NO970437D0 - (-)-(3R)-3-metyl-4-{4-£4-(4-pyridyl) piperazin-1-yl|fenoksy} smörsyre som cellulær adhesjonsinhibitor - Google Patents

(-)-(3R)-3-metyl-4-{4-£4-(4-pyridyl) piperazin-1-yl|fenoksy} smörsyre som cellulær adhesjonsinhibitor

Info

Publication number: NO970437D0
Authority: NO; Norway
Prior art keywords: piperazin; phenoxy; pyridyl; methyl; butyric acid
Prior art date: 1995-06-01

Application number

NO970437A

Other languages

English (en)

Other versions

NO307460B1 (no

NO970437L (no

Inventor

Stuart Dennett Mills

Original Assignee

Zeneca Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-01

Filing date

1997-01-31

Publication date

1997-01-31

1995-06-01 Priority claimed from US08/457,538 external-priority patent/US5652242A/en

1995-09-07 Priority claimed from GBGB9518188.9A external-priority patent/GB9518188D0/en

1997-01-31 Application filed by Zeneca Ltd filed Critical Zeneca Ltd

1997-01-31 Publication of NO970437D0 publication Critical patent/NO970437D0/no

1997-02-20 Publication of NO970437L publication Critical patent/NO970437L/no

2000-04-10 Publication of NO307460B1 publication Critical patent/NO307460B1/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Hematology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyridine Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO970437A 1995-06-01 1997-01-31 Optiske aktive forbindelser, fremgangsmõte for fremstilling derav, farmasøytisk blanding og anvendelse derav NO307460B1 (no)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US08/457,538 US5652242A (en)	1993-03-29	1995-06-01	Heterocyclic derivatives
GBGB9518188.9A GB9518188D0 (en)	1995-09-07	1995-09-07	Optically active derivative
PCT/GB1996/001260 WO1996038416A1 (en)	1995-06-01	1996-05-28	(-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazin-1-yl]phenoxy} butyric acid as cellular adhesion inhibitor

Publications (3)

Publication Number	Publication Date
NO970437D0 true NO970437D0 (no)	1997-01-31
NO970437L NO970437L (no)	1997-02-20
NO307460B1 NO307460B1 (no)	2000-04-10

Family

ID=26307696

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO970437A NO307460B1 (no)	1995-06-01	1997-01-31	Optiske aktive forbindelser, fremgangsmõte for fremstilling derav, farmasøytisk blanding og anvendelse derav

Country Status (31)

Country	Link
EP (1)	EP0796247A1 (no)
JP (1)	JP2885941B2 (no)
KR (1)	KR100245957B1 (no)
AT (1)	AT406675B (no)
AU (1)	AU710105B2 (no)
BE (1)	BE1009520A5 (no)
BR (1)	BR9606409A (no)
CA (1)	CA2194397A1 (no)
CH (1)	CH691808A5 (no)
CZ (1)	CZ26997A3 (no)
DE (1)	DE19680509T1 (no)
DK (1)	DK10697A (no)
ES (1)	ES2137886B1 (no)
FI (1)	FI970393L (no)
GB (1)	GB2304340B (no)
GR (1)	GR1002702B (no)
HU (1)	HUP9700274A3 (no)
IE (1)	IE960405A1 (no)
IL (1)	IL118477A0 (no)
IT (1)	IT1290839B1 (no)
LU (1)	LU90008B1 (no)
MC (1)	MC2418A1 (no)
MX (1)	MX9700379A (no)
NL (1)	NL1003243C2 (no)
NO (1)	NO307460B1 (no)
NZ (1)	NZ308597A (no)
PL (1)	PL318440A1 (no)
SE (1)	SE510812C2 (no)
SK (1)	SK13097A3 (no)
TR (1)	TR199700020T1 (no)
WO (1)	WO1996038416A1 (no)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0100158A3 (en) *	1982-07-28	1985-03-27	The Upjohn Company	(3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters
GB8609630D0 (en) *	1986-04-19	1986-05-21	Pfizer Ltd	Anti-arrhythmia agents
AU692439B2 (en) *	1993-03-29	1998-06-11	Zeneca Limited	Heterocyclic compounds as platelet aggregation inhibitors
PT825184E (pt) *	1993-03-29	2001-11-30	Astrazeneca Ab	Derivados heterociclicos como inibidores de agregacao de plaquetas

1996
- 1996-05-28 ES ES009750006A patent/ES2137886B1/es not_active Expired - Fee Related
- 1996-05-28 JP JP8536281A patent/JP2885941B2/ja not_active Expired - Fee Related
- 1996-05-28 MX MX9700379A patent/MX9700379A/es unknown
- 1996-05-28 PL PL96318440A patent/PL318440A1/xx unknown
- 1996-05-28 AU AU58272/96A patent/AU710105B2/en not_active Ceased
- 1996-05-28 CH CH00224/97A patent/CH691808A5/de not_active IP Right Cessation
- 1996-05-28 TR TR97/00020T patent/TR199700020T1/xx unknown
- 1996-05-28 AT AT0900596A patent/AT406675B/de active
- 1996-05-28 DE DE19680509T patent/DE19680509T1/de not_active Withdrawn
- 1996-05-28 KR KR1019970700532A patent/KR100245957B1/ko not_active IP Right Cessation
- 1996-05-28 BR BR9606409A patent/BR9606409A/pt not_active Application Discontinuation
- 1996-05-28 CZ CZ97269A patent/CZ26997A3/cs unknown
- 1996-05-28 HU HU9700274A patent/HUP9700274A3/hu unknown
- 1996-05-28 WO PCT/GB1996/001260 patent/WO1996038416A1/en not_active IP Right Cessation
- 1996-05-28 CA CA002194397A patent/CA2194397A1/en not_active Abandoned
- 1996-05-28 GR GR960100176A patent/GR1002702B/el not_active IP Right Cessation
- 1996-05-28 SK SK130-97A patent/SK13097A3/sk unknown
- 1996-05-28 GB GB9627127A patent/GB2304340B/en not_active Expired - Fee Related
- 1996-05-28 EP EP96919906A patent/EP0796247A1/en not_active Withdrawn
- 1996-05-28 NZ NZ308597A patent/NZ308597A/en unknown
- 1996-05-29 MC MC2347A patent/MC2418A1/xx unknown
- 1996-05-30 IL IL11847796A patent/IL118477A0/xx unknown
- 1996-05-31 NL NL1003243A patent/NL1003243C2/xx not_active IP Right Cessation
- 1996-05-31 IE IE960405A patent/IE960405A1/en not_active IP Right Cessation
- 1996-05-31 BE BE9600491A patent/BE1009520A5/fr not_active IP Right Cessation
- 1996-05-31 IT IT96MI001113A patent/IT1290839B1/it active IP Right Grant
1997
- 1997-01-22 LU LU90008A patent/LU90008B1/fr active
- 1997-01-24 SE SE9700203A patent/SE510812C2/sv not_active IP Right Cessation
- 1997-01-30 FI FI970393A patent/FI970393L/fi unknown
- 1997-01-30 DK DK010697A patent/DK10697A/da not_active Application Discontinuation
- 1997-01-31 NO NO970437A patent/NO307460B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI970393A0 (fi)	1997-01-30
BR9606409A (pt)	1997-09-30
AU5827296A (en)	1996-12-18
ES2137886B1 (es)	2000-08-16
SE510812C2 (sv)	1999-06-28
FI970393L (fi)	1997-01-30
IL118477A0 (en)	1996-09-12
GB9627127D0 (en)	1997-02-19
SE9700203D0 (sv)	1997-01-24
JPH09512836A (ja)	1997-12-22
NO307460B1 (no)	2000-04-10
CA2194397A1 (en)	1996-12-05
ITMI961113A1 (it)	1997-12-01
IE960405A1 (en)	1996-12-11
WO1996038416A1 (en)	1996-12-05
AT406675B (de)	2000-07-25
EP0796247A1 (en)	1997-09-24
DK10697A (da)	1997-04-01
HU9700274D0 (en)	1997-04-28
CZ26997A3 (en)	1997-08-13
MC2418A1 (fr)	1997-05-23
NZ308597A (en)	1998-11-25
AU710105B2 (en)	1999-09-16
MX9700379A (es)	1997-04-30
GB2304340A (en)	1997-03-19
GB2304340B (en)	1998-07-29
IT1290839B1 (it)	1998-12-14
NO970437L (no)	1997-02-20
JP2885941B2 (ja)	1999-04-26
ES2137886A1 (es)	1999-12-16
SK13097A3 (en)	1997-08-06
SE9700203L (sv)	1997-01-24
LU90008B1 (fr)	1997-04-16
BE1009520A5 (fr)	1997-04-01
DE19680509T1 (de)	1997-12-04
CH691808A5 (de)	2001-10-31
HUP9700274A3 (en)	2000-02-28
HUP9700274A2 (hu)	1999-06-28
KR100245957B1 (ko)	2000-04-01
ATA900596A (de)	1999-12-15
PL318440A1 (en)	1997-06-09
TR199700020T1 (tr)	1997-04-22
GR1002702B (el)	1997-05-22
NL1003243C2 (nl)	1996-12-04
KR970704689A (ko)	1997-09-06
ITMI961113A0 (it)	1996-05-31

Publication	Publication Date	Title
DK1036062T3 (da)	2004-04-05	Hydroxamsyrederivater som matrix metalloprotease (MMP) inhibitorer
FI973974L (fi)	1997-10-16	Aryylisulfonyylihydroksaamihappojohdannaisia MMP- ja TNF-inhibiittoreina
NO973764L (no)	1997-10-15	Nye dipeptidamidiner som trombin-inhibitorer
FI965156L (fi)	1996-12-20	Aryylisulfonamido-substituoidut hydroksaamihapot matriisimetalloproteinaasi-inhibiittoreina
DK0925303T3 (da)	2003-02-24	Phosphinsyreamider som matrixmetalloproteaseinhibitorer
NO20010686D0 (no)	2001-02-09	Hydroksypipecolathydroksaminsyrederivater som MMP inhibitorer
FI970430L (fi)	1997-04-01	Atsa-asparaziinihappo analogeja 1-beta-interleukiinia muuttavan entsyymin inhibiittoreina
NO993587D0 (no)	1999-07-22	Sulfonamid-metalloprotease-inhibitorer
DK0934259T3 (da)	2003-01-27	Beta-sulfonamidohydroxamsyrer som matrixmetalloproteinase- og TACE-inhibitorer
NO20013675D0 (no)	2001-07-26	2,3,4,5-Tetrahydro-1H-[1,4)benzodiazepin-3-hydroksamsyre som matriks-metalloproteinaseinhibitorer
NO991994L (no)	1999-06-15	Substituerte 4-bifenyl-4-hydroksysm°rsyrederivater som matriksmetalloproteaseinhibitorer
NO911459D0 (no)	1991-04-15	Anvendelse av metallion-komplekser som belegginhibitorer.
NO970437L (no)	1997-02-20	(-)-(3R)-3-metyl-4-{4-£4-(4-pyridyl) piperazin-1-yl\|fenoksy} smörsyre som cellulær adhesjonsinhibitor
GB9610093D0 (en)	1996-07-17	(-)-(3R)-methyl-4-[4-[4-(4-pyridyl) piperazin-1-yl] phenoxy] butyric acid
ZA964509B (en)	1996-12-02	(-)-(3r)-3-methyl-4-{4-[4-(4-pyridyl)piperazin-1-yl]phenoxy}butyric acid
NO965353D0 (no)	1996-12-13	3-amino-2-okso-1-piperidineddiksyrederivater som enzyminhibitorer
NO950212L (no)	1995-03-16	Indolinyl-N-hydroksyurinstoff- og -N-hydroksamsyrederivater som lipoksygenase-inhibitorer
NO986204L (no)	1998-12-30	4-(4-oksosyklheksyl)benzamider som mellomprodukter for medikamenter
ID18481A (id)	1998-04-09	2-(3,5-difluorofenil)-3-(4-metilsulfonil)fenil)-2-siklopenten-1-on yang berguna sebagai inhibitor cox-2

Legal Events

Date	Code	Title	Description
2002-12-30	MM1K	Lapsed by not paying the annual fees	Free format text: LAPSED IN NOVEMBER 2002