-91, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 7.9819 (4.47); 7.3970 (2.79); 7.3076 (3.08); 7.1769 (1.683); 7.1674 (0.91); 7.0438 (0.89); 7.0313 (2.04); 6.9065 (1.86); 6.8956 (1.07); 5.4550 (0.43); 5.4132 (1.42); 553711 (1.40); 5.3283 (0.45); 4.6173 (0.39); 4.3579 (0.41); 4.3256 (0.42); 4.0554 (0.40); 4.0377 (1.24); 4.0199 (1.25); 4.0021 (0.44); 3.9774 (0.39); 3.9437 (0.42); 3.7138 (0.60); 3.7098 (0.46); 3.7016 (0.75); 3.6998 (0.77); 3.6780 (1.64); 3.6699 (0.56); 3.6658 (0.78); 3.6347 (1.82); 3.5940 (12.37); 3.5644 (1.92); 3.5210 (1.13); 3.5092 (0.34); 3.4959 (0.57); 3.4839 (0.52); 3.4722 (0.81); 3.4611 (0.68); 3.3800 (0.36); 3.3711 (0.60); 3.3621 (0.38); 3.3489 (7.43); 3.3194 (28.50); 3.2956 (3.47); 3.2579 (0.56); 2.8272 (0.52); 2.6748 (0.33); 2.6702 (0.47); 2.6657 (0.34); 2.5234 (0.94); 2.5101 (25.31); 2.5057 (52.15); 2.5012 (69.37); 2.4966 (49.70); 2.4922 (23.79); 2.3324 (0.36); 2.3279 (0.49); 2.3233 (0.37); 22300 (16.00); 2.1165 (0.40); 2.0862 (0.80); 2.0509 (0.44); 1.9886 (5.38); 1.7976 (0.36); 1.7892 (0.38); 1.7666 (0.36); 1.7573 (0.33); 1.6913 (7.59); 1.5583 (0.43); 1.5299 (0.34); 1.1922 (1.49); 1.1744 (2.953; 1.1566 (1.46); 0.0080 (1.63); -0.0002 48.67); -0.0085 (1.66

Pr. I-92, Solvent: dmeoo-ab, spectrometer: 399.95 MG 8.0166 (5.74); 7.3155 (1.02); 7.1823 (2.40); 7.1697 (1.20); 7.0492 (1.17); 7.0337 (2.71); 6.9082 (2.49); 6.8979 (1.47); 6.6863 (2.42); 6.6801 (2.65); 6.4899 (3.00); 6.4837 (2.94); 5.7569 (0.77); 5.4635 (0.57); 5.4209 (1.87); 5.37 74 (1.89); 5.3350 (0.61); 4.6169 (0.46); 4.37 74 (0.54); 4.3435 (0.58); 4.0376 (0.33); 4.0198 (0.36); 3.9872 (0.49); 3.9476 (0.83); 3.8876 (13.43); 3.7912 (16.00); 3.7798 (0.59); 3.7181 (0.38); 3.7135 (0.85); 3.7062 (1.59); 3.7018 (1.19); 3.6998 (1.18); 3.6798 (1.03); 3.67 79 (1.06); 3.6698 (0.73); 3.6618 (2.56); 3.6550 (0.54); 3.6501 (0.34); 3.5350 (2.14); 3.5094 (0.42); 3.4955 (0.89); 3.4907 (1.64); 3.4840 (0.78); 3.4720 (1.03); 3.4610 (0.88); 3.4496 (0.36); 3.4442 (0.50); 3.4330 (15.26); 3.4138 (0.54); 3.4041 (0.34); 3.3950 (0.61); 3.3841 (0.82); 3.3750 (0.49); 3.3552 (0.47); 3.3489 (1.77); 3.3192 (34.89); 3.2956 (4.23); 3.2623 (0.80); 3.2329 (0.44); 2.8899 (0.71); 2.8563 (0.39); 2.8261 (0.69); 2.7989 (0.39); 2.7302 (0.56); 2.6746 (0.37); 2.6701 (0.52); 2.6656 (0.39); 2.5233 (0.97); 2.5099 (28.08); 2.5056 (59.27); 2.5010 (80.44); 2.4965 (58.62); 24922 (28.66); 2.3323 (0.44); 2.3278 (0.60); 2.3234 (0.45); 2.1350 (0.51); 2.1001 (1.06); 2.0653 (0.61); 1.9885 (1.53); 1.8169 (0.47); 1.8092 (0.50); 1.7671 (0.48); 1.6137 (0.42); 1.5579 (9.81); 1.3974 (0.38); 1.2352 (0.50); 1.1921 (0.43); 1.1 744 (0.84); 1.1565 (0.43); 0.0080 (1.71); -0.0002 (52.18); -0.0085 (1.79

Pr. I-93, Solvent: СсОоЗсМ, spectrometer: 399.95 MHz 7.7017 (16.00); 7.6212 (0.38); 7.4925 (2.89); 7.4730 (4.87); 7.4118 (4.06); 7.3930 (9.89); 7.3750 (3.22); 7.3707 (1.78); 7.3594 (4.03); 7.3555 (3.89); 7.3427 (1.87); 7.3375 (3.71); 7.3227 (1.21); 7.3192 (1.06); 6.4212 (8.33); 6.0495 (0.91); 6.0342 (3.56); 6.0228 (1.57); 6.0119 (3.88); 6.0059 (4.41); 5.9924 (2.32); 5.9843 (3.39); 5.9799 (1.95); 5.9663 (2.17); 5.9524 (1.08); 5.3490 (1.35); 5.3448 (3.42); 5.3405 (3.50); 5.3363 (1.43); 5.3058 (1.21); 5.3017 (3.03); 5.2973 (3.08); 5.2931 (1.27); 52229 (3.20); 5.2187 (2.98); 5.1967 (3.08); 5.1926 (2.85); 5.1566 (1.60); 5.1144 (8.27); 5.0851 (8.34); 5.0642 (0.67); 5.0429 (1.52); 4.67391 (4.96); 4.6439 (8.55); 4.5708 (8.84); 4.5415 (5.09); 4.5136 (1.57); 4.4793 (1.68); 4.1128 (1.37); 4.0950 (4.23); 4.0772 (4.12); 4.0661 (2.85); 4.0622 (6.54); 4.0587 (7.49); 4.0540 (3.71); 4.0484 (6.30); 4.0447 (6.23); 4.0408 (2.77); 4.0261 (0.57); 4.0123 (0.37); 3.9764 (1.52); 3.9418 (1.77); 3.9307 (4.56); 3.9027 (3.89); 3.8875 (4.47); 3.8596 (4.23); 3.4058 (0.73); 3.3962 (1.48); 3.3864 (0.93); 3.37 71 (1.63); 3.3674 (3.05); 3.357 7 (1.77); 3.3481 (2.14); 3.3393 (2.58); 3.3290 (1.17); 3.3192 (5.71); 3.9120 (2.46); 3.2982 (4.61); 3.2829 (1.51); 3.2762 (5.04); 3.2551 (3.87); 2.9168 (1.12); 2.9102 (1.24); 2.8790 (2.12); 2.8528 (1.30); 2.8460 (1.22); 2.3946 (1252.19); 2.3906 (1139.56); 2.3890 (1127.59); 2.2514 (39.92); 22375 (3.51); 2.1877 (3.12); 2.1492 (2.38); 2.1437 (2.41); 2.1373 (2.02); 2.1311 (1.33); 2.0876 (0.69); 2.0001 (17.30); 1.9939 (6.22); 1.9877 (4.47); 1.9819 (37.32); 1.9758 (69.86); 1.9696 (97.74); 1.9634 (67.50); 1.9572 (35.18); 1.9261 (1.11); 1.9158 (1.07); 1.8962 (1.75); 1.8861 (1.80); 1.8639 (1.59); 1.8551 (1.59); 1.8342 (0.81); 1.8242 (0.77); 1.8105 (0.50); 1.8042 (0.66); 1.7980 (0.81); 1.7918 (0.64); 1.7858 (0.47); 1.7654 (0.84); 1.7550 (0.93); 1.7350 (1.63); 1.7249 (1.68); 1.7038 (1.54); 1.6938 (1.54); 1.6739 (0.79); 1.6630 (0.71); 1.3084 (0.35); 1.2468 (4.51); 1.2290 (8.85); 1.2112 (4.42

Pr. I-94, Solvent: DMOSO-ab, spectrometer: 399.95 MHz 8.0020 (16.00); 7.4001 (3.66); 7.3940 (2.68); 7.3870 (4.54); 7.3819 (7.38); 7.3752 (7.80); 7.3568 (5.05); 7.3534 (4.06); 7.3344 (5.27); 7.3291 (3.66); 7.3167 (3.84); 7.3114 (5.88); 7.2994 (1.47); 7.2944 (1.29); 7.1778 (6.49); 7.1668 (3.47); 7.0446 (3.18); 7.0308 (7.36); 6.9071 (7.09); 6.8950 (3.99); 6.4176 (0.41); 6.0072 (0.86); 5.9936 (1.95); 5.9872 (2.75); 5.9807 (2.12); 5.9674 (4.98); 5.9595 (3.43); 5.9541 (1.92); 5.9505 (2.63); 5.9381 (3.78); 5.9244 (2.25); 5.9108 (1.11); 5.7558 (5.44); 5.4556 (1.55); 5.4131 (5.92); 5.3741 (5.41); 5.3316 (1.62); 5.3239 (1.71); 5.3196 (3.63); 5.93151 (4.06); 5.3110 (2.05); 5.2806 (1.17); 52764 (3.01); 5.2719 (3.32); 5.2678 (1.68); 5.1952 (3.19); 5.1907 (3.92); 5.1723 (1.54); 5.1691 (3.07); 5.1645 (3.18); 4.6305 (3.67); 4.6009 (7.35); 4.5488 (7.44); 4.5192 (3.83); 4.3591 (1.58); 4.3260 (1.68); 4.0678 (0.52); 4.0642 (0.44); 4.0580 (0.37); 4.0543 (0.58); 4.0506 (0.50); 4.0386 (2.46); 4.0351 (4.57); 4.0318 (5.15); 4.0284 (5.39); 4.0252 (5.30); 4.0219 (5.45); 4.0183 (5.33); 4.0150 (5.01); 4.0115 (3.20); 3.9955 (1.02); 3.9914 (1.09); 3.9818 (1.86); 3.9450 (1.68); 3.9218 (2.66); 3.8939 (2.88); 3.8785 (3.28); 3.8506 (2.80); 3.4172 (0.51); 3.4080 (1.03); 3.3983 (0.81); 3.3885 (1.91); 3.3793 (2.25); 3.3703 (1.95); 3.9605 (0.89); 3.3500 (1.45); 3.3303 (127.25); 3.3062 (3.48); 3.2866 (3.67); 3.2666 (4.90); 32432 (3.22); 3.2235 (3.24); 3.0376 (0.45); 2.8671 (1.11); 2.8368 (2.01); 2.8100 (1.15); 2.5109 (14.07); 2.5066 (30.04); 2.5021 (41.47); 2.4976 (32.27); 2.4933 (17.59); 2.1298 (1.38); 2.0950 (2.88); 2.0594 (1.70); 1.8440 (0.54); 1.8347 (0.68); 1.8129 (1.29); 1.68051 (1.48); 1.7829 (1.34); 1.7748 (1.28); 1.7534 (0.59); 1.7438 (0.48); 1.6151 (0.49); 1.6043 (0.61); 1.5830 (1.22); 1.5747 (1.38); 1.5531 (1.27); 1.5441 (1.27); 1.5234 (0.56); 1.5143 (0.46); 1.2994 (0.34); 1.2584 (0.47); 1.2341 (0.54); -0.0002 11.62); -0.0083 (0.74

Pr. I-95, Solvent: DMOSO-ab, spectrometer: 399.95 MHz 8.0328 (8.77); 7.4202 (1.31); 7.3995 (2.81); 7.3798 (1.61); 7.1051 (1.81); 7.0888 (4.14); 7.0849 (4.38); 7.0582 (1.65); 7.0528 (1.19); 7.0395 (1.40); 7.0351 (1.35); 7.0306 (1.12); 6.4983 (4.14); 5.7540 (1.13); 5.7333 (1.36); 5.7270 (1.37); 5.7061 (1.19); 5.3499 (0.84); 5.3073 (2.68); 5.2579 (2.58); 5.2154 (0.86); 5.1892 (15.44); 4.3851 (0.68); 4.93523 (0.74); 4.0555 (0.87); 4.0377 (2.66); 4.0199 (2.71); 4.0021 (1.10); 3.9884 (0.69); 3.9542 (0.72); 3.9203 (1.27); 3.8930 (1.45); 3.8773 (1.67); 3.8500 (1.41); 3.4166 (1.70); 3.3958 (1.89); 3.3819 (1.41); 3.3735 (2.22); 3.3530 (3.58); 3.3321 (283.99); 3.3292 (399.61); 3.3252 (431.39); 3.2665 (1.50); 3.2374 (0.90); 2.8663 (0.56); 2.8357 (0.92); 2.8085 (0.54); 2.6795 (0.44); 2.6751 (0.96); 2.6705 (1.37); 2.6660 (1.02); 2.6615 (0.50); 2.5407 (0.64); 2.5239 (2.33); 2.5191 (3.55); 2.5105 (66.94); 2.5060 (142.51); 2.5014 (195.50); 2.4968 (145.36); 2.4923 (79.57); 2.3373 (0.48); 2.3327 (0.98); 2.3282 (1.38); 2.3236 (1.02); 2.3193 (0.54); 2.2069 (16.00); 2.1320 (0.66); 2.0994 (1.37); 2.0735 (1.31); 1.9884 (11.95); 1.8251 (0.62); 1.8149 (0.64); 1.7927 (0.57); 1.7846 (0.54); 1.5834 (0.57); 1.5740 (0.66); 1.5525 (0.59); 1.5433 (0.59); 1.3976 (0.40); 1.2583 (0.33); 1.2358 0.78); 1.1922 (3.28); 1.1745 (6.57); 1.1566 (3.22); -0.0002 (2.54

Pr. I-96, Solvent: DMOSO-ab, spectrometer: 399.95 MHz 8.0364 (7.68); 7.5600 (0.932); 7.5190 (3.72); 7.5145 (1.46); 7.5023 (1.41); 7.4973 (5.27); 7.3952 (0.61); 7.3885 (5.81); 7.3834 (1.83); 7.3718 (1.41); 7.3668 (4.41); 7.3601 (0.61); 6.4989 (4.14); 5.8137 (1.05); 5.7941 (1.25); 5.7866 (1.25); 5.7668 (1.09); 5.3482 (0.84); 5.3057 (2.64); 5.2564 (2.56); 5.2139 (0.84); 4.3856 (0.68); 4.3518 (0.75); 4.0556 (0.65); 4.0378 (2.04); 4.0200 (2.12); 4.0021 (0.89); 3.9858 (0.67); 3.9544 (0.73); 3.9357 (1.26); 3.9082 (1.30); 3.8925 (1.52); 3.8652 (1.26); 3.5129 (1.89); 3.4673 (0.35); 3.4605 (0.39); 3.4490 (0.64); 3.4230 (2.24); 3.4030 (3.01); 3.3841 (27.84); 3.3433 (975.73); 3.2670 (2.02); 3.2369 (1.04); 3.2181 (0.77); 3.2065 (0.58); 3.1885 (0.46); 2.8668 (0.59); 2.8361 (0.95); 2.8089 (0.57); 2.6761 (0.88); 2.6716 (1.21); 2.6671 (0.92); 2.6626 (0.49); 2.5418 (0.70); 2.5249 (2.33); 2.5202 (3.43); 2.5115 (58.98); 2.5070 (125.81); 2.5025 (173.40); 2.4979 (129.49); 2.4934 (65.10); 2.3385 (0.43); 2.3337 (0.86); 2.3292 (1.20); 2.3246 (0.91); 2.2070 (16.00); 2.1320 (0.65); 2.0995 (1.36); 2.0861 (1.11); 2.0730 (1.79); 1.9885 (9.11); 1.8217 (0.57); 1.8134 (0.62); 1.7916 (0.57); 1.7828 (0.54); 1.5829 (0.57); 1.5739 (0.63); 1.5528 (0.58); 1.5432 (0.57); 1.3975 (0.58); 1.2347 (0.76); 1.1924 (2.48); 1.1747 (4.82); 1.1568 (2.40); -0.0002 (10.04); -0.0084 (0.37

Pr. I-97, Solvent: DMOSO-ab, spectrometer: 399.95 MHz 8.0361 (8.30); 7.5327 (0.34); 7.5182 (0.35); 7.5105 (3.77); 7.5060 (1.48); 7.4938 (1.38); 7.4889 (5.22); 7.826 (0.85); 7.3723 (0.58); 7.3655 (5.82); 7.3604 (1.86); 7.3488 (1.44); 7.3437 (4.52); 7.3369 (0.62); 6.4991 (4.18); 5.8104 (1.04); 5.7909 (1.24); 5.7834 (1.23); 5.7636 (1.11); 5.7535 (0.52); 5.3483 (0.85); 5.3060 (2.67); 5.2564 (2.56); 5.2140 (0.85); 4.3859 (0.71); 4.93529 (0.77); 4.0558 (0.62); 4.0380 (1.83); 4.0202 (1.91); 4.0023 (0.84); 3.9876 (0.67); 3.9536 (0.73); 3.9336 (1.22); 3.9062 (1.36); 3.8904 (1.53); 3.8631 (1.25); 3.6756 (0.43); 3.6573 (0.43); 3.5473 (1.78); 3.5289 (5.75); 3.5106 (5.91); 3.4923 (2.01); 3.4182 (2.57); 3, A4101 (1.78); 3.3985 (3.24); 3.3489 (681.51); 3.3454 (828.78); 3.2671 (1.87); 3.2382 (1.00); 3.2200 (0.71); 2.8665 (0.59); 2.8362 (0.97); 2.8095 (0.60); 2.6765 (0.78); 2.6720 (1.08); 2.6674 (0.84); 2.5420 (0.67); 2.5252 (2.06); 2.5205 (3.20); 2.5119 (52.97); 2.5074 (112.35); 2.5028 (153.29); 2, A983 (113.87); 2.4938 (57.02); 2.3341 (0.78); 2.3296 (1.07); 2.3250 (0.81); 2.2075 (16.00); 2.1304 (0.66); 2.1005 (1.36); 2.0730 (2.22); 1.9886 (8.24); 1.8221 (0.59); 1.8137 (0.63); 1.7920 (0.58); 1.7834 (0.54); 1.7603 (0.36); 1.5825 (0.56); 1.5740 (0.63); 1.5519 (0.59); 1.5434 (0.58); 1.4392 (0.44); 1.4210 (0.97); 1.4026 (0.53); 1.3974 (0.38); 1.3890 (5.89); 1.93707 (12.58); 1.3524 (5.72); 1.2349 (0.80); 1.1926 (2.91); 1.1747 (4.59); 1.1570 (2.29); 1.0729 (1.96); 0.9492 (0.52); 0.9337 (0.51); 0.9065 (0.60); -0.0002 (2.74

Pr. I-98, Solvent: DMOSO-ab, spectrometer: 399.95 MHz 8.0379 (8.17); 7.5541 (0.33); 7.5131 (3.66); 7.5086 (1.44); 7.4966 (1.38); 7.4914 (5.35); 7.4000 (0.63); 7.3933 (6.03); 7.3881 (1.88); 7.3767 (1.41); 7.3715 (4.41); 7.3646 (0.61); 6.4989 (4.17); 5.8135 (1.03); 5.7939 (1.24); 5.7865 (1.25); 5.7666 (1.10); 5.7538 (0.54); 5.3488 (0.82); 5.3061 (2.57); 5.2569 (2.50); 5.2140 (0.83); 4.3864 (0.68); 4.3543 (0.74); 4.0558 (0.71); 4.0379 (2.18); 4.0201 (2.25); 4.0022 (0.94); 3.9879 (0.65); 3.9549 (0.73); 3.9380 (1.30); 3.9105 (1.35); 3.8948 (1.53); 3.8675 (1.24); 3.4207 (2.07); 3.4106 (0.98); 3.4009 (2.32); 3.377 (4.37); 3.3489 (308.71); 3.3400 (639.72); 3.2704 (1.74); 3.2379 (1.09); 3.1919 (0.40); 3.1798 (0.36); 3.1600 (0.36); 3.0863 (0.55); 3.0745 (0.98); 3.0664 (1.02); 3.0629 (0.78); 3.0547 (1.89); 3.0467 (0.68); 3.0429 (1.11); 3.0349 (1.06); 3.0231 (0.58); 2.8667 (0.56); 2.8361 (0.94); 2.8091 (0.56); 2.6807 (0.34); 2.6762 (0.70); 2.6716 (1.00); 2.6670 (0.77); 2.6625 (0.39); 2.5417 (0.60); 2.5251 (1.70); 2.5203 (2.53); 2.5116 (47.51); 2.5071 (102.37); 2.5025 (141.26); 2.4979 (105.38); 2.4933 (52.83); 2.3385 (0.38); 2.3339 (0.71); 2.3293 (1.00); 2.3246 (0.76); 2.2072 (16.00); 2.1317 (0.64); 2.1005 (1.34); 2.0862 (0.68); 2.0730 (1.96); 1.9885 (9.99); 1.8224 (0.56); 1.8141 (0.60); 1.7919 (0.56); 1.7832 (0.54); 1.5830 (0.55); 1.5740 (0.62); 1.5532 (0.59); 1.5443 (0.58); 1.3975 (0.89); 1.2529 (0.56); 1.2444 (0.33); 1.2350 (0.89); 1.2019 (0.57); 1.1988 (0.62); 1.1925 (2.94); 1.1879 (2.22); 1.1814 (2.65); 1.1747 (5.90); 1.1679 (2.94); 1.1613 (2.27); 1.1570 (3.28); 1.1510 (0.91); 1.1481 (0.88); 1.0404 (0.62); 1.037 7 (0.90); 1.0267 (2.62); 1.0205 (2.40); 1.0153 (2.34); 1.0090 (2.56); 0.9977 (0.64); 0.9947 (0.49); 0.0080 (0.39); -0.0002 (13.04); -0.0084 (0.52

Pr. I-99, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 9.8999 (0.37); 8.6557 (0.35); 8.0744 (0.36); 8.0441 (8.29); 8.0362 (0.68); 7.5361 (1.95); 7.5164 (3.09); 7.4966 (2.34); 7.4107 (1.94); 7.3911 (1.45); 7.3518 (1.59); 7.3467 (2.55); 7.3425 (1.87); 7.3161 (1.48); 7.3138 (1.59); 7.3101 (1.17); 7.3077 (1.11); 7.2959 (1.17); 7.2935 (1.17); 7.2898 (1.02); 6.4982 (4.53); 5.8266 (1.03); 5.8068 (1.29); 5.7996 (1.20); 5.7794 (1.11); 5.4844 (0.50); 5.3492 (0.91); 5.3069 (2.84); 5.2576 (2.61); 52152 (0.87); 4.3855 (0.75); 4.3528 (0.81); 4.0555 (0.77); 4.0378 (2.25); 4.0200 (2.92); 4.0022 (0.98); 3.9874 (0.73); 3.9509 (1.84); 3.9236 (1.32); 3.9078 (1.52); 3.8804 (1.25); 3.5691 (1.62); 3.5507 (5.46); 3.5324 (5.57); 3.5140 (1.77); 3.4248 (1.56); 3.4049 (1.81); 3.3817 (2.73); 3.3727 (1.27); 3.3619 (2.23); 3.3551 (2.07); 3.3279 (535.35); 3.3262 (587.61); 3.2647 (1.24); 3.2368 (0.70); 3.2288 (0.56); 2.8650 (0.53); 2.8346 (0.89); 2.8078 (0.49); 2.6751 (0.88); 2.6706 (1.26); 2.6661 (0.90); 2.6617 (0.43); 2.5408 (0.64); 2.5240 (2.12); 2.5191 (3.54); 2.5106 (64.31); 2.5060 (138.27); 2.5014 (194.65); 2, A969 (146,41); 2.4924 (71.95); 2.3394 (0.92); 2.3328 (1.01); 2.3283 (1.35); 2.3237 (0.98); 2.3193 (0.50); 2.2068 (16.00); 2.1317 (0.70); 2.0995 (1.39); 2.0736 (1.16); 1.9885 (9.99); 1.8239 (0.60); 1.8157 (0.62); 1.7926 (0.55); 1.7824 (0.53); 1.5824 (0.56); 1.5724 (0.63); 1.5514 (0.60); 1.5435 (0.55); 1.4336 (0.53); 1.4265 (0.43); 1.3916 (5.50); 1.3733 (11.99); 1.3549 (5.58); 1.3369 (0.40); 1.2582 (0.43); 1.2364 (0.83); 1.1923 (2.76); 1.1745 (5.48); 1.1567 (2.67); 0.0080 (1.47); -0.0002 (50.85); - 0.0085 (2.00

Pr. I-100, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0259 (4.56); 7.3756 (0.77); 7.3701 (0.83); 7.3563 (1.17); 7.3369 (0.72); 7.3209 (1.83); 7.3152 (2.15); 7.3082 (2.42); 7.3022 (1.29); 7.2957 (1.88); 7.2903 (1.91); 7.2849 (0.81); 7.2791 (0.77); 7.2739 (0.65); 7.1758 (1.93); 7.1654 (0.95); 7.0426 (0.95); 7.0293 (2.11); 6.9066 (2.08); 6.8935 (1.05); 6.0994 (0.68); 6.0787 (0.99); 6.0719 (0.80); 6.0512 (0.69); 5.4556 (0.47); 5.4128 (1.56); 5.3716 (1.57); 5.3295 (0.51); 4.3657 (0.52); 4.3320 (0.55); 4.0557 (0.66); 4.0379 (1.91); 4.0201 (2.32); 4.0022 (0.80); 3.9891 (1.16); 3.9741 (1.27); 3.9614 (1.29); 3.9464 (1.32); 3.9293 (1.87); 3.8734 (1.83); 3.8410 (0.92); 3.4866 (1.76); 3.4700 (3.97); 3.4536 (2.08); 3.4126 (0.74); 3.3575 (110.14); 3.39531 (132.04); 3.3343 (459.91); 3.3127 (7.55); 3.2915 (2.61); 3.2683 (2.08); 3.2473 (1.69); 3.2387 (4.20); 3, 2330 (16.00); 2.8679 (0.41); 2.8367 (0.73); 2.8057 (0.44); 2.6758 (0.96); 2.6711 (1.25); 2.6666 (1.30); 2.6614 (2.20); 2.6449 (3.682); 2.6284 (1.78); 2.5414 (0.56); 2.5109 (79.34); 2.5068 (120.74); 2.5022 (134.92); 2.4976 (88.43); 2.4931 (37.93); 2.3335 (0.82); 2.3290 (0.94); 2.3243 (0.64); 2.1354 (0.50); 2.1001 (1.03); 2.0732 (1.63); 2.0634 (0.61); 1.9943 (1.90); 1.9886 (8.66); 1.8151 (0.48); 1.7835 (0.45); 1.5820 (0.46); 1.5733 (0.44); 1.5513 (0.48); 1.3976 (0.55); 1.2411 (0.46); 1.1924 (2.37); 1.1803 (1.00); 1.1746 (4.70); 1.1568 2.26); 0.0055 (0.75); -0.0002 (3.72

Pr. I-101, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0443 (8.70); 8.0363 (0.59); 7.5371 (1.30); 7.5173 (3.20); 7.4975 (2.33); 7.4184 (2.00); 7.3990 (1.51); 7.3854 (1.82); 7.3799 (2.71); 7.3405 (1.47); 7.3383 (1.60); 7.3346 (1.35); 7.3324 (1.24); 7.3204 (1.26); 7.3181 (1.24); 7.3144 (1.14); 7.3121 (1.01); 6.4982 (4.47); 5.8323 (1.05); 5.8126 (1.27); 5.8052 (1.29); 5.7855 (1.17); 5.4847 (0.39); 5.3492 (0.91); 5.3067 (2.80); 52577 (2.67); 5.2153 (0.87); 4.3834 (0.74); 4.3508 (0.78); 4.0557 (0.85); 4.0378 (2.48); 4.0200 (2.53); 4.0022 (1.01); 3.9870 (0.71); 3.9541 (1.86); 3.9266 (1.42); 3.9109 (1.60); 3.8837 (1.29); 3.4171 (1.79); 3.4092 (0.78); 3.3976 (1.77); 3.3902 (0.78); 3.3806 (1.35); 3.3736 (2.03); 3.3541 (2.68); 3.3254 (486.84); 3.2654 (1.36); 3.2371 (0.60); 3.1128 (0.43); 3.1010 (0.93); 3.0929 (0.97); 3.0894 (0.68); 3.0812 (1.83); 3.0732 (0.60); 3.0695 (1.01); 3.0613 (0.98); 3.0496 (0.50); 2.8648 (0.53); 2.8348 (0.92); 2.8076 (0.50); 2.6794 (0.38); 2.6750 (0.79); 2.6705 (1.09); 2.6660 (0.79); 2.5407 (0.60); 2.5239 (1.98); 2.5191 (3.23); 2.5105 (55.78); 2.5060 (119.13); 2.5013 (167.08); 2.4968 (125.22); 2.4923 (61.24); 2.3400 (0.75); 2.3327 (0.84); 2.3283 (1.11); 2.3237 (0.84); 2.3192 (0.42); 22069 (16.00); 2.1310 (0.67); 2.1003 (1.35); 2.0736 (0.91); 1.9885 (11.11); 1.8215 (0.58); 1.8119 (0.61); 1.7903 (0.58); 1.7822 (0.53); 1.5812 (0.55); 1.5717 (0.66); 1.5515 (0.57); 1.5420 (0.57); 1.2360 (0.56); 1.1923 (3.12); 1.1852 (0.52); 1.1745 (6.55); 1.1688 (1.87); 1.1628 (2.62); 1.1567 (3.47); 1.1478 (2.16); 1.1430 (2.65); 1.1278 (0.69); 1.0192 (0.79); 1.0164 (0.74); 1.0068 (2.25); 0.9995 (2.43); 0.9943 (1.98); 0.9897 (1.65); 0.9787 (0.60); 0.0081 (0.82); -0.0002 (28.08); -0.0084 1.03

Pr. I-102, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0559 (5.76); 7.5877 (0.59); 7.5833 (0.84); 7.5678 (2.32); 7.5632 (2.37); 7.5584 (2.09); 7.5388 (2.80); 7.5189 (1.35); 7.4908 (2.14); 7.4863 (2.01); 7.4714 (1.19); 7.4668 (1.04); 7.3139 (1.01); 7.1807 (2.33); 7.1678 (1.10); 7.0475 (1.13); 7.0317 (2.54); 6.9072 (2.33); 6.8959 (1.25); 6.1931 (0.99); 6.1656 (1.49); 6.1629 (1.38); 6.1352 (1.02); 5.7569 (2.74); 5.4626 (0.54); 5.4200 (1.83); 5.3783 (1.83); 5.3358 (0.53); 4.3707 (0.54); 4.3370 (0.56); 4.0378 (0.46); 4.0200 (0.46); 3.9882 (0.50); 3.9545 (0.55); 3.8641 (0.79); 3.332 (0.94); 3.8208 (1.20); 3.7901 (0.993; 3.5931 (1.15); 3.5660 (1.17); 3.5499 (0.98); 3.5323 (16.00); 3.5230 (1.19) ; 3.4284 (0.38); 3.4084 (0.45); 3.3994 (0.80); 3.3903 (0.46); 3.3709 (0.42); 3.3198 ( 18.47); 3.2968 (0.73); 3.2694 (0.71); 3.2409 (0.40); 2.8699 (0.38); 2.8395 (0.68); 2.8125 (0.39); 2.5235 (0.59); 2.5101 (14.00); 2.5057 (28.45); 2.5013 (37.56); 2.4968 (26 .82); 2.4924 (12.77); 2.1496 (0.48); 2.1159 (0.99); 2.0819 (0.55); 1.9887 (1.88); 1 .8256 (0.44); 1.7997 (0.40); 1.5836 (0.43); 1.5610 (0.40); 1.5529 (0.39); 1.1921 (0, 53); 1.1743 (1.04); 1.1566 (0.51); -0.0002 (1.21

Pr. I-103, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0529 (5.93); 7.5869 (0.53); 7.5824 (0.77); 7.5670 (2.15); 7.5623 (2.27); 7.5579 (2.11); 7.5384 (2.68); 7.5184 (1.32); 7.4901 (2.00); 7.4856 (1.97); 7.4707 (1.17); 7.4661 (1.04); 6.4981 (2.78); 6.1919 (0.90); 6.1646 (1.31); 6.1616 (1.27); 6.1341 (0.94); 5.7542 (3.07); 5.3528 (0.57); 5.9102 (1.76); 5.2596 (1.69); 52171 (0.57); 5.1958 (0.42); 4.3913 (0.48); 4.3584 (0.52); 4.0558 (0.75); 4.0380 (2.27); 4.0202 (2.92); 4.0024 (1.02); 3.9929 (0.48); 3.9582 (0.51); 3.8638 (0.70); 3.8330 (0.86); 3.8205 (1.09); 3.7898 (0.90); 3.5921 (1.05); 3.5650 (1.03); 3.5489 (0.89); 3.5295 (16.00); 3.5221 (1.50); 3.4228 (0.45); 3.4138 (0.39); 3.4034 (0.59); 3.3938 (1.04); 3.3843 (0.87); 3.3446 (97.60); 3.3412 (154.65); 3.3356 (273.64); 3.2710 (1.04); 3.2424 (0.58); 3.2362 (0.49); 3.0430 (0.94); 2.8716 (0.36); 2.8548 (0.88); 2.8436 (0.64); 2.8132 (0.36); 2.6713 (0.44); 2.6668 (0.34); 2.5246 (0.88); 2.5112 (22.73); 2.5068 (46.88); 2.5022 (63.49); 2.4976 (47.55); 2.4932 (24.33); 2.3336 (0.33); 2.3289 (0.44); 2.3242 (0.33); 2.2087 (10.45); 2.1928 (1.05); 2.1485 (0.49); 2.1167 (0.95); 2.0998 (0.43); 2.0865 (0.55); 2.0732 (0.70); 1.9886 (10.04); 1.8256 (0.43); 1.8013 (0.37); 1.5901 (0.937); 1.5813 (0.39); 1.5604 (0.36); 1.5512 (0.36); 1.1924 (2.79); 1.1747 (5.53); 1.1569 (2.75); -0.0002 (6.38

Pr. I-104, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0255 (7.87); 7.4733 (1.41); 7.4692 (1.69); 7.4543 (1.81); 7.4498 (2.49); 74441 (0.93); 7.4290 (2.04); 7.4250 (1.64); 7.4097 (1.62); 7.4055 (1.27); 7.3424 (1.38); 7.3396 (1.55); 7.3236 (2.04); 7.3207 (2.14); 7.3050 (0.85); 7.3021 (0.81); 7.2488 (2.50); 7.2464 (2.35); 7.2288 (2.00); 7.2266 (1.78); 6.5392 (1.62); 6.5363 (1.71); 6.5047 (4.46); 6.4961 (2.94); 6.4931 (2.81); 6.3744 (2.04); 6.3485 (2.67); 6.3313 (1.28); 6.3052 (1.57); 6.1209 (2.31); 6.1183 (2.27); 6.0952 (1.80); 6.0923 (1.92); 5.7899 (1.18); 5.7 707 (1.43); 5.7615 (1.43); 5.7419 (1.26); 5.3598 (0.96); 5.3169 (2.54); 5.2630 (2.54); 5.2205 (0.95); 4.3861 (0.77); 4.3535 (0.81); 3.9855 (0.78); 3.9499 (0.84); 3.8801 (1.24); 3.8515 (1.50); 3.8370 (1.69); 3.8086 (1.39); 3.5802 (0.38); 3.57 71 (0.47); 3.5680 (0.38); 3.5593 (0.39); 3.5504 (0.35); 3.5199 (0.45); 3.5067 (0.53); 3.4924 (0.50); 3.4804 (0.63); 3.4599 (0.60); 3.3662 (371.90); 3.3627 (408.35); 3.93576 (412.22); 3.3535 (509.10); 3.3089 (2.27); 3.2895 (2.38); 3.2655 (2.23); 3.2464 (1.60); 3.2310 (0.58); 3.2250 (0.45); 2.8641 (0.46); 2.8591 (0.52); 2.8277 (0.96); 2.8014 (0.57); 2.6770 (1.44); 2.6725 (2.02); 2.6681 (1.50); 2.5429 (1.17); 2.5260 (3.37); 2.5213 (5.36); 2.5125 (106.97); 2.5081 (231.40); 2.5035 (311.24); 2, A990 (221.48); 2.4944 (104.20); 2.4521 (0.33); 2.3393 (0.67); 2.3348 (1.45); 2.3302 (2.00); 2.3256 (1.49); 2.2050 (16.00); 2.1263 (0.68); 2.0933 (1.41); 2.0774 (9.07); 2.0649 (0.87); 1.8119 (0.57); 1.8064 (0.64); 1.7812 (0.56); 1.5710 (0.59); 1.5602 (0.60); 1.5394 (0.64); 1.5304 (0.60); 1.2346 (1.09); 0.0080 (1.37); -0.0002 (53.87); -0.0085 (2.06

Pr. I-105, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 9.8988 (0.38); 8.6666 (0.38); 8.0444 (10.51); 7.6665 (0.35); 7.6615 (0.37); 7.5583 (0.35); 7.5373 (0.58); 7.5120 (4.58); 7.5075 (1.83); 7.4952 (2.04); 7.4904 (6.14); 7.4840 (1.04); 7.4742 (0.40); 7.4686 (0.92); 7.3759 (0.95); 7.3692 (7.09); 7.3640 (2.32); 7.3525 (1.98); 7.3474 (5.54); 7.3405 (0.79); 7.3157 (1.73); 7.1824 (4.04); 7.1743 (2.23); 7.0494 (2.00); 7.0383 (4.86); 6.9151 (4.23); 6.9025 (2.45); 5.8134 (1.24); 5.7938 (1.53); 5.7862 (1.49); 5.7664 (1.931); 5.4645 (1.01); 5.4218 (3.16); 5.3795 (3.09); 5.3368 (1.04); 4.3650 (0.98); 4.3334 (1.01); 4.0546 (0.73); 4.0368 (2.27); 4.0190 (2.31); 4.0011 (0.94); 3.9831 (0.90); 3.9480 (1.05); 3.9348 (1.65); 3.9073 (1.65); 3.8916 (1.84); 3.8643 (1.44); 3.6822 (0.62); 3.6638 (0.64); 3.5520 (1.95); 3.5337 (6.61); 3.5153 (6.80); 3.4971 (2.26); 3.4687 (0.33); 3.4493 (0.56); 3.4204 (3.01); 3.3742 (362.17); 3.3650 (293.54); 3.3614 (310.52); 3.2995 (1.55); 3.2936 (1.57); 3.2630 (1.83); 3.2345 (1.12); 2.8623 (0.77); 2.8321 (1.30); 2.8055 (0.76); 2.6778 (0.83); 2.6732 (1.13); 2.6686 (0.84); 2.65642 (0.44); 2.5435 (0.58); 2.5263 (2.90); 2.5191 (62.32); 2.5086 (126.10); 2.5041 (165.60); 2.4995 (120.37); 2.4951 (59.88); 2.3353 (0.87); 2.3308 (1.16); 2.3262 (0.88); 2.1298 (0.93); 2.0972 (1.84); 2.0773 (1.99); 2.0646 (1.07); 1.9904 (10.53); 1.9626 (0.64); 1.8389 (0.46); 1.8175 (0.82); 1.8092 (0.89); 1.7870 (0.81); 1.7789 (0.77); 1.7567 (0.38); 1.6110 (0.38); 1.6013 (0.46); 1.5803 (0.82); 1.5711 (0.90); 1.5497 (0.89); 1.5410 (0.80); 1.5198 (0.39); 1.5107 (0.33); 1.4383 (0.77); 1.4200 (1.59); 1.4017 (0.91); 1.3967 (0.71); 1.3883 (7.30); 1.53700 (16.00); 1.3516 (7.20); 1.2580 (0.34); 1.2350 (0.58); 1.1921 (3.01); 1.1743 (5.94); 1.1565 (2.93); 0.0080 (0.56); -0.0002 (14.07); -0.0085 (0.61

Pr. I-106, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 9.8988 (0.42); 8.6666 (0.40); 8.0461 (11.60); 7.6713 (0.43); 7.6663 (0.43); 7.5798 (0.45); 7.5588 (0.64); 7.5149 (5.00); 7.5104 (2.01); 7.4982 (2.31); 7.4934 (7.22); 7.4869 (1.27); 7.4796 (0.58); 7.4743 (0.41); 7.4040 (1.20); 7.3973 (8.41); 7.3921 (2.66); 7.3806 (2.22); 7.3755 (6.10); 7.3688 (0.92); 7.3157 (1.99); 7.1825 (4.64); 7.1742 (2.56); 7.0494 (2.26); 7.0382 (5.57); 6.9153 (4.88); 6.9025 (2.82); 5.8166 (1.41); 5.7970 (1.73); 5.7896 (1.71); 5.7697 (1.48); 5.4647 (1.15); 5.4221 (3.55); 5.3797 (3.52); 5.3369 (1.21); 4.3664 (1.09); 4.3345 (1.16); 4.0546 (1.12); 4.0368 (3.43); 4.0190 (3.51); 4.0012 (1.37); 3.9843 (1.02); 3.9394 (2.10); 3.9119 (1.91); 3.8962 (2.10); 3.8688 (1.67); 3.4719 (0.37); 3.4530 (0.54); 3.4232 (3.91); 3.3757 (421.85); 3.3733 (400.20); 3.3655 (363.95); 3.3612 (465.90); 3.2948 (1.93); 3.2634 (2.13); 3.2352 (1.26); 3.1890 (0.48); 3.1808 (0.47); 3.1691 (0.55); 3.1573 (0.45); 3.1493 (0.43); 3.0951 (0.73); 3.0834 (1.38); 3.0753 (1.46); 3.0718 (1.12); 3.0636 (2.60); 3.0555 (1.07); 3.0518 (1.58); 3.0438 (1.48); 3.0321 (0.83); 2.8627 (0.88); 2.8349 (1.51); 2.8056 (0.90); 2.6778 (1.09); 2.6733 (1.49); 2.6687 (1.14); 2.6642 (0.60); 2.5436 (0.83); 2.5266 (3.48); 2.5132 (80.40); 2.5088 (164.89); 2.5042 (217.64); 2, A996 (158,20); 2.4952 (78.41); 2.3399 (0.58); 2.3355 (1.13); 2.3309 (1.52); 2.3263 (1.14); 2.1306 (1.08); 2.0981 (2.11); 2.0773 (2.50); 2.0652 (1.23); 1.9904 (16.00); 1.8386 (0.51); 1.8175 (0.93); 1.8096 (0.99); 1.7870 (0.93); 1.7790 (0.86); 1.7581 (0.43); 1.6115 (0.41); 1.6019 (0.51); 1.5810 (0.93); 1.5717 (1.04); 1.5503 (0.97); 1.5414 (0.96); 1.5200 (0.45); 1.5104 (0.42); 1.2814 (0.33); 1.2650 (0.42); 1.2577 (0.47); 1.2533 (0.63); 1.2446 (0.78); 1.2338 (1.24); 1.2182 (0.46); 1.2022 (0.93); 1.1991 (1.04); 1.1921 (5.22); 1.1882 (3.46); 1.1817 (3.99); 1.1794 (3.55); 1.1743 (10.13); 1.1682 (4.49); 1.1615 (3.44); 1.1565 (5.32); 1.1514 (1.46); 1.1483 (1.40); 1.1313 (0.41); 1.1162 (0.39); 1.1057 (0.50); 1.0988 (0.48); 1.0879 (0.46); 1.0744 (0.34); 1.0374 (1.06); 1.0346 (1.47); 1.0237 (3.87); 1.0174 (3.70); 1.0146 (3.22); 1.0123 (3.51); 1.0060 (3.74); 0.9948 (1.14); 0.9917 (0.80); 0.0080 (0.89); -0.0002 (22.71); - 0.0085 (0.98

Pr. I-107, Solvent: dmeoo-avb, spectrometer: 601.6 MHz 8.0699 (1.56); 8.0655 (0.77); 8.0584 (7.96); 7.5193 (0.34); 7.5151 (0.40); 7.5050 (0.39); 7.5006 (0.49); 7.4713 (0.86); 7.4636 (1.87); 7.4614 (2.09); 7.4508 (2.21); 7.4486 (2.53); 7.4430 (1.33); 7.4403 (1.19); 7.4300 (2.12); 7.4276 (1.94); 74171 (1.54); 7.4145 (1.35); 7.3742 (0.83); 7.3598 (0.68); 7.3442 (1.62); 7.3329 (2.38); 7.3316 (2.45); 7.3207 (1.06); 7.3191 (1.05); 7.2725 (3.57); 7.2608 (2.40); 7.1823 (3.64); 7.1295 (1.72); 7.0938 (1.77); 7.0391 (4.06); 6.9488 (1.91); 6.9148 (4.68); 5.7868 (0.36); 5.7 769 (1.49); 5.7638 (1.66); 5.7583 (1.65); 5.7450 (1.39); 5.4582 (1.61); 5.4298 (3.23); 5.3738 (3.32); 5.3454 (1.65); 4.3587 (1.17); 4.3369 (1.21); 4.0452 (1.26); 4.0334 (3.79); 4.0215 (3.80); 4.0097 (1.29); 3.9748 (1.11); 3.9526 (1.18); 3.8896 (1.39); 3.8760 (0.49); 3.8707 (1.59); 3.8610 (1.74); 3.8422 (1.39); 3.4149 (0.73); 3.4087 (1.16); 3.4032 (1.01); 3.3962 (1.84); 3.3897 (2.67); 3.3831 (2.87); 3.3565 (1558.53); 3.3329 (19.82); 3.3228 (3.19); 3.3095 (2.26); 3.2941 (1.84); 3.2810 (2.38); 3.2617 (1.60); 3.2425 (0.89); 2.8509 (0.80); 2.8307 (1.47); 2.8120 (0.79); 2.6182 (2.02); 2.6153 (2.72); 2.6125 (2.09); 2.5430 (1.16); 2.5242 (5.92); 2.5213 (8.67); 2.5064 (320.67); 2.5036 (426.88); 2.5008 (331.00); 2.3906 (2.11); 2.3877 (2.79); 2.3849 (2.16); 21233 (1.07); 2.0969 (1.31); 2.0870 (1.24); 2.0786 (4.62); 2.0647 (1.16); 1.9907 (16.00); 1.9057 (0.64); 1.8946 (1.70); 1.8824 (4.85); 1.8782 (5.67); 1.8666 (1.06); 1.8551 (0.51); 1.8286 (0.45); 1.8218 (0.48); 1.8074 (0.95); 1.8021 (1.04); 1.7873 (0.98); 1.7816 (0.93); 1.7674 (0.44); 1.7608 (0.36); 1.5976 (0.58); 1.5935 (0.66); 1.5883 (1.18); 1.5814 (1.86); 1.5756 (3.26); 1.5714 (3.24); 1.5694 (3.15); 1.5649 (3.69); 1.5464 (1.43); 1.5416 (1.24); 1.5260 (0.46); 1.5203 (0.38); 1.4070 (0.47); 1.3970 (0.80); 1.2575 (0.42); 1.2343 (1.09); 1.1859 (4.28); 1.1741 (8.54); 1.1622 (4.23); 0.8535 0.40); 0.0965 (0.42); 0.0050 (4.85); -0.0002 (93.16); -0.1001 (0.44

Pr. I-108, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 9.9110 (0.70); 9.8838 (0.77); 9.7909 (2.81); 8.4610 (1.53); 8.4349 (1.62); 8.3176 (5.06); 8.3133 (5.05); 8.0366 (10.84); 8.0276 (3.57); 7.9519 (0.80); 7.5932 (2.45); 7.5736 (2.93); 7.4029 (3.08); 7.3857 (3.78); 7.3669 (0.48); 7.3489 (1.89); 7.3338 (3.25); 7.3151 (2.91); 7.3093 (3.77); 7.2821 (0.84); 7.2580 (2.32); 7.2391 (2.74); 7.2208 (1.15); 7.1756 (6.61); 7.1651 (3.21); 7.0427 (3.18); 7.0291 (7.47); 6.9065 (6.42); 6.8931 (3.59); 6.0352 (0.48); 6.0169 (0.61); 6.0068 (0.59); 5.9895 (0.56); 5.9082 (1.55); 5.8893 (1.80); 5.8811 (1.74); 5.8617 (1.52); 5.7532 (9.02); 5.4545 (1.40); 5.4401 (0.34); 5.4126 (4.85); 5.3848 (0.49); 5.3696 (4.87); 5.3265 (1.59); 5.3142 (0.95); 4.3603 (1.43); 4.3300 (1.48); 4.0560 (1.24); 4.0381 (3.65); 4.0202 (3.67); 4.0025 (1.29); 3.9781 (1.40); 3.9442 (3.12); 3.9171 (2.12); 3.9082 (1.09); 3.9006 (2.14); 3.8733 (1.75); 3.4700 (0.37); 3.4589 (0.935); 3.4388 (0.47); 3.4080 (1.48); 3.3793 (3.98); 3.3488 (505.10); 3.3438 (1135.71); 3.3206 (18.94); 3.2516 (3.82); 3.2314 (3.41); 3.2073 (2.42); 3.1878 (1.94); 3.1596 (0.35); 2.8907 (5.76); 2.8588 (1.12); 2.8295 (1.87); 2.8008 (1.09); 2.7310 (4.97); 2.6765 (0.92); 2.68716 (1.26); 2.6667 (0.98); 2.5418 (0.85); 2.5070 (149.08); 2.5027 (203.49); 2.4986 (145.34); 2.4073 (0.40); 2.3293 (1.37); 2.3246 (1.04); 2.3206 (0.62); 21251 (1.28); 2.0909 (2.57); 2.0729 (2.09); 2.0583 (1.47); 1.9885 (16.00); 1.8444 (0.50); 1.8025 (1.18); 1.7801 (1.20); 1.7735 (1.11); 1.7433 (0.49); 1.5973 (0.61); 1.5776 (1.15); 1.5682 (1.24); 1.5471 (1.13); 1.5381 (1.10); 1.5161 (0.55); 1.5051 0.41); 1.2369 (0.79); 1.1925 (4.25); 1.1747 (8.36); 1.1569 (4.06); -0.0002 (2.40

Pr. I-109, Solvent: dmeoo-avb, spectrometer: 601.6 MHz 9.9404 (0.32); 9.9227 (0.35); 9.8187 (1.48); 8.7946 (0.39); 8.4595 (0.71); 8.4523 (0.45); 8.4419 (0.70); 8.3171 (2.61); 8.3145 (2.69); 8.0453 (5.68); 8.0353 (1.96); 7.5919 (1.33); 7.5786 (1.48); 7.3988 (1.57); 7.3966 (1.71); 7.3858 (1.97); 7.3837 (2.05); 7.3464 (1.05); 7.3440 (0.78); 7.3339 (1.61); 7.3208 (1.47); 7.3185 (1.47); 7.3076 (0.36); 7.2745 (0.33); 7.2620 (0.50); 7.2502 (1.14); 7.2378 (1.42); 7.2251 (0.65); 6.5051 (4.25); 6.0185 (0.34); 6.0126 (0.34); 5.9006 (0.80); 5.8879 (0.91); 5.8825 (0.90); 5.8697 (0.81); 5.7632 (0.65); 5.3469 (1.29); 5.3185 (2.60); 5.2590 (2.50); 5.2307 (1.27); 4.3804 (0.74); 4.3587 (0.77); 4.0455 (0.49); 4.0336 (1.34); 4.0218 (1.33); 4.0099 (0.45); 3.9766 (0.70); 3.9534 (0.76); 3.9399 (0.44); 3.9338 (0.93); 3.9214 (0.43); 3.9155 (1.10); 3.9113 (0.52); 3.9050 (1.13); 3.8929 (0.40); 3.8867 (0.96); 3.5679 (0.40); 3.4111 (0.56); 3.3999 (1.06); 3.3941 (2.07); 3.3897 (2.08); 3.3666 (1439.30); 3.3432 (6.28); 3.3350 (1.30); 3.3126 (0.36); 3.2758 (0.68); 3.2585 (1.22); 3.2467 (0.64); 3.2382 (1.47); 3.2310 (0.80); 3.2258 (1.10); 3.2182 (0.49); 3.2097 (0.96); 3.1970 (0.94); 2.8909 (2.42); 2.8430 (0.55); 2.8243 (0.96); 2.8048 (0.55); 2.7307 (1.86); 2.6189 (0.85); 2.6159 (1.17); 2.6129 (0.86); 2.5436 (0.61); 2.5251 (2.10); 2.5221 (2.75); 2.5190 (3.14); 2.5101 (61.66); 2.5072 (130.20); 2.5042 (175.90); 2.5012 (125.77); 2.4982 (56.95); 2.3913 (0.79); 2.3883 (1.09); 2.3853 (0.78); 2.2039 (16.00); 2.1935 (0.80); 2.1189 (0.68); 2.0941 (1.20); 2.0777 (1.69); 2.0669 (0.72); 1.9905 (5.83); 1.8101 (0.59); 1.8042 (0.63); 1.7896 (0.60); 1.7838 (0.57); 1.5635 (0.58); 1.5573 (0.63); 1.5429 (0.60); 1.5369 (0.58); 1.4188 (5.51); 1.2347 (0.53); 1.1861 (1.52); 1.1742 (3.03); 1.1624 (1.49); -0.0002 (6.39

Pr. I-110, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0321 (9.05); 7.4217 (1.23); 7.4009 (2.81); 7.3815 (1.77); 7.3103 (1.48); 7.1770 (3.42); 7.1656 (1.70); 7.1062 (1.90); 7.0892 (4.37); 7.0853 (4.23); 7.0592 (1.77); 7.0526 (1.29); 7.0437 (1.85); 7.0406 (1.81); 7.0352 (1.45); 7.0297 (4.45); 6.9069 (3.17); 6.8938 (1.98); 5.7535 (1.91); 5.7348 (1.39); 5.7283 (1.40); 5.7076 (1.26); 5.4566 (0.76); 5.4139 (2.56); 5.3719 (2.55); 5.3294 (0.78); 5.1880 (16.00); 4.3624 (0.75); 4.3296 (0.77); 4.0378 (0.50); 4.0201 (0.49); 3.9821 (0.74); 3.9492 (0.78); 3.9209 (1.36); 3.8936 (1.55); 3.8779 (1.77); 3.8506 (1.51); 3.7054 (0.47); 3.6841 (0.34); 3.4806 (0.75); 3.4160 (4.44); 3.3952 (6.81); 3.3494 (1409.91); 3.3462 (1693.59); 3.2380 (1.77); 2.8669 (0.67); 2.8365 (1.07); 2.8092 (0.66); 2.6764 (1.60); 2.6718 (2.26); 2.6673 (1.71); 2.6628 (0.91); 2.5420 (1.49); 2.5252 (4.18); 2.5204 (6.24); 2.5118 (103.86); 2.5073 (221.88); 2.5027 (305.28); 2.4982 (226.97); 2.4937 (113.55); 2.3341 (1.46); 2.3295 (2.07); 2.3249 (1.58); 2.3204 (0.78); 2.1356 (0.66); 2.0989 (1.35); 2.0728 (7.95); 1.9885 (1.96); 1.8097 (0.64); 1.7875 (0.57); 1.7600 (0.40); 1.5843 (0.59); 1.5764 (0.64); 1.5543 (0.61); 1.5451 (0.58); 1.3976 (0.937); 1.2348 (1.62); 1.1925 (0.59); 1.1747 (1.20); 1.1596 (2.00); 1.1030 (3.08); 0.9581 (0.79); 0.9426 (0.82); 0.9065 (1.80); 0.8896 (0.33); -0.0002 (7.71

Pr. I-111, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0375 (9.29); 7.3766 (0.71); 7.3718 (0.83); 7.3567 (1.06); 7.3519 (1.19); 7.3482 (0.87); 7.3420 (0.87); 7.3294 (0.96); 7.3234 (1.19); 7.2746 (0.69); 7.2625 (0.60); 7.2550 (1.72); 7.2430 (1.77); 7.2352 (1.29); 7.2250 (3.12); 7.2211 (3.32); 7.2066 (0.85); 7.2013 (0.70); 6.4977 (4.08); 5.9676 (1.26); 5.9489 (1.47); 5.9396 (1.48); 5.9208 (1.92); 5.7542 (0.47); 5.3474 (0.83); 5.3048 (2.63); 5.2556 (2.56); 5.2129 (0.85); 5.1403 (13.00); 4.3826 (0.70); 4.3495 (0.72); 4.0378 (0.76); 4.0200 (0.81); 4.0022 (0.38); 3.9839 (0.67); 3.9732 (1.57); 3.9450 (1.98); 3.9298 (1.73); 3.9017 (1.41); 3.6012 (0.38); 3.4507 (0.56); 3.4086 (1.56); 3.3862 (4.60); 3.3672 (9.36); 3.3383 (224446); 3.2362 (1.38); 3.2062 (0.77); 2.8651 (0.63); 2.8348 (0.97); 2.8078 (0.58); 2.6802 (0.82); 2.6758 (1.76); 2.6712 (2.51); 2.6666 (1.86); 2.6620 (0.93); 2.5414 (1.58); 2.5246 (4.44); 2.5199 (6.56); 2.5112 (119.04); 2.5067 (255.24); 2.5021 (351.18); 2, A975 (259.86); 2.4930 (128.63); 2.3381 (0.79); 2.3334 (1.74); 2.3289 (2.42); 2.3243 (1.81); 2.3198 (0.92); 2.2059 (16.00); 2.1313 (0.64); 2.1026 (1.33); 2.0859 (0.95); 2.0731 (7.19); 1.9885 (3.47); 1.8203 (0.56); 1.8115 (0.62); 1.7904 (0.56); 1.7813 (0.54); 1.7600 (0.63); 1.7512 (0.33); 1.5808 (0.57); 1.5721 (0.64); 1.5500 (0.60); 1.5408 (0.58); 1.4042 (0.66); 1.3976 (4.45); 1.2347 (1.74); 1.1924 (0.96); 1.1746 (1.94); 1.1568 (0.93); 1.0122 (0.39); 0.8896 (0.57); 0.0080 (0.54); -0.0002 (19.05); -0.0085 0.69

Pr. I-112, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0116 (5.21); 7.3254 (1.71); 7.3207 (0.98); 7.3083 (2.59); 7.2903 (0.96); 7.2859 (0.55); 7.1753 (1.95); 7.1649 (0.94); 7.1397 (1.46); 7.1198 (1.07); 7.1174 (1.04); 7.0422 (0.92); 7.0289 (2.18); 7.0154 (0.81); 6.9950 (1.39); 6.9782 (0.67); 6.9054 (1.91); 6.8931 (1.08); 5.8995 (0.70); 5.8815 (0.81); 5.8719 (0.81); 5.8536 (0.73); 5.7547 (4.42); 5.4534 (0.42); 5.4109 (1.44); 5.3696 (1.41); 5.3307 (6.82); 4.3558 (0.41); 4.3220 (0.43); 4.0380 (0.67); 4.0202 (0.68); 3.9737 (0.43); 3.9428 (0.42); 3.9014 (0.74); 3.8734 (0.87); 3.8586 (0.99); 3.8307 (0.82); 3.4042 (0.39); 3.3943 (0.36); 3.3829 (0.62); 3.3747 (1.19); 3.3509 (50.54); 3.3451 (48.30); 3.3371 (49.80); 3.3334 (57.03); 3.3283 (74.39); 3.3165 (1.92); 3.3050 (0.89); 3.2981 (1.33); 3.2733 (1.01); 5.2553 (1.18); 2.8377 (0.51); 2.8353 (0.51); 2.5243 (0.60); 2.5103 (18.88); 2.5062 (35.71); 2.5020 (48.65); 2.4978 (33.62); 2.4936 (16.51); 2.1972 (16.00); 2.1235 (0.36); 2.0919 (0.73); 2.0733 (1.72); 2.0552 (0.40); 1.9885 (3.02); 1.8013 (0.34); 1.5759 (0.92); 1.5675 (0.35); 1.5449 (0.33); 1.5354 (0.33); 1.3512 (0.99); 1.2493 (0.37); 1.2291 (0.97); 1.1924 (0.84); 1.1746 (1.66); 1.1568 (0.81); 0.0080 (0.49); -0.0002 (17.08); -0.0085 (0.51

Pr. I-113, Solvent: dmeoo-avb, spectrometer: 601.6 MHz 8.0036 (9.73); 7.5028 (0.98); 7.4888 (2.15); 7.4777 (2.15); 7.4638 (1.04); 7.2747 (1.68); 7.1861 (3.81); 7.1311 (1.80); 7.0977 (1.90); 7.0795 (3.62); 7.0654 (3.39); 7.0406 (4.19); 7.0143 (1.75); 6.9982 (2.40); 6.9833 (1.64); 6.9503 (1.99); 6.9162 (5.07); 6.0635 (1.69); 6.0487 (1.96); 6.0434 (1.91); 6.0284 (1.71); 5.7652 (16.00); 5.4601 (1.77); 5.4317 (3.74); 5.3802 (3.70); 5.3518 (1.80); 5.2493 (0.33); 5.2215 (12.81); 4.3628 (1.28); 4.3410 (1.31); 4.0335 (0.90); 4.0216 (0.91); 4.0098 (0.33); 3.9838 (1.20); 3.9606 (1.28); 3.8302 (1.27); 3.8098 (1.49); 3.8020 (1.65); 3.7816 (1.46); 3.6289 (0.44); 3.5185 (1.82); 3.5036 (1.88); 3.4901 (1.58); 3.4753 (1.56); 3.4223 (0.55); 3.4161 (0.96); 3.4095 (0.75); 3.4032 (1.15); 3.3969 (2.10); 3.3906 (1.60); 3.3837 (1.67); 3.3576 (441.62); 3.3343 (2.59); 3.2916 (0.92); 3.2719 (1.68); 3.2526 (0.88); 2.8626 (0.87); 2.8423 (1.61); 2.8243 (0.89); 2.6155 (0.86); 2.5430 (0.42); 2.5037 (131.96); 2.3879 (0.81); 2.1420 (1.10); 21213 (1.931); 2.1021 (1.19); 2.0787 (1.41); 1.9907 (3.70); 1.8439 (0.37); 1.8385 (0.44); 1.8238 (0.97); 1.8184 (1.04); 1.8034 (0.97); 1.7982 (0.92); 1.7836 (0.37); 1.6075 (0.38); 1.6008 (0.46); 1.5868 (0.99); 1.5806 (1.07); 1.5665 (1.02); 1.5604 (0.97); 1.5467 (0.39); 1.5398 (0.32); 1.2336 (0.52); 1.1859 (1.01); 1.1741 (1.98); 1.1623 (0.99); -0.0002 (5.55

Pr. I-114, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.7867 (0.91); 8.0701 (8.24); 7.4590 (2.45); 7.4528 (1.51); 7.4401 (3.25); 7.4293 (1.92); 74267 (1.99); 7.3287 (1.20); 7.3186 (1.56); 7.3099 (0.82); 7.3046 (0.91); 6.4974 (4.70); 6.0358 (1.09); 6.0170 (1.23); 6.0083 (1.26); 5.9892 (1.14); 5.3498 (0.78); 5.3072 (2.44); 5.2955 (0.47); 52561 (2.50); 52144 (0.85); 4.3867 (0.68); 4.3513 (0.77); 4.0558 (1.12); 4.0379 (3.30); 4.0202 (3.89); 4.0023 (1.32); 3.9942 (1.64); 3.9786 (1.83); 3.9507 (1.81); 3.4231 (1.45); 3.4041 (1.51); 3.3878 (0.75); 3.3800 (2.07); 3.3729 (0.88); 3.3608 (1.84); 3.3521 (1.35); 3.3316 (175.07); 3.3255 (368.38); 3.3020 (5.80); 3.2924 (2.35); 3.2809 (1.22); 3.2728 (1.20); 3.2613 (1.37); 3.2294 (0.57); 2.8611 (0.56); 2.8313 (0.92); 2.8020 (0.50); 2.6754 (0.68); 2.6708 (0.95); 2.6657 (0.72); 2.5409 (0.45); 2.5239 (1.58); 2.5192 (2.43); 2.5099 (58.18); 2.5058 (112.68); 2.5015 (155.66); 2.4973 (109.37); 24932 (54.26); 2.3380 (0.35); 2.3329 (0.66); 2.3284 (0.96); 2.3238 (0.69); 2.2065 (16.00); 2.1274 (0.65); 2.0988 (1.41); 2.0735 (1.62); 1.9885 (14.67); 1.8544 (0.32); 1.8127 (0.63); 1.7909 (0.59); 1.76834 (0.57); 1.5761 (0.60); 1.5693 (0.62); 1.5446 (0.53); 1.5364 (0.52); 1.3156 (2.28); 1.3064 (0.76); 1.2959 (2.67); 1.2866 (0.42); 1.2765 (0.54); 1.2679 (0.40); 1.2465 (0.52); 1.2347 (1.25); 1.2164 (1.37); 1.2125 (1.12); 1.2045 (1.97); 1.2008 (1.68); 1.1923 (5.22); 1.1746 (8.22); 1.1568 (4.07); 0.0081 (1.07); -0.0002 (40.38); -0.0085 (1.27

Pr. I-115, Solvent: dmMeoo-ab, spectrometer: 601.6 MG 8.0888 (16.00); 7.6248 (2.12); 7.6213 (2.33); 7.6124 (3.12); 7.6089 (3.67); 7.6006 (1.05); 7.5972 (1.16); 7.5881 (2.98); 7.5841 (2.00); 7.5752 (3.89); 7.5715 (2.88); 7.5679 (2.59); 7.5653 (3.16); 7.5555 (2.81); 7.5531 (2.87); 7.5431 (1.03); 7.5409 (0.81); 7.5155 (3.68); 7.5131 (3.43); 7.5022 (2.38); 7.4999 (2.40); 7.2695 (1.86); 7.1809 (4.50); 7.1262 (2.06); 7.0924 (2.13); 7.0358 (5.45); 6.9455 (2.45); 6.9122 (4.63); 5.9211 (2.07); 5.9082 (2.35); 5.9026 (2.27); 5.8898 (2.09); 5.7615 (0.61); 5.4546 (1.62); 5.4261 (3.49); 5.37 34 (3.45); 5.3451 (1.58); 4.3629 (1.04); 4.3407 (1.09); 4.0460 (0.46); 4.0341 (1.40); 4.0223 (1.46); 4.0085 (2.03); 3.9900 (2.58); 3.9799 (3.53); 3.9614 (2.80); 3.4798 (2.38); 3.4669 (2.44); 3.4511 (2.28); 3.4383 (2.33); 3.4179 (0.57); 3.4115 (0.98); 3.4053 (0.80); 3.3988 (1.25); 3.3923 (2.11); 3.3861 (1.62); 3.3765 (2.54); 3.3729 (3.09); 3.3501 (682.92); 3.2874 (0.69); 3.2829 (0.79); 3.2632 (1.40); 32443 (0.78); 3.2398 (0.66); 2.8553 (0.65); 2.8512 (0.76); 2.8309 (1.32); 2.8134 (0.75); 2.6211 (0.34); 2.6180 (0.64); 2.6150 (0.89); 2.6120 (0.63); 2.5427 (0.57); 2.5243 (1.73); 2.5213 (2.25); 2.5181 (2.66); 2.5093 (49.30); 2.5063 (106.29); 2.5033 (145.57); 2.5002 (104.57); 2.4972 (45.80); 2.3905 (0.63); 2.3874 (0.85); 2.3844 (0.59); 2.1287 (0.88); 2.1078 (1.07); 2.0879 (0.96); 2.0768 (3.51); 2.0699 (0.97); 1.9900 (6.28); 1.8269 (0.38); 1.8130 (0.82); 1.8068 (0.88); 1.7922 (0.84); 1.7864 (0.79); 1.7724 (0.32); 1.5932 (0.33); 1.5864 (0.39); 1.5727 (0.86); 1.5665 (0.91); 1.5523 (0.89); 1.5464 (0.82); 1.5325 (0.36); 1.3970 (5.56); 1.1863 (1.71); 1.1744 (3.72); 1.1626 (1.78); 0.0053 (0.65); -0.0002 (18.80); -0.0057 0.54

Pr. I-116, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 9.7142 (0.57); 8.0243 (0.95); 8.0108 (16.00); 8.0015 (0.99); 7.4753 (3.15); 7.4709 (3.32); 7.4562 (3.76); 7.4521 (4.22); 7.4455 (2.07); 7.4409 (1.68); 7.4264 (3.75); 7.4222 (3.00); 7.4069 (2.90); 7.4027 (2.14); 7.3404 (2.81); 7.3375 (2.85); 7.3217 (4.16); 7.3189 (4.04); 7.3058 (3.45); 7.2593 (0.45); 7.2434 (4.55); 7.2409 (4.25); 7.2234 (3.87); 7.2206 (3.33); 7.1912 (0.49); 7.1723 (6.62); 7.1578 (3.30); 7.0388 (3.08); 7.0218 (7.49); 6.8992 (6.41); 6.8861 (3.65); 6.537 7 (3.46); 6.5347 (3.36); 6.4945 (5.71); 6.4914 (5.41); 6.37 30 (4.35); 6.3471 (5.41); 6.3299 (2.61); 6.3188 (0.47); 6.3039 (3.24); 6.1157 (5.17); 6.1125 (4.59); 6.0897 (3.85); 6.0867 (3.97); 5.8268 (0.48); 5.7879 (2.39); 5.7683 (2.75); 5.7598 (2.60); 5.7399 (2.34); 5.4500 (1.34); 5.4081 (4.55); 5.3648 (4.75); 53223 (1.35); 4.4962 (0.43); 4.4415 (0.49); 4.4290 (0.48); 4.4129 (0.56); 4.3767 (0.86); 4.3590 (1.64); 4.3266 (1.86); 4.2607 (0.53); 4.2515 (0.48); 4.2251 (0.48); 4.2072 (0.48); 4.2019 (0.46); 4.1467 (0.58); 4.1260 (0.50); 4.1102 (0.51); 4.1014 (0.49); 4.0568 (0.97); 4.0392 (2.86); 4.0212 (2.72); 4.0037 (1.46); 3.9797 (1.89); 3.9442 (1.98); 3.8907 (0.86); 3.8767 (2.78); 3.8484 (3.37); 3.8338 (3.56); 3.8055 (3.20); 3.7907 (0.93); 3.7551 (0.92); 3.7339 (0.90); 3.6687 (1.03); 3.6013 (1.40); 3.5919 (1.28); 3.5846 (1.39); 3.5704 (1.46); 3.5193 (1.79); 3.5074 (1.99); 3.93147 (6446.97); 3.2671 (9.17); 3.2475 (4.70); 3.2378 (2.54); 3.2133 (0.49); 3.0574 (9.61); 2.8691 (1.03); 2.8396 (1.91); 2.8067 (1.02); 2.6743 (2.93); 2.6699 (3.71); 2.6652 (2.74); 2.6420 (0.53); 2.5868 (1.08); 2.5397 (5.24); 2.5095 (221.50); 2.5051 (411.11); 2.5006 (534.78); 2.4962 (367.38); 2.4918 (17412); 2.3319 (2.51); 2.3272 (3.36); 2.3227 (2.36); 2.1340 (1.34); 2.0981 (2.72); 2.0689 (9.82); 1.9867 (10.32); 1.8335 (0.62); 1.8101 (1.26); 1.7765 (1.43); 1.7515 (0.69); 1.6023 (0.68); 1.5728 (1.31); 1.5438 (1.35); 1.5204 (0.64); 1.5119 (0.59); 1.3985 (6.14); 1.2363 (1.73); 1.2147 (0.48); 1.1928 (2.81); 1.1749 (5.83); 1.1572 (2.79); 1.0909 (0.58); 0.8904 (0.85); 0.0077 (1.97); -0.0002 (44.87); -0.0085 1.81

Pr. I-117, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.4153 (0.54); 8.1742 (6.91); 8.0239 (7.41); 7.9994 (0.70); 7.9527 (0.40); 7.5551 (0.56); 7.5470 (0.86); 7.5303 (2.96); 7.5135 (2.36); 7.5087 (3.56); 7.4991 (1.89); 7.4908 (2.87); 7.4847 (1.63); 7.4735 (0.90); 7.4666 (0.58); 7.4352 (3.54); 7.4189 (2.33); 7.4027 (1.32); 7.3966 (1.25); 7.3110 (2.64); 7.1778 (4.52); 7.1659 (2.28); 7.0448 (2.15); 7.0297 (5.07); 6.9060 (5.09); 6.8937 (2.68); 5.7931 (1.08); 5.7721 (1.41); 5.7653 (1.39); 5.7441 (1.27); 57127 (0.34); 5.6906 (0.44); 5.4581 (1.14); 5.4160 (3.69); 5.3717 (3.50); 5.3290 (1.09); 4.6147 (0.79); 4.4908 (3.90); 4.4854 (4.02); 4.3682 (1.23); 4.3337 (1.14); 4.0554 (1.25); 4.0378 (3.81); 4.0201 (3.76); 4.0022 (1.36); 3.9819 (1.02); 3.9493 (1.13); 3.9074 (1.04); 3.8798 (1.28); 3.8639 (1.42); 3.8358 (1.91); 3.7307 (0.32); 3.6999 (0.60); 3.5676 (1.12); 3.4701 (1.08); 3.4498 (0.93); 3.4258 (1.16); 3.4195 (1.09); 3.3903 (2.66); 3.3812 (2.20); 3.3426 (612.09); 3.3381 (484.09); 3.3341 (640.33); 3.3304 (690.13); 3.2625 (3.41); 3.2565 (4.85); 3.2502 (2.58); 3.2389 (1.19); 3.2310 (1.17); 3.1874 (0.34); 2.8904 (2.18); 2.8664 (0.78); 2.8329 (1.32); 2.8033 (0.78); 2.7312 (1.98); 2.6757 (1.46); 2.68706 (1.99); 2.5411 (1.00); 2.5240 (3.32); 2.5059 (233.52); 2.5019 (309.67); 2.4980 (217.79); 2.4547 (0.38); 2.3332 (1.41); 2.3286 (1.94); 2.3236 (1.42); 2.1371 (1.08); 2.0982 (1.97); 2.07391 (2.74); 1.9884 (16.00); 1.8378 (0.49); 1.8098 (0.98); 1.7829 (0.90); 1.7526 (0.38); 1.6122 (0.47); 1.6063 (0.47); 1.5870 (0.72); 1.57 79 (0.93); 1.5563 (0.75); 1.5482 (0.94); 1.5190 (0.40); 1.2347 (0.96); 1.1923 4.20); 1.1746 (8.34); 1.1567 (4.06); 0.0083 (0.67); -0.0002 (21.67

Pr. I-118, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.5178 (3.53); 8.0341 (5.55); 7.5639 (0.84); 7.5467 (1.34); 7.5440 (1.34); 7.4984 (0.51); 7.4847 (0.58); 7, A4786 (0.81); 7.4648 (0.80); 7.4581 (0.44); 7.4446 (0.38); 7.3543 (0.59); 7.3515 (0.57); 7.3309 (0.53); 7.3266 (0.66); 7.3237 (0.65); 7.3031 (0.47); 6.4983 (2.46); 6.2255 (0.51); 6.1970 (0.80); 6.1692 (0.56); 5.7552 (6.90); 5.93525 (0.46); 5.3105 (1.38); 5.2614 (1.38); 5.2189 (0.45); 4.3913 (0.38); 4.3592 (0.41); 4.0380 (0.62); 4.0202 (0.67); 4.0021 (0.47); 3.9620 (0.45); 3.9291 (0.62); 3.9147 (1.07); 3.9064 (16.00); 3.8866 (0.50); 3.8824 (0.57); 3.8572 (0.40); 3.4784 (0.53); 3.4527 (0.55); 3.4369 (0.56); 3.4270 (0.34); 3.4083 (0.71); 3.3980 (0.59); 3.3889 (0.37); 3.3698 (0.40); 3.3589 (0.34); 3.3252 (212.77); 3.3022 (1.96); 3.2738 (0.57); 2.8505 (0.47); 2.8437 (0.47); 2.6709 (0.41); 2.5239 (0.70); 2.5194 (1.07); 2.5058 (43.54); 2.5016 (59.70); 2.4978 (40.52); 2.3283 (0.42); 2.2103 (8.535); 2.1985 (0.66); 2.1520 (0.33); 2.1186 (0.70); 2.0851 (0.41); 2.0735 (1.04); 1.9885 (2.93); 1.1923 (0.76); 1.1745 1.60); 1.1567 (0.78); -0.0002 (1.20

Pr. I-119, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 9.7312 (0.38); 8.7871 (0.53); 8.2193 (0.41); 8.0599 (7.02); 8.0099 (0.53); 7.5082 (1.27); 7.4939 (1.26); 7.4893 (1.87); 7.4802 (0.53); 7.4677 (0.66); 7.4634 (0.97); 7.4592 (1.14); 7.4469 (1.88); 7.4422 (1.45); 7.4241 (3.12); 7.4192 (2.10); 7.4069 (1.42); 7.4016 (1.98); 7.3976 (1.41); 7.3833 (0.61); 7.3795 (0.54); 6.4968 (4.55); 5.9898 (1.04); 5.9703 (1.15); 5.9620 (1.16); 5.9427 (1.04); 5.7554 (5.56); 5.3512 (0.82); 5.3081 (2.39); 5.2562 (2.51); 5.2135 (0.88); 4.3869 (0.72); 4.3541 (0.72); 4.0378 (0.69); 4.0202 (0.790); 4.0027 (0.51); 3.9881 (1.61); 3.9605 (1.70); 3.9449 (1.75); 3.9168 (1.09); 3.7416 (1.41); 3.7234 (4.44); 3.7051 (4.54); 3.6866 (1.46); 3.5545 (0.34); 3.4101 (0.54); 3.4005 (0.44); 3.3896 (0.65); 3.3810 (1.09); 3.3683 (1.68); 3.3493 (1.78); 3.3288 (91.24); 3.3231 (139.97); 3.3052 (2.67); 3.2994 (3.10); 3.2618 (0.97); 3.2329 (0.58); 2.8609 (0.54); 2.8323 (0.93); 2.8042 (0.54); 2.6749 (0.38); 2.6707 (0.51); 2.6660 (0.38); 2.5240 (0.92); 2.5057 (60.28); 2.5015 (82.09); 2.4974 (57.96); 2.3280 (0.55); 2.3236 (0.40); 2.2065 (16.00); 2.1935 (1.00); 2.1337 (0.70); 2.1022 (1.935); 2.0736 (1.47); 1.9885 (3.14); 1.8218 (0.61); 1.8125 (0.62); 1.7913 (0.57); 1.5675 (0.62); 1.5466 (0.55); 1.5369 (0.54); 1.5293 (0.34); 1.5102 (0.47); 1.4447 (4.77); 1.4264 (10.06); 1.4168 (0.51); 1.4080 (4.60); 1.2348 (0.63); 1.1923 (0.82); 1.1745 (1.62); 1.1568 (0.81); -0.0002 (4.36

Pr. I-120, Solvent: dmeoo-avb, spectrometer: 601.6 MHz 8.0198 (5.48); 7.3194 (1.06); 7.3180 (1.29); 7.3151 (1.07); 7.3080 (1.63); 7.3054 (1.80); 7.3025 (1.16); 7.2961 (0.95); 7.2933 (0.52); 7.1382 (1.47); 7.1247 (1.22); 71235 (1.15); 7.0077 (0.80); 7.0069 (0.79); 6.9944 (1.47); 6.9829 (0.71); 6.9819 (0.68); 6.5038 (2.60); 5.8911 (0.78); 5.8792 (0.87); 5.8726 (0.84); 5.8606 (0.79); 5.7645 (7.67); 5.3467 (0.83); 5.3354 (5.10); 5.3183 (1.61); 5.2591 (1.57); 5.2307 (0.79); 4.3737 (0.46); 4.3517 (0.47); 3.9734 (0.43); 3.9510 (0.45); 3.8906 (0.79); 3.8719 (0.93); 3.8622 (1.00); 3.8436 (0.84); 3.3769 (0.36); 3.3705 (0.73); 3.3644 (0.42); 3.3450 (103.48); 3.3214 (1.88); 3.3042 (0.86); 3.2922 (0.89); 3.2758 (1.00); 3.2637 (1.17); 3.2590 (0.65); 3.2397 (0.32); 2.8286 (0.57); 2.6146 (0.41); 2.5240 (0.56); 2.5209 (0.72); 2.5178 (0.74); 2.5088 (21.72); 2.5059 (46.57); 2.5029 (63.46); 2.4999 (46.10); 2.4970 (21.36); 2.3871 (0.38); 2.2038 (10.17); 2.1965 (16.00); 2.1181 (0.37); 2.0938 (0.61); 2.0856 (0.58); 2.0781 (13.21); 2.0691 (0.44); 2.0653 (0.42); 1.8071 (0.35); 1.8012 (0.40); 1.7867 (0.37); 1.7808 (0.34); 1.5628 (0.34); 1.5563 (0.37); 1.5425 (0.35); 1.5360 (0.34); 0.0052 (0.62); -0.0002 (19.68); -0.0057 (0.62

Pr. I-121, Solvent: dmeoo-avb, spectrometer: 601.6 MHz 8.4208 (0.34); 8.2904 (4.51); 8.0377 (0.32); 8.0343 (0.43); 8.0284 (4.77); 7.57 74 (0.48); 7.5679 (1.55); 7.5651 (2.18); 7.5563 (1.37); 7.5540 (1.29); 7.5442 (1.41); 7.5403 (0.81); 7.5318 (0.95); 7.5280 (0.83); 7.5204 (0.52); 7.5165 (0.46); 7.5021 (0.43); 7.4961 (0.46); 7.4922 (0.47); 7.4870 (0.56); 7.4300 (1.20); 7.4272 (0.87); 7.4180 (1.15); 7.4155 (0.90); 7.2714 (0.87); 7.1829 (2.01); 7.1291 (0.96); 7.0944 (0.97); 7.0387 (2.39); 6.9484 (1.10); 6.9146 (2.25); 5.7681 (0.71); 5.7647 (2.93); 5.7548 (0.76); 5.7497 (0.73); 5.7363 (0.67); 5.4561 (0.71); 54275 (1.52); 5.3759 (1.57); 5.3474 (0.74); 4.8002 (0.75); 4.3632 (0.51); 4.3415 (0.55); 4.0453 (1.17); 4.0334 (3.58); 4.0216 (3.61); 4.0098 (1.20); 3.9788 (0.48); 3.9554 (0.51); 3.8997 (0.71); 3.8810 (0.90); 3.8710 (0.93); 3.8524 (0.75); 3.5677 (1.46); 3.4085 (0.40); 3.4020 (0.37); 3.3954 (0.49); 3.3893 (0.83); 3.3829 (0.68); 3.3761 (0.64); 3.3491 (305.79); 3.3257 (1.33); 3.2823 (0.42); 3.2622 (0.66); 3.2433 (0.36); 3.2387 (0.36); 2.8494 (0.35); 2.8286 (0.62); 2.8116 (0.33); 2.8075 (0.92); 2.6208 (0.35); 2.61 78 (0.75); 2.6148 (1.06); 2.6118 (0.77); 2.6087 (0.935); 2.5426 (0.49); 2.5241 (1.68); 2.5211 (2.21); 2.5179 (2.35); 2.5091 (56.57); 2.5061 (122.73); 2.5031 (168.01); 2.5000 (121.58); 2.4970 (55.15); 2.3932 (0.36); 2.3902 (0.78); 2.3872 (1.06); 2.3842 (0.76); 2.3812 (0.33); 2.1266 (0.44); 2.1050 (0.52); 2.0959 (0.53); 2.0876 (0.53); 2.0781 (0.91); 2.0663 (0.53); 1.9904 (16.00); 1.8077 (0.43); 1.7874 (0.42); 1.5742 (0.95); 1.5676 (0.41); 1.5541 (0.39); 1.5473 (0.39); 1.2336 (0.72); 1.1859 (4.38); 1.1740 (8.64); 1.1622 (4.25); 0.0052 (0.76); -0.0002 (25.14); -0.0058 0.75

Pr. I-122, Solvent: dmeoo-avb, spectrometer: 601.6 MHz 9.9401 (0.38); 9.9252 (0.39); 9.8193 (2.92); 8.6576 (4.57); 8.4591 (0.74); 8.4438 (0.73); 8.3170 (7.05); 8.1557 (0.36); 8.0449 (15.39); 8.0351 (5.12); 7.7017 (4.54); 7.6882 (5.15); 7.6339 (0.37); 7.6229 (0.45); 7.6048 (0.41); 7.6022 (0.36); 7.5949 (3.39); 7.5933 (3.42); 7.5816 (3.75); 7.5800 (3.68); 7.5546 (0.33); 7.5232 (6.63); 7.4850 (3.87); 7.4716 (3.41); 7.4027 (4.07); 7.4003 (4.43); 7.3897 (4.94); 7.3873 (5.24); 7.3630 (0.45); 7.3607 (0.44); 7.3476 (2.74); 7.3451 (1.98); 7.3352 (4.04); 7.3327 (3.12); 7.3220 (3.83); 7.3196 (3.77); 7.3088 (1.03); 7.2766 (0.83); 7.2745 (0.79); 7.2641 (1.24); 72536 (2.45); 7.2520 (2.78); 72411 (3.46); 7.2394 (3.45); 7.2286 (1.60); 7.2268 (1.56); 7.1848 (2.98); 7.1652 (2.21); 7.0923 (6.90); 7.0735 (5.00); 6.9999 (3.32); 6.9819 (2.48); 6.0322 (0.77); 6.0200 (0.87); 6.0141 (0.84); 6.0017 (0.76); 5.9025 (2.16); 5.8897 (2.44); 5.8843 (2.35); 5.8715 (2.15); 5.7632 (6.72); 4.1716 (3.94); 4.1493 (4.05); 4.0456 (1.21); 4.0338 (3.56); 4.0219 (3.60); 4.0101 (1.20); 3.9429 (0.94); 3.9369 (2.34); 3.9246 (1.09); 3.9186 (2.85); 3.9144 (1.26); 3.9082 (2.98); 3.8960 (1.01); 3.8899 (2.45); 3.4779 (0.36); 3.4468 (0.45); 3.4377 (0.48); 3.4260 (0.69); 3.4136 (1.01); 3.4027 (1.82); 3.3902 (4.64); 3.3679 (2166.76); 3.3528 (5.87); 3.3442 (8.02); 3.3380 (2.40); 3.3317 (2.97); 3.3250 (1.69); 3.3190 (1.03); 3.9125 (1.46); 3.3064 (0.74); 3.2649 (0.86); 3.2525 (0.94); 3.2442 (2.65); 3.2361 (1.11); 3.2315 (2.69); 3.2240 (0.96); 32154 (2.51); 3.2028 (2.42); 3.0459 (2.46); 3.0262 (4.72); 3.0068 (2.50); 2.6221 (0.58); 2.6191 (1.24); 2.6161 (1.73); 2.6131 (1.24); 2.6101 (0.56); 2.5438 (1.05); 2.5254 (3.28); 2.5223 (4.26); 2.5192 (4.75); 2.5104 (89.48); 2.5074 (193.26); 2.5044 (261.74); 2.5013 (184.86); 2.4983 (81.53); 2.3946 (0.49); 2.3915 (1.13); 2.3885 (1.59); 2.3855 (1.11); 2.3825 (0.47); 2.2140 (0.58); 2.0962 (3.16); 2.0934 (3.26); 2.0777 (5.56); 1.9906 (16.00); 1.7014 (1.05); 1.6950 (1.29); 1.6806 (2.77); 1.6751 (3.05); 1.6604 (2.92); 1.6549 (2.71); 1.6407 (1.14); 1.6344 (0.93); 1.2347 (0.58); 1.1862 (4.33); 1.1743 (8.83); 1.1625 4.24); 0.8536 (0.33); -0.0002 (8.27

Pr. I-123, Solvent: dmeoo-avb, spectrometer: 601.6 MHz 9.9420 (0.58); 9.9242 (0.60); 9.8166 (2.24); 8.4616 (1.41); 8.4439 (1.39); 8.3185 (4.52); 8.3156 (4.39); 8.3017 (0.34); 8.0421 (9.51); 8.0362 (0.51); 8.031 7 (3.28); 7.9528 (0.44); 7.7179 (2.73); 7.7046 (3.41); 7.6630 (0.36); 7.6040 (2.87); 7.5933 (3.57); 7.5819 (2.41); 7.5080 (4.44); 7.3985 (2.49); 7.3961 (2.75); 7.3856 (3.04); 7.3832 (3.27); 7.3468 (1.67); 7.3443 (1.24); 7.3343 (2.56); 7.3318 (1.98); 7.3212 (2.32); 7.3090 (0.56); 7.2746 (0.52); 72724 (0.51); 7.2623 (0.94); 7.2501 (2.07); 7.2442 (1.84); 72393 (2.38); 7.2377 (2.30); 7.2268 (1.10); 7.2250 (1.06); 7.1867 (1.90); 7.1535 (3.62); 7.0941 (4.28); 7.0813 (0.45); 7.0628 (1.75); 7.0245 (0.39); 7.0017 (2.08); 6.0316 (0.47); 6.0192 (0.54); 6.0133 (0.53); 6.0011 (0.48); 5.9010 (1.33); 5.8883 (1.50); 5.8828 (1.49); 5.8700 (1.34); 5.7644 (1.27); 4.6529 (0.52); 4.4397 (1.11); 4.4174 (1.16); 4.0740 (1.07); 4.0455 (2.61); 4.0336 (3.72); 4.0216 (5.82); 4.0099 (1.45); 3.9909 (3.45); 3.9632 (1.12); 3.9369 (0.61); 3.9302 (1.49); 3.9186 (0.69); 3.9119 (1.83); 3.9084 (0.88); 3.9014 (1.85); 3.8900 (0.63); 3.8832 (1.54); 3.3987 (0.66); 3.3788 (3.63); 3.3539 (152423); 3.3354 (2.56); 3.3304 (8.73); 3.3218 (0.84); 3.3169 (0.51); 3.2677 (0.92); 3.2559 (0.99); 3.2478 (1.69); 3.2442 (1.64); 3.2369 (1.88); 3.2273 (1.55); 3.2242 (2.38); 3.2152 (0.74); 3.2081 (1.64); 3.1938 (3.25); 2.8905 (3.89); 2.8019 (0.78); 2.7825 (1.42); 2.7630 (0.79); 2.7309 (3.00); 2.7302 (2.94); 2.6211 (0.86); 2.6182 (1.82); 2.6151 (2.50); 2.6121 (1.79); 2.6091 (0.82); 2.5429 (1.59); 2.5245 (5.66); 2.5214 (7.41); 2.5182 (8.38); 2.5094 (129.99); 2.5064 (279.75); 2.5034 (381.53); 2.5004 (268.53); 2.4973 (120.33); 2.4772 (0.34); 2.3936 (0.80); 2.3906 (1.74); 2.3875 (2.38); 2.3845 (1.67); 2.3816 (0.73); 2.0961 (1.12); 2.0781 (2.86); 2.0731 (1.93); 2.0481 (1.08); 2.0072 (0.39); 1.9905 (16.00); 1.7446 (0.33); 1.7380 (0.42); 1.7239 (0.86); 1.7180 (0.94); 1.7036 (0.88); 1.6979 (0.85); 1.6834 (0.36); 1.5627 (0.937); 1.5431 (0.87); 1.5281 (0.83); 1.5225 (0.80); 1.5082 (0.33); 1.2357 (1.01); 1.1860 (4.35); 1.1741 (8.68); 1.1623 (4.34); 0.8536 (0.59); 0.0053 (0.41); -0.0002 (12.47); -0.0057 (0.38

Pr. I-124, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0500 (3.06); 7.5174 (0.60); 7.5005 (0.90); 7.4702 (0.52); 7.4658 (0.63); 7.4549 (1.63); 7.4511 (2.12); 7, A4374 (0.38); 7.4263 (0.62); 7.4200 (0.46); 7.4077 (0.51); 7.4009 (0.35); 7.3083 (0.52); 7.1750 (1.19); 7.1586 (0.58); 7.0419 (0.65); 7.0225 (1.31); 6.8999 (1.31); 6.8866 (0.66); 6.0101 (0.47); 5.9905 (0.56); 5.9823 (0.55); 5.9626 (0.48); 5.7459 (3.60); 5.4101 (0.93); 5.3672 (0.91); 3.9989 (0.55); 3.9711 (0.73); 3.9555 (0.84); 3.9277 (0.56); 3.5809 (0.40); 3.5471 (9.00); 3.4187 (16.00); 3.93672 (1.36); 3.93590 (0.78); 3.3477 (0.98); 3.3236 (0.69); 3.3041 (0.77); 3.2665 (0.43); 2.8410 (0.38); 2.5060 (9.35); 2.5016 12.12); 2.4973 (8.82); 2.3280 (0.91); 2.1013 (0.55); 2.0852 (0.37); 2.0694 (0.40); -0.0002 (0.52

Pr. I-125, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 18.5768 (0.33); 8.0926 (0.46); 8.0825 (10.10); 7.6296 (1.043; 7.6226 (1.09); 7.6121 (1.83); 7.6059 (2.60); 7.5893 (2.11); 7.5832 (1.47) ; 7.5708 (4.47); 7.5646 (3.68); 7.5522 (1.58); 7.5482 (1.78); 7.5337 (0.71); 7.5144 ( 2.34); 7.5098 (2.12); 7.4951 (1.09); 7.4911 (1.38); 6.4974 (4.66); 5.9272 (1.14); 5.9079 (1.40); 5.8997 (1.43); 5.8800 (1.24); 5.7553 (8.35); 5.3507 (0.89); 5.3087 (2 .58); 5.2550 (2.52); 5.2125 (0.85); 4.4054 (0.33); 4.3886 (0.80); 4.3780 (0.62); 4 .3580 (0.76); 4.0561 (0.37); 4.0378 (0.99); 4.0200 (1.81); 3.9909 (1.89); 3.9757 (1, 95); 3.9483 (1.77); 3.4870 (1.44); 3.4676 (1.61); 3.4435 (1.36); 3.4248 (1.61); 3, 4155 (0.64); 3.4064 (0.50); 3.3946 (0.68); 3.3870 (1.16); 3.3775 (0.80); 3.3583 (0.86 ); 3.3303 (215.63); 3.3271 (215.72); 3.3248 (302.68); 3.3019 (4.46); 3.2631 (1.05); 3.2312 (0.60); 3.2202 (0.33); 2.8636 (0.62); 2.8310 (0.92); 2.8056 (0.56); 2.7989 (0.47) ; 2.7835 (0.36); 2.6759 (0.77); 2.6706 (1.03); 2.5А411 (0.48); 2.5239 (1.40); 2.5194 ( 2.24); 2.5101 (54.72); 2.5060 (106.67); 2.5017 (148.94); 24974 (104.46 ); 2.4932 (52.53); 2.3285 (1.01); 2.3240 (0.80); 2.2074 (16.00); 2.1320 (0.73); 2.0975 (1.39); 2.0736 (2.07); 1.9885 (4.25); 1.8523 (0.39); 1.8480 (0.38); 1.8441 (0.38); 1.8228 (0.66); 1.8139 (0.77); 1.7908 (0.66); 1.7817 (0.58); 1.6097 (0.36); 1.6022 (0.33); 1.5799 (0.57); 1.5702 (0.69); 1.5445 (0.55); 1.5404 (0.60); 1.5102 (0.40); 1.2355 (0.82); 1.1923 (1.18); 1.1746 (2.20); 1.1569 (1.19); -0.0002 8.87); -0.0084 (0.34

Pr. I-127, Solvent: dmMeoo-ab, spectrometer: 601.6 MG 8.0548 (6.34); 8.0193 (3.69); 7.4264 (0.48); 7.4208 (0.45); 7.4109 (1.44); 7.4037 (0.88); 7.3986 (1.03); 7.3950 (2.25); 7.3908 (1.25); 7.3813 (3.55); 7.3745 (2.29); 7.3701 (2.49); 7.3672 (2.22); 7.3585 (0.65); 7.2705 (1.37); 7.1819 (3.17); 7.1278 (2.42); 7.1206 (1.33); 7.1181 (1.10); 7.1133 (1.61); 7.1071 (0.67); 7.1010 (0.81); 7.0934 (1.56); 7.0367 (3.84); 6.9464 (1.77); 6.9116 (3.39); 5.7765 (0.62); 5.7617 (1.33); 5.7577 (0.75); 5.7425 (0.66); 5.6326 (1.07); 5.6189 (1.23); 5.6145 (1.23); 5.6007 (1.06); 5.4548 (1.23); 5.4261 (2.67); 5.3740 (2.61); 5.3454 (1.19); 4.3622 (0.83); 4.3401 (0.86); 4.0458 (0.88); 4.0339 (2.59); 4.0221 (2.59); 4.0103 (0.89); 3.9774 (0.77); 3.9544 (0.86); 3.8737 (0.57); 3.8547 (0.68); 3.8453 (0.73); 3.8254 (1.20); 3.8067 (1.08); 3.7959 (1.19); 3.7777 (0.98); 3.5507 (15.90); 3.5376 (0.47); 3.5128 (9.57); 3.5050 (0.42); 3.5000 (0.52); 3.4054 (2.20); 3.3918 (1.87); 3.3874 (1.65); 3.3810 (1.02); 3.3764 (2.04); 3.3623 (2.32); 3.3434 (478.54); 3.3198 (10.36); 3.2843 (0.57); 3.2617 (0.93); 3.2413 (0.58); 3.0887 (0.52); 3.0811 (16.00); 3.0468 (9.18); 3.0291 (0.47); 2.8531 (0.54); 2.8485 (0.50); 2.8319 (1.03); 2.8111 (0.61); 2.6174 (0.61); 2.6144 (0.87); 2.6114 (0.63); 2.5422 (0.37); 2.5237 (1.10); 2.5206 (1.42); 2.5176 (1.51); 2.5086 (46.49); 2.5056 (100.97); 2.5026 (139.60); 2.4996 (101.65); 24967 (47.64); 2.3898 (0.60); 2.3868 (0.85); 2.3838 (0.61); 2.1284 (0.71); 2.1069 (0.84); 2.0897 (0.81); 2.0768 (1.64); 2.0692 (0.84); 1.9898 (11.43); 1.8081 (0.67); 1.7887 (0.63); 1.5692 (0.67); 1.5622 (0.51); 1.5488 (0.66); 1.2343 (0.39); 1.1861 (3.07); 1.1742 (6.02); 1.1624 (3.04); 0.0052 (2.23); - 0.0002 (71.69); -0.0057 (2.41

Pr. I-128, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0124 (5.51); 7.3274 (3.17); 7.3058 (3.95); 7.1743 (2.21); 7.1589 (1.02); 7.0409 (1.11); 7.0231 (2.41); 6.9568 (3.78); 6.9349 (3.31); 6.8999 (2.19); 6.8872 (1.18); 5.7461 (6.04); 5.6916 (0.82); 5.6700 (1.08); 5.6644 (1.00); 5.6428 (0.81); 5.4516 (0.49); 5.4091 (1.69); 5.3675 (1.62); 5.3249 (0.45); 4.7993 (8.53); 4.3640 (0.54); 4.3288 (0.56); 4.0392 (0.52); 4.0215 (0.52); 3.9834 (0.55); 3.9486 (0.57); 3.8498 (0.90); 3.8226 (1.03); 3.8068 (1.17); 3.7800 (1.00); 3.6953 (16.00); 3.4708 (0.33); 3.4544 (0.42); 3.4160 (0.99); 3.3810 (2.52); 3.3595 (3.52); 3.3123 (625.31); 3.2897 (8.06); 3.2419 (0.78); 2.8734 (0.36); 2.8432 (0.65); 2.8150 (0.36); 2.6738 (0.36); 2.6694 (0.45); 2.6651 (0.33); 2.5394 (0.79); 2.5092 (28.20); 2.5049 (51.00); 2.5005 (65.41); 2.4962 (46.17); 2.3271 (0.44); 2.3227 (0.33); 2.1396 (0.49); 2.1041 (0.98); 2.0689 (1.19); 1.9868 (2.00); 1.8129 (0.44); 1.7911 (0.43); 1.5912 (0.41); 1.5822 (0.44); 1.5614 (0.42); 1.5526 (0.40); 1.1927 (0.55); 1.1749 (1.10); 1.1571 (0.52); -0.0002 (3.03

Pr. I-129, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 7.9138 (1.20); 7.9102 (1.40); 7.9030 (1.88); 7.8923 (1.90); 7.8884 (1.69); 7.8742 (9.96); 7.7763 (1.95); 7.71527 (2.10); 7.5633 (2.67); 7.5579 (2.02); 7.5494 (3.92); 7.5433 (2.12); 7.5353 (3.38); 7.5309 (3.32); 7.5250 (2.68); 7.5086 (2.53); 7.5057 (2.88); 7.5010 (1.63); 7.4967 (1.28); 7.4814 (2.66); 7.4757 (1.56); 7.4621 (2.01); 7.4579 (1.71); 7.3801 (2.18); 7.3642 (6.07); 7.3445 (4.06); 7.3263 (0.37); 7.3191 (0.42); 7.3106 (1.93); 7.3005 (0.68); 71772 (3.99); 7.1601 (2.03); 7.0439 (1.95); 7.0240 (4.47); 6.9028 (4.17); 6.8882 (2.31); 5.8647 (1.45); 5.8447 (1.78); 5.8359 (1.71); 5.8157 (1.49); 5.7455 (16.00); 5.4551 (0.84); 5.4122 (2.96); 5.3672 (2.99); 5.3250 (0.687); 4.3504 (0.92); 4.3176 (0.98); 4.0398 (0.45); 4.0220 (0.45); 3.9717 (0.87); 3.9378 (0.96); 3.8683 (1.38); 3.8393 (1.63); 3.8252 (1.91); 3.7962 (1.58); 3.4548 (1.81); 3.4348 (1.86); 3.4116 (1.71); 3.3916 (1.86); 3.3221 (190.96); 3.2634 (2.04); 3.2332 (1.10); 3.1931 (0.34); 2.8672 (0.70); 2.8385 (1.21); 2.8098 (0.71); 2.5105 (12.11); 2.5063 (22.74); 2.5018 (29.97); 2.4975 (21.44); 2.4932 (10.80); 2.0944 (0.89); 2.0691 (1.85); 2.0625 (1.78); 2.0271 (1.01); 1.9873 (1.95); 1.7935 (0.38); 1.7660 (0.81); 1.7423 (0.75); 1.7141 (0.33); 1.5670 (0.38); 1.5456 (0.74); 1.5366 (0.79); 1.5156 (0.76); 1.5076 (0.71); 1.2360 (0.42); 1.1932 (0.67); 1.1798 (0.42); 1.1754 (1.13); 1.1576 (0.57); -0.0002 (0.53

Pr. I-130, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0644 (1.80); 8.0598 (2.00); 8.0448 (3.47); 8.0408 (3.44); 8.0260 (1.82); 8.0217 (1.70); 7.8987 (0.54); 7.8832 (16.00); 7.8343 (0.34); 7.7476 (0.97); 7.7298 (1.88); 7.7165 (1.86); 7.7000 (1.07); 7.6955 (1.00); 7.5325 (0.63); 7.5204 (2.786); 7.5158 (3.44); 7.4963 (5.22); 7.4756 (4.17); 7.4563 (3.32); 7.4522 (2.63); 7.4390 (0.33); 7.3783 (4.35); 7.3721 (6.20); 7.3692 (6.13); 7.3618 (7.19); 7.3521 (4.59); 7.3492 (4.23); 7.3431 (4.47); 7.3311 (4.22); 7.3117 (7.76); 7.2926 (2.72); 7.2815 (0.77); 7.2625 (0.39); 7.1747 (6.30); 7.1587 (3.08); 7.0414 (3.18); 7.0225 (7.05); 6.9001 (6.62); 6.8867 (3.61); 5.8667 (2.37); 5.8470 (2.82); 5.8383 (2.72); 5.8184 (2.37); 5.4532 (1.40); 5.4108 (4.66); 5.3652 (4.79); 5.3234 (1.41); 4.3498 (1.59); 4.3186 (1.70); 4.0567 (1.32); 4.0391 (3.52); 4.0213 (3.60); 4.0134 (0.46); 4.0035 (1.36); 3.9706 (1.62); 3.9363 (1.66); 3.8763 (2.44); 3.8475 (2.90); 3.8391 (3.25); 3.8046 (2.73); 3.6580 (0.32); 3.6542 (0.36); 3.6153 (0.44); 3.5885 (0.41); 3.5758 (0.43); 3.5619 (0.49); 3.5578 (0.47); 3.5243 (0.56); 3.5174 (0.56); 3.5138 (0.61); 3.4942 (0.69); 3.4856 (0.74); 3.4128 (4.20); 3.3931 (4.96); 3.3693 (6.11); 3.3498 (8.85); 3.3075 (1451.40); 3.2842 (19.84); 3.2318 (1.44); 2.8652 (1.14); 2.8362 (1.91); 2.8096 (1.17); 2.68737 (1.22); 2.6691 (1.54); 2.6647 (1.18); 2.6165 (0.40); 2.5394 (2.43); 2.5089 (93.38); 2.5046 (169.77); 2.5002 (218.38); 24958 (152.29); 2.4915 (73.85); 2.3310 (0.94); 2.3267 (1.91); 2.3220 (0.92); 2.1034 (1.44); 2.0692 (4.78); 2.0360 (1.56); 1.9867 (14.75); 1.8012 (0.54); 1.7807 (1.26); 1.7738 (1.27); 1.7493 (1.17); 1.7194 (0.52); 1.5832 (0.55); 1.5712 (0.59); 1.5433 (1.23); 1.5218 (1.16); 1.4921 (0.48); 1.3984 (2.30); 1.2379 (0.57); 1.1927 (4.01); 1.1750 (7.91); 1.1571 (3.88); 1.1086 (0.43); 1.0910 (0.87); 1.0735 (0.44); 0.8902 (0.39); -0.0002 (4.36

Pr. I-131, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0886 (6.27); 8.0859 (7.25); 8.0680 (7.92); 8.0649 (6.52); 7.8910 (16.00); 7.7165 (1.77); 7.6979 (3.95); 7.6792 (2.38); 7.5279 (6.01); 7.5236 (3.47); 7.5158 (4.59); 7.5075 (8.78); 7.4969 (5.04); 7.4888 (5.40); 7.4715 (3.92); 7.4675 (2.77); 74521 (3.01); 7.4479 (2.43); 7.3715 (3.19); 7.3532 (10.40); 7.3339 (6.09); 7.3086 (2.62); 7.1753 (5.91); 7.1591 (2.88); 7.0420 (2.88); 7.0230 (6.71); 6.9008 (6.02); 6.8871 (3.32); 5.8624 (2.21); 5.8426 (2.73); 5.8341 (2.57); 5.8140 (2.18); 5.4524 (1.28); 5.4100 (4.41); 5.3641 (4.37); 53222 (1.24); 4.3469 (1.43); 4.3139 (1.52); 4.0570 (1.20); 4.0391 (3.28); 4.0213 (3.26); 4.0034 (1.27); 3.9679 (1.39); 3.9343 (1.49); 3.9056 (0.33); 3.8667 (2.29); 3.8379 (2.72); 3.8235 (3.15); 3.7949 (2.58); 3.6089 (0.37); 3.6033 (0.34); 3.5957 (0.35); 3.5515 (0.41); 3.5253 (0.46); 3.4353 (3.62); 3.4154 (3.78); 3.3921 (4.06); 3.3723 (5.34); 3.3655 (4.62); 3.3114 (169441); 3.2880 (19.13); 3.2645 (2.94); 3.2295 (1.32); 2.8636 (0.99); 2.8367 (1.72); 2.8061 (1.08); 2.6738 (0.93); 2.6694 (1.24); 2.6650 (0.97); 2.5395 (1.96); 2.5092 (73.15); 2.5048 (135.80); 2.5003 (177.60); 2.4959 (124.39); 2.4916 (60.74); 2.3365 (0.45); 2.3315 (0.78); 2.3270 (1.12); 2.3225 (0.82); 2.0951 (1.28); 2.0690 (4.13); 2.0304 (1.47); 1.9867 (14.27); 1.7979 (0.54); 1.7685 (1.15); 1.7455 (1.03); 1.7166 (0.42); 1.5795 (0.48); 1.5693 (0.54); 1.5407 (1.11); 1.5179 (1.09); 1.5093 (1.06); 1.4895 (0.45); 1.4827 (0.43); 1.3983 1.22); 1.2359 (0.45); 1.1927 (3.86); 1.1 749 (7.82); 1.1571 (3.79); -0.0002 (0.88

Pr. I-132, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.1395 (3.85); 8.1340 (1.82); 8.1257 (4.36); 8.1171 (4.14); 8.1091 (1.79); 8.1034 (3.63); 8.0207 (1.17); 8.0155 (0.51); 8.0067 (1.38); 7.9984 (1.34); 7.9903 (0.50); 7.9843 (1.26); 7.8725 (10.97); 7.5159 (2.72); 7.4969 (3.48); 7.4887 (1.48); 7.4735 (3.10); 7.4692 (2.38); 7.4541 (2.46); 7.4498 (1.95); 7.3716 (2.61); 7.3530 (8.05); 7.3406 (2.27); 7.3333 (5.61); 7.3299 (6.06); 7.3242 (2.26); 7.3184 (3.32); 7.3072 (9.21); 7.2962 (1.82); 7.2853 (3.67); 7.1731 (4.77); 7.1592 (2.37); 7.0398 (2.37); 7.0231 (5.42); 6.9011 (4.75); 6.8871 (2.67); 5.8543 (1.76); 5.8346 (2.13); 5.8252 (1.97); 5.8056 (1.76); 5.7455 (1.19); 5.4490 (1.03); 5.4058 (3.54); 5.3663 (3.56); 5.3237 (0.94); 4.3510 (1.18); 4.3183 (1.24); 4.0570 (1.40); 4.0392 (3.76); 4.0214 (3.79); 4.0036 (1.35); 3.9727 (1.17); 3.9371 (1.25); 3.8582 (1.88); 3.8293 (2.14); 3.8153 (2.43); 3.7862 (2.12); 3.7318 (0.39); 3.6978 (0.39); 3.6632 (0.43); 3.6302 (0.51); 3.6140 (0.49); 3.5997 (0.56); 3.57 74 (0.64); 3.5351 (0.77); 3.5092 (0.94); 3.4291 (4.00); 3.4094 (4.73); 3.3858 (5.96); 3.3659 (9.82); 3.3196 (2619.83); 3.2602 (3.59); 3.2303 (1.57); 3.1546 (0.33); 2.8620 (0.86); 2.8356 (1.41); 2.8053 (0.77); 2.6749 (1.05); 2.6699 (1.41); 2.6659 (1.10); 2.5400 (2.12); 2.5099 (83.96); 2.5055 (156.08); 2.5011 (203.95); 24967 (142.32); 2.4923 (69.27); 2.3324 (1.00); 2.3276 (1.26); 2.3232 (1.02); 2.0912 (1.06); 2.0689 (5.92); 2.0241 (1.18); 1.9868 (16.00); 1.7709 (0.92); 1.7445 (0.91); 1.7131 (0.97); 1.5647 (0.44); 1.5438 (0.91); 1.5349 (0.93); 1.5136 (0.88); 1.5065 (0.84); 1.4743 (0.36); 1.3983 (3.47); 1.2358 (0.81); 1.1929 (4.49); 1.1751 (8.70); 1.1573 (4.44); -0.0002 (3.31

Pr. I-134, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0174 (16.00); 7.9657 (3.69); 7.9630 (3.81); 7.9465 (4.03); 7.9437 (3.86); 7.6191 (1.48); 7.5990 (3.97); 7.5813 (2.88); 7.5442 (4.84); 7.5268 (2.66); 7.4489 (2.36); 7.4300 (3.64); 7.4114 (1.86); 7.4083 (1.67); 7.3026 (2.72); 7.2326 (0.32); 7.1694 (6.24); 7.1569 (2.99); 7.0361 (3.12); 7.0209 (7.04); 7.0043 (0.46); 6.8967 (6.40); 6.8849 (3.50); 6.4046 (2.24); 6.3885 (2.58); 6.37 70 (2.35); 6.3608 (2.18); 5.7463 (6.30); 5.4444 (1.36); 5.4023 (4.65); 5.3615 (4.75); 5.3187 (1.28); 4.93523 (1.63); 4.3164 (1.69); 4.1492 (0.92); 4.0945 (0.33); 4.0840 (0.37); 4.0735 (0.37); 4.0573 (0.55); 4.0392 (1.42); 4.0330 (2.60); 4.0215 (1.19); 4.0052 (3.01); 3.9890 (3.35); 3.9613 (3.75); 3.9363 (1.77); 3.8469 (0.38); 3.8414 (0.43); 3.8267 (0.86); 3.8094 (0.43); 3.7632 (0.45); 3.7463 (0.53); 3.7253 (0.52); 3.6722 (0.62); 3.6667 (0.62); 3.6556 (0.63); 3.6392 (0.68); 3.6091 (0.80); 3.5867 (0.79); 3.5411 (1.14); 3.5031 (1.44); 3.39128 (598.65); 32277 (3.65); 3.2118 (4.74); 3.1955 (4.05); 3.1678 (3.43); 3.1519 (3.18); 3.1347 (0.65); 3.1197 (0.53); 3.1033 (0.43); 3.0799 (0.39); 3.0684 (0.33); 2.8558 (1.10); 2.8274 (1.90); 2.7990 (1.11); 2.6912 (0.34); 2.68743 (1.28); 2.6695 (1.62); 2.6655 (1.18); 2.6086 (0.53); 2.5094 (96.28); 2.5051 (173.35); 2.5007 (221.06); 2.4964 (153.60); 2.4921 (74.80); 2.3317 (1.01); 2.3276 (1.47); 2.3233 (1.03); 2.1203 (1.40); 2.0849 (3.02); 2.0693 (2.53); 2.0529 (1.59); 1.9869 (3.44); 1.8305 (0.62); 1.8033 (1.25); 1.7797 (1.18); 1.7488 (0.47); 1.5895 (0.65); 1.5680 (1.22); 1.5602 (1.91); 1.5383 (1.12); 1.5298 (1.20); 1.5096 (0.49); 1.2366 (0.74); 1.1930 (0.95); 1.1751 (1.85); 1.1573 (0.94); 0.8900 (0.34); -0.0002 (3.87

Pr. I-195, Solvent: dmeoo-a6, spectrometer: 399.95 MHz 14.1260 (0.72); 13.3817 (0.69); 13.2857 (0.72); 13.2809 (0.75); 15.2757 (0.81); 13.2498 (0.80); 13.2340 (0.87); 13.2060 (0.89); 13.1986 (0.71); 13.1415 (0.71); 13.1068 (0.85); 13.0719 (0.83); 7.9737 (9.56); 7.9710 (9.75); 7.9540 (10.25); 7.6693 (0.72); 7.6418 (3.95); 7.6247 (9.46); 7.6065 (7.06); 7.5511 (12.31); 7.5330 (7.43); 7.4669 (6.15); 7.4479 (9.82); 7.4289 (4.69); 7.4079 (0.98); 7.2858 (6.28); 7.2747 (1.95); 7.1723 (1.85); 7.1524 (15.53); 7.0672 (0.76); 7.0363 (2.76); 7.0194 (8.67); 7.0122 (16.00); 6.8916 (15.78); 6.8764 (7.57); 6.3940 (5.83); 6.3769 (6.84); 6.3655 (6.25); 6.3495 (5.62); 5.7468 (8.87); 5.4271 (3.18); 5.3817 (10.99); 5.3430 (12.11); 5.2988 (3.06); 5.0884 (1.92); 4.9964 (0.72); 4.9415 (0.93); 4.7184 (0.72); 4.6263 (0.74); 4.6019 (0.76); 4.5397 (0.73); 4.4952 (0.84); 4.4553 (0.81); 4.4359 (0.85); 4.3845 (0.92); 4.3208 (4.26); 4.2862 (4.44); 4,2252 (0.91); 4.1930 (0.87); 4.1727 (0.98); 4.1520 (1.20); 4.1248 (1.18); 4.1056 (5.86); 4.0866 (1.95); 4.0775 (7.13); 4.0610 (8.05); 4.0393 (4.48); 4.0391 (6.79); 4.0214 (3.68); 4.0032 (2.02); 3.9821 (1.24); 3.9753 (1.40); 3.9628 (1.76); 3.9426 (4.25); 3.9062 (4.58); 3.8734 (1.77); 3.8598 (1.42); 3.8361 (1.34); 3.8235 (1.40); 3.8181 (1.91); 3.7885 (1.54); 3.7514 (1.59); 3.7054 (1.76); 3.6326 (1.94); 3.5783 (2.59); 3.5132 (3.42); 3.4595 (5.08); 3.3076 (3416.56); 3.2430 (13.37); 3.2263 (11.33); 3.1982 (8.45); 3.1820 (8.49); 2.8288 (2.75); 2.1949 (4.89); 2.7662 (2.92); 2.7231 (0.81); 2.7102 (0.99); 2.6695 (5.50); 2.5049 (610.95); 2.5005 (758.75); 2.4964 (528.92); 2.3272 (4.73); 2.0696 (7.43); 2.0389 (7.07); 2.0087 (4.19); 1.9869 (12.23); 1.9079 (0.98); 1.7854 (1.53); 1.7544 (3.28); 1.7328 (2.93); 1.7054 (1.28); 1.6545 (0.74); 1.5507 (1.66); 1.5421 (1.62); 1.5243 (3.67); 1.5209 (3.42); 1.5011 (2.91); 1.4719 (1.48); 1.3983 (1.69); 1.3005 (0.74); 1.2369 (4.63); 1.2242 (1.08); 1.2093 (0.81); 1.1928 (3.20); 1.1752 (6.27); 1.1571 (3.19); 0.8687 (0.74); 0.8543 (0.87); -0.0002 (67.74); -0.9033 (0.78); -2.0576 (0.69

Pr. I-136, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0311 (0.54); 8.0194 (9.83); 7.8488 (1.24); 7.8349 (2.58); 7.8208 (1.28); 7.4052 (2.02); 7.4012 (2.47); 7.3860 (2.65); 7.3821 (3.30); 7.37 70 (1.36); 7.3726 (1.08); 7.3577 (2.44); 7.3534 (2.04); 7.3382 (2.02); 7.3340 (1.60); 7.3131 (2.04); 72641 (1.95); 7.2617 (2.08); 7.2453 (2.87); 7.2429 (2.92); 72266 (1.20); 7.2240 (1.17); 7.1799 (4.79); 7.1718 (2.44); 7.1584 (3.24); 7.1561 (2.99); 7.1383 (2.75); 7.0468 (2.32); 7.0358 (5.55); 6.9116 (4.58); 6.9000 (2.67); 5.7838 (1.53); 5.7643 (1.76); 5.7560 (1.68); 5.7363 (1.46); 5.4613 (1.16); 5.4186 (3.62); 5.3760 (3.63); 5.3332 (1.17); 4.3626 (1.05); 4.3302 (1.09); 3.9785 (0.97); 3.9442 (1.07); 3.8921 (1.58); 3.8641 (1.85); 3.8489 (2.13); 3.8209 (1.74); 3.4076 (0.67); 3.3981 (0.56); 3.3874 (0.97); 3.3785 (1.70); 3.3695 (1.22); 3.3598 (1.40); 3.3424 (364.53); 3.3185 (4.84); 3.2982 (2.24); 3.2886 (1.13); 3.2789 (2.10); 3.2552 (2.81); 3.2356 (1.90); 3.1964 (0.34); 3.1198 (0.61); 3.1154 (0.62); 3.1015 (2.12); 3.0973 (1.75); 3.0833 (3.21); 3.0693 (1.84); 3.0652 (2.23); 3.0513 (0.68); 3.0472 (0.66); 2.8570 (0.74); 2.8266 (1.35); 2.7988 (0.73); 2.6764 (0.53); 2.6718 (0.75); 2.6674 (0.55); 2.5420 (0.41); 2.5252 (1.25); 2.5205 (1.94); 2.5117 (39.18); 2.5073 (84.33); 2.5028 (113.58); 2.4982 (81.82); 2.4938 (39.24); 2.3341 (0.56); 2.3295 (0.77); 2.3251 (0.57); 2.1219 (0.91); 2.0885 (2.03); 2.0768 (16.00); 2.0638 (0.88); 2.0552 (1.08); 1.8289 (0.96); 1.8006 (0.85); 1.7756 (0.78); 1.5960 (0.40); 1.5747 (0.82); 1.5652 (0.93); 1.5440 (0.87); 1.5346 (0.83); 1.5136 (0.35); 1.1189 (0.97); 1.1013 (0.77); 1.0818 (6.68); 1.0638 (13.43); 1.0458 (6.13); 0.0080 (0.66); -0.0002 (24.03); -0.0084 (0.86

Pr. I-137, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.7774 (1.07); 8.0903 (1.27); 8.0800 (1.08); 8.0664 (1.48); 8.0182 (0.43); 7.9865 (2.48); 7.9781 (2.01); 7.9730 (2.12); 7.9633 (11.40); 7.9546 (2.24); 7.9481 (1.02); 7.6939 (2.12); 7.6914 (2.21); 7.6761 (2.60); 7.6736 (2.50); 7.6501 (0.39); 7.6467 (0.41); 7.6298 (0.38); 7.6257 (0.34); 7.6096 (0.38); 7.5901 (0.95); 7.5785 (2.91); 7.5744 (3.10); 7.5647 (3.51); 7.5547 (2.75); 7.5513 (2.34); 7.5394 (0.79); 7.5342 (0.48); 7.5295 (0.63); 7.5090 (2.74); 7.4910 (2.61); 7.4884 (2.63); 7.4704 (1.91); 7.4058 (1.59); 7.3860 (2.92); 7.3663 (2.08); 7.3057 (1.71); 7.1924 (1.88); 7.1872 (2.64); 7.1829 (2.32); 7.1724 (4.02); 71587 (2.03); 7.1196 (1.69); 7.1149 (1.41); 7.0992 (1.46); 7.0944 (1.29); 7.0560 (2.00); 7.0390 (3.38); 7.0227 (4.44); 6.9009 (3.87); 6.8868 (2.27); 5.7755 (1.14); 5.7549 (1.39); 5.7484 (1.38); 5.7278 (1.18); 5.4530 (0.49); 5.4463 (0.68); 5.4384 (0.76); 5.4234 (0.41); 5.4039 (2.61); 5.3657 (2.77); 5.3236 (0.73); 5.2A410 (9.84); 4.4708 (0.87); 4.4559 (0.88); 4.3521 (0.84); 4.3204 (0.88); 4.0575 (1.22); 4.0397 (3.65); 4.0219 (3.73); 4.0041 (1.38); 3.9731 (0.83); 3.9387 (0.88); 3.9152 (1.28); 3.8877 (1.42); 3.8721 (1.60); 3.8448 (1.91); 3.4127 (1.61); 3.3921 (1.92); 3.93697 (2.17); 3.3594 (1.68); 3.3493 (2.67); 3.3127 (459.35); 3.2609 (1.84); 3.2309 (0.98); 2.8633 (0.65); 2.8506 (0.48); 2.8349 (1.07); 2.8049 (0.62); 2.7359 (0.36); 2.6703 (0.42); 2.5403 (0.47); 2.5233 (1.24); 2.5101 (21.45); 2.5057 (40.97); 2.5012 (54.35); 2.4968 (38.02); 2.4924 (18.62); 2.3280 (0.43); 2.3235 (0.32); 2.1114 (0.87); 2.0769 (1.44); 2.0701 (1.49); 2.0425 (0.88); 1.9874 (16.00); 1.8186 (0.43); 1.7983 (0.66); 1.7901 (0.74); 1.7678 (0.63); 1.7601 (0.62); 1.5874 (0.46); 1.5665 (0.72); 1.5577 (0.79); 1.5368 (0.67); 1.5286 (0.65); 1.4100 (3.48); 1.3976 4.79); 1.2353 (0.65); 1.1931 (4.50); 1.1753 (8.84); 1.1575 (4.41); -0.0002 (5.11

Pr. I-138, Solvent: СсОоЗзСсМ, spectrometer: 399.95 MHz 7.9516 (9.69); 7.8395 (2.10); 7.8358 (1.71); 7.8216 (2.76); 7.8169 (2.36); 7.6275 (1.46); 7.6229 (1.77); 7.6050 (2.67); 7.5680 (0.92); 7.5638 (1.14); 7.5496 (2.70); 7.5453 (2.60); 7.5329 (3.43); 7.5280 (3.18); 7.5152 (2.37); 7.5109 (2.01); 7.4966 (0.76); 7.4925 (0.61); 7.0914 (10.75); 7.0428 (2.18); 6.9263 (2.32); 6.9077 (4.46); 6.8344 (3.64); 6.7895 (4.73); 6.7727 (2.25); 6.6527 (2.38); 5.2913 (0.80); 5.2488 (4.37); 5.2208 (4.34); 5.1784 (0.82); 4.7645 (16.00); 4.6931 (0.54); 4.5064 (0.95); 4.4725 (1.00); 4.4138 (0.66); 4.4077 (0.67); 4.2458 (11.95); 4.2398 (12.07); 4.1884 (0.34); 4.1823 (0.33); 4.0679 (0.60); 4.0501 (0.62); 3.9507 (0.89); 3.9146 (0.99); 3.4455 (0.41); 3.4359 (0.86); 3.4262 (0.51); 3.4170 (0.96); 3.4073 (1.86); 3.3976 (1.00); 3.3884 (0.57); 3.3788 (0.97); 3.3691 (0.53); 3.3590 (0.75); 3.3522 (0.82); 3.3229 (1.34); 3.2943 (0.76); 3.2871 (0.69); 2.9355 (0.65); 2.9286 (0.73); 2.8980 (1.22); 2.8719 (0.73); 2.8654 (0.69); 2.7560 (2.20); 2.7501 (4.27); 2.7441 (2.19); 2.2649 (0.78); 2.2253 (1.20); 22183 (1.17); 2.1798 (0.94); 2.1415 (27.90); 2.1377 (24.49); 2.1197 (0.61); 2.1131 (0.61); 2.1069 (0.66); 2.1008 (0.48); 1.9716 (2.43); 1.9638 (2.83); 1.9577 (3.64); 1.9519 (25.59); 1.9457 (47.80); 1.9396 (65.88); 1.9334 (45.65); 1.9272 (24.43); 1.8963 (1.18); 1.8868 (1.10); 1.8663 (0.58); 1.8560 (0.53); 1.6067 (0.56); 1.7959 (0.58); 1.7 745 (1.18); 1.7677 (1.26); 1.7557 (0.43); 1.7446 (0.94); 1.7339 (0.91); 1.7149 (0.47); 1.7034 (0.43); 1.4367 (2.06); 1.2763 (0.33); 1.2214 (0.71); 1.2036 (1.33); 1.1858 (0.68); -0.0002 (10.88); -0.0085 (0.44

Pr. I-139, Solvent: СсОоЗзСсМ, spectrometer: 399.95 MHz 7.9422 (11.38); 7.9325 (0.34); 7.8336 (2.30); 7.8301 (2.02); 7.8152 (2.86); 7.8111 (2.51); 7.6398 (1.70); 7.6363 (1.92); 7.6206 (2.52); 7.6181 (2.75); 7.5601 (1.07); 7.5562 (1.24); 7.5416 (2.84); 7.5376 (2.70); 7.5234 (2.31); 7.5185 (3.61); 7.5136 (2.31); 7.4994 (2.63); 7.4953 (2.37); 7.4807 (0.99); 7.4769 (0.82); 7.0735 (12.12); 7.0413 (2.30); 7.0240 (0.35); 6.9254 (2.51); 6.9062 (4.69); 6.8340 (3.89); 6.7886 (5.05); 6.7712 (2.37); 6.6518 (2.56); 6.0273 (0.58); 6.0136 (1.20); 6.0006 (0.99); 5.9874 (1.40); 5.9842 (0.82); 5.9736 (0.84); 5.9704 (1.47); 5.9575 (1.14); 5.9442 (1.47); 5.9306 (0.76); 5.3334 (0.93); 5.3291 (2.31); 5.3247 (2.37); 5.3204 (0.99); 5.2900 (1.56); 5.2860 (2.70); 5.2815 (2.28); 52773 (0.97); 5.2461 (4.73); 5.2199 (4.67); 5.1923 (1.09); 5.1890 (2.22); 5.1844 (2.19); 5.1809 (1.47); 5.1661 (1.12); 5.1628 (2.07); 5.1583 (1.99); 5.1550 (1.04); 4.6874 (16.00); 4.6497 (0.44); 4.5028 (1.00); 4.4683 (1.04); 4.0893 (3.70); 4.0857 (6.04); 4.0821 (3.77); 4.0757 (3.81); 4.0720 (5.96); 4.0684 (3.56); 3.9475 (0.98); 3.9123 (1.09); 3.4421 (0.44); 3.4323 (0.92); 3.4225 (0.55); 3.4135 (1.02); 3.4038 (1.95); 3.3941 (1.05); 3.3850 (0.62); 3.3753 (1.05); 3.3655 (0.61); 3.357 7 (0.82); 3.3507 (0.88); 3.3216 (1.43); 3.2928 (0.83); 3.2858 (0.75); 2.9371 (0.73); 2.9303 (0.78); 2.9047 (1.25); 2.8996 (1.28); 2.8735 (0.78); 2.8668 (0.72); 2.2600 (0.85); 2.2220 (1.932); 22156 (1.27); 2.1778 (1.06); 2.1389 (22.94); 2.1195 (0.40); 21132 (0.42); 2.1069 (0.49); 2.1009 (0.35); 1.9639 (2.08); 1.9576 (2.78); 1.9519 (18.28); 1.9458 (34.33); 1.9396 (46.88); 1.9334 (32.22); 1.9272 (17.28); 1.9171 (1.44); 1.8943 (1.01); 1.8847 (0.92); 1.8650 (0.47); 1.8543 (0.41); 1.8069 (0.49); 1.7963 (0.54); 1.7746 (1.04); 1.7678 (1.20); 1.7555 (0.36); 1.7452 (0.92); 1.7351 (0.87); 1.7153 (0.44); 1.7048 (0.39); 1.3714 (0.63); 1.3402 (0.77); 1.2847 (1.04); 1.2761 (0.97); 1.2688 (0.83); -0.0002 (7.70

Pr. I-140, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0244 (9.48); 7.4168 (0.68); 7.125 (0.95); 7.3926 (1.68); 7.3778 (2.74); 7.3736 (2.91); 7.3589 (2.21); 7.2155 (2.56); 7,1964 (2,11); 7.1139 (1.37); 7.0959 (2.41); 7.0772 (1.11); 6.4964 (4.41); 5.9017 (1.19); 5.8839 (1.35); 5.8741 (1.33); 5.8558 (1.27); 5.7550 (13.33); 5.3468 (0.84); 5.3041 (2.59); 5.2536 (2.57); 5.2404 (12.85); 5.2114 (0.83); 4.3812 (0.72); 4.3472 (0.71); 3.9833 (0.67); 3.9492 (0.71); 3.9179 (1.32); 3.8899 (1.51); 3.8748 (1.73); 3.8471 (1.43); 3.4003 (0.59); 3.3905 (0.45); 3.3799 (0.71); 3.3715 (1.33); 3.3621 (1.15); 3.3384 (219.17); 3.3318 (186.18); 3.3283 (225.94); 3.3255 (247.43); 3.3042 (2.68); 3.2908 (2.47); 3.2728 (1.95); 3.2588 (1.05); 3.2477 (1.68); 3.2298 (1.96); 2.8585 (0.51); 2.8333 (0.85); 2.8016 (0.54); 2.6753 (0.67); 2.6705 (0.98); 2.6664 (0.71); 2.5409 (0.53); 2.5241 (1.66); 2.5194 (2.38); 2.5102 (56.20); 2.5060 (108.60); 2.5017 (150.67); 2.4975 (103.44); 2.4932 (50.87); 2.3378 (0.34); 2.3330 (0.75); 2.3284 (0.97); 2.3240 (0.67); 2.2055 (16.00); 2.1259 (0.61); 2.0973 (1.29); 2.0733 (2.06); 1.8149 (0.55); 1.8081 (0.58); 1.7858 (0.56); 1.7759 (0.51); 1.5753 (0.53); 1.5661 (0.57); 1.5437 (0.56); 1.5344 (0.51); 1.2351 (0.47); 0.0080 (1.39); -0.0002 (49.76); -0.0086 (1.41)

Pr. I-141, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0252 (9.43); 7.3115 (1.56); 7.1921 (1.51); 7.1781 (4.67); 7.1713 (7.77); 7.1084 (3.35); 7.0880 (2.14); 7.0451 (1.78); 7.0328 (4.04); 6.9081 (3.50); 6.8970 (2.00); 5.8669 (1.37); 5.8485 (1.59); 5.8391 (1.53); 5.8206 (1.38); 5.7592 (4.48); 5.4595 (0.88); 5.4169 (2.82); 5.3737 (2.77); 5.3312 (0.87); 5.1947 (13.81); 4.3629 (0.83); 4.3295 (0.85); 4.0374 (0.57); 4.0196 (0.60); 3.9790 (0.76); 3.9447 (0.84); 3.9057 (1.38); 3.8776 (1.62); 3.8626 (1.82); 3.8346 (1.49); 3.4066 (0.59); 3.3972 (0.44); 3.3873 (0.69); 3.3777 (1.26); 3.3683 (0.75); 3.3588 (0.57); 3.3487 (1.00); 3.3285 (95.13); 3.2885 (0.69); 32755 (1.87); 3.2571 (2.65); 3.2323 (2.02); 3.2142 (1.62); 2.8579 (0.59); 2.8273 (1.03); 2.7995 (0.58); 2.6754 (0.42); 2.6708 (0.59); 2.6662 (0.43); 2.5408 (0.40); 2.5241 (2.12); 2.5107 (32.27); 2.5063 (65.07); 2.5017 (86.42); 2.4971 (63.31); 2.4927 (30.85); 2.3328 (0.48); 2.3286 (0.69); 2.3240 (0.47); 22611 (16.00); 2.1256 (0.71); 2.0911 (1.51); 2.0569 (0.83); 1.9892 (2.52); 1.8118 (0.66); 1.8044 (0.73); 1.7815 (0.65); 1.7 744 (0.61); 1.5749 (0.65); 1.5666 (0.71); 1.5454 (0.66); 1.5359 (0.64); 1.1921 (0.70); 1.1743 (1.39); 1.1565 (0.68); 0.0080 (0.55); -0.0002 (15.40); -0.0084 (0.58

Pr. I-142, Solvent: dmeoo-ab, spectrometer: 399.95 MHz 8.0161 (7.00); 7.2429 (2.73); 7.2235 (3.08); 7.0394 (3.68); 6.9128 (1.98); 6.8937 (1.78); 6.4987 (4.18); 5.8531 (1.14); 5.8346 (1.34); 5.8254 (1.31); 5.8069 (1.18); 5.7588 (4.38); 5.3511 (0.96); 5.3085 (2.73); 52581 (2.66); 5.2116 (11.88); 4.3818 (0.80); 4.3487 (0.83); 3.9820 (0.75); 3.9497 (0.81); 3.8747 (1.17); 3.8469 (1.34); 3.8318 (1.54); 3.8041 (1.28); 3.3996 (0.56); 3.3896 (0.44); 3.3798 (0.76); 3.3708 (1.27); 3.3613 (1.06); 3.3287 (106.18); 3.2877 (0.74); 3.2725 (1.68); 3.2544 (2.27); 3.2297 (1.86); 3.2113 (1.37); 2.8575 (0.55); 2.8305 (1.00); 2.7997 (0.57); 2.6748 (0.36); 2.6706 (0.48); 2.6664 (0.37); 2.5058 (56.62); 2.5015 (73.74); 2.4972 (55.51); 2.3286 (14.03); 2.2044 (16.00); 2.1220 (0.73); 2.0911 (1.54); 2.0629 (0.86); 1.9890 (1.23); 1.8161 (0.63); 1.8074 (0.69); 1.7852 (0.63); 1.7775 (0.59); 1.5724 (0.64); 1.5621 (0.70); 1.5415 (0.65); 1.5321 (0.63); 1.1920 (0.32); 1.1743 (0.65); 1.1564 (0.92); - 0.0002 (11.15); -0.0083 (0.62

Pr. I-143, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0264 (8.21); 7.4170 (0.74); 7.4129 (0.90); 7.3939 (1.67); 7.3780 (2.59); 7.3740 (2.71); 7.3588 (2.04); 7.2170 (2.57); 7.2076 (1.55); 7,1968 (2,11); 7.1138 (1.37); 7.0951 (2.34); 7.0732 (3.58); 6.9384 (1.50); 6.3843 (3.27); 5.9020 (1.14); 5.8841 (1.31); 5.8743 (1.29); 5.8562 (1.16); 5.7590 (11.78); 5.2448 (12.75); 5.1995 (2.65); 5.1609 (2.59); 5.1187 (0.68); 4.3628 (0.69); 4.3291 (0.72); 4.0375 (0.55); 4.0197 (0.58); 4.0017 (0.50); 3.9914 (0.64); 3.9566 (0.71); 3.9188 (1.22); 3.8909 (1.41); 3.8758 (1.56); 3.8480 (1.91); 3.3934 (0.49); 3.3838 (0.95); 3.3737 (0.62); 3.3643 (1.11); 3.3551 (0.68); 3.3295 (57.52); 3.2902 (1.51); 3.2721 (1.80); 3.2472 (1.56); 3.2295 (1.93); 3.2056 (0.49); 2.8329 (0.48); 2.8036 (0.87); 2.7752 (0.48); 2.6710 (0.33); 2.5241 (1.25); 2.5108 (19.67); 2.5065 (38.51); 2.5020 (50.06); 2.4974 (36.40); 2.4931 (17.90); 2.3286 (0.95); 2.1608 (16.00); 2.1069 (0.65); 2.0750 (1.36); 2.0468 (0.74); 1.9893 (2.44); 1.7743 (0.55); 1.7672 (0.60); 1.7447 (0.55); 1.7367 (0.51); 1.5600 (0.55); 1.5506 (0.60); 1.5295 (0.56); 1.5205 (0.54); 1.1922 (0.65); 1.1744 (1.27); 1.1566 (0.62); -0.0002 (1.30

Pr. I-144, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0171 (11.14); 7.3119 (1.66); 7.2446 (3.33); 7.2252 (3.77); 7.1787 (3.96); 7.1687 (1.93); 7.0414 (4.37); 7.0328 (4.93); 6.9110 (4.29); 6.8968 (3.85); 5.8551 (1.32); 5.8367 (1.53); 5.8275 (1.50); 5.8090 (1.95); 5.7588 (13.01); 5.4593 (0.90); 5.4168 (2.93); 5.3743 (2.87); 5.3317 (0.89); 5.2129 (14.97); 4.3620 (0.83); 4.3280 (0.88); 4.0555 (0.55); 4.0377 (1.70); 4.0199 (1.72); 4.0021 (0.64); 3.9792 (0.78); 3.9448 (0.85); 3.8760 (1.46); 3.8482 (1.76); 3.8331 (1.96); 3.8054 (1.58); 3.4047 (0.59); 3.3953 (0.41); 3.3854 (0.72); 3.3761 (1.25); 3.93667 (0.74); 3.3565 (0.54); 3.3468 (0.92); 3.3297 (52.57); 3.2889 (0.67); 3.27A41 (1.98); 3.2557 (2.71); 3.2312 (2.19); 3.2129 (1.70); 2.8579 (0.59); 2.8273 (1.05); 2.8011 (0.59); 2.6711 (0.35); 2.5245 (1.23); 2.5197 (1.95); 2.5112 (19.18); 2.5067 (38.56); 2.5021 (50.85); 2.4975 (36.83); 2.4930 (17.86); 2.3298 (16.00); 2.1247 (0.72); 2.0917 (1.52); 2.0756 (0.72); 2.0577 (0.84); 1.9894 (7.55); 1.8347 (0.33); 1.8134 (0.67); 1.8046 (0.73); 1.7826 (0.68); 1.7742 (0.63); 1.5964 (0.33); 1.5755 (0.66); 1.5663 (0.75); 1.5451 (0.69); 1.5358 (0.66); 1.1923 (2.05); 1.1745 (4.09); 1.1567 2.01); -0.0002 (1.74

Pr. I-145, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0777 (5.90); 8.0540 (0.37); 7.6539 (1.28); 7.6486 (1.39); 7.6351 (1.58); 7.6299 (1.66); 7.4775 (0.55); 7.4722 (0.82); 7.4576 (2.38); 7.4524 (2.05); 7.4458 (2.38); 7.4267 (2.21); 7.4072 (0.77); 7.3123 (0.99); 7.1790 (2.27); 7.1682 (1.18); 7.0459 (1.14); 7.0322 (2.76); 6.9077 (2.46); 6.8965 (1.37); 6.0318 (0.90); 6.0130 (1.07); 6.0040 (1.03); 5.9851 (0.93); 5.7583 (7.50); 5.4617 (0.57); 5.4192 (1.78); 5.3754 (1.91); 5.3326 (0.60); 4.3667 (0.55); 4.3343 (0.59); 4.0554 (0.45); 4.0376 (1.35); 4.0197 (1.43); 4.0105 (0.87); 4.0019 (0.59); 3.9825 (1.48); 3.9668 (1.932); 3.9390 (1.91); 3.7244 (16.00); 3.4093 (1.23); 3.3901 (1.50); 3.3778 (0.55); 3.3657 (1.22); 3.3588 (0.62); 3.3469 (1.32); 3.3292 (50.69); 3.2900 (0.46); 3.2599 (0.78); 3.2305 (0.42); 2.8584 (0.40); 2.68279 (0.72); 2.8003 (0.41); 2.6711 (0.38); 2.5244 (1.36); 2.5110 (22.32); 2.5066 (44.26); 2.5021 (57.93); 2.4976 (42.65); 24932 (21.32); 2.3289 (0.46); 2.1311 (0.51); 2.0961 (1.07); 2.0613 (0.59); 1.9892 (5.90); 1.8191 (0.45); 1.8112 (0.49); 1.7887 (0.45); 1.7806 (0.44); 1.57 77 (0.46); 1.5693 (0.50); 1.5479 (0.48); 1.5387 (0.45); 1.1925 (1.60); 1.1747 (3.22); 1.1569 1.56); 0.0080 (0.61); -0.0002 (16.07); -0.0084 (0.70

Pr. I-146, Solvent: dmeoo-abvb, spectrometer: 399.95 MHz 8.0535 (9.44); 7.5691 (2.16); 7.5651 (2.39); 7.5493 (2.63); 7.5453 (2.70); 7.3988 (1.68); 7.3949 (1.79); 7.3792 (2.69); 7.3754 (2.46); 7.3113 (3.50); 7.2913 (4.08); 7.2717 (1.69); 7.1802 (3.63); 7.1694 (1.79); 7.0470 (1.77); 7.0334 (4.12); 6.9090 (3.72); 6.8976 (2.09); 6.0150 (1.39); 5.9960 (1.63); 5.9871 (1.59); 5.9679 (1.41); 5.7588 (3.21); 5.4617 (0.89); 5.4191 (2.89); 5.3770 (2.91); 5.3344 (0.90); 5.1522 (1.58); 5.1121 (7.56); 5.0947 (7.50); 5.0547 (1.65); 4.3647 (0.87); 4.3314 (0.91); 4.0555 (1.20); 4.037 7 (3.68); 4.0199 (3.75); 4.0020 (1.53); 3.9956 (1.72); 3.9842 (0.88); 3.9676 (1.88); 3.9523 (2.59); 3.9243 (1.54); 3.4244 (0.34); 3.4096 (1.98); 3.3903 (2.43); 3.3783 (0.83); 3.3664 (1.89); 3.3587 (0.91); 3.3473 (2.05); 3.3306 (50.65); 3.2947 (0.72); 3.2641 (1.15); 3.2358 (0.62); 2.8644 (0.61); 2.8339 (1.08); 2.8071 (0.61); 2.5109 (18.17); 2.5067 (35.81); 2.5022 (46.86); 2.4977 (34.53); 2.4934 (17.30); 2.3289 (0.32); 2.1338 (0.76); 2.0992 (1.60); 2.0651 (0.89); 1.9894 (16.00); 1.8423 (0.34); 1.8211 (0.70); 1.8125 (0.76); 1.7907 (0.69); 1.7820 (0.65); 1.6049 (0.33); 1.5838 (0.70); 1.5746 (0.77); 1.5532 (0.71); 1.5446 0.68); 1.1925 (4.34); 1.1747 (8.57); 1.1569 (4.25); 0.0079 (0.50); -0.0002 (12.85); -0.0085 (0.57

The intensity of the clear signals is correlated with the height of the signals in the printed example NMR spectrum in cm, it shows the true ratio of the signal intensities. In the case of broad signals, multiple peaks or the midpoint of the signal and their relative intensity compared to the most intense signal in the spectrum may be displayed.

The H-NMR peak list is similar to standard H-NMR data and thus usually contains all the peaks given in the classical NMR interpretation.

In addition, they can, like standard H-NMR, show solvent signals, signals of stereoisomers of the target compounds, which are also the object of the invention, and/or impurity peaks.

When the signals of a compound in the delta range of solvents and/or water are indicated in our "H-NMR" peak lists, the usual solvent peaks are given, for example, the DMSO peaks in DMSO-v and the water peak, which usually have a high intensity on average.

Stereoisomeric peaks of the target compounds and/or impurity peaks are usually of low intensity on average compared to the peaks of the target compounds (eg purity 290 95).

Such stereoisomers and/or impurities may be typical of the respective preparation method. Thus, their peaks can help in revealing the reproducibility of our preparation method based on the "fingerprints" of byproducts.

An expert who counts the peaks of target compounds by known methods (MezigeS, ASO-

Bithyiop, as well as with the help of empirically estimated expected values) can highlight the peaks of the target compounds if necessary, and additional intensity filters can optionally be used. Such a selection would be similar to the corresponding collection of peaks in the standard interpretation of "H-NMR.

The table shows all the NMR data, both for the final compounds and for the intermediate compounds.

Application examples

Example A

Rpuiorpipoga- research (tomatoes) / protective action

Solvent: 49 wt. parts of M,M-dimethylformamide

Emulsifier: 1 wt. alkylaryl polyglycol ether moiety

To obtain the required composition of active substances, 1 mass part of the active substance is mixed with the specified amount of solvent and emulsifier, and the concentrate is diluted to the required concentration with water.

To study the protective action of young tomato plants, they are sprayed with a composition of active substances in the prescribed amount. 1 day after the treatment of the plants After the drying of the spraying solution, the plants are inoculated with a spore suspension of RPuforpiivpoga iptekhiapv5, and then the plants are left for 24 hours at a relative humidity of approx. 100 95 and a temperature of 22 "C. Then the plants are placed in climate chambers at a relative humidity of approx. 96 95 and a temperature of 20 "C.

After 7 days after infection, the assessment is carried out. At the same time, 0 95 means a degree of action that corresponds to the control group, while a degree of action of 100 95 means that no damage is observed.

In this study, the following compounds according to the present invention, at an active substance concentration of 100 million parts, show a degree of effectiveness of 70 95 or higher:

OBO OKU KE E OO KO OH Z ! OK и и ХУ KЖО Z MM Z

Se 00 a loyu ho a MY va. ши AN -- 86400. 400 ОЗ 85 шых ШВИ З 100 вв НО M 60100 Village Svv ! SB VV sends 9 38 0100. 8 Gv8o ! St

In 04000000140 04000000 811 00000007 ! V. bo -50O .Yav 100 shk Shy Shy Sv ve

M 2100 ia svia 08000020 89

KM 85 Pi» AND LY 8575 AYU

I am OO VVA 8600075 18987

MV 100. Sha 8385 184100 tlo svva shcha 100 12689 220400. g nshi vav 19500081 100,

Fa 10010000 1650041 000400 01001000 times 0100.

FU 100. n: we are shn sy ie: nik vav 40000060 vya 00000003 80000000 3683 ee 400. )0061 89 I 87 137100

E8O 100 68 Vo aut 86 KESNSHKNY

SHE MO. shah IM lov 100. Saotva 83010018 000 10001МО 00,

Example B

Riaztoraga - research (grape) / protective action

Solvent: 24.5 wt. parts of acetone 24.5 wt. parts of dimethylacetamide

Emulsifier: 1 wt. alkylaryl polyglycol ether moiety

To obtain the required composition of active substances, 1 mass part of the active substance is mixed with a certain amount of solvent and emulsifier, and the concentrate is diluted to the required concentration with water.

To study the protective effect, young plants are sprayed with a composition of active substances in the prescribed amount. After drying of the spraying solution, the plants are inoculated with an aqueous suspension of spores of Riaztoraga mysoia and then left for 1 day in an incubation cabin at a temperature of approximately 20 "С and at a relative humidity of 100,905.

Then, the plants are placed for 4 days in a greenhouse at a temperature of approximately 21 "С and at a relative humidity of approximately 90 95. Then the plants are moistened and placed for 1 day in the incubation cabin.

After 6 days after infection, the assessment is carried out. At the same time, 0 95 means a degree of action that corresponds to the control group, while a degree of action of 100 95 means that no damage is observed.

In this study, the following compounds according to the present invention, with an active substance concentration of 10 ppm. exhibit a degree of efficiency of 70 95 or higher:

shi 34 87 "KIV. 100. | 788, 412100 5 loyu Sat 93 MV t00

BV V NE i Na SE NIM POETY - T 190. 3895 SBU ly nin lish o. BV VV vanna as a village V vav 12289

Б В -jav v VZ aa Z veli AT VO SEVya 100.) slya 100. vo va 86 | 850100 La5 100 little holy 100.) like our nyshshk

ZHE 00 SBU OLOKH 100 of you insny

Svv at 06 OZ 100 SIV 106

Tay Sv 100 ov 93 M v obvoila lo | La 100. av vv.

EE I 06 I lo. 3888 (321 85 Set lov la 100

Example C

Regopozroga - research (seed material of oilseed rape) / seed treatment

Research is carried out in greenhouse conditions.

The seed material of oilseed rape, treated with an active compound or a combination of active compounds, according to the present invention, dissolved in M-methyl-2-pyrrolidone and diluted with water to obtain the required dose, was sown in vessels measuring 6 x cm. The vessels contained 4 cm of a mixture of steamed field soil. and sand Plants were grown at a temperature of 10 °C.

14-day-old plants were inoculated with an aqueous suspension of spores of Regopozrog bgazzisae. Vessels containing plants were incubated in a greenhouse at a temperature of 15 "С and at a relative humidity of 100 95 for 7 days.

Evaluation of the study included the determination of the area of leaf infection per plant. At the same time, 0 95 means the degree of action that corresponds to the untreated control group, while the degree of action of 100 95 means that no diseases are observed.

In this study, the following compounds showed an efficiency of 70 95 or higher at a dosage of 50 g/centenary of the active compound according to the invention.

AND

M

4 that 650 95 8 -KVE AYU. - 85 1 80 ha | 100

Claims (1)

THE FORMULA OF THE INVENTION The compound of the formula E E (c) - Shk Z E -ldj M X M M her E i M (c) SI (c) o, 57 i (c)