ATA900596A - (-)-(3r)-3-methyl-4-(4-(4-(4-pyridyl) piperazin-1-yl)phenoxy)buttersäure als zellulärer adhäsionsinhibitor - Google Patents

(-)-(3r)-3-methyl-4-(4-(4-(4-pyridyl) piperazin-1-yl)phenoxy)buttersäure als zellulärer adhäsionsinhibitor

Info

Publication number: ATA900596A
Authority: AT; Austria
Prior art keywords: piperazin; phenoxy; pyridyl; methyl; cellular adhesion
Prior art date: 1995-06-01

Application number

AT0900596A

Other languages

English (en)

Other versions

AT406675B (de

Original Assignee

Zeneca Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-01

Filing date

1996-05-28

Publication date

1999-12-15

1995-06-01 Priority claimed from US08/457,538 external-priority patent/US5652242A/en

1995-09-07 Priority claimed from GBGB9518188.9A external-priority patent/GB9518188D0/en

1996-05-28 Application filed by Zeneca Ltd filed Critical Zeneca Ltd

1999-12-15 Publication of ATA900596A publication Critical patent/ATA900596A/de

2000-07-25 Application granted granted Critical

2000-07-25 Publication of AT406675B publication Critical patent/AT406675B/de

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Hematology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT0900596A 1995-06-01 1996-05-28 (-)-(3r)-3-methyl-4-(4-(4-(4-pyridyl) piperazin-1-yl)phenoxy)buttersäure als zellulärer adhäsionsinhibitor AT406675B (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US08/457,538 US5652242A (en)	1993-03-29	1995-06-01	Heterocyclic derivatives
GBGB9518188.9A GB9518188D0 (en)	1995-09-07	1995-09-07	Optically active derivative
PCT/GB1996/001260 WO1996038416A1 (en)	1995-06-01	1996-05-28	(-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazin-1-yl]phenoxy} butyric acid as cellular adhesion inhibitor

Publications (2)

Publication Number	Publication Date
ATA900596A true ATA900596A (de)	1999-12-15
AT406675B AT406675B (de)	2000-07-25

Family

ID=26307696

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT0900596A AT406675B (de)	1995-06-01	1996-05-28	(-)-(3r)-3-methyl-4-(4-(4-(4-pyridyl) piperazin-1-yl)phenoxy)buttersäure als zellulärer adhäsionsinhibitor

Country Status (31)

Country	Link
EP (1)	EP0796247A1 (de)
JP (1)	JP2885941B2 (de)
KR (1)	KR100245957B1 (de)
AT (1)	AT406675B (de)
AU (1)	AU710105B2 (de)
BE (1)	BE1009520A5 (de)
BR (1)	BR9606409A (de)
CA (1)	CA2194397A1 (de)
CH (1)	CH691808A5 (de)
CZ (1)	CZ26997A3 (de)
DE (1)	DE19680509T1 (de)
DK (1)	DK10697A (de)
ES (1)	ES2137886B1 (de)
FI (1)	FI970393L (de)
GB (1)	GB2304340B (de)
GR (1)	GR1002702B (de)
HU (1)	HUP9700274A3 (de)
IE (1)	IE960405A1 (de)
IL (1)	IL118477A0 (de)
IT (1)	IT1290839B1 (de)
LU (1)	LU90008B1 (de)
MC (1)	MC2418A1 (de)
MX (1)	MX9700379A (de)
NL (1)	NL1003243C2 (de)
NO (1)	NO307460B1 (de)
NZ (1)	NZ308597A (de)
PL (1)	PL318440A1 (de)
SE (1)	SE510812C2 (de)
SK (1)	SK13097A3 (de)
TR (1)	TR199700020T1 (de)
WO (1)	WO1996038416A1 (de)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0100158A3 (de) *	1982-07-28	1985-03-27	The Upjohn Company	(3-Pyridinyl)-heteroalkarylalkanole, ihre Alkansäuren und ihre Ester
GB8609630D0 (en) *	1986-04-19	1986-05-21	Pfizer Ltd	Anti-arrhythmia agents
AU692439B2 (en) *	1993-03-29	1998-06-11	Zeneca Limited	Heterocyclic compounds as platelet aggregation inhibitors
PT825184E (pt) *	1993-03-29	2001-11-30	Astrazeneca Ab	Derivados heterociclicos como inibidores de agregacao de plaquetas

1996
- 1996-05-28 ES ES009750006A patent/ES2137886B1/es not_active Expired - Fee Related
- 1996-05-28 JP JP8536281A patent/JP2885941B2/ja not_active Expired - Fee Related
- 1996-05-28 MX MX9700379A patent/MX9700379A/es unknown
- 1996-05-28 PL PL96318440A patent/PL318440A1/xx unknown
- 1996-05-28 AU AU58272/96A patent/AU710105B2/en not_active Ceased
- 1996-05-28 CH CH00224/97A patent/CH691808A5/de not_active IP Right Cessation
- 1996-05-28 TR TR97/00020T patent/TR199700020T1/xx unknown
- 1996-05-28 AT AT0900596A patent/AT406675B/de active
- 1996-05-28 DE DE19680509T patent/DE19680509T1/de not_active Withdrawn
- 1996-05-28 KR KR1019970700532A patent/KR100245957B1/ko not_active IP Right Cessation
- 1996-05-28 BR BR9606409A patent/BR9606409A/pt not_active Application Discontinuation
- 1996-05-28 CZ CZ97269A patent/CZ26997A3/cs unknown
- 1996-05-28 HU HU9700274A patent/HUP9700274A3/hu unknown
- 1996-05-28 WO PCT/GB1996/001260 patent/WO1996038416A1/en not_active IP Right Cessation
- 1996-05-28 CA CA002194397A patent/CA2194397A1/en not_active Abandoned
- 1996-05-28 GR GR960100176A patent/GR1002702B/el not_active IP Right Cessation
- 1996-05-28 SK SK130-97A patent/SK13097A3/sk unknown
- 1996-05-28 GB GB9627127A patent/GB2304340B/en not_active Expired - Fee Related
- 1996-05-28 EP EP96919906A patent/EP0796247A1/de not_active Withdrawn
- 1996-05-28 NZ NZ308597A patent/NZ308597A/en unknown
- 1996-05-29 MC MC2347A patent/MC2418A1/xx unknown
- 1996-05-30 IL IL11847796A patent/IL118477A0/xx unknown
- 1996-05-31 NL NL1003243A patent/NL1003243C2/xx not_active IP Right Cessation
- 1996-05-31 IE IE960405A patent/IE960405A1/en not_active IP Right Cessation
- 1996-05-31 BE BE9600491A patent/BE1009520A5/fr not_active IP Right Cessation
- 1996-05-31 IT IT96MI001113A patent/IT1290839B1/it active IP Right Grant
1997
- 1997-01-22 LU LU90008A patent/LU90008B1/fr active
- 1997-01-24 SE SE9700203A patent/SE510812C2/sv not_active IP Right Cessation
- 1997-01-30 FI FI970393A patent/FI970393L/fi unknown
- 1997-01-30 DK DK010697A patent/DK10697A/da not_active Application Discontinuation
- 1997-01-31 NO NO970437A patent/NO307460B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI970393A0 (fi)	1997-01-30
BR9606409A (pt)	1997-09-30
AU5827296A (en)	1996-12-18
ES2137886B1 (es)	2000-08-16
SE510812C2 (sv)	1999-06-28
FI970393L (fi)	1997-01-30
IL118477A0 (en)	1996-09-12
GB9627127D0 (en)	1997-02-19
SE9700203D0 (sv)	1997-01-24
JPH09512836A (ja)	1997-12-22
NO307460B1 (no)	2000-04-10
CA2194397A1 (en)	1996-12-05
ITMI961113A1 (it)	1997-12-01
IE960405A1 (en)	1996-12-11
WO1996038416A1 (en)	1996-12-05
AT406675B (de)	2000-07-25
EP0796247A1 (de)	1997-09-24
DK10697A (da)	1997-04-01
HU9700274D0 (en)	1997-04-28
CZ26997A3 (en)	1997-08-13
MC2418A1 (fr)	1997-05-23
NZ308597A (en)	1998-11-25
AU710105B2 (en)	1999-09-16
MX9700379A (es)	1997-04-30
GB2304340A (en)	1997-03-19
GB2304340B (en)	1998-07-29
IT1290839B1 (it)	1998-12-14
NO970437L (no)	1997-02-20
JP2885941B2 (ja)	1999-04-26
ES2137886A1 (es)	1999-12-16
SK13097A3 (en)	1997-08-06
SE9700203L (sv)	1997-01-24
LU90008B1 (fr)	1997-04-16
BE1009520A5 (fr)	1997-04-01
DE19680509T1 (de)	1997-12-04
CH691808A5 (de)	2001-10-31
HUP9700274A3 (en)	2000-02-28
HUP9700274A2 (hu)	1999-06-28
KR100245957B1 (ko)	2000-04-01
PL318440A1 (en)	1997-06-09
TR199700020T1 (tr)	1997-04-22
NO970437D0 (no)	1997-01-31
GR1002702B (el)	1997-05-22
NL1003243C2 (nl)	1996-12-04
KR970704689A (ko)	1997-09-06
ITMI961113A0 (it)	1996-05-31

Publication	Publication Date	Title
DE19680255T1 (de)	1997-06-05	Inhibitoren der Enzymaktivität von Rotamase
MX9906600A (es)	1999-10-31	4-(3-heterociclil-1-benzoil)pirazoles
DK0925287T3 (da)	2003-05-12	Heterocykliske metalloproteaseinhibitorer
ID22982A (id)	1999-12-23	PIRAZOL-PIRAZOL TERSUBSTITUSI SEBAGAI INHIBITOR KINASE p38
DE60236161D1 (de)	2010-06-10	Automatische identifizierung von klangaufzeichnungen
NO972307D0 (no)	1997-05-21	Matriksmetallproteaseinhibitorer
ATE226573T1 (de)	2002-11-15	Heterozyklische metalloproteaseinhibitoren
FI973282A0 (fi)	1997-08-08	Trombiinin inhibiittoreita
DK1027332T3 (da)	2004-10-04	Hidtil ukendte lactametalloproteaseinhibitorer
IT1298163B1 (it)	1999-12-20	Inibitori di solfammido-metalloproteasi
DK0858464T3 (da)	2003-08-25	Thrombin-inhibitorer
EE9800044A (et)	1998-08-17	Prolüülendopeptidaasi inhibiitorid
ATA900596A (de)	1999-12-15	(-)-(3r)-3-methyl-4-(4-(4-(4-pyridyl) piperazin-1-yl)phenoxy)buttersäure als zellulärer adhäsionsinhibitor
DE69800370D1 (de)	2000-12-07	4-(Alkoxyhydroxy)styryl-triazin Photoinitiatoren
AR053675A2 (es)	2007-05-16	Composicion herbicida
ATE198208T1 (de)	2001-01-15	Aus imidazo-(1,5a)-pyridin stammende inhibitoren von serinproteasen
DE59811763D1 (de)	2004-09-09	Substituierte 4-(3-alkenyl-benzoyl)-pyrazole
GB9610093D0 (en)	1996-07-17	(-)-(3R)-methyl-4-[4-[4-(4-pyridyl) piperazin-1-yl] phenoxy] butyric acid
ZA964509B (en)	1996-12-02	(-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazin-1-yl]phenoxy}butyric acid
FI955916L (fi)	1995-12-08	N-((1-(4-(4-fluorifenoksi)butyyli)-4-piperidinyyli)-N-metyyliamino)-2-bentsotiatsololeja luokan III rytmihäiriölääkkeinä
NO940997D0 (no)	1994-03-18	Guanidinyl-substituerte heterocykliske trombin-inhibitorer