TR199700020T1 - Selüler yapisma inhibitörü olarak (-)-(3R)-3-metil-4-£4-£4-(4-piridil) piperazin-1-il-|fenoksi|bütirik asit. - Google Patents

Selüler yapisma inhibitörü olarak (-)-(3R)-3-metil-4-£4-£4-(4-piridil) piperazin-1-il-|fenoksi|bütirik asit.

Info

Publication number: TR199700020T1
Authority: TR; Turkey
Prior art keywords: piperazin; phenoxy; pyridyl; methyl; butyric acid
Prior art date: 1995-06-01

Application number

TR97/00020T

Other languages

English (en)

Turkish (tr)

Inventor

Stuart Dennett Mills

Original Assignee

Zeneca Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-01

Filing date

1996-05-28

Publication date

1997-04-22

1995-06-01 Priority claimed from US08/457,538 external-priority patent/US5652242A/en

1995-09-07 Priority claimed from GBGB9518188.9A external-priority patent/GB9518188D0/en

1996-05-28 Application filed by Zeneca Ltd filed Critical Zeneca Ltd

1997-04-22 Publication of TR199700020T1 publication Critical patent/TR199700020T1/xx

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Hematology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

TR97/00020T 1995-06-01 1996-05-28 Selüler yapisma inhibitörü olarak (-)-(3R)-3-metil-4-£4-£4-(4-piridil) piperazin-1-il-|fenoksi|bütirik asit. TR199700020T1 (tr)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/457,538 US5652242A (en)	1993-03-29	1995-06-01	Heterocyclic derivatives
GBGB9518188.9A GB9518188D0 (en)	1995-09-07	1995-09-07	Optically active derivative

Publications (1)

Publication Number	Publication Date
TR199700020T1 true TR199700020T1 (tr)	1997-04-22

Family

ID=26307696

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TR97/00020T TR199700020T1 (tr)	1995-06-01	1996-05-28	Selüler yapisma inhibitörü olarak (-)-(3R)-3-metil-4-£4-£4-(4-piridil) piperazin-1-il-\|fenoksi\|bütirik asit.

Country Status (31)

Country	Link
EP (1)	EP0796247A1 (nl)
JP (1)	JP2885941B2 (nl)
KR (1)	KR100245957B1 (nl)
AT (1)	AT406675B (nl)
AU (1)	AU710105B2 (nl)
BE (1)	BE1009520A5 (nl)
BR (1)	BR9606409A (nl)
CA (1)	CA2194397A1 (nl)
CH (1)	CH691808A5 (nl)
CZ (1)	CZ26997A3 (nl)
DE (1)	DE19680509T1 (nl)
DK (1)	DK10697A (nl)
ES (1)	ES2137886B1 (nl)
FI (1)	FI970393A0 (nl)
GB (1)	GB2304340B (nl)
GR (1)	GR1002702B (nl)
HU (1)	HUP9700274A3 (nl)
IE (1)	IE960405A1 (nl)
IL (1)	IL118477A0 (nl)
IT (1)	IT1290839B1 (nl)
LU (1)	LU90008B1 (nl)
MC (1)	MC2418A1 (nl)
MX (1)	MX9700379A (nl)
NL (1)	NL1003243C2 (nl)
NO (1)	NO307460B1 (nl)
NZ (1)	NZ308597A (nl)
PL (1)	PL318440A1 (nl)
SE (1)	SE510812C2 (nl)
SK (1)	SK13097A3 (nl)
TR (1)	TR199700020T1 (nl)
WO (1)	WO1996038416A1 (nl)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0100158A3 (en) *	1982-07-28	1985-03-27	The Upjohn Company	(3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters
GB8609630D0 (en) *	1986-04-19	1986-05-21	Pfizer Ltd	Anti-arrhythmia agents
WO1994022835A2 (en) *	1993-03-29	1994-10-13	Zeneca Limited	Heterocyclic compounds as platelet aggregation inhibitors
AU692438B2 (en) *	1993-03-29	1998-06-11	Astrazeneca Ab	Heterocyclic derivatives as platelet aggregation inhibitors

1996
- 1996-05-28 ES ES009750006A patent/ES2137886B1/es not_active Expired - Fee Related
- 1996-05-28 WO PCT/GB1996/001260 patent/WO1996038416A1/en not_active IP Right Cessation
- 1996-05-28 AU AU58272/96A patent/AU710105B2/en not_active Ceased
- 1996-05-28 MX MX9700379A patent/MX9700379A/es unknown
- 1996-05-28 GB GB9627127A patent/GB2304340B/en not_active Expired - Fee Related
- 1996-05-28 FI FI970393A patent/FI970393A0/fi unknown
- 1996-05-28 AT AT0900596A patent/AT406675B/de active
- 1996-05-28 PL PL96318440A patent/PL318440A1/xx unknown
- 1996-05-28 CA CA002194397A patent/CA2194397A1/en not_active Abandoned
- 1996-05-28 GR GR960100176A patent/GR1002702B/el not_active IP Right Cessation
- 1996-05-28 DE DE19680509T patent/DE19680509T1/de not_active Withdrawn
- 1996-05-28 EP EP96919906A patent/EP0796247A1/en not_active Withdrawn
- 1996-05-28 CZ CZ97269A patent/CZ26997A3/cs unknown
- 1996-05-28 BR BR9606409A patent/BR9606409A/pt not_active Application Discontinuation
- 1996-05-28 TR TR97/00020T patent/TR199700020T1/xx unknown
- 1996-05-28 HU HU9700274A patent/HUP9700274A3/hu unknown
- 1996-05-28 KR KR1019970700532A patent/KR100245957B1/ko not_active Expired - Fee Related
- 1996-05-28 SK SK130-97A patent/SK13097A3/sk unknown
- 1996-05-28 CH CH00224/97A patent/CH691808A5/de not_active IP Right Cessation
- 1996-05-28 JP JP8536281A patent/JP2885941B2/ja not_active Expired - Fee Related
- 1996-05-28 NZ NZ308597A patent/NZ308597A/en unknown
- 1996-05-29 MC MC2347A patent/MC2418A1/xx unknown
- 1996-05-30 IL IL11847796A patent/IL118477A0/xx unknown
- 1996-05-31 IE IE960405A patent/IE960405A1/en not_active IP Right Cessation
- 1996-05-31 BE BE9600491A patent/BE1009520A5/fr not_active IP Right Cessation
- 1996-05-31 IT IT96MI001113A patent/IT1290839B1/it active IP Right Grant
- 1996-05-31 NL NL1003243A patent/NL1003243C2/nl not_active IP Right Cessation
1997
- 1997-01-22 LU LU90008A patent/LU90008B1/fr active
- 1997-01-24 SE SE9700203A patent/SE510812C2/sv not_active IP Right Cessation
- 1997-01-30 DK DK010697A patent/DK10697A/da not_active Application Discontinuation
- 1997-01-31 NO NO970437A patent/NO307460B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
WO1996038416A1 (en)	1996-12-05
JPH09512836A (ja)	1997-12-22
FI970393A7 (fi)	1997-01-30
IT1290839B1 (it)	1998-12-14
AT406675B (de)	2000-07-25
EP0796247A1 (en)	1997-09-24
FI970393L (fi)	1997-01-30
NL1003243C2 (nl)	1996-12-04
GB2304340B (en)	1998-07-29
DK10697A (da)	1997-04-01
BE1009520A5 (fr)	1997-04-01
FI970393A0 (fi)	1997-01-30
HUP9700274A2 (hu)	1999-06-28
NO307460B1 (no)	2000-04-10
PL318440A1 (en)	1997-06-09
SE510812C2 (sv)	1999-06-28
IL118477A0 (en)	1996-09-12
CH691808A5 (de)	2001-10-31
DE19680509T1 (de)	1997-12-04
AU710105B2 (en)	1999-09-16
HU9700274D0 (en)	1997-04-28
MX9700379A (es)	1997-04-30
SE9700203L (sv)	1997-01-24
ES2137886B1 (es)	2000-08-16
LU90008B1 (fr)	1997-04-16
MC2418A1 (fr)	1997-05-23
CA2194397A1 (en)	1996-12-05
NZ308597A (en)	1998-11-25
KR970704689A (ko)	1997-09-06
BR9606409A (pt)	1997-09-30
ITMI961113A1 (it)	1997-12-01
SE9700203D0 (sv)	1997-01-24
CZ26997A3 (en)	1997-08-13
IE960405A1 (en)	1996-12-11
ES2137886A1 (es)	1999-12-16
NO970437D0 (no)	1997-01-31
GR1002702B (el)	1997-05-22
GB9627127D0 (en)	1997-02-19
GB2304340A (en)	1997-03-19
HUP9700274A3 (en)	2000-02-28
ITMI961113A0 (it)	1996-05-31
SK13097A3 (en)	1997-08-06
NO970437L (no)	1997-02-20
AU5827296A (en)	1996-12-18
ATA900596A (de)	1999-12-15
JP2885941B2 (ja)	1999-04-26
KR100245957B1 (ko)	2000-04-01

Publication	Publication Date	Title
MX9705005A (es)	1998-07-31	Inhibidores de la proteina de transferencia de trigliceridos microsomicos y metodo.
DE19680255T1 (de)	1997-06-05	Inhibitoren der Enzymaktivität von Rotamase
FI965019A7 (fi)	1996-12-13	Entsyymi-inhibiittoreita
NO974213L (no)	1997-12-04	Små-molekylære inhibitorer for rotamase-enzym-aktivitet
DK1114032T3 (da)	2004-08-16	4-aminosubstituerede-2-substituerede-1,2,3,4-tetrahydroquinoliner som CETB-inhibitorer
TR199501472A2 (tr)	1996-07-21	Matriks metaloproteaz inhibitörler.
NO20006717D0 (no)	2000-12-29	Proteaseinhibitorer
DK0925303T3 (da)	2003-02-24	Phosphinsyreamider som matrixmetalloproteaseinhibitorer
ID24626A (id)	2000-07-27	Turunan-turunan asam hidroksamat sebagai penghambat metaloprotease matriks (mmp)
NO993587L (no)	1999-09-22	Sulfonamid-metalloprotease-inhibitorer
FR2769318B1 (fr)	1999-12-10	Revetement hydrophobe notamment pour vitrage
TR199501451A2 (tr)	1996-07-21	2-£(2-alkoksi-6-trifluormetilpirimidin-4-il)-oksimetilen)\| -fenil-asetik asit türevleri, bunlarin üretilmesine mahsus usul ve ara ürünler ile bunlarin kullanilmasi.
NO991994D0 (no)	1999-04-27	Substituerte 4-bifenyl-4-hydroksysm°rsyrederivater som matriks-metalloproteaseinhibitorer
NO911459D0 (no)	1991-04-15	Anvendelse av metallion-komplekser som belegginhibitorer.
BR9610075A (pt)	1999-03-02	Inibidores prolil endopeptidase
TR199700020T1 (tr)	1997-04-22	Selüler yapisma inhibitörü olarak (-)-(3R)-3-metil-4-£4-£4-(4-piridil) piperazin-1-il-\|fenoksi\|bütirik asit.
TR199600607A2 (tr)	1997-02-21	Insektisidlerin iticiligini azaltmaya mahsus para-hidroksifenilasetik asit.
IT239603Y1 (it)	2001-03-05	Struttura di calzatura, particolarmente per pattini
NO965353D0 (no)	1996-12-13	3-amino-2-okso-1-piperidineddiksyrederivater som enzyminhibitorer
ITRM960100U3 (it)	1996-08-20	Pellicola effetto antico craquelures per contatto.
KR970000223A (ko)	1997-01-21	콜레스테롤 생합성 저해제
IT1275260B (it)	1997-07-31	Chiodo particolarmente per calzature
ITBO970676A0 (it)	1997-11-18	Metodo di piegatura, in particolare di fascette.
KR970703937A (ko)	1997-08-09	금속단백질 분해효소 억제제(Metallproteinase inhibitors)
TR27813A (tr)	1995-08-29	Koyulastirilmis asit mikroemülsiyon terkibi.