SI1771474T1 - Inhibitorji angiopoetinu podobnega proteina kombinacije in njihova uporaba - Google Patents
Inhibitorji angiopoetinu podobnega proteina kombinacije in njihova uporabaInfo
- Publication number
- SI1771474T1 SI1771474T1 SI200530979T SI200530979T SI1771474T1 SI 1771474 T1 SI1771474 T1 SI 1771474T1 SI 200530979 T SI200530979 T SI 200530979T SI 200530979 T SI200530979 T SI 200530979T SI 1771474 T1 SI1771474 T1 SI 1771474T1
- Authority
- SI
- Slovenia
- Prior art keywords
- angiopoietin
- protein
- combinations
- inhibitors
- cancer
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Cardiology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Ophthalmology & Optometry (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Neurosurgery (AREA)
- Zoology (AREA)
- Pulmonology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58978204P | 2004-07-20 | 2004-07-20 | |
PCT/US2005/025734 WO2006014729A2 (en) | 2004-07-20 | 2005-07-19 | Inhibitors of angiopoietin-like 4 protein, combinations, and their use |
EP05790352A EP1771474B1 (en) | 2004-07-20 | 2005-07-19 | Inhibitors of angiopoietin-like 4 protein, combinations, and their use |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1771474T1 true SI1771474T1 (sl) | 2010-06-30 |
Family
ID=35787710
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200530979T SI1771474T1 (sl) | 2004-07-20 | 2005-07-19 | Inhibitorji angiopoetinu podobnega proteina kombinacije in njihova uporaba |
Country Status (23)
Country | Link |
---|---|
US (2) | US7740846B2 (sl) |
EP (3) | EP1771474B1 (sl) |
JP (2) | JP4947717B2 (sl) |
KR (1) | KR101254815B1 (sl) |
CN (2) | CN102641503A (sl) |
AT (1) | ATE456579T1 (sl) |
AU (2) | AU2005269716B2 (sl) |
BR (1) | BRPI0513534A (sl) |
CA (1) | CA2574758A1 (sl) |
CY (1) | CY1109931T1 (sl) |
DE (1) | DE602005019167D1 (sl) |
DK (1) | DK1771474T3 (sl) |
ES (1) | ES2339789T3 (sl) |
IL (1) | IL180725A0 (sl) |
MX (1) | MX2007000784A (sl) |
NO (1) | NO20070951L (sl) |
NZ (1) | NZ552956A (sl) |
PL (1) | PL1771474T3 (sl) |
PT (1) | PT1771474E (sl) |
RU (1) | RU2392966C2 (sl) |
SI (1) | SI1771474T1 (sl) |
WO (1) | WO2006014729A2 (sl) |
ZA (1) | ZA200701183B (sl) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6582959B2 (en) * | 1991-03-29 | 2003-06-24 | Genentech, Inc. | Antibodies to vascular endothelial cell growth factor |
US20050123925A1 (en) | 2002-11-15 | 2005-06-09 | Genentech, Inc. | Compositions and methods for the diagnosis and treatment of tumor |
WO2005007819A2 (en) | 2003-07-09 | 2005-01-27 | Wisconsin Alumni Research Foundation | Charge-dynamic polymers and delivery of anionic compounds |
US8604185B2 (en) | 2004-07-20 | 2013-12-10 | Genentech, Inc. | Inhibitors of angiopoietin-like 4 protein, combinations, and their use |
CN101080419B (zh) * | 2004-07-20 | 2014-07-02 | 健泰科生物技术公司 | 利用血管生成素样4蛋白的组合物和方法 |
SI1771474T1 (sl) | 2004-07-20 | 2010-06-30 | Genentech Inc | Inhibitorji angiopoetinu podobnega proteina kombinacije in njihova uporaba |
WO2006074228A1 (en) * | 2005-01-07 | 2006-07-13 | Lexicon Pharmaceuticals, Inc. | Monoclonal antibodies against angiopoietin-like protein 4 (angptl4 ) |
US8734851B2 (en) * | 2005-04-29 | 2014-05-27 | Wisconsin Alumni Research Foundation | Localized delivery of nucleic acid by polyelectrolyte assemblies |
BRPI0710645A2 (pt) | 2006-04-07 | 2012-03-20 | The Procter & Gamble Company | Anticorpos que se ligam à proteína humana tirosina fosfatase beta (hptpbeta) e usos dos mesmos |
US7622593B2 (en) | 2006-06-27 | 2009-11-24 | The Procter & Gamble Company | Human protein tyrosine phosphatase inhibitors and methods of use |
KR100962301B1 (ko) * | 2006-11-03 | 2010-06-11 | 재단법인서울대학교산학협력재단 | 자궁경부암을 위한 치료용 조성물 |
DK2101807T3 (en) * | 2006-12-19 | 2016-08-29 | Genentech Inc | VEGF-SPECIFIC ANTAGONISTS FOR ADMINISTRATIVE AND NEOADVERTIVE TREATMENT AND TREATMENT OF TEMPERATURES IN EARLY STAGE |
US8834918B2 (en) * | 2007-01-22 | 2014-09-16 | Wisconsin Alumni Research Foundation | Modified multilayered film |
JP2010532385A (ja) * | 2007-07-02 | 2010-10-07 | ユ,ミン | 複合的癌治療の方法、組成物および標的 |
WO2009049100A2 (en) * | 2007-10-09 | 2009-04-16 | Wisconsin Alumni Research Foundation | Ultrathin multilayered films for controlled release of anionic reagents |
US8126437B1 (en) | 2008-01-24 | 2012-02-28 | Invent Again | Ubiquitous voice messaging |
US8324333B2 (en) | 2008-06-05 | 2012-12-04 | Wisconsin Alumni Research Foundation | Anionic charge-dynamic polymers for release of cationic agents |
AP2011005541A0 (en) * | 2008-07-16 | 2011-02-28 | Baylor Res Inst | HIV vaccine based on targeting maximized GAG and NEF to dendritic cells. |
PL2361085T5 (pl) | 2008-11-22 | 2018-12-31 | F.Hoffmann-La Roche Ag | Zastosowanie przeciwciała anty-vegf w połączeniu z chemioterapią w leczeniu raka sutka |
CN102365024A (zh) | 2009-07-06 | 2012-02-29 | 阿克比治疗有限公司 | 用于防止癌细胞转移的化合物、组合物和方法 |
US20120207770A1 (en) | 2009-10-14 | 2012-08-16 | Nanyang Technological University | Antiproliferative agent |
CA2786071C (en) | 2010-01-08 | 2021-01-12 | Isis Pharmaceuticals, Inc. | Modulation of angiopoietin-like 3 expression |
US9475850B2 (en) | 2010-06-05 | 2016-10-25 | The Uab Research Foundation | Methods for treatment of nephrotic syndrome and related conditions |
US9139629B2 (en) | 2010-06-05 | 2015-09-22 | The Uab Research Foundation | Methods for treatment of nephrotic syndrome and related conditions |
CA2803675A1 (en) * | 2010-07-12 | 2012-01-19 | Threshold Pharmaceuticals, Inc. | Administration of hypoxia activated prodrugs and antiangiogenic agents for the treatment of cancer |
US20140004209A1 (en) | 2010-12-22 | 2014-01-02 | Genentech, Inc. | Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms |
JP6270719B2 (ja) | 2011-07-22 | 2018-01-31 | パシレックス・ファーマシューティカルズ・インコーポレイテッド | 合成致死性および癌の治療 |
US20140242084A1 (en) * | 2011-08-08 | 2014-08-28 | Nanyang Technological University | Angiopoietin-Like 4 and Its Use in Modulating Cell Leakiness |
CN104039351A (zh) | 2011-10-13 | 2014-09-10 | 阿尔皮奥治疗学股份有限公司 | 用于治疗血管渗漏综合征和癌症的方法 |
KR102427777B1 (ko) | 2012-06-26 | 2022-08-01 | 델 마 파마슈티컬스 | 디안하이드로갈락티톨, 디아세틸디안하이드로갈락티톨, 디브로모둘시톨, 또는 그의 유사체 또는 유도체를 이용하여 유전학적 다형성이 있는 환자에 있어서 티로신-키나아제-억제제 내성 악성종양, ahi1 조절곤란 또는 돌연변이를 치료하는 방법 |
EP2885319B1 (en) * | 2012-08-14 | 2019-10-09 | Nanyang Technological University | Angiopoietin-like 4 antibody and a method of its use in cancer treatment |
US9259435B2 (en) | 2012-08-31 | 2016-02-16 | W. L. Gore & Associates, Inc. | Reactive oxidative species generating materials and methods of use |
EP2914261B1 (en) * | 2012-10-30 | 2020-12-16 | Pacylex Pharmaceuticals Inc. | Synthetic lethality and the treatment of cancer |
KR101407730B1 (ko) * | 2012-11-23 | 2014-06-12 | 인하대학교 산학협력단 | 안지오포이에틴-4 단백질을 유효성분으로 포함하는 발기부전의 예방 또는 치료용 조성물 |
GB201301313D0 (en) | 2013-01-25 | 2013-03-06 | Univ Singapore | Respiratory Tract Infections |
US20150050277A1 (en) | 2013-03-15 | 2015-02-19 | Aerpio Therapeutics Inc. | Compositions and methods for treating ocular diseases |
JP2016519684A (ja) | 2013-04-08 | 2016-07-07 | デニス エム ブラウン | 準最適に投与された薬物療法の有効性を改善するための及び/又は副作用を低減するための方法および組成物 |
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- 2005-07-19 PL PL05790352T patent/PL1771474T3/pl unknown
- 2005-07-19 DK DK05790352.8T patent/DK1771474T3/da active
- 2005-07-19 CA CA002574758A patent/CA2574758A1/en not_active Abandoned
- 2005-07-19 US US11/185,215 patent/US7740846B2/en active Active
- 2005-07-19 PT PT05790352T patent/PT1771474E/pt unknown
- 2005-07-19 EP EP09013335A patent/EP2172482A1/en not_active Withdrawn
- 2005-07-19 AT AT05790352T patent/ATE456579T1/de active
- 2005-07-19 ZA ZA200701183A patent/ZA200701183B/en unknown
- 2005-07-19 KR KR1020077003872A patent/KR101254815B1/ko active IP Right Grant
-
2006
- 2006-09-28 US US11/540,884 patent/US20070026002A1/en not_active Abandoned
-
2007
- 2007-01-16 IL IL180725A patent/IL180725A0/en unknown
- 2007-02-19 NO NO20070951A patent/NO20070951L/no not_active Application Discontinuation
-
2010
- 2010-03-30 CY CY20101100299T patent/CY1109931T1/el unknown
-
2011
- 2011-03-30 AU AU2011201436A patent/AU2011201436A1/en not_active Withdrawn
- 2011-08-10 JP JP2011175420A patent/JP2012017331A/ja not_active Withdrawn
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