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TR200001530T2 - Gastrik asit salgılamasının önlenmesi için heterosiklik bileşimler - Google Patents

Gastrik asit salgılamasının önlenmesi için heterosiklik bileşimler

Info

Publication number
TR200001530T2
TR200001530T2 TR2000/01530T TR200001530T TR200001530T2 TR 200001530 T2 TR200001530 T2 TR 200001530T2 TR 2000/01530 T TR2000/01530 T TR 2000/01530T TR 200001530 T TR200001530 T TR 200001530T TR 200001530 T2 TR200001530 T2 TR 200001530T2
Authority
TR
Turkey
Prior art keywords
gastric acid
acid secretion
prevent gastric
heterocyclic compositions
heterocyclic
Prior art date
Application number
TR2000/01530T
Other languages
English (en)
Inventor
Amin Kostrat
Dahlstr�m Mikael
Nordberg Peter
Starke Ingemar
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of TR200001530T2 publication Critical patent/TR200001530T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Mevcut bulus, egzojen ve endojen olarak stimüle edilmis gastrik asit salgilanmasini önleyen ve böylece gastrointestinal iltihapli hastaliklarin önlenmesi ve tedavisinde kullanilabilen formül (I)'in heteosiklik bilesimleri ile ilgilidir, burada fenil parçaci 2- e 6- pozisyonunda düsük alkil ile ikame edilir.
TR2000/01530T 1997-11-28 1998-11-18 Gastrik asit salgılamasının önlenmesi için heterosiklik bileşimler TR200001530T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9704404A SE9704404D0 (sv) 1997-11-28 1997-11-28 New compounds

Publications (1)

Publication Number Publication Date
TR200001530T2 true TR200001530T2 (tr) 2000-11-21

Family

ID=20409181

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/01530T TR200001530T2 (tr) 1997-11-28 1998-11-18 Gastrik asit salgılamasının önlenmesi için heterosiklik bileşimler

Country Status (33)

Country Link
US (1) US6518270B1 (tr)
EP (1) EP1042324B1 (tr)
JP (1) JP2001525322A (tr)
KR (1) KR20010032559A (tr)
CN (1) CN1142933C (tr)
AR (1) AR016972A1 (tr)
AT (1) ATE233263T1 (tr)
AU (1) AU752187C (tr)
BR (1) BR9814755A (tr)
CA (1) CA2311798A1 (tr)
CZ (1) CZ292349B6 (tr)
DE (1) DE69811735T2 (tr)
DK (1) DK1042324T3 (tr)
EE (1) EE04060B1 (tr)
ES (1) ES2191356T3 (tr)
HK (1) HK1030216A1 (tr)
HU (1) HUP0100601A3 (tr)
ID (1) ID24730A (tr)
IL (1) IL136145A0 (tr)
IS (1) IS5486A (tr)
MY (1) MY121032A (tr)
NO (1) NO315704B1 (tr)
NZ (1) NZ504355A (tr)
PL (1) PL340920A1 (tr)
PT (1) PT1042324E (tr)
RU (1) RU2241000C2 (tr)
SE (1) SE9704404D0 (tr)
SK (1) SK283904B6 (tr)
TR (1) TR200001530T2 (tr)
TW (1) TW515798B (tr)
UA (1) UA70932C2 (tr)
WO (1) WO1999028322A1 (tr)
ZA (1) ZA9810468B (tr)

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WO2004029058A1 (ja) * 2002-09-25 2004-04-08 Sankyo Company, Limited 血中ガストリン濃度上昇の抑制のための医薬組成物
WO2004029057A1 (ja) * 2002-09-25 2004-04-08 Sankyo Company, Limited 内臓痛の治療または予防のための医薬組成物
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WO2004072081A1 (en) 2003-02-10 2004-08-26 Cellular Genomics, Inc. Certain 8-heteroaryl-6-phenyl-imidazo[1,2-a]pyrazines as modulators of kinase activity
AR043002A1 (es) * 2003-02-18 2005-07-13 Altana Pharma Ag Imidazopirazinas 6-substituidos
JP4880448B2 (ja) * 2003-03-17 2012-02-22 アフィナム ファーマシューティカルズ，インコーポレーテッド 複数の抗生物質を含む組成物、及びそれを用いる方法
US7405295B2 (en) 2003-06-04 2008-07-29 Cgi Pharmaceuticals, Inc. Certain imidazo[1,2-a]pyrazin-8-ylamines and method of inhibition of Bruton's tyrosine kinase by such compounds
US7393848B2 (en) 2003-06-30 2008-07-01 Cgi Pharmaceuticals, Inc. Certain heterocyclic substituted imidazo[1,2-A]pyrazin-8-ylamines and methods of inhibition of Bruton's tyrosine kinase by such compounds
WO2005019220A2 (en) 2003-08-11 2005-03-03 Cellular Genomics Inc. Substituted imidazo[1,2-a]pyrazines as modulators of kinase activity
US20080280944A1 (en) 2003-11-03 2008-11-13 Paula Fernstrom Imidazo[1,2-A]Pyridine Derivatives For The Treatment Of Silent Gastro-Esophageal Reflux
EP2848614A3 (en) * 2004-06-04 2015-07-29 Debiopharm International SA Acrylamide derivatives as antibiotic agents
KR102152809B1 (ko) * 2004-07-28 2020-09-07 다케다 야쿠힌 고교 가부시키가이샤 피롤로〔2,3-ｃ〕피리딘 화합물, 그 제조 방법 및 용도
JP2008508347A (ja) * 2004-08-02 2008-03-21 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング ５置換された１Ｈ−ピロロ［３，２−ｂ］ピリジン
CA2578880C (en) 2004-09-03 2013-01-29 Yuhan Corporation Pyrrolo[3,2-c]pyridine derivatives and processes for the preparation thereof
WO2006038773A1 (en) * 2004-09-03 2006-04-13 Yuhan Corporation Pyrrolo[3,2-b]pyridine derivatives and processes for the preparation thereof
WO2006025715A1 (en) * 2004-09-03 2006-03-09 Yuhan Corporation Pyrrolo[3,2-c]pyridine derivatives and processes for the preparation thereof
AU2005280740B2 (en) 2004-09-03 2011-04-28 Yuhan Corporation Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof
US7777040B2 (en) 2005-05-03 2010-08-17 Cgi Pharmaceuticals, Inc. Certain substituted ureas, as modulators of kinase activity
CA2620223A1 (en) 2005-09-02 2007-03-08 Abbott Laboratories Novel imidazo based heterocycles
WO2007067416A2 (en) * 2005-12-05 2007-06-14 Affinium Pharmaceuticals, Inc. Heterocyclylacrylamide compounds as fabi inhibitors and antibacterial agents
WO2007145921A1 (en) * 2006-06-06 2007-12-21 Schering Corporation Imidazopyrazines as protein kinase inhibitors
CA2658506C (en) 2006-07-20 2016-01-26 Affinium Pharmaceuticals, Inc. Acrylamide derivatives as fab 1 inhibitors
EP3255045A1 (en) 2007-02-16 2017-12-13 Debiopharm International SA Salts, prodrugs and polymorphs of fab i inhibitors
JP5496915B2 (ja) 2008-02-13 2014-05-21 シージーアイ ファーマシューティカルズ，インコーポレーテッド ６−アリール−イミダゾ［１，２−ａ］ピラジン誘導体、その製造方法、及びその使用方法
US8450321B2 (en) 2008-12-08 2013-05-28 Gilead Connecticut, Inc. 6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
US8440667B2 (en) 2008-12-08 2013-05-14 Gilead Connecticut, Inc. Imidazopyrazine Syk inhibitors
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BR112012022943A2 (pt) 2010-03-11 2018-06-05 Gilead Connecticut Inc inibidores de syk de imidazopiridnas
ME03392B (me) 2012-06-19 2020-01-20 Debiopharm Int Sa Prolek derivati (e)-n-meтil-n-( (з-метi lbenzofuran-2-il)meтil)-3-(7 -okso-5 ,6, 7,8-тетrанidr0-1,8-nafтiridin-3-il)akrilamida
PL3027171T3 (pl) 2013-07-30 2020-08-24 Gilead Connecticut, Inc. Formulacja inhibitorów syk
MX2016001304A (es) 2013-07-30 2016-04-07 Gilead Connecticut Inc Polimorfo de inhibidores de syk.
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TWI662037B (zh) 2013-12-23 2019-06-11 美商基利科學股份有限公司 脾酪胺酸激酶抑制劑
CN106687139A (zh) 2014-07-14 2017-05-17 吉利德科学公司 用于治疗癌症的组合
EA037121B1 (ru) 2016-02-26 2021-02-09 Дебиофарм Интернэшнл C.A. Лекарственное средство для лечения инфекций на фоне диабетической стопы
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AU2020225455A1 (en) 2019-02-22 2021-09-09 Kronos Bio, Inc. Solid forms of condensed pyrazines as Syk inhibitors

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EP0068378B1 (en) * 1981-06-26 1986-03-05 Schering Corporation Novel imidazo(1,2-a)pyridines and pyrazines, processes for their preparation and pharmaceutical compositions containing them
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SE9602286D0 (sv) 1996-06-10 1996-06-10 Astra Ab New compounds
SE9700661D0 (sv) 1997-02-25 1997-02-25 Astra Ab New compounds
SE9704404D0 (sv) 1997-11-28 1997-11-28 Astra Ab New compounds

Also Published As

Publication number Publication date
JP2001525322A (ja) 2001-12-11
DK1042324T3 (da) 2003-05-05
CZ20001947A3 (cs) 2000-11-15
HUP0100601A2 (hu) 2001-09-28
MY121032A (en) 2005-12-30
EE04060B1 (et) 2003-06-16
NO20002721L (no) 2000-07-28
KR20010032559A (ko) 2001-04-25
CN1142933C (zh) 2004-03-24
SE9704404D0 (sv) 1997-11-28
NO20002721D0 (no) 2000-05-26
NO315704B1 (no) 2003-10-13
US6518270B1 (en) 2003-02-11
RU2241000C2 (ru) 2004-11-27
HUP0100601A3 (en) 2002-10-28
IL136145A0 (en) 2001-05-20
NZ504355A (en) 2001-12-21
PL340920A1 (en) 2001-03-12
PT1042324E (pt) 2003-06-30
DE69811735D1 (de) 2003-04-03
AU1356599A (en) 1999-06-16
AU752187B2 (en) 2002-09-12
BR9814755A (pt) 2000-10-03
EP1042324B1 (en) 2003-02-26
TW515798B (en) 2003-01-01
EP1042324A1 (en) 2000-10-11
SK283904B6 (sk) 2004-04-06
CA2311798A1 (en) 1999-06-10
AU752187C (en) 2003-09-18
CN1284078A (zh) 2001-02-14
ES2191356T3 (es) 2003-09-01
ID24730A (id) 2000-08-03
SK6742000A3 (en) 2001-03-12
WO1999028322A1 (en) 1999-06-10
UA70932C2 (uk) 2004-11-15
DE69811735T2 (de) 2003-12-18
HK1030216A1 (en) 2001-04-27
AR016972A1 (es) 2001-08-01
CZ292349B6 (cs) 2003-09-17
ATE233263T1 (de) 2003-03-15
IS5486A (is) 2000-05-10
ZA9810468B (en) 1999-05-21
EE200000315A (et) 2001-10-15

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