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SK282265B6 - Polypeptid mpl ligandu, jeho zodpovedajúca nukleová kyselina, expresný vektor a hostiteľská bunka, ktorá ho obsahuje, spôsob prípravy polypeptidu a jeho použitie - Google Patents

Polypeptid mpl ligandu, jeho zodpovedajúca nukleová kyselina, expresný vektor a hostiteľská bunka, ktorá ho obsahuje, spôsob prípravy polypeptidu a jeho použitie Download PDF

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Publication number
SK282265B6
SK282265B6 SK875-96A SK87596A SK282265B6 SK 282265 B6 SK282265 B6 SK 282265B6 SK 87596 A SK87596 A SK 87596A SK 282265 B6 SK282265 B6 SK 282265B6
Authority
SK
Slovakia
Prior art keywords
mpl ligand
mpl
dna
cells
polypeptide
Prior art date
Application number
SK875-96A
Other languages
English (en)
Slovak (sk)
Other versions
SK87596A3 (en
Inventor
Dan L. Eaton
Savuage Frederic J. De
Original Assignee
Genentech, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/196,689 external-priority patent/US8357513B1/en
Priority claimed from US08/249,376 external-priority patent/US8192955B1/en
Priority claimed from US08/348,657 external-priority patent/US6660256B1/en
Application filed by Genentech, Inc. filed Critical Genentech, Inc.
Publication of SK87596A3 publication Critical patent/SK87596A3/sk
Publication of SK282265B6 publication Critical patent/SK282265B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/524—Thrombopoietin, i.e. C-MPL ligand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Information Transfer Systems (AREA)
  • Vehicle Body Suspensions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
SK875-96A 1994-01-03 1994-12-28 Polypeptid mpl ligandu, jeho zodpovedajúca nukleová kyselina, expresný vektor a hostiteľská bunka, ktorá ho obsahuje, spôsob prípravy polypeptidu a jeho použitie SK282265B6 (sk)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US17655394A 1994-01-03 1994-01-03
US18560794A 1994-01-21 1994-01-21
US08/196,689 US8357513B1 (en) 1994-01-03 1994-02-15 Nucleic acids encoding mpl ligand (thrombopoietin) and fragments thereof
US22326394A 1994-04-04 1994-04-04
US08/249,376 US8192955B1 (en) 1994-01-03 1994-05-25 Nucleic acids encoding MPL ligand (thrombopoietin), variants, and fragments thereof
US34865894A 1994-12-02 1994-12-02
US08/348,657 US6660256B1 (en) 1994-01-03 1994-12-02 Porcine mpl ligand
PCT/US1994/014553 WO1995018858A1 (en) 1994-01-03 1994-12-28 Thrombopoietin

Publications (2)

Publication Number Publication Date
SK87596A3 SK87596A3 (en) 1997-11-05
SK282265B6 true SK282265B6 (sk) 2001-12-03

Family

ID=27569151

Family Applications (1)

Application Number Title Priority Date Filing Date
SK875-96A SK282265B6 (sk) 1994-01-03 1994-12-28 Polypeptid mpl ligandu, jeho zodpovedajúca nukleová kyselina, expresný vektor a hostiteľská bunka, ktorá ho obsahuje, spôsob prípravy polypeptidu a jeho použitie

Country Status (28)

Country Link
EP (1) EP0738323A1 (lv)
JP (2) JPH09508262A (lv)
CN (1) CN1134539C (lv)
AU (1) AU704266B2 (lv)
BG (1) BG63639B1 (lv)
CA (1) CA2178482C (lv)
CZ (1) CZ296130B6 (lv)
DK (1) DK149194A (lv)
ES (1) ES2114786B1 (lv)
FI (1) FI121573B (lv)
FR (1) FR2714670B1 (lv)
GB (1) GB2285446B (lv)
HR (1) HRP941020A2 (lv)
HU (1) HUT75657A (lv)
IE (1) IE72517B1 (lv)
IL (1) IL112184A (lv)
IT (1) IT1283770B1 (lv)
LU (1) LU88573A1 (lv)
LV (1) LV11632B (lv)
NL (1) NL9500010A (lv)
NO (1) NO326903B1 (lv)
NZ (1) NZ278726A (lv)
PT (1) PT101627B (lv)
RO (1) RO117110B1 (lv)
SG (1) SG47030A1 (lv)
SI (1) SI9420079A (lv)
SK (1) SK282265B6 (lv)
WO (1) WO1995018858A1 (lv)

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US5989538A (en) * 1995-02-15 1999-11-23 Amgen Inc. Mpl ligand analogs
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US6660843B1 (en) 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
CZ302155B6 (cs) 1998-10-23 2010-11-18 Kirin-Amgen Inc. Sloucenina, která se váže na mpl receptor, zpusob její výroby, farmaceutická kompozice s jejím obsahem, polynukleotid, vektor a hostitelská bunka
CY2010012I2 (el) * 2000-05-25 2020-05-29 Novartis Ag Μιμητικα θρομβοποιητινης
UY26317A1 (es) * 2000-08-30 2000-10-31 Alfonso Cayota Carlos Pritsch Sistema de produccion de trombopoyetina humana por celulas de mamiferos en cultivo
US6673580B2 (en) 2000-10-27 2004-01-06 Genentech, Inc. Identification and modification of immunodominant epitopes in polypeptides
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Also Published As

Publication number Publication date
IE950002A1 (en) 1995-07-12
IE72517B1 (en) 1997-04-23
HU9601805D0 (en) 1996-08-28
CA2178482C (en) 2012-01-03
FI962723L (fi) 1996-09-03
GB2285446A (en) 1995-07-12
BG100693A (en) 1998-01-30
NL9500010A (nl) 1995-08-01
ITTO950002A1 (it) 1995-07-03
GB9425831D0 (en) 1995-02-22
IT1283770B1 (it) 1998-04-30
LV11632A (lv) 1996-12-20
CN1141061A (zh) 1997-01-22
NO962783L (no) 1996-09-03
AU1514695A (en) 1995-08-01
CN1134539C (zh) 2004-01-14
BG63639B1 (bg) 2002-07-31
DK149194A (da) 1995-07-04
CZ296130B6 (cs) 2006-01-11
FR2714670B1 (fr) 1997-01-10
RO117110B1 (ro) 2001-10-30
GB2285446B (en) 1999-07-28
NZ278726A (en) 1998-06-26
NO326903B1 (no) 2009-03-16
HUT75657A (en) 1997-05-28
FI962723A0 (fi) 1996-07-02
NO962783D0 (no) 1996-07-02
AU704266B2 (en) 1999-04-15
LU88573A1 (de) 1995-06-01
CZ192296A3 (en) 1997-05-14
SG47030A1 (en) 1998-03-20
ES2114786B1 (es) 1999-01-01
PT101627A (pt) 1995-11-30
CA2178482A1 (en) 1995-07-13
IL112184A0 (en) 1995-03-15
FI121573B (fi) 2011-01-14
SI9420079A (en) 1997-02-28
PT101627B (pt) 1996-11-29
ES2114786A1 (es) 1998-06-01
LV11632B (en) 1997-04-20
HRP941020A2 (en) 1997-04-30
WO1995018858A1 (en) 1995-07-13
SK87596A3 (en) 1997-11-05
EP0738323A1 (en) 1996-10-23
JPH10113186A (ja) 1998-05-06
IL112184A (en) 2004-07-25
JPH09508262A (ja) 1997-08-26
FR2714670A1 (fr) 1995-07-07
ITTO950002A0 (it) 1995-01-02

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Legal Events

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MK4A Expiry of patent

Expiry date: 20141228