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RU2346948C2 - ПРОИЗВОДНЫЕ 1-α-ГАЛОГЕН-2,2-ДИФТОР-2-ДЕЗОКСИ-D-РИБОФУРАНОЗЫ И СПОСОБ ИХ ПОЛУЧЕНИЯ - Google Patents

ПРОИЗВОДНЫЕ 1-α-ГАЛОГЕН-2,2-ДИФТОР-2-ДЕЗОКСИ-D-РИБОФУРАНОЗЫ И СПОСОБ ИХ ПОЛУЧЕНИЯ Download PDF

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Publication number
RU2346948C2
RU2346948C2 RU2007107607/04A RU2007107607A RU2346948C2 RU 2346948 C2 RU2346948 C2 RU 2346948C2 RU 2007107607/04 A RU2007107607/04 A RU 2007107607/04A RU 2007107607 A RU2007107607 A RU 2007107607A RU 2346948 C2 RU2346948 C2 RU 2346948C2
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RU
Russia
Prior art keywords
formula
compound
halogen
iii
derivative
Prior art date
Application number
RU2007107607/04A
Other languages
English (en)
Russian (ru)
Other versions
RU2007107607A (ru
Inventor
Дзаехеон ЛИ (KR)
Дзаехеон Ли
Га Сеунг ПАРК (KR)
Га Сеунг ПАРК
Моонсуб ЛИ (KR)
Моонсуб ЛИ
Хан Кионг КИМ (KR)
Хан Кионг КИМ
Хио-Дзеонг БАНГ (KR)
Хио-Дзеонг БАНГ
Янг-Кил ЧАНГ (KR)
Янг-Кил Чанг
Гван Сун ЛИ (KR)
Гван Сун ЛИ
Original Assignee
Ханми Фарм. Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ханми Фарм. Ко., Лтд. filed Critical Ханми Фарм. Ко., Лтд.
Publication of RU2007107607A publication Critical patent/RU2007107607A/ru
Application granted granted Critical
Publication of RU2346948C2 publication Critical patent/RU2346948C2/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/08—Deoxysugars; Unsaturated sugars; Osones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU2007107607/04A 2004-07-29 2005-06-21 ПРОИЗВОДНЫЕ 1-α-ГАЛОГЕН-2,2-ДИФТОР-2-ДЕЗОКСИ-D-РИБОФУРАНОЗЫ И СПОСОБ ИХ ПОЛУЧЕНИЯ RU2346948C2 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2004-0059623 2004-07-29
KR20040059623 2004-07-29
KR1020050041278A KR100699099B1 (ko) 2004-07-29 2005-05-17 1-α-할로-2,2-다이플루오로-2-데옥시-Ｄ-라이보퓨라노스유도체 및 이의 제조방법
KR10-2005-0041278 2005-05-17

Publications (2)

Publication Number Publication Date
RU2007107607A RU2007107607A (ru) 2008-09-10
RU2346948C2 true RU2346948C2 (ru) 2009-02-20

Family

ID=37149831

Family Applications (1)

Application Number Title Priority Date Filing Date
RU2007107607/04A RU2346948C2 (ru) 2004-07-29 2005-06-21 ПРОИЗВОДНЫЕ 1-α-ГАЛОГЕН-2,2-ДИФТОР-2-ДЕЗОКСИ-D-РИБОФУРАНОЗЫ И СПОСОБ ИХ ПОЛУЧЕНИЯ

Country Status (7)

Country Link
JP (1) JP4691101B2 (ja)
KR (1) KR100699099B1 (ja)
CN (1) CN1989148B (ja)
HK (1) HK1100946A1 (ja)
IL (1) IL180894A (ja)
MX (1) MX2007000959A (ja)
RU (1) RU2346948C2 (ja)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008117955A1 (en) 2007-03-23 2008-10-02 Dongwoo Syntech Co., Ltd. Process for preparing of 2'-deoxy-2'2'-difluorocytidine
KR100858842B1 (ko) * 2007-03-23 2008-09-22 동우신테크 주식회사 키랄아민을 이용한 광학활성 옥소라이보스유도체의제조방법
CN101628927B (zh) * 2009-08-07 2012-10-10 卡硼瑞（北京）科技有限公司 以1,3,5-三-O-苯甲酰基-α-D-呋喃核糖为原料立体选择性制备β-二氟胞苷盐酸盐的方法
CN103897008A (zh) * 2012-12-28 2014-07-02 石药集团中奇制药技术（石家庄）有限公司 一种地西他滨及其中间体的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2039403A1 (en) * 1990-04-04 1991-10-05 Gerald Saischek Process for the manufacture of 2-deoxy-d-threo-pentofuranosides, intermediates for their manufacture and their use
CA2098887C (en) * 1992-06-22 2003-10-28 Ta-Sen Chou Process for preparing alpha-anomer enriched 1-halo-2-deoxy-2,2-difluoro-d-ribofuranosyl derivatives
UA67736C2 (uk) * 1997-01-24 2004-07-15 Конфарма Ас Похідні гемцитабіну, спосіб їх одержання та фармацевтична композиція на їх основі
JP2003055364A (ja) * 2001-06-07 2003-02-26 Mitsui Chemicals Inc ２，３−ジデオキシ−２，３−デヒドロペントフラノース誘導体に関する新規製造法

Also Published As

Publication number Publication date
IL180894A0 (en) 2007-07-04
JP4691101B2 (ja) 2011-06-01
KR20060047970A (ko) 2006-05-18
CN1989148B (zh) 2010-05-12
JP2008508261A (ja) 2008-03-21
IL180894A (en) 2011-09-27
MX2007000959A (es) 2007-04-16
KR100699099B1 (ko) 2007-03-22
CN1989148A (zh) 2007-06-27
HK1100946A1 (en) 2007-10-05
RU2007107607A (ru) 2008-09-10

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PC41 Official registration of the transfer of exclusive right

Effective date: 20110420

MM4A The patent is invalid due to non-payment of fees

Effective date: 20140622

PD4A Correction of name of patent owner